Journal of orthopaedics最新文献

{"title":"Injury patterns in footvolley players: an epidemiological survey","authors":"Rodrigo Favarin Pozzobom ,&nbsp;Tamiris Beppler Martins ,&nbsp;Filippo Migliorini ,&nbsp;Nicola Maffulli ,&nbsp;Rodrigo Okubo","doi":"10.1016/j.jor.2025.12.066","DOIUrl":"10.1016/j.jor.2025.12.066","url":null,"abstract":"<div><h3>Background</h3><div>Footvolley, a fusion of football and volleyball, has gained considerable popularity worldwide. The dynamic nature of the sport exposes players to various risks of injury. This study investigates the prevalence of injuries among footvolley athletes. It examines practitioner profiles and associated injuries and identifies the anatomical regions most commonly affected.</div></div><div><h3>Material and methods</h3><div>The study sample comprised footvolley players from Brazil, encompassing individuals of both genders aged 18 and above, with no restrictions on practice duration, to provide a comprehensive overview of player profiles within the sport. Data was collected using a customised form created in Google Forms®, which was disseminated via email, WhatsApp®, and social media platforms and distributed in training centres and to individual practitioners. The study population predominantly consisted of male participants, with an average age of 30.</div></div><div><h3>Results</h3><div>182 injuries were reported, resulting in an overall injury incidence rate of 1.43 per 1000 h of exposure. Notably, 52.3 % of practitioners experienced some form of injury related to footvolley practice. The anatomical segments most commonly affected were the knees, lumbar spine, neck, and ankles. Furthermore, the recurrence rate for all injuries was 21.5 %. Several factors were associated with a higher prevalence of injuries, including older age, increased experience and practice in footvolley, participation in competitions, and not engaging in simultaneous training in another modality.</div></div><div><h3>Conclusions</h3><div>This study sheds light on the injury landscape in footvolley and underscores the importance of implementing targeted injury prevention strategies and promoting athlete well-being in this dynamic sport.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"74 ","pages":"Pages 174-178"},"PeriodicalIF":1.5,"publicationDate":"2026-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145927814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design-dependent associations between quadriceps strength and sagittal knee biomechanics after posterior-stabilized total knee arthroplasty: A 3D motion analysis study","authors":"Ryota Fujii ,&nbsp;Hyunho Lee ,&nbsp;Christopher Stickley ,&nbsp;Kazuyoshi Nakanishi","doi":"10.1016/j.jor.2026.01.005","DOIUrl":"10.1016/j.jor.2026.01.005","url":null,"abstract":"<div><h3>Purpose</h3><div>Single-radius (SR) and multi-radius (MR) femoral components are widely used in posterior-stabilized total knee arthroplasty (TKA). While previous studies have compared these designs primarily using clinical outcomes or basic kinematics, the relationship between quadriceps strength and dynamic sagittal-plane knee biomechanics remains insufficiently understood.</div></div><div><h3>Methods</h3><div>This prospective exploratory cohort study included 31 posterior-stabilized TKAs (SR: 16 knees; MR: 15 knees). Patients were evaluated at 6 months and 1 year postoperatively. Knee extension strength was measured using a handheld dynamometer. Sagittal-plane biomechanics during level walking, stair ascent, and stair descent were assessed using three-dimensional motion capture. External knee flexion moment (KFM) and KFM impulse were calculated. Associations between quadriceps strength and sagittal-plane biomechanical variables were analyzed using Spearman correlation coefficients.</div></div><div><h3>Results</h3><div>No significant between-group differences were observed in demographics or clinical activity levels. In the SR group, no significant associations were identified between quadriceps strength and sagittal-plane biomechanical variables at any postoperative time point. In contrast, the MR group demonstrated a moderate positive correlation between knee extensor strength and stair-descent knee flexion moment (KFM) impulse at 6 months postoperatively (r = 0.498, p &lt; 0.05), which was not observed at 1 year postoperatively. During stair ascent, a significant positive correlation between knee extensor strength and the first peak KFM was observed in the MR group at 1 year (r = 0.606, p &lt; 0.05).