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Role of Oral Pregabalin as Premedication in Attenuation of Hemodynamic Responses to Laryngoscopy, Intubation, and Extubation in Patients Undergoing Laparoscopic Cholecystectomy: A Randomized Clinical Trial 口服普瑞巴林作为预用药在降低腹腔镜胆囊切除术患者喉镜检查、插管和拔管后血流动力学反应中的作用:一项随机临床试验
Pub Date : 2020-10-15 DOI: 10.5005/jp-journals-10057-0094
D. Jethava, Sudhir Sachdev, Aman Malawat, Shubhra Gupta, Khayyam Moin
Background and aim: Direct laryngoscopy, tracheal intubation, and extubation contribute to augmentation in heart rate and blood pressure. This can precipitate serious complications in patients with coronary artery disease, intracranial neuropathology, or reactive airways. Attenuation of hemodynamic stress response to laryngoscopy, intubation, and extubation is essential for better anesthetic outcome. The aim of this study was to evaluate the effect of oral pregabalin as premedication in attenuation of hemodynamic stress response to laryngoscopy, intubation, and extubation. Materials and methods: This prospective randomized double-blinded placebo controlled study was conducted with 60 patients of American Society of Anesthesiologists (ASA) physical status class I/II, undergoing elective laparoscopic cholecystectomy. Patients were allocated randomly into two groups receiving either oral placebo or oral pregabalin 150 mg, 120 minutes before induction of anesthesia. Hemodynamic parameters such as heart rate, systolic, diastolic, and mean blood pressures were compared at various time points. Results: Pregabalin showed a significant attenuation of hemodynamic stress response to laryngoscopy, tracheal intubation, and extubation compared with that of placebo. The pregabalin premedicated patients remained hemodynamically stable perioperatively without any significant side effects. Conclusion: Pregabalin is effective in attenuating hemodynamic stress response to laryngoscopy, tracheal intubation, and extubation.
背景和目的:直接喉镜检查、气管插管和拔管有助于提高心率和血压。这可导致冠状动脉疾病、颅内神经病变或反应性气道患者出现严重并发症。降低喉镜检查、插管和拔管后的血流动力学应激反应对获得更好的麻醉效果至关重要。本研究的目的是评估口服普瑞巴林作为预用药在降低喉镜检查、插管和拔管后的血流动力学应激反应中的作用。材料和方法:本前瞻性随机双盲安慰剂对照研究纳入60例美国麻醉医师学会(ASA)身体状态为I/II级的择期腹腔镜胆囊切除术患者。患者被随机分为两组,分别在麻醉诱导前120分钟口服安慰剂或口服普瑞巴林150mg。血流动力学参数如心率、收缩压、舒张压和平均血压在不同时间点进行比较。结果:与安慰剂相比,普瑞巴林对喉镜检查、气管插管和拔管的血流动力学应激反应有显著的减弱。预用药患者围手术期血流动力学稳定,无明显副作用。结论:普瑞巴林能有效降低喉镜检查、气管插管和拔管后的血流动力学应激反应。
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引用次数: 0
A Case Report of Hydrops Fetalis with Cystic Hygroma 水肿胎儿合并囊性水肿1例报告
Pub Date : 2020-10-15 DOI: 10.5005/jp-journals-10057-0107
H. Mishra, P. Agarwal, S. Rahi, M. C. Baberwal
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引用次数: 0
Meticulous History and Examination: Still Remains the Backbone of Diagnosis 细致的病史和检查:仍然是诊断的支柱
Pub Date : 2020-10-15 DOI: 10.5005/jp-journals-10057-0103
U. Sharma, Umang Juneja, S. Garg
A high degree of suspicion and an ectopic conscious clinician is required for diagnosis of ectopic pregnancy. Only when you suspect it, a detailed history of the patient and a meticulous examination will reveal the presence of an ectopic pregnancy, which can then be confirmed by the appropriate bedside investigations. The cases of ectopic pregnancy where the diagnosis is delayed or, which are misdiagnosed, carry a high morbidity and mortality, as the morbidity and mortality associated with ectopic pregnancy is directly related to the length of time required for diagnosis. We report three such cases of ectopic pregnancy where the diagnosis was delayed due to variable and unpredictable presentations, in whom the initial history and examination was missed as the presence of ectopic pregnancy was not suspected by the presentation.
