Pub Date : 2026-04-01Epub Date: 2025-12-23DOI: 10.1016/j.jor.2025.12.054
Kris Hanby , Jeffrey Yergler , Patrick Aubin , Mouhanad M. El Othmani , Edward Stolarski , Steven Lyons
Background
Remote monitoring has been correlated to reduced acute care usage (emergency department (ED)) in cardiovascular, diabetes and COVID domains. Correspondingly, the use of smart implantable devices (SID) in total knee arthroplasty (TKA) may lead to reduced acute care usage in orthopedics.
Methods
Retrospective claims data from a nationally representative, third-party claims aggregator were analyzed for ED and hospital admission incidence and cumulative 90-day costs. Patients who received an SID were identified and matched 1:2 with patients who received a traditional knee prosthesis. A subgroup of patients with complete longitudinal claims data for days 91–365 were analyzed for cost comparisons. Chi-squared tests were used to compare acute care incidence and Wilcoxon rank sum tests were used to compare costs.
Results
The analysis included 1621 patients with SID knees (1709 TKAs) and 3041 patients (3418 TKAs) implanted with traditional knees. Cumulative incidence of ED visit (SID: 11.4 %; control: 15.6 %), hospital admission (SID: 6.0 %; control: 8.8 %), or any acute care (ED or hospital admission) (SID: 14.1 %; control: 19.2 %) was significantly lower in the SID group (p < 0.05). Median total cost of all healthcare services from the day after surgery to day 90 was significantly lower in the SID group ($3747) than the controls ($5629), representing 61 % of the cost of control patients. SID patients also had lower costs during day 91–365 ($5322 and $8,454, respectively).
Conclusion
Use of SIDs in primary TKA was associated with fewer ED visits and hospital admissions, as well as lower 90-day total healthcare costs. These cost reductions reflect both a lower incidence of unplanned care and lower costs per patient. These findings support the potential of implant-derived recovery data to enhance care coordination, align postoperative management with patient expectations, increase patient confidence in their health status and reduce the burden of post-TKA acute care.
{"title":"Smart implantable devices are associated with reduced 90-day acute care utilization and cost following total knee arthroplasty","authors":"Kris Hanby , Jeffrey Yergler , Patrick Aubin , Mouhanad M. El Othmani , Edward Stolarski , Steven Lyons","doi":"10.1016/j.jor.2025.12.054","DOIUrl":"10.1016/j.jor.2025.12.054","url":null,"abstract":"<div><h3>Background</h3><div>Remote monitoring has been correlated to reduced acute care usage (emergency department (ED)) in cardiovascular, diabetes and COVID domains. Correspondingly, the use of smart implantable devices (SID) in total knee arthroplasty (TKA) may lead to reduced acute care usage in orthopedics.</div></div><div><h3>Methods</h3><div>Retrospective claims data from a nationally representative, third-party claims aggregator were analyzed for ED and hospital admission incidence and cumulative 90-day costs. Patients who received an SID were identified and matched 1:2 with patients who received a traditional knee prosthesis. A subgroup of patients with complete longitudinal claims data for days 91–365 were analyzed for cost comparisons. Chi-squared tests were used to compare acute care incidence and Wilcoxon rank sum tests were used to compare costs.</div></div><div><h3>Results</h3><div>The analysis included 1621 patients with SID knees (1709 TKAs) and 3041 patients (3418 TKAs) implanted with traditional knees. Cumulative incidence of ED visit (SID: 11.4 %; control: 15.6 %), hospital admission (SID: 6.0 %; control: 8.8 %), or any acute care (ED or hospital admission) (SID: 14.1 %; control: 19.2 %) was significantly lower in the SID group (p < 0.05). Median total cost of all healthcare services from the day after surgery to day 90 was significantly lower in the SID group ($3747) than the controls ($5629), representing 61 % of the cost of control patients. SID patients also had lower costs during day 91–365 ($5322 and $8,454, respectively).</div></div><div><h3>Conclusion</h3><div>Use of SIDs in primary TKA was associated with fewer ED visits and hospital admissions, as well as lower 90-day total healthcare costs. These cost reductions reflect both a lower incidence of unplanned care and lower costs per patient. These findings support the potential of implant-derived recovery data to enhance care coordination, align postoperative management with patient expectations, increase patient confidence in their health status and reduce the burden of post-TKA acute care.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"74 ","pages":"Pages 289-295"},"PeriodicalIF":1.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146078073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-04-01Epub Date: 2026-01-07DOI: 10.1016/j.jor.2026.01.005
Ryota Fujii , Hyunho Lee , Christopher Stickley , Kazuyoshi Nakanishi
Purpose
Single-radius (SR) and multi-radius (MR) femoral components are widely used in posterior-stabilized total knee arthroplasty (TKA). While previous studies have compared these designs primarily using clinical outcomes or basic kinematics, the relationship between quadriceps strength and dynamic sagittal-plane knee biomechanics remains insufficiently understood.
Methods
This prospective exploratory cohort study included 31 posterior-stabilized TKAs (SR: 16 knees; MR: 15 knees). Patients were evaluated at 6 months and 1 year postoperatively. Knee extension strength was measured using a handheld dynamometer. Sagittal-plane biomechanics during level walking, stair ascent, and stair descent were assessed using three-dimensional motion capture. External knee flexion moment (KFM) and KFM impulse were calculated. Associations between quadriceps strength and sagittal-plane biomechanical variables were analyzed using Spearman correlation coefficients.
Results
No significant between-group differences were observed in demographics or clinical activity levels. In the SR group, no significant associations were identified between quadriceps strength and sagittal-plane biomechanical variables at any postoperative time point. In contrast, the MR group demonstrated a moderate positive correlation between knee extensor strength and stair-descent knee flexion moment (KFM) impulse at 6 months postoperatively (r = 0.498, p < 0.05), which was not observed at 1 year postoperatively. During stair ascent, a significant positive correlation between knee extensor strength and the first peak KFM was observed in the MR group at 1 year (r = 0.606, p < 0.05).
Conclusions
This exploratory study demonstrated design-dependent associations between quadriceps strength and sagittal-plane knee biomechanics after posterior-stabilized TKA. While no significant between-group differences were observed in clinical or absolute biomechanical outcomes, task- and time-dependent strength–biomechanics associations were identified in the MR group, whereas no such associations were observed in the SR group, suggesting potential clinical relevance in patients with delayed quadriceps recovery.
