This retrospective planning study aimed to evaluate the role of bolus in achieving dose uniformity in the ankles and feet in paediatric patients undergoing Modulated Arc Total Body Irradiation (MATBI) treatment and to identify patient factors that may negate or warrant its use.
Methods
The clinically treated plans of 20 paediatric patients who received MATBI treatment utilising ankle and foot bolus (Bolus plan) were compared with two retrospectively generated plans; a plan with bolus removed and no re-optimisation (No Bolus plan), and a re-optimised plan without bolus attempting to achieve equal dosimetry to the clinical plan via monitor unit adjustment (MU plan). Descriptive statistics were used to evaluate the dose uniformity criteria of ±10% coverage of the reference dose (RD) for each subregion of the ankle and foot for the three plans. The impact of patient height, weight, and age at the time of treatment was evaluated using Spearman's correlation.
Results
Variation in doses >10% RD was minimal across the three plans, with an average D1cc difference < 0.4Gy. For the ankle and foot regions in the Bolus plans, the volume receiving at least 90% of the RD (V90) was on average > 92%. In No Bolus and MU plans, there was an average reduction of 24.5% and 23.2% V90 coverage respectively in the toes. Spearman's correlation suggests height has the strongest relationship to D1cc.
Conclusion
This study validated the continued use of ankle and foot bolus to achieve dosimetric goals for paediatric MATBI treatments, particularly V90 coverage across all heights.
{"title":"An evaluation of ankle and foot bolus in paediatric modulated arc total body irradiation (MATBI)","authors":"Hannah Hering BRadTherapy (Hons), Beth Effeney BAppSc (MRT-RT), MPH, Carole Brady BAppSc (MRT-RT), GCertHSC (Ed), MTrainDev (Rsch), Catriona Hargrave BAppSc (MRT-RT), MAppSc (Research), PhD","doi":"10.1002/jmrs.780","DOIUrl":"10.1002/jmrs.780","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>This retrospective planning study aimed to evaluate the role of bolus in achieving dose uniformity in the ankles and feet in paediatric patients undergoing Modulated Arc Total Body Irradiation (MATBI) treatment and to identify patient factors that may negate or warrant its use.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The clinically treated plans of 20 paediatric patients who received MATBI treatment utilising ankle and foot bolus (Bolus plan) were compared with two retrospectively generated plans; a plan with bolus removed and no re-optimisation (No Bolus plan), and a re-optimised plan without bolus attempting to achieve equal dosimetry to the clinical plan via monitor unit adjustment (MU plan). Descriptive statistics were used to evaluate the dose uniformity criteria of ±10% coverage of the reference dose (RD) for each subregion of the ankle and foot for the three plans. The impact of patient height, weight, and age at the time of treatment was evaluated using Spearman's correlation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Variation in doses >10% RD was minimal across the three plans, with an average D1cc difference < 0.4Gy. For the ankle and foot regions in the Bolus plans, the volume receiving at least 90% of the RD (V90) was on average > 92%. In No Bolus and MU plans, there was an average reduction of 24.5% and 23.2% V90 coverage respectively in the toes. Spearman's correlation suggests height has the strongest relationship to D1cc.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This study validated the continued use of ankle and foot bolus to achieve dosimetric goals for paediatric MATBI treatments, particularly V90 coverage across all heights.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":"71 3","pages":"355-364"},"PeriodicalIF":1.8,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jmrs.780","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140101792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yarema B. Bezchlibnyk MD, PhD, Rolando Quiles RT(R)(MR), Jeremy Barber BSc, Benjamin Osa BSME, Keven Clifford RT, Ryan Murtaugh MD, MBA
Introduction
Intracranial electroencephalography (iEEG) involves placing intracranial electrodes to localise seizures in patients with medically refractory epilepsy. While magnetic resonance imaging (MRI) enables visualisation of electrodes within patient-specific anatomy, the safety of these electrodes must be confirmed prior to routine clinical utilisation. Therefore, the purpose of this study was to evaluate the safety of iEEG electrodes from a particular manufacturer in a 3.0-Tesla (3.0T) MRI environment.
