Pub Date : 2018-10-05DOI: 10.31031/iod.2018.02.000532
Wusa Makena, W. Hamman, A. Buraimoh, N. Dibal
The aim of the study was to evaluate the effect of Balanitoside on hyperglycemia, pancreatic β-cells and oxidative stress in diabetic rats. Eighty diabetic rats were divided into four groups of twenty rats each; group I serve as diabetic control and receive distilled water at 0.5mg/kg, groups II-IV serve as the experimental groups and receive 10mg/kg, 20mg/kg of Balatinoside and 6units/kg of Insulin respectively. Group V serve as the normal control and consist of twenty non-diabetic rats, they were given distilled water at 0.5mg/kg. Five rats from each group were sacrificed on day 8, 15, 22 and 29, the fasting blood glucose levels were monitored on weekly basis. The liver and pancreas were dissected; the liver was homogenized in Phosphate buffer Saline, centrifuged at 5000 x g and used to determine the activities of CAT, SOD and GSH. The pancreas was processed for light microscopic study and stained with H&E and Gomori Aldehyde. The result showed significant reduction in the fasting blood glucose levels of rats treated with Balanitoside and insulin as compared to those of diabetic control (P<0.05), a significant increase in CAT, SOD &GSH levels were observed in rats treated with Balanitoside and insulin as compared with those of diabetic control rats(P<0.05). Regeneration of pancreatic β-cells was observed in rats treated with Balanitoside and insulin. In conclusion, Balanitoside decrease blood glucose levels and oxidative stress in diabetic rats and cause the regeneration of pancreatic β-cells.
本研究旨在探讨白头草苷对糖尿病大鼠高血糖、胰腺β细胞及氧化应激的影响。将80只糖尿病大鼠分为4组，每组20只;I组为糖尿病对照组，给予0.5mg/kg蒸馏水;II-IV组为实验组，分别给予Balatinoside 10mg/kg、20mg/kg、6units/kg胰岛素。V组为正常对照，20只非糖尿病大鼠，给予0.5mg/kg蒸馏水。每组各取5只大鼠于第8、15、22、29天处死，每周监测一次空腹血糖水平。切除肝脏、胰腺;肝脏在磷酸盐缓冲盐水中匀浆，5000 x g离心，测定CAT、SOD和GSH的活性。胰腺行光镜观察，H&E和Gomori醛染色。结果表明，与糖尿病对照组相比，balanito苷和胰岛素组大鼠的空腹血糖水平显著降低(P<0.05)， balanito苷和胰岛素组大鼠的CAT、SOD和gsh水平显著升高(P<0.05)。balanito苷和胰岛素处理大鼠胰腺β细胞再生。综上所述，巴兰尼托苷能降低糖尿病大鼠的血糖水平和氧化应激，促进胰腺β细胞的再生。
{"title":"Role of Balanitoside on Hyperglycemia and Oxidative Stress in Diabetic Rats","authors":"Wusa Makena, W. Hamman, A. Buraimoh, N. Dibal","doi":"10.31031/iod.2018.02.000532","DOIUrl":"https://doi.org/10.31031/iod.2018.02.000532","url":null,"abstract":"The aim of the study was to evaluate the effect of Balanitoside on hyperglycemia, pancreatic β-cells and oxidative stress in diabetic rats. Eighty diabetic rats were divided into four groups of twenty rats each; group I serve as diabetic control and receive distilled water at 0.5mg/kg, groups II-IV serve as the experimental groups and receive 10mg/kg, 20mg/kg of Balatinoside and 6units/kg of Insulin respectively. Group V serve as the normal control and consist of twenty non-diabetic rats, they were given distilled water at 0.5mg/kg. Five rats from each group were sacrificed on day 8, 15, 22 and 29, the fasting blood glucose levels were monitored on weekly basis. The liver and pancreas were dissected; the liver was homogenized in Phosphate buffer Saline, centrifuged at 5000 x g and used to determine the activities of CAT, SOD and GSH. The pancreas was processed for light microscopic study and stained with H&E and Gomori Aldehyde. The result showed significant reduction in the fasting blood glucose levels of rats treated with Balanitoside and insulin as compared to those of diabetic control (P<0.05), a significant increase in CAT, SOD &GSH levels were observed in rats treated with Balanitoside and insulin as compared with those of diabetic control rats(P<0.05). Regeneration of pancreatic β-cells was observed in rats treated with Balanitoside and insulin. In conclusion, Balanitoside decrease blood glucose levels and oxidative stress in diabetic rats and cause the regeneration of pancreatic β-cells.","PeriodicalId":170669,"journal":{"name":"Interventions in Obesity & Diabetes","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122746377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-10-03DOI: 10.31031/RMES.2018.06.000647
Vinod Nikhra
Overnutrition and adiposity: Overnutrition contributes to chronic energy surplus leading to adiposity, insulin resistance (IR), metabolic syndrome (MetS) and obesity with its fallouts including increased oxidative stress, altered glucose, fat and protein metabolism, and altered skeletal muscle mitochondrial function. Redox balance and thioredoxin system: The cellular redox balance is regulated by activity of several antioxidant systems including thioredoxin (TXN) normal fasting glycaemia and TXNIP being a tumour suppressor, its loss is associated with increased incidence of cancer.