目的单桡骨(SR)和多桡骨(MR)股骨假体广泛应用于后稳定全膝关节置换术(TKA)。虽然先前的研究主要通过临床结果或基本运动学来比较这些设计,但股四头肌力量和动态矢状面膝关节生物力学之间的关系仍然没有得到充分的了解。方法本前瞻性探索性队列研究纳入31例后稳定tka患者(SR: 16膝;MR: 15膝)。分别于术后6个月和1年对患者进行评估。使用手持式测力仪测量膝关节伸展强度。使用三维运动捕捉技术评估水平行走、楼梯上升和楼梯下降时的矢状面生物力学。计算膝关节外屈力矩(KFM)和KFM冲量。使用Spearman相关系数分析股四头肌力量与矢状面生物力学变量之间的关系。结果两组在人口统计学和临床活动水平上无显著差异。在SR组中,在任何术后时间点,股四头肌力量和矢状面生物力学变量之间没有明显的关联。相比之下,MR组在术后6个月时膝关节伸肌强度与下楼梯膝关节屈曲力矩(KFM)脉冲呈中度正相关(r = 0.498, p < 0.05),而在术后1年未观察到这种正相关。在爬楼梯过程中,MR组1年时膝关节伸肌强度与KFM第一次峰值呈显著正相关(r = 0.606, p < 0.05)。结论:本探索性研究证实了后稳定TKA后股四头肌力量与膝关节矢状面生物力学之间的设计依赖性关联。虽然在临床或绝对生物力学结果方面没有观察到组间的显著差异,但在MR组中发现了任务和时间依赖的力量-生物力学关联,而在SR组中没有观察到这种关联,这表明在股四头肌延迟恢复患者中存在潜在的临床相关性。
{"title":"Design-dependent associations between quadriceps strength and sagittal knee biomechanics after posterior-stabilized total knee arthroplasty: A 3D motion analysis study","authors":"Ryota Fujii , Hyunho Lee , Christopher Stickley , Kazuyoshi Nakanishi","doi":"10.1016/j.jor.2026.01.005","DOIUrl":"10.1016/j.jor.2026.01.005","url":null,"abstract":"<div><h3>Purpose</h3><div>Single-radius (SR) and multi-radius (MR) femoral components are widely used in posterior-stabilized total knee arthroplasty (TKA). While previous studies have compared these designs primarily using clinical outcomes or basic kinematics, the relationship between quadriceps strength and dynamic sagittal-plane knee biomechanics remains insufficiently understood.</div></div><div><h3>Methods</h3><div>This prospective exploratory cohort study included 31 posterior-stabilized TKAs (SR: 16 knees; MR: 15 knees). Patients were evaluated at 6 months and 1 year postoperatively. Knee extension strength was measured using a handheld dynamometer. Sagittal-plane biomechanics during level walking, stair ascent, and stair descent were assessed using three-dimensional motion capture. External knee flexion moment (KFM) and KFM impulse were calculated. Associations between quadriceps strength and sagittal-plane biomechanical variables were analyzed using Spearman correlation coefficients.</div></div><div><h3>Results</h3><div>No significant between-group differences were observed in demographics or clinical activity levels. In the SR group, no significant associations were identified between quadriceps strength and sagittal-plane biomechanical variables at any postoperative time point. In contrast, the MR group demonstrated a moderate positive correlation between knee extensor strength and stair-descent knee flexion moment (KFM) impulse at 6 months postoperatively (r = 0.498, p < 0.05), which was not observed at 1 year postoperatively. During stair ascent, a significant positive correlation between knee extensor strength and the first peak KFM was observed in the MR group at 1 year (r = 0.606, p < 0.05).</div></div><div><h3>Conclusions</h3><div>This exploratory study demonstrated design-dependent associations between quadriceps strength and sagittal-plane knee biomechanics after posterior-stabilized TKA. While no significant between-group differences were observed in clinical or absolute biomechanical outcomes, task- and time-dependent strength–biomechanics associations were identified in the MR group, whereas no such associations were observed in the SR group, suggesting potential clinical relevance in patients with delayed quadriceps recovery.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"74 ","pages":"Pages 179-185"},"PeriodicalIF":1.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145978365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-04-01Epub Date: 2026-01-21DOI: 10.1016/j.jor.2026.01.010
Brittany McPhee , Doriann M. Alcaide , Monica Guirgus , Brandon Richmond , Vahe Yacoubian , Joey P. Johnson , Rebecca Rajfer
Objective
To examine outcomes of femoral neck fractures (FNFs) in non-geriatric adults treated with the Femoral Neck System (FNS; DePuy Synthes, Warsaw, IN) compared to three other fixation techniques.
Methods
This was a retrospective study in two Level I Trauma Centers (2019–2024) in adults 18–50 years old with FNFs (AO/OTA 31) that underwent surgical fixation. Patients were classified by fixation method: femoral neck system (FNS), dynamic hip screw (DHS), cephalomedullary nail (CMN) device and cannulated screws (CS). Outcomes compared between groups included: rates of reoperation, union, hardware failure, avascular necrosis (AVN), conversion to total hip arthroplasty (THA), operative time, intraoperative radiation exposure, surgical site infection (SSI) and length of stay (LOS).
Results
A total of 95 patients were included (FNS n = 27; DHS n = 15; CMN n = 15; CS n = 38). The majority of the patients were male (64.2 %), with an average age of 32.5 years and follow up time of 363 days. While being used predominantly for displaced fractures (66.7 %, p = 0.001), the FNS had significantly lower rates of hardware failure (74.1 %; p = 0.046), AVN (0 %, p = 0.034) and THA conversion (0 %, p = 0.029). CS had the highest union rates (89.5 %; p = 0.046), lowest reoperation rates (13.2 %; p = 0.030) and were used primarily for non-displaced fractures (63.2 %, p = 0.001). There were no differences among groups in surgical time (p = 0.191), or LOS (p = 0.592). A sub-analysis comparing reoperation rates after closed reduction showed that successful closed reduction was associated with not requiring reoperation (40.5 % vs 14.3 %; p = 0.026).
Conclusion
Fixation of FNFs in young adults with the FNS has lower rates of AVN, hardware failure and THA conversion compared to other fixation methods. Fixation with screws has the highest union rate and lowest reoperation rate in this demographic. Fixation of FNFs with the FNS has similar if not better outcomes when compared to other fixation methods. However, surgical factors such as fracture displacement and closed reduction may have influenced outcomes and require further study.
