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Associations between the extent of maxillary defects and oral functions in patients with maxillectomy and definitive obturators. 上颌切除和最终闭孔患者上颌缺损程度与口腔功能的关系。
IF 3.4 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-06 DOI: 10.2186/jpr.JPR_D_25_00167
Takayuki Kosaka, Emiri Ishii, Momoyo Kida, Shuri Fushida, Satoko Takeuchi, Risa Hiramatsu, Kotaro Higashi, Kazunori Ikebe

Purpose: We aimed to verify the hypothesis that patients who undergo prosthetic treatment with a definitive obturator following maxillectomy for oral tumors show decreased oral functions when the maxillary defects are extensive.

Methods: This study comprised 77 patients (46 men, 31 women; mean age, 71.0 years) who underwent prosthetic treatment with definitive obturators designed to restore maxillary defects following maxillectomy owing to an oral tumor. Oral function, masticatory performance, maximum bite force, tongue pressure, and tongue-lip motor function (oral diadochokinesis /pa/, /ta/, /ka/) were evaluated. The extent of maxillary defects was evaluated based on Aramany's classification. The maxillary defects were classified into three groups, namely, no oroantral communication (NOC), small oroantral communication (SOC), and large oroantral communication (LOC) groups. Multiple regression analyses were performed with each oral function as the objective variable and age, sex, maximal mouth opening, history of radiotherapy, number of functional teeth, and the extent of the maxillary defect as explanatory variables.

Results: The number of functional teeth and LOC were significant as explanatory variables for masticatory performance, while sex, number of functional teeth, and LOC were significant as explanatory variables for maximum bite force. Regarding other oral functions, the extent of the jaw defect was not significant as an explanatory variable.

Conclusions: In patients with maxillary defects wearing definitive obturators, a defect exceeding half of the palate and communicating with the nasal cavity was significantly associated with lower masticatory performance and maximum bite force.

目的:我们的目的是验证一个假设,即当上颌肿瘤广泛缺损时,患者在上颌肿瘤切除术后接受最终闭孔修复治疗会出现口腔功能下降。方法:本研究纳入了77例患者(男性46例,女性31例,平均年龄71.0岁),这些患者在口腔肿瘤导致的上颌切除后接受了最终闭孔修复假体治疗。评估口腔功能、咀嚼性能、最大咬合力、舌压和舌唇运动功能(口腔diadochkinesis /pa/, /ta/, /ka/)。根据Aramany分类对上颌缺损程度进行评价。将上颌缺损分为无口颌面连通(NOC)组、小口颌面连通(SOC)组和大口颌面连通(LOC)组。以各项口腔功能为客观变量,以年龄、性别、最大开口、放疗史、功能牙数、上颌缺损程度为解释变量,进行多元回归分析。结果:功能牙数和LOC作为咀嚼性能的解释变量显著,性别、功能牙数和LOC作为最大咬合力的解释变量显著。至于其他的口腔功能,颌骨缺损的程度并不是一个显著的解释变量。结论:上颌缺损患者佩戴确定性闭孔器,缺损面积超过上颚一半且与鼻腔相通,其咀嚼功能和最大咬合力明显降低。
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引用次数: 0
The effects of simulated gastric acid on the mechanical, optical, and physicochemical properties of different esthetic CAD-CAM materials. 模拟胃酸对不同美学CAD-CAM材料力学、光学和物理化学性质的影响。
IF 3.4 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-06 DOI: 10.2186/jpr.JPR_D_25_00215
Ece Ucar Basol, Ilgin Dogan, Ferhan Egilmez, Lippo Lassila, Isil Cekic-Nagas

Purpose: To investigate the effects of coffee and orange juice on 3 different esthetic ceramic materials regarding color changes, Vickers microhardness, and solubility & sorption changes among patients with reflux.

Methods: A glass-ceramic material (IPS Emax CAD), a polymer-infiltrated ceramic material (Vita Enamic), and a nano-hybrid ceramic material (Cerasmart) were selected for this study (n=32/group). Following the polishing procedure, all the samples were immersed in artificial saliva for 21 days. Half the samples were assigned to the control group and exposed only to artificial saliva (pH 7.3). The remaining 16 samples were exposed to saliva or simulated gastric acid. Sixteen samples from each group were exposed to gastric acid 3 times daily for 30 seconds. The color, Vickers microhardness, and solubility & sorption were then measured. Following this procedure, the samples were exposed to coffee and orange juice (n=8/per group). The samples were exposed to the solutions for 16 hours and 48 minutes to simulate 21 days of consumption. Final measurements were then obtained. Statistical significance was determined using Levene's test to compare variances, and three-way analysis of variance (ANOVA) followed by Tukey's post-hoc test, Welch's ANOVA, and Games-Howell's test were applied to reveal differences between groups.

