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A diagnostic model based on clinical indicators and radiomics features for superior labral anterior and posterior lesions in the shoulder joint. 基于临床指标和放射组学特征的上唇肩关节前后病变诊断模型。
IF 1.6 4区 医学 Pub Date : 2026-01-01 Epub Date: 2026-01-25 DOI: 10.1177/10225536261418429
Hongyu Wang, Lin Wang, Lei Shi, Fei Wang, Guanghan Gao, Qingyun Xue

BackgroundSuperior labrum anterior and posterior (SLAP) lesions are a common cause of shoulder pain and instability. Accurate diagnosis remains challenging in clinical practice. This study aims to develop and evaluate radiomics models and combined models integrating radiomics and clinical features for SLAP lesion detection.MethodsThis retrospective study included 149 patients who underwent shoulder arthroscopic surgery with preoperative shoulder magnetic resonance imaging (MRI) between 2019 and 2024. Regions of interest (ROIs) were manually delineated on MRI oblique coronal proton density-weighted fat-suppressed (PD FS) images, and radiomics features were subsequently extracted from these defined regions. Feature selection employed independent t-tests, Mann-Whitney U tests, Pearson correlation analysis, and least absolute shrinkage and selection operator (LASSO) regression. Common machine learning models including Support Vector Machine (SVM), Random Forest (RF), and Light Gradient Boosting Machine (LightGBM) were employed to construct diagnostic models based on radiomics features. A combined model integrating radiomics and clinical features was developed and visualized using nomograms.ResultsIn the test cohort, the LightGBM-based radiomics model achieved optimal performance with the Area Under the Curve (AUC) of 0.867, sensitivity of 0.952, and specificity of 0.625. The combined model demonstrated enhanced diagnostic capability with AUC of 0.899, sensitivity of 0.762, and specificity of 0.917. Manual diagnosis of SLAP injury using MRI achieved an accuracy of 50.3%, with a sensitivity of 27.7%, specificity of 78.8%, and AUC of 0.619.ConclusionMachine learning models based on MRI radiomics features demonstrated superior diagnostic accuracy compared to traditional radiologist assessment for SLAP lesions. The combined model incorporating both radiomics and clinical features provides effective risk prediction for SLAP lesions.

背景:上唇前后(SLAP)病变是引起肩部疼痛和不稳定的常见原因。在临床实践中,准确诊断仍然具有挑战性。本研究旨在建立和评估用于SLAP病变检测的放射组学模型和结合放射组学与临床特征的联合模型。方法回顾性研究纳入2019年至2024年间接受肩关节镜手术并术前进行肩关节磁共振成像(MRI)的149例患者。在MRI斜冠状位质子密度加权脂肪抑制(PD FS)图像上手动划定感兴趣区域(roi),随后从这些定义区域提取放射组学特征。特征选择采用独立t检验、Mann-Whitney U检验、Pearson相关分析和最小绝对收缩和选择算子(LASSO)回归。采用支持向量机(SVM)、随机森林(RF)、光梯度增强机(LightGBM)等常用机器学习模型构建基于放射组学特征的诊断模型。结合放射组学和临床特征开发了一个组合模型,并使用图显示。结果在测试队列中,基于lightgbm的放射组学模型的曲线下面积(Area Under the Curve, AUC)为0.867,灵敏度为0.952,特异性为0.625。联合模型的诊断能力增强,AUC为0.899,灵敏度为0.762,特异性为0.917。MRI手工诊断SLAP损伤的准确率为50.3%,敏感性27.7%,特异性78.8%,AUC为0.619。结论基于MRI放射组学特征的机器学习模型与传统放射科医师评估相比,对SLAP病变的诊断准确性更高。结合放射组学和临床特征的联合模型为SLAP病变提供了有效的风险预测。
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引用次数: 0
Modified combined Woodward and Green procedure for adult congenital Sprengel deformity. 改良的Woodward和Green联合手术治疗成人先天性Sprengel畸形。
IF 1.6 4区 医学 Pub Date : 2026-01-01 Epub Date: 2026-01-22 DOI: 10.1177/10225536261418722
Feng Zhu, Wei Mei, Xiangjian Song

ObjectiveTo investigate the clinical efficacy and incidence of complications in the treatment of adult congenital high scapula (Sprengel deformity) using the modified combined Woodward and Green surgical approach.MethodsFrom January 2020 to January 2024, 9 adult patients with congenital Sprengel deformity were treated with the modified Woodward and Green combined procedure. There were two males and seven females, aged 18-35 years (mean: 23.5 ± 4.2 years), with 6 cases on the left and 3 on the right. The surgical procedure involved the modified combined Woodward and Green technique. Postoperatively, routine infection prevention, 4-weeks brace fixation, and rehabilitation guidance were performed. Shoulder appearance was evaluated using the Cavendish grading system; bilateral scapular height difference was measured; and shoulder function was assessed using the UCLA Shoulder Function Rating System, including pain, daily activity ability, range of motion, and muscle strength. Paired t-tests were used to analyze pre- and postoperative data with SPSS 22.0 software.ResultsAll 9 patients were followed up for 12-36 months (mean: 24.11 ± 6.63 months). Postoperatively, shoulder appearance significantly improved, with marked reduction in scapular position, good correction of elevation and shrugging deformities, and near-normal shoulder contour. Cavendish grading improved significantly (p < 0.05). The scapular height difference decreased from 4.50 ± 0.67 cm preoperatively to 0.89 ± 0.77 cm at the last follow-up, and the UCLA shoulder function score increased from 23.44 ± 1.57 to 30.33 ± 0.67, with statistically significant differences (p < 0.001 for both).ConclusionThe modified combined Woodward and Green procedure is a safe and effective treatment for adult congenital Sprengel deformity, significantly improving shoulder appearance and joint function. However, due to the small sample size and short follow-up period, future studies with larger samples and longer follow-ups are needed to accurately evaluate the long-term efficacy.