{"title":"Femoral neck system: A comparable fixation technique for femoral neck fractures in young adults","authors":"Brittany McPhee , Doriann M. Alcaide , Monica Guirgus , Brandon Richmond , Vahe Yacoubian , Joey P. Johnson , Rebecca Rajfer","doi":"10.1016/j.jor.2026.01.010","DOIUrl":"10.1016/j.jor.2026.01.010","url":null,"abstract":"<div><h3>Objective</h3><div>To examine outcomes of femoral neck fractures (FNFs) in non-geriatric adults treated with the Femoral Neck System (FNS; DePuy Synthes, Warsaw, IN) compared to three other fixation techniques.</div></div><div><h3>Methods</h3><div>This was a retrospective study in two Level I Trauma Centers (2019–2024) in adults 18–50 years old with FNFs (AO/OTA 31) that underwent surgical fixation. Patients were classified by fixation method: femoral neck system (FNS), dynamic hip screw (DHS), cephalomedullary nail (CMN) device and cannulated screws (CS). Outcomes compared between groups included: rates of reoperation, union, hardware failure, avascular necrosis (AVN), conversion to total hip arthroplasty (THA), operative time, intraoperative radiation exposure, surgical site infection (SSI) and length of stay (LOS).</div></div><div><h3>Results</h3><div>A total of 95 patients were included (FNS n = 27; DHS n = 15; CMN n = 15; CS n = 38). The majority of the patients were male (64.2 %), with an average age of 32.5 years and follow up time of 363 days. While being used predominantly for displaced fractures (66.7 %, p = 0.001), the FNS had significantly lower rates of hardware failure (74.1 %; p = 0.046), AVN (0 %, p = 0.034) and THA conversion (0 %, p = 0.029). CS had the highest union rates (89.5 %; p = 0.046), lowest reoperation rates (13.2 %; p = 0.030) and were used primarily for non-displaced fractures (63.2 %, p = 0.001). There were no differences among groups in surgical time (p = 0.191), or LOS (p = 0.592). A sub-analysis comparing reoperation rates after closed reduction showed that successful closed reduction was associated with not requiring reoperation (40.5 % vs 14.3 %; p = 0.026).</div></div><div><h3>Conclusion</h3><div>Fixation of FNFs in young adults with the FNS has lower rates of AVN, hardware failure and THA conversion compared to other fixation methods. Fixation with screws has the highest union rate and lowest reoperation rate in this demographic. Fixation of FNFs with the FNS has similar if not better outcomes when compared to other fixation methods. However, surgical factors such as fracture displacement and closed reduction may have influenced outcomes and require further study.</div></div><div><h3>Level of evidence</h3><div>III</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"74 ","pages":"Pages 239-243"},"PeriodicalIF":1.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146023305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-04-01Epub Date: 2025-12-25DOI: 10.1016/j.jor.2025.12.062
Chun Ru Lin , You-Rui Lin , Yi-Chen Liu , Eric H. Tischler , Ming-Hao Chen , Hao-Che Tang , Chien-Hao Chen , Chun-Yi Su , Yi-Sheng Chan , Sung Huang Laurent Tsai
Background
Inadequate treatment of posterior tibial plateau fractures can cause instability, yet no agreement exists regarding the optimal surgical approach for achieving favorable outcomes. Hence, the aim of this study is to assess and compare the postoperative outcomes of different posterior surgical techniques, including reverse L-shape, S-shaped, posterior medial, extended posterolateral, and posterolateral prone approaches.
Methods
To evaluate the efficacy of surgical approaches, we searched databases such as PubMed, Embase, Web of Science, The Cochrane Library, and Scopus. Studies published before October 26th, 2022 were included, and we followed the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. The study's outcomes comprised complications, infections, range of motion (ROM), operation time, and functional scores, and p-values <0.05 were considered significant. To conduct the meta-analysis, we utilized the R software.
Results
We included 8 studies with 104 patients. The extended posterolateral approach reduced incidence of complications and improved ROM, while the posterolateral prone approach reduced ROM. Conversely, the S-shaped approach was linked to lower HSS scores. No significant differences were found in infection rates or operative time among the various surgical approaches.
Conclusions
The extended posterolateral approach was associated with a lower incidence of complications and greater ROM compared to other surgical approaches. In contrast, the S-shaped approach was linked to lower HSS scores, and the posterolateral prone approach was associated with reduced ROM. These findings suggest that further prospective studies are necessary to establish the optimal surgical approach for posterior tibial plateau fractures.
背景:胫骨后平台骨折的治疗不充分会导致不稳定,但对于获得良好结果的最佳手术方法尚无一致意见。因此,本研究的目的是评估和比较不同后路手术技术的术后结果,包括反l型入路、s型入路、后内侧入路、扩展后外侧入路和后外侧俯卧入路。方法为了评估手术入路的疗效,我们检索PubMed、Embase、Web of Science、the Cochrane Library、Scopus等数据库。纳入了2022年10月26日之前发表的研究,我们遵循了系统评价和荟萃分析(PRISMA)指南的首选报告项目。研究结果包括并发症、感染、活动范围(ROM)、手术时间和功能评分,p值<;0.05认为显著。为了进行meta分析,我们使用R软件。结果纳入8项研究,共104例患者。延长后外侧入路可减少并发症发生率并改善ROM,而后外侧俯卧入路可减少ROM。相反,s形入路与较低的HSS评分有关。不同手术入路的感染率和手术时间无显著差异。结论与其他手术入路相比,扩展后外侧入路并发症发生率较低,ROM较大。相反,s形入路与HSS评分较低有关,后外侧俯位入路与ROM降低有关。这些发现表明,需要进一步的前瞻性研究来确定胫骨后平台骨折的最佳手术入路。
{"title":"Comparative analysis of different incision ways of posterior approach for posterior tibial plateau fractures: a systemic review and meta-analysis","authors":"Chun Ru Lin , You-Rui Lin , Yi-Chen Liu , Eric H. Tischler , Ming-Hao Chen , Hao-Che Tang , Chien-Hao Chen , Chun-Yi Su , Yi-Sheng Chan , Sung Huang Laurent Tsai","doi":"10.1016/j.jor.2025.12.062","DOIUrl":"10.1016/j.jor.2025.12.062","url":null,"abstract":"<div><h3>Background</h3><div>Inadequate treatment of posterior tibial plateau fractures can cause instability, yet no agreement exists regarding the optimal surgical approach for achieving favorable outcomes. Hence, the aim of this study is to assess and compare the postoperative outcomes of different posterior surgical techniques, including reverse L-shape, S-shaped, posterior medial, extended posterolateral, and posterolateral prone approaches.</div></div><div><h3>Methods</h3><div>To evaluate the efficacy of surgical approaches, we searched databases such as PubMed, Embase, Web of Science, The Cochrane Library, and Scopus. Studies published before October 26th, 2022 were included, and we followed the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. The study's outcomes comprised complications, infections, range of motion (ROM), operation time, and functional scores, and p-values <0.05 were considered significant. To conduct the meta-analysis, we utilized the R software.</div></div><div><h3>Results</h3><div>We included 8 studies with 104 patients. The extended posterolateral approach reduced incidence of complications and improved ROM, while the posterolateral prone approach reduced ROM. Conversely, the S-shaped approach was linked to lower HSS scores. No significant differences were found in infection rates or operative time among the various surgical approaches.</div></div><div><h3>Conclusions</h3><div>The extended posterolateral approach was associated with a lower incidence of complications and greater ROM compared to other surgical approaches. In contrast, the S-shaped approach was linked to lower HSS scores, and the posterolateral prone approach was associated with reduced ROM. These findings suggest that further prospective studies are necessary to establish the optimal surgical approach for posterior tibial plateau fractures.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"74 ","pages":"Pages 91-98"},"PeriodicalIF":1.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145882596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-04-01Epub Date: 2025-12-31DOI: 10.1016/j.jor.2025.12.069
Yanping Liu, Xijie Yu
Despite extensive research on osteoporosis therapies, systematic analysis of knowledge evolution and translational bottlenecks remains unexplored. This study presents the multidimensional bibliometric analysis of 10,247 publications (2015–2024) to decode paradigm shifts in osteoporosis therapeutics. Using CiteSpace and VOSviewer for bibliometric and visualization analyses, we observed a notable increase in annual publications, peaking in 2022. China and the United States led in research output, while European countries demonstrated higher citation impact. Shanghai Jiao Tong University, Harvard Medical School, and Chinese Academy of Sciences were the top three contributing institutions. Cooper, Cyrus is the most influential author. In academic publishing, Osteoporosis International has been identified as the journal with the most research results in the field of osteoporosis treatment. Keyword emergence analysis revealed a transition in research focus from randomized controlled trial and ovariectomized rats to drug, discontinuation, osteogenesis, bisphosphonate related osteonecrosis, network pharmacology, molecular docking, reduction, fixation, damage, American association, osteoporotic fracture, gut microbiota in the last five years, and that this is being explored in detail for future work. In summary, this study offers a thorough bibliometric analysis of osteoporosis therapeutics worldwide, providing scholars conducting analogous research in this field with valuable insights.
