首页 > 最新文献

Journal of Physiological Anthropology最新文献

英文 中文
Comparisons between wrinkles and photo-ageing detected and self-reported by the participant or identified by trained assessors reveal insights from Chinese individuals in the Singapore/Malaysia Cross-sectional Genetics Epidemiology Study (SMCGES) cohort 比较由参与者自我报告或由训练有素的评估人员识别的皱纹和光老化情况,揭示新加坡/马来西亚横断面遗传流行病学研究(SMCGES)队列中华人的见解
IF 3.1 4区 医学 Q1 Social Sciences Pub Date : 2024-05-18 DOI: 10.1186/s40101-024-00361-8
J. Y. Ng, Hongyu Zhou, Tianqi Li, F. Chew
{"title":"Comparisons between wrinkles and photo-ageing detected and self-reported by the participant or identified by trained assessors reveal insights from Chinese individuals in the Singapore/Malaysia Cross-sectional Genetics Epidemiology Study (SMCGES) cohort","authors":"J. Y. Ng, Hongyu Zhou, Tianqi Li, F. Chew","doi":"10.1186/s40101-024-00361-8","DOIUrl":"https://doi.org/10.1186/s40101-024-00361-8","url":null,"abstract":"","PeriodicalId":16768,"journal":{"name":"Journal of Physiological Anthropology","volume":"11 4","pages":"1-22"},"PeriodicalIF":3.1,"publicationDate":"2024-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140962064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Allostatic load and frailty do not covary significantly among older residents of Greater Poland 在大波兰地区的老年居民中,代谢负荷和虚弱程度的共线关系并不明显
IF 3.1 4区 医学 Q1 Social Sciences Pub Date : 2024-04-20 DOI: 10.1186/s40101-024-00359-2
Jan Jeszka, Darian Hummel, Malgorzata Woźniewicz, Tomoko Morinaka, Yoshiaki Sone, Douglas E. Crews
Physiological dysregulation/allostatic load and the geriatric syndrome frailty increase with age. As a neurophysiological response system, allostasis supports survival by limiting stressor-related damage. Frailty reflects decreased strength, endurance, and physical abilities secondary to losses of muscle and bone with age. One suggestion, based on large cohort studies of person’s ages 70 + years, is that frailty contributes to allostatic load at older ages. However, small community-based research has not confirmed this specific association. To further explore possible associations between allostatic load and frailty, we enrolled 211 residents of Greater Poland aged 55–91 years living in a small village (Nekla, N = 104) and an urban center and capital of Greater Poland (Poznan, N = 107). For each, we recorded age, self-reported sex, and residence and estimated a 10-biomarker allostatic load score (ALS) and an 8-biomarker frailty index. We anticipated the following: higher ALS and frailty among men and rural residents; for frailty but not ALS to be higher at older ages; significant associations of ALS with sex and place of residence, but not with age or frailty. The significance of observed associations was evaluated by t-tests and multivariate regression. ALS did not vary significantly between men and women nor between Nekla and Poznan residents overall. However, women showed significantly higher frailty than men. Nekla men showed significantly higher ALS but not frailty, while Nekla women showed nonsignificantly higher ALS and lower frailty than Poznan. In multivariate analyses, neither age, nor sex, nor residence was associated with ALS. Conversely, age, sex, and residence, but not ALS, are associated significantly with frailty. In Nekla, both age and sex, but in Poznan only age, are associated with ALS. Among women, both age and residence, but among men, neither associated with ALS. In no case did ALS associate significantly with frailty. In this sample, lifestyle factors associated with residence, age, and sex influence stress-related physiology, less so in women, while ALS and frailty do not covary, suggesting their underlying promoters are distinct. Similar complex associations of physiological dysregulation with frailty, age, sex, and residence likely exist within many local settings. Knowledge of this variation likely will aid in supporting health and healthcare services among seniors.
随着年龄的增长,生理失调/失衡负荷和老年虚弱综合症也会增加。作为一种神经生理反应系统,失衡通过限制与压力相关的损伤来支持生存。虚弱反映了随着年龄的增长,肌肉和骨骼的损失导致力量、耐力和体能的下降。根据对 70 岁以上人群进行的大型队列研究,有一种观点认为,年老体弱是造成异位负荷的原因之一。然而,基于社区的小型研究并未证实这种特定的关联。为了进一步探究各静态负荷与虚弱之间可能存在的关联,我们招募了 211 名年龄在 55-91 岁之间的大波兰地区居民,他们分别居住在一个小村庄(内克拉,104 人)和一个大波兰地区的城市中心和首府(波兹南,107 人)。我们记录了每个人的年龄、自我报告的性别和居住地,并估算了 10 个生物标志物的虚弱负荷评分 (ALS) 和 8 个生物标志物的虚弱指数。我们预计会出现以下情况:男性和农村居民的 ALS 和虚弱程度更高;年龄越大,虚弱程度越高,但 ALS 不高;ALS 与性别和居住地有显著关联,但与年龄或虚弱程度无关。通过 t 检验和多变量回归评估了观察到的关联的显著性。ALS在男性和女性之间以及在内克拉和波兹南居民之间没有明显差异。不过,女性的虚弱程度明显高于男性。与波兹南相比,内克拉男性的肌萎缩性脊髓侧索硬化症明显较高,但虚弱程度并不明显;而内克拉女性的肌萎缩性脊髓侧索硬化症并不明显较高,但虚弱程度较低。在多变量分析中,年龄、性别和居住地都与 ALS 无关。相反,年龄、性别和居住地(而非 ALS)与虚弱有显著关联。在内克拉,年龄和性别都与 ALS 有关,但在波兹南,只有年龄与 ALS 有关。在女性中,年龄和居住地都与 ALS 有关,但在男性中,年龄和居住地都与 ALS 无关。没有任何一种 ALS 与体弱有明显的关联。在这一样本中,与居住地、年龄和性别相关的生活方式因素会影响与压力相关的生理机能,但对女性的影响较小,而 ALS 与体弱并不相关,这表明它们的潜在启动因子是不同的。生理失调与体弱、年龄、性别和居住地之间可能存在类似的复杂关联。对这种变化的了解可能有助于为老年人的健康和医疗保健服务提供支持。
{"title":"Allostatic load and frailty do not covary significantly among older residents of Greater Poland","authors":"Jan Jeszka, Darian Hummel, Malgorzata Woźniewicz, Tomoko Morinaka, Yoshiaki Sone, Douglas E. Crews","doi":"10.1186/s40101-024-00359-2","DOIUrl":"https://doi.org/10.1186/s40101-024-00359-2","url":null,"abstract":"Physiological dysregulation/allostatic load and the geriatric syndrome frailty increase with age. As a neurophysiological response system, allostasis supports survival by limiting stressor-related damage. Frailty reflects decreased strength, endurance, and physical abilities secondary to losses of muscle and bone with age. One suggestion, based on large cohort studies of person’s ages 70 + years, is that frailty contributes to allostatic load at older ages. However, small community-based research has not confirmed this specific association. To further explore possible associations between allostatic load and frailty, we enrolled 211 residents of Greater Poland aged 55–91 years living in a small village (Nekla, N = 104) and an urban center and capital of Greater Poland (Poznan, N = 107). For each, we recorded age, self-reported sex, and residence and estimated a 10-biomarker allostatic load score (ALS) and an 8-biomarker frailty index. We anticipated the following: higher ALS and frailty among men and rural residents; for frailty but not ALS to be higher at older ages; significant associations of ALS with sex and place of residence, but not with age or frailty. The significance of observed associations was evaluated by t-tests and multivariate regression. ALS did not vary significantly between men and women nor between Nekla and Poznan residents overall. However, women showed significantly higher frailty than men. Nekla men showed significantly higher ALS but not frailty, while Nekla women showed