Journal of Gastrointestinal Surgery最新文献

{"title":"Transcriptomics Uncovers the Advantages of Magnetic Compression Technique in Gastrointestinal Anastomosis Repair and Regeneration.","authors":"Long Liu, Shuqin Xu, Chentao Li, Jiaru Xu, Linbiao Xiang, Yuning Shao, Miaomiao Zhang, Dinghui Dong, Shuang Bai, Xuemin Liu, Xiaopeng Yan, Yi Lyu","doi":"10.1016/j.gassur.2025.102314","DOIUrl":"https://doi.org/10.1016/j.gassur.2025.102314","url":null,"abstract":"<p><strong>Background: </strong>Magnetic compression technique (MCT) is a novel surgical operation leveraging the 'non-contact' magnetic forces to address challenging clinical issues. The underlying mechanisms of different healing efficacy in gastroenteric anastomosis are still not clarified between MCT and traditional suturing techniques.</p><p><strong>Methods: </strong>A total of twenty male Sprague-Dawley (SD) rats, weighing 200-240g, were randomly and equally divided into traditional suturing (Con) and MCT group. The anastomosis construction time, survival rates, and postoperative complications were compared. Specimens were collected, and RNA sequencing was conducted at two weeks postoperatively, Meanwhile, the burst pressure and histological characteristics were compared between two groups.</p><p><strong>Results: </strong>The anastomosis time of MCT group (6.20 ± 1.51min) was significantly shorter than Con group (15.7 ± 2.43min; P < 0.001). Compared to Con group (80%), the survival rate was significantly higher in the MCT group (100%). No postoperative complications were observed in MCT group. The burst pressure and histological characteristics suggested the MCT group harbored more durable, smoother and fatter surface, complete mucosal migration, less inflammation infiltration, and continuous submucosal layers. The transcriptomics indicated that biological characteristic of MCT group was mainly enriched in energy metabolism, especially for lipid metabolism. The evaluated expression of Nfil3 and Pdk4 could serve as key metabolic molecules regulating anastomotic healing.</p><p><strong>Conclusion: </strong>The MCT presented significant advantages in multiple dimensions, including simple, safety, low postoperative complications. A novel insight was provided that MCT facilitated energy metabolism and further promoted anastomotic healing.</p>","PeriodicalId":15893,"journal":{"name":"Journal of Gastrointestinal Surgery","volume":" ","pages":"102314"},"PeriodicalIF":2.4,"publicationDate":"2026-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145917527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exercise interventions for health-related quality of life, fatigue, depression, and anxiety in colorectal cancer survivors: a systematic review and network meta-analysis","authors":"Hu Tang ,&nbsp;Lin Zhang ,&nbsp;Yangliang Ren ,&nbsp;Yuxiang Wu ,&nbsp;Xiang Zhang ,&nbsp;Yi Dai ,&nbsp;Jian Chen","doi":"10.1016/j.gassur.2026.102320","DOIUrl":"10.1016/j.gassur.2026.102320","url":null,"abstract":"<div><h3>Background</h3><div>Colorectal cancer survivors frequently experience persistent fatigue, psychological distress, and reduced health-related quality of life (HRQoL) after treatment. Exercise is increasingly recognized as an effective nonpharmacologic intervention, but the comparative efficacy of different modalities remains uncertain. This study aimed to evaluate and rank the effects of exercise interventions on HRQoL, fatigue, depression, and anxiety in colorectal cancer survivors through a systematic review and network meta-analysis.</div></div><div><h3>Methods</h3><div>Five databases (PubMed, Embase, Cochrane Central Register of Controlled Trials, Web of Science, and Google Scholar) were searched from inception to October 30, 2025. Eligible randomized controlled trials included adult colorectal cancer survivors receiving structured exercise interventions—such as aerobic exercise (AE), resistance training (RT), combined AE plus RT (AE + RT), yoga, qigong, tai chi, or multicomponent programs—compared with usual care or alternative exercise modalities. Primary outcomes were HRQoL, fatigue, depression, and anxiety assessed after the intervention. Standardized mean differences (SMDs) and 95% CIs were pooled using random-effects models, and comparative rankings were estimated using the surface under the cumulative ranking curve (SUCRA).