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Fatigue Performance and Failure Loads of Composition-Gradient Multilayer Zirconia: Partial-Coverage Restorations Versus Single Crowns at Different Thicknesses. 成分梯度多层氧化锆的疲劳性能和失效载荷:不同厚度的部分覆盖修复体与单冠修复体。
IF 4.1 3区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-03 DOI: 10.1111/jerd.70066
F A Spitznagel, A Marksteiner, L S Prott, Y Zhang, M B Blatz, L M M Alves, T M B Campos, P C Gierthmuehlen

Objective: This study investigated the influence of restoration type (partial-coverage versus crown) and ceramic-layer thickness on the fatigue behavior and failure load of monolithic composition-gradient multilayer zirconia (4Y-PSZ/5Y-PSZ) molar restorations.

Material and methods: Seventy-two CAD/CAM-fabricated monolithic zirconia restorations (IPS e.max ZirCAD-Prime-Esthetic, Ivoclar-Vivadent) were assigned to six groups (n = 12), based on restoration type-partial-coverage restoration (PCR) or crown (C)-and ceramic thickness (occlusal/buccal: 0.5/0.4, 1.0/0.6, or 1.5/0.8 mm). All restorations were adhesively bonded to standardized dentin-analogue dies. Specimens underwent thermomechanical fatigue (1.2 million cycles, 49 N, 1.6 Hz, 5°C-55°C), followed by single load to failure testing. Data were analyzed using ANOVA, Tukey's post hoc test, and independent t-tests (α = 0.05).

Results: All specimens survived fatigue. Evident cracks were observed post-fatigue; one each in PCR-0.5 and C-0.5 groups, resulting in an overall success rate of 97.22%. Mean failure loads (N) were: PCR-0.5: 2047, PCR-1.0: 2018, PCR-1.5: 2777, C-0.5: 695, C-1.0: 1957, C-1.5: 3503. Ultrathin (0.5 mm) PCRs demonstrated significantly higher failure loads than ultrathin crowns (p < 0.001), whereas crowns at 1.5 mm thickness outperformed PCRs (p = 0.005). No significant difference was observed at 1.0 mm thickness (p = 0.634).

Conclusion: At ultrathin thicknesses (0.5 mm), partial-coverage designs showed superior failure loads over crowns. Both restoration types are mechanically viable at 1.0 mm and 1.5 mm thicknesses.

Clinical significance: Composition-gradient multilayer-zirconia demonstrates high fatigue resistance and is well-suited for minimally invasive, non-retentive PCR molar restorations. However, a minimum thickness of 1.0 mm should be maintained for single crowns.

目的:研究修复类型(部分覆盖vs全冠)和陶瓷层厚度对整体成分梯度多层氧化锆(4Y-PSZ/5Y-PSZ)磨牙修复体疲劳行为和破坏载荷的影响。材料和方法:根据修复类型-部分覆盖修复(PCR)或冠(C)和陶瓷厚度(咬合/颊:0.5/0.4,1.0/0.6或1.5/0.8 mm),将72个CAD/ cam制造的整体氧化锆修复体(IPS e.max zircad - prime - aesthetic, Ivoclar-Vivadent)分为6组(n = 12)。所有修复体均粘附在标准化牙本质模拟物模具上。试件进行了热力疲劳试验(120万次循环,49 N, 1.6 Hz, 5°C-55°C),然后进行单载荷失效试验。数据分析采用方差分析、Tukey事后检验和独立t检验(α = 0.05)。结果:所有试件均在疲劳状态下存活。疲劳后观察到明显的裂纹;PCR-0.5组和C-0.5组各1例,总成功率为97.22%。平均失效载荷(N)为:PCR-0.5: 2047, PCR-1.0: 2018, PCR-1.5: 2777, C-0.5: 695, C-1.0: 1957, C-1.5: 3503。结论:在超薄厚度(0.5 mm)下,部分覆盖设计比冠具有更强的破坏载荷。两种修复类型在1.0 mm和1.5 mm厚度下都是机械可行的。临床意义:成分梯度多层氧化锆具有较高的抗疲劳性,非常适合微创、非固位PCR磨牙修复。但是,对于单个冠,应保持至少1.0 mm的厚度。
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引用次数: 0
Dentin Hypersensitivity and Gingival Recession: Impact of Root Surface Coverage-A Retrospective Study. 牙本质过敏和牙龈萎缩:根面覆盖的影响——一项回顾性研究。
IF 4.1 3区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-03 DOI: 10.1111/jerd.70065
Romain Ohanessian, Angéline Antezack, Alexandre Feuillette, Cyril Ferrier, Virginie Monnet-Corti

Objective: To assess whether root surface coverage after periodontal plastic surgery is associated with significant dentin hypersensitivity suppression.