nonsignificantly higher ALS and lower frailty than Poznan. In multivariate analyses, neither age, nor sex, nor residence was associated with ALS. Conversely, age, sex, and residence, but not ALS, are associated significantly with frailty. In Nekla, both age and sex, but in Poznan only age, are associated with ALS. Among women, both age and residence, but among men, neither associated with ALS. In no case did ALS associate significantly with frailty. In this sample, lifestyle factors associated with residence, age, and sex influence stress-related physiology, less so in women, while ALS and frailty do not covary, suggesting their underlying promoters are distinct. Similar complex associations of physiological dysregulation with frailty, age, sex, and residence likely exist within many local settings. Knowledge of this variation likely will aid in supporting health and healthcare services among seniors.","PeriodicalId":16768,"journal":{"name":"Journal of Physiological Anthropology","volume":"26 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140627673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Triglyceride-glucose index is capable of identifying metabolically obese, normal-weight older individuals 甘油三酯-葡萄糖指数能够识别代谢肥胖、体重正常的老年人
IF 3.1 4区 医学 Q1 Social Sciences Pub Date : 2024-02-03 DOI: 10.1186/s40101-024-00355-6
Bokun Kim, Keisuke Taniguchi, Tomonori Isobe, Sechang Oh
The concept of metabolically obese, normal weight (MONW) has emerged to describe individuals with a normal body mass index (BMI) who are at a relatively high risk of chronic diseases. However, BMI itself is a suboptimal index for the assessment of the health risks associated with visceral fat. The triglyceride-glucose (TyG) index is considered to be a reliable and cost-effective marker of insulin resistance. Therefore, in the present study, we aimed to determine the TyG index cut-off values that could be used to define MONW in older people and to determine the usefulness of these values for the prediction of chronic diseases. A total of 4,721 participants in the Korea National Health and Nutritional Examination Survey who were ≥ 60 years of age and did not have underweight or obesity were included. MONW was defined using the criteria for metabolic syndrome (MS), and the TyG index was calculated on the basis of the fasting plasma triglyceride and glucose concentrations. Chronic diseases, including T2DM, hypertension, and non-alcoholic fatty liver disease (NAFLD), were diagnosed. The prevalence of MS increased from the lowest to the highest TyG index tertile. The cut-off values of the TyG index for MONW were calculated as 8.88 and 8.80 for males and females, respectively. MONW, defined using these cut-off values, was associated with high odds ratios for NAFLD, T2DM, and hypertension in both males and females. The TyG index cut-off values calculated in the present study can be used to discriminate individuals with MONW from other older individuals without obesity and to predict the risk of chronic diseases. These findings show that the TyG index is an effective and cost-efficient method of assessing the risk of chronic diseases in people with MONW.
代谢性肥胖、体重正常(MONW)这一概念的出现是为了描述体重指数(BMI)正常但罹患慢性疾病风险相对较高的个体。然而,体重指数本身并不是评估内脏脂肪相关健康风险的最佳指标。甘油三酯-葡萄糖(TyG)指数被认为是胰岛素抵抗的可靠且经济有效的指标。因此,在本研究中,我们旨在确定可用于界定老年人内脏脂肪含量的TyG指数临界值,并确定这些值对预测慢性疾病的有用性。本研究共纳入了4721名韩国国民健康和营养调查的参与者,他们的年龄均不超过60岁,且无体重不足或肥胖症。MONW是根据代谢综合征(MS)的标准定义的,TyG指数是根据空腹血浆甘油三酯和葡萄糖浓度计算的。诊断出的慢性疾病包括 T2DM、高血压和非酒精性脂肪肝(NAFLD)。MS 患病率从 TyG 指数最低三等分到最高三等分依次增加。经计算,男性和女性MONW的TyG指数临界值分别为8.88和8.80。使用这些临界值定义的MONW与男性和女性非酒精性脂肪肝、T2DM和高血压的高几率相关。本研究计算出的TyG指数临界值可用于区分MONW患者和其他无肥胖症的老年人,并预测慢性疾病的风险。这些研究结果表明,TyG指数是评估MONW患者慢性病风险的一种有效且经济的方法。
{"title":"Triglyceride-glucose index is capable of identifying metabolically obese, normal-weight older individuals","authors":"Bokun Kim, Keisuke Taniguchi, Tomonori Isobe, Sechang Oh","doi":"10.1186/s40101-024-00355-6","DOIUrl":"https://doi.org/10.1186/s40101-024-00355-6","url":null,"abstract":"The concept of metabolically obese, normal weight (MONW) has emerged to describe individuals with a normal body mass index (BMI) who are at a relatively high risk of chronic diseases. However, BMI itself is a suboptimal index for the assessment of the health risks associated with visceral fat. The triglyceride-glucose (TyG) index is considered to be a reliable and cost-effective marker of insulin resistance. Therefore, in the present study, we aimed to determine the TyG index cut-off values that could be used to define MONW in older people and to determine the usefulness of these values for the prediction of chronic diseases. A total of 4,721 participants in the Korea National Health and Nutritional Examination Survey who were ≥ 60 years of age and did not have underweight or obesity were included. MONW was defined using the criteria for metabolic syndrome (MS), and the TyG index was calculated on the basis of the fasting plasma triglyceride and glucose concentrations. Chronic diseases, including T2DM, hypertension, and non-alcoholic fatty liver disease (NAFLD), were diagnosed. The prevalence of MS increased from the lowest to the highest TyG index tertile. The cut-off values of the TyG index for MONW were calculated as 8.88 and 8.80 for males and females, respectively. MONW, defined using these cut-off values, was associated with high odds ratios for NAFLD, T2DM, and hypertension in both males and females. The TyG index cut-off values calculated in the present study can be used to discriminate individuals with MONW from other older individuals without obesity and to predict the risk of chronic diseases. These findings show that the TyG index is an effective and cost-efficient method of assessing the risk of chronic diseases in people with MONW.","PeriodicalId":16768,"journal":{"name":"Journal of Physiological Anthropology","volume":"86 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139662990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The influence of the environment and lifestyle on myopia 环境和生活方式对近视的影响
IF 3.1 4区 医学 Q1 Social Sciences Pub Date : 2024-01-31 DOI: 10.1186/s40101-024-00354-7
Sayantan Biswas, Antonio El Kareh, Mariyem Qureshi, Deborah Mei Xuan Lee, Chen-Hsin Sun, Janice S.H. Lam, Seang-Mei Saw, Raymond P. Najjar