{"title":"Revisiting Caloric Restriction as Therapeutic Strategy for Metabolic Syndrome, T2DM and Obesity","authors":"Vinod Nikhra","doi":"10.31031/RMES.2018.06.000647","DOIUrl":"https://doi.org/10.31031/RMES.2018.06.000647","url":null,"abstract":"Overnutrition and adiposity: Overnutrition contributes to chronic energy surplus leading to adiposity, insulin resistance (IR), metabolic syndrome (MetS) and obesity with its fallouts including increased oxidative stress, altered glucose, fat and protein metabolism, and altered skeletal muscle mitochondrial function. Redox balance and thioredoxin system: The cellular redox balance is regulated by activity of several antioxidant systems including thioredoxin (TXN) normal fasting glycaemia and TXNIP being a tumour suppressor, its loss is associated with increased incidence of cancer.","PeriodicalId":170669,"journal":{"name":"Interventions in Obesity & Diabetes","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121637024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-14DOI: 10.31031/iod.2018.02.000530
M. Sheth
Diabetes is a complex and chronic illness requiring persistent medical care. The prevalence of diabetes is increasing all over the world at an alarming rate [1] and is a growing public health problem in both developed and developing countries. It can be controlled but not cured. Insufficient insulin, insulin resistance or insulin insensitivity leads to type 2 diabetes mellitus. Due to this, body cells are not able to utilize the glucose and ultimately lead to hyperglycaemia. Long term uncontrolled diabetes mellitus affect the metabolism of the body. Uncontrolled diabetes mellitus leads to raised serum triglycerides, very low density lipoproteins (VLDL) and cholesterol [2]. On the other hand, low HDL was seen to be associated with Diabetes [3].
{"title":"Raised Hs-Crp Levels, Low Vitamin D Levels and High Diastolic Blood Pressure-Emerging as Strong Predictors of Type 2 Diabetes Mellitus Population","authors":"M. Sheth","doi":"10.31031/iod.2018.02.000530","DOIUrl":"https://doi.org/10.31031/iod.2018.02.000530","url":null,"abstract":"Diabetes is a complex and chronic illness requiring persistent medical care. The prevalence of diabetes is increasing all over the world at an alarming rate [1] and is a growing public health problem in both developed and developing countries. It can be controlled but not cured. Insufficient insulin, insulin resistance or insulin insensitivity leads to type 2 diabetes mellitus. Due to this, body cells are not able to utilize the glucose and ultimately lead to hyperglycaemia. Long term uncontrolled diabetes mellitus affect the metabolism of the body. Uncontrolled diabetes mellitus leads to raised serum triglycerides, very low density lipoproteins (VLDL) and cholesterol [2]. On the other hand, low HDL was seen to be associated with Diabetes [3].","PeriodicalId":170669,"journal":{"name":"Interventions in Obesity & Diabetes","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127396927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-08-23DOI: 10.31031/iod.2018.02.000527
Ambarkova Vesna
Dental plaque bacteria along with its products such as lipopolysaccharides (LPS) cause the destruction of the periodontal tissue directly and indirectly by activating the host’s defensive cells of the immune system, which in turn produce and release mediators that stimulate the effects of connective tissue expansion. Microbial plaque components have the capacity to induce initial inflammation and infiltration of inflammatory cells, including lymphocytes, macrophages, and polymorph nuclear leucocytes (PMNl). Microbial components, in particular LPS, activate macrophages to synthesize and secrete various proinflammatory molecules, including cytokines-IL-1 and tumor necrosis factor-alpha (TNF-alpha); prostaglandins, especially prostaglandin E2 (PGE2) and hydrolytic enzymes. The bacteria activate T lymphocytes for the production of IL-1 and lymphotoxin (LT), a molecule with similar properties of TNF-alpha. These cytokines manifest potent proinflammatory and catabolic activities and play a key role in the formation of periodontal pockets through collagenolytic enzymes such as matrix metalloproteinases (MMP). These latent collagenolytic enzymes are activated by reactive oxygen species in the inflammatory environment, leading to increased levels of interstitial collagenase in the inflamed gingiva, which deepens the gingival sulcus, creating a parodontal pocket [1]. A periodontal pocket with a depth of 4 to 12mm is a port of 107 to 109 bacterial cells.