{"title":"A decade of progress and paradigm shifts in osteoporosis therapeutics: A bibliometric analysis","authors":"Yanping Liu, Xijie Yu","doi":"10.1016/j.jor.2025.12.069","DOIUrl":"10.1016/j.jor.2025.12.069","url":null,"abstract":"<div><div>Despite extensive research on osteoporosis therapies, systematic analysis of knowledge evolution and translational bottlenecks remains unexplored. This study presents the multidimensional bibliometric analysis of 10,247 publications (2015–2024) to decode paradigm shifts in osteoporosis therapeutics. Using CiteSpace and VOSviewer for bibliometric and visualization analyses, we observed a notable increase in annual publications, peaking in 2022. China and the United States led in research output, while European countries demonstrated higher citation impact. Shanghai Jiao Tong University, Harvard Medical School, and Chinese Academy of Sciences were the top three contributing institutions. Cooper, Cyrus is the most influential author. In academic publishing, <em>Osteoporosis International</em> has been identified as the journal with the most research results in the field of osteoporosis treatment. Keyword emergence analysis revealed a transition in research focus from randomized controlled trial and ovariectomized rats to drug, discontinuation, osteogenesis, bisphosphonate related osteonecrosis, network pharmacology, molecular docking, reduction, fixation, damage, American association, osteoporotic fracture, gut microbiota in the last five years, and that this is being explored in detail for future work. In summary, this study offers a thorough bibliometric analysis of osteoporosis therapeutics worldwide, providing scholars conducting analogous research in this field with valuable insights.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"74 ","pages":"Pages 104-112"},"PeriodicalIF":1.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145882593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-04-01Epub Date: 2025-12-29DOI: 10.1016/j.jor.2025.12.061
Dev Dayal , Maxwell Harrell , Clay Rahaman , Caleb Berta , Joe Dekle , Jeffrey C. Krout , Eugene Brabston , Walter Smith , Thomas E. Evely , Amit Momaya , Aaron J. Casp
Introduction
Hip arthroscopy (HA) is increasingly used to treat femoroacetabular impingement (FAI) and labral tears, with growing interest in the role of socioeconomic factors on postoperative outcomes. Prior literature suggests socioeconomic deprivation may worsen patient-reported outcomes (PROMs), but findings regarding the Area Deprivation Index (ADI) and urbanization status remain inconsistent. This study aimed to evaluate the difference in PROMs after HA secondary to symptomatic FAI and hip labral tears based on the residential urbanization status, demographic variables, and Area Deprivation Index (ADI) values of patients in our single-center cohort
Methods
A single-institution retrospective review was conducted on 86 patients who underwent HA between 2014 and 2023. Patients were categorized as urban or rural based on U.S. Census data and assigned national/state ADI scores based on their residential addresses. PROMs (mHHS, HOS-ADL, HOS-Sport, NAHS) were collected via telephone survey at ≥1 year postoperatively. Statistical comparisons and multivariable regression analyses were used to assess the impact of demographic variables and ADI on PROMs.
Results
There were no significant differences in PROMs between urban and rural patients. However, regression analysis revealed that national ADI and age were significantly negatively correlated with all PROMs (p < 0.05). Older age and higher ADI independently predicted worse postoperative outcomes. Interaction effects, such as age × BMI or age × ADI, also negatively influenced certain PROMs. Race and surgical indication showed limited interaction effects.
Conclusion
While urbanization status did not impact outcomes, higher socioeconomic deprivation (as measured by national ADI) and increased age were associated with significantly worse PROMs after HA at 1-year follow-up. These findings suggest that neighborhood-level socioeconomic disadvantage plays a more critical role than urban-rural classification in influencing recovery. Strategies aimed at addressing social determinants of health may improve HA outcomes, particularly in socioeconomically disadvantaged populations.
{"title":"Impact of demographic and socioeconomic factors and urbanization status on postoperative outcomes following hip arthroscopy","authors":"Dev Dayal , Maxwell Harrell , Clay Rahaman , Caleb Berta , Joe Dekle , Jeffrey C. Krout , Eugene Brabston , Walter Smith , Thomas E. Evely , Amit Momaya , Aaron J. Casp","doi":"10.1016/j.jor.2025.12.061","DOIUrl":"10.1016/j.jor.2025.12.061","url":null,"abstract":"<div><h3>Introduction</h3><div>Hip arthroscopy (HA) is increasingly used to treat femoroacetabular impingement (FAI) and labral tears, with growing interest in the role of socioeconomic factors on postoperative outcomes. Prior literature suggests socioeconomic deprivation may worsen patient-reported outcomes (PROMs), but findings regarding the Area Deprivation Index (ADI) and urbanization status remain inconsistent. This study aimed to evaluate the difference in PROMs after HA secondary to symptomatic FAI and hip labral tears based on the residential urbanization status, demographic variables, and Area Deprivation Index (ADI) values of patients in our single-center cohort</div></div><div><h3>Methods</h3><div>A single-institution retrospective review was conducted on 86 patients who underwent HA between 2014 and 2023. Patients were categorized as urban or rural based on U.S. Census data and assigned national/state ADI scores based on their residential addresses. PROMs (mHHS, HOS-ADL, HOS-Sport, NAHS) were collected via telephone survey at ≥1 year postoperatively. Statistical comparisons and multivariable regression analyses were used to assess the impact of demographic variables and ADI on PROMs.</div></div><div><h3>Results</h3><div>There were no significant differences in PROMs between urban and rural patients. However, regression analysis revealed that national ADI and age were significantly negatively correlated with all PROMs (p < 0.05). Older age and higher ADI independently predicted worse postoperative outcomes. Interaction effects, such as age × BMI or age × ADI, also negatively influenced certain PROMs. Race and surgical indication showed limited interaction effects.</div></div><div><h3>Conclusion</h3><div>While urbanization status did not impact outcomes, higher socioeconomic deprivation (as measured by national ADI) and increased age were associated with significantly worse PROMs after HA at 1-year follow-up. These findings suggest that neighborhood-level socioeconomic disadvantage plays a more critical role than urban-rural classification in influencing recovery. Strategies aimed at addressing social determinants of health may improve HA outcomes, particularly in socioeconomically disadvantaged populations.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"74 ","pages":"Pages 99-103"},"PeriodicalIF":1.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145882552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-04-01Epub Date: 2025-12-24DOI: 10.1016/j.jor.2025.12.057
Alexander Tham , Ragul Rajivan , Jared Rubin , James J. Butler , Mark Pianka , Akshay Nair , Hillary Campbell , Nicole Rynecki , Mackenzie Roof , John G. Kennedy
Background
Peroneal tendon disorders span tendinopathy, tenosynovitis, intrasheath subluxation, stenosis, and tears, and may be challenging to diagnose accurately with clinical examination and MRI alone. Peroneal tendoscopy offers a minimally invasive, diagnostic–therapeutic option. We systematically reviewed clinical indications, intraoperative findings, procedures, imaging accuracy, complications, and patient-reported outcomes following peroneal tendoscopy.