Myopia, commonly known as near-sightedness, has emerged as a global epidemic, impacting almost one in three individuals across the world. The increasing prevalence of myopia during early childhood has heightened the risk of developing high myopia and related sight-threatening eye conditions in adulthood. This surge in myopia rates, occurring within a relatively stable genetic framework, underscores the profound influence of environmental and lifestyle factors on this condition. In this comprehensive narrative review, we shed light on both established and potential environmental and lifestyle contributors that affect the development and progression of myopia. Epidemiological and interventional research has consistently revealed a compelling connection between increased outdoor time and a decreased risk of myopia in children. This protective effect may primarily be attributed to exposure to the characteristics of natural light (i.e., sunlight) and the release of retinal dopamine. Conversely, irrespective of outdoor time, excessive engagement in near work can further worsen the onset of myopia. While the exact mechanisms behind this exacerbation are not fully comprehended, it appears to involve shifts in relative peripheral refraction, the overstimulation of accommodation, or a complex interplay of these factors, leading to issues like retinal image defocus, blur, and chromatic aberration. Other potential factors like the spatial frequency of the visual environment, circadian rhythm, sleep, nutrition, smoking, socio-economic status, and education have debatable independent influences on myopia development. The environment exerts a significant influence on the development and progression of myopia. Improving the modifiable key environmental predictors like time spent outdoors and engagement in near work can prevent or slow the progression of myopia. The intricate connections between lifestyle and environmental factors often obscure research findings, making it challenging to disentangle their individual effects. This complexity underscores the necessity for prospective studies that employ objective assessments, such as quantifying light exposure and near work, among others. These studies are crucial for gaining a more comprehensive understanding of how various environmental factors can be modified to prevent or slow the progression of myopia.
近视(俗称 "近视眼")已成为一种全球性流行病,影响着全世界近三分之一的人。儿童早期近视的发病率不断上升,增加了成年后患高度近视和相关视力疾病的风险。近视发病率在相对稳定的遗传框架内激增,凸显了环境和生活方式因素对近视的深远影响。在这篇全面的叙述性综述中,我们将阐明影响近视发生和发展的既定和潜在的环境和生活方式因素。流行病学和干预性研究不断揭示出,增加户外活动时间与降低儿童近视风险之间存在着令人信服的联系。这种保护作用可能主要归因于接触自然光(即阳光)的特性和视网膜多巴胺的释放。相反,无论户外活动时间长短,过度从事近距离工作会进一步加重近视的发生。虽然这种恶化背后的确切机制还不完全清楚,但似乎涉及相对周边屈光度的变化、过度刺激调节或这些因素的复杂相互作用,从而导致视网膜图像失焦、模糊和色差等问题。其他潜在因素,如视觉环境的空间频率、昼夜节律、睡眠、营养、吸烟、社会经济地位和教育,对近视发展的独立影响还有待商榷。环境对近视的发生和发展具有重要影响。改善可改变的关键环境预测因素,如户外活动时间和从事近距离工作,可以预防或减缓近视的发展。生活方式和环境因素之间错综复杂的联系往往掩盖了研究结果,因此,要厘清它们各自的影响具有挑战性。这种复杂性凸显了前瞻性研究的必要性,这些研究采用了客观的评估方法,如量化光照和近距离工作等。这些研究对于更全面地了解如何通过改变各种环境因素来预防或减缓近视的发展至关重要。
{"title":"The influence of the environment and lifestyle on myopia","authors":"Sayantan Biswas, Antonio El Kareh, Mariyem Qureshi, Deborah Mei Xuan Lee, Chen-Hsin Sun, Janice S.H. Lam, Seang-Mei Saw, Raymond P. Najjar","doi":"10.1186/s40101-024-00354-7","DOIUrl":"https://doi.org/10.1186/s40101-024-00354-7","url":null,"abstract":"Myopia, commonly known as near-sightedness, has emerged as a global epidemic, impacting almost one in three individuals across the world. The increasing prevalence of myopia during early childhood has heightened the risk of developing high myopia and related sight-threatening eye conditions in adulthood. This surge in myopia rates, occurring within a relatively stable genetic framework, underscores the profound influence of environmental and lifestyle factors on this condition. In this comprehensive narrative review, we shed light on both established and potential environmental and lifestyle contributors that affect the development and progression of myopia. Epidemiological and interventional research has consistently revealed a compelling connection between increased outdoor time and a decreased risk of myopia in children. This protective effect may primarily be attributed to exposure to the characteristics of natural light (i.e., sunlight) and the release of retinal dopamine. Conversely, irrespective of outdoor time, excessive engagement in near work can further worsen the onset of myopia. While the exact mechanisms behind this exacerbation are not fully comprehended, it appears to involve shifts in relative peripheral refraction, the overstimulation of accommodation, or a complex interplay of these factors, leading to issues like retinal image defocus, blur, and chromatic aberration. Other potential factors like the spatial frequency of the visual environment, circadian rhythm, sleep, nutrition, smoking, socio-economic status, and education have debatable independent influences on myopia development. The environment exerts a significant influence on the development and progression of myopia. Improving the modifiable key environmental predictors like time spent outdoors and engagement in near work can prevent or slow the progression of myopia. The intricate connections between lifestyle and environmental factors often obscure research findings, making it challenging to disentangle their individual effects. This complexity underscores the necessity for prospective studies that employ objective assessments, such as quantifying light exposure and near work, among others. These studies are crucial for gaining a more comprehensive understanding of how various environmental factors can be modified to prevent or slow the progression of myopia.","PeriodicalId":16768,"journal":{"name":"Journal of Physiological Anthropology","volume":"37 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139645351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sleep and allergic diseases among young Chinese adults from the Singapore/Malaysia Cross-Sectional Genetic Epidemiology Study (SMCGES) cohort 新加坡/马来西亚横断面遗传流行病学研究(SMCGES)队列中华裔年轻人的睡眠与过敏性疾病
IF 3.1 4区 医学 Q1 Social Sciences Pub Date : 2024-01-30 DOI: 10.1186/s40101-024-00356-5
Qi Yi Ambrose Wong, Jun Jie Lim, Jun Yan Ng, Yi Ying Eliza Lim, Yang Yie Sio, Fook Tim Chew