Results: According to ANOVA, restorative material type and immersion media had a significant effect on color change (P < 0.001), microhardness (P < 0.001), and solubility & sorption (P < 0.001).

Conclusions: The choice of material is crucial for erosion-prone patients.

目的:探讨咖啡和橙汁对3种不同审美陶瓷材料在反流患者中的颜色变化、维氏显微硬度、溶解度和吸附性变化的影响。方法:选择玻璃陶瓷材料(IPS Emax CAD)、聚合物浸润陶瓷材料(Vita Enamic)和纳米杂化陶瓷材料(Cerasmart),每组32人。抛光后,将所有样品浸泡在人工唾液中21天。一半的样本被分配到对照组,只暴露于人工唾液(pH值7.3)。剩下的16个样本暴露在唾液或模拟胃酸中。每组16个样本每天暴露于胃酸3次,持续30秒。然后测定颜色、维氏显微硬度、溶解度和吸附性。按照这个程序,这些样本暴露在咖啡和橙汁中(n=8/每组)。将样品暴露在溶液中16小时48分钟,以模拟21天的消耗。然后得到最终的测量值。采用Levene检验比较差异,采用三向方差分析(ANOVA),随后采用Tukey事后检验、Welch方差分析和Games-Howell检验来揭示组间差异。结果:根据方差分析,修复材料类型和浸泡介质对颜色变化(P < 0.001)、显微硬度(P < 0.001)、溶解度和吸附性(P < 0.001)有显著影响。结论:材料的选择对糜烂易感患者至关重要。
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引用次数: 0
Influence of residual ridge morphology and manufacturing methods on the trueness of digitally fabricated denture bases of the mandible. 残脊形态及制作方法对数字义齿基托正确率的影响。
IF 3.4 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-06 DOI: 10.2186/jpr.JPR_D_25_00085
Atsuo Nakanishi, Yutaro Oyamada, Yuka Sasaki, Kazuhiro Kon

Purpose: To evaluate the trueness of denture bases fabricated using digital light processing (DLP) and milling methods using three-dimensional (3D) models with varying residual ridge morphologies.

Methods: Edentulous mandibular 3D models representing a well-rounded ridge (WR), knife-edge ridge (KR), and flat ridge (FR) were designed using computer-aided design (CAD) software. Denture bases for these models were created using dental CAD software and fabricated via DLP 3D printing at build angles of 0 and 45 degrees (DLP0 and DLP45) and by milling (MIL). A total of 90 denture bases were fabricated, with 10 bases per model-method combination. These bases were digitized and compared to their original CAD data to assess the adaptation across three regions: denture border, alveolar ridge, and retromolar pad. Measurements were performed at three time points: before water storage, after 1 day of water storage, and after 7 days of water storage.

Results: The MIL bases exhibited significantly lower 3D surface deviations than the DLP0 and DLP45 bases. The KR models generally exhibited greater 3D surface deviations than the WR and FR models. Temporal changes in the denture bases were significant across almost all ridge types and manufacturing methods.

Conclusions: The trueness of digitally fabricated denture bases is influenced by the residual ridge morphology and manufacturing method. Milling demonstrated superior trueness compared to DLP. Temporal dimensional changes were observed in almost all the bases.

目的:利用具有不同残牙形态的三维模型,评价采用数字光处理(DLP)和铣削方法制作的义齿基托的真实性。方法:采用计算机辅助设计软件(CAD)设计无牙下颌圆脊(WR)、刀口脊(KR)和平面脊(FR)三维模型。这些模型的义齿基托使用牙科CAD软件创建,并通过DLP 3D打印以0和45度的构建角(DLP0和DLP45)和铣削(MIL)制作。共制作90个义齿基托,每个模型-方法组合10个基托。这些基础被数字化,并与原始CAD数据进行比较,以评估三个区域的适应性:义齿边界、牙槽嵴和臼齿后垫。在三个时间点进行测量:蓄水前、蓄水1天后和蓄水7天后。结果:与DLP0和DLP45相比,MIL基的三维表面偏差明显降低。与WR和FR模型相比,KR模型普遍表现出更大的三维表面偏差。义齿基托的颞部变化在几乎所有基托类型和制造方法中都是显著的。结论:数字义齿基托的正确率受残牙形态和制作方法的影响。与DLP相比,铣削显示出更高的准确性。在几乎所有的碱基中都观察到时间维度的变化。
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引用次数: 0
Elucidation of the bonding mechanism of acidic and sulfur-based monomers to heat-treated copper-containing gold alloys. 酸性和硫基单体与热处理含铜金合金的键合机理的阐明。
IF 3.4 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-05 DOI: 10.2186/jpr.JPR_D_25_00233
Kosuke Takehana, Haruto Hiraba, Hiroyasu Koizumi, Takayuki Yoneyama

Purpose: To elucidate how the combination of acidic and sulfur-based monomers enhances bonding to oxidized noble metal alloy surfaces.