</div></div><div><h3>Conclusions</h3><div>This exploratory study demonstrated design-dependent associations between quadriceps strength and sagittal-plane knee biomechanics after posterior-stabilized TKA. While no significant between-group differences were observed in clinical or absolute biomechanical outcomes, task- and time-dependent strength–biomechanics associations were identified in the MR group, whereas no such associations were observed in the SR group, suggesting potential clinical relevance in patients with delayed quadriceps recovery.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"74 ","pages":"Pages 179-185"},"PeriodicalIF":1.5,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145978365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"METTL14 regulate LRIG1 expression via m6A to affect nucleus pulposus cell senescence in intervertebral disc degeneration","authors":"Ruihai Xiao ,&nbsp;Qunying Yang ,&nbsp;Yingqun Yin ,&nbsp;Shanshan Peng ,&nbsp;Xigao Cheng","doi":"10.1016/j.jor.2026.01.004","DOIUrl":"10.1016/j.jor.2026.01.004","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aims to explore the role of METTL14, a key m6A “writer” in regulating LRIG1 expression and its involvement in IVDD pathogenesis.</div></div><div><h3>Methods</h3><div>METTL14 expression was evaluated in nucleus pulposus (NP) tissues from IVDD patients at different degeneration stages using immunohistochemistry. In vitro experiments were conducted with METTL14 knockdown and TNF-α-induced cellular degeneration in NP cells. The effects on cellular senescence markers, ECM components, and m6A RNA methylation were examined. m6A RNA immunoprecipitation was employed to assess m6A modification levels. Bioinformatics tools predicted potential m6A sites on LRIG1 mRNA, which were further validated by luciferase reporter assays.</div></div><div><h3>Results</h3><div>METTL14 expression was significantly upregulated in NP tissues from patients with severe IVDD. METTL14 knockdown in NP cells led to reduced m6A enrichment on LRIG1 mRNA, destabilizing LRIG1 transcripts and increasing cellular senescence marker P21. TNF-α stimulation further induced METTL14 expression, exacerbated ECM degradation, and accelerated cellular senescence. Restoration of LRIG1 expression through overexpression mitigated the degenerative changes caused by METTL14 knockdown. Luciferase assays confirmed that METTL14 regulates LRIG1 mRNA stability via specific m6A sites, establishing a METTL14-LRIG1 axis in cellular senescence.</div></div><div><h3>Conclusions</h3><div>This study identifies METTL14 as a critical regulator of LRIG1-mediated ECM stability and cellular senescence in IVDD pathogenesis. The METTL14-LRIG1 axis, driven by m6A modifications, provides new mechanistic insights into the inflammatory and degenerative processes underlying IVDD. Targeting METTL14 or the associated m6A pathway may offer novel therapeutic strategies for IVDD.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"74 ","pages":"Pages 195-204"},"PeriodicalIF":1.5,"publicationDate":"2026-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145978364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Legal blindness as a risk factor for complications and prolonged hospitalization after spinal fusion","authors":"Donald MacElroy ,&nbsp;Jay B. Ayar ,&nbsp;Samir Rao ,&nbsp;Merritt D. Kinon","doi":"10.1016/j.jor.2026.01.001","DOIUrl":"10.1016/j.jor.2026.01.001","url":null,"abstract":"<div><h3>Introduction</h3><div>Legally blind patients represent a vulnerable group who may face barriers to safe mobility, postoperative rehabilitation, and discharge planning. There is limited evidence describing perioperative course during spinal fusion surgery in this population. This study aimed to evaluate the association between legal blindness, operative complications and discharge disposition in patients undergoing cervical or lumbar spinal fusion.</div></div><div><h3>Methods</h3><div>The National Inpatient Sample was queried from 2016 to 2021, identifying adult hospitalizations for cervical or lumbar spinal fusion using ICD-10 procedure codes. The primary exposure was legal blindness (ICD-10-CM: H54.8). Outcomes included: major medical complications, non-home discharge and extended length of stay (&gt;3 days). Survey-weighted logistic regression was used to evaluate associations between legal blindness and complications.