Sleep disruption has been shown to affect immune function and thus influence allergic disease manifestation. The specific effects of sleep on allergic diseases, however, are less well-established; hence, in a unique population of young Chinese adults, we investigated the association between sleep and allergic disease. Young Chinese adults recruited from Singapore in the Singapore/Malaysia Cross-Sectional Genetic Epidemiology Study (SMCGES) were analyzed. We used the International Study of Asthma and Allergies in Childhood (ISAAC) protocol and a skin prick test to determine atopic dermatitis (AD), allergic rhinitis (AR), and asthma status. Information regarding total sleep time (TST) and sleep quality (SQ) was also obtained. Of 1558 participants with a mean age of 25.0 years (SD = 7.6), 61.4% were female, and the mean total sleep time (TST) was 6.8 h (SD = 1.1). The proportions of AD, AR, and asthma were 24.5% (393/1542), 36.4% (987/1551), and 14.7% (227/1547), respectively. 59.8% (235/393) of AD cases suffered from AD-related sleep disturbances, 37.1% (209/564) of AR cases suffered from AR-related sleep disturbances, and 25.1% (57/227) of asthma cases suffered from asthma-related sleep disturbances. Only asthma cases showed a significantly lower mean TST than those without asthma (p = 0.015). Longer TST was significantly associated with lower odds of AR (OR = 0.905, 95% CI = 0.820–0.999) and asthma (OR = 0.852, 95% CI = 0.746–0.972). Linear regression analyses showed that lower TST was significantly associated with asthma (β = − 0.18, SE = 0.076, p-value = 0.017), and AR when adjusted for AR-related sleep disturbances (β = − 0.157, SE = 0.065, p-value = 0.016). Only sleep disturbances due to AR were significantly associated with a poorer SQ (OR = 1.962, 95% CI = 1.245–3.089). We found that sleep quality, but not sleep duration was significantly poorer among AD cases, although the exact direction of influence could not be determined. In consideration of the literature coupled with our findings, we posit that TST influences allergic rhinitis rather than vice versa. Finally, the association between TST and asthma is likely mediated by asthma-related sleep disturbances, since mean TST was significantly lower among those with nighttime asthma symptoms. Future studies could consider using objective sleep measurements coupled with differential expression analysis to investigate the pathophysiology of sleep and allergic diseases.
睡眠障碍已被证明会影响免疫功能,从而影响过敏性疾病的表现。然而,睡眠对过敏性疾病的具体影响尚未得到充分证实;因此,我们在一个独特的中国年轻成年人群体中调查了睡眠与过敏性疾病之间的关系。我们分析了新加坡/马来西亚横断面遗传流行病学研究(SMCGES)中从新加坡招募的中国年轻人。我们采用国际儿童哮喘和过敏研究(ISAAC)方案和皮肤点刺试验来确定特应性皮炎(AD)、过敏性鼻炎(AR)和哮喘状态。此外,还获得了有关总睡眠时间(TST)和睡眠质量(SQ)的信息。1558 名参与者的平均年龄为 25.0 岁(SD = 7.6),61.4% 为女性,平均总睡眠时间(TST)为 6.8 小时(SD = 1.1)。患有 AD、AR 和哮喘的比例分别为 24.5%(393/1542)、36.4%(987/1551)和 14.7%(227/1547)。59.8%(235/393)的注意力缺失症病例患有与注意力缺失症相关的睡眠障碍,37.1%(209/564)的注意力缺失症病例患有与注意力缺失症相关的睡眠障碍,25.1%(57/227)的哮喘病例患有与哮喘相关的睡眠障碍。只有哮喘患者的平均 TST 明显低于非哮喘患者(p = 0.015)。较长的 TST 与较低的 AR(OR = 0.905,95% CI = 0.820-0.999)和哮喘(OR = 0.852,95% CI = 0.746-0.972)几率明显相关。线性回归分析表明,较低的 TST 与哮喘(β = - 0.18,SE = 0.076,P 值 = 0.017)和 AR 显著相关,如果调整与 AR 相关的睡眠障碍(β = - 0.157,SE = 0.065,P 值 = 0.016)。只有 AR 导致的睡眠障碍与较差的 SQ 显著相关(OR = 1.962,95% CI = 1.245-3.089)。我们发现,在注意力缺失症患者中,睡眠质量明显较差,但睡眠时间却不长,尽管无法确定确切的影响方向。考虑到相关文献和我们的研究结果,我们认为 TST 会影响过敏性鼻炎,而不是相反。最后,TST 与哮喘之间的关联很可能是由哮喘相关的睡眠障碍介导的,因为在有夜间哮喘症状的人群中,平均 TST 明显较低。未来的研究可以考虑使用客观的睡眠测量方法和差异表达分析来研究睡眠和过敏性疾病的病理生理学。
{"title":"Sleep and allergic diseases among young Chinese adults from the Singapore/Malaysia Cross-Sectional Genetic Epidemiology Study (SMCGES) cohort","authors":"Qi Yi Ambrose Wong, Jun Jie Lim, Jun Yan Ng, Yi Ying Eliza Lim, Yang Yie Sio, Fook Tim Chew","doi":"10.1186/s40101-024-00356-5","DOIUrl":"https://doi.org/10.1186/s40101-024-00356-5","url":null,"abstract":"Sleep disruption has been shown to affect immune function and thus influence allergic disease manifestation. The specific effects of sleep on allergic diseases, however, are less well-established; hence, in a unique population of young Chinese adults, we investigated the association between sleep and allergic disease. Young Chinese adults recruited from Singapore in the Singapore/Malaysia Cross-Sectional Genetic Epidemiology Study (SMCGES) were analyzed. We used the International Study of Asthma and Allergies in Childhood (ISAAC) protocol and a skin prick test to determine atopic dermatitis (AD), allergic rhinitis (AR), and asthma status. Information regarding total sleep time (TST) and sleep quality (SQ) was also obtained. Of 1558 participants with a mean age of 25.0 years (SD = 7.6), 61.4% were female, and the mean total sleep time (TST) was 6.8 h (SD = 1.1). The proportions of AD, AR, and asthma were 24.5% (393/1542), 36.4% (987/1551), and 14.7% (227/1547), respectively. 59.8% (235/393) of AD cases suffered from AD-related sleep disturbances, 37.1% (209/564) of AR cases suffered from AR-related sleep disturbances, and 25.1% (57/227) of asthma cases suffered from asthma-related sleep disturbances. Only asthma cases showed a significantly lower mean TST than those without asthma (p = 0.015). Longer TST was significantly associated with lower odds of AR (OR = 0.905, 95% CI = 0.820–0.999) and asthma (OR = 0.852, 95% CI = 0.746–0.972). Linear regression analyses showed that lower TST was significantly associated with asthma (β = − 0.18, SE = 0.076, p-value = 0.017), and AR when adjusted for AR-related sleep disturbances (β = − 0.157, SE = 0.065, p-value = 0.016). Only sleep disturbances due to AR were significantly associated with a poorer SQ (OR = 1.962, 95% CI = 1.245–3.089). We found that sleep quality, but not sleep duration was significantly poorer among AD cases, although the exact direction of influence could not be determined. In consideration of the literature coupled with our findings, we posit that TST influences allergic rhinitis rather than vice versa. Finally, the association between TST and asthma is likely mediated by asthma-related sleep disturbances, since mean TST was significantly lower among those with nighttime asthma symptoms. Future studies could consider using objective sleep measurements coupled with differential expression analysis to investigate the pathophysiology of sleep and allergic diseases.","PeriodicalId":16768,"journal":{"name":"Journal of Physiological Anthropology","volume":"12 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139586781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fructose-induced FGF21 secretion does not activate brown adipose tissue in Japanese young men: randomized cross-over and randomized controlled trials 果糖诱导的 FGF21 分泌不会激活日本年轻男性的棕色脂肪组织:随机交叉和随机对照试验
IF 3.1 4区 医学 Q1 Social Sciences Pub Date : 2024-01-04 DOI: 10.1186/s40101-023-00353-0
Haruki Kataoka, Shinsuke Nirengi, Yuka Matsui, Hirokazu Taniguchi
