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Working Status of First-Time Postpartum Mothers and Telomere Length-A 1-Year Prospective Study. 产后母亲工作状态与端粒长度的1年前瞻性研究。
IF 3.2 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-12-01 Epub Date: 2023-09-12 DOI: 10.1097/JOM.0000000000002966
Nourit Houminer-Klepar, Shiran Bord, Elissa Epel, Jue Lin, Linoy Sultan, Orna Baron-Epel

Objective: Transitioning to motherhood can create work family conflicts affecting mothers' health. Although employment is generally associated with longer telomeres, this may diminish during the early years of child-rearing. This study aimed to assess the impact of work reentry on telomere length (TL) among first-time mothers.

Methods: In this 1-year prospective study, a total of 103 first-time postpartum mothers participated from two medical institutions in Northern Israel; they completed validated questionnaires, reported their current working status, and provided dried blood spots measuring TL.

Results: We found that working status significantly predicted change in TL and was negatively correlated with change in TL over time (β = -0.245; 95% confidence interval, -0.169, -0.018; P = 0.016).

Conclusions: Identifying ideal timing of work reentry is recommended for first-time postpartum mother's optimal health and TL.

目的:转变为母亲可能造成影响母亲健康的工作与家庭冲突。虽然就业通常与较长的端粒有关,但在养育孩子的早期,这种情况可能会减少。本研究旨在评估职场再就业对初产母亲端粒长度(TL)的影响。方法:在这项为期1年的前瞻性研究中,来自以色列北部两家医疗机构的103名首次产后母亲参与了这项研究;他们完成了有效的问卷,报告了他们目前的工作状态,并提供了测量TL的干血点。结果:我们发现工作状态显著预测TL的变化,并与TL随时间的变化呈负相关(β = -0.245;95%置信区间,-0.169,-0.018;P = 0.016)。结论:确定理想的重返工作时间对初次产后母亲的最佳健康和产后生活是有帮助的。
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引用次数: 0
Comparing Longitudinal Measures of Cholinesterase as Biomarkers for Insecticide Exposure Among Latinx Children in Rural Farmworker and Urban Nonfarmworker Communities in North Carolina. 比较北卡罗来纳州农村农场工人和城市非农场工人社区拉丁裔儿童胆碱酯酶作为杀虫剂暴露生物标志物的纵向测量。
IF 2.3 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-12-01 Epub Date: 2023-09-06 DOI: 10.1097/JOM.0000000000002965
Sara A Quandt, Sydney A Smith, Thomas A Arcury, Haiying Chen, Kirstin Hester, Carey N Pope, Kim A Anderson, Paul J Laurienti

Objective: In a 2-group prospective design, this study compared seasonal cholinesterase levels of Latinx children in rural farmworker families and comparable urban children to assess the impact of environmental exposure to cholinesterase-inhibiting insecticides.

Methods: Quarterly blood samples and passive dosimeter wristbands were collected over 2 years in 8-year-old children (74 rural, 62 urban). Laboratory analysis assessed total cholinesterase, acetylcholinesterase, and butyrylcholinesterase from blood samples, and insecticides from wristbands.

Results: In spring and summer, total cholinesterase and acetylcholinesterase levels were depressed in rural children compared with winter and fall. Butyrylcholinesterase was depressed in rural children in fall compared with spring and summer. Adjustment for insecticide exposure did not affect these associations.

Conclusions: Environmental exposures to cholinesterase-inhibiting insecticides have measurable biochemical effects on blood cholinesterases in rural children from farmworker families.

