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Journal of oral tissue engineering最新文献

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Embryotoxic Potential of the Dental Adhesives by the Cell Differentiation Culture with the Embryonic Stem Cell Test 细胞分化培养与胚胎干细胞试验对牙胶粘剂胚胎毒性的影响
Pub Date : 2013-01-01 DOI: 10.11223/JARDE.11.148
K. Imai, T. Nishikawa, Tomoharu Okamura, A. Tanaka, K. Suese, Y. Honda, H. Sawai, H. Takashima
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引用次数: 7
Expression of MicroRNAs in the Extracellular Microvesicles of Murine Osteoclasts 小鼠破骨细胞胞外微泡中microrna的表达
Pub Date : 2013-01-01 DOI: 10.11223/JARDE.10.142
T. Kagiya, M. Taira
142 INTRODUCTION Bone is one of the most important oral tissues. It is maintained by the balance between bone formation and resorption . It is remodeled continuously by two specialized cell types: bone-forming osteoblasts and bone-resorbing osteoclasts . Osteoclasts are tartrate-resistant acid phosphatase (TRAP)-positive, multinucleated giant cells that originate from the monocyte/macrophage lineage of hematopoietic stem cells . Stromal cells and osteoblasts express macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor-κB ligand (RANKL), which are essential for the induction of osteoclasts. In terms of tissue engineering, osteoclasts and macrophages resorb scaffolds, making space for bone matrix formation . Consequently, osteoclasts play an important role in bone regeneration. We reported previously microRNAs (miRNAs) expression profiles during osteoclastogenesis using microarrays . miRNAs are small, endogenous, noncoding RNAs of approximately 22 nuExpression of MicroRNAs in the Extracellular Microvesicles of Murine Osteoclasts
骨是口腔最重要的组织之一。它是由骨形成和骨吸收之间的平衡维持的。它由两种特殊的细胞类型不断地重塑:成骨细胞和骨吸收破骨细胞。破骨细胞是酒石酸抗性酸性磷酸酶(TRAP)阳性的多核巨细胞,起源于造血干细胞的单核/巨噬细胞谱系。基质细胞和成骨细胞表达巨噬细胞集落刺激因子(M-CSF)和核因子-κB配体受体激活因子(RANKL),它们对破骨细胞的诱导至关重要。在组织工程中,破骨细胞和巨噬细胞吸收支架,为骨基质的形成提供空间。因此,破骨细胞在骨再生中起重要作用。我们以前报道过microRNAs (miRNAs)表达谱在破骨细胞形成过程中使用微阵列。mirna是一种小的、内源性的、非编码的rna,大约有22种,在小鼠破骨细胞的细胞外微泡中表达
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引用次数: 6
Bone Response of Collagen- or Laminin-immobilized Screw-type Titanium Implants using Tresyl Chloride-activated Technique 三酰氯活化技术固定化胶原或层粘胶蛋白螺钉型钛种植体的骨反应
Pub Date : 2013-01-01 DOI: 10.11223/JARDE.11.113
Yuki Raita, K. Komatsu, T. Hayakawa
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引用次数: 2
Matrix Metalloproteinase-1 Produced by Human CXCL8 - Activated NK Cells 人CXCL8活化NK细胞产生基质金属蛋白酶-1
Pub Date : 2013-01-01 DOI: 10.11223/JARDE.11.163
S. Goda, H. Inoue, Eisuke Domae, Makiko Kagawa, Yukiko Hosoyama, N. Matsumoto, Y. Nishikawa, T. Ikeo
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引用次数: 0
Effects of Calcium Carbonate on Odontoblast Differentiation and Calcification Ability of Human Dental Pulp Cells 碳酸钙对人牙髓细胞成牙体分化及钙化能力的影响
Pub Date : 2013-01-01 DOI: 10.11223/JARDE.11.123
S. Hirayama, C. Komine, C. Takahashi, Satoshi Matsui, K. Matsushima
123 INTRODUCTION Understanding the biology of the dentin-pulp complex has now reached the point at which new treatment modalities aimed at tooth regeneration might be realized in clinical settings. Pulp capping is best described as capping of the exposed pulp and is indicated for reversible pulp tissue injury after physical or mechanical trauma in developing or mature teeth. The control of infection and biocompatibility of pulp-capping materials are important factors in determining treatment outcomes . Typically, agents based on calcium hydroxide (Ca(OH)2) and mineral trioxide aggregate (MTA) are used for direct pulp-capping treatment. Ca(OH)2 dissociates into calcium and hydroxyl ions, which, in turn, results in an increase in pH from neutrality to 12.5 and the release of calcium ions . This high pH resulting from the dissociation of Ca(OH)2 is thought to produce an enviEffects of Calcium Carbonate on Odontoblast Differentiation and Calcification Ability of Human Dental Pulp Cells