Human brown adipose tissue (BAT) activity is associated with lower body fatness and favorable glucose metabolism. Previous studies reported that oral fructose loading induces postprandial fibroblast growth factor 21 (FGF21) secretion. FGF21 is a known inducer of adipose tissue thermogenesis; however, the effects of diet-induced FGF21 secretion on BAT thermogenesis remain to be elucidated. The effects of both single load and daily consumption of fructose on BAT activity were examined using a randomized cross-over trial and a 2-week randomized controlled trial (RCT), respectively. In the cross-over trial, 15 young men consumed a single dose of fructose solution or water and then consumed the other on a subsequent day. The RCT enrolled 22 young men, and the participants were allocated to a group that consumed fructose and a group that consumed water daily for 2 weeks. BAT activity was analyzed using thermography with cold exposure. Plasma FGF21 level was determined by enzyme-linked immunosorbent assay. In the cross-over single-load trial, plasma FGF21 levels were significantly increased at 2 h after oral fructose load (p < 0.01); however, there was no significant difference in BAT activity between the fructose load and drinking water. The 2-week RCT revealed that both plasma FGF21 levels and BAT activity were not significantly increased by daily fructose consumption compared to water. Correlation analyses revealed that BAT activity at the baseline and the final measurements were strongly and positively associated with the RCT (r = 0.869, p < 0.001). Changes in BAT activity were significantly and negatively correlated with changes in plasma glucose levels during the 2-week intervention (r = − 0.497, p = 0.022). Oral fructose load induces a temporary increase in circulating FGF21 levels; however, this does not activate BAT thermogenesis in healthy young men. Further studies are needed to elucidate the effect of endogenous FGF21 on physiological function. This study is registered with the University Hospital Medical Information Network in Japan (number 000051761, registered 1 August 2023, retrospectively registered, https://center6.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000052680 ).
人体棕色脂肪组织(BAT)的活性与较低的体脂率和良好的糖代谢有关。以前的研究报告称,口服果糖负荷可诱导餐后成纤维细胞生长因子 21(FGF21)的分泌。FGF21 是一种已知的脂肪组织产热诱导因子;然而,饮食诱导的 FGF21 分泌对 BAT 产热的影响仍有待阐明。研究人员采用随机交叉试验和为期两周的随机对照试验(RCT),分别研究了单次摄入果糖和每天摄入果糖对BAT活动的影响。在交叉试验中,15 名年轻男性饮用了单剂量的果糖溶液或水,然后在随后的一天饮用了另一种果糖溶液或水。随机对照试验招募了 22 名年轻男性,参与者被分配到每天摄入果糖的一组和每天摄入水的一组,为期 2 周。采用冷暴露热成像技术分析了BAT活性。血浆 FGF21 水平通过酶联免疫吸附试验测定。在交叉单负荷试验中,口服果糖后 2 小时,血浆中的 FGF21 水平显著升高(p < 0.01);然而,果糖负荷组和饮水组的 BAT 活性没有显著差异。为期两周的研究表明,与饮水相比,每天摄入果糖并不会明显增加血浆中的 FGF21 水平和 BAT 活性。相关性分析表明,基线和最终测量结果显示,BAT活性与RCT密切正相关(r = 0.869,p < 0.001)。在为期 2 周的干预期间,BAT 活性的变化与血浆葡萄糖水平的变化呈显著负相关(r = - 0.497,p = 0.022)。口服果糖可诱导循环中的 FGF21 水平暂时升高,但这并不能激活健康年轻男性体内的 BAT 产热。要阐明内源性 FGF21 对生理功能的影响,还需要进一步的研究。本研究已在日本大学医院医学信息网注册(编号000051761,注册日期2023年8月1日,回顾性注册,https://center6.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000052680 )。
{"title":"Fructose-induced FGF21 secretion does not activate brown adipose tissue in Japanese young men: randomized cross-over and randomized controlled trials","authors":"Haruki Kataoka, Shinsuke Nirengi, Yuka Matsui, Hirokazu Taniguchi","doi":"10.1186/s40101-023-00353-0","DOIUrl":"https://doi.org/10.1186/s40101-023-00353-0","url":null,"abstract":"Human brown adipose tissue (BAT) activity is associated with lower body fatness and favorable glucose metabolism. Previous studies reported that oral fructose loading induces postprandial fibroblast growth factor 21 (FGF21) secretion. FGF21 is a known inducer of adipose tissue thermogenesis; however, the effects of diet-induced FGF21 secretion on BAT thermogenesis remain to be elucidated. The effects of both single load and daily consumption of fructose on BAT activity were examined using a randomized cross-over trial and a 2-week randomized controlled trial (RCT), respectively. In the cross-over trial, 15 young men consumed a single dose of fructose solution or water and then consumed the other on a subsequent day. The RCT enrolled 22 young men, and the participants were allocated to a group that consumed fructose and a group that consumed water daily for 2 weeks. BAT activity was analyzed using thermography with cold exposure. Plasma FGF21 level was determined by enzyme-linked immunosorbent assay. In the cross-over single-load trial, plasma FGF21 levels were significantly increased at 2 h after oral fructose load (p < 0.01); however, there was no significant difference in BAT activity between the fructose load and drinking water. The 2-week RCT revealed that both plasma FGF21 levels and BAT activity were not significantly increased by daily fructose consumption compared to water. Correlation analyses revealed that BAT activity at the baseline and the final measurements were strongly and positively associated with the RCT (r = 0.869, p < 0.001). Changes in BAT activity were significantly and negatively correlated with changes in plasma glucose levels during the 2-week intervention (r = − 0.497, p = 0.022). Oral fructose load induces a temporary increase in circulating FGF21 levels; however, this does not activate BAT thermogenesis in healthy young men. Further studies are needed to elucidate the effect of endogenous FGF21 on physiological function. This study is registered with the University Hospital Medical Information Network in Japan (number 000051761, registered 1 August 2023, retrospectively registered, https://center6.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000052680 ).","PeriodicalId":16768,"journal":{"name":"Journal of Physiological Anthropology","volume":"34 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139093719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Altered neurophysiological responses during empathy for pain in insomnia: evidence from an EEG study in non-clinical samples 失眠症患者对疼痛产生移情时的神经生理反应改变:非临床样本脑电图研究的证据
IF 3.1 4区 医学 Q1 Social Sciences Pub Date : 2024-01-03 DOI: 10.1186/s40101-023-00351-2
Siyu Li, Meiheng He, Li Lin, Qingwei Chen, Taotao Ru, Guofu Zhou
This study aims to investigate the behavioral and neurophysiological changes accompanying the empathy for pain among individuals with insomnia in nonclinical samples, which has been scarcely explored in the existing literature despite the deleterious effects of sleep disturbance on social behavior, and interactions had been well-documented. Twenty-one individuals with insomnia in nonclinical samples and 20 healthy individuals as normal controls participated in the study. Electroencephalograph (EEG) was continuously recorded, while the participants underwent an empathy for pain task. Subjective ratings of pain for painful and non-painful images revealed no statistically significant differences between the insomnia and control groups. The painful images induced a smaller P2 compared to non-painful images in the insomnia group, whereas no such difference was revealed for the controls. Moreover, a higher power density of the alpha and theta2 bands in the posterior brain regions was found in the insomnia group compared to the control group. These findings suggest that individuals with insomnia exhibit altered neurophysiological responses to pain stimuli and a lower capacity to share empathy for pain. These alterations may be associated with changes in attentional mechanisms.