Materials and methods: Included patients presented a significant dentin hypersensitivity (Schiff score ≥ 2) and gingival recession. Treatment consisted of periodontal plastic surgery for root coverage. At 6 months, significant dentin hypersensitivity prevalence was assessed. Surgical outcomes were evaluated by measuring the percentage of root surface coverage and the height of root coverage, both in pixels and millimeters, in two groups: teeth without significant dentin hypersensitivity and those with persistent significant dentin hypersensitivity.

Results: Significant dentin hypersensitivity prevalence was 6.8% (95% CI [1.0%-12.5%]), with suppression in 93.2% of treated teeth 6 months postoperatively. Complete root surface coverage (CRSCpix) was achieved in 69.6% without dentin hypersensitivity, significantly higher than 0.0% in teeth with dentin hypersensitivity (p = 0.0041). Complete root height coverage in pix (CRHCpix) was 63.8% without dentin hypersensitivity versus (vs) 20.0% with DH (p = 0.0737), while complete root height coverage in mm (CRHCmm) was 76.8% without DH vs. 40.0% with dentin hypersensitivity (p = 0.1033). Mean root surface coverage in pixels (RSCpix) was 88.3% ± 19.7% without DH, significantly higher than 62.6% ± 28.2% with dentin hypersensitivity (p = 0.0031). Mean root height coverage in pixels (RHCpix) was 83.2% ± 28.3% without DH versus 68.8% ± 35.1% with dentin hypersensitivity (p = 0.0573), while mean root height coverage in millimeters (RHCmm) was 88.2% ± 24.7% without dentin hypersensitivity versus 73.3% ± 30.8% with dentin hypersensitivity (p = 0.0503). No significant differences were found for height-based root coverage in pixels (RHCpix) and millimeters (RHCmm).

Conclusion: Success of surgical root coverage, particularly the amount of root surface covered, could be a key factor in dentin hypersensitivity suppression.

目的:评估牙周整形术后根面覆盖是否与抑制牙本质过敏相关。材料和方法:纳入的患者有明显的牙本质过敏(希夫评分≥2)和牙龈萎缩。治疗包括牙周整形手术以覆盖牙根。6个月时,评估了明显的牙本质过敏患病率。通过测量牙根表面覆盖的百分比和牙根覆盖的高度(以像素和毫米为单位)来评估两组患者的手术效果:无明显牙本质过敏的牙齿和持续明显牙本质过敏的牙齿。结果:牙本质过敏发生率为6.8% (95% CI[1.0% ~ 12.5%]),术后6个月有93.2%的牙本质过敏抑制。无牙本质过敏的69.6%的牙根表面完全覆盖(CRSCpix),明显高于牙本质过敏的0.0% (p = 0.0041)。无牙本质过敏症时,根高覆盖率(CRHCpix)为63.8%,有DH时为20.0% (p = 0.0737);无DH时,根高覆盖率(CRHCmm)为76.8%,有DH时为40.0% (p = 0.1033)。无牙本质过敏症的牙根表面覆盖(RSCpix)为88.3%±19.7%,显著高于牙本质过敏症的62.6%±28.2% (p = 0.0031)。无牙本质过敏症的平均根高覆盖率(RHCpix)为83.2%±28.3%,无牙本质过敏症的为68.8%±35.1% (p = 0.0573);无牙本质过敏症的平均根高覆盖率(RHCmm)为88.2%±24.7%,有牙本质过敏症的为73.3%±30.8% (p = 0.0503)。以像素(RHCpix)和毫米(RHCmm)为单位的基于高度的根系覆盖度无显著差异。结论:手术根面覆盖的成功与否,特别是根面覆盖面积的多少,可能是抑制牙本质过敏的关键因素。
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引用次数: 0
Comprehensive Orthodontic Approach to Iatrogenic Uprighting, Apical Root Resorption, and Gingival Recession of the Maxillary Incisors With Transverse Discrepancy. 上颌门牙横向差异医源性直立、根尖吸收和牙龈退缩的综合正畸治疗方法。
IF 4.1 3区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-03 DOI: 10.1111/jerd.70071
Mi-Young Lee, Jae Hyun Park, Ju-Young Lee, Na-Young Chang, Jong-Moon Chae

Objective: This case report presents the retreatment of a patient who experienced iatrogenic complications resulting from inadequate orthodontic diagnosis and treatment. The objective was to mitigate further risks and correct the underlying clinical issues.

Clinical considerations: A 23-year-old female patient presented with iatrogenic uprighting, apical root resorption, and gingival recession of the maxillary incisors following inappropriate orthodontic treatment. She also exhibited a transverse maxillary deficiency, which contributed to an unstable posterior occlusion and an anterior open bite. Orthodontic retreatment involved microimplant-assisted rapid palatal expansion (MARPE) to address the transverse discrepancy, resulting in improved posterior occlusion and successful closure of the anterior open bite.

Conclusion: Consequently, root angulation of the maxillary canines was corrected using a box loop wire, while torque control of the maxillary incisor roots was carefully managed to ensure their alignment within the alveolar bone housing.