Methods
Measurements of magnetically induced displacement force and torque were determined for each of the 10 test articles using standardised techniques. Test articles were subsequently evaluated for radiofrequency-induced heating using a Perspex phantom in both open and ‘fault’ conditions. Additionally, we assessed radiofrequency (RF)-induced heating with all test articles placed into the phantom simultaneously to simulate an implantation, again in both open and ‘fault’ conditions. Finally, each test article was evaluated for MRI artefacts.
Results
The magnetically induced displacement force was found to be less than the force on the article due to gravity for all test articles. Similarly, the maximum magnetically induced torque was less than the worst-case torque due to gravity for all test articles apart from the 8-contact strip – for which it was 11% greater – and the depthalon cap. The maximum temperature change for any portion of any test article assessed individually was 1.7°C, or 1.2°C for any device component meant to be implanted intracranially. In the implantation configuration, the maximum recorded temperature change was 0.7°C.
Conclusions
MRI may be safely performed for localising iEEG electrodes at 3.0T under certain conditions.
{"title":"Safety of intracranial electrodes in an MRI environment: a technical report","authors":"Yarema B. Bezchlibnyk MD, PhD, Rolando Quiles RT(R)(MR), Jeremy Barber BSc, Benjamin Osa BSME, Keven Clifford RT, Ryan Murtaugh MD, MBA","doi":"10.1002/jmrs.775","DOIUrl":"10.1002/jmrs.775","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Intracranial electroencephalography (iEEG) involves placing intracranial electrodes to localise seizures in patients with medically refractory epilepsy. While magnetic resonance imaging (MRI) enables visualisation of electrodes within patient-specific anatomy, the safety of these electrodes must be confirmed prior to routine clinical utilisation. Therefore, the purpose of this study was to evaluate the safety of iEEG electrodes from a particular manufacturer in a 3.0-Tesla (3.0T) MRI environment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Measurements of magnetically induced displacement force and torque were determined for each of the 10 test articles using standardised techniques. Test articles were subsequently evaluated for radiofrequency-induced heating using a Perspex phantom in both open and ‘fault’ conditions. Additionally, we assessed radiofrequency (RF)-induced heating with all test articles placed into the phantom simultaneously to simulate an implantation, again in both open and ‘fault’ conditions. Finally, each test article was evaluated for MRI artefacts.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The magnetically induced displacement force was found to be less than the force on the article due to gravity for all test articles. Similarly, the maximum magnetically induced torque was less than the worst-case torque due to gravity for all test articles apart from the 8-contact strip – for which it was 11% greater – and the depthalon cap. The maximum temperature change for any portion of any test article assessed individually was 1.7°C, or 1.2°C for any device component meant to be implanted intracranially. In the implantation configuration, the maximum recorded temperature change was 0.7°C.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>MRI may be safely performed for localising iEEG electrodes at 3.0T under certain conditions.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":"71 3","pages":"461-473"},"PeriodicalIF":1.8,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jmrs.775","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140101793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad Reza Deevband PhD, Habib Mohammadi MSc, Yazdan Salimi PhD, Ahmad Mostaar PhD, Niloofar Deravi MD, Mobina Fathi MD, Kimia Vakili MD, Shirin Yaghoobpoor MD, Mehdi Ghorbani PhD, Abolhasan Divband MD, Meysam Tavakoli PhD
Introduction
Concerns regarding the adverse consequences of radiation have increased due to the expanded application of computed tomography (CT) in medical practice. Certain studies have indicated that the radiation dosage depends on the anatomical region, the imaging technique employed and patient-specific variables. The aim of this study is to present fitting models for the estimation of age-specific dose estimates (ASDE), in the same direction of size-specific dose estimates, and effective doses based on patient age, gender and the type of CT examination used in paediatric head, chest and abdomen–pelvis imaging.
Methods
A total of 583 paediatric patients were included in the study. Radiometric data were gathered from DICOM files. The patients were categorised into five distinct groups (under 15 years of age), and the effective dose, organ dose and ASDE were computed for the CT examinations involving the head, chest and abdomen–pelvis. Finally, the best fitting models were presented for estimation of ASDE and effective doses based on patient age, gender and the type of examination.
Results
The ASDE in head, chest, and abdomen–pelvis CT examinations increases with increasing age. As age increases, the effective dose in head and abdomen–pelvis CT scans decreased. However, for chest scans, the effective dose initially showed a decreasing trend until the first year of life; after that, it increases in correlation with age.
