Flattled nose also called syphilis nose is a deformation of the nose due to the destruction of the cartilage of the nasal septum: the lower segment of the nose collapses, undergoing recoil and retract, becoming embedded in the upper segment. It is characteristic of congenital and tertiary syphilis [1]. We report the case of syphilitic aortitis revealed by flattened appearance of the nose.
{"title":"Clinical Dermatology Open Access Journal ISSN: 2574-7800 MEDWIN PUBLISHERS Committed to Create Value for ResearchersFlattned Nose Revealing Syphilitic Aortitis Clin Dermatol J Flattned Nose Revealing Syphilitic Aortitis","authors":"Z. Douhi","doi":"10.23880/cdoaj-16000296","DOIUrl":"https://doi.org/10.23880/cdoaj-16000296","url":null,"abstract":"Flattled nose also called syphilis nose is a deformation of the nose due to the destruction of the cartilage of the nasal septum: the lower segment of the nose collapses, undergoing recoil and retract, becoming embedded in the upper segment. It is characteristic of congenital and tertiary syphilis [1]. We report the case of syphilitic aortitis revealed by flattened appearance of the nose.","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127060386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Tuberous sclerosis (TS), a genetic multisystem disorder, is characterized by widespread hamartomas in multiple organs. The classic clinical symptoms consist of angiofibromas, epilepsy, and developmental delay. Dermatological change is one of the major features. Bilateral facial angiofibromas (FA), a common form of presentation, cause significant cosmetic, medical, and emotional problems. The emerging treatment for skin lesions is laser therapy. However, there is no report on the long-term outcome of combined use of ultra-pulse carbon dioxide (UPCD) laser and ablative fractional (AF) Er: YAG lasers to treat skin lesions in patients suffering TS. Methods: A retrospective study, conducted from March 2014 to July 2018, investigated 9 patients from the Northwest part of China who had TS treated with a sequential treatment of UPCD laser and AF Er: YAG laser. Results: The sequential use of the UPCD and AF Er: YAG laser is a safe and effective method for the treatment of FA in patients suffering TS with satisfactory long-term outcomes. Conclusions: The sequential use of the UPCD and AF Er: YAG laser is a safe and effective method for the treatment of FA in patients suffering TS with satisfactory long-term outcomes.
{"title":"Evaluating the Long-Term Outcome of the Ablative Lasers in the Treatment of Facial Angiofibromas in Tuberous Sclerosis: A TwoYear Follow-Up Study","authors":"L. Y","doi":"10.23880/cdoaj-16000239","DOIUrl":"https://doi.org/10.23880/cdoaj-16000239","url":null,"abstract":"Background: Tuberous sclerosis (TS), a genetic multisystem disorder, is characterized by widespread hamartomas in multiple organs. The classic clinical symptoms consist of angiofibromas, epilepsy, and developmental delay. Dermatological change is one of the major features. Bilateral facial angiofibromas (FA), a common form of presentation, cause significant cosmetic, medical, and emotional problems. The emerging treatment for skin lesions is laser therapy. However, there is no report on the long-term outcome of combined use of ultra-pulse carbon dioxide (UPCD) laser and ablative fractional (AF) Er: YAG lasers to treat skin lesions in patients suffering TS. Methods: A retrospective study, conducted from March 2014 to July 2018, investigated 9 patients from the Northwest part of China who had TS treated with a sequential treatment of UPCD laser and AF Er: YAG laser. Results: The sequential use of the UPCD and AF Er: YAG laser is a safe and effective method for the treatment of FA in patients suffering TS with satisfactory long-term outcomes. Conclusions: The sequential use of the UPCD and AF Er: YAG laser is a safe and effective method for the treatment of FA in patients suffering TS with satisfactory long-term outcomes.","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133796341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Observation on the Effect of Dermoscopy for Long-pulsed 1064nm Nd: YAG Laser in the Treatment of Onychomycosis","authors":"H. Cai","doi":"10.23880/cdoaj-16000277","DOIUrl":"https://doi.org/10.23880/cdoaj-16000277","url":null,"abstract":"","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129541207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recommendations for Cosmetology Procedures in the Chemotherapy – Induced Palmar-Plantar Erythrodysesthesia","authors":"Joanna Klonowska","doi":"10.23880/cdoaj-16000258","DOIUrl":"https://doi.org/10.23880/cdoaj-16000258","url":null,"abstract":"","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127179561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We report a case of allergic contact dermatitis caused by acrilates in a nail technician.