Clinical significance: In young adults, a transverse maxillary deficiency can be effectively managed using MARPE, which also contributes to improvements in vertical skeletal relationships. When iatrogenic root resorption and gingival recession result from improper root positioning, repositioning the affected roots may help prevent further resorption and enhance periodontal stability. Such orthodontic complications are frequently associated with excessive space closure following tooth extraction, inappropriate biomechanical strategies, prolonged treatment duration, and extensive tooth movement.

目的:本病例报告介绍了一位因正畸诊断和治疗不充分而导致医源性并发症的患者的再治疗。目的是减轻进一步的风险和纠正潜在的临床问题。临床分析:一名23岁女性患者在不适当的正畸治疗后出现医源性上颌门牙直立、根尖吸收和牙龈退缩。她还表现出上颌横向缺陷,导致后牙合不稳定和前牙开咬。正畸再治疗包括微种植体辅助快速腭扩张(MARPE)来解决横向差异,从而改善后牙合并成功关闭前开咬。结论:因此,上颌犬根的角度矫正使用盒环金属丝,而上颌切牙根的扭矩控制是仔细管理,以确保其在牙槽骨壳内对齐。临床意义:在年轻人中,使用MARPE可以有效地治疗上颌横向缺陷,这也有助于改善垂直骨骼关系。当因牙根定位不当导致医源性牙根吸收和牙龈退缩时,重新定位受影响的牙根有助于防止进一步的吸收,增强牙周的稳定性。这些正畸并发症通常与拔牙后空间封闭过度、不适当的生物力学策略、治疗时间延长和牙齿移动过大有关。
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引用次数: 0
Tooth-Supported 3D-Printed Surgical Guide for Titanium Mesh Placement in Bone Augmentation of the Esthetic Zone. 牙支撑型3d打印钛网置入美学区骨增强手术指南。
IF 4.1 3区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-28 DOI: 10.1111/jerd.70063
Geru Zhang, Liwei Huang, Yang Gao, Xiaoxiao Cai

Objective: To describe a tooth-supported, 3D-printed surgical guide designed to enable accurate intraoperative placement of titanium mesh for bone augmentation in the esthetic zone, in accordance with the preoperative design.

Clinical consideration: Titanium mesh supported guided bone regeneration (GBR) is a widely accepted technique for bone augmentation due to its strong spatial support and predictable osteogenesis. However, intraoperative deviations in titanium mesh placement may affect the final outcome of bone augmentation. This case series presents a tooth-supported titanium mesh positioning guide, fabricated through personalized 3D printing, which allows in situ fixation of the mesh during the augmentation procedure.

Conclusion: The guide enabled precise intraoperative positioning of the titanium mesh in accordance with the preoperative design. The maximum intraoperative titanium mesh displacement was 1.59 mm, with an average deviation of 0.42 mm. The average overall bone augmentation volume deviation was 0.057 ± 0.031 cm3(SD), 95% CI: (0.025 cm3, 0.089cm3), corresponding to a bone augmentation accuracy of 91.67%.

Clinical significance: This tooth-supported positioning guide accurately transfers the preoperative design to titanium mesh-supported guided bone regeneration surgery, thereby improving the accuracy of titanium mesh placement. It facilitates a standardized and controlled workflow for bone augmentation, enhancing the predictability of outcomes in the esthetic zone.

目的:描述一种牙齿支撑的3d打印手术指南,旨在根据术前设计,术中准确放置用于骨增强的钛网在美观区。临床考虑:钛网支撑引导骨再生(GBR)由于其强大的空间支撑和可预测的成骨,是一种被广泛接受的骨增强技术。然而,术中钛网放置的偏差可能会影响骨增强的最终结果。本案例系列介绍了一种牙齿支撑的钛网定位指南,通过个性化3D打印制造,允许在增强过程中原位固定网。结论:该指南可使术中钛网按照术前设计精确定位。术中钛网最大位移1.59 mm,平均偏移0.42 mm。总体平均骨增强体积偏差为0.057±0.031 cm3(SD), 95% CI为(0.025 cm3, 0.089cm3),骨增强精度为91.67%。临床意义:该牙支撑定位导具将术前设计准确地转移到钛网支撑引导骨再生手术中,从而提高钛网放置的准确性。它促进了骨增强的标准化和控制工作流程,增强了美学区域结果的可预测性。
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引用次数: 0
Customized Connective Tissue Graft Technique for Optimizing Interproximal Attachment Gain in Regenerative Treatment of Infrabony Defects: A Case Report With 36- to 56-Month Follow-Up. 自定义结缔组织移植技术在骨下缺损再生治疗中优化近端间附着增益:一个36至56个月随访的病例报告。
IF 4.1 3区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-26 DOI: 10.1111/jerd.70061
Michel Bravard, Kevimy Agossa, Hom-Lay Wang

Objective: The aim of this retrospective case report was to evaluate the long-term effect of a customized connective tissue graft technique (c-CTG) aimed at preserving or enhancing buccal and interproximal soft tissues in the context of regenerative treatment of infrabony defects in the esthetic zone.