Conclusions
Based on the presented fitting model for the ASDE, these CT scan quantities depend on factors such as patient age and the type of CT examination. For the effective dose, the gender was also included in the fitting model. By utilising the information about the scan type, region and age, it becomes feasible to estimate the ASDE and effective dose using the models provided in this study.
{"title":"Introducing fitting models for estimating age-specific dose and effective dose in paediatric patients undergoing head, chest and abdomen–pelvis imaging protocols: a patient study","authors":"Mohammad Reza Deevband PhD, Habib Mohammadi MSc, Yazdan Salimi PhD, Ahmad Mostaar PhD, Niloofar Deravi MD, Mobina Fathi MD, Kimia Vakili MD, Shirin Yaghoobpoor MD, Mehdi Ghorbani PhD, Abolhasan Divband MD, Meysam Tavakoli PhD","doi":"10.1002/jmrs.772","DOIUrl":"10.1002/jmrs.772","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Concerns regarding the adverse consequences of radiation have increased due to the expanded application of computed tomography (CT) in medical practice. Certain studies have indicated that the radiation dosage depends on the anatomical region, the imaging technique employed and patient-specific variables. The aim of this study is to present fitting models for the estimation of age-specific dose estimates (ASDE), in the same direction of size-specific dose estimates, and effective doses based on patient age, gender and the type of CT examination used in paediatric head, chest and abdomen–pelvis imaging.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A total of 583 paediatric patients were included in the study. Radiometric data were gathered from DICOM files. The patients were categorised into five distinct groups (under 15 years of age), and the effective dose, organ dose and ASDE were computed for the CT examinations involving the head, chest and abdomen–pelvis. Finally, the best fitting models were presented for estimation of ASDE and effective doses based on patient age, gender and the type of examination.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The ASDE in head, chest, and abdomen–pelvis CT examinations increases with increasing age. As age increases, the effective dose in head and abdomen–pelvis CT scans decreased. However, for chest scans, the effective dose initially showed a decreasing trend until the first year of life; after that, it increases in correlation with age.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Based on the presented fitting model for the ASDE, these CT scan quantities depend on factors such as patient age and the type of CT examination. For the effective dose, the gender was also included in the fitting model. By utilising the information about the scan type, region and age, it becomes feasible to estimate the ASDE and effective dose using the models provided in this study.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":"71 2","pages":"251-260"},"PeriodicalIF":2.1,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jmrs.772","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140059644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Evidence-based medicine integrates clinical expertise, patient values and best research evidence in clinical decision-making. This study aimed to assess evidence-based medicine knowledge, attitudes, practices and associated factors among medical radiology technologists in Addis Ababa, Ethiopia.
Methods
A cross-sectional study was conducted among 392 medical radiology technologists from May to August 2022 using a self-administered questionnaire. Bivariate and multivariate logistic regression identified factors associated with evidence-based medicine practice.
Results
Most medical radiology technologists (57.7%) had moderate evidence-based medicine knowledge and 94.9% had favourable attitudes. However, 64.8% demonstrated poor evidence-based medicine practice. Factors significantly associated with better evidence-based medicine practice were moderate knowledge (AOR 1.949, 95% CI 1.155–3.291), good statistical understanding (AOR 1.824, 95% CI 1.135–2.930), sufficient time for evidence-based medicine (AOR 1.892, 95% CI 1.140–3.141), institutional support (AOR 2.093, 95% CI 1.271–3.440) and evidence-based medicine resource access (AOR 1.653, 95% CI 1.028–2.656).
Conclusion
Despite moderate knowledge and positive attitudes towards evidence-based medicine, most medical radiology technologists had suboptimal utilisation. Strategies to improve knowledge, ensure dedicated time, provide institutional support and resources could enhance evidence-based radiology practice.