Methods: Two types of gold alloys were used: one with a low copper content (DG) and the other with a high copper content (IV). Three primers were used: a sulfur-based monomer primer (VP), a phosphate-based acidic monomer primer (PZ), and a combination of both (MC). Two conditions were used: heated and non-heated. The shear bond strengths before and after thermocycling were determined and compared for each condition. Surface chemical analysis was performed using X-ray photoelectron spectroscopy (XPS).

Results: After thermocycling, the bond strength of MC was significantly higher than that of the VP under all conditions. In the comparison of alloys under heating conditions, IV showed a significantly higher bond strength than that of DG for the PZ and MC groups. XPS revealed peaks attributed to copper oxide (CuO) formation on the heated IV surface.

Conclusions: Multipurpose primers are effective for bonding oxidized noble metal alloys and acrylic resins. The formation of CuO improves the performance of 10-methacryloyloxydecyl dihydrogen phosphate, and its combination with sulfur-based monomers is particularly effective for noble metal alloy surfaces with high copper content.

目的:阐明酸性和硫基单体的结合如何增强氧化贵金属合金表面的结合。方法:采用低铜含量(DG)和高铜含量(IV)两种金合金。使用了三种引物:硫基单体引物(VP)、磷酸基酸性单体引物(PZ)和两者的组合(MC)。实验采用加热和不加热两种条件。测定了每种条件下热循环前后的剪切粘结强度,并进行了比较。用x射线光电子能谱(XPS)进行表面化学分析。结果:经热循环后,MC在各条件下的结合强度均显著高于VP。在加热条件下的合金对比中,IV对PZ和MC组的结合强度明显高于DG。XPS显示了在加热后的IV表面形成的氧化铜(CuO)峰。结论:多用途处理剂对氧化贵金属合金与丙烯酸树脂的粘接效果较好。CuO的形成提高了10-甲基丙烯酰氧癸基磷酸二氢的性能,其与硫基单体的结合对铜含量高的贵金属合金表面特别有效。
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引用次数: 0
Digital fabrication of obturators with immediate optimized facial support for extensive maxillectomy using the existing maxillary contour. 利用现有的上颌轮廓,立即优化面部支持的数字制造封闭孔,用于广泛的上颌切除术。
IF 3.4 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-05 DOI: 10.2186/jpr.JPR_D_25_00096
Ziyan Guo, Shiwei Song, Zhiwen Li, Feichi Wang, Huayu Fang, Jiachen Song, Yimin Zhao, Shizhu Bai

Purpose: Extensive maxillectomy may result in rapid contour changes in the unsupported facial tissue, causing irreversible and severe aesthetic deformities. This technical report details a novel digital workflow for the fabrication of obturators with immediate facial support consistent with the existing maxillary contour.

Methods: Preoperative digital impressions were obtained using an intraoral scanner (IOS). A three-dimensional (3D) model of the presurgical maxillofacial hard tissue was constructed using cone-beam computed tomography (CBCT) and aligned with the IOS data. Surgical planning data were used to guide the separation and fusion of anatomical reference data for obturator design from the CBCT and IOS data. The obturator was designed using dental design software, and the existing maxillary morphology for facial support was transferred to the obturator. After the surgical resection, an immediate obturator with a surgical pack was placed at the defect site.

Conclusions: The implementation of a fully digital workflow demonstrated the potential to streamline the complex procedure traditionally required to restore harmonious facial contour support through the transfer of maxillary morphology to the immediate obturator. This method offers a promising and viable alternative to conventional techniques, with the potential to minimize long-term aesthetic compromise, facilitate adaptation and functional restoration, and simplify postoperative prosthetic care.

