Introduction: Urinary drainage (ureteral stenting or percutaneous nephrostomy) is commonly used for malignant ureteral obstruction (MUO), but optimal indications remain unclear. [99mTc]Tc-mercaptoacetyltriglycine (MAG3) renal scintigraphy assesses urinary tract obstruction and may help identify patients who can avoid drainage. The aim of this case series was to investigate the impact of urinary drainage guided by MAG3 findings on renal function in MUO patients.
Methods: We retrospectively reviewed 44 MUO patients who underwent MAG3 scintigraphy between April 2020 and January 2022. Based on results, 29 patients underwent urinary drainage and 15 patients were treated conservatively. Patients were classified by MAG3 excretion pattern and followed by renal function, pyelonephritis and flank pain at 1, 2, 3 and 6 months.
Results: Among the conservative group (n = 15), MAG3 patterns included non-function (n = 7), delayed excretion (n = 7) and obstruction (n = 1). No patients developed renal deterioration or pyelonephritis, though one patient underwent drainage for contralateral flank pain. Among the drainage group (n = 29), MAG3 patterns included obstruction (n = 16), delayed excretion (n = 8), declined excretion (n = 3) and non-function (n = 2).
Conclusion: Fourteen of 15 patients treated conservatively after MAG3 scintigraphy experienced no renal complications during 6 months of follow-up. MAG3 scintigraphy may support individualised decision-making and help avoid unnecessary drainage. Conservative management may be appropriate for patients with a non-functional MAG3 pattern.
{"title":"A Qualitative Review of Clinical Decision-Making Using [<sup>99m</sup>Tc]Tc-Mercaptoacetyltriglycine Renal Scintigraphy in Patients With Malignant Ureteral Obstruction.","authors":"Akira Ohtsu, Seiji Arai, Tirso Peña, Yusuke Otani, Mai Onose-Kato, Yusuke Tsuji, Tatsuhiro Sawada, Yuji Fujizuka, Yoshitaka Sekine, Hidekazu Koike, Tetsuya Higuchi, Kazuhiro Suzuki","doi":"10.1002/jmrs.70029","DOIUrl":"https://doi.org/10.1002/jmrs.70029","url":null,"abstract":"<p><strong>Introduction: </strong>Urinary drainage (ureteral stenting or percutaneous nephrostomy) is commonly used for malignant ureteral obstruction (MUO), but optimal indications remain unclear. [<sup>99m</sup>Tc]Tc-mercaptoacetyltriglycine (MAG<sub>3</sub>) renal scintigraphy assesses urinary tract obstruction and may help identify patients who can avoid drainage. The aim of this case series was to investigate the impact of urinary drainage guided by MAG<sub>3</sub> findings on renal function in MUO patients.</p><p><strong>Methods: </strong>We retrospectively reviewed 44 MUO patients who underwent MAG<sub>3</sub> scintigraphy between April 2020 and January 2022. Based on results, 29 patients underwent urinary drainage and 15 patients were treated conservatively. Patients were classified by MAG<sub>3</sub> excretion pattern and followed by renal function, pyelonephritis and flank pain at 1, 2, 3 and 6 months.</p><p><strong>Results: </strong>Among the conservative group (n = 15), MAG<sub>3</sub> patterns included non-function (n = 7), delayed excretion (n = 7) and obstruction (n = 1). No patients developed renal deterioration or pyelonephritis, though one patient underwent drainage for contralateral flank pain. Among the drainage group (n = 29), MAG<sub>3</sub> patterns included obstruction (n = 16), delayed excretion (n = 8), declined excretion (n = 3) and non-function (n = 2).</p><p><strong>Conclusion: </strong>Fourteen of 15 patients treated conservatively after MAG<sub>3</sub> scintigraphy experienced no renal complications during 6 months of follow-up. MAG<sub>3</sub> scintigraphy may support individualised decision-making and help avoid unnecessary drainage. Conservative management may be appropriate for patients with a non-functional MAG<sub>3</sub> pattern.</p>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145280404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Luísa Soares, Isabel Bravo, José Guilherme Couto
This letter highlights the valuable contribution of the review titled 'Quantifying the Carbon Footprint of External Beam Radiation Therapy-A Narrative Review' (https://doi.org/10.1002/jmrs.70009) in understanding how radiation therapy impacts healthcare-related greenhouse gas emissions, particularly through pre-treatment imaging, treatment delivery, and patient travel. Therefore, the letter emphasizes that empowering radiation therapists with green skills is essential to foster a culture of environmental responsibility within radiation therapy departments.