目的探讨改良Woodward - Green联合入路治疗成人先天性高肩胛骨(Sprengel畸形)的临床疗效及并发症发生率。方法自2020年1月至2024年1月,对9例成人先天性Sprengel畸形采用改良Woodward - Green联合手术治疗。男性2例,女性7例,年龄18 ~ 35岁(平均23.5±4.2岁),左侧6例,右侧3例。手术过程涉及改良的Woodward和Green联合技术。术后常规预防感染,4周支架固定及康复指导。采用卡文迪什评分系统对肩部外观进行评价;测量双侧肩胛骨高度差;使用UCLA肩功能评分系统评估肩部功能,包括疼痛、日常活动能力、活动范围和肌肉力量。采用SPSS 22.0软件对术前和术后数据进行配对t检验。结果9例患者均获得12 ~ 36个月的随访,平均24.11±6.63个月。术后肩部外观明显改善,肩胛骨位置明显降低,抬高和耸肩畸形矫正良好,肩部轮廓接近正常。卡文迪什评分显著提高(p < 0.05)。肩胛骨高度差由术前的4.50±0.67 cm降至末次随访时的0.89±0.77 cm, UCLA肩关节功能评分由23.44±1.57上升至30.33±0.67,差异均有统计学意义(p < 0.001)。结论改良的Woodward和Green联合手术治疗成人先天性Sprengel畸形安全有效,可显著改善肩部外观和关节功能。然而,由于样本量小,随访时间短,未来需要更大样本量和更长随访时间的研究来准确评估长期疗效。
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引用次数: 0
Denosumab treatment after percutaneous vertebroplasty for osteoporotic vertebral compression fractures: Long-term follow-up of pain relief, bone mineral density changes, and risk of refracture. 经皮椎体成形术后Denosumab治疗骨质疏松性椎体压缩性骨折:疼痛缓解、骨密度变化和再骨折风险的长期随访
IF 1.6 4区 医学 Pub Date : 2026-01-01 Epub Date: 2026-01-13 DOI: 10.1177/10225536261417407
Qinglong Li, Huagang Shi, Xing Chen, Simao Song

ObjectiveTo investigate the effects of denosumab on pain relief, bone mineral density (BMD), and refracture risk during long-term follow-up in patients with osteoporotic vertebral compression fractures (OVCF) after percutaneous vertebroplasty, and to identify factors associated with refracture.MethodsThis retrospective study included 396 OVCF patients who underwent percutaneous vertebroplasty and received denosumab between January 2021 and June 2023. Patients were classified into a completed-treatment group (n = 184) and a discontinued-treatment group (n = 212). After 1:1 propensity score matching, 101 patients were included in each group. Changes in visual analog scale (VAS) scores and lumbar spine and femoral neck T-score were compared over 24 months. Refracture risk was assessed using Kaplan-Meier analysis and multivariable Cox regression in the matched cohort.ResultsAfter matching, baseline characteristics were well balanced between groups. Over 24 months of follow-up, the completed-treatment group showed significantly lower VAS scores and greater improvements in lumbar spine and femoral neck T-score compared with the discontinued-treatment group. The incidence of refracture was significantly lower in the completed-treatment group. In the PSM cohort, multivariable Cox regression analysis demonstrated that completed denosumab treatment was independently associated with a lower risk of refracture (HR = 0.314, 95% CI 0.125-0.792, P = 0.014).ConclusionIn patients with OVCF treated with percutaneous vertebroplasty, persistent denosumab therapy for at least 24 months is associated with sustained pain relief, improved BMD, and a lower risk of refracture, underscoring the importance of long-term treatment adherence.

目的探讨denosumab对骨质疏松性椎体压缩性骨折(OVCF)患者经皮椎体成形术后长期随访期间疼痛缓解、骨密度(BMD)和再骨折风险的影响,并探讨再骨折的相关因素。方法本回顾性研究纳入了396例OVCF患者,这些患者在2021年1月至2023年6月期间接受了经皮椎体成形术并接受了denosumab。将患者分为完成治疗组(184例)和停止治疗组(212例)。经1:1倾向评分匹配,每组101例。比较两组24个月内视觉模拟评分(VAS)、腰椎及股骨颈t评分的变化。在匹配队列中使用Kaplan-Meier分析和多变量Cox回归评估再骨折风险。结果组间基线特征匹配良好。在24个月的随访中,与停止治疗组相比,完成治疗组的VAS评分明显降低,腰椎和股骨颈t评分的改善更大。完全治疗组的再骨折发生率明显降低。在PSM队列中,多变量Cox回归分析显示,完成denosumab治疗与再骨折风险降低独立相关(HR = 0.314, 95% CI 0.125-0.792, P = 0.014)。结论在经皮椎体成形术治疗的OVCF患者中,持续地诺单抗治疗至少24个月与持续疼痛缓解、改善骨密度和降低再骨折风险相关,强调了长期治疗依从性的重要性。
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引用次数: 0
Correlation between visceral adiposity index, body roundness index, lipid accumulation product and the risk and severity of knee osteoarthritis. 内脏脂肪指数、体圆度指数、脂质堆积积与膝骨关节炎风险及严重程度的相关性研究。
IF 1.6 4区 医学 Pub Date : 2026-01-01 Epub Date: 2026-02-05 DOI: 10.1177/10225536261422525
Lilan Peng, Jing Yan, Yuquan Zhou, Qing He, Yunshan He, Niuxiu Li, Jianjun Zhou