目的:广泛的上颌切除术可能导致无支撑的面部组织的轮廓迅速改变,造成不可逆的和严重的美学畸形。本技术报告详细介绍了一种新颖的数字工作流程,用于制造与现有上颌轮廓一致的即时面部支持的闭孔。方法:术前使用口内扫描仪(IOS)获得数字印痕。采用锥形束ct (cone-beam computed tomography, CBCT)建立手术前颌面部硬组织的三维(3D)模型,并与IOS数据对齐。手术计划数据用于指导从CBCT和IOS数据中分离和融合闭孔设计的解剖学参考数据。采用牙科设计软件设计闭孔,将现有的上颌面部支撑形态转移到闭孔上。手术切除后,在缺损部位用手术包置入即时闭孔。结论:全数字化工作流程的实施显示了简化传统上需要通过上颌形态转移到直接闭孔来恢复和谐面部轮廓支持的复杂程序的潜力。该方法为传统技术提供了一种有前途和可行的替代方法,具有最大限度地减少长期美学损害,促进适应和功能恢复,简化术后假体护理的潜力。
{"title":"Digital fabrication of obturators with immediate optimized facial support for extensive maxillectomy using the existing maxillary contour.","authors":"Ziyan Guo, Shiwei Song, Zhiwen Li, Feichi Wang, Huayu Fang, Jiachen Song, Yimin Zhao, Shizhu Bai","doi":"10.2186/jpr.JPR_D_25_00096","DOIUrl":"https://doi.org/10.2186/jpr.JPR_D_25_00096","url":null,"abstract":"<p><strong>Purpose: </strong>Extensive maxillectomy may result in rapid contour changes in the unsupported facial tissue, causing irreversible and severe aesthetic deformities. This technical report details a novel digital workflow for the fabrication of obturators with immediate facial support consistent with the existing maxillary contour.</p><p><strong>Methods: </strong>Preoperative digital impressions were obtained using an intraoral scanner (IOS). A three-dimensional (3D) model of the presurgical maxillofacial hard tissue was constructed using cone-beam computed tomography (CBCT) and aligned with the IOS data. Surgical planning data were used to guide the separation and fusion of anatomical reference data for obturator design from the CBCT and IOS data. The obturator was designed using dental design software, and the existing maxillary morphology for facial support was transferred to the obturator. After the surgical resection, an immediate obturator with a surgical pack was placed at the defect site.</p><p><strong>Conclusions: </strong>The implementation of a fully digital workflow demonstrated the potential to streamline the complex procedure traditionally required to restore harmonious facial contour support through the transfer of maxillary morphology to the immediate obturator. This method offers a promising and viable alternative to conventional techniques, with the potential to minimize long-term aesthetic compromise, facilitate adaptation and functional restoration, and simplify postoperative prosthetic care.</p>","PeriodicalId":16887,"journal":{"name":"Journal of prosthodontic research","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145900752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fracture toughness evaluation of zirconia ceramics using nonlinear dynamic finite element analysis. 基于非线性动态有限元分析的氧化锆陶瓷断裂韧性评价。
IF 3.4 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-05 DOI: 10.2186/jpr.JPR_D_25_00242
Okkar Kyaw, Satoshi Yamaguchi, Manabu Kanazawa, Jan De Munck, Pong Pongprueksa, Jef Vleugels, Bart Van Meerbeek, Fei Zhang, Masanao Inokoshi

Purpose: The purpose of this study was to establish chevron-notched beam (CNB) finite element analysis (FEA) models to investigate the fracture toughness of zirconia ceramics.

Methods: Experimental four-point flexural strength data (n = 9; previously published) for 3 mol% yttria-stabilized tetragonal zirconia polycrystals (3Y-TZP; 3M Oral Care, Seefeld, Germany) were combined with numerical data (calculated using the inverse finite element method) to evaluate the input material properties of the CNB-FEA models. These models (n = 8) were then simulated and validated against the CNB test data of specimens with the same geometries (n = 8). The validation criteria included the margin of error, coefficient of determination, and linear regression. FEA was used to evaluate the volumetric strain distribution during deformation.

Results: 3Y-TZP has static elastic modulus and fracture strain values of 144.5 GPa and 0.0056, respectively. The fracture toughness of the CNB-FEA models closely matched those of the corresponding test specimens (±3% error). Linear regression yielded a coefficient of determination (R2) of 0.94 (P < 0.05), demonstrating an excellent predictive performance. The CNB-FEA models accurately reflected the actual fracture behaviors of the zirconia ceramics, with the volumetric strain localized at the notch tip.

Conclusions: The volumetric strains of the CNB-FEA models could be determined using the FEA and measured four-point flexural strength data. Thus, CNB-FEA was found to be a valuable method for predicting the fracture toughness of zirconia ceramics.