Methods
Eight studies (190 patients; 195 ankles) were reviewed. Data on demographics, indications, procedures, PROMs, return to sport (RTS), complications/failures, and imaging–tendoscopy agreement were extracted and pooled when constructs aligned. Random-effects meta-analyses generated pooled means or proportions with 95 % CIs (Hartung–Knapp adjustment). Where applicable, diagnostic performance of preoperative assessment was compared with tendoscopy as reference.
Results
Across 190 patients (195 ankles), pooled mean age was 32 years (95 % CI 25.0–39.0), follow-up 30.3 months (95 % CI 20.8–39.8); 71 % of ankles had traumatic aetiologies. Indications were broad, with recurrent subluxation/dislocation, intrasheath subluxation, and refractory lateral ankle pain common. Frequently performed procedures included synovectomy/debridement (94 ankles), groove deepening (34 ankles), excision of space occupying lesions (65 ankles; predominantly low-lying muscle bellies [LLMB] and peroneus quartus), tendon repair/tubularization (23 ankles), and tendoscopic retinacular repair (14 ankles). Six studies reported validated PROMS with four reporting AOFAS suitable for pooling. Postoperative AOFAS averaged 96.6 (95 % CI 94.3–99.0) with a pooled mean gain of +19.8 (95 % CI 18.5–21.2); JSSF, FAOS and SF-12 improved significantly. RTS occurred at a pooled 13.3 weeks (95 % CI 10.6–16.0), with RTS of 12.2 ± 0.6 weeks after tendoscopic retinacular stabilization and 14.8 ± 2.0 weeks after groove deepening. Overall complications were 7.6 % (13 events) and mainly consisted of persistent ankle pain and minor wound issues. Failure rate was 1.5 % and two revision surgeries (1.0 %) were reported. Diagnostic agreement was high at the aggregate level (MRI overall sensitivity 0.90, specificity 0.72), but lesion-level performance varied: MRI was strong for tears and tenosynovitis, weaker for stenosis. Composite preoperative diagnosis in a large series showed high specificity (0.97) but only moderate sensitivity (0.76), with LLMB frequently under-recognized preoperatively.
Conclusions
Peroneal tendoscopy provides meaningful functional gains, timely RTS, and a low adverse-event burden across a wide indication spectrum, and it complements imaging by clarifying dynamic/space-conflict pathology. Longer, prospective comparative studies are warranted.
腓肌腱疾病包括肌腱病、腱鞘炎、腱鞘内半脱位、狭窄和撕裂,仅凭临床检查和MRI可能难以准确诊断。腓肌腱镜检查提供了一种微创、诊断治疗的选择。我们系统地回顾了腓肌腱镜检查后的临床适应症、术中发现、手术、成像准确性、并发症和患者报告的结果。方法回顾性分析8项研究(190例患者,195例踝关节)。当结构对齐时,提取和汇总有关人口统计学、适应症、手术、prom、恢复运动(RTS)、并发症/失败和成像-肌腱镜检查一致性的数据。随机效应荟萃分析产生95% ci的汇总平均值或比例(Hartung-Knapp校正)。在适用的情况下,将术前评估的诊断效果与肌腱镜检查进行比较作为参考。结果190例患者(195踝关节),合并平均年龄32岁(95% CI 25.0 ~ 39.0),随访30.3个月(95% CI 20.8 ~ 39.8);71%的踝关节有外伤性病因。适应症广泛,复发性半脱位/脱位,鞘内半脱位,常见的难治性踝关节外侧疼痛。常用的手术包括滑膜切除术/清创(94个踝关节),沟加深(34个踝关节),占位性病变切除(65个踝关节,主要是低处肌肉腹部[LLMB]和腓骨四角肌),肌腱修复/管化(23个踝关节),肌腱镜下支持带修复(14个踝关节)。6项研究报告了验证的PROMS,其中4项报告了适合合并的AOFAS。术后AOFAS平均为96.6 (95% CI 94.3-99.0),合并平均增益为+19.8 (95% CI 18.5-21.2);JSSF、FAOS和SF-12显著改善。RTS发生在13.3周(95% CI 10.6-16.0),其中肌腱镜下支持带稳定后的RTS为12.2±0.6周,沟加深后的RTS为14.8±2.0周。总并发症为7.6%(13次),主要包括持续的踝关节疼痛和轻微的伤口问题。失败率为1.5%,2例翻修手术(1.0%)。总体水平的诊断一致性很高(MRI总敏感性0.90,特异性0.72),但病变水平表现不同:MRI对撕裂和腱鞘炎的诊断较强,对狭窄的诊断较弱。术前综合诊断在大序列中显示出高特异性(0.97),但只有中等敏感性(0.76),LLMB在术前经常被低估。结论肌腱镜检查在广泛的适应症范围内提供了有意义的功能获益,及时的RTS和低不良事件负担,并通过澄清动态/空间冲突病理补充了影像学。更长的前瞻性比较研究是有必要的。
{"title":"Peroneal tendoscopy for peroneal tendon disorders: A systematic review of indications, diagnostic utility, and clinical outcomes","authors":"Alexander Tham , Ragul Rajivan , Jared Rubin , James J. Butler , Mark Pianka , Akshay Nair , Hillary Campbell , Nicole Rynecki , Mackenzie Roof , John G. Kennedy","doi":"10.1016/j.jor.2025.12.057","DOIUrl":"10.1016/j.jor.2025.12.057","url":null,"abstract":"<div><h3>Background</h3><div>Peroneal tendon disorders span tendinopathy, tenosynovitis, intrasheath subluxation, stenosis, and tears, and may be challenging to diagnose accurately with clinical examination and MRI alone. Peroneal tendoscopy offers a minimally invasive, diagnostic–therapeutic option. We systematically reviewed clinical indications, intraoperative findings, procedures, imaging accuracy, complications, and patient-reported outcomes following peroneal tendoscopy.</div></div><div><h3>Methods</h3><div>Eight studies (190 patients; 195 ankles) were reviewed. Data on demographics, indications, procedures, PROMs, return to sport (RTS), complications/failures, and imaging–tendoscopy agreement were extracted and pooled when constructs aligned. Random-effects meta-analyses generated pooled means or proportions with 95 % CIs (Hartung–Knapp adjustment). Where applicable, diagnostic performance of preoperative assessment was compared with tendoscopy as reference.