</div></div><div><h3>Results</h3><div>A total of 22 trials (n = 1676) met the inclusion criteria. Overall, exercise significantly improved HRQoL (SMD, 0.48; 95% CI, 0.28–0.67) and reduced fatigue (SMD, −0.44; 95% CI, −0.70 to −0.19), depression (SMD, −0.29; 95% CI, −0.48 to −0.10), and anxiety (SMD, −0.29; 95% CI, −0.42 to −0.15). Subgroup analyses indicated greater effects with supervised or tele-supervised, moderate-intensity programs (3–5.9 metabolic equivalents of task) in 30- to 60-min sessions, 3 to 4 times weekly for 9 to 23 weeks. Network meta-analysis ranked RT highest for improving HRQoL (SUCRA, 91.8%), and AE + RT most effective for reducing fatigue, depression, and anxiety (SUCRA, 81.7%–82.4%).</div></div><div><h3>Conclusion</h3><div>Exercise significantly enhances HRQoL and psychological well-being in colorectal cancer survivors, with optimal benefits observed from moderate-intensity, supervised, or tele-supervised programs. AE + RT seems the most effective for symptom relief, whereas RT provides the greatest gains in global quality of life.</div></div>","PeriodicalId":15893,"journal":{"name":"Journal of Gastrointestinal Surgery","volume":"30 3","pages":"Article 102320"},"PeriodicalIF":2.4,"publicationDate":"2026-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145906082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Invited commentary on “Body mass index and survival after surgery for gastric adenocarcinoma – a population-based nationwide cohort study in Finland” revisiting the obesity paradox in gastric cancer surgery","authors":"Mio Kitano,&nbsp;Alexander A. Parikh","doi":"10.1016/j.gassur.2025.102310","DOIUrl":"10.1016/j.gassur.2025.102310","url":null,"abstract":"","PeriodicalId":15893,"journal":{"name":"Journal of Gastrointestinal Surgery","volume":"30 3","pages":"Article 102310"},"PeriodicalIF":2.4,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145900485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Defining a new 6-factor Charlson Comorbidity Index utilizing data points available in the American College of Surgeons National Surgical Quality Improvement Program for patients undergoing pancreatoduodenectomy","authors":"John Christopher Polanco-Santana ,&nbsp;João P.G. Kasakewitch ,&nbsp;Kaique Filardi ,&nbsp;Scott C. Fligor ,&nbsp;Manuel Castillo-Angeles ,&nbsp;Tara S. Kent","doi":"10.1016/j.gassur.2025.102319","DOIUrl":"10.1016/j.gassur.2025.102319","url":null,"abstract":"<div><h3>Background</h3><div>The Charlson Comorbidity Index (CCI) is widely used in surgical research to summarize patients’ baseline comorbidities. However, large surgical databases, such as the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP), lack key CCI components, limiting its applicability. Developing a modified CCI (mCCI) using available ACS-NSQIP variables could improve baseline risk stratification for patients undergoing pancreatoduodenectomy (PD). This study aimed to define such an mCCI and evaluate its performance compared with that of the conventional CCI.</div></div><div><h3>Methods</h3><div>This was a 2-phase retrospective study that included patients who underwent PD. In the derivation phase, our institutional ACS-NSQIP database (2015–2021) was used to construct the mCCI, with scores reweighted to the observed 14-point maximum. The Spearman rank correlation was used to evaluate the relationship between CCI and mCCI. The nationwide ACS-NSQIP database (2022) was used for external validation. Unadjusted logistic regression models were constructed to predict discharge disposition and postoperative complications. Model discrimination was evaluated using area under the receiver operating characteristic curve (AUC)/receiver operating characteristic curve analysis with AUCs compared with the DeLong test.</div></div><div><h3>Results</h3><div>A total of 333 institutional and 4867 national patients who underwent PD were included. In the derivation cohort, the mCCI was strongly correlated with the CCI (<em>r</em> = 0.85; <em>P</em> &lt;.001). For discharge disposition, both indices yielded an AUC of 0.74. For postoperative complications, AUCs were 0.50 for CCI and 0.55 for mCCI. Similar trends were observed in external validation. No significant differences were found in the discriminatory capacities between the models.