本研究旨在探讨非临床样本中的失眠症患者在对疼痛产生移情时的行为和神经生理学变化,尽管睡眠障碍对社会行为和互动的有害影响已被充分证实,但现有文献中对这一问题的探讨却很少。21 名非临床样本中的失眠症患者和 20 名健康人作为正常对照组参与了这项研究。研究人员连续记录脑电图(EEG),同时对参与者进行疼痛移情任务。对疼痛和非疼痛图像的主观疼痛评分显示,失眠组和对照组之间没有显著的统计学差异。与非痛苦图像相比,痛苦图像在失眠组中引起的 P2 值较小,而在对照组中则没有发现这种差异。此外,与对照组相比,失眠组大脑后部区域α和θ2波段的功率密度更高。这些研究结果表明,失眠症患者对疼痛刺激的神经生理反应发生了改变,对疼痛的共鸣能力降低。这些改变可能与注意力机制的变化有关。
{"title":"Altered neurophysiological responses during empathy for pain in insomnia: evidence from an EEG study in non-clinical samples","authors":"Siyu Li, Meiheng He, Li Lin, Qingwei Chen, Taotao Ru, Guofu Zhou","doi":"10.1186/s40101-023-00351-2","DOIUrl":"https://doi.org/10.1186/s40101-023-00351-2","url":null,"abstract":"This study aims to investigate the behavioral and neurophysiological changes accompanying the empathy for pain among individuals with insomnia in nonclinical samples, which has been scarcely explored in the existing literature despite the deleterious effects of sleep disturbance on social behavior, and interactions had been well-documented. Twenty-one individuals with insomnia in nonclinical samples and 20 healthy individuals as normal controls participated in the study. Electroencephalograph (EEG) was continuously recorded, while the participants underwent an empathy for pain task. Subjective ratings of pain for painful and non-painful images revealed no statistically significant differences between the insomnia and control groups. The painful images induced a smaller P2 compared to non-painful images in the insomnia group, whereas no such difference was revealed for the controls. Moreover, a higher power density of the alpha and theta2 bands in the posterior brain regions was found in the insomnia group compared to the control group. These findings suggest that individuals with insomnia exhibit altered neurophysiological responses to pain stimuli and a lower capacity to share empathy for pain. These alterations may be associated with changes in attentional mechanisms.","PeriodicalId":16768,"journal":{"name":"Journal of Physiological Anthropology","volume":"42 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139082523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Utility of salivary cortisol profile as a predictive biomarker in nurses’ turnover risk: a preliminary study 唾液皮质醇图谱作为预测护士离职风险的生物标志物的效用:一项初步研究
IF 3.1 4区 医学 Q1 Social Sciences Pub Date : 2024-01-02 DOI: 10.1186/s40101-023-00349-w
Shinya Yamaguchi, Tomoko Fujita, Shintaro Kato, Yuichi Yoshimitsu, Yoichi M. Ito, Rika Yano
Predicting nurse turnover risk is crucial due to the global nursing shortage; however, existing predictors, such as fatigue and burnout, lack objectivity. Salivary cortisol is a non-invasive marker of stress and fatigue, but its utility in predicting nurse turnover risk is unknown. We examined whether salivary cortisol profiles across three different day shifts in a month are predictors of the extent of nurses’ reluctance to stay in their current jobs. This preliminary longitudinal study followed forty female nurses who engaged in shift work at a university hospital for 3 months. Data at enrollment were collected including demographics, working conditions, chronic fatigue (the Japanese version of the Occupational Fatigue/Exhaustion Recovery Scale), and burnout (Japanese Burnout scale). Salivary cortisol was measured before the three different day shifts (after awakening) during the first month, and the means of these measurements were used as the cortisol profile. The extent of reluctance to stay was assessed using the numerical rating scale at 3 months. Among the forty female nurses (mean [SD] age, 28.3 [5.1]), all completed follow-up and were included in the analysis. The cortisol profile was associated with the extent of reluctance to stay (P = 0.017), and this association was significant despite adjustments for chronic fatigue and burnout (P = 0.005). A multiple regression model with chronic fatigue, burnout, and job tenure explained 41.5% of the variation in reluctance to stay. When the cortisol profile was added to this model, the association of the cortisol profile was significant (P = 0.006) with an R2 of 0.529 (ΔR2 = 0.114). This preliminary study conducted in an actual clinical setting indicated the potential of the salivary cortisol profile across three different day shifts in a month to predict nurses’ reluctance to stay in their current jobs. The combination of subjective indicators and the cortisol profile would be useful in predicting nurses' turnover risk.