对牙本质-牙髓复合体生物学的理解已经达到了在临床环境中实现牙齿再生的新治疗方式的地步。牙髓盖复盖是对外露牙髓的盖复盖,适用于发育或成熟牙齿的物理或机械创伤后的可逆性牙髓组织损伤。感染的控制和盖髓材料的生物相容性是决定治疗效果的重要因素。通常,基于氢氧化钙(Ca(OH)2)和矿物三氧化物骨料(MTA)的药剂用于直接盖浆处理。Ca(OH)2解离成钙离子和羟基离子,这反过来又导致pH从中性增加到12.5,并释放钙离子。这种由Ca(OH)2解离产生的高pH值被认为是碳酸钙对人牙髓细胞成牙细胞分化和钙化能力的影响
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引用次数: 2
Comparative Analysis of Efficacy of Ozone Nano Bubble Water (NBW3) with Established Antimicrobials. Bactericidal Efficacy and Cellular Response. An in Vitro Study 臭氧纳米泡水(NBW3)与现有抗菌剂的效果对比分析。杀菌效果和细胞反应。体外研究
Pub Date : 2013-01-01 DOI: 10.11223/JARDE.10.131
Akiko Furuichi, S. Arakawa, Y. Mano, I. Morita, N. Tachikawa, Yu-ichi Yamada, S. Kasugai
13
13
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引用次数: 5
Low-energy Laser Irradiation Induces the Expression of Osteopontin in Tension Side during Orthodontic Tooth Movement 低能激光照射诱导正畸牙齿运动时张力侧骨桥蛋白的表达
Pub Date : 2013-01-01 DOI: 10.11223/JARDE.11.67
Mizuho Ohashi, M. Yamaguchi, Y. Tanimoto, K. Kasai
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引用次数: 1
Angiogenesis of Metal Ions by Components of Dental Gold-silver-palladium Alloys used by Dental Prosthetics in Vitro 口腔修复体用金银钯合金成分对金属离子血管生成的影响
Pub Date : 2013-01-01 DOI: 10.11223/JARDE.11.79
K. Imai, K. Suese, Y. Honda, H. Takashima
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引用次数: 1
Erratum to: Evaluation of Bone Regeneration using Platelet-rich or Platelet-poor Plasma Combined with Autologous Mesenchymal Stem Cells 评估富血小板或贫血小板血浆联合自体间充质干细胞的骨再生效果
Pub Date : 2013-01-01 DOI: 10.11223/JARDE.11.57
Kenichirou Yasui, Yoshiyuki Arima, Peiqi Li, Tomoko Tokuda, Eiko Azumi, Aki Nishiura, Tomohiko Ito, Y. Hashimoto, Naoya Uemura, S. Baba, N. Matsumoto
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引用次数: 0
Effect of VCAM-1 on the Differentiation into Osteoclast VCAM-1对破骨细胞分化的影响
Pub Date : 2013-01-01 DOI: 10.11223/JARDE.11.154
H. Hayashi, Yosuke Ujii, S. Goda, N. Matsumoto
154 INTRODUCTION Tooth movement in orthodontic therapy is the result in the two events comprising bone remodeling; bone formation by osteoblasts and bone resorption by osteoclasts. Both processes are synchronized by interand intracellular signaling involving hormones, growth factors, and attachment receptors binding to the extracellular matrix (ECM). ECM is gradually increased in the pressure side and reduced in the tension side in orthodontic therapy . Integrins are transmembrane glycoproteins consisting of α and β chains, and there are eight subfamilies and there are eight subfamilies based on β-chain structure, β1 to β8. VLA-4 (very late antigen: α4β1) and VLA-5 (very late antigen: α5β1) play the most central role in the adhesion between T cells and vascular endothelial cells . The extracellular matrix protein, VCAM-1 is a member of the transmembrane immunoglobulin superfamily . Proteolytic shedding of VCAM-1 also generates a soluble form of VCAM-1 . The predominant receptor for VCAM-1 is integrin α4β1, which is expressed by many cell types of the hematopoietic lineage, including B and T lymphocytes, Effect of VCAM-1 on the Differentiation into Osteoclast
正畸治疗中的牙齿移动是两个事件的结果:骨重塑;成骨细胞的骨形成和破骨细胞的骨吸收。这两个过程都是通过细胞间和细胞内的信号传导同步进行的,包括激素、生长因子和与细胞外基质(ECM)结合的附着受体。在正畸治疗中,ECM在压力侧逐渐增加,在张力侧逐渐减少。整合素是由α链和β链组成的跨膜糖蛋白,有8个亚家族,根据β链结构分为β1 ~ β8 8个亚家族。在T细胞与血管内皮细胞的粘附过程中,VLA-4(极迟抗原:α4β1)和VLA-5(极迟抗原:α5β1)起着最核心的作用。细胞外基质蛋白VCAM-1是跨膜免疫球蛋白超家族的成员。VCAM-1的蛋白水解脱落也产生可溶形式的VCAM-1。VCAM-1的主要受体是整合素α4β1,在多种造血细胞类型中均有表达,包括B淋巴细胞和T淋巴细胞
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引用次数: 1
期刊
Journal of oral tissue engineering
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