ObjectiveThis study examined the associations of visceral adiposity index (VAI), body roundness index (BRI), and lipid accumulation product (LAP) with the risk, severity, and prognosis of knee osteoarthritis (KOA). The aim was to evaluate the clinical utility of these novel adiposity indices for early screening and prognostic assessment of KOA.MethodsA total of 124 patients with clinically and radiographically confirmed KOA and 120 healthy individuals who underwent routine physical examinations during the same period were enrolled as the KOA and control groups, respectively. Baseline data were collected retrospectively from electronic medical records. KOA patients were further classified into mild, moderate, and severe subgroups based on K-L grading and were followed for 12 months.ResultsCompared with controls, the KOA group had significantly higher BMI, TG, TC, LDL-C, VAI, BRI, and LAP, and lower HDL-C (p < 0.05). VAI, BRI, and LAP increased progressively with KOA severity (p < 0.05), showing positive correlations (r = 0.608, 0.489, 0.551, p < 0.001), and were confirmed as independent risk factors (p < 0.05). ROC analysis yielded AUCs of 0.775 (95% CI: 0.718-0.833; cutoff: 2.91) for VAI, 0.752 (95% CI: 0.692-0.813; cutoff: 5.21) for BRI, and 0.779 (95% CI: 0.722-0.836; cutoff: 48.58) for LAP, with a combined AUC of 0.880 (95% CI: 0.839-0.922). Survival time differed significantly across groups stratified by these cutoffs (VAI: χ2 = 4.238; BRI: χ2 = 3.956; LAP: χ2 = 6.043; all p < 0.05).ConclusionThis study concludes that VAI, BRI, and LAP are closely linked to KOA. Firstly, their levels are significantly raised in patients and show a positive correlation with disease severity, marking them as useful clinical indicators. Secondly, the combined detection of these indices provides superior predictive value for KOA and is associated with an unfavorable prognosis, suggesting their utility in comprehensive risk assessment.

目的探讨内脏脂肪指数(VAI)、体圆度指数(BRI)和脂质积累产物(LAP)与膝骨关节炎(KOA)的风险、严重程度和预后的关系。目的是评估这些新型肥胖指数在KOA早期筛查和预后评估中的临床应用。方法选取124例经临床及影像学证实的KOA患者和120例同期进行常规体检的健康人,分别作为KOA组和对照组。从电子病历中回顾性收集基线数据。根据K-L分级将KOA患者进一步分为轻度、中度和重度亚组,随访12个月。结果与对照组比较,KOA组患者BMI、TG、TC、LDL-C、VAI、BRI、LAP显著升高,HDL-C显著降低(p < 0.05)。VAI、BRI、LAP随KOA严重程度逐渐升高(p < 0.05),呈正相关(r = 0.608、0.489、0.551,p < 0.001),为独立危险因素(p < 0.05)。ROC分析得出,VAI的AUC为0.775 (95% CI: 0.718-0.833;截止日期:2.91),BRI的AUC为0.752 (95% CI: 0.692-0.813;截止日期:5.21),LAP的AUC为0.779 (95% CI: 0.722-0.836;截止日期:48.58),合并AUC为0.880 (95% CI: 0.839-0.922)。按这些截断点分层的各组生存时间差异显著(VAI: χ2 = 4.238; BRI: χ2 = 3.956; LAP: χ2 = 6.043;均p < 0.05)。结论VAI、BRI和LAP与KOA密切相关。首先,它们的水平在患者体内显著升高,并与疾病严重程度呈正相关,是有用的临床指标。其次,这些指标的联合检测对KOA的预测价值较高,但与不良预后相关,可用于综合风险评估。
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引用次数: 0
Predictive value of monocyte-to-albumin ratio, red cell distribution with-to-albumin ratio, hemoglobin-to-albumin ratio, leukocyte-to-albumin ratio, and platelet-to-albumin ratio for 14-day readmission following primary total knee arthroplasty. 单核细胞-白蛋白比、红细胞分布与白蛋白比、血红蛋白-白蛋白比、白细胞-白蛋白比和血小板-白蛋白比对初次全膝关节置换术后14天再入院的预测价值。
IF 1.6 4区 医学 Pub Date : 2026-01-01 Epub Date: 2026-01-22 DOI: 10.1177/10225536261417467
Ngi-Chiong Lau, Ching-Wei Hu, Chih-Chien Hu, Yu-Yi Huang, Pin-Ren Huang, Dave W Chen

Total knee arthroplasty (TKA) is a frequently performed surgery for restoring function in patients with severe knee osteoarthritis. TKA is associated with significant healthcare costs, partly due to complications leading to readmissions. This study aimed to identify biomarkers predictive of readmission after TKA. Data of adult patients who underwent primary TKA between 2014 and 2022 extracted from the Chang Gung Medical Research Database were retrospectively reviewed. Associations between the monocyte-to-albumin ratio (MAR), red cell distribution with (RDW)-to-albumin ratio (RAR), hemoglobin-to-albumin ratio (HAR), leukocyte-to-albumin ratio (LAR), and platelet-to-albumin ratio (PAR) with 14-day readmission were determined using univariate and multivariable regression analyses. A score termed the 'MAR-LAR-PAR' score was developed using the combination of these 3 markers, and its prognostic value was assessed. Data from 1,137 patients were included. Elevated MAR (adjusted odds ratio [aOR] = 1.77, 95% confidence interval [CI]: 1.08-2.89, p = 0.022), LAR (aOR = 1.59, 95% CI: 1.02-2.45, p = 0.039), and PAR (aOR = 1.88, 95% CI: 1.12-3.15, p = 0.016) were significantly associated with increased risk of 14-day readmission. The highest MAR-LAR-PAR score (score = 3) was significantly associated with 14-day readmission compared to score = 0 (aOR = 4.24, 95% CI: 1.91-9.44, p < 0.001). This study highlights the potential of MAR, LAR, PAR, and the score based on their combination, as significant predictors of short-term readmission following TKA. Incorporating these biomarkers into preoperative assessment may help determine the risk of readmission, and provide additional care for these patients.

