Pub Date : 1900-01-01DOI: 10.51737/2766-4813.2022.050
M. K, B. H, Hayashi K, Dohi A, K. A
Recent pharmacological topic for diabetes includes clinical application of Glucagon-like peptide 1 receptor agonists (GLP-1 RAs). Among them, oral semaglutide (Rybelsus) has been developed as the first oral form of GLP-1RA by useful application of sodium N-(8-[2-hydroxybenzoyl] amino) caprylate (SNAC). Semaglutide concentration in the blood was compared when fasting time period after Rybelsus administration would be 15, 30, 60 and 120 minutes. As a result, the concentration ratio after 4 hours was 1.00, 1.67, 2.60 and 3.06, respectively. Authors have experienced a diabetic case of remarkable efficacy as HbA1c -1.4% and weight -5kg, who kept 3-4 hours fasting after Rybelsus intake.
{"title":"Longer Fasting After Rybelsus Administration Contributes Higher Efficacy","authors":"M. K, B. H, Hayashi K, Dohi A, K. A","doi":"10.51737/2766-4813.2022.050","DOIUrl":"https://doi.org/10.51737/2766-4813.2022.050","url":null,"abstract":"Recent pharmacological topic for diabetes includes clinical application of Glucagon-like peptide 1 receptor agonists (GLP-1 RAs). Among them, oral semaglutide (Rybelsus) has been developed as the first oral form of GLP-1RA by useful application of sodium N-(8-[2-hydroxybenzoyl] amino) caprylate (SNAC). Semaglutide concentration in the blood was compared when fasting time period after Rybelsus administration would be 15, 30, 60 and 120 minutes. As a result, the concentration ratio after 4 hours was 1.00, 1.67, 2.60 and 3.06, respectively. Authors have experienced a diabetic case of remarkable efficacy as HbA1c -1.4% and weight -5kg, who kept 3-4 hours fasting after Rybelsus intake.","PeriodicalId":166084,"journal":{"name":"SunText Review of Medical & Clinical Research","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125296234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.51737/2766-4813.2022.058
Alharbi H, A. F., M. A., Alhumaidan N, Ali Bi
Background: Gastrointestinal stromal tumor (GIST) is considered a rare disease entity, accounting for less than 3% of all gastrointestinal neoplasms, but by far considered the most common primary mesenchymal tumors of the gastrointestinal system. It’s sporadic more than in neoplastic syndromes and can be found anywhere along the GI system but the stomach is considered the most common site. Unless the tumor is unrespectable or metastatic, surgery is the mainstay of treatment Method: Medical records of all patients diagnosed with GIST in Prince Sultan Military Medical City located in Riyadh the capital of Saudi Arabia in the time between January 2015 and December 2020 were collected, including patients' age, gender, clinical presentations, radiological investigations and features, histopathological findings and Immunohistochemically markers. Results: A 39 cases found, with 19 males and 20 females. All were Saudi with majority of patients which was 23 (59%) were diagnosed between the age of 40 and 60 years. Most common location was stomach 22 (56.4%), followed by 8 (20.5%) cases in small bowl. Using NIH criteria for GIST risk assessment for malignant behaviour, we stratified our cases into high, intermediate, low, and very low risk (28.2%, 10.2%, 33.3%, and 20.5% respectively). Conclusion: This retrospective review confirms multiple GIST features that correlate closely with other published studies. Further prospective studies needed with higher sample size and unified parameters for better understanding of GIST tumors features, management, and prognosis.
