H. Miyaji, Hiroyuki Yokoyama, Yuta Kosen, H. Nishimura, Kazuyasu Nakane, Saori Tanaka, Kaori Otani, Kana Inoue, Asako Ibara, Izumi Kanayama, Takashi Yoshida, Kosuke Ogawa, Erika Nishida, M. Kawanami
172 INTRODUCTION In tissue engineering therapy, proliferation and migration of regenerated cells should be facilitated to reform functional tissue following surgical treatment. For this objective, three-dimensional scaffolds, an important element of tissue engineering, are being extensively studied for application in regenerative procedures. Bioceramic materials have mechanical, biocompatible and osteoconductive properties for use as scaffolds in various artificially synthesized types and forms, e.g., bioactive glass , hydroxyapatite (HA) 2, , tricalcium phosphate (TCP) 3, 4 and composites 5, . β-TCP presents a greater biodegradable effect in comparison with HA . The β-TCP scaffold in combination with growth factors has been shown to Bone Augmentation in Rat by Highly Porous β-TCP Scaffolds with Different Open-cell Sizes in Combination with Fibroblast Growth Factor-2
{"title":"Bone augmentation in rat by highly porous β-TCP scaffolds with different open-cell sizes in combination with fibroblast growth factor-2","authors":"H. Miyaji, Hiroyuki Yokoyama, Yuta Kosen, H. Nishimura, Kazuyasu Nakane, Saori Tanaka, Kaori Otani, Kana Inoue, Asako Ibara, Izumi Kanayama, Takashi Yoshida, Kosuke Ogawa, Erika Nishida, M. Kawanami","doi":"10.11223/JARDE.10.172","DOIUrl":"https://doi.org/10.11223/JARDE.10.172","url":null,"abstract":"172 INTRODUCTION In tissue engineering therapy, proliferation and migration of regenerated cells should be facilitated to reform functional tissue following surgical treatment. For this objective, three-dimensional scaffolds, an important element of tissue engineering, are being extensively studied for application in regenerative procedures. Bioceramic materials have mechanical, biocompatible and osteoconductive properties for use as scaffolds in various artificially synthesized types and forms, e.g., bioactive glass , hydroxyapatite (HA) 2, , tricalcium phosphate (TCP) 3, 4 and composites 5, . β-TCP presents a greater biodegradable effect in comparison with HA . The β-TCP scaffold in combination with growth factors has been shown to Bone Augmentation in Rat by Highly Porous β-TCP Scaffolds with Different Open-cell Sizes in Combination with Fibroblast Growth Factor-2","PeriodicalId":16589,"journal":{"name":"Journal of oral tissue engineering","volume":"50 1","pages":"172-181"},"PeriodicalIF":0.0,"publicationDate":"2013-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80880876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of Akt on the Differentiation into Osteoclasts Caused by RANKL Stimulation","authors":"T. Kawasaki, S. Goda, N. Matsumoto","doi":"10.11223/JARDE.10.67","DOIUrl":"https://doi.org/10.11223/JARDE.10.67","url":null,"abstract":"","PeriodicalId":16589,"journal":{"name":"Journal of oral tissue engineering","volume":"47 1","pages":"67-76"},"PeriodicalIF":0.0,"publicationDate":"2013-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82156006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Masaki Fujii, M. Shiota, Kanako Noritake, Kazuhiro Kon, Hitoshi Sato, S. Kasugai
{"title":"Effect of Density of Hydroxyapatite Fiber Material on Bone Regeneration in Vertical Bone Augmentation Model","authors":"Masaki Fujii, M. Shiota, Kanako Noritake, Kazuhiro Kon, Hitoshi Sato, S. Kasugai","doi":"10.11223/JARDE.10.115","DOIUrl":"https://doi.org/10.11223/JARDE.10.115","url":null,"abstract":"","PeriodicalId":16589,"journal":{"name":"Journal of oral tissue engineering","volume":"19 1","pages":"115-122"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73354746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
9 INTRODUCTION Adiponectin / Acrp30 (adipocyte complement-related protein of 30 kDa), an adipose-derived hormone, exhibits various biological functions, such as regulating energy homeostasis, increasing insulin sensitivity in the liver and skeletal muscle, and protecting vascular walls from atherosclerosis 1, . Furthermore, recent studies suggest that adiponectin also plays important roles in bone metabolism. Adiponectin might act on bone formation through the autocrine / paracrine and endocrine pathways, and the indirect pathway by circulating adiponectin via enhancement of the insulin signaling . It could also increase bone mass by suppressing osteoclast differentiation and activity . We previously demonstrated the gene expression of adipocytokine receptors in murine pro-osteoblastic cells during osteoblastic differentiation, and indicated that adiponectin rather than leptin may be involved in osteoblastic differentiation . Acceleratory Effect of Novel Synthesized Collagen-like Peptide from Adiponectin on Osteoblastic Differentiation