</div></div><div><h3>Results</h3><div>Among 338,578 hospitalizations for cervical or lumbar spinal fusion that met our inclusion criteria, 315 involved legally blind patients. In multivariate analysis adjusting for demographics, comorbidities and hospital level covariates, legal blindness was independently associated with higher odds of major medical complications (aOR 1.58, 95 % CI 1.08–2.32), non-home discharge (aOR 2.57, 95 % CI 1.98–3.32), and extended length of stay (aOR 1.67, 95 % CI 1.31–2.12).</div></div><div><h3>Conclusions</h3><div>Legal blindness is independently associated with increased major medical complications, extended hospital stays and higher rates of non-home discharge following spinal fusion procedures. These findings highlight the importance of recognizing visual impairment as a marker of perioperative vulnerability in the context of spinal fusion surgery and highlight the need for targeted perioperative strategies to support this underrepresented population.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"74 ","pages":"Pages 152-156"},"PeriodicalIF":1.5,"publicationDate":"2026-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145927805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A decade of progress and paradigm shifts in osteoporosis therapeutics: A bibliometric analysis","authors":"Yanping Liu,&nbsp;Xijie Yu","doi":"10.1016/j.jor.2025.12.069","DOIUrl":"10.1016/j.jor.2025.12.069","url":null,"abstract":"<div><div>Despite extensive research on osteoporosis therapies, systematic analysis of knowledge evolution and translational bottlenecks remains unexplored. This study presents the multidimensional bibliometric analysis of 10,247 publications (2015–2024) to decode paradigm shifts in osteoporosis therapeutics. Using CiteSpace and VOSviewer for bibliometric and visualization analyses, we observed a notable increase in annual publications, peaking in 2022. China and the United States led in research output, while European countries demonstrated higher citation impact. Shanghai Jiao Tong University, Harvard Medical School, and Chinese Academy of Sciences were the top three contributing institutions. Cooper, Cyrus is the most influential author. In academic publishing, <em>Osteoporosis International</em> has been identified as the journal with the most research results in the field of osteoporosis treatment. Keyword emergence analysis revealed a transition in research focus from randomized controlled trial and ovariectomized rats to drug, discontinuation, osteogenesis, bisphosphonate related osteonecrosis, network pharmacology, molecular docking, reduction, fixation, damage, American association, osteoporotic fracture, gut microbiota in the last five years, and that this is being explored in detail for future work. In summary, this study offers a thorough bibliometric analysis of osteoporosis therapeutics worldwide, providing scholars conducting analogous research in this field with valuable insights.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"74 ","pages":"Pages 104-112"},"PeriodicalIF":1.5,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145882593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of surgical procedure and radiographic hip alignment with hip abductor strength ratio at discharge after proximal femoral fracture surgery","authors":"Satoshi Hakukawa,&nbsp;Shunsuke Onuma,&nbsp;Kanata Yoshihara","doi":"10.1016/j.jor.2025.12.068","DOIUrl":"10.1016/j.jor.2025.12.068","url":null,"abstract":"<div><h3>Background</h3><div>Hip abductor weakness is common after proximal femoral fracture and may contribute to gait instability. The influence of postoperative hip alignment on early recovery of hip abductor strength during inpatient rehabilitation after surgery remains unclear.</div></div><div><h3>Objective</h3><div>To examine longitudinal changes in hip abductor strength and identify factors associated with the operated-to-non-operated hip abductor strength ratio at discharge, focusing on surgical procedure and radiographic alignment.