诊断异位妊娠需要高度的怀疑和异位意识。只有当你怀疑时,详细的病史和细致的检查才能揭示异位妊娠的存在,然后通过适当的床边检查来确认。由于异位妊娠的发病率和死亡率与诊断所需的时间长短直接相关,因此,诊断延迟或误诊的异位妊娠具有很高的发病率和死亡率。我们报告了三个这样的异位妊娠的情况下,诊断延迟,由于变化和不可预测的表现,其中最初的历史和检查被遗漏,因为异位妊娠的存在没有怀疑的表现。
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引用次数: 0
Unusual Severe Superolateral Dislocation of Right Condyle Associated with Sagittal Split of Articular Eminence in Pan-facial Trauma Managed with Inverted L-plate: A Case Report 倒置l型钢板治疗泛面外伤时异常严重的右髁上外侧脱位伴关节隆起矢状分裂1例
Pub Date : 2020-10-15 DOI: 10.5005/jp-journals-10057-0106
Ruchika Tiwari, V. Singh, V. Jamdade, K. Jay, Y. Sharma
Head and neck trauma is a challenging case for a maxillofacial surgeon because not only preinjury anatomy needs to be achieved but also esthetic has to be improved. Management of such patients is quite challenging and also requires a frequent multidisciplinary team intervention. One of the cause of such trauma is unprotected driving or high-velocity collision. 1 Pan-facial trauma not only disrupts normal facial anatomy but also hinders normal functions like vision (dystopia, diplopia, enophthalmos), respiration (airway) and olfactory senses, mastication and natural occlusion and intercuspation, deglutition, and overall asthetic of the patient. Restoring and rehabilitation of preinjury contour of facial skeleton in such patient of trauma requires artistic work of the operating maxillofacial surgeon. The treatment modality in case of trauma is open reduction and internal fixation (ORIF) under general anesthesia (GA). Various approaches have been suggested to achieve near normal anatomy. Past research suggested “top to bottom” or “bottom to top” along with “outward to inward” or “inward to outward,” The main aim being restoring horizontal and vertical facial pillars.
头颈部创伤对颌面外科医生来说是一个具有挑战性的病例,因为不仅需要达到损伤前解剖,而且还需要改善美学。这类患者的管理相当具有挑战性,也需要频繁的多学科团队干预。造成这种创伤的原因之一是无保护的驾驶或高速碰撞。1泛面外伤不仅破坏了正常的面部解剖结构,还影响了患者的正常功能,如视力(异位、复视、眼球内陷)、呼吸(气道)、嗅觉、咀嚼和自然咬合、咀嚼、吞咽、整体审美等。这类创伤患者面部骨骼损伤前轮廓的恢复与康复需要颌面外科手术医师的艺术性。创伤的治疗方式是全麻下切开复位内固定(ORIF)。已经提出了各种方法来实现接近正常的解剖。过去的研究建议采用“从上到下”或“从下到上”,以及“从外到内”或“从内到外”,主要目的是恢复水平和垂直的面部支柱。
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引用次数: 0
Oral Cavity “A Window to Systemic Illness”: A Case Report of Gingival Enlargement Secondary to Acute Leukemia 口腔“全身性疾病的窗口”:急性白血病继发牙龈肿大1例报告
Pub Date : 2020-10-15 DOI: 10.5005/jp-journals-10057-0105
Harshdeep Dhaliwal, Vikram Sharma, A. Jamdade, S. Yadav, Divya Rana
Oral signs and symptoms most of the times indicate a local disease and can be treated with dental treatment; however, sometimes it can be an indication of any underlying severe disease. Acute myeloid leukemia is one such grave hematological malignancy with a very short lifespan if undiagnosed and left untreated, which shows oral signs as the first clinical manifestations of the disease. This is a case report where oral findings lead to diagnosis of acute myeloid leukemia in a 55-year-old female.