全膝关节置换术(TKA)是严重膝骨关节炎患者常用的恢复功能的手术。TKA与大量医疗费用相关,部分原因是并发症导致再入院。本研究旨在确定预测TKA后再入院的生物标志物。从长庚医学研究数据库中提取的2014年至2022年间接受原发性TKA的成年患者的数据进行回顾性分析。使用单变量和多变量回归分析确定14天再入院时单核细胞-白蛋白比(MAR)、红细胞分布(RDW)-白蛋白比(RAR)、血红蛋白-白蛋白比(HAR)、白细胞-白蛋白比(LAR)和血小板-白蛋白比(PAR)之间的关系。将这3种指标联合使用,形成“MAR-LAR-PAR”评分,并评估其预后价值。数据来自1137名患者。MAR(调整优势比[aOR] = 1.77, 95%可信区间[CI]: 1.08-2.89, p = 0.022)、LAR (aOR = 1.59, 95% CI: 1.02-2.45, p = 0.039)和PAR (aOR = 1.88, 95% CI: 1.12-3.15, p = 0.016)升高与14天再入院风险增加显著相关。与评分为0的患者相比,最高MAR-LAR-PAR评分(评分为3)与14天再入院显著相关(aOR = 4.24, 95% CI: 1.91-9.44, p < 0.001)。本研究强调了MAR、LAR、PAR和基于它们组合的评分作为TKA后短期再入院的重要预测指标的潜力。将这些生物标志物纳入术前评估可能有助于确定再入院的风险,并为这些患者提供额外的护理。
{"title":"Predictive value of monocyte-to-albumin ratio, red cell distribution with-to-albumin ratio, hemoglobin-to-albumin ratio, leukocyte-to-albumin ratio, and platelet-to-albumin ratio for 14-day readmission following primary total knee arthroplasty.","authors":"Ngi-Chiong Lau, Ching-Wei Hu, Chih-Chien Hu, Yu-Yi Huang, Pin-Ren Huang, Dave W Chen","doi":"10.1177/10225536261417467","DOIUrl":"https://doi.org/10.1177/10225536261417467","url":null,"abstract":"<p><p>Total knee arthroplasty (TKA) is a frequently performed surgery for restoring function in patients with severe knee osteoarthritis. TKA is associated with significant healthcare costs, partly due to complications leading to readmissions. This study aimed to identify biomarkers predictive of readmission after TKA. Data of adult patients who underwent primary TKA between 2014 and 2022 extracted from the Chang Gung Medical Research Database were retrospectively reviewed. Associations between the monocyte-to-albumin ratio (MAR), red cell distribution with (RDW)-to-albumin ratio (RAR), hemoglobin-to-albumin ratio (HAR), leukocyte-to-albumin ratio (LAR), and platelet-to-albumin ratio (PAR) with 14-day readmission were determined using univariate and multivariable regression analyses. A score termed the 'MAR-LAR-PAR' score was developed using the combination of these 3 markers, and its prognostic value was assessed. Data from 1,137 patients were included. Elevated MAR (adjusted odds ratio [aOR] = 1.77, 95% confidence interval [CI]: 1.08-2.89, <i>p</i> = 0.022), LAR (aOR = 1.59, 95% CI: 1.02-2.45, <i>p</i> = 0.039), and PAR (aOR = 1.88, 95% CI: 1.12-3.15, <i>p</i> = 0.016) were significantly associated with increased risk of 14-day readmission. The highest MAR-LAR-PAR score (score = 3) was significantly associated with 14-day readmission compared to score = 0 (aOR = 4.24, 95% CI: 1.91-9.44, <i>p</i> < 0.001). This study highlights the potential of MAR, LAR, PAR, and the score based on their combination, as significant predictors of short-term readmission following TKA. Incorporating these biomarkers into preoperative assessment may help determine the risk of readmission, and provide additional care for these patients.</p>","PeriodicalId":16608,"journal":{"name":"Journal of Orthopaedic Surgery","volume":"34 1","pages":"10225536261417467"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146018607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of epidural patient-controlled analgesia on pain relief after lumbar spinal surgeries-a case-control study. 患者自控硬膜外镇痛对腰椎手术后疼痛缓解的影响——病例对照研究。
IF 1.6 4区 医学 Pub Date : 2026-01-01 Epub Date: 2026-01-07 DOI: 10.1177/10225536261415693
Hsin-Chang Chen, Jin-Huei Yu, Ming-Han Hsieh, Shih-Liang Shih

PurposePatients withspinal degenerative diseases are often older and have multiple comorbidities. This study aims to evaluate the impact of epidural patient-controlled analgesia (PCA) on postoperative pain relief in patients undergoing lumbar spine surgeries for spinal degenerative diseases.MethodsThis retrospective case-control study included patients who underwent lumbar spine surgeries for degenerative spinal stenosis, spondylolisthesis, herniated intervertebral discs, or osteoporotic spinal fractures with spinal stenosis. The PCA group consisted of patients who received 72-h epidural PCA for postoperative pain control, while the control group received standard postoperative pain management. All patients were allowed to request intramuscular rescue analgesics for additional pain control. The primary endpoint was defined as the mean visual analogue scale (VAS) score during the effective PCA period (postoperative day [POD] 1-3). Secondary endpoints included individual daily VAS scores, rebound pain, rescue analgesic injections, morphine consumption, drainage duration, drainage volume, length of hospital stay, and complications.ResultsA total of 209 patients (mean age 73.8 years) were included, with 88 patients in the PCA group and 121 in the control group. Mean VAS score across POD 1-3 was significantly lower in the PCA group (Cohen's d = -1.89, 95% CI = -2.22 to -1.56, p < 0.001). During hospitalization, the PCA group required significantly fewer rescue analgesic injections (Cohen's d = -2.47, 95% CI = -2.84 to -2.11) and less total morphine consumption (Cohen's d = -0.39, 95% CI = -0.67 to -0.11) compared to the control group. Although the PCA group experienced greater drainage volume and longer duration of drainage placement, the incidence of infection and the length of hospital stay were comparable between the two groups.ConclusionIn this real-world cohort of elderly patients with multiple comorbidities undergoing lumbar spinal surgery, epidural PCA provided effective pain relief without an observed increase in infection rates in this study population.