目的:建立楔形缺口梁(CNB)有限元分析(FEA)模型,研究氧化锆陶瓷的断裂韧性。方法:将3mol %钇稳定的四方氧化锆多晶(3Y-TZP; 3M Oral Care, Seefeld, Germany)的四点抗折强度实验数据(n = 9,已发表)与数值数据(使用逆有限元法计算)相结合,评估CNB-FEA模型的输入材料性能。然后将这些模型(n = 8)与具有相同几何形状的试件(n = 8)的CNB测试数据进行模拟和验证。验证标准包括误差范围、决定系数和线性回归。采用有限元法对变形过程中的体积应变分布进行了分析。结果:3Y-TZP的静态弹性模量为144.5 GPa,断裂应变值为0.0056。CNB-FEA模型的断裂韧性与相应试件的断裂韧性基本吻合(误差为±3%)。线性回归的决定系数(R2)为0.94 (P < 0.05),具有良好的预测效果。CNB-FEA模型准确反映了氧化锆陶瓷的实际断裂行为,体积应变集中在缺口尖端。结论:CNB-FEA模型的体积应变可以通过有限元分析和实测四点抗弯强度数据确定。因此,CNB-FEA是预测氧化锆陶瓷断裂韧性的一种有价值的方法。
{"title":"Fracture toughness evaluation of zirconia ceramics using nonlinear dynamic finite element analysis.","authors":"Okkar Kyaw, Satoshi Yamaguchi, Manabu Kanazawa, Jan De Munck, Pong Pongprueksa, Jef Vleugels, Bart Van Meerbeek, Fei Zhang, Masanao Inokoshi","doi":"10.2186/jpr.JPR_D_25_00242","DOIUrl":"https://doi.org/10.2186/jpr.JPR_D_25_00242","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to establish chevron-notched beam (CNB) finite element analysis (FEA) models to investigate the fracture toughness of zirconia ceramics.</p><p><strong>Methods: </strong>Experimental four-point flexural strength data (n = 9; previously published) for 3 mol% yttria-stabilized tetragonal zirconia polycrystals (3Y-TZP; 3M Oral Care, Seefeld, Germany) were combined with numerical data (calculated using the inverse finite element method) to evaluate the input material properties of the CNB-FEA models. These models (n = 8) were then simulated and validated against the CNB test data of specimens with the same geometries (n = 8). The validation criteria included the margin of error, coefficient of determination, and linear regression. FEA was used to evaluate the volumetric strain distribution during deformation.</p><p><strong>Results: </strong>3Y-TZP has static elastic modulus and fracture strain values of 144.5 GPa and 0.0056, respectively. The fracture toughness of the CNB-FEA models closely matched those of the corresponding test specimens (±3% error). Linear regression yielded a coefficient of determination (R<sup>2</sup>) of 0.94 (P < 0.05), demonstrating an excellent predictive performance. The CNB-FEA models accurately reflected the actual fracture behaviors of the zirconia ceramics, with the volumetric strain localized at the notch tip.</p><p><strong>Conclusions: </strong>The volumetric strains of the CNB-FEA models could be determined using the FEA and measured four-point flexural strength data. Thus, CNB-FEA was found to be a valuable method for predicting the fracture toughness of zirconia ceramics.</p>","PeriodicalId":16887,"journal":{"name":"Journal of prosthodontic research","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145900263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Habitual attentional mastication boosts prefrontal activity during chewing: A randomized trial. 习惯性注意力咀嚼促进咀嚼时前额叶活动:一项随机试验。
IF 3.4 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-05 DOI: 10.2186/jpr.JPR_D_25_00084
Yukina Miyazaki, Yumie Ono, Tatsuya Suzuki, Yoko Hasegawa, Shogo Yoshimura, Ma Therese Sta Maria, Kazuhiro Hori, Kensuke Yamamura, Takahiro Ono

Purpose: Masticatory exercise promotes systemic health and cognitive function. Although acute masticatory stimuli enhance prefrontal cortical activity, the effects of increased habitual chewing on cortical activity remain unclear. This study evaluated the effects of habitual chewing on cortical activity in young adults.

Methods: Forty-one young adults (aged 21-31 years) were randomly assigned to an intervention group, which used a wearable device to increase attentional chewing strokes during meals for 1 month, or a control group that did not use the device. We monitored the cortical activity during gum chewing using functional near-infrared spectroscopy at baseline and immediately after intervention. We recorded the number of chews per rice ball at baseline, immediately after intervention, and at 3 months post-intervention. Changes across different time points in each group were compared using one-sample t-tests with Bonferroni correction.

Results: The intervention group showed a significant increase in the number of chews after the intervention and at the 3-month follow-up, whereas the control group exhibited no changes. Moreover, the intervention group demonstrated significantly higher activity in the dorsolateral prefrontal cortex (DLPFC) and premotor cortex compared with the control group. A voxel-based correlation analysis revealed a positive correlation between increase in chewing strokes and activity in these brain regions in the intervention group (family-wise error-corrected, P < 0.05).