Clinical considerations: Three patients presenting with a single, deep periodontal infrabony defect between the maxillary central incisors were treated using the c-CTG. All sites demonstrated regenerative success, defined as a clinical attachment gain of ≥ 3 mm and probing depth ≤ 4 mm, maintained over a 3- to 5-year follow-up period. In Case 1, complete resolution of pre-existing buccal recession was observed, along with a 2 mm increase in papilla height. Case 2 showed partial closure of a postoperative black triangle, with progressive papilla gain between 6 and 24 months. In Case 3, the initial interproximal gingival crater evolved into a positive soft tissue architecture that was maintained over the long term.

Conclusion: Based on the findings, the c-CTG appears to be a feasible approach for achieving both predictable regenerative outcomes and long-term enhancements in both buccal and interdental soft tissue contours.

目的:本回顾性病例报告的目的是评估一种定制结缔组织移植技术(c-CTG)的长期效果,该技术旨在保存或增强颊和近端间软组织,以再生治疗美观区骨下缺损。临床观察:3例患者表现为上颌中切牙之间的单一深度牙周下颌骨缺损,采用c-CTG治疗。所有部位均显示再生成功,定义为临床附着增加≥3mm,探入深度≤4mm,并在3至5年随访期间保持。在病例1中,观察到先前存在的颊退缩完全消退,同时乳头高度增加2mm。病例2显示术后黑色三角形部分闭合,6至24个月间乳头增加。在病例3中,最初的近端牙龈间凹坑演变成一个积极的软组织结构,并长期维持。结论:基于这些发现,c-CTG似乎是一种可行的方法,既可以实现可预测的再生结果,又可以长期增强颊和牙间软组织轮廓。
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引用次数: 0
Perception of Orofacial Esthetics Using a Scan-Free Virtual Video Mock-Up: A Comparative Analysis of Self-Evaluation Versus Unknown-People Assessment. 使用无扫描虚拟视频模型的口腔面部美学感知:自我评价与未知人评价的比较分析。
IF 4.1 3区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-26 DOI: 10.1111/jerd.70059
Aspasia Pachiou, Miha Pirc, Tim Joda, Ronald E Jung, Alexis Ioannidis

Objective: To evaluate perceptions of scan-free virtual video mock-ups using the Orofacial Esthetic Scale (OES), comparing self-assessments and evaluations of anonymized individuals by dental professionals and laypeople.

Materials and methods: This study was conducted at the Clinic of Reconstructive Dentistry, University of Zurich. Fifty participants (25 dental professionals and 25 laypeople) were video recorded under standardized conditions while smiling, turning from en face to profile, and speaking to simulate dynamic facial movements. Recordings were obtained using a clinical capture application linked to the device's native rear camera, and AI-generated scan-free virtual video mock-ups were returned within minutes. Each participant rated their own mock-up using the Orofacial Esthetic Scale (OES) and, in randomized order, evaluated five anonymized virtual mock-ups generated from the software library (based on real patient recordings but fully de-identified for privacy protection). Median OES scores were compared using Wilcoxon signed-rank and Mann-Whitney U tests (α = 0.05).

Results: Fifty participants (25 dentists and 25 laypeople) were included. Overall, ratings improved from baseline to the scan-free virtual video mock-up for tooth color and alignment (p = 0.003 and p = 0.014), while no significant changes were observed for the remaining items. In subgroup analyses, laypeople reported significant improvements in tooth color, alignment, form, and overall esthetics after Holm correction, whereas no differences were found among dentists. For mock-up ratings, laypeople assigned higher scores than dentists across all OES items (all p < 0.05), except for tooth alignment and facial profile. When assessing anonymized mock-ups of other individuals, laypeople consistently rated all eight items significantly higher than dentists.

Conclusions: Within the limitations of this study, it was concluded that lay participants assigned higher esthetic ratings than dental professionals for virtual video mock-ups of themselves and of unknown individuals. Comparisons between self-evaluation and evaluation of anonymized individuals showed no consistent differences among dentists, while several item-level differences were observed among lay participants. Compared with natural dentition, ratings for tooth color and tooth alignment increased after viewing the virtual mock-up, while other items did not change significantly.

Clinical significance: These findings suggest that integrating simplified digital simulations with patient-reported outcome measures enhances communication, aligns expectations, and supports patient-centered shared decision-making in prosthodontic and implant treatment planning.