目的脊柱退行性疾病患者通常年龄较大,并伴有多种合并症。本研究旨在评估硬膜外患者自控镇痛(PCA)对腰椎退行性疾病手术患者术后疼痛缓解的影响。方法本回顾性病例对照研究纳入因退行性椎管狭窄、椎体滑脱、椎间盘突出或骨质疏松性椎管狭窄而行腰椎手术的患者。PCA组患者接受72小时硬膜外PCA进行术后疼痛控制,对照组患者接受标准的术后疼痛管理。所有患者均可要求肌内急救镇痛以进一步控制疼痛。主要终点定义为有效PCA期间(术后1-3天[POD])的平均视觉模拟评分(VAS)评分。次要终点包括个人每日VAS评分、反弹疼痛、抢救性镇痛注射、吗啡用量、引流时间、引流量、住院时间和并发症。结果共纳入209例患者,平均年龄73.8岁,其中PCA组88例,对照组121例。PCA组POD 1-3的VAS平均评分显著降低(Cohen’s d = -1.89, 95% CI = -2.22 ~ -1.56, p < 0.001)。在住院期间,与对照组相比,PCA组需要更少的抢救性镇痛注射(Cohen’s d = -2.47, 95% CI = -2.84 ~ -2.11)和更少的吗啡总用量(Cohen’s d = -0.39, 95% CI = -0.67 ~ -0.11)。虽然PCA组引流量更大,引流时间更长,但两组的感染发生率和住院时间相当。结论:在这个现实世界的队列中,有多种合并症的老年患者接受腰椎手术,硬膜外PCA提供了有效的疼痛缓解,而没有观察到感染率的增加。
{"title":"Effect of epidural patient-controlled analgesia on pain relief after lumbar spinal surgeries-a case-control study.","authors":"Hsin-Chang Chen, Jin-Huei Yu, Ming-Han Hsieh, Shih-Liang Shih","doi":"10.1177/10225536261415693","DOIUrl":"https://doi.org/10.1177/10225536261415693","url":null,"abstract":"<p><p>PurposePatients withspinal degenerative diseases are often older and have multiple comorbidities. This study aims to evaluate the impact of epidural patient-controlled analgesia (PCA) on postoperative pain relief in patients undergoing lumbar spine surgeries for spinal degenerative diseases.MethodsThis retrospective case-control study included patients who underwent lumbar spine surgeries for degenerative spinal stenosis, spondylolisthesis, herniated intervertebral discs, or osteoporotic spinal fractures with spinal stenosis. The PCA group consisted of patients who received 72-h epidural PCA for postoperative pain control, while the control group received standard postoperative pain management. All patients were allowed to request intramuscular rescue analgesics for additional pain control. The primary endpoint was defined as the mean visual analogue scale (VAS) score during the effective PCA period (postoperative day [POD] 1-3). Secondary endpoints included individual daily VAS scores, rebound pain, rescue analgesic injections, morphine consumption, drainage duration, drainage volume, length of hospital stay, and complications.ResultsA total of 209 patients (mean age 73.8 years) were included, with 88 patients in the PCA group and 121 in the control group. Mean VAS score across POD 1-3 was significantly lower in the PCA group (Cohen's <i>d</i> = -1.89, 95% CI = -2.22 to -1.56, <i>p</i> < 0.001). During hospitalization, the PCA group required significantly fewer rescue analgesic injections (Cohen's d = -2.47, 95% CI = -2.84 to -2.11) and less total morphine consumption (Cohen's <i>d</i> = -0.39, 95% CI = -0.67 to -0.11) compared to the control group. Although the PCA group experienced greater drainage volume and longer duration of drainage placement, the incidence of infection and the length of hospital stay were comparable between the two groups.ConclusionIn this real-world cohort of elderly patients with multiple comorbidities undergoing lumbar spinal surgery, epidural PCA provided effective pain relief without an observed increase in infection rates in this study population.</p>","PeriodicalId":16608,"journal":{"name":"Journal of Orthopaedic Surgery","volume":"34 1","pages":"10225536261415693"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145917825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A prospective randomized controlled study on the effect of a novel exsanguination tourniquet in fresh closed distal radius fracture surgery. 一项关于新型止血止血带在桡骨远端骨折手术中的应用效果的前瞻性随机对照研究。
IF 1.6 4区 医学 Pub Date : 2025-09-01 Epub Date: 2025-12-21 DOI: 10.1177/10225536251411001
Binbin Sun, Jianjie Xu, Jianhao Yu, Songlin Tong, Yi Zhang, Weifeng Zhou

PurposeThis study aimed to evaluate the efficacy and safety of an elastic constriction ring compared to traditional pneumatic tourniquets in patients undergoing surgery for closed distal radius fractures.MethodsA total of 60 participants were enrolled, with 30 in the experimental group (elastic constriction ring) and 30 in the control group (traditional tourniquet). Key indicators assessed included preoperative exsanguination time, intraoperative blood loss, tourniquet-related complications, and so on.ResultsThe experimental group demonstrated a significantly shorter average exsanguination time (8.36 ± 2.72 s vs 55.98 ± 3.61 s) and lower intraoperative blood loss (12.07 ± 6.54 mL vs 17.07 ± 8.29 mL). No significant differences were observed in tourniquet time or operation time between the groups. Besides, adverse events related to the device are minimal in two groups.ConclusionsThe elastic constriction ring is an effective alternative to traditional pneumatic tourniquets, offering significant advantages in reducing exsanguination time and intraoperative blood loss without increasing complication rates.