导言：循证医学将临床专业知识、患者价值观和最佳研究证据整合到临床决策中。本研究旨在评估埃塞俄比亚亚的斯亚贝巴医疗放射技术人员的循证医学知识、态度、实践和相关因素：2022 年 5 月至 8 月，采用自填问卷的方式对 392 名放射医学技师进行了横断面研究。双变量和多变量逻辑回归确定了与循证医学实践相关的因素：大多数医学放射技师（57.7%）具有中等程度的循证医学知识，94.9%持积极态度。然而，64.8%的放射技术人员的循证医学实践较差。与更好的循证医学实践明显相关的因素有：中等程度的知识（AOR 1.949，95% CI 1.155-3.291）、良好的统计学理解（AOR 1.824，95% CI 1.135-2.930）、充足的循证医学时间（AOR 1.892，95% CI 1.140-3.141）、机构支持（AOR 2.093，95% CI 1.271-3.440）和循证医学资源获取（AOR 1.653，95% CI 1.028-2.656）：尽管大多数医学放射技术人员对循证医学有一定的了解并持积极态度，但他们对循证医学的利用率却不尽人意。提高知识水平、确保专用时间、提供机构支持和资源等策略可加强循证放射学实践。
{"title":"Competency in evidence-based medicine and associated factors among medical radiology technologists in Addis Ababa, Ethiopia","authors":"Girma Tufa Melesse MSc, Tewodros Amde MSc, Robel Tezera MSc, PhD fellow","doi":"10.1002/jmrs.777","DOIUrl":"10.1002/jmrs.777","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Evidence-based medicine integrates clinical expertise, patient values and best research evidence in clinical decision-making. This study aimed to assess evidence-based medicine knowledge, attitudes, practices and associated factors among medical radiology technologists in Addis Ababa, Ethiopia.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A cross-sectional study was conducted among 392 medical radiology technologists from May to August 2022 using a self-administered questionnaire. Bivariate and multivariate logistic regression identified factors associated with evidence-based medicine practice.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Most medical radiology technologists (57.7%) had moderate evidence-based medicine knowledge and 94.9% had favourable attitudes. However, 64.8% demonstrated poor evidence-based medicine practice. Factors significantly associated with better evidence-based medicine practice were moderate knowledge (AOR 1.949, 95% CI 1.155–3.291), good statistical understanding (AOR 1.824, 95% CI 1.135–2.930), sufficient time for evidence-based medicine (AOR 1.892, 95% CI 1.140–3.141), institutional support (AOR 2.093, 95% CI 1.271–3.440) and evidence-based medicine resource access (AOR 1.653, 95% CI 1.028–2.656).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Despite moderate knowledge and positive attitudes towards evidence-based medicine, most medical radiology technologists had suboptimal utilisation. Strategies to improve knowledge, ensure dedicated time, provide institutional support and resources could enhance evidence-based radiology practice.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":"71 3","pages":"344-354"},"PeriodicalIF":1.8,"publicationDate":"2024-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jmrs.777","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140039634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luisa E. Jacomina MD, Ryan Anthony F. Agas MD, Edward Christopher Dee MD, Pankaj Kumar Panda MSc, Michael Benedict A. Mejia MD
The burden of cancer in Asia Pacific, a region home to over four billion people, is growing. Because of sheer demographics alone, the Asia Pacific region arguably has the highest number of patients who can benefit from protons over conventional x-rays. However, only 39 out of 113 proton facilities globally are in Asia Pacific, and 11 of them are in low- and middle-income countries where 95% of the regional population reside. We draw attention to present resource distribution of proton therapy in Asia Pacific, highlight disparities in access, and suggest steps forward.
{"title":"Proton therapy in Asia Pacific: current resources, international disparities and steps forward","authors":"Luisa E. Jacomina MD, Ryan Anthony F. Agas MD, Edward Christopher Dee MD, Pankaj Kumar Panda MSc, Michael Benedict A. Mejia MD","doi":"10.1002/jmrs.776","DOIUrl":"10.1002/jmrs.776","url":null,"abstract":"<p>The burden of cancer in Asia Pacific, a region home to over four billion people, is growing. Because of sheer demographics alone, the Asia Pacific region arguably has the highest number of patients who can benefit from protons over conventional x-rays. However, only 39 out of 113 proton facilities globally are in Asia Pacific, and 11 of them are in low- and middle-income countries where 95% of the regional population reside. We draw attention to present resource distribution of proton therapy in Asia Pacific, highlight disparities in access, and suggest steps forward.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":"71 S2","pages":"6-9"},"PeriodicalIF":2.1,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jmrs.776","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139996524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maximise your CPD by reading the following selected article and answer the five questions. Please remember to self-claim your CPD and retain your supporting evidence. Answers will be available via the QR code and online at www.asmirt.org/news-and-publications/jmrs, as well as published in JMRS – Volume 71, Issue 4, December 2024.