由于全球护士短缺,预测护士离职风险至关重要;然而,疲劳和职业倦怠等现有预测指标缺乏客观性。唾液皮质醇是压力和疲劳的非侵入性标志物,但其在预测护士离职风险方面的作用尚不清楚。我们研究了一个月内三个不同日班的唾液皮质醇曲线是否能预测护士不愿留在现有工作岗位的程度。这项初步纵向研究对一家大学医院中从事轮班工作的 40 名女护士进行了为期 3 个月的跟踪调查。注册时收集的数据包括人口统计学、工作条件、慢性疲劳(日语版职业疲劳/疲惫恢复量表)和职业倦怠(日语版职业倦怠量表)。在第一个月的三个不同日班前(起床后)测量了唾液皮质醇,这些测量值的平均值被用作皮质醇曲线。在 3 个月时,使用数字评分量表对不愿留下来的程度进行评估。在 40 名女护士(平均 [SD] 年龄,28.3 [5.1])中,所有人都完成了随访并纳入了分析。皮质醇特征与不愿留院的程度有关(P = 0.017),尽管对慢性疲劳和职业倦怠进行了调整(P = 0.005),但这种关联仍然显著。一个包含慢性疲劳、职业倦怠和工作年限的多元回归模型可以解释 41.5% 的不愿留任的变化。当将皮质醇曲线加入该模型时,皮质醇曲线的相关性显著(P = 0.006),R2 为 0.529(ΔR2 = 0.114)。这项在实际临床环境中进行的初步研究表明,唾液皮质醇图谱在一个月内三个不同日班的情况下,有可能预测护士是否愿意继续从事目前的工作。主观指标与皮质醇曲线的结合将有助于预测护士的离职风险。
{"title":"Utility of salivary cortisol profile as a predictive biomarker in nurses’ turnover risk: a preliminary study","authors":"Shinya Yamaguchi, Tomoko Fujita, Shintaro Kato, Yuichi Yoshimitsu, Yoichi M. Ito, Rika Yano","doi":"10.1186/s40101-023-00349-w","DOIUrl":"https://doi.org/10.1186/s40101-023-00349-w","url":null,"abstract":"Predicting nurse turnover risk is crucial due to the global nursing shortage; however, existing predictors, such as fatigue and burnout, lack objectivity. Salivary cortisol is a non-invasive marker of stress and fatigue, but its utility in predicting nurse turnover risk is unknown. We examined whether salivary cortisol profiles across three different day shifts in a month are predictors of the extent of nurses’ reluctance to stay in their current jobs. This preliminary longitudinal study followed forty female nurses who engaged in shift work at a university hospital for 3 months. Data at enrollment were collected including demographics, working conditions, chronic fatigue (the Japanese version of the Occupational Fatigue/Exhaustion Recovery Scale), and burnout (Japanese Burnout scale). Salivary cortisol was measured before the three different day shifts (after awakening) during the first month, and the means of these measurements were used as the cortisol profile. The extent of reluctance to stay was assessed using the numerical rating scale at 3 months. Among the forty female nurses (mean [SD] age, 28.3 [5.1]), all completed follow-up and were included in the analysis. The cortisol profile was associated with the extent of reluctance to stay (P = 0.017), and this association was significant despite adjustments for chronic fatigue and burnout (P = 0.005). A multiple regression model with chronic fatigue, burnout, and job tenure explained 41.5% of the variation in reluctance to stay. When the cortisol profile was added to this model, the association of the cortisol profile was significant (P = 0.006) with an R2 of 0.529 (ΔR2 = 0.114). This preliminary study conducted in an actual clinical setting indicated the potential of the salivary cortisol profile across three different day shifts in a month to predict nurses’ reluctance to stay in their current jobs. The combination of subjective indicators and the cortisol profile would be useful in predicting nurses' turnover risk.","PeriodicalId":16768,"journal":{"name":"Journal of Physiological Anthropology","volume":"21 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139080157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alleviation of acute stress response by black pepper aroma administration 施用黑胡椒香气缓解急性应激反应
IF 3.1 4区 医学 Q1 Social Sciences Pub Date : 2024-01-02 DOI: 10.1186/s40101-023-00352-1
E. A. Chayani Dilrukshi, Yuta Nishiyama, Kanetoshi Ito, Shusaku Nomura
Black pepper is one of the most popular spices globally. As black pepper essential oil has not yet been used in the context of aromatherapy, this study examined the effect of black pepper aroma on cardiac and peripheral autonomic nervous system (ANS) activity under stressful conditions using an olfactometer to administer aroma in a precise and controlled manner to ensure reproducibility. A within-participant design experiment was conducted with 20 male university students who performed a 30-min calculation task as a short-term stressor under three aroma conditions: black pepper, ginger, and dipropylene glycol (DPG) (scentless air as a control). Each aroma was sporadically delivered (first 20 s of each 1-min interval) with the olfactometer during the task. Electrocardiograms and skin conductance level (SCL) were measured to evaluate ANS's physiological acute stress response. Subjective evaluations for the given stressful task and impressions on the types of aromas were assessed. The physiological acute stress response induced by the short-term stressor, which is characterized by the enhancement of the heart rate (HR) and SCL and decreases in the heart rate variability (HRV), was suppressed with black pepper: the increase in HR and reduction in HRV from the baseline were 38.9% (p = 0.048 when compared with DPG) and 32.9% smaller (p = 0.002 for multiple comparisons) than those in DPG, respectively, and the increase of SCL was 15.5% smaller (p = 0.005 for multiple comparisons) than that in ginger. However, there was no significant difference in subjective scores among the conditions. Although black pepper is a stimulative agent, the study findings showed that black pepper aroma alleviated the physiological acute stress response, which can be beneficial in aromatherapy under stressful conditions.