目的本研究旨在评价弹性收缩环与传统气动止血带在桡骨远端闭合性骨折手术患者中的疗效和安全性。方法共60例受试者,实验组(弹性缩窄环)30例,对照组(传统止血带)30例。评估的关键指标包括术前放血时间、术中出血量、止血带相关并发症等。结果实验组平均放血时间明显缩短(8.36±2.72 s vs 55.98±3.61 s),术中出血量明显减少(12.07±6.54 mL vs 17.07±8.29 mL)。两组间止血带时间和手术时间均无显著差异。此外,两组患者与器械相关的不良事件最少。结论弹性收缩环是传统气动止血带的有效替代方案,在减少放血时间和术中出血量方面具有显著优势,且不增加并发症发生率。
{"title":"A prospective randomized controlled study on the effect of a novel exsanguination tourniquet in fresh closed distal radius fracture surgery.","authors":"Binbin Sun, Jianjie Xu, Jianhao Yu, Songlin Tong, Yi Zhang, Weifeng Zhou","doi":"10.1177/10225536251411001","DOIUrl":"10.1177/10225536251411001","url":null,"abstract":"<p><p>PurposeThis study aimed to evaluate the efficacy and safety of an elastic constriction ring compared to traditional pneumatic tourniquets in patients undergoing surgery for closed distal radius fractures.MethodsA total of 60 participants were enrolled, with 30 in the experimental group (elastic constriction ring) and 30 in the control group (traditional tourniquet). Key indicators assessed included preoperative exsanguination time, intraoperative blood loss, tourniquet-related complications, and so on.ResultsThe experimental group demonstrated a significantly shorter average exsanguination time (8.36 ± 2.72 s vs 55.98 ± 3.61 s) and lower intraoperative blood loss (12.07 ± 6.54 mL vs 17.07 ± 8.29 mL). No significant differences were observed in tourniquet time or operation time between the groups. Besides, adverse events related to the device are minimal in two groups.ConclusionsThe elastic constriction ring is an effective alternative to traditional pneumatic tourniquets, offering significant advantages in reducing exsanguination time and intraoperative blood loss without increasing complication rates.</p>","PeriodicalId":16608,"journal":{"name":"Journal of Orthopaedic Surgery","volume":"33 3","pages":"10225536251411001"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145805022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical management of lateral ulnar collateral ligament injuries in elbow dislocations and fracture-dislocations: Comparative outcomes of primary repair and palmaris longus tendon reconstruction. 肘关节脱位和骨折脱位后外侧尺侧副韧带损伤的手术治疗:初级修复和掌长肌腱重建的比较结果。
IF 1.6 4区 医学 Pub Date : 2025-09-01 Epub Date: 2025-10-08 DOI: 10.1177/10225536251387310
Eralp Erdogan, Zafer Gunes

ObjectivesThis study compared outcomes of primary repair and palmaris longus tendon reconstruction in patients with lateral ulnar collateral ligament (LUCL) injuries.Material and MethodA retrospective comparative cohort study was conducted between 2017 and 2023, including 40 patients who underwent surgery for elbow dislocation or fracture-dislocation with intraoperatively confirmed LUCL injury. Surgical choice was made intraoperatively: repair was performed if the ligament could be reattached without tension, while reconstruction was selected if the tissue was shortened, retracted, or degenerative. Patients were divided into a repair group (n = 17) and a reconstruction group (n = 23). Clinical outcomes included Visual Analog Scale (VAS), Quick Disabilities of the Arm, Shoulder and Hand (QuickDASH), Mayo Elbow Performance Score (MEPS), range of motion (ROM), fracture healing, and complications, with a mean follow-up of 26.4 months.ResultsThe repair group showed mean VAS 16.2, QuickDASH 9.7, MEPS 89.9, and ROM 137.2°, while the reconstruction group had VAS 17.2, QuickDASH 8.4, MEPS 89.0, and ROM 133.6°. There were no significant differences in VAS, QuickDASH, or MEPS, though the repair group demonstrated superior ROM (p = 0.029). The absolute ROM difference (∼3-4°) was not considered clinically meaningful. In isolated LUCL cases (n = 15), no significant differences were observed between groups. All associated fractures achieved union without non-union or malunion. Complications included heterotopic ossification in seven patients (three repairs, four reconstructions) and two superficial infections, all successfully managed without reoperation. No patient developed recurrent instability, nerve deficits, or clinically significant stiffness.ConclusionBoth primary repair and palmaris longus tendon reconstruction provided satisfactory outcomes and durable stability. Although the repair group showed slightly greater ROM, this difference was not clinically relevant and disappeared when patients with concomitant fractures were excluded. Injury complexity, rather than surgical technique, appears to be the main determinant of long-term function.