</div></div><div><h3>Methods</h3><div>This retrospective observational cohort study enrolled 64 patients transferred to a rehabilitation hospital after proximal femoral fracture surgery (34 femoral neck fractures treated with hemiarthroplasty; 30 intertrochanteric fractures treated with cephalomedullary nailing). Hip abductor strength was measured using a handheld dynamometer at rehabilitation admission and discharge and normalized by body weight. Radiographic parameters were measured on supine anteroposterior pelvic radiographs; side-to-side differences (operated minus non-operated) were calculated for the neck–shaft angle, hip center of rotation, femoral offset, and trochanteric height. Multivariable linear regression (ANCOVA-type) was performed with the discharge strength ratio as the dependent variable and the admission strength ratio as an adjustment factor.</div></div><div><h3>Results</h3><div>Hip abductor strength improved on both sides (p &lt; 0.001). The operated side increased from 1.04 ± 0.5 to 1.8 ± 0.7 N/kg and the non-operated side from 1.6 ± 0.6 to 2.3 ± 0.8 N/kg; the operated-to-non-operated ratio improved from 62.7 % to 72.9 %. In the adjusted model (R² = 0.325), cephalomedullary nailing (vs hemiarthroplasty) was associated with a higher discharge strength ratio (B = 0.114, p = 0.027). A greater neck–shaft angle difference was also associated with a higher discharge strength ratio (B = 0.0073 per degree, p = 0.011). The admission strength ratio remained a significant predictor (B = 0.245, p = 0.002).</div></div><div><h3>Conclusions</h3><div>Early recovery of the hip abductor strength ratio after proximal femoral fracture was associated with surgical procedure and postoperative neck–shaft angle asymmetry, independent of baseline strength ratio. Postoperative radiographic alignment may aid in stratifying recovery and tailoring rehabilitation, although causal inference is limited.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"74 ","pages":"Pages 131-137"},"PeriodicalIF":1.5,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145927816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for mortality in patients following total hip arthroplasty and hemiarthroplasty due to femoral neck fractures","authors":"Itay Ron ,&nbsp;Lizi Tamam ,&nbsp;Bezalel Peskin ,&nbsp;Nabil Ghrayeb ,&nbsp;Doron Norman ,&nbsp;Jacob Shapira","doi":"10.1016/j.jor.2025.12.067","DOIUrl":"10.1016/j.jor.2025.12.067","url":null,"abstract":"<div><h3>Background</h3><div>Femoral neck fractures (FNF) in older adults are frequently managed with either total hip arthroplasty (THA) or hemiarthroplasty (HA). Despite improvements in surgical techniques, mortality rates after hip fracture surgery remain high. Identifying predictors of early mortality may enhance surgical decision-making, optimize perioperative management, and improve patient outcomes.</div></div><div><h3>Purpose</h3><div>The purpose of this study was to determine the short- and mid-term mortality rates after THA and HA for FNF, to identify clinical, demographic, and laboratory factors associated with 30-, 90-, and 180-day mortality, and to establish clinically relevant cutoff thresholds for significant continuous variables to stratify risk.</div></div><div><h3>Patients and methods</h3><div>We retrospectively reviewed 2379 consecutive patients treated for sub-capital FNF at a tertiary trauma center between [insert study years]. Of these, 831 underwent THA and 1548 underwent HA. Mortality was assessed at 30, 90, and 180 days postoperatively. Demographic, clinical, and laboratory parameters were analyzed using univariate and multivariate logistic regression models. Receiver operating characteristic (ROC) curve analysis was performed to identify optimal cutoff thresholds for significant continuous predictors.</div></div><div><h3>Results</h3><div>Among THA patients, mortality was 1.4 % at 30 days, 3.4 % at 90 days, and 5.1 % at 180 days. Postoperative albumin ≤2.85 g/dL predicted 30-day mortality, while C-reactive protein (CRP) &gt; 19.15 mg/dL was independently associated with mortality at 90 and 180 days. Among HA patients, mortality was 6.6 % at 30 days, 12.9 % at 90 days, and 17.6 % at 180 days. Predictors of 30-day mortality included white blood cell count (WBC) &gt; 14.48 × 10⁹/L, albumin &lt;3.55 g/dL, and Charlson Comorbidity Index (CCI) &gt; 7.5. At 90 and 180 days, age &gt;83.65 and &gt; 89.34 years, WBC &gt;13.49 × 10⁹/L, albumin &lt;3.35–3.45 g/dL, creatinine &gt;1.08 mg/dL, and CCI &gt;6.5 were associated with higher mortality risk.