Scan this QR code to find the answers, or visit www.asmirt.org/news-and-publications/jmrs
{"title":"Continuing Professional Development - Radiation Therapy","authors":"","doi":"10.1002/jmrs.770","DOIUrl":"10.1002/jmrs.770","url":null,"abstract":"<p>Maximise your CPD by reading the following selected article and answer the five questions. Please remember to self-claim your CPD and retain your supporting evidence. Answers will be available via the QR code and online at www.asmirt.org/news-and-publications/jmrs, as well as published in JMRS – Volume 71, Issue 4, December 2024.</p><p>Scan this QR code to find the answers, or visit www.asmirt.org/news-and-publications/jmrs</p>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":"71 S2","pages":"102"},"PeriodicalIF":2.1,"publicationDate":"2024-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jmrs.770","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139944217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Principles and Practice of Particle Therapy methodically compiles important concepts in particle therapy (PT) such as medical physics, radiobiology, treatment planning, image guidance, treatment delivery, advanced technologies, clinical indications and considerations for various anatomical disease sites. Undoubtably, this book is a clinically oriented resource providing a practical guide for radiation oncologists, medical physicists, radiation therapists and students who wish to learn about PT.
{"title":"Review of the Book Principles and Practice of Particle Therapy, Edited by Timothy D. Malouff and Daniel M. Trifiletti, 1st Edition111 River Street, Hoboken, NJ 07030, USA: John Wiley & Sons Ltd, 2022 p.560. ISBN: 9781119707516","authors":"Milad Mirzaei MRT, BBMedSc","doi":"10.1002/jmrs.763","DOIUrl":"10.1002/jmrs.763","url":null,"abstract":"<p>The <i>Principles and Practice of Particle Therapy</i> methodically compiles important concepts in particle therapy (PT) such as medical physics, radiobiology, treatment planning, image guidance, treatment delivery, advanced technologies, clinical indications and considerations for various anatomical disease sites. Undoubtably, this book is a clinically oriented resource providing a practical guide for radiation oncologists, medical physicists, radiation therapists and students who wish to learn about PT.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":"71 S2","pages":"99-100"},"PeriodicalIF":2.1,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jmrs.763","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140437954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Scott N. Penfold PhD, Alexandre M. C. Santos PhD, Melanie Penfold B MRS, Emma Shierlaw B MRS, Rosanna Crain B MRS
Introduction
Because of the co-location of critical organs at risk, base of skull tumours require steep dose gradients to achieve the prescribed dosimetric criteria. When available, proton beam therapy (PBT) is often considered a desirable modality for these cases, but in many instances, compromises in target coverage are still required to achieve critical organ at risk (OAR) tolerance doses. A number of techniques have been proposed to further improve the penumbra of PBT. In the current study, we propose a novel, collimator-free treatment planning technique that combines high-energy shoot-through proton beams with conventional Bragg peak spot placement. The small spot size of the high-energy pencil beams provides a sharp penumbra at the target boundary, and the Bragg peak spots provide a higher linear energy transfer (LET) boost to the target centre.
Methods
Three base of skull chordoma patients were retrospectively planned with three different PBT treatment planning techniques: (1) conventional intensity-modulated proton therapy (IMPT); (2) high-energy proton arc therapy (HE-PAT); and (3) the novel technique combining HE-PAT and IMPT, referred to as single high-energy arc with Bragg peak boost (SHARP). The Monaco 6 treatment planning system was used.
Results
SHARP was found to improve the PBT penumbra in the plane perpendicular to the HE-PAT beams. Minimal penumbra differences were observed in the plane of the HE-PAT beams. SHARP reduced dose-averaged LET to surrounding organs at risk.
Conclusion
A novel PBT treatment planning technique was successfully implemented. Initial results indicate the potential for SHARP to improve the penumbra of PBT treatments for base of skull tumours.