</div></div><div><h3>Conclusion</h3><div>mCCI is a reasonable alternative to account for baseline comorbidities in patients undergoing PD using the ACS-NSQIP database. Further studies should refine weighting schemes across diverse populations to optimize mCCI performance.</div></div>","PeriodicalId":15893,"journal":{"name":"Journal of Gastrointestinal Surgery","volume":"30 4","pages":"Article 102319"},"PeriodicalIF":2.4,"publicationDate":"2025-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145889214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stapled Kono-S anastomosis as a protective strategy against postoperative endoscopic recurrence in ileocolonic Crohn’s disease: a dual-center retrospective cohort analysis","authors":"Zhouhang Dai ,&nbsp;Ming Duan ,&nbsp;Wei Liu ,&nbsp;Xiaolong Ge ,&nbsp;Lei Cao ,&nbsp;Wei Zhou ,&nbsp;Yi Li","doi":"10.1016/j.gassur.2025.102318","DOIUrl":"10.1016/j.gassur.2025.102318","url":null,"abstract":"","PeriodicalId":15893,"journal":{"name":"Journal of Gastrointestinal Surgery","volume":"30 3","pages":"Article 102318"},"PeriodicalIF":2.4,"publicationDate":"2025-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145889198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative effectiveness of exercise modalities on psychological outcomes and quality of life in digestive system cancer survivors: a systematic review and network meta-analysis","authors":"Jiaqi Li,&nbsp;Qian Zhang,&nbsp;Wei Ning,&nbsp;Zhenzi Wang","doi":"10.1016/j.gassur.2025.102313","DOIUrl":"10.1016/j.gassur.2025.102313","url":null,"abstract":"<div><h3>Background</h3><div>Survivors of digestive system cancers frequently experience depression, anxiety, fatigue, and impaired health-related quality of life (HRQoL). Exercise has emerged as a promising adjunctive therapy. However, the optimal modality and prescription remain unclear. This study aimed to evaluate the effects of exercise on psychological outcomes and HRQoL, to rank the relative efficacy of different modalities, and to identify optimal exercise characteristics through subgroup analyses.</div></div><div><h3>Methods</h3><div>PubMed, Embase, CENTRAL, Web of Science, and Google Scholar were searched until August 31, 2025, for randomized controlled trials (RCTs) of exercise interventions in adult survivors of digestive system cancers. Eligible comparators included usual care, no intervention, or alternative exercise. The primary outcomes were HRQoL, fatigue, depression, and anxiety, which were measured using validated instruments. The standardized mean differences (SMDs) with 95% CIs were used as effect estimates. Pairwise meta-analyses were performed with random-effects models, and Bayesian network meta-analysis was used to compare exercise modalities. Subgroup analyses were used to examine moderators, including cancer type, exercise intensity, frequency, session duration, and intervention length.</div></div><div><h3>Results</h3><div>A total of 38 RCTs that involved 3255 participants were included. The exercise group significantly had improved HRQoL (SMD, 0.43 [95% CI, 0.27–0.59]) and reduced fatigue (SMD, −0.52 [95% CI, −0.72 to −0.32]), depression (SMD, −0.37 [95% CI, −0.58 to −0.15]), and anxiety (SMD, −0.33 [95% CI, −0.44 to −0.21]) compared with the control group. Network meta-analysis indicated that mind-body exercise (such as yoga or tai chi) was most effective for HRQoL (SMD, 0.68 [95% CI, 0.22–1.14]) and depression (SMD, −0.55 [95% CI, −0.95 to −0.16]), resistance training for fatigue (SMD, −0.79 [95% CI, −1.35 to −0.23]), and combined training (CT) for anxiety (SMD, −0.38 [95% CI, −0.53 to −0.23]). Subgroup analyses showed that moderate-intensity, moderate-frequency, and medium-to-long interventions produced the most consistent benefits.</div></div><div><h3>Conclusion</h3><div>Exercise interventions significantly improved HRQoL and reduced depression, anxiety, and fatigue in survivors of digestive system cancers. Mind-body exercise (eg, yoga or tai chi) demonstrated the greatest benefits for HRQoL and depression, resistance training best alleviated fatigue, and CT reduced anxiety. Moderate-intensity, sustained programs achieved the most consistent benefits, supporting individualized exercise prescriptions in survivorship care.