Conclusions: Intentional chewing, enhanced through an attentional intervention, led to increased activation in the DLPFC and premotor cortex during mastication. These results demonstrated the objective neural effects of interventions targeting habitual masticatory behavior.

目的:咀嚼运动促进全身健康和认知功能。虽然急性咀嚼刺激增强前额叶皮层活动,但习惯性咀嚼增加对皮层活动的影响尚不清楚。这项研究评估了习惯咀嚼对年轻人大脑皮层活动的影响。方法:将41名年龄在21-31岁的年轻人随机分为干预组和对照组,干预组使用可穿戴设备在用餐时增加注意力咀嚼卒中1个月,对照组不使用该设备。我们使用功能性近红外光谱在基线和干预后立即监测嚼口香糖时的皮质活动。我们在基线、干预后立即和干预后3个月记录了每个饭团的咀嚼次数。采用Bonferroni校正的单样本t检验比较各组不同时间点的变化。结果:干预组在干预后和随访3个月时咀嚼次数明显增加,而对照组无变化。此外,干预组的背外侧前额叶皮层(DLPFC)和前运动皮层的活动明显高于对照组。基于体素的相关分析显示,干预组咀嚼中风的增加与这些大脑区域的活动呈正相关(家庭误差校正,P < 0.05)。结论:有意识咀嚼,通过注意力干预增强,导致咀嚼过程中DLPFC和运动前皮层的激活增加。这些结果证明了针对习惯性咀嚼行为的干预的客观神经效应。
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引用次数: 0
Direct-indirect technique for ultrathin non-prep resin composite veneers using 3D-printed models and translucent silicone index. 使用3d打印模型和半透明硅胶指数的超薄非制备树脂复合贴面的直接间接技术。
IF 3.4 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-05 DOI: 10.2186/jpr.JPR_D_25_00165
Federico Wirz, María González Agurto, Gerardo Durán Ojeda

Patients: This report presents a minimally invasive, adhesive-friendly approach for the esthetic rehabilitation of multiple anterior teeth using a modified direct-indirect technique with ultrathin composite resin veneers. A 43-year-old woman presented with esthetic concerns and disharmony of the maxillary anterior region. The treatment comprised ultrathin composite resin veneers fabricated using a modified direct-indirect technique, incorporating a fully digital workflow with a smile design and a three-dimensional-printed model used to create a translucent silicone index. Without tooth preparation, the index was filled with composite resin and intraorally positioned to replicate the planned morphology. The veneers were removed, post-cured, and extraorally completed before definitive adhesive cementation.

Discussion: Traditionally, the direct-indirect technique has been limited to single restorations that require enamel reduction and freehand stratification. This report describes a modified approach that enables the fabrication of multiple ultrathin veneers without tooth preparation, thereby preserving the enamel and promoting adhesive longevity. The innovative aspect lies in the integration of a fully digital workflow, ensuring precise replication of the morphology and control of the restoration thickness. Extraoral finishing of proximal contacts and margins before cementation improves clinical efficiency and esthetic predictability.

Conclusions: For patients requiring multiple composite veneers, the modified direct-indirect technique provides a conservative, precise, and predictable solution. It preserves sound tooth structure, optimizes adhesive performance, and enhances efficiency and esthetic outcomes through digital integration.

患者:本报告介绍了一种微创、粘接剂友好的方法,采用改良的直接-间接技术与超薄复合树脂贴面进行多前牙的美学康复。一个43岁的女性提出审美问题和上颌前区不和谐。该处理包括使用改进的直接间接技术制造的超薄复合树脂贴面,结合了带有微笑设计的全数字工作流程和用于创建半透明硅胶指数的三维打印模型。在没有牙齿准备的情况下,用复合树脂填充指数,并在口腔内定位以复制计划的形态。在确定胶粘剂粘合之前,将贴面移除,后固化并口外完成。讨论:传统上,直接-间接技术仅限于单个修复,需要牙釉质还原和徒手分层。本报告描述了一种改进的方法,可以在没有牙齿准备的情况下制造多个超薄贴面,从而保护牙釉质并促进粘合剂的使用寿命。创新之处在于集成了全数字化工作流程,确保了形态的精确复制和修复厚度的控制。在固接前对近端接触点和边缘进行口腔外整理,可提高临床效率和美观的可预测性。结论:对于需要多个复合贴面的患者,改良的直接-间接技术提供了保守、精确和可预测的解决方案。通过数字集成,保持牙齿结构完好,优化粘接性能,提高效率和美观效果。
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引用次数: 0
Effect of resilient denture liners on the maximum compressive force applied to test foods. 弹性义齿衬垫对测试食品最大压缩力的影响。
IF 3.4 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-05 DOI: 10.2186/jpr.JPR_D_25_00109
Atsushi Araki, Yuki Uchiyama, Daisuke Yamaguchi, Hiroshi Usami, Hisato Hotta, Suguru Kimoto

Purpose: This study aimed to determine whether the maximum compressive force exerted on denture base materials by test foods varies depending on the presence and type of resilient denture liners.