目的:利用口腔面部美学量表(OES)评价对免扫描虚拟视频模型的感知,比较牙科专业人员和外行人的自我评价和匿名个人的评价。材料和方法:本研究在苏黎世大学牙科重建诊所进行。50名参与者(25名牙科专业人员和25名外行人)在标准化条件下微笑、从正面转向侧面、说话以模拟动态面部运动的录像。录音是通过与设备内置后置摄像头相连的临床捕捉应用程序获得的,人工智能生成的无需扫描的虚拟视频模型在几分钟内返回。每位参与者使用口腔面部美学量表(OES)对自己的模型进行评分,并按随机顺序评估软件库生成的五个匿名虚拟模型(基于真实患者记录,但出于隐私保护而完全去识别)。OES得分中位数比较采用Wilcoxon符号秩检验和Mann-Whitney U检验(α = 0.05)。结果:共纳入50名参与者(25名牙医和25名外行人)。总体而言,评分从基线到无扫描的牙齿颜色和对齐虚拟视频模型有所改善(p = 0.003和p = 0.014),而其余项目没有明显变化。在亚组分析中,外行人报告了Holm矫正后牙齿颜色、排列、形状和整体美观的显著改善,而在牙医中没有发现差异。对于实物评分,外行人在所有OES项目上的评分都高于牙医(所有p)。结论:在本研究的局限性内,得出的结论是,外行人参与者对自己和未知个体的虚拟视频实物评分高于牙科专业人员。在自我评价和匿名个体评价的比较中,牙医之间没有一致的差异,而在非专业参与者中观察到几个项目水平的差异。与自然牙列相比,观看虚拟模型后,牙齿颜色和牙齿排列的评分增加了,而其他项目没有明显变化。临床意义:这些研究结果表明,将简化的数字模拟与患者报告的结果测量相结合,可以加强沟通,协调期望,并支持以患者为中心的修复和种植治疗计划的共同决策。
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引用次数: 0
Impact of Phosphoric Acid Etching Duration on the Bonding Performance of Universal Adhesives on Enamel: A Systematic Review of Laboratory Studies. 磷酸刻蚀时间对通用胶粘剂与牙釉质粘接性能的影响:实验室研究的系统综述。
IF 4.1 3区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-26 DOI: 10.1111/jerd.70057
Tarek Amran, Jeronim Esati, Roland Weiger, Markus B Blatz, Florin Eggmann

Objective: The optimal duration of phosphoric acid etching (PAE) for enamel bonding remains uncertain, particularly in the context of universal adhesives. The aim of this systematic review was to determine whether shortened etching times (< 15 s) provide comparable bond strength to conventional protocols.

Materials and methods: Searches were conducted across four databases, including Embase, OpenGrey through DANS, PubMed, and Scopus. Laboratory studies on human or bovine enamel specimens, treated with varying PAE durations prior to the application of universal adhesives, were included. Data regarding etching protocols, adhesive types, substrate preparation (ground vs. unground enamel), and bond strength outcomes were analyzed. Risk of bias was evaluated using the RoBDEMAT tool.

Results: Of 762 records screened, eight laboratory studies met inclusion criteria. Etching times of 3-15 s achieved bond strengths that were statistically non-inferior to conventional durations, with no added benefit from prolonged etching. Ground enamel consistently showed enhanced bond strength with PAE, whereas unground enamel exhibited similar bonding trends. The risk of bias was most often due to inadequate sample size justification, deficiencies in randomization, and absence of blinding.

Conclusions: Short-duration PAE (3-15 s) appears sufficient for effective bonding of universal adhesives to enamel, while minimizing potential risk of over-etching of adjacent dentin. Future research should focus on tailoring etching protocols based on cavity-specific characteristics and exploring alternative pretreatment methods to enhance bonding performance.

Clinical significance: This review suggests that abbreviated phosphoric acid etching (3-15 s) provides enamel bond strengths equivalent to conventional durations when universal adhesives are used. This approach may reduce the risk of inadvertent dentin over-etching in mixed-substrate cavities while maintaining optimal adhesive performance.

目的:磷酸蚀刻(PAE)用于牙釉质粘接的最佳时间仍然不确定,特别是在通用粘合剂的情况下。本系统综述的目的是确定是否缩短了蚀刻时间(材料和方法:在四个数据库中进行了搜索,包括Embase、OpenGrey、PubMed和Scopus。包括在应用通用粘合剂之前用不同PAE持续时间处理的人类或牛牙釉质标本的实验室研究。分析了蚀刻方案、粘合剂类型、基材制备(研磨搪瓷与未研磨搪瓷)和粘合强度结果的数据。使用RoBDEMAT工具评估偏倚风险。结果:在筛选的762份记录中,有8份实验室研究符合纳入标准。蚀刻时间为3-15秒,获得的键强度在统计上不低于传统的持续时间,并且没有从长时间蚀刻中获得额外的好处。磨光的牙釉质与PAE的结合强度持续增强,而未磨光的牙釉质则表现出类似的结合趋势。偏倚的风险通常是由于样本量不足、随机化的缺陷和缺乏盲法。结论:短时间PAE (3- 15s)足以使万能粘接剂与牙釉质有效结合,同时将邻牙本质过度蚀刻的潜在风险降至最低。未来的研究应侧重于根据空腔特性定制蚀刻方案,并探索替代预处理方法以提高粘合性能。临床意义:本综述表明,当使用通用粘接剂时,缩短磷酸蚀刻(3-15 s)提供的牙釉质结合强度相当于传统的持续时间。这种方法可以在保持最佳粘合性能的同时,降低混合基板牙本质过度腐蚀的风险。
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引用次数: 0
Performance of Multimodal Generative AI Models in Addressing Complex Dental Inquiries With Text, Images, and Analytical Data 多模态生成AI模型在处理具有文本、图像和分析数据的复杂牙科查询中的性能。
IF 4.1 3区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-25 DOI: 10.1111/jerd.70064
Hang-Nga Mai, Du-Hyeong Lee, Jekita Kaenploy, Jong-Eun Kim, Seok-Hwan Cho