目的比较尺侧副韧带(LUCL)损伤患者的初级修复和掌长肌腱重建的效果。材料与方法2017 - 2023年进行回顾性比较队列研究,纳入40例手术治疗肘关节脱位或骨折脱位并术中确认LUCL损伤的患者。术中进行手术选择:如果韧带可以无张力地重新连接,则进行修复,如果组织缩短、收缩或退行性变,则选择重建。患者分为修复组(17例)和重建组(23例)。临床结果包括视觉模拟量表(VAS)、手臂、肩膀和手的快速残疾(QuickDASH)、梅奥肘部功能评分(MEPS)、活动范围(ROM)、骨折愈合和并发症,平均随访26.4个月。结果修复组平均VAS 16.2, QuickDASH 9.7, MEPS 89.9, ROM 137.2°;重建组平均VAS 17.2, QuickDASH 8.4, MEPS 89.0, ROM 133.6°。VAS、QuickDASH、MEPS均无显著差异,修复组ROM优于对照组(p = 0.029)。绝对ROM差异(~ 3-4°)被认为没有临床意义。在孤立的LUCL病例中(n = 15),两组间无显著差异。所有相关骨折均愈合,无骨不连或畸形愈合。并发症包括7例患者异位骨化(3例修复,4例重建)和2例浅表感染,均成功处理,无需再次手术。没有患者出现复发性不稳定、神经缺损或临床上明显的僵硬。结论初级修复和掌长肌腱重建均能获得满意的结果和持久的稳定性。虽然修复组的ROM稍大,但这种差异没有临床意义,当排除合并骨折的患者时,这种差异就消失了。损伤的复杂性,而不是手术技术,似乎是长期功能的主要决定因素。
{"title":"Surgical management of lateral ulnar collateral ligament injuries in elbow dislocations and fracture-dislocations: Comparative outcomes of primary repair and palmaris longus tendon reconstruction.","authors":"Eralp Erdogan, Zafer Gunes","doi":"10.1177/10225536251387310","DOIUrl":"https://doi.org/10.1177/10225536251387310","url":null,"abstract":"<p><p>ObjectivesThis study compared outcomes of primary repair and palmaris longus tendon reconstruction in patients with lateral ulnar collateral ligament (LUCL) injuries.Material and MethodA retrospective comparative cohort study was conducted between 2017 and 2023, including 40 patients who underwent surgery for elbow dislocation or fracture-dislocation with intraoperatively confirmed LUCL injury. Surgical choice was made intraoperatively: repair was performed if the ligament could be reattached without tension, while reconstruction was selected if the tissue was shortened, retracted, or degenerative. Patients were divided into a repair group (n = 17) and a reconstruction group (n = 23). Clinical outcomes included Visual Analog Scale (VAS), Quick Disabilities of the Arm, Shoulder and Hand (QuickDASH), Mayo Elbow Performance Score (MEPS), range of motion (ROM), fracture healing, and complications, with a mean follow-up of 26.4 months.ResultsThe repair group showed mean VAS 16.2, QuickDASH 9.7, MEPS 89.9, and ROM 137.2°, while the reconstruction group had VAS 17.2, QuickDASH 8.4, MEPS 89.0, and ROM 133.6°. There were no significant differences in VAS, QuickDASH, or MEPS, though the repair group demonstrated superior ROM (p = 0.029). The absolute ROM difference (∼3-4°) was not considered clinically meaningful. In isolated LUCL cases (n = 15), no significant differences were observed between groups. All associated fractures achieved union without non-union or malunion. Complications included heterotopic ossification in seven patients (three repairs, four reconstructions) and two superficial infections, all successfully managed without reoperation. No patient developed recurrent instability, nerve deficits, or clinically significant stiffness.ConclusionBoth primary repair and palmaris longus tendon reconstruction provided satisfactory outcomes and durable stability. Although the repair group showed slightly greater ROM, this difference was not clinically relevant and disappeared when patients with concomitant fractures were excluded. Injury complexity, rather than surgical technique, appears to be the main determinant of long-term function.</p>","PeriodicalId":16608,"journal":{"name":"Journal of Orthopaedic Surgery","volume":"33 3","pages":"10225536251387310"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145251628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cannulated screw versus kirschner wire fixation for pediatric medial epicondylar fractures: Focusing on pain management and complication patterns. 空心螺钉与克氏针固定治疗小儿内上髁骨折:关注疼痛管理和并发症模式。
IF 1.6 4区 医学 Pub Date : 2025-09-01 Epub Date: 2025-10-18 DOI: 10.1177/10225536251391386
Fengkun Ji, Zhendong Wang, Hui Chen, Xiangling Deng, Huixia Zhou, Wenchao Li

ObjectiveTo evaluate and compare pain management, complication patterns, and functional outcomes between cannulated screw and Kirschner wire fixation for treating pediatric medial epicondylar fractures.MethodA retrospective cohort study was conducted at a tertiary hospital from 2013 to 2023, involving 31 pediatric patients with displaced medial epicondylar fractures (Watson-Jones Types III and IV). Patients were divided into two groups: 16 received cannulated screw fixation, while 15 underwent Kirschner wire fixation. Clinical outcomes, including operation time, fracture healing, pain levels, and complications, were assessed.ResultsBoth groups demonstrated similar long-term functional outcomes, with no significant difference in Mayo Elbow Performance Scores (p > 0.05). The cannulated screw group experienced significantly lower pain on the third postoperative day compared to the Kirschner wire group (p < 0.001). The Kirschner wire group had a higher rate of pin-track infections (13.3%) and delayed union (6.7%), whereas the cannulated screw group had fewer complications, with one case of superficial wound infection. Hardware removal occurred significantly earlier in the Kirschner wire group (p < 0.001).ConclusionBoth fixation methods offer effective treatment for pediatric medial epicondylar fractures, with cannulated screws providing better pain control and fewer complications but requiring longer retention. Kirschner wires allow for earlier removal but carry a higher risk of infection and delayed healing. Treatment decisions should be individualized, considering factors such as pain sensitivity, family preferences, and medical resources.