</div></div><div><h3>Results</h3><div>Across 190 patients (195 ankles), pooled mean age was 32 years (95 % CI 25.0–39.0), follow-up 30.3 months (95 % CI 20.8–39.8); 71 % of ankles had traumatic aetiologies. Indications were broad, with recurrent subluxation/dislocation, intrasheath subluxation, and refractory lateral ankle pain common. Frequently performed procedures included synovectomy/debridement (94 ankles), groove deepening (34 ankles), excision of space occupying lesions (65 ankles; predominantly low-lying muscle bellies [LLMB] and peroneus quartus), tendon repair/tubularization (23 ankles), and tendoscopic retinacular repair (14 ankles). Six studies reported validated PROMS with four reporting AOFAS suitable for pooling. Postoperative AOFAS averaged 96.6 (95 % CI 94.3–99.0) with a pooled mean gain of +19.8 (95 % CI 18.5–21.2); JSSF, FAOS and SF-12 improved significantly. RTS occurred at a pooled 13.3 weeks (95 % CI 10.6–16.0), with RTS of 12.2 ± 0.6 weeks after tendoscopic retinacular stabilization and 14.8 ± 2.0 weeks after groove deepening. Overall complications were 7.6 % (13 events) and mainly consisted of persistent ankle pain and minor wound issues. Failure rate was 1.5 % and two revision surgeries (1.0 %) were reported. Diagnostic agreement was high at the aggregate level (MRI overall sensitivity 0.90, specificity 0.72), but lesion-level performance varied: MRI was strong for tears and tenosynovitis, weaker for stenosis. Composite preoperative diagnosis in a large series showed high specificity (0.97) but only moderate sensitivity (0.76), with LLMB frequently under-recognized preoperatively.</div></div><div><h3>Conclusions</h3><div>Peroneal tendoscopy provides meaningful functional gains, timely RTS, and a low adverse-event burden across a wide indication spectrum, and it complements imaging by clarifying dynamic/space-conflict pathology. Longer, prospective comparative studies are warranted.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"74 ","pages":"Pages 24-32"},"PeriodicalIF":1.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145839356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hip abductor weakness is common after proximal femoral fracture and may contribute to gait instability. The influence of postoperative hip alignment on early recovery of hip abductor strength during inpatient rehabilitation after surgery remains unclear.
Objective
To examine longitudinal changes in hip abductor strength and identify factors associated with the operated-to-non-operated hip abductor strength ratio at discharge, focusing on surgical procedure and radiographic alignment.
Methods
This retrospective observational cohort study enrolled 64 patients transferred to a rehabilitation hospital after proximal femoral fracture surgery (34 femoral neck fractures treated with hemiarthroplasty; 30 intertrochanteric fractures treated with cephalomedullary nailing). Hip abductor strength was measured using a handheld dynamometer at rehabilitation admission and discharge and normalized by body weight. Radiographic parameters were measured on supine anteroposterior pelvic radiographs; side-to-side differences (operated minus non-operated) were calculated for the neck–shaft angle, hip center of rotation, femoral offset, and trochanteric height. Multivariable linear regression (ANCOVA-type) was performed with the discharge strength ratio as the dependent variable and the admission strength ratio as an adjustment factor.
Results
Hip abductor strength improved on both sides (p < 0.001). The operated side increased from 1.04 ± 0.5 to 1.8 ± 0.7 N/kg and the non-operated side from 1.6 ± 0.6 to 2.3 ± 0.8 N/kg; the operated-to-non-operated ratio improved from 62.7 % to 72.9 %. In the adjusted model (R2 = 0.325), cephalomedullary nailing (vs hemiarthroplasty) was associated with a higher discharge strength ratio (B = 0.114, p = 0.027). A greater neck–shaft angle difference was also associated with a higher discharge strength ratio (B = 0.0073 per degree, p = 0.011). The admission strength ratio remained a significant predictor (B = 0.245, p = 0.002).
Conclusions
Early recovery of the hip abductor strength ratio after proximal femoral fracture was associated with surgical procedure and postoperative neck–shaft angle asymmetry, independent of baseline strength ratio. Postoperative radiographic alignment may aid in stratifying recovery and tailoring rehabilitation, although causal inference is limited.