</div></div><div><h3>Conclusions</h3><div>This study identified several laboratory and clinical markers that predict short- and mid-term mortality following hip arthroplasty for FNF. Hypoalbuminemia, elevated inflammatory markers, renal dysfunction, and high comorbidity burden were consistent risk factors. Incorporating these parameters into preoperative assessment may improve patient selection, perioperative optimization, and shared decision-making.</div></div><div><h3>Level of Evidence</h3><div>III</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"74 ","pages":"Pages 124-130"},"PeriodicalIF":1.5,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145927804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review and meta-analysis of cases of prosthetic hip-associated cobalt toxicity in patients with prosthetic hip ceramic bearing fractures subsequently revised to metal-on-polyethylene implants","authors":"Patrick Sweeney ,&nbsp;James Broderick","doi":"10.1016/j.jor.2025.12.064","DOIUrl":"10.1016/j.jor.2025.12.064","url":null,"abstract":"<div><h3>Background</h3><div>Prosthetic hip-associated cobalt toxicity (PHACT) remains a rare but serious complication, potentially leading to missed diagnoses and delayed treatment. This systematic review explores cases of PHACT associated with fractured ceramic bearing followed by revision surgery with metal-on-polyethylene implants. Notably, patients in this subgroup often exhibited earlier symptom onset and elevated cobalt ion levels. Through a systematic review, we aim to explore and summarise the most common symptoms and clinical outcomes associated with PHACT among this specific patient subgroup. Our focus is on identifying patterns of systemic symptoms and associated clinical outcomes.</div></div><div><h3>Methods</h3><div>Adhering to PRISMA guidelines, we conducted a structured search across PubMed, Medline, and Scopus databases. Inclusion criteria comprised published case reports or case series detailing PHACT cases after ceramic bearing fractures revised to metal-on-polyethylene bearings. Over 30 cases were identified, and their clinical presentations and outcomes were analysed.</div></div><div><h3>Result</h3><div>The majority of PHACT cases in this cohort presented with cardiovascular manifestations (cardiomyopathy, cardiogenic shock, and heart failure), neurological symptoms (visual impairment, sensorineural hearing loss, and cognitive impairment), and endocrine dysfunction (thyroid dysfunction). Various atypical symptoms were also observed.</div></div><div><h3>Conclusion</h3><div>PHACT within this patient group presents insidiously with diverse, sometimes overlapping, systemic symptoms. The study highlights the potential for missed diagnoses due to the lack of apparent risk factors or related medical history. This review strongly advocates for proactive, registry data-driven identification of at-risk patients, as well as the opportunity for follow-up assessment and cobalt level monitoring. This study also highlights the importance of ceramic-on-polyethylene based revision in cases of ceramic bearing fractures.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"74 ","pages":"Pages 113-123"},"PeriodicalIF":1.5,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145927803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global research trends and hotspots of rheumatoid arthritis and mitogen-activated protein kinase-a bibliometrics and visualization analysis","authors":"Jian Gao ,&nbsp;Jing Xu ,&nbsp;Hui Li ,&nbsp;Chong Gao","doi":"10.1016/j.jor.2025.12.065","DOIUrl":"10.1016/j.jor.2025.12.065","url":null,"abstract":"<div><h3>Background</h3><div>Rheumatoid arthritis (RA) is a common autoimmune disease characterized by synovial hyperplasia and bone erosion, which ultimately leads to joint deformity and disability. The mitogen-activated protein kinase (MAPK) signaling pathway is one of the critical pathways in eukaryotic cells involved in regulating cell mitosis, differentiation, and apoptosis, as well as inflammation and stress responses, and is closely related to the development of RA. Intra-articular cytokines in patients with RA can bind to the corresponding receptors and activate intracellular upstream modulators, which activate the MAPK signaling pathway in a tertiary enzyme-linked manner.</div></div><div><h3>Methods</h3><div>This study aimed to explore the research hotspots in the RA and MAPK signaling pathway research and the research focus and intrinsic connections by identifying the number of papers published annually, authors, institutions, keywords, and journals.