{"title":"Single high-energy arc proton therapy with Bragg peak boost (SHARP)","authors":"Scott N. Penfold PhD, Alexandre M. C. Santos PhD, Melanie Penfold B MRS, Emma Shierlaw B MRS, Rosanna Crain B MRS","doi":"10.1002/jmrs.769","DOIUrl":"10.1002/jmrs.769","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Because of the co-location of critical organs at risk, base of skull tumours require steep dose gradients to achieve the prescribed dosimetric criteria. When available, proton beam therapy (PBT) is often considered a desirable modality for these cases, but in many instances, compromises in target coverage are still required to achieve critical organ at risk (OAR) tolerance doses. A number of techniques have been proposed to further improve the penumbra of PBT. In the current study, we propose a novel, collimator-free treatment planning technique that combines high-energy shoot-through proton beams with conventional Bragg peak spot placement. The small spot size of the high-energy pencil beams provides a sharp penumbra at the target boundary, and the Bragg peak spots provide a higher linear energy transfer (LET) boost to the target centre.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Three base of skull chordoma patients were retrospectively planned with three different PBT treatment planning techniques: (1) conventional intensity-modulated proton therapy (IMPT); (2) high-energy proton arc therapy (HE-PAT); and (3) the novel technique combining HE-PAT and IMPT, referred to as single high-energy arc with Bragg peak boost (SHARP). The Monaco 6 treatment planning system was used.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>SHARP was found to improve the PBT penumbra in the plane perpendicular to the HE-PAT beams. Minimal penumbra differences were observed in the plane of the HE-PAT beams. SHARP reduced dose-averaged LET to surrounding organs at risk.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>A novel PBT treatment planning technique was successfully implemented. Initial results indicate the potential for SHARP to improve the penumbra of PBT treatments for base of skull tumours.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":"71 S2","pages":"27-36"},"PeriodicalIF":2.1,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jmrs.769","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139940064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maximise your CPD by reading the following selected article and answer the five questions. Please remember to self-claim your CPD and retain your supporting evidence. Answers will be available via the QR code and online at www.asmirt.org/news-and-publications/jmrs, as well as published in JMRS – Volume 71, Issue 4, December 2024.
Scan this QR code to find the answers, or visit www.asmirt.org/news-and-publications/jmrs
{"title":"Continuing Professional Development - Radiation Therapy","authors":"","doi":"10.1002/jmrs.771","DOIUrl":"10.1002/jmrs.771","url":null,"abstract":"<p>Maximise your CPD by reading the following selected article and answer the five questions. Please remember to self-claim your CPD and retain your supporting evidence. Answers will be available via the QR code and online at www.asmirt.org/news-and-publications/jmrs, as well as published in JMRS – Volume 71, Issue 4, December 2024.</p><p>Scan this QR code to find the answers, or visit www.asmirt.org/news-and-publications/jmrs</p>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":"71 S2","pages":"103"},"PeriodicalIF":2.1,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jmrs.771","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139912784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sally L. Ayesa MBBS, MSc(Medical Imaging), FRANZCR, FAANMS
As our understanding of genetics in cancer care improves, the role of personalised medicine for patients continues to grow. With the increasing emergence of novel technologies for patient assessment, such as the evaluation of circulating tumour DNA, we must reflect on the potentially changing role that medical imaging will play in the future of optimal patient care.
随着我们对癌症治疗中遗传学的理解不断加深，个性化医疗对患者的作用也在不断增强。随着用于患者评估的新型技术（如循环肿瘤 DNA 评估）的不断涌现，我们必须思考医学影像在未来最佳患者护理中可能扮演的不断变化的角色。
{"title":"Novel genetic assessments for cancer patients: where does medical imaging stand in the future of personalised medicine?","authors":"Sally L. Ayesa MBBS, MSc(Medical Imaging), FRANZCR, FAANMS","doi":"10.1002/jmrs.762","DOIUrl":"10.1002/jmrs.762","url":null,"abstract":"<p>As our understanding of genetics in cancer care improves, the role of personalised medicine for patients continues to grow. With the increasing emergence of novel technologies for patient assessment, such as the evaluation of circulating tumour DNA, we must reflect on the potentially changing role that medical imaging will play in the future of optimal patient care.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":"71 1","pages":"7-9"},"PeriodicalIF":2.1,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jmrs.762","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139735386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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