牙菌斑细菌及其产物，如脂多糖(LPS)，通过激活宿主免疫系统的防御细胞，直接或间接地破坏牙周组织，进而产生并释放刺激结缔组织扩张的介质。微生物斑块成分具有诱导初始炎症和炎症细胞浸润的能力，包括淋巴细胞、巨噬细胞和多态核白细胞(PMNl)。微生物成分，特别是LPS，激活巨噬细胞合成和分泌各种促炎分子，包括细胞因子- il -1和肿瘤坏死因子- α (tnf - α);前列腺素，特别是前列腺素E2 (PGE2)和水解酶。细菌激活T淋巴细胞产生IL-1和淋巴毒素(LT)，这是一种与tnf - α性质相似的分子。这些细胞因子表现出强大的促炎和分解代谢活性，并通过基质金属蛋白酶(MMP)等胶原溶解酶在牙周袋的形成中发挥关键作用。这些潜伏的胶原溶解酶在炎症环境中被活性氧激活，导致炎症牙龈间质胶原酶水平升高，使牙龈沟加深，形成牙周袋[1]。深度为4至12毫米的牙周袋是107至109个细菌细胞的端口。
{"title":"Etiologic Factors of The Periodontal Disease Pathogenesis","authors":"Ambarkova Vesna","doi":"10.31031/iod.2018.02.000527","DOIUrl":"https://doi.org/10.31031/iod.2018.02.000527","url":null,"abstract":"Dental plaque bacteria along with its products such as lipopolysaccharides (LPS) cause the destruction of the periodontal tissue directly and indirectly by activating the host’s defensive cells of the immune system, which in turn produce and release mediators that stimulate the effects of connective tissue expansion. Microbial plaque components have the capacity to induce initial inflammation and infiltration of inflammatory cells, including lymphocytes, macrophages, and polymorph nuclear leucocytes (PMNl). Microbial components, in particular LPS, activate macrophages to synthesize and secrete various proinflammatory molecules, including cytokines-IL-1 and tumor necrosis factor-alpha (TNF-alpha); prostaglandins, especially prostaglandin E2 (PGE2) and hydrolytic enzymes. The bacteria activate T lymphocytes for the production of IL-1 and lymphotoxin (LT), a molecule with similar properties of TNF-alpha. These cytokines manifest potent proinflammatory and catabolic activities and play a key role in the formation of periodontal pockets through collagenolytic enzymes such as matrix metalloproteinases (MMP). These latent collagenolytic enzymes are activated by reactive oxygen species in the inflammatory environment, leading to increased levels of interstitial collagenase in the inflamed gingiva, which deepens the gingival sulcus, creating a parodontal pocket [1]. A periodontal pocket with a depth of 4 to 12mm is a port of 107 to 109 bacterial cells.","PeriodicalId":170669,"journal":{"name":"Interventions in Obesity & Diabetes","volume":"40 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132432795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-08-22DOI: 10.31031/iod.2018.02.000528
G. Rao
Excess weight, body-mass index (BMI), and obesity, have become global epidemics. According to the experts, if post-2000 trends continue, the probability of meeting the global obesity target is virtually zero [1]. Several recent studies have assessed the national, regional and global, prevalence of excess weight and obesity [2-10]. Influence of modifiable risk factors, such as blood pressure, serum cholesterol, fasting glucose, and body mass index on cardiovascular disease (CVD) is well established. Each metabolic risk factor is robustly related to the progress of CVD. Global estimates indicate, considerable potential for CVD reduction, with population-wide lowering of BMI [2]. A bilateral study, between the researchers at the Madras Diabetes Research Foundation (MDRF), and the staff at the University of Minnesota, found that compared to the US, the waist-weight ratio was significantly higher, in men and women from India [3]. These results support the hypothesis, that South Asians are particularly predisposed toward central adiposity. There is a great need to assess the role of BMI, waist circumference, and waist-to-hip ratios (WHR), to see if these parameters, singly or in combination, improve CVD risk prediction, so that ethnic-specific or region-specific guidelines, could be developed for prevention strategies [5]. Chinese researchers have reported, significant association with increased WHR, with a stronger association among women [11]. Global epidemics of metabolic diseases, if not controlled soon, could cause economic disaster in many countries. A recent (2018), National Health Service (NHS), UK model indicates, that NHS Health Check programme is contributing significantly, to the improvements in health and reducing healthcare inequalities. They predict that feasible changes in the organization of the programme, could result in more than 3-fold increase in health benefits [12]. In an earlier article in this journal, we articulated the management of excess weight and obesity [13]. In this article, we will discuss three possible interventions, which may reduce or reverse the metabolic risks, associated with excess weight and obesity.