目的:在两组前瞻性设计中,本研究比较了农村农场工人家庭中拉丁裔儿童和可比城市儿童的季节性胆碱酯酶水平,以评估环境暴露于胆碱酯酶抑制杀虫剂的影响。方法:每季度采集8岁儿童(74名农村儿童,62名城市儿童)2年以上的血液样本和被动剂量计腕带。实验室分析评估了血液样本中的总胆碱酯酶(total ChE)、乙酰胆碱酯酶(AChE)和丁酰胆碱酯酶(BChE),以及腕带中的杀虫剂。结果:与冬季和秋季相比,春季和夏季农村儿童的总ChE和AChE水平下降。与春季和夏季相比,秋季农村儿童的BChE较低。杀虫剂暴露量的调整并没有影响这些关联。结论:环境暴露于胆碱酯酶抑制剂对来自农场工人家庭的农村儿童的血胆碱酯酶具有可测量的生化影响。
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引用次数: 0
Do Sleep Problems Explain the Association Between Work Stress and the Trajectories of Work Ability From Midlife to Pensionable Age? 从中年到退休年龄,睡眠问题能解释工作压力和工作能力轨迹之间的关系吗?
IF 3.2 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-12-01 Epub Date: 2023-08-28 DOI: 10.1097/JOM.0000000000002954
Marika Kontturi, Prakash Kc, Jenni Ervasti, Jaana Pentti, Saana Myllyntausta, Petri Karkkola, Kirsi Honkalampi, Jussi Vahtera, Sari Stenholm, Marianna Virtanen

Objective: This study examined whether mid-life work stress, defined as job strain and effort-reward imbalance (ERI), predicts work ability trajectories observed 12 years preceding the individual pensionable age. In addition, the role of sleep problems as a mediator in these associations was examined.

Methods: Survey data were collected from 2707 Finnish municipal employees.

Results: Identified work ability trajectories were "stable excellent," "stable good," "moderate," and "low decreasing." Baseline job strain and ERI were associated with a greater likelihood of belonging to impaired work ability trajectories when compared with "stable good" trajectory. Baseline sleep problems explained the association of job strain by 38% and of ERI by 54%.

Conclusions: Mid-life work stress is associated with work ability in the last years preceding pensionable age. Sleep problems might be a potential mediator in these associations.

目的:本研究考察了中年工作压力(定义为工作压力和努力-回报失衡(ERI))是否能预测个人退休年龄前12年的工作能力轨迹。此外,研究人员还研究了睡眠问题在这些关联中的中介作用。方法:对2707名芬兰市政雇员进行调查。结果:确定的工作能力轨迹为“稳定优秀”、“稳定良好”、“中等”和“低下降”。与“稳定良好”的工作轨迹相比,基线工作压力和ERI更有可能属于受损的工作能力轨迹。基线睡眠问题解释了38%的工作压力和54%的ERI的关联。结论:中年工作压力与退休年龄前几年的工作能力有关。睡眠问题可能是这些关联的潜在中介。
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引用次数: 0
A Study on Vascular Regulators as Early Biomarkers of Hand Arm Vibration Syndrome. 血管调节因子作为手臂振动综合征早期生物标志物的研究。
IF 3.2 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-12-01 Epub Date: 2023-09-01 DOI: 10.1097/JOM.0000000000002957
Hongyu Yang, Ziyu Chen, Xiuwen Hu, Nuoyan Wei, Jiajie Li, Yuan Wei, Qingsong Chen

Objectives: Purposes of this study are to study the changes in expression of vascular regulators after vibration exposure and during the onset of vibration-induced white finger (VWF) and to screen for vascular regulatory factors that could be used as early biomarkers of HAVS.

Methods: Using judgmental sampling from a Chinese factory, workers with VWF and hand-transmitted vibration exposure but without VWF were selected for research. Blood samples were taken from all subjects, and the levels of nine of the vascular regulators were measured using ELISA.

Results: Receiver operating characteristic curve analysis was performed on nine vascular regulators to assess their diagnostic sensitivity for VWF with the following area under the curve results: PGI 2 = 0.861, ANP = 0.840.

Conclusions: Collectively, PGI 2 and ANP exhibited the most potential for the early diagnosis of HAVS.