{"title":"Association of surgical procedure and radiographic hip alignment with hip abductor strength ratio at discharge after proximal femoral fracture surgery","authors":"Satoshi Hakukawa, Shunsuke Onuma, Kanata Yoshihara","doi":"10.1016/j.jor.2025.12.068","DOIUrl":"10.1016/j.jor.2025.12.068","url":null,"abstract":"<div><h3>Background</h3><div>Hip abductor weakness is common after proximal femoral fracture and may contribute to gait instability. The influence of postoperative hip alignment on early recovery of hip abductor strength during inpatient rehabilitation after surgery remains unclear.</div></div><div><h3>Objective</h3><div>To examine longitudinal changes in hip abductor strength and identify factors associated with the operated-to-non-operated hip abductor strength ratio at discharge, focusing on surgical procedure and radiographic alignment.</div></div><div><h3>Methods</h3><div>This retrospective observational cohort study enrolled 64 patients transferred to a rehabilitation hospital after proximal femoral fracture surgery (34 femoral neck fractures treated with hemiarthroplasty; 30 intertrochanteric fractures treated with cephalomedullary nailing). Hip abductor strength was measured using a handheld dynamometer at rehabilitation admission and discharge and normalized by body weight. Radiographic parameters were measured on supine anteroposterior pelvic radiographs; side-to-side differences (operated minus non-operated) were calculated for the neck–shaft angle, hip center of rotation, femoral offset, and trochanteric height. Multivariable linear regression (ANCOVA-type) was performed with the discharge strength ratio as the dependent variable and the admission strength ratio as an adjustment factor.</div></div><div><h3>Results</h3><div>Hip abductor strength improved on both sides (p < 0.001). The operated side increased from 1.04 ± 0.5 to 1.8 ± 0.7 N/kg and the non-operated side from 1.6 ± 0.6 to 2.3 ± 0.8 N/kg; the operated-to-non-operated ratio improved from 62.7 % to 72.9 %. In the adjusted model (R<sup>2</sup> = 0.325), cephalomedullary nailing (vs hemiarthroplasty) was associated with a higher discharge strength ratio (B = 0.114, p = 0.027). A greater neck–shaft angle difference was also associated with a higher discharge strength ratio (B = 0.0073 per degree, p = 0.011). The admission strength ratio remained a significant predictor (B = 0.245, p = 0.002).</div></div><div><h3>Conclusions</h3><div>Early recovery of the hip abductor strength ratio after proximal femoral fracture was associated with surgical procedure and postoperative neck–shaft angle asymmetry, independent of baseline strength ratio. Postoperative radiographic alignment may aid in stratifying recovery and tailoring rehabilitation, although causal inference is limited.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"74 ","pages":"Pages 131-137"},"PeriodicalIF":1.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145927816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-04-01Epub Date: 2026-01-08DOI: 10.1016/j.jor.2026.01.007
Sean Bae , Mark Ehioghae , Jonathan P. Japa , Ala Alshomali , Aaron Phung , Linus Lee , Justin Hyde , Jamie Lee , Kevin Yoon , Addisu Mesfin
Background
Sacral chordomas are rare malignant tumors arising from notochordal remnants that can be identified incidentally or present with sacral pain. Although surgical resection is the accepted standard treatment, some patients forgo surgery due to associated morbidity and complications. Nonoperative alternatives, including radiotherapies, have emerged, but literature on their outcomes remains scarce. The purpose of this study was to evaluate the outcomes of nonoperative management of sacral chordomas.
Methods
We conducted a systematic review of the literature utilizing PubMed. Search keywords included “nonoperative treatment,” “sacral chordomas,” “radiotherapy,” and “functional outcomes.” Studies involving sacral chordoma patients who underwent nonoperative treatment were included; patients with surgical treatment and hybrid therapies that included surgery were excluded from the analysis.
Results
Eleven clinical studies on nonoperative management of sacral chordomas with 52 patients aged between 35 and 85 years (mean = 62.8) were identified. Males were affected at higher rates than females (73.1 % vs 26.9 %). S1 (15.4 %) and S2 (25 %) were the most affected spinal segments. CT-guided biopsy was the most common method of tumor diagnosis (82.7 %). Carbon ion radiotherapy (CIRT) and proton beam therapy were the most common treatment methods, with 57.7 % of patients reporting recurrence-free survival at a mean follow-up of 24 months.
Conclusion
Nonoperative management of sacral chordomas shows promising outcomes for patients who are not candidates for surgery. Although recurrence remains a risk, nonoperative management may offer meaningful functional preservation and local disease control.
背景:骶脊索瘤是一种罕见的恶性肿瘤,起源于脊索残余,可偶然发现或伴有骶痛。虽然手术切除是公认的标准治疗方法,但由于相关的发病率和并发症,一些患者放弃手术。包括放射治疗在内的非手术替代疗法已经出现,但关于其结果的文献仍然很少。本研究的目的是评估非手术治疗骶脊索瘤的结果。方法利用PubMed对相关文献进行系统综述。搜索关键词包括“非手术治疗”、“骶脊索瘤”、“放疗”和“功能结果”。包括接受非手术治疗的骶脊索瘤患者的研究;手术治疗和混合治疗包括手术的患者被排除在分析之外。结果对52例35 ~ 85岁的骶脊索瘤患者进行非手术治疗的临床研究,平均62.8岁。男性受影响的比例高于女性(73.1% vs 26.9%)。S1(15.4%)和S2(25%)是受影响最大的脊柱节段。ct引导下活检是最常见的肿瘤诊断方法(82.7%)。碳离子放射治疗(CIRT)和质子束治疗是最常见的治疗方法,平均随访24个月,57.7%的患者报告无复发生存。结论非手术治疗骶脊索瘤对不需要手术治疗的患者有较好的疗效。虽然复发仍有风险,但非手术治疗可能提供有意义的功能保留和局部疾病控制。
{"title":"Nonoperative management of sacral chordomas: A systematic review of the literature","authors":"Sean Bae , Mark Ehioghae , Jonathan P. Japa , Ala Alshomali , Aaron Phung , Linus Lee , Justin Hyde , Jamie Lee , Kevin Yoon , Addisu Mesfin","doi":"10.1016/j.jor.2026.01.007","DOIUrl":"10.1016/j.jor.2026.01.007","url":null,"abstract":"<div><h3>Background</h3><div>Sacral chordomas are rare malignant tumors arising from notochordal remnants that can be identified incidentally or present with sacral pain. Although surgical resection is the accepted standard treatment, some patients forgo surgery due to associated morbidity and complications. Nonoperative alternatives, including radiotherapies, have emerged, but literature on their outcomes remains scarce. The purpose of this study was to evaluate the outcomes of nonoperative management of sacral chordomas.</div></div><div><h3>Methods</h3><div>We conducted a systematic review of the literature utilizing PubMed. Search keywords included “nonoperative treatment,” “sacral chordomas,” “radiotherapy,” and “functional outcomes.” Studies involving sacral chordoma patients who underwent nonoperative treatment were included; patients with surgical treatment and hybrid therapies that included surgery were excluded from the analysis.</div></div><div><h3>Results</h3><div>Eleven clinical studies on nonoperative management of sacral chordomas with 52 patients aged between 35 and 85 years (mean = 62.8) were identified. Males were affected at higher rates than females (73.1 % vs 26.9 %). S1 (15.4 %) and S2 (25 %) were the most affected spinal segments. CT-guided biopsy was the most common method of tumor diagnosis (82.7 %). Carbon ion radiotherapy (CIRT) and proton beam therapy were the most common treatment methods, with 57.7 % of patients reporting recurrence-free survival at a mean follow-up of 24 months.</div></div><div><h3>Conclusion</h3><div>Nonoperative management of sacral chordomas shows promising outcomes for patients who are not candidates for surgery. Although recurrence remains a risk, nonoperative management may offer meaningful functional preservation and local disease control.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"74 ","pages":"Pages 186-194"},"PeriodicalIF":1.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145978892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-04-01Epub Date: 2026-02-02DOI: 10.1016/j.jor.2026.02.004
Fatih Emre Topsakal, Ekrem Özdemir, Nasuhi Altay
Background
The management of massive rotator cuff tears (MRCTs) without glenohumeral arthritis presents a significant clinical challenge. The choice between primary arthroscopic rotator cuff repair (RCR) and reverse shoulder arthroplasty (RSA) remains controversial, with limited comparative data on patient-centered outcomes.