</div></div>","PeriodicalId":15893,"journal":{"name":"Journal of Gastrointestinal Surgery","volume":"30 3","pages":"Article 102313"},"PeriodicalIF":2.4,"publicationDate":"2025-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145878464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative fluid management in pancreaticoduodenectomy in the era of goal-directed fluid therapy: a review of the literature","authors":"Meghan Grim,&nbsp;Richard Zheng,&nbsp;Nader Hanna,&nbsp;Harish Lavu,&nbsp;Charles J. Yeo,&nbsp;Avinoam Nevler","doi":"10.1016/j.gassur.2025.102316","DOIUrl":"10.1016/j.gassur.2025.102316","url":null,"abstract":"<div><h3>Background</h3><div>Pancreaticoduodenectomy (PD) is the only curative option for localized pancreatic head and periampullary malignancies. However, PD is associated with significant perioperative morbidity. Perioperative fluid management has emerged as an important modifiable factor influencing surgical outcomes in PD.</div></div><div><h3>Methods</h3><div>In this qualitative review, PubMed/Medline searches were performed between March and August 2025 to review the terms “pancreaticoduodenectomy,” “fluid management,” “Enhanced Recovery After Surgery,” “complications,” and related terms.</div></div><div><h3>Results</h3><div>Historically, liberal fluid administration was favored to compensate for third-space losses, but contemporary evidence has linked excessive fluid volumes to complications, such as postoperative pancreatic fistula, anastomotic edema, and increased inflammatory responses. Recent studies, including those utilizing Enhanced Recovery After Surgery (ERAS) protocols, indicate the possible benefit of more restrictive fluid regimens, finding that restrictive fluids are associated with reduced overall complications, lower cardiopulmonary morbidity, and shorter post-operative hospital stays, amongst others. However, overly restrictive strategies may risk hypoperfusion, driving the necessity for a delicate balance between restrictive fluid administration and physiologic demand.</div></div><div><h3>Conclusions</h3><div>Goal-directed fluid therapy protocols offer a promising approach to PD fluid management by individualizing fluid delivery, minimizing complications, and improving perfusion metrics, resulting in a more effective restrictive fluid approach. Despite these advancements, heterogeneity in study designs, fluid management definitions, and monitoring tools limits a clear consensus. Future research should prioritize multicenter randomized controlled trials, standardized protocols, and long-term outcome assessments to refine evidence-based, patient-centered fluid management strategies in PD.</div></div>","PeriodicalId":15893,"journal":{"name":"Journal of Gastrointestinal Surgery","volume":"30 3","pages":"Article 102316"},"PeriodicalIF":2.4,"publicationDate":"2025-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145856762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biological, mechanical, and immune changes in an abdominal rectus fascia transplant model in rats","authors":"Jeremias Elias Moreira ,&nbsp;Ivana Ivanoff ,&nbsp;Marco Santillán Pazmiño ,&nbsp;Pedro Martín ,&nbsp;Verónica Milesi ,&nbsp;Pablo Stringa ,&nbsp;Anastasios D. Giannou ,&nbsp;Lucrecia Cúneo ,&nbsp;Fernando Ogresta ,&nbsp;Araceli Castro ,&nbsp;Augusto Pellegrino Damelio ,&nbsp;Martín Eleta ,&nbsp;María Virginia Gentilini ,&nbsp;Martín Rumbo ,&nbsp;Gabriel Eduardo Gondolesi","doi":"10.1016/j.gassur.2025.102306","DOIUrl":"10.1016/j.gassur.2025.102306","url":null,"abstract":"<div><h3>Background</h3><div>Primary abdominal wall closure after intestinal and multivisceral transplants remains a challenge. Avascular transplant of the abdominal rectus fascia (TxARF) has emerged as an alternative to reduce postoperative morbidity and mortality. This study aimed to evaluate tissue and immunological responses to TxARF in a rat model without immunosuppression.</div></div><div><h3>Methods</h3><div>A total of 34 TxARFs were performed in rats (17 isogenic [ISO] and 17 allogeneic [ALLO]), with recipients sacrificed at 30 and 120 days after surgery. Serum and graft samples were analyzed for donor-specific antibodies (DSAs), elasticity, cellular analysis by flow cytometry, histopathology, and immunohistochemistry for CD3+ cells.