Objective

Multimodal large language models (LLMs) have the potential to transform dental learning and decision-making by addressing multimodal dental inquiries that integrate text, images, and analytical data. The purpose of this study was to evaluate the performance of various multimodal LLMs in responding to multimodal dental queries and to identify factors influencing their performance.

Materials and Methods

Four multimodal LLMs (ChatGPT-4V, Claude 3 Sonnet, Microsoft 365 Copilot 2024, and Google Gemini 1.5 Pro) were evaluated based on their correct answers and passing margin for the Integrated National Board Dental Examination (INBDE) and the Advanced Dental Admission Test (ADAT). Descriptive statistics, χ 2 tests, Cohen's κ, Kruskal–Wallis tests, and Mann–Whitney U tests were used to analyze the performance across different question types, independent inputs, and picture types (α = 0.05).

Results

Claude 3 Sonnet outperformed the other models in both INBDE and ADAT exams, achieving the highest accuracy, followed by ChatGPT-4V, Microsoft 365 Copilot 2024, and Google Gemini 1.5 Pro. χ 2 tests revealed significant differences between chatbots in the ADAT exam, but not in the INBDE. Cohen's κ showed weak to moderate model agreement for INBDE and stronger agreement for ADAT, with the highest agreement between Claude 3 Sonnet and ChatGPT-4V (κ = 0.757) and the lowest between Google Gemini 1.5 Pro and Microsoft 365 Copilot 2024 (κ = 0.059). Model performance was influenced by question type (theoretical and clinical), with common errors including misinterpreting clinical scenarios, visual data difficulties, and dental terminology ambiguities.

Conclusion

Multimodal LLMs show potential in answering multimodal dental inquiries, though performance varies across models, with challenges in interpreting clinical scenarios, visual data, and terminology ambiguity.

Clinical Significance

Large language models canbe applied not only to memorization-type but also interpretation andproblem-solving cognitive questions in dentistry. Tomaximize the utility of these artificial intelligence models, users need bothan understanding of their differences and the ability to manage complexclinical data.