目的:研究振动暴露后和振动诱发白指(VWF)发病过程中血管调节因子的表达变化,筛选可作为HAVS早期生物标志物的血管调节因子。方法:采用中国某工厂的判断抽样方法,选取有VWF和手传振动暴露但无VWF的工人进行研究。从所有受试者身上采集血液样本,用ELISA法测定9种血管调节因子的水平。结果:对9种血管调节剂进行受试者工作特征曲线分析,评价其对VWF的诊断敏感性,曲线下面积:PGI 2 = 0.861, ANP = 0.840。结论:总的来说,PGI 2和ANP在HAVS的早期诊断中最有潜力。
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引用次数: 0
Perceived Workplace Health Support and Severe Psychological Distress Among Japanese Workers: A Prospective Cohort Study. 日本员工对工作场所健康支持与严重心理困扰的认知:一项前瞻性队列研究。
IF 3.2 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-12-01 Epub Date: 2023-07-28 DOI: 10.1097/JOM.0000000000002936
Kazunori Ikegami, Hajime Ando, Kazushirou Kurogi, Akira Ogami

Objective: This study aimed to assess the extent to which the intensity of perceived workplace health support (PWHS) affected the incidence of psychological distress.

Methods: At the baseline, data from 4540 eligible participants throughout Japan were obtained using an Internet survey. Among them, 2362 participants who could be followed up 1 year after the initial study were included in the analysis. The intensity of PWHS was determined using an original questionnaire. Psychological distress was assessed using the Kessler Psychological Distress Scale.

Results: Participants with high PWHS were less likely to experience severe psychological distress than those with low PWHS even after adjusting for confounding factors including work-related factors. The incidence of severe psychological distress decreased as the intensity of PWHS increased.

Conclusions: Enhanced PWHS reduced psychological distress and positively affected workers' mental health.

目的:本研究旨在评估感知工作场所健康支持(PWHS)强度对心理困扰发生率的影响程度。方法:在基线时,通过网络调查获得来自日本4540名符合条件的参与者的数据。其中,2362名在初始研究后可随访1年的参与者被纳入分析。PWHS的强度由原始问卷确定。采用Kessler心理困扰量表评估心理困扰。结果:高PWHS的参与者比低PWHS的参与者更不可能经历严重的心理困扰,即使在调整混杂因素包括工作因素后。重度心理困扰的发生率随PWHS强度的增加而降低。结论:增强PWHS可减少员工的心理困扰,对员工的心理健康有积极影响。
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引用次数: 0
Cluster Analysis of World Trade Center Related Lower Airway Diseases. 世贸中心相关下呼吸道疾病的聚类分析。
IF 3.2 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-11-29 DOI: 10.1097/jom.0000000000003023
Rafael E de la Hoz, Yunho Jeon, John T Doucette, Anthony P Reeves, Raúl San José Estépar, Juan C Celedón
Introduction: Cluster analysis can classify without a priori assumptions the heterogeneous chronic lower airway diseases found in former workers at the World Trade Center (WTC) disaster site. Methods: We selected the first available chest computed tomography scan with quantitative computed tomography measurements on 311 former WTC workers with complete clinical, and spirometric data from their closest surveillance visit. We performed a nonhierarchical iterative algorithm K-prototype cluster analysis, using gap measure. Results: A five-cluster solution was most satisfactory. Cluster 5 had the healthiest individuals. In cluster 4, smoking was most prevalent and intense but there was scant evidence of respiratory disease. Cluster 3 had symptomatic subjects with reduced forced vital capacity impairment (low FVC). Clusters 1 and 2 had less dyspneic subjects, but more functional and quantitative computed tomography evidence of chronic obstructive pulmonary disease (COPD) in cluster 1, or low FVC in cluster 2. Clusters 1 and 4 had the highest proportion of rapid first-second forced expiratory volume decliners. Conclusions: Cluster analysis confirms low FVC and COPD/pre-COPD as distinctive chronic lower airway disease phenotypes on long-term surveillance of the WTC workers.
简介聚类分析可以在没有先验假设的情况下对世贸中心(WTC)灾难现场前工作人员中发现的异质性慢性下呼吸道疾病进行分类。方法:我们选取了第一份可获得的胸部计算机断层扫描图像,并对 311 名前世贸中心工人进行了定量计算机断层扫描测量,这些工人在最近的监测访问中提供了完整的临床和肺活量数据。我们使用差距测量法进行了非层次迭代算法 K 原型聚类分析。结果显示五个聚类的解决方案最令人满意。第 5 组的人最健康。在第 4 组中,吸烟最为普遍和严重,但很少有呼吸系统疾病的证据。第 3 组的受试者有症状,用力呼吸量减少(FVC 低)。第 1 组和第 2 组有较少呼吸困难的受试者,但第 1 组有较多慢性阻塞性肺病(COPD)的功能性和定量计算机断层扫描证据,第 2 组有较低的 FVC。第 1 组和第 4 组第一秒用力呼气量快速下降者的比例最高。结论:聚类分析证实,在对 WTC 工人的长期监测中,低 FVC 和慢性阻塞性肺病/慢性阻塞性肺病前期是独特的慢性下气道疾病表型。
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引用次数: 0
Impact of Hurricane Harvey on Inpatient Asthma Hospitalization Visits Within Southeast Texas, 2016-2019. 飓风哈维对2016-2019年德克萨斯州东南部哮喘住院患者住院就诊的影响。
IF 3.2 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-11-01 Epub Date: 2023-07-25 DOI: 10.1097/JOM.0000000000002928
Yiyao Li, Justin Buendia, Sabeena Sears, Mirela Ibrahimovic, Heather Bertero, Rachel Wiseman, Nimisha Bhakta