目的评价和比较空心螺钉和克氏针内固定治疗小儿内上髁骨折的疼痛处理、并发症模式和功能结局。方法回顾性队列研究于2013年至2023年在某三级医院进行,纳入31例患儿移位性内上髁骨折(Watson-Jones III型和IV型)。患者分为两组:16例采用空心螺钉固定,15例采用克氏针固定。评估临床结果,包括手术时间、骨折愈合、疼痛程度和并发症。结果两组患者的长期功能预后相似,Mayo肘关节功能评分无显著差异(p < 0.05)。与克氏针组相比,空心螺钉组术后第3天疼痛明显减轻(p < 0.001)。克氏针组有较高的针道感染率(13.3%)和延迟愈合率(6.7%),而空心螺钉组并发症较少,仅有1例浅表伤口感染。克氏针组的硬体取出明显早于对照组(p < 0.001)。结论两种固定方法均能有效治疗小儿内上髁骨折,空心螺钉能更好地控制疼痛,并发症少,但需要更长的固定时间。克氏针可以尽早取出,但有较高的感染和延迟愈合的风险。治疗决定应个体化,考虑诸如疼痛敏感性、家庭偏好和医疗资源等因素。
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引用次数: 0
The therapeutic effect of robot-assisted double-threaded pedicle screws in the treatment of osteoporotic lumbar spondylolisthesis. 机器人辅助双螺纹椎弓根螺钉治疗骨质疏松性腰椎滑脱的疗效观察。
IF 1.6 4区 医学 Pub Date : 2025-09-01 Epub Date: 2025-10-29 DOI: 10.1177/10225536251392628
Bin Xie, Hongda Xu, Haitao Deng, Mingfan Li, Shengxing Zhao, Yuankun Gou, Lei Zhang, Tieheng Wang, Youpeng Hu, Shiming Xie, Peidong Qing

ObjectiveThe feasibility of placing longer, larger diameter double-threaded screws into the pedicle for good fixation in osteoporotic patients with lumbar spondylolisthesis was investigated via robot-assisted optimal access planning.MethodA total of 80 patients with degenerative lumbar spondylolisthesis needed posterior incision decompression and bone grafting combined with pedicle screw fixation due to spondylolisthesis. The patients were equally and randomly assigned to a robot-assisted group and a bone cement-strengthened group. The operative time, intraoperative blood loss, and intraoperative radiation dose were recorded. X-ray and CT scans were routinely reviewed after the surgery. The ratio of screw diameter to pedicle width (SD/PW) was calculated. The pedicle position was graded. The Bub score assessed proximal facet joint invasion. Visual analogue pain scale (VAS) was recorded before surgery and 3 days after surgery. The Oswestry Disability Index (ODI) and health Survey Summary Form (SF-36 to assess patients' quality of life) were performed before surgery and 6 months after surgery. The rate of screw loosening, removal, complications and revision were evaluated by X-ray and CT 12 months after operation.ResultsVAS score on day 3 after surgery was significantly better in the robot-assisted group than in the bone cement-strengthened group. (p = 0.027). The operative time and intraoperative radiation dose of the robot-assisted group were lower than those of the bone cement-strengthened group (p < 0.001). The ratios of screw length, screw diameter, and SD/PW in both groups were significantly better in the robot-assisted group than in the bone cement-strengthened group (p < 0.001). The incidence of screw small joint invasion was 10.2% in the robot-assisted group and 19.1% in the bone cement-strengthened group, with a statistically significant difference between the two (p = 0.020). The Oswestry Disability Index (ODI) and Health Survey Summary Form (SF-36) at 6 months after surgery were significantly improved in both groups.ConclusionPatients with osteoporotic lumbar spondylolisthesis who use robot assistance to implant longer, thicker-diameter double-threaded screws achieved a similar fixation effect as those of bone cement-reinforced screws. Meanwhile, the operation time was shorter, the radiation damage was less, and the difficulty of later revision surgery was reduced. Thus, the proposed surgical protocol can be applied as a new option for patients with osteoporotic lumbar spondylolisthesis.

目的通过机器人辅助最佳通路规划,探讨骨质疏松伴腰椎滑脱患者椎弓根内置入更长、更大直径双螺纹螺钉的可行性。方法对80例退行性腰椎滑脱患者进行腰椎滑脱后切口减压植骨联合椎弓根螺钉固定。患者被平等地随机分配到机器人辅助组和骨水泥强化组。记录手术时间、术中出血量、术中放射剂量。术后例行复查x光片和CT扫描。计算螺钉直径与椎弓根宽度之比(SD/PW)。对椎弓根位置进行分级。Bub评分评估近端小关节侵犯。术前和术后3 d分别记录视觉模拟疼痛评分(VAS)。术前和术后6个月分别进行Oswestry残疾指数(ODI)和健康调查摘要表(SF-36)评估患者的生活质量。术后12个月通过x线及CT评估螺钉松动、取出、并发症及翻修率。结果机器人辅助组术后第3天vas评分明显优于骨水泥强化组。(p = 0.027)。机器人辅助组的手术时间和术中辐射剂量均低于骨水泥增强组(p < 0.001)。机器人辅助组的螺钉长度、直径、SD/PW比均显著优于骨水泥增强组(p < 0.001)。机器人辅助组螺钉小关节侵犯发生率为10.2%,骨水泥增强组为19.1%,两者差异有统计学意义(p = 0.020)。术后6个月,两组患者的Oswestry残疾指数(ODI)和健康调查摘要表(SF-36)均有显著改善。结论骨质疏松性腰椎滑脱患者使用机器人辅助植入更长、更粗直径的双螺纹螺钉与骨水泥增强螺钉的固定效果相似。同时手术时间短,放射损伤小,降低了后期翻修手术的难度。因此,建议的手术方案可以作为骨质疏松性腰椎滑脱患者的新选择。
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引用次数: 0
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Journal of Orthopaedic Surgery
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