我们报告了一个由丙烯酸酯引起的过敏性接触性皮炎的病例。
{"title":"Acrylates: An Enemy of Nail Technicians","authors":"Aurora Gutiérrez González","doi":"10.23880/cdoaj-16000238","DOIUrl":"https://doi.org/10.23880/cdoaj-16000238","url":null,"abstract":"We report a case of allergic contact dermatitis caused by acrilates in a nail technician.","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127351290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The clinical course of leprosy varies depending on the level of host cell-mediated immunity to the causative agent, Mycobacterium leprae. In this study, the diagnostic aspects of the classification of the disease in five leprosy patients are presented alongside their clinical courses. The lepromatous leprosy (LL) Case presented with many erythematous plaques without anesthesia; pathology revealed the presence of abundant acid-fast bacilli (AFB). The patient developed reversal reactions during chemotherapy, and was diagnosed with subpolar LL. In this Case, resistance to three drugs was found. One borderline-tuberculoid (BT) leprosy Case had asymmetrically arranged multiple annular lesions, and another had one large erythematous lesion with small satellites. All these lesions were anesthetic, and the pathological findings revealed epithelioid granulomas; these clinicopathological findings are characteristic of BT leprosy. Another BT leprosy Case presented with neuralgia at the first visit, and on nerve biopsy, some nerve fascicles presented the feature of a reversal reaction. However, another nerve fascicle was found to be almost intact and showed positive staining in immunohistochemistry for M. leprae-specific phenolic-glycolipid I, although AFB were not found. In all three BT Cases, the slit-skin smears were negative. The borderline lepromatous (BL) leprosy Case involved numerous symmetric annular lesions with a characteristic punched-out feature. Loss of sensation was apparent in annular lesions. The smear tested positive, and abundant AFB were found inside the foamy Schwann cells. The differences in the clinical features of each patient reflect their immunity to the causative bacilli. In all, four Cases of the B-group were treated with the World Health Organization-recommended multibacillary regimen. One patient with BT leprosy developed anaphylactic shock against rifampicin (RFP). The monthly dose of RFP should therefore be administered following the direct observation procedure. The appropriate duration of chemotherapy for leprosy, especially in drug-resistant cases, should be studied further.
{"title":"Essential Aspects of Leprosy Classification and Clinical Course of Five Leprosy Patients, Including Four Relapsed Cases","authors":"N. M","doi":"10.23880/cdoaj-16000187","DOIUrl":"https://doi.org/10.23880/cdoaj-16000187","url":null,"abstract":"The clinical course of leprosy varies depending on the level of host cell-mediated immunity to the causative agent, Mycobacterium leprae. In this study, the diagnostic aspects of the classification of the disease in five leprosy patients are presented alongside their clinical courses. The lepromatous leprosy (LL) Case presented with many erythematous plaques without anesthesia; pathology revealed the presence of abundant acid-fast bacilli (AFB). The patient developed reversal reactions during chemotherapy, and was diagnosed with subpolar LL. In this Case, resistance to three drugs was found. One borderline-tuberculoid (BT) leprosy Case had asymmetrically arranged multiple annular lesions, and another had one large erythematous lesion with small satellites. All these lesions were anesthetic, and the pathological findings revealed epithelioid granulomas; these clinicopathological findings are characteristic of BT leprosy. Another BT leprosy Case presented with neuralgia at the first visit, and on nerve biopsy, some nerve fascicles presented the feature of a reversal reaction. However, another nerve fascicle was found to be almost intact and showed positive staining in immunohistochemistry for M. leprae-specific phenolic-glycolipid I, although AFB were not found. In all three BT Cases, the slit-skin smears were negative. The borderline lepromatous (BL) leprosy Case involved numerous symmetric annular lesions with a characteristic punched-out feature. Loss of sensation was apparent in annular lesions. The smear tested positive, and abundant AFB were found inside the foamy Schwann cells. The differences in the clinical features of each patient reflect their immunity to the causative bacilli. In all, four Cases of the B-group were treated with the World Health Organization-recommended multibacillary regimen. One patient with BT leprosy developed anaphylactic shock against rifampicin (RFP). The monthly dose of RFP should therefore be administered following the direct observation procedure. The appropriate duration of chemotherapy for leprosy, especially in drug-resistant cases, should be studied further.","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130622719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Homocysteine, a Biomarker of Cardiovascular Diseases, in Psoriasis–A Case Control Study","authors":"S. Gupta","doi":"10.23880/cdoaj-16000171","DOIUrl":"https://doi.org/10.23880/cdoaj-16000171","url":null,"abstract":"","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"387 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129275703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vulvar dermatoses are common problems in women and they are associated with significant morbidity. Their frequency and importance are often underestimated. In a prospective study we evaluated 200 adult females presenting vulvar symptoms and determined the spectrum and frequency of vulvar dermatoses in a Libyan population. Mean age was 38 years, 90% was married and 5% was pregnant ladies. The commonest condition was vulvovaginal candidiasis (22%) followed by genital warts (19%), bacterial infections (15%) contact dermatitis (11%), lichen simplex chronicus (8%) and other conditions. This study provided important data on the spectrum of vulvar dermatoses in Libyan adult patients and to the best of our knowledge it is the first study carried out on vulvar dermatoses in Libya.
{"title":"Vulvar Dermatoses in Libyan Adult Patients","authors":"S. Elfaituri","doi":"10.23880/CDOAJ-16000168","DOIUrl":"https://doi.org/10.23880/CDOAJ-16000168","url":null,"abstract":"Vulvar dermatoses are common problems in women and they are associated with significant morbidity. Their frequency and importance are often underestimated. In a prospective study we evaluated 200 adult females presenting vulvar symptoms and determined the spectrum and frequency of vulvar dermatoses in a Libyan population. Mean age was 38 years, 90% was married and 5% was pregnant ladies. The commonest condition was vulvovaginal candidiasis (22%) followed by genital warts (19%), bacterial infections (15%) contact dermatitis (11%), lichen simplex chronicus (8%) and other conditions. This study provided important data on the spectrum of vulvar dermatoses in Libyan adult patients and to the best of our knowledge it is the first study carried out on vulvar dermatoses in Libya.","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"233 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123871691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Facial Nodule in a Child, What you can think of?","authors":"Kassel Jihad","doi":"10.23880/cdoaj-16000267","DOIUrl":"https://doi.org/10.23880/cdoaj-16000267","url":null,"abstract":"","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114296952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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