{"title":"Gastrointestinal Stromal Tumors in a Tertiary Center in Saudi Arabia","authors":"Alharbi H, A. F., M. A., Alhumaidan N, Ali Bi","doi":"10.51737/2766-4813.2022.058","DOIUrl":"https://doi.org/10.51737/2766-4813.2022.058","url":null,"abstract":"Background: Gastrointestinal stromal tumor (GIST) is considered a rare disease entity, accounting for less than 3% of all gastrointestinal neoplasms, but by far considered the most common primary mesenchymal tumors of the gastrointestinal system. It’s sporadic more than in neoplastic syndromes and can be found anywhere along the GI system but the stomach is considered the most common site. Unless the tumor is unrespectable or metastatic, surgery is the mainstay of treatment Method: Medical records of all patients diagnosed with GIST in Prince Sultan Military Medical City located in Riyadh the capital of Saudi Arabia in the time between January 2015 and December 2020 were collected, including patients' age, gender, clinical presentations, radiological investigations and features, histopathological findings and Immunohistochemically markers. Results: A 39 cases found, with 19 males and 20 females. All were Saudi with majority of patients which was 23 (59%) were diagnosed between the age of 40 and 60 years. Most common location was stomach 22 (56.4%), followed by 8 (20.5%) cases in small bowl. Using NIH criteria for GIST risk assessment for malignant behaviour, we stratified our cases into high, intermediate, low, and very low risk (28.2%, 10.2%, 33.3%, and 20.5% respectively). Conclusion: This retrospective review confirms multiple GIST features that correlate closely with other published studies. Further prospective studies needed with higher sample size and unified parameters for better understanding of GIST tumors features, management, and prognosis.","PeriodicalId":166084,"journal":{"name":"SunText Review of Medical & Clinical Research","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116685965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.51737/2766-4813.2022.046
F. G, Bucchieri S, Rossi D, D. D., C. G., Todaro B, Picone G, S. P
{"title":"Ambulatory Blood Pressure Monitoring or Self Pressure Evaluation: What’s Better?","authors":"F. G, Bucchieri S, Rossi D, D. D., C. G., Todaro B, Picone G, S. P","doi":"10.51737/2766-4813.2022.046","DOIUrl":"https://doi.org/10.51737/2766-4813.2022.046","url":null,"abstract":"","PeriodicalId":166084,"journal":{"name":"SunText Review of Medical & Clinical Research","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131886799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.51737/2766-4813.2023.082
M. S, U. A, H. S.
{"title":"Recurrent Planter Fasciitis as First Extraintestinal Manifestation of Inflammatory Bowel Disease [Crohn's Disease]","authors":"M. S, U. A, H. S.","doi":"10.51737/2766-4813.2023.082","DOIUrl":"https://doi.org/10.51737/2766-4813.2023.082","url":null,"abstract":"","PeriodicalId":166084,"journal":{"name":"SunText Review of Medical & Clinical Research","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123639582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.51737/2766-4813.2022.063
Y. T, Oklar M, Talan M, Kardas G
Purpose: To evaluate the etiological factors that cause end-stage eye disease or phthisis bulbi requiring enucleation or evisceration and our surgical results. Material and Methods: Medical records of 226 patients, who underwent eye removal surgery, were analyzed retrospectively. Demographic information, clinical history, surgical procedure and histopathological data were all collected. Evisceration surgery was performed under general anesthesia in all patients except tumor cases and one patient with rhino-orbital mucormycosis. The patients were followed for an average of 16.46 ± 10.78 months and checked for the possible complications, cosmetic and functional results. Results: A 144 men, and 82 women, with a mean age of 41.78 ± 22.6 years, were underwent nucleation (n=15) or evisceration (n=211) due to traumatic (n=169) and non-traumatic (n=57) causes. In the traumatic group, 79.8% of 169 patients were injured by penetrating and 14.2% by blunt trauma. A 3.6% of the patients were injured in a traffic accident, and 2.4% of them were injured by explosives. In the non-traumatic group, 40% of 25 patients had post-traumatic endophalmitis, 32% had endophthalmitis due to corneal ulceration and melting, 24% had endophthalmitis after cataract surgery. One patient had panophthalmitis due to rhino-orbital mucormycosis. Another cause in the non-traumatic group was glaucoma, of which 92.3% had neovascular glaucoma and 8.7% had congenital glaucoma. Of the patients who were enucleated for tumor, 35.7% had retinoblastoma, 14.3% had medulloepithelioma, 42.9% had uveal melanoma and 7.1% had metastastatic tumor from paranasal sinuses. The most common complaint in the follow-up period was discharge, seen in all prosthesis wearing patients. 13.3% of the patients had itching due to ocular prosthesis. 4.4% of the patients were complaining about deep superior sulcus. 4.4% had pyogenic granuloma and 17.8% had implant exposure. Conclusion: Etiological factors should be carefully evaluated and precautions should take in order to reduce devastating effect of the physical loss of the eye.