{"title":"Obesity Epidemic: A Global Perspective","authors":"G. Rao","doi":"10.31031/iod.2018.02.000528","DOIUrl":"https://doi.org/10.31031/iod.2018.02.000528","url":null,"abstract":"Excess weight, body-mass index (BMI), and obesity, have become global epidemics. According to the experts, if post-2000 trends continue, the probability of meeting the global obesity target is virtually zero [1]. Several recent studies have assessed the national, regional and global, prevalence of excess weight and obesity [2-10]. Influence of modifiable risk factors, such as blood pressure, serum cholesterol, fasting glucose, and body mass index on cardiovascular disease (CVD) is well established. Each metabolic risk factor is robustly related to the progress of CVD. Global estimates indicate, considerable potential for CVD reduction, with population-wide lowering of BMI [2]. A bilateral study, between the researchers at the Madras Diabetes Research Foundation (MDRF), and the staff at the University of Minnesota, found that compared to the US, the waist-weight ratio was significantly higher, in men and women from India [3]. These results support the hypothesis, that South Asians are particularly predisposed toward central adiposity. There is a great need to assess the role of BMI, waist circumference, and waist-to-hip ratios (WHR), to see if these parameters, singly or in combination, improve CVD risk prediction, so that ethnic-specific or region-specific guidelines, could be developed for prevention strategies [5]. Chinese researchers have reported, significant association with increased WHR, with a stronger association among women [11]. Global epidemics of metabolic diseases, if not controlled soon, could cause economic disaster in many countries. A recent (2018), National Health Service (NHS), UK model indicates, that NHS Health Check programme is contributing significantly, to the improvements in health and reducing healthcare inequalities. They predict that feasible changes in the organization of the programme, could result in more than 3-fold increase in health benefits [12]. In an earlier article in this journal, we articulated the management of excess weight and obesity [13]. In this article, we will discuss three possible interventions, which may reduce or reverse the metabolic risks, associated with excess weight and obesity.","PeriodicalId":170669,"journal":{"name":"Interventions in Obesity & Diabetes","volume":"277 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121262778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-08-16DOI: 10.31031/iod.2018.02.000526
Yimer Mihretie
Adequate nutritional status of women is important for good health and increased work capacity of women as well as for the health of their children. However under nutrition and poor health adversely affect the well-being of millions of people in the developing world. More than 3.5 million women and children less than five aged in developing countries died each year due to the underlying cause of under nutrition. The purpose of this article is to review the factors affecting the nutritional status of women in Ethiopia. Women are mostly venerable to malnutrion because of the intake of unbalanced foods due to low economic status, low education background, marital status and age. Women of the reproductive age are amongst the most vulnerable to malnutrition. Additionally place of women residence was one factor contributing to the nutritional variation between rural and urban women. There has been a variation between married and unmarried women in their nutritional status. The unmarried and divorced women had relatively high malnutrition problem than married one. However, this argument in the economic status of women is different. Whether the women have got married or unmarried, the economic status could be the cause of malnutrition if they are coming from low economic family. Therefore in order to have the women better understanding about nutritional status, they should be encouraged to attend nutrition education.