Methods: The maximum compressive forces of gummy jelly and peanuts were measured using a texture analyzer equipped with a 500 N load cell, operating at a crosshead speed of 9.78 mm/s. Tests were conducted on rectangular prism-shaped specimens (30 mm × 30 mm × 4 mm) fabricated from various denture base materials. Three commercial silicone-based resilient denture liners-Sofreliner Supersoft (SS), Sofreliner Mediumsoft (MS), and Sofreliner Tough Medium (TM)-and a conventional heat-cured acrylic resin (Urban, UR) were used. Additionally, the Shore A hardness of each material was measured using a hardness tester.

Results: The maximum compressive forces applied to gummy jelly and peanuts on UR specimens were significantly higher than those on TM, MS, and SS specimens. Similarly, the Shore A hardness of UR was higher than that of the other materials. A statistically significant positive correlation was observed between the maximum compressive force of the test foods and the Shore A hardness of the denture base materials.

Conclusions: The maximum compressive force applied to food varied according to the type of denture base materials. In particular, resilient denture liners effectively reduced the force transmitted to the food compared with conventional hard acrylic resin.

目的:本研究旨在确定测试食品对义齿基托材料施加的最大压缩力是否因义齿弹性衬垫的存在和类型而变化。方法:在9.78 mm/s的十字速度下,采用配有500 N称重传感器的质地分析仪测量软糖和花生的最大压缩力。试验采用不同基托材料制作30 mm × 30 mm × 4 mm矩形棱柱样。使用三种商用硅基弹性义齿衬垫-Sofreliner Supersoft (SS), Sofreliner Mediumsoft (MS)和Sofreliner Tough Medium (TM)-以及传统的热固化丙烯酸树脂(Urban, UR)。此外,使用硬度计测量每种材料的邵氏A硬度。结果:软糖果冻和花生在UR上的最大压缩力明显高于TM、MS和SS。同样,UR的邵氏A硬度也高于其他材料。试验食品的最大压缩力与义齿基托材料的Shore A硬度呈显著正相关。结论:根据义齿基托材料的不同,对食物施加的最大压缩力也不同。与传统的硬质丙烯酸树脂相比,弹性义齿衬垫有效地减少了传递给食物的力。
{"title":"Effect of resilient denture liners on the maximum compressive force applied to test foods.","authors":"Atsushi Araki, Yuki Uchiyama, Daisuke Yamaguchi, Hiroshi Usami, Hisato Hotta, Suguru Kimoto","doi":"10.2186/jpr.JPR_D_25_00109","DOIUrl":"https://doi.org/10.2186/jpr.JPR_D_25_00109","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to determine whether the maximum compressive force exerted on denture base materials by test foods varies depending on the presence and type of resilient denture liners.</p><p><strong>Methods: </strong>The maximum compressive forces of gummy jelly and peanuts were measured using a texture analyzer equipped with a 500 N load cell, operating at a crosshead speed of 9.78 mm/s. Tests were conducted on rectangular prism-shaped specimens (30 mm × 30 mm × 4 mm) fabricated from various denture base materials. Three commercial silicone-based resilient denture liners-Sofreliner Supersoft (SS), Sofreliner Mediumsoft (MS), and Sofreliner Tough Medium (TM)-and a conventional heat-cured acrylic resin (Urban, UR) were used. Additionally, the Shore A hardness of each material was measured using a hardness tester.</p><p><strong>Results: </strong>The maximum compressive forces applied to gummy jelly and peanuts on UR specimens were significantly higher than those on TM, MS, and SS specimens. Similarly, the Shore A hardness of UR was higher than that of the other materials. A statistically significant positive correlation was observed between the maximum compressive force of the test foods and the Shore A hardness of the denture base materials.</p><p><strong>Conclusions: </strong>The maximum compressive force applied to food varied according to the type of denture base materials. In particular, resilient denture liners effectively reduced the force transmitted to the food compared with conventional hard acrylic resin.</p>","PeriodicalId":16887,"journal":{"name":"Journal of prosthodontic research","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145899433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of a device for continuous salivary pH measurement at two locations in the oral cavity. 一种在口腔内两个位置连续测量唾液pH值的装置的研制。
IF 3.4 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-02 DOI: 10.2186/jpr.JPR_D_25_00145
Thida Aung, Hiroshi Churei, Kairi Hayashi, Kazuyoshi Tsuchiya, Kazuma Sasaki, Gen Tanabe, Toshiaki Ueno, Kenji Fueki

Purpose: Conventional handheld pH meters have measurement limitations. Therefore, this study aimed to continuously measure the salivary pH at two intraoral locations using a newly developed sensor system.