口腔体征和症状大多数时候表明是局部疾病,可以通过牙科治疗来治疗;然而,有时它可能是任何潜在的严重疾病的迹象。急性髓性白血病是一种严重的血液系统恶性肿瘤,如果不及时诊断和治疗,其生命周期非常短,口腔体征是该病的首要临床表现。这是一个病例报告,口腔检查导致诊断急性髓性白血病在一个55岁的女性。
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引用次数: 0
Management of Sodium Hypochlorite Accident: A Case Report 次氯酸钠事故处理1例报告
Pub Date : 2020-10-15 DOI: 10.5005/jp-journals-10057-0095
A. Prasad, Deepak Raisingani, Harshit Srivastava, Anubha Sejra, N. Mittal, Garima Udawat
Root canal treatment, or endodontic treatment, is a procedure frequently done to debride, disinfect, and remove residual microorganisms found in infected root canals of teeth. Certain chemicals have been found to be effective in disinfecting the root canal system with different success rates. Sodium hypochlorite (NaOCl) is a common irrigation solution and disinfectant used in root canal treatment. It has strong antibacterial and tissue-dissolving properties. Although it is a potential irrigant, but severe complications can occur when it comes into contact with soft tissue especially due to its cytotoxic features, some of which are life-threatening. This case report documents successful management after accidental extrusion of NaOCl into the periapical area and explains precautionary management protocols for such cases.
根管治疗或牙髓治疗是一种常用的清除、消毒和清除感染牙齿根管中残留微生物的方法。某些化学物质已被发现对根管系统有效消毒,成功率不同。次氯酸钠(NaOCl)是根管治疗中常用的冲洗液和消毒剂。它具有很强的抗菌和组织溶解性能。虽然它是一种潜在的冲洗剂,但当它与软组织接触时,特别是由于其细胞毒性的特点,可能会发生严重的并发症,其中一些是危及生命的。本病例报告记录了意外挤压NaOCl进入根尖周区域后的成功管理,并解释了此类病例的预防性管理方案。
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引用次数: 0
Endodontic Management of External Apical Root Resorption: A Case Report 根管治疗外根尖吸收1例
Pub Date : 2020-10-15 DOI: 10.5005/jp-journals-10057-0101
Prachi Mittal, A. Prasad, Deepak Raisingani, Harshit Srivastava, Nikita Sarraf, Akansha Jharwal
Resorption is the combination of either physiological or pathological factors that results in the loss of dentin, cementum, and the alveolar bone of tooth structure due to the action of polynuclear giant cells. The most frequent causative factor for resorption is local factors, notably excessive pressure and inflammatory process. Different types of resorption have been classified depending upon its etiology and site, and different treatment regimens have been proposed based on the type of resorption present. External apical root resorption is usually pathological. The case in this article demonstrates external root resorption managed with nonsurgical root canal therapy with the use intracanal medicament of calcium hydroxide, with 1 month follow-up revealing arrest of resorption. Subsequent follow-up at 6 months shows complete repair of periradicular and furcation area.
吸收是由于多核巨细胞的作用,导致牙本质、牙骨质、牙槽骨等牙齿结构的丧失,是生理和病理因素共同作用的结果。最常见的导致吸收的因素是局部因素,特别是过度的压力和炎症过程。不同类型的吸收根据其病因和部位进行分类,并根据吸收的类型提出了不同的治疗方案。外根尖吸收通常是病理性的。本病例采用非手术根管治疗,并使用根管内氢氧化钙治疗,1个月随访发现外根吸收停止。6个月随访显示根周和分叉区完全修复。
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引用次数: 0
Tongue-tie Management: A Case Report 舌结管理:一例报告
Pub Date : 2020-10-15 DOI: 10.5005/jp-journals-10057-0096
Swati Sharma, M. Meena, Ashishkumar T Yadav, Amrita Kumari, M. Bansal, Karan H Asrani, Akanksha Gaud
Tongue-tie or ankyloglossia is a rare congenital anomaly. It is a short, thick, and fibrosed lingual frenulum which causes restriction in function of the tongue and also in speech. Tongue is an accessory organ, and it helps in deglutition, mastication, and speech. Tongue-tie also causes lingual recession of the teeth. So, it is necessary to treat at the right time. In this case, the patient has a lingual tongue-tie which has been treated by using a diode laser.