目的:多模态大语言模型(llm)有潜力通过解决整合文本、图像和分析数据的多模态牙科查询来改变牙科学习和决策。本研究的目的是评估各种多模式llm在响应多模式牙科查询方面的表现,并确定影响其表现的因素。材料和方法:根据四个多模式llm (ChatGPT-4V, Claude 3 Sonnet, Microsoft 365 Copilot 2024和谷歌Gemini 1.5 Pro)的正确答案和通过国家综合委员会牙科考试(INBDE)和高级牙科入学考试(ADAT)的边际进行评估。采用描述性统计、χ2检验、Cohen’s κ检验、Kruskal-Wallis检验和Mann-Whitney U检验分析不同问题类型、独立输入和图片类型的表现(α = 0.05)。结果:Claude 3 Sonnet在INBDE和ADAT测试中均优于其他型号,准确率最高,其次是ChatGPT-4V、Microsoft 365 Copilot 2024和谷歌Gemini 1.5 Pro。χ2检验显示聊天机器人在ADAT考试中有显著差异,但在INBDE考试中没有显著差异。其中,Claude 3 Sonnet和ChatGPT-4V之间的一致性最高(κ = 0.757),谷歌Gemini 1.5 Pro和Microsoft 365 Copilot 2024之间的一致性最低(κ = 0.059)。模型性能受到问题类型(理论和临床)的影响,常见的错误包括对临床情景的误解、视觉数据困难和牙科术语歧义。结论:多模态llm在回答多模态牙科咨询方面显示出潜力,尽管不同模型的表现不同,在解释临床场景、视觉数据和术语歧义方面存在挑战。临床意义:大型语言模型不仅可以应用于记忆型认知问题,还可以应用于牙科认知问题的解释和解决。为了最大限度地发挥这些人工智能模型的效用,用户既需要了解它们之间的差异,也需要有能力管理复杂的临床数据。
{"title":"Performance of Multimodal Generative AI Models in Addressing Complex Dental Inquiries With Text, Images, and Analytical Data","authors":"Hang-Nga Mai,&nbsp;Du-Hyeong Lee,&nbsp;Jekita Kaenploy,&nbsp;Jong-Eun Kim,&nbsp;Seok-Hwan Cho","doi":"10.1111/jerd.70064","DOIUrl":"10.1111/jerd.70064","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Multimodal large language models (LLMs) have the potential to transform dental learning and decision-making by addressing multimodal dental inquiries that integrate text, images, and analytical data. The purpose of this study was to evaluate the performance of various multimodal LLMs in responding to multimodal dental queries and to identify factors influencing their performance.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Four multimodal LLMs (ChatGPT-4V, Claude 3 Sonnet, Microsoft 365 Copilot 2024, and Google Gemini 1.5 Pro) were evaluated based on their correct answers and passing margin for the Integrated National Board Dental Examination (INBDE) and the Advanced Dental Admission Test (ADAT). Descriptive statistics, <i>χ</i>\u0000 <sup>2</sup> tests, Cohen's <i>κ</i>, Kruskal–Wallis tests, and Mann–Whitney <i>U</i> tests were used to analyze the performance across different question types, independent inputs, and picture types (<i>α</i> = 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Claude 3 Sonnet outperformed the other models in both INBDE and ADAT exams, achieving the highest accuracy, followed by ChatGPT-4V, Microsoft 365 Copilot 2024, and Google Gemini 1.5 Pro. <i>χ</i>\u0000 <sup>2</sup> tests revealed significant differences between chatbots in the ADAT exam, but not in the INBDE. Cohen's <i>κ</i> showed weak to moderate model agreement for INBDE and stronger agreement for ADAT, with the highest agreement between Claude 3 Sonnet and ChatGPT-4V (<i>κ</i> = 0.757) and the lowest between Google Gemini 1.5 Pro and Microsoft 365 Copilot 2024 (<i>κ</i> = 0.059). Model performance was influenced by question type (theoretical and clinical), with common errors including misinterpreting clinical scenarios, visual data difficulties, and dental terminology ambiguities.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Multimodal LLMs show potential in answering multimodal dental inquiries, though performance varies across models, with challenges in interpreting clinical scenarios, visual data, and terminology ambiguity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Significance</h3>\u0000 \u0000 <p>Large language models canbe applied not only to memorization-type but also interpretation andproblem-solving cognitive questions in dentistry. Tomaximize the utility of these artificial intelligence models, users need bothan understanding of their differences and the ability to manage complexclinical data.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15988,"journal":{"name":"Journal of Esthetic and Restorative Dentistry","volume":"38 1","pages":"166-172"},"PeriodicalIF":4.1,"publicationDate":"2025-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145596643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Performance of Bulk-Fill Versus Incremental Layering Techniques in Class II Restorations: A Systematic Review and Network Meta-Analysis. II类修复体中填充体与增量分层技术的临床表现:系统综述和网络荟萃分析。
IF 4.1 3区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-25 DOI: 10.1111/jerd.70060
Alain Manuel Chaple Gil, Laura Pereda Vázquez, Meylin Santiesteban Velázquez, Lazareth Liz Ortiz Santiago, Elizabeth Jiménez Hernández

Introduction: The promise of faster, simpler restorations has driven the rise of bulk-fill composites, but do speed and simplicity come at the cost of longevity and marginal integrity?

Objective: To compare and rank the clinical performance of bulk-fill and conventional incremental layering restoration techniques in Class II posterior restorations through a network meta-analysis (NMA).

Methods: Following PRISMA 2020 guidelines, a comprehensive electronic search was conducted across five databases. Twelve randomized clinical trials met the eligibility criteria. Risk of bias was assessed using RoB2, and confidence in evidence was evaluated through CINeMA. Network meta-analyses at 6, 12, and 24 months estimated relative risks for marginal adaptation, fractures, and retention using random-effects models.

Results: Across all follow-ups, no statistically significant differences were observed between bulk-fill and incremental techniques. Risk ratios clustered around unity, and P-scores indicated minimal ranking variability, confirming comparable outcomes among bulk-fill subtypes regardless of viscosity or curing mode. Most evidence was rated as low risk of bias with acceptable indirectness. CINeMA indicated predominantly low concerns for indirectness and risk of bias, supporting the robustness and transitivity of the network. The ormocer-based and overlay bulk-fill composites showed the highest, though not statistically superior, ranking probabilities at 12 and 24 months.

Conclusion: Across 6-, 12-, and 24-month follow-ups, no statistically significant differences were detected between bulk-fill techniques and incremental placement for the primary outcomes (marginal adaptation, fractures, and retention). Treatment rankings (P-scores) showed minimal separation overall; ormocer-based and overlay bulk-fill configurations tended to occupy higher ranks at 12-24 months, but without statistically confirmed superiority.

Clinical significance: This systematic review and network meta-analysis provides robust, evidence-based guidance to support clinical decision-making in the restoration of posterior Class II cavities. The findings indicate that bulk-fill resin composites regardless of viscosity or formulation demonstrate clinical performance comparable to conventional incremental layering techniques, while markedly simplifying placement procedures and enhancing operative efficiency.