</div></div><div><h3>Results</h3><div>Through bibliometric analyses, it was found that the number of publications surged from 2000 to 2023, and the number of publications in 2017 exceeded 100 articles/year for the first time; it was also the year with the most significant number of publications, the most considerable number of publications was from China, with 536 articles, and the second-ranked was from the United States, with 384 articles; and the most significant number of authors was from the University of California, USA, with Firestein, Gary s. professor, with 28 articles; the first institution with the most significant number of articles is univ calif san diego from the U.S.A., with 37 articles; in the keyword analysis, the frequency and centrality of the keywords are Nf kappa b (347, 0.04), Activation (231, 0.06), Activated protein kinase (211, 0.08), Gene expression (169, 0.09), Tumor necrosis factor (146, 0.07),The trend is still increasing, suggesting that many publications exploring this area will continue to be reported in the future.</div></div><div><h3>Conclusion</h3><div>This study will help scholars better understand the rheumatoid arthritis and mitogen-activated protein kinase of hotspots in this field and may provide some inspiration for research in this area.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"74 ","pages":"Pages 272-288"},"PeriodicalIF":1.5,"publicationDate":"2025-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146078725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of demographic and socioeconomic factors and urbanization status on postoperative outcomes following hip arthroscopy","authors":"Dev Dayal ,&nbsp;Maxwell Harrell ,&nbsp;Clay Rahaman ,&nbsp;Caleb Berta ,&nbsp;Joe Dekle ,&nbsp;Jeffrey C. Krout ,&nbsp;Eugene Brabston ,&nbsp;Walter Smith ,&nbsp;Thomas E. Evely ,&nbsp;Amit Momaya ,&nbsp;Aaron J. Casp","doi":"10.1016/j.jor.2025.12.061","DOIUrl":"10.1016/j.jor.2025.12.061","url":null,"abstract":"<div><h3>Introduction</h3><div>Hip arthroscopy (HA) is increasingly used to treat femoroacetabular impingement (FAI) and labral tears, with growing interest in the role of socioeconomic factors on postoperative outcomes. Prior literature suggests socioeconomic deprivation may worsen patient-reported outcomes (PROMs), but findings regarding the Area Deprivation Index (ADI) and urbanization status remain inconsistent. This study aimed to evaluate the difference in PROMs after HA secondary to symptomatic FAI and hip labral tears based on the residential urbanization status, demographic variables, and Area Deprivation Index (ADI) values of patients in our single-center cohort</div></div><div><h3>Methods</h3><div>A single-institution retrospective review was conducted on 86 patients who underwent HA between 2014 and 2023. Patients were categorized as urban or rural based on U.S. Census data and assigned national/state ADI scores based on their residential addresses. PROMs (mHHS, HOS-ADL, HOS-Sport, NAHS) were collected via telephone survey at ≥1 year postoperatively. Statistical comparisons and multivariable regression analyses were used to assess the impact of demographic variables and ADI on PROMs.</div></div><div><h3>Results</h3><div>There were no significant differences in PROMs between urban and rural patients. However, regression analysis revealed that national ADI and age were significantly negatively correlated with all PROMs (p &lt; 0.05). Older age and higher ADI independently predicted worse postoperative outcomes. Interaction effects, such as age × BMI or age × ADI, also negatively influenced certain PROMs. Race and surgical indication showed limited interaction effects.</div></div><div><h3>Conclusion</h3><div>While urbanization status did not impact outcomes, higher socioeconomic deprivation (as measured by national ADI) and increased age were associated with significantly worse PROMs after HA at 1-year follow-up. These findings suggest that neighborhood-level socioeconomic disadvantage plays a more critical role than urban-rural classification in influencing recovery. Strategies aimed at addressing social determinants of health may improve HA outcomes, particularly in socioeconomically disadvantaged populations.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"74 ","pages":"Pages 99-103"},"PeriodicalIF":1.5,"publicationDate":"2025-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145882552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}