舌系带或咬紧带是一种罕见的先天性异常。舌系带是一种短而厚且纤维化的舌系带,它会限制舌头的功能和说话。舌头是辅助器官,它帮助吞咽、咀嚼和说话。打结也会导致牙齿的舌状凹陷。所以,及时治疗是很有必要的。在这种情况下,病人有舌结,已经用二极管激光治疗。
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引用次数: 1
A Rare Case of Arteriovenous Malformation of Mandible: A Case Report 罕见的下颌骨动静脉畸形1例
Pub Date : 2020-10-15 DOI: 10.5005/jp-journals-10057-0100
Ruchika Tiwari, V. Singh, P. Agarwal, G. Thanvi, Vandita Chaurasia
Arteriovenous malformation (AVM) is a congenital disorder of the veins and arteries that makeup the vascular system. This report presents a case of AVM in the body and ramus region of left side of mandible in a 22-year-old male. The case presents with diffuse swelling present on left region of the body and ramus area of mandible since 8 months. Malformation was diagnosed with the help of detailed patient history, clinical evaluation, radiographs, and computed tomography (CT) scans. The definitive diagnosis was made by CT angiography. Later hemimandibulectomy with simultaneous reconstruction by a titanium plate was done.
动静脉畸形(AVM)是构成血管系统的静脉和动脉的先天性疾病。本文报告一例22岁男性下颌骨左侧分支区及身体的AVM。该病例8个月来表现为身体左侧及下颌骨分支区弥漫性肿胀。通过详细的患者病史、临床评估、x线片和计算机断层扫描来诊断畸形。最终诊断为CT血管造影。后来进行了半下颌管切除术并同时用钛板重建。
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引用次数: 2
Unusual Swelling in the Head and Neck Region 头颈部异常肿胀
Pub Date : 2020-10-15 DOI: 10.5005/jp-journals-10057-0098
Vipasha Yogi, Sanjoy Baruah, P. Vyas, K. Sharma
These are case series with six patients who presented unusual neck swelling. Worldwide, the most common swelling in the neck region is a enlargement of cervical lymph nodes. Each country has a different etiology and geographical distribution for cervical lymphadenopathy. Tuberculosis, metastatic cancers, and lymphomas are the commonest causes. However, in clinical practice, we encounter rare neck swelling. Such swellings are due to their less common and unusual presentation, and its clinical diagnosis is rarely attained. In such cases, proper diagnosis and management are required to attain the desired results. Materials and methods: In our tertiary healthcare center, we encountered such case in ENT OPD. Five cases were evaluated in this article along with their management. Such rare causes of neck swellings are therapeutically challenging, as they cause diagnostic dilemmas. Results: Histopathology and immunohistochemistry were the mainstay of diagnosis, and surgery was curative in most cases.
这是6例出现异常颈部肿胀的患者的病例系列。在世界范围内,颈部最常见的肿胀是颈部淋巴结肿大。每个国家都有不同的病因和颈部淋巴结病的地理分布。结核病、转移性癌症和淋巴瘤是最常见的病因。然而,在临床实践中,我们遇到罕见的颈部肿胀。这种肿胀是由于其不常见和不寻常的表现,其临床诊断很少得到。在这种情况下,需要适当的诊断和管理,以达到预期的结果。材料和方法:在我们三级保健中心,我们在耳鼻喉科遇到了这样的病例。本文对5例病例进行了评价,并对其处理进行了探讨。这些罕见的颈部肿胀原因在治疗上具有挑战性,因为它们会导致诊断困境。结果:组织病理学和免疫组化检查是诊断的主要方法,手术治疗效果好。
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引用次数: 0
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Journal of Mahatma Gandhi University of Medical Sciences and Technology
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