</div></div><div><h3>Results</h3><div>Muscle fiber loss was observed at 30 days, with collagen content significantly higher in ALLO (55.97 ± 3.68) and ISO (33.13 ± 3.85) groups than controls (3.78 ± 0.47) (<em>P</em> &lt;.0001). The lateral portions of the grafts showed more large blood vessels, whereas the medial areas had small vessels. The ALLO group exhibited increased resistance to stretching and elasticity loss. Despite the lack of immunosuppression, CD3+ levels in all groups were similar to controls, with only 1 animal showing a positive DSA response.</div></div><div><h3>Conclusion</h3><div>Long-term changes include muscle fiber replacement with fibrosis and loss of elasticity, especially in the alloreactive group. No significant immune response occurred, confirming the fascia’s low immunogenicity.</div></div>","PeriodicalId":15893,"journal":{"name":"Journal of Gastrointestinal Surgery","volume":"30 2","pages":"Article 102306"},"PeriodicalIF":2.4,"publicationDate":"2025-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145843759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the editor regarding “Sixteen years of microwave ablation: a homogeneous dataset or a mirror of technical evolution?”","authors":"Xiaoming Zhang ,&nbsp;Zhenbo Shu","doi":"10.1016/j.gassur.2025.102317","DOIUrl":"10.1016/j.gassur.2025.102317","url":null,"abstract":"","PeriodicalId":15893,"journal":{"name":"Journal of Gastrointestinal Surgery","volume":"30 3","pages":"Article 102317"},"PeriodicalIF":2.4,"publicationDate":"2025-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145843747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A modified gastric tube reconstruction after laparoscopic proximal gastrectomy for early adenocarcinoma in the upper third stomach and esophagogastric junction: short-term surgical outcomes","authors":"Yi Liao ,&nbsp;Wengcheong Tam ,&nbsp;Hao Chen ,&nbsp;Jintuan Huang ,&nbsp;Jun Xiang ,&nbsp;Chunyu Chen ,&nbsp;Zuli Yang","doi":"10.1016/j.gassur.2025.102315","DOIUrl":"10.1016/j.gassur.2025.102315","url":null,"abstract":"<div><h3>Background</h3><div>Proximal gastrectomy with conventional esophagogastrostomy is frequently associated with postoperative complications, including significant reflux esophagitis. This study aimed to evaluate a modified reconstruction technique that combines gastric tube (GT) formation with overlap anastomosis and partial fundoplication.</div></div><div><h3>Methods</h3><div>Between January 2021 and January 2024, 29 consecutive patients diagnosed with early-stage proximal gastric cancer underwent laparoscopic proximal gastrectomy using our novel reconstruction method. The surgical protocol included the creation of a GT conduit, overlap esophagogastric anastomosis, and partial fundoplication procedure. Perioperative outcomes and postoperative follow-up data were prospectively collected.</div></div><div><h3>Results</h3><div>The cohort demonstrated a mean operative time of 239 ± (SD) 50 min and a median estimated blood loss of 50 mL (IQR, 20–150). Lymph node dissection yielded a median count of 25 nodes (IQR, 9–66). Postoperative complications included 1 case (3.4%) of anastomotic leakage requiring conservative management. Mild reflux symptoms (heartburn) were transiently observed in 2 patients (6.9%), both resolving with short-term proton pump inhibitor therapy. Endoscopic evaluation at the 3-month follow-up revealed grade A or B reflux esophagitis (Los Angeles classification) in 2 patients (6.9%). Nutritional parameters (serum albumin and total protein levels) showed expected postoperative declines during the initial 3-month period, followed by progressive recovery to preoperative baseline values by 6 months postoperatively (<em>P</em> &lt;.05 for longitudinal comparison).</div></div><div><h3>Conclusion</h3><div>Our preliminary findings suggest that GT reconstruction with overlap anastomosis and partial fundoplication is a technically feasible and safe approach for proximal gastrectomy, demonstrating acceptable short-term functional outcomes with mitigated reflux complications.</div></div>","PeriodicalId":15893,"journal":{"name":"Journal of Gastrointestinal Surgery","volume":"30 3","pages":"Article 102315"},"PeriodicalIF":2.4,"publicationDate":"2025-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145843773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}