黑胡椒是全球最受欢迎的香料之一。由于黑胡椒精油尚未被用于芳香疗法,本研究使用嗅觉仪以精确可控的方式施用香气,以确保可重复性,研究了黑胡椒香气对压力条件下心脏和外周自律神经系统(ANS)活动的影响。在黑胡椒、生姜和二甘醇(DPG)三种香气条件下(无香气空气作为对照),20 名男性大学生进行了 30 分钟的计算任务,以此作为短期压力源。在完成任务期间,每种香气都会通过嗅觉仪零星散发(每间隔 1 分钟的前 20 秒)。测量心电图和皮肤电导水平(SCL)以评估 ANS 的生理急性应激反应。还评估了对特定压力任务的主观评价以及对香气类型的印象。短期压力诱导的生理急性压力反应表现为心率(HR)和 SCL 的升高以及心率变异性(HRV)的降低,而黑胡椒则抑制了这种反应:与基线相比,心率的升高和心率变异性的降低分别为 38.9%(与 DPG 比较,p = 0.048)和 32.9%(多重比较,p = 0.002),SCL 的增加比生姜小 15.5%(多重比较,p = 0.005)。然而,不同条件下的主观评分没有明显差异。虽然黑胡椒是一种刺激性物质,但研究结果表明,黑胡椒香气能缓解生理上的急性应激反应,这在应激条件下的芳香疗法中是有益的。
{"title":"Alleviation of acute stress response by black pepper aroma administration","authors":"E. A. Chayani Dilrukshi, Yuta Nishiyama, Kanetoshi Ito, Shusaku Nomura","doi":"10.1186/s40101-023-00352-1","DOIUrl":"https://doi.org/10.1186/s40101-023-00352-1","url":null,"abstract":"Black pepper is one of the most popular spices globally. As black pepper essential oil has not yet been used in the context of aromatherapy, this study examined the effect of black pepper aroma on cardiac and peripheral autonomic nervous system (ANS) activity under stressful conditions using an olfactometer to administer aroma in a precise and controlled manner to ensure reproducibility. A within-participant design experiment was conducted with 20 male university students who performed a 30-min calculation task as a short-term stressor under three aroma conditions: black pepper, ginger, and dipropylene glycol (DPG) (scentless air as a control). Each aroma was sporadically delivered (first 20 s of each 1-min interval) with the olfactometer during the task. Electrocardiograms and skin conductance level (SCL) were measured to evaluate ANS's physiological acute stress response. Subjective evaluations for the given stressful task and impressions on the types of aromas were assessed. The physiological acute stress response induced by the short-term stressor, which is characterized by the enhancement of the heart rate (HR) and SCL and decreases in the heart rate variability (HRV), was suppressed with black pepper: the increase in HR and reduction in HRV from the baseline were 38.9% (p = 0.048 when compared with DPG) and 32.9% smaller (p = 0.002 for multiple comparisons) than those in DPG, respectively, and the increase of SCL was 15.5% smaller (p = 0.005 for multiple comparisons) than that in ginger. However, there was no significant difference in subjective scores among the conditions. Although black pepper is a stimulative agent, the study findings showed that black pepper aroma alleviated the physiological acute stress response, which can be beneficial in aromatherapy under stressful conditions.","PeriodicalId":16768,"journal":{"name":"Journal of Physiological Anthropology","volume":"37 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139078700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How staying in a gymnasium affects sleep and bed climate in children 健身房如何影响儿童的睡眠和床的温度
IF 3.1 4区 医学 Q1 Social Sciences Pub Date : 2024-01-02 DOI: 10.1186/s40101-023-00350-3
Kazue Okamoto-Mizuno, Koh Mizuno
We investigated the relationship between sleep, ambient climate, and bed climate in school-aged children during a one-night stay in a simulated shelter in a gymnasium to demonstrate the effect of ambient climate, and bed climate on sleep. We obtained measurements during a one-night stay in a school gymnasium (C), days before C (BC), on the day after (A1), and on the second day after C (A2) in 13 healthy school-aged children during summer. Sleep was evaluated using an actigraph, and the temperature and humidity of the bedrooms in the participants’ homes and in the gymnasium were monitored for 3 days before and after C. The bed climate of the chest and foot areas was measured for two nights before and after C. The participants were asked to report on their subjective sleep estimations and thermal sensations two nights before and after C. The ambient temperature in C was significantly higher than that in BC at the initial 180 min, while it significantly decreased compared to A1 and A2 in the last 100 min. The ambient humidity was significantly higher in both C and BC compared to A1 and A2. The sleep efficiency index decreased significantly in C (43±4.8%) compared to other conditions. Sleep time was significantly shorter in C than in other conditions during the initial 195 min. The increase in the bed climate temperature of the chest area in C was significantly delayed compared to that in the other conditions, around the initial 30 min after the lights were off. Subjective estimation revealed that in C, 85% of the participants were out of their sleeping bag at sleep onset, and their sleep was disturbed by heat (77%). Our study revealed that the disturbed sleep patterns observed with children in a simulated shelter may be related to a delayed increase in bed climate temperature in the chest area. This delayed increase could be related to the children not entering the sleeping bag and a delayed chest skin temperature increase during the sleep onset period.
我们调查了学龄儿童在体育馆模拟避难所中停留一晚期间睡眠、环境气候和床铺气候之间的关系,以证明环境气候和床铺气候对睡眠的影响。我们在暑期对 13 名健康学龄儿童在学校体育馆(C)、C 前几天(BC)、C 后一天(A1)和 C 后第二天(A2)的一夜住宿进行了测量。使用动觉仪对睡眠情况进行了评估,并监测了 C 前后 3 天参与者家中卧室和体育馆的温度和湿度,还测量了 C 前后两晚胸部和脚部的床温。与 A1 和 A2 相比,C 和 BC 的环境湿度都明显较高。与其他条件相比,C 的睡眠效率指数(43±4.8%)明显下降。在最初的 195 分钟内,C 条件下的睡眠时间明显短于其他条件。在熄灯后的最初 30 分钟左右,与其他条件相比,C 条件下胸部区域的床温上升明显延迟。主观估计显示,在 C 条件下,85% 的参与者在睡眠开始时离开睡袋,他们的睡眠受到热量的干扰(77%)。我们的研究表明,在模拟避难所中观察到的儿童睡眠模式紊乱可能与胸部区域床气候温度的延迟上升有关。这种延迟上升可能与儿童没有进入睡袋以及睡眠开始期间胸部皮肤温度延迟上升有关。
{"title":"How staying in a gymnasium affects sleep and bed climate in children","authors":"Kazue Okamoto-Mizuno, Koh Mizuno","doi":"10.1186/s40101-023-00350-3","DOIUrl":"https://doi.org/10.1186/s40101-023-00350-3","url":null,"abstract":"We investigated the relationship between sleep, ambient climate, and bed climate in school-aged children during a one-night stay in a simulated shelter in a gymnasium to demonstrate the effect of ambient climate, and bed climate on sleep. We obtained measurements during a one-night stay in a school gymnasium (C), days before C (BC), on the day after (A1), and on the second day after C (A2) in 13 healthy school-aged children during summer. Sleep was evaluated using an actigraph, and the temperature and humidity of the bedrooms in the participants’ homes and in the gymnasium were monitored for 3 days before and after C. The bed climate of the chest and foot areas was measured for two nights before and after C. The participants were asked to report on their subjective sleep estimations and thermal sensations two nights before and after C. The ambient temperature in C was significantly higher than that in BC at the initial 180 min, while it significantly decreased compared to A1 and A2 in the last 100 min. The ambient humidity was significantly higher in both C and BC compared to A1 and A2. The sleep efficiency index decreased significantly in C (43±4.8%) compared to other conditions. Sleep time was significantly shorter in C than in other conditions during the initial 195 min. The increase in the bed climate temperature of the chest area in C was significantly delayed compared to that in the other conditions, around the initial 30 min after the lights were off. Subjective estimation revealed that in C, 85% of the participants were out of their sleeping bag at sleep onset, and their sleep was disturbed by heat (77%). Our study revealed that the disturbed sleep patterns observed with children in a simulated shelter may be related to a delayed increase in bed climate temperature in the chest area. This delayed increase could be related to the children not entering the sleeping bag and a delayed chest skin temperature increase during the sleep onset period.","PeriodicalId":16768,"journal":{"name":"Journal of Physiological Anthropology","volume":"78 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139078750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Physiological Anthropology
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1