{"title":"Acceleratory Effect of Novel Synthesized Collagen-like Peptide from Adiponectin on Osteoblastic Differentiation","authors":"J. Tanabe, A. Kamada, T. Ikeo","doi":"10.11223/JARDE.11.9","DOIUrl":"https://doi.org/10.11223/JARDE.11.9","url":null,"abstract":"9 INTRODUCTION Adiponectin / Acrp30 (adipocyte complement-related protein of 30 kDa), an adipose-derived hormone, exhibits various biological functions, such as regulating energy homeostasis, increasing insulin sensitivity in the liver and skeletal muscle, and protecting vascular walls from atherosclerosis 1, . Furthermore, recent studies suggest that adiponectin also plays important roles in bone metabolism. Adiponectin might act on bone formation through the autocrine / paracrine and endocrine pathways, and the indirect pathway by circulating adiponectin via enhancement of the insulin signaling . It could also increase bone mass by suppressing osteoclast differentiation and activity . We previously demonstrated the gene expression of adipocytokine receptors in murine pro-osteoblastic cells during osteoblastic differentiation, and indicated that adiponectin rather than leptin may be involved in osteoblastic differentiation . Acceleratory Effect of Novel Synthesized Collagen-like Peptide from Adiponectin on Osteoblastic Differentiation","PeriodicalId":16589,"journal":{"name":"Journal of oral tissue engineering","volume":"37 1","pages":"9-16"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79182886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Okeya, Masaki Asakura, T. Hayashi, Atsuko Ueno, M. Ito, Y. Ohno, T. Kawai, T. Noguchi
{"title":"Three-Dimensional Analysis and Longitudinal Observation for Osteoinductivity Induced by Bone Morphogenetic Protein","authors":"H. Okeya, Masaki Asakura, T. Hayashi, Atsuko Ueno, M. Ito, Y. Ohno, T. Kawai, T. Noguchi","doi":"10.11223/JARDE.11.1","DOIUrl":"https://doi.org/10.11223/JARDE.11.1","url":null,"abstract":"","PeriodicalId":16589,"journal":{"name":"Journal of oral tissue engineering","volume":"52 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91281747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jiefeng Cui, Yin‐kun Liu, Rena Matumoto, T. Uemura
{"title":"Highly Expression and Biological Function of Type VI Collagen on the Early Events of Chondrogenesis in Human Mesenchymal Stem Cells","authors":"Jiefeng Cui, Yin‐kun Liu, Rena Matumoto, T. Uemura","doi":"10.11223/JARDE.11.29","DOIUrl":"https://doi.org/10.11223/JARDE.11.29","url":null,"abstract":"","PeriodicalId":16589,"journal":{"name":"Journal of oral tissue engineering","volume":"AES-8 1","pages":"29-41"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84498491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Higa, Atsuko Ueno, T. Hayashi, Akiko Abe, Y. Ohno, T. Kawai, K. Kurita
{"title":"Utility of Prototype Porous Titanium as a Bone Regeneration Scaffold","authors":"T. Higa, Atsuko Ueno, T. Hayashi, Akiko Abe, Y. Ohno, T. Kawai, K. Kurita","doi":"10.11223/JARDE.10.163","DOIUrl":"https://doi.org/10.11223/JARDE.10.163","url":null,"abstract":"","PeriodicalId":16589,"journal":{"name":"Journal of oral tissue engineering","volume":"3 1","pages":"163-171"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86902887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Takayuki Sugimoto, Y. Yamazaki, K. Kumazawa, Yumiko Sone, A. Takeda, E. Uchinuma
103 INTRODUCTION Cleft lip/cleft palate (CL/CP) is a congenital abnormality that occurs in approximately 1 in every 500 Japanese infants. Affected patients require multiple surgical procedures with different objectives such as gain-of-function and cosmetic improvement. An important element of treatment for CL/CP is the attainment of normal occlusion. This requires bone formation in the defects of the alveolar cleft along with proper tooth The Significance of Performing Osteogenic Differentiation in Human Bone Tissue-Derived Mesenchymal Stromal Cells
{"title":"The Significance of Performing Osteogenic Differentiation in Human Bone Tissue-Derived Mesenchymal Stromal Cells","authors":"Takayuki Sugimoto, Y. Yamazaki, K. Kumazawa, Yumiko Sone, A. Takeda, E. Uchinuma","doi":"10.11223/JARDE.11.103","DOIUrl":"https://doi.org/10.11223/JARDE.11.103","url":null,"abstract":"103 INTRODUCTION Cleft lip/cleft palate (CL/CP) is a congenital abnormality that occurs in approximately 1 in every 500 Japanese infants. Affected patients require multiple surgical procedures with different objectives such as gain-of-function and cosmetic improvement. An important element of treatment for CL/CP is the attainment of normal occlusion. This requires bone formation in the defects of the alveolar cleft along with proper tooth The Significance of Performing Osteogenic Differentiation in Human Bone Tissue-Derived Mesenchymal Stromal Cells","PeriodicalId":16589,"journal":{"name":"Journal of oral tissue engineering","volume":"31 1","pages":"103-112"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87899723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Imai, Kazuaki Nakamura, A. Tanoue, K. Suese, Y. Honda, Fumiya Ogawa, Chiaki Watanabe, H. Ohmukai, H. Takashima
{"title":"Development of the Embryotoxicity Test using the Hybrid 3D Cultivation Technique of Human Hepatocytes and a Mouse ES cells - Use of Novel Feeder","authors":"K. Imai, Kazuaki Nakamura, A. Tanoue, K. Suese, Y. Honda, Fumiya Ogawa, Chiaki Watanabe, H. Ohmukai, H. Takashima","doi":"10.11223/JARDE.11.51","DOIUrl":"https://doi.org/10.11223/JARDE.11.51","url":null,"abstract":"","PeriodicalId":16589,"journal":{"name":"Journal of oral tissue engineering","volume":"130 1","pages":"51-56"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73148018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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