Purpose
To compare functional outcomes, patient-priority outcome domains, and complication rates between primary arthroscopic RCR and primary RSA in patients with massive rotator cuff tears.
Methods
This retrospective cohort study included 70 patients (36 RCR, 34 RSA) treated between 2022-2024 with minimum 12-month follow-up (mean 24.3 ± 6.7 months). Patient demographics, preoperative imaging findings (Goutallier fatty infiltration, Patte retraction, Hamada staging), traditional functional scores (ASES, Constant, DASH, VAS), range of motion, and patient-priority outcome domains (pain-free sleep, overhead activity, internal rotation tasks, heavy work capacity, return to sports) were compared using appropriate statistical methods.
Results
RCR patients were significantly younger (64.8 ± 7.2 vs. 72.1 ± 6.9 years, p < 0.001) with lower Goutallier grades (Grade≥3: 44.7% vs. 94.4%, p < 0.001). Both groups achieved significant pain reduction and functional improvement. At final follow-up, RCR demonstrated superior active flexion (146.3° ± 24.8° vs. 117.2° ± 27.3°, p < 0.001), internal rotation (L3 vs. S1 level, p = 0.001), and ASES scores (79.2 ± 23.4 vs. 69.8 ± 26.1, p = 0.042). RCR showed significant advantages in patient-priority domains including overhead activity (3.2 ± 0.8 vs. 2.6 ± 0.9, p = 0.002), internal rotation tasks (3.3 ± 0.7 vs. 2.2 ± 1.0, p < 0.001), and return to sports (2.6 ± 1.1 vs. 1.8 ± 0.9, p = 0.001). Complication rates were similar (11.1% vs. 8.8%, p = 0.734).
Conclusion
In younger, active patients with adequate tissue quality, primary arthroscopic RCR provides superior range of motion and patient-centered functional outcomes. RSA remains a reliable option for elderly patients with advanced fatty infiltration and chronic pseudoparalysis. Careful evaluation of these factors is critical for optimal patient selection.
背景:无肩关节关节炎的大量肩袖撕裂(mrct)的处理是一个重大的临床挑战。初级关节镜下肩袖修复(RCR)和反向肩关节置换术(RSA)之间的选择仍然存在争议,以患者为中心的结果的比较数据有限。目的比较原发性关节镜下RCR和原发性RSA对大面积肩袖撕裂患者的功能结局、患者优先考虑的结果域和并发症发生率。方法回顾性队列研究纳入70例患者(RCR 36例,RSA 34例),随访时间为2022-2024年,随访时间最短12个月(平均24.3±6.7个月)。采用适当的统计方法比较患者人口统计学特征、术前影像学表现(Goutallier脂肪浸润、Patte回缩、Hamada分期)、传统功能评分(ASES、Constant、DASH、VAS)、运动范围和患者优先考虑的结果域(无痛睡眠、头顶活动、内部旋转任务、繁重工作能力、重返运动)。结果rcr患者明显年轻化(64.8±7.2岁比72.1±6.9岁,p < 0.001), Goutallier评分较低(≥3级:44.7%比94.4%,p < 0.001)。两组均获得显著的疼痛减轻和功能改善。在最后的随访中,RCR显示了更好的主动屈曲(146.3°±24.8°vs. 117.2°±27.3°,p < 0.001),内旋(L3 vs. S1水平,p = 0.001)和asas评分(79.2±23.4 vs. 69.8±26.1,p = 0.042)。RCR在患者优先领域显示出显著优势,包括头顶活动(3.2±0.8 vs. 2.6±0.9,p = 0.002)、内旋任务(3.3±0.7 vs. 2.2±1.0,p < 0.001)和重返运动(2.6±1.1 vs. 1.8±0.9,p = 0.001)。并发症发生率相似(11.1% vs 8.8%, p = 0.734)。结论在年轻、活跃、组织质量良好的患者中,初级关节镜下RCR提供了更好的活动范围和以患者为中心的功能结果。对于晚期脂肪浸润和慢性假性麻痹的老年患者,RSA仍然是一个可靠的选择。仔细评估这些因素对于最佳患者选择至关重要。
{"title":"Rotator cuff repair vs. reverse arthroplasty for massive tears: A patient-centered outcome analysis","authors":"Fatih Emre Topsakal, Ekrem Özdemir, Nasuhi Altay","doi":"10.1016/j.jor.2026.02.004","DOIUrl":"10.1016/j.jor.2026.02.004","url":null,"abstract":"<div><h3>Background</h3><div>The management of massive rotator cuff tears (MRCTs) without glenohumeral arthritis presents a significant clinical challenge. The choice between primary arthroscopic rotator cuff repair (RCR) and reverse shoulder arthroplasty (RSA) remains controversial, with limited comparative data on patient-centered outcomes.</div></div><div><h3>Purpose</h3><div>To compare functional outcomes, patient-priority outcome domains, and complication rates between primary arthroscopic RCR and primary RSA in patients with massive rotator cuff tears.</div></div><div><h3>Methods</h3><div>This retrospective cohort study included 70 patients (36 RCR, 34 RSA) treated between 2022-2024 with minimum 12-month follow-up (mean 24.3 ± 6.7 months). Patient demographics, preoperative imaging findings (Goutallier fatty infiltration, Patte retraction, Hamada staging), traditional functional scores (ASES, Constant, DASH, VAS), range of motion, and patient-priority outcome domains (pain-free sleep, overhead activity, internal rotation tasks, heavy work capacity, return to sports) were compared using appropriate statistical methods.</div></div><div><h3>Results</h3><div>RCR patients were significantly younger (64.8 ± 7.2 vs. 72.1 ± 6.9 years, p < 0.001) with lower Goutallier grades (Grade≥3: 44.7% vs. 94.4%, p < 0.001). Both groups achieved significant pain reduction and functional improvement. At final follow-up, RCR demonstrated superior active flexion (146.3° ± 24.8° vs. 117.2° ± 27.3°, p < 0.001), internal rotation (L3 vs. S1 level, p = 0.001), and ASES scores (79.2 ± 23.4 vs. 69.8 ± 26.1, p = 0.042). RCR showed significant advantages in patient-priority domains including overhead activity (3.2 ± 0.8 vs. 2.6 ± 0.9, p = 0.002), internal rotation tasks (3.3 ± 0.7 vs. 2.2 ± 1.0, p < 0.001), and return to sports (2.6 ± 1.1 vs. 1.8 ± 0.9, p = 0.001). Complication rates were similar (11.1% vs. 8.8%, p = 0.734).</div></div><div><h3>Conclusion</h3><div>In younger, active patients with adequate tissue quality, primary arthroscopic RCR provides superior range of motion and patient-centered functional outcomes. RSA remains a reliable option for elderly patients with advanced fatty infiltration and chronic pseudoparalysis. Careful evaluation of these factors is critical for optimal patient selection.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"74 ","pages":"Pages 314-322"},"PeriodicalIF":1.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146170268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}