{"title":"Letter to the Editor Regarding Quantifying the Carbon Footprint of External Beam Radiation Therapy-A Narrative Review.","authors":"Ana Luísa Soares, Isabel Bravo, José Guilherme Couto","doi":"10.1002/jmrs.70028","DOIUrl":"https://doi.org/10.1002/jmrs.70028","url":null,"abstract":"<p><p>This letter highlights the valuable contribution of the review titled 'Quantifying the Carbon Footprint of External Beam Radiation Therapy-A Narrative Review' (https://doi.org/10.1002/jmrs.70009) in understanding how radiation therapy impacts healthcare-related greenhouse gas emissions, particularly through pre-treatment imaging, treatment delivery, and patient travel. Therefore, the letter emphasizes that empowering radiation therapists with green skills is essential to foster a culture of environmental responsibility within radiation therapy departments.</p>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nazli A Moda, Mo'ayyad E Suleiman, Sahand Hooshmand, Warren M Reed
Breast cancer is the most commonly diagnosed cancer among women worldwide, and concerns regarding radiation exposure from mammography screening remain a potential barrier to participation. This scoping review explores existing models estimating long-term radiation risks associated with repeated mammography screening. A structured search across five databases (Medline, Embase, Scopus, Web of Science and CINAHL) along with manual searching identified 24 studies published between 2014 and 2024. These were categorised into three themes: (1) models estimating dose-risk profiles, (2) factors affecting radiation dose and (3) the use of artificial intelligence (AI) in dose estimation and mammographic breast density (MBD) estimation. Studies showed that breast density, compressed breast thickness (CBT) and technical imaging parameters significantly influence mean glandular dose (MGD). Modelling studies highlighted the low risk of radiation-induced cancer, inconsistencies in protocols and vendor-specific limitations. AI applications are emerging as promising tools for improving individualised dose-risk assessments but require further development for compatibility across different imaging platforms.
乳腺癌是全世界妇女中最常见的诊断癌症,对乳房x光检查的辐射暴露的担忧仍然是参与的潜在障碍。本综述探讨了与重复乳房x光检查相关的长期辐射风险的现有模型。通过五个数据库(Medline, Embase, Scopus, Web of Science和CINAHL)的结构化搜索以及人工搜索,确定了2014年至2024年间发表的24项研究。这些研究分为三个主题:(1)估计剂量-风险概况的模型;(2)影响辐射剂量的因素;(3)人工智能(AI)在剂量估计和乳房x线摄影乳腺密度(MBD)估计中的应用。研究表明,乳腺密度、压缩乳腺厚度(CBT)和技术成像参数对平均腺体剂量(MGD)有显著影响。模型研究强调了辐射诱发癌症的低风险、协议的不一致以及供应商特定的限制。人工智能应用正在成为改善个性化剂量风险评估的有前途的工具,但需要进一步开发不同成像平台之间的兼容性。
{"title":"Radiation Risk in 2D Mammography Screening: A Scoping Review of Modelling Strategies and Emerging AI Applications.","authors":"Nazli A Moda, Mo'ayyad E Suleiman, Sahand Hooshmand, Warren M Reed","doi":"10.1002/jmrs.70022","DOIUrl":"https://doi.org/10.1002/jmrs.70022","url":null,"abstract":"<p><p>Breast cancer is the most commonly diagnosed cancer among women worldwide, and concerns regarding radiation exposure from mammography screening remain a potential barrier to participation. This scoping review explores existing models estimating long-term radiation risks associated with repeated mammography screening. A structured search across five databases (Medline, Embase, Scopus, Web of Science and CINAHL) along with manual searching identified 24 studies published between 2014 and 2024. These were categorised into three themes: (1) models estimating dose-risk profiles, (2) factors affecting radiation dose and (3) the use of artificial intelligence (AI) in dose estimation and mammographic breast density (MBD) estimation. Studies showed that breast density, compressed breast thickness (CBT) and technical imaging parameters significantly influence mean glandular dose (MGD). Modelling studies highlighted the low risk of radiation-induced cancer, inconsistencies in protocols and vendor-specific limitations. AI applications are emerging as promising tools for improving individualised dose-risk assessments but require further development for compatibility across different imaging platforms.</p>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145225534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mikaela Doig, Andrew Cunningham, Victoria Bedford, Hien Le, Matthew O'Connor, Sophie Jessop, Eva Bezak, Nayana Parange, Amanda Hutchinson, Peter Gorayski, Michala Short
Introduction: Health-related quality of life (HRQoL) outcomes are not routinely collected in paediatric radiation therapy (RT). This study co-designed and evaluated an electronic platform to support routine HRQoL assessment using patient-reported outcome measures (PROMs).