Objective: The aim of the study is to estimate inpatient asthma hospital visit rates among impacted Texans in Public Health Region 6/5S during the year of and after Hurricane Harvey.

Methods: Asthma inpatient hospitalization discharges were collected from the Texas Health Care Information Collection database (2016-2019).

Results: Females (age-adjusted rates [AARs] = 4.8-5.0) and Black Texans (AARs = 5.0-8.1) experienced significantly higher AARs compared with males and White Texans during the year of and after Harvey. During the year of Hurricane Harvey, females were 1.49 times as likely to have an inpatient asthma visit compared with males, while Black Texans were 2.78 times as likely to have an inpatient asthma hospitalization compared with White Texans.

Conclusions: Findings from this study may assist public health professionals and local officials to allocate future resources to the most impacted subgroups as well as establish effective processes to mitigate consequences.

目的:本研究的目的是估计飓风哈维前后6/5S公共卫生区受影响得克萨斯人的哮喘住院就诊率。方法:从得克萨斯州卫生保健信息收集数据库(2016-2019)中收集哮喘住院出院人数。结果:女性(年龄调整率[ARS]=4.8-5.0)和黑人得克萨斯人(AARs=5.0-8.1)与男性和德克萨斯白人相比,在哈维出生前后经历了显著更高的AARs。在飓风“哈维”期间,女性哮喘住院就诊的可能性是男性的1.49倍,而得克萨斯黑人住院治疗哮喘的可能性是得克萨斯白人的2.78倍。结论:这项研究的结果可能有助于公共卫生专业人员和地方官员将未来的资源分配给受影响最严重的亚组,并建立有效的程序来减轻后果。
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引用次数: 0
Determinants of Sickness Absence Duration After Mild COVID-19 in a Prospective Cohort of Canadian Healthcare Workers. 加拿大医疗工作者前瞻性队列中轻度新冠肺炎后疾病缺席时间的决定因素。
IF 3.2 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-11-01 Epub Date: 2023-08-12 DOI: 10.1097/JOM.0000000000002945
Anil Adisesh, Quentin Durand-Moreau, France Labrèche, Shannon Ruzycki, Tanis Zadunayski, Nicola Cherry

Objective: The aim of the study is to identify modifiable factors associated with sickness absence duration after a COVID-19 infection.

Methods: Participants in a prospective cohort of 4964 Canadian healthcare workers were asked how many working days they had missed after a positive COVID-19 test. Only completed episodes with absence ≤31 working day and no hospital admission were included. Cox regression estimated the contribution of administrative guidelines, vaccinations, work factors, personal characteristics, and symptom severity.