Trial registration: This review was prospectively registered in the International Prospective Register of Systematic Reviews (PROSPERO; registration number CRD420251170292).

快速、简单修复的前景推动了大块填充复合材料的兴起,但速度和简单是否以寿命和边际完整性为代价?目的:通过网络荟萃分析(network meta-analysis, NMA)比较块状充填和常规增量层状修复技术在II类后牙体修复中的临床表现并进行排名。方法:按照PRISMA 2020指南,在五个数据库中进行全面的电子检索。12个随机临床试验符合入选标准。使用RoB2评估偏倚风险,通过CINeMA评估证据的置信度。网络荟萃分析在6、12和24个月时使用随机效应模型估计了边际适应、骨折和保留的相对风险。结果:在所有随访中,未观察到体积填充和增量技术之间的统计学差异。风险比聚集在统一周围,p分数表明最小的排名变异性,证实了无论粘度或固化模式如何,散装填料亚型之间的可比结果。大多数证据被评为低偏倚风险,具有可接受的间接性。CINeMA主要表明对间接性和偏见风险的关注较低,支持网络的稳健性和传递性。在12个月和24个月时,基于ormoer和覆盖体填充的复合材料显示出最高的排序概率,尽管在统计上并不优越。结论:在6个月、12个月和24个月的随访中,在主要结果(边缘适应、骨折和固位)方面,大块填充技术和增量置入之间没有统计学上的显著差异。治疗排名(p分数)总体上显示最小的分离;在12-24个月时,基于ormoer和覆盖体填充的配置往往占据较高的排名,但没有统计证实的优势。临床意义:本系统综述和网络荟萃分析为支持后牙II类腔修复的临床决策提供了强有力的循证指导。研究结果表明,无论粘度或配方如何,大块填充树脂复合材料的临床性能与传统的增量分层技术相当,同时显着简化了放置程序并提高了手术效率。试验注册:本综述在国际前瞻性系统评论注册(PROSPERO,注册号CRD420251170292)中前瞻性注册。
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引用次数: 0
To Bleach or Not to Bleach?-The Role of Bleaching in the Clinical Workflow for the Treatment of Demarcated Opacities in Anterior Teeth. 漂白还是不漂白?漂白在治疗前牙有界混浊的临床工作流程中的作用。
IF 4.1 3区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-24 DOI: 10.1111/jerd.70056
Linda Greenwall, Marcus Cebula, Joseph Greenwall-Cohen, Falk Schwendicke, Susanne Effenberger

Objective: To present a structured, stepwise approach for the esthetic management of demarcated anterior opacities associated with molar-incisor hypomineralization (MIH), emphasizing the role of bleaching within a minimally invasive treatment workflow.

Clinical considerations: Discoloration of anterior teeth, particularly MIH-related opacities, can significantly affect Psychosocial well-being and overall health. Recommended interventions range from non-invasive and microinvasive techniques, such as bleaching and resin infiltration, to more invasive options like composite restorations. Due to the variability in opacities, a combination of treatment modalities is often necessary. From a clinical workflow perspective, MIH-affected anterior teeth can be categorized into basic, advanced, and complex cases, depending on their appearance and anticipated treatment needs. This clinical report demonstrates the proposed stepwise approach in five cases: two basic, two advanced, and one complex, illustrating how complexity guides treatment selection.

Conclusion: A minimally invasive approach should be prioritized for managing MIH-related anterior discolorations. Bleaching serves as an important first-line option before considering more invasive alternatives, thereby preserving hard tooth structure-an especially critical consideration in pediatric patients.

Clinical significance: Implementing a systematic, minimally invasive treatment protocol for MIH-affected anterior teeth can enhance esthetic outcomes while maintaining tooth integrity, thereby improving patient confidence, identity and quality of life.

目的:提出一种结构化的、分步的方法来美学处理与磨牙-切牙低矿化(MIH)相关的有界前牙混浊,强调漂白在微创治疗流程中的作用。临床注意事项:前牙变色,特别是与mih相关的混浊,可显著影响心理社会健康和整体健康。推荐的干预措施包括非侵入性和微创技术,如漂白和树脂浸润,以及更有侵入性的选择,如复合修复。由于混浊的可变性,通常需要多种治疗方式的组合。从临床工作流程的角度来看,mih影响的前牙根据其外观和预期的治疗需求可分为基础,晚期和复杂病例。本临床报告在五个病例中展示了建议的逐步方法:两个基本,两个进展,一个复杂,说明复杂性如何指导治疗选择。结论:微创入路治疗mih相关性前病变应优先考虑。在考虑更有侵入性的替代方案之前,漂白是重要的一线选择,从而保留坚硬的牙齿结构——这是儿科患者特别重要的考虑因素。临床意义:对mih影响的前牙实施系统的微创治疗方案,可以在保持牙齿完整性的同时提高美观效果,从而提高患者的信心、身份和生活质量。
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引用次数: 0
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Journal of Esthetic and Restorative Dentistry
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