{"title":"A Case of Palmoplantar Pustulosis and its Clinical Course under the Administration of Two Biological Products","authors":"M. Namisato","doi":"10.23880/cdoaj-16000281","DOIUrl":"https://doi.org/10.23880/cdoaj-16000281","url":null,"abstract":"","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115831302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Use of Dalmatian Tansy - Pyretrin - D and Mandelic Acid in the Care Supporting the Treatment of Rosacea Caused by Demodecosis","authors":"J. Igielska-Kalwat","doi":"10.23880/cdoaj-16000257","DOIUrl":"https://doi.org/10.23880/cdoaj-16000257","url":null,"abstract":"","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131635920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Rhinophyma is a benign skin condition which mostly affects Caucasian men between the ages of five and seven. It is characterized by progressively enlarging nasal skin, irregular thickening, and nodular deformation. This is the final stage of chronic acne rosacea. The main reasons patients seek medical attention are cosmetic and functional impairments, like nasal obstruction. In Rhinophyma, surgical removal of the hyperplastic tumor mass is recommended. We describe here the case of a giant Rhinophyma with respiratory and olfactory difficulties for 5 years
{"title":"Giant Rhinophyma: About a New Case","authors":"Imane Kacimi Alaoui","doi":"10.23880/cdoaj-16000298","DOIUrl":"https://doi.org/10.23880/cdoaj-16000298","url":null,"abstract":"The Rhinophyma is a benign skin condition which mostly affects Caucasian men between the ages of five and seven. It is characterized by progressively enlarging nasal skin, irregular thickening, and nodular deformation. This is the final stage of chronic acne rosacea. The main reasons patients seek medical attention are cosmetic and functional impairments, like nasal obstruction. In Rhinophyma, surgical removal of the hyperplastic tumor mass is recommended. We describe here the case of a giant Rhinophyma with respiratory and olfactory difficulties for 5 years","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122237525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Studies of the Risk Factors for HIV Transmission from Mothers Who are Seropositive under B+ Option to Children in the Mother- To-Child Transmission Prevention Sites of the City of Bangui","authors":"Lénguébanga Gabouga Falmata","doi":"10.23880/CDOAJ-16000177","DOIUrl":"https://doi.org/10.23880/CDOAJ-16000177","url":null,"abstract":"","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"34 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120887037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Socio-Demographic Profile of HIV-Positive Mothers under the B + Option Followed by Mother-To-Child Transmission Prevention Sites in Bangui City, Central African Republic","authors":"Lénguébanga Gabouga Falmata","doi":"10.23880/cdoaj-16000178","DOIUrl":"https://doi.org/10.23880/cdoaj-16000178","url":null,"abstract":"","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129972493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Palmo-plantar psoriasis (PPP) is highly debilitating and difficult to treat impairing quality of life of patients. Tildrakizumab is an anti-IL23p19 subunit monoclonal antibody approved for the treatment of moderate-severe chronic plaque psoriasis in adult candidates for systemic therapy. Objective of this study is to investigate the safety and efficacy of tildrakizumab in the management of palmo-plantar psoriasis. A total of 7 adults patients with moderate to severe PPP were retrospective analysed. Tildrakizumab 100 mg was administered at weeks 0, 4 and then every 12 weeks, by subcutaneous injection. Patients were visited at baseline, at week 16 and at week 28. Safety and efficacy were assessed at weeks 0, 16 and 28. Physician's Global Assessment (PGA) and Palmoplantar Pustular Psoriasis Area and Severity Index (PPPASI) clinical score were used to measure the efficacy. The mean PGA score was reduced from 3.6 at baseline to 1.7 after 16 weeks and 1.3 after 28 weeks. The mean PPPASI score was reduced from 19.2 at baseline to 9.2 after 16 weeks and 5.2 after 28 weeks. In conclusion tildrakizumab represents a safe and effective treatment for psoriasis even in difficult areas such as the palms and soles.
{"title":"Real-Life Effectiveness of Tildrakizumab in Chronic Palmo Plantar Psoriasis: A Case Series of 7 Patients with 28 weeks of Follow Up","authors":"Gaetano Licata","doi":"10.23880/cdoaj-16000299","DOIUrl":"https://doi.org/10.23880/cdoaj-16000299","url":null,"abstract":"Palmo-plantar psoriasis (PPP) is highly debilitating and difficult to treat impairing quality of life of patients. Tildrakizumab is an anti-IL23p19 subunit monoclonal antibody approved for the treatment of moderate-severe chronic plaque psoriasis in adult candidates for systemic therapy. Objective of this study is to investigate the safety and efficacy of tildrakizumab in the management of palmo-plantar psoriasis. A total of 7 adults patients with moderate to severe PPP were retrospective analysed. Tildrakizumab 100 mg was administered at weeks 0, 4 and then every 12 weeks, by subcutaneous injection. Patients were visited at baseline, at week 16 and at week 28. Safety and efficacy were assessed at weeks 0, 16 and 28. Physician's Global Assessment (PGA) and Palmoplantar Pustular Psoriasis Area and Severity Index (PPPASI) clinical score were used to measure the efficacy. The mean PGA score was reduced from 3.6 at baseline to 1.7 after 16 weeks and 1.3 after 28 weeks. The mean PPPASI score was reduced from 19.2 at baseline to 9.2 after 16 weeks and 5.2 after 28 weeks. In conclusion tildrakizumab represents a safe and effective treatment for psoriasis even in difficult areas such as the palms and soles.","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132170205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Toxic epidermal necrolysis (TEN)-like lesions have been described in the setting of lupus erythematosus, and have been considered as a specific hyperacute variant of cutaneous lupus erythematosus, with features different from classical drugrelated toxic epidermal necrolysis. This is a report of a case of subacute cutaneous lupus erythematosus in a 62-year old Caucasian woman, which evolved into a TEN-like presentation over the course of 4 weeks. The patient responded rapidly to treatment with high doses of prednisone
{"title":"Toxic Epidermal Necrolysis-like Subacute Cutaneous Lupus Erythematosus: A Case Report","authors":"Zivanovic D","doi":"10.23880/cdoaj-16000244","DOIUrl":"https://doi.org/10.23880/cdoaj-16000244","url":null,"abstract":"Toxic epidermal necrolysis (TEN)-like lesions have been described in the setting of lupus erythematosus, and have been considered as a specific hyperacute variant of cutaneous lupus erythematosus, with features different from classical drugrelated toxic epidermal necrolysis. This is a report of a case of subacute cutaneous lupus erythematosus in a 62-year old Caucasian woman, which evolved into a TEN-like presentation over the course of 4 weeks. The patient responded rapidly to treatment with high doses of prednisone","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"26 33","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132273746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Features of Emergency Remote Dermatological Care and Students Education in the Wartime","authors":"K. Kolyadenko","doi":"10.23880/cdoaj-16000278","DOIUrl":"https://doi.org/10.23880/cdoaj-16000278","url":null,"abstract":"","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132538008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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