Results: A total of 1520 episodes of COVID-19 were reported by 1454 participants. Days off work reduced as the pandemic progressed and were fewer with increasing numbers of vaccines received. Time-off was longer with greater symptom severity and shorter where there was a provision for callback with clinical necessity.

Conclusions: Vaccination, an important modifiable factor, related to shorter sickness absence. Provision to recall workers at time of clinical need reduced absence duration.

目的:本研究旨在确定新冠肺炎感染后与病假时间相关的可改变因素。方法:在一个由4964名加拿大医护人员组成的前瞻性队列中,参与者被问及他们在新冠肺炎检测呈阳性后错过了多少工作日。仅包括缺勤≤31个工作日且无住院的已完成发作。Cox回归估计了管理指南、疫苗接种、工作因素、个人特征和症状严重程度的影响。结果:1454名参与者共报告了1520例新冠肺炎发作。随着疫情的发展,休息日减少了,随着接种疫苗数量的增加,休息日也减少了。症状严重程度越高,休息时间越长,在有临床必要的情况下,休息时间更短。结论:疫苗接种是一个重要的可改变因素,与较短的病假时间有关。在临床需要时召回工作人员的规定缩短了缺勤时间。
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引用次数: 0
Book Review "the IBM COVID-19 Compendium". 《IBM新冠肺炎简编》书评。
IF 3.2 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-11-01 Epub Date: 2023-08-10 DOI: 10.1097/JOM.0000000000002946
Lydia Boyd Campbell, Vanessa Burrowes, Robert L Quigley
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引用次数: 0
Residual Dialkyl Phosphate Metabolite Concentrations of Organophosphate Pesticides Among Indian Farmworkers: Implication of Exposure and Hazard Assessment. 印度农场工人中有机磷农药残留二烷基磷酸酯代谢产物浓度:暴露和危害评估的意义。
IF 3.2 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-11-01 Epub Date: 2023-09-02 DOI: 10.1097/JOM.0000000000002960
Summaiya Lari, Arun Pandiyan, Janardhan Vanka, Babban Jee, Praveen Yamagani, Senthil Balakrishnan Kumar, Mohan Naidu, Padmaja Jonnalagadda

Objective: Biomonitoring of urinary dialkyl phosphate (DAP) metabolites, a sensitive biomarker to assess pesticides exposure and also to study the impact of the use of personal protective equipment (PPE).

Methods: A preintervention-postintervention study to biomonitor dimethylphosphate, diethylphosphate, diethylthiophosphate, and diethyl-dithiophosphate using liquid chromatography with tandem mass spectrometry among Indian farmworkers (n = 120).

Results: Dimethylphosphate was detected in all samples at a mean concentration of 74.91 μg · L -1 (17.616 μg · g -1 creatinine), whereas diethylthiophosphate and diethyl-dithiophosphate were detected in 88% and 82% of samples, respectively, among farmworkers who adopted unsafe pesticide-handling practices. Intervention studies showed a significant reduction in the urinary DAP metabolites detected among the farmworkers using PPE provided to them ( P < 0.01).

Conclusions: Study confirms the exposure to pesticides among farmworkers and highlights the importance of the use of PPE to minimize exposure.

目的:对尿磷酸二烷基酯(DAP)代谢产物进行生物监测,DAP是一种敏感的生物标志物,用于评估农药暴露情况,并研究使用个人防护装备(PPE)的影响,结果:在所有样本中检测到二甲基磷酸盐,平均浓度为74.91μg·L-1(17.616μg·g-1肌酸酐),而在88%和82%的样本中分别检测到二乙基硫代磷酸盐和二乙基二硫代磷酸盐,在采用不安全农药处理方法的农场工人中。干预研究显示,在使用提供给他们的个人防护装备的农场工人中,检测到的尿DAP代谢产物显著减少(P<0.01)。结论:研究证实了农场工人接触农药的情况,并强调了使用个人防护装备以尽量减少接触的重要性。
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引用次数: 0
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Journal of Occupational and Environmental Medicine
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