{"title":"Common Causes of Eye Removal Surgery in Turkish Patients: A Review of 226 Cases","authors":"Y. T, Oklar M, Talan M, Kardas G","doi":"10.51737/2766-4813.2022.063","DOIUrl":"https://doi.org/10.51737/2766-4813.2022.063","url":null,"abstract":"Purpose: To evaluate the etiological factors that cause end-stage eye disease or phthisis bulbi requiring enucleation or evisceration and our surgical results. Material and Methods: Medical records of 226 patients, who underwent eye removal surgery, were analyzed retrospectively. Demographic information, clinical history, surgical procedure and histopathological data were all collected. Evisceration surgery was performed under general anesthesia in all patients except tumor cases and one patient with rhino-orbital mucormycosis. The patients were followed for an average of 16.46 ± 10.78 months and checked for the possible complications, cosmetic and functional results. Results: A 144 men, and 82 women, with a mean age of 41.78 ± 22.6 years, were underwent nucleation (n=15) or evisceration (n=211) due to traumatic (n=169) and non-traumatic (n=57) causes. In the traumatic group, 79.8% of 169 patients were injured by penetrating and 14.2% by blunt trauma. A 3.6% of the patients were injured in a traffic accident, and 2.4% of them were injured by explosives. In the non-traumatic group, 40% of 25 patients had post-traumatic endophalmitis, 32% had endophthalmitis due to corneal ulceration and melting, 24% had endophthalmitis after cataract surgery. One patient had panophthalmitis due to rhino-orbital mucormycosis. Another cause in the non-traumatic group was glaucoma, of which 92.3% had neovascular glaucoma and 8.7% had congenital glaucoma. Of the patients who were enucleated for tumor, 35.7% had retinoblastoma, 14.3% had medulloepithelioma, 42.9% had uveal melanoma and 7.1% had metastastatic tumor from paranasal sinuses. The most common complaint in the follow-up period was discharge, seen in all prosthesis wearing patients. 13.3% of the patients had itching due to ocular prosthesis. 4.4% of the patients were complaining about deep superior sulcus. 4.4% had pyogenic granuloma and 17.8% had implant exposure. Conclusion: Etiological factors should be carefully evaluated and precautions should take in order to reduce devastating effect of the physical loss of the eye.","PeriodicalId":166084,"journal":{"name":"SunText Review of Medical & Clinical Research","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125298884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.51737/2766-4813.2023.080
Zaman F, Akhtar S, Fatema B, B. M
{"title":"Profile of Wound Infection Following Caesarean Delivery at Institute of Child & Mother Health, Matuail, Dhaka","authors":"Zaman F, Akhtar S, Fatema B, B. M","doi":"10.51737/2766-4813.2023.080","DOIUrl":"https://doi.org/10.51737/2766-4813.2023.080","url":null,"abstract":"","PeriodicalId":166084,"journal":{"name":"SunText Review of Medical & Clinical Research","volume":"134 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134542792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.51737/2766-4813.2023.073
Snoussi M, Belmekki A
{"title":"Thrombotic Microangiopathy in a Patient with Systemic Lupus Erythematosus","authors":"Snoussi M, Belmekki A","doi":"10.51737/2766-4813.2023.073","DOIUrl":"https://doi.org/10.51737/2766-4813.2023.073","url":null,"abstract":"","PeriodicalId":166084,"journal":{"name":"SunText Review of Medical & Clinical Research","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114711726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.51737/2766-4813.2022.061
Yamashita H, B. H, Kato Y, Ogura K, Sueki E
{"title":"Clinical Improvement of Weight, HbA1c and Liver Function by Rybelsus (Oral Semaglutide) In Patient with Type 2 Diabetes (T2D), Obesity and Fatty Liver","authors":"Yamashita H, B. H, Kato Y, Ogura K, Sueki E","doi":"10.51737/2766-4813.2022.061","DOIUrl":"https://doi.org/10.51737/2766-4813.2022.061","url":null,"abstract":"","PeriodicalId":166084,"journal":{"name":"SunText Review of Medical & Clinical Research","volume":"86 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129182348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.51737/2766-4813.2022.064
P. M.
{"title":"Omicron Variant: Similar or Different Than Other Sars-Cov-2 Variants? Along With Significance of Nanomaterial in Omicron","authors":"P. M.","doi":"10.51737/2766-4813.2022.064","DOIUrl":"https://doi.org/10.51737/2766-4813.2022.064","url":null,"abstract":"","PeriodicalId":166084,"journal":{"name":"SunText Review of Medical & Clinical Research","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130365411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.51737/2766-4813.2022.051
R. N, K. A., Rafia R, M. S., Amin A, A. S., Islam Ms, Hosen A
{"title":"Comparative Study of Nutritional Compounds and Microbial Analysis of Moringa Oleifera (Sajna Leaf) Powder in Different Drying Method during Storage Periods","authors":"R. N, K. A., Rafia R, M. S., Amin A, A. S., Islam Ms, Hosen A","doi":"10.51737/2766-4813.2022.051","DOIUrl":"https://doi.org/10.51737/2766-4813.2022.051","url":null,"abstract":"","PeriodicalId":166084,"journal":{"name":"SunText Review of Medical & Clinical Research","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132268408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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