Methods: A digital platform was developed following a user-centred design approach. Development included planning with consumers and clinicians, identifying user needs through interviews and iterative design refinements. Alpha testing was performed with consumers. Beta testing involved directed tasks by children, parents and clinician participants to evaluate the developed platform. Thematic analysis of participant feedback was performed to identify refinements and shape clinical implementation strategies.
Results: Iterative alpha testing with end-users led to significant improvements in functionality and aesthetics. Beta testing involved 18 participants, including seven healthcare professionals, seven children and four parents. All participants successfully navigated the platform, completed tasks and interpreted PROM results. Participants described the platform as intuitive and child-friendly. Challenges included minor navigation issues on mobile devices. Suggestions for improvement included streamlined result visualisation and enhancements to the instructional material. Whilst parents and clinicians recognised the value of allowing parents to view their child's PROM results, considerations to ensure sensitivity were described.
Conclusion: The electronic PROM platform was successfully developed to support HRQoL assessment of children undergoing RT. Future research is needed to evaluate the feasibility, usability and acceptability in clinical practice.
{"title":"Development and Evaluation of an Electronic Patient-Reported Outcome Platform for Children Undergoing Radiation Therapy.","authors":"Mikaela Doig, Andrew Cunningham, Victoria Bedford, Hien Le, Matthew O'Connor, Sophie Jessop, Eva Bezak, Nayana Parange, Amanda Hutchinson, Peter Gorayski, Michala Short","doi":"10.1002/jmrs.70025","DOIUrl":"https://doi.org/10.1002/jmrs.70025","url":null,"abstract":"<p><strong>Introduction: </strong>Health-related quality of life (HRQoL) outcomes are not routinely collected in paediatric radiation therapy (RT). This study co-designed and evaluated an electronic platform to support routine HRQoL assessment using patient-reported outcome measures (PROMs).</p><p><strong>Methods: </strong>A digital platform was developed following a user-centred design approach. Development included planning with consumers and clinicians, identifying user needs through interviews and iterative design refinements. Alpha testing was performed with consumers. Beta testing involved directed tasks by children, parents and clinician participants to evaluate the developed platform. Thematic analysis of participant feedback was performed to identify refinements and shape clinical implementation strategies.</p><p><strong>Results: </strong>Iterative alpha testing with end-users led to significant improvements in functionality and aesthetics. Beta testing involved 18 participants, including seven healthcare professionals, seven children and four parents. All participants successfully navigated the platform, completed tasks and interpreted PROM results. Participants described the platform as intuitive and child-friendly. Challenges included minor navigation issues on mobile devices. Suggestions for improvement included streamlined result visualisation and enhancements to the instructional material. Whilst parents and clinicians recognised the value of allowing parents to view their child's PROM results, considerations to ensure sensitivity were described.</p><p><strong>Conclusion: </strong>The electronic PROM platform was successfully developed to support HRQoL assessment of children undergoing RT. Future research is needed to evaluate the feasibility, usability and acceptability in clinical practice.</p>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}