Methods: In this pilot study, we developed custom-made intraoral mouthguards (MG) with two pH sensors in the anterior region (Channel 1: Ch1) and the buccal side of the maxillary molar (Channel 2: Ch2) to continuously monitor salivary pH at two different locations in the oral cavity.

Results: The coefficient of determination (R2) for all MG sensor measurements was ≥0.99, with a high level of accuracy. Both sensor channels exhibited similar mean pH values for standard solutions, with small and constant variations. However, notable unstable differences in intraoral measurements were observed during rehydration owing to positional differences. Nonetheless, the MG sensors demonstrated excellent reliability with consistently high Intraclass Correlation Coefficients ranging from 0.977 to 0.999.

Conclusions: This pilot study provides valuable insights into salivary pH fluctuations, particularly during exercise, through continuous measurements using a sensor system for the simultaneous acquisition of real-time data from different anatomical sites. These results emphasize the potential of developing an intraoral sensor system that can detect subtle variations in salivary pH.

用途:传统的手持式pH计有测量限制。因此,本研究旨在使用新开发的传感器系统连续测量口腔内两个位置的唾液pH值。方法:在本初步研究中,我们开发了定制的口腔内护齿(MG),在前区(通道1:Ch1)和上颌磨牙颊侧(通道2:Ch2)安装两个pH传感器,连续监测口腔内两个不同位置的唾液pH。结果:MG传感器测定结果的决定系数(R2)均≥0.99,具有较高的准确度。两个传感器通道在标准溶液中表现出相似的平均pH值,具有小而恒定的变化。然而,由于位置差异,在补液期间观察到口腔内测量的显着不稳定差异。尽管如此,MG传感器表现出优异的可靠性,具有一致的高类内相关系数,范围从0.977到0.999。结论:这项初步研究通过使用传感器系统同时获取不同解剖部位的实时数据的连续测量,为唾液pH值波动提供了有价值的见解,特别是在运动期间。这些结果强调了开发一种口腔内传感器系统的潜力,该系统可以检测唾液pH值的细微变化。
{"title":"Development of a device for continuous salivary pH measurement at two locations in the oral cavity.","authors":"Thida Aung, Hiroshi Churei, Kairi Hayashi, Kazuyoshi Tsuchiya, Kazuma Sasaki, Gen Tanabe, Toshiaki Ueno, Kenji Fueki","doi":"10.2186/jpr.JPR_D_25_00145","DOIUrl":"https://doi.org/10.2186/jpr.JPR_D_25_00145","url":null,"abstract":"<p><strong>Purpose: </strong>Conventional handheld pH meters have measurement limitations. Therefore, this study aimed to continuously measure the salivary pH at two intraoral locations using a newly developed sensor system.</p><p><strong>Methods: </strong>In this pilot study, we developed custom-made intraoral mouthguards (MG) with two pH sensors in the anterior region (Channel 1: Ch1) and the buccal side of the maxillary molar (Channel 2: Ch2) to continuously monitor salivary pH at two different locations in the oral cavity.</p><p><strong>Results: </strong>The coefficient of determination (R<sup>2</sup>) for all MG sensor measurements was ≥0.99, with a high level of accuracy. Both sensor channels exhibited similar mean pH values for standard solutions, with small and constant variations. However, notable unstable differences in intraoral measurements were observed during rehydration owing to positional differences. Nonetheless, the MG sensors demonstrated excellent reliability with consistently high Intraclass Correlation Coefficients ranging from 0.977 to 0.999.</p><p><strong>Conclusions: </strong>This pilot study provides valuable insights into salivary pH fluctuations, particularly during exercise, through continuous measurements using a sensor system for the simultaneous acquisition of real-time data from different anatomical sites. These results emphasize the potential of developing an intraoral sensor system that can detect subtle variations in salivary pH.</p>","PeriodicalId":16887,"journal":{"name":"Journal of prosthodontic research","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145900759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of prosthodontic research
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