{"title":"Review on Factors Affecting the Nutritional Status of Women in Ethiopia","authors":"Yimer Mihretie","doi":"10.31031/iod.2018.02.000526","DOIUrl":"https://doi.org/10.31031/iod.2018.02.000526","url":null,"abstract":"Adequate nutritional status of women is important for good health and increased work capacity of women as well as for the health of their children. However under nutrition and poor health adversely affect the well-being of millions of people in the developing world. More than 3.5 million women and children less than five aged in developing countries died each year due to the underlying cause of under nutrition. The purpose of this article is to review the factors affecting the nutritional status of women in Ethiopia. Women are mostly venerable to malnutrion because of the intake of unbalanced foods due to low economic status, low education background, marital status and age. Women of the reproductive age are amongst the most vulnerable to malnutrition. Additionally place of women residence was one factor contributing to the nutritional variation between rural and urban women. There has been a variation between married and unmarried women in their nutritional status. The unmarried and divorced women had relatively high malnutrition problem than married one. However, this argument in the economic status of women is different. Whether the women have got married or unmarried, the economic status could be the cause of malnutrition if they are coming from low economic family. Therefore in order to have the women better understanding about nutritional status, they should be encouraged to attend nutrition education.","PeriodicalId":170669,"journal":{"name":"Interventions in Obesity & Diabetes","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125233217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-07-23DOI: 10.31031/iod.2018.01.000524
Joy A. Dugan, Pa-C
Diabetes mellitus is considered a global epidemic, with financial impacts beyond the cost of treatment. Multiple treatment options are available; however, many healthcare providers lack knowledge or face perceived barriers to prescription. While the American Diabetes Association publishes yearly guideline updates for the management and care of diabetes, many health care providers are unfamiliar with these guidelines. These guidelines recommend insulin and other inject able therapies early in the disease progression, yet the DAWN study demonstrated that physicians delay the initiation of insulin therapy. This paper will review the knowledge gaps, health care provider barriers, and perceptions of inject able therapies. From this review, more knowledge is needed by prescribers in the initiation and management of injectable therapies to help patients successfully reach glycemic targets.
{"title":"Healthcare Perceptions of Injectable Therapies for Diabetes Mellitus Type 2","authors":"Joy A. Dugan, Pa-C","doi":"10.31031/iod.2018.01.000524","DOIUrl":"https://doi.org/10.31031/iod.2018.01.000524","url":null,"abstract":"Diabetes mellitus is considered a global epidemic, with financial impacts beyond the cost of treatment. Multiple treatment options are available; however, many healthcare providers lack knowledge or face perceived barriers to prescription. While the American Diabetes Association publishes yearly guideline updates for the management and care of diabetes, many health care providers are unfamiliar with these guidelines. These guidelines recommend insulin and other inject able therapies early in the disease progression, yet the DAWN study demonstrated that physicians delay the initiation of insulin therapy. This paper will review the knowledge gaps, health care provider barriers, and perceptions of inject able therapies. From this review, more knowledge is needed by prescribers in the initiation and management of injectable therapies to help patients successfully reach glycemic targets.","PeriodicalId":170669,"journal":{"name":"Interventions in Obesity & Diabetes","volume":"7 3-4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133170602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-07-19DOI: 10.31031/iod.2018.01.000523
G. Rao
Non-communicable diseases (NCDs), especially, hypertension, excess weight, obesity, metabolic syndrome, type-2 diabetes, and vascular diseases, have increased rapidly in the last two decades and have reached an epidemic status worldwide. Some experts have compared this increase in the incidence of these diseases as “tsunamis”. Tsunamis’ are seasonal and unpredictable whereas, these diseases are predictable and not seasonal. So, what are we going to do about this situation? Are we going to sit and wait for some miracle to happen? What are the member nations of the United Nations, World Health Organization, NCD Task Force going to do about this, besides writing and publishing scary reports of future economic and healthcare disasters? In this overview, we would like to discuss briefly the salient findings on this topic, initiate a healthy dialogue, request suggestions, positive comments, and offer few suggestions. Intervention in Obesity & Diabetes C CRIMSON PUBLISHERS Wings to the Research
{"title":"Management of Excess Weight and Obesity: A Global Perspective","authors":"G. Rao","doi":"10.31031/iod.2018.01.000523","DOIUrl":"https://doi.org/10.31031/iod.2018.01.000523","url":null,"abstract":"Non-communicable diseases (NCDs), especially, hypertension, excess weight, obesity, metabolic syndrome, type-2 diabetes, and vascular diseases, have increased rapidly in the last two decades and have reached an epidemic status worldwide. Some experts have compared this increase in the incidence of these diseases as “tsunamis”. Tsunamis’ are seasonal and unpredictable whereas, these diseases are predictable and not seasonal. So, what are we going to do about this situation? Are we going to sit and wait for some miracle to happen? What are the member nations of the United Nations, World Health Organization, NCD Task Force going to do about this, besides writing and publishing scary reports of future economic and healthcare disasters? In this overview, we would like to discuss briefly the salient findings on this topic, initiate a healthy dialogue, request suggestions, positive comments, and offer few suggestions. Intervention in Obesity & Diabetes C CRIMSON PUBLISHERS Wings to the Research","PeriodicalId":170669,"journal":{"name":"Interventions in Obesity & Diabetes","volume":"172 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114491700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-26DOI: 10.31031/iod.2018.01.000522
Sidhra Syed Zameer Ahmed
{"title":"In Vitro Radical Scavenging Activity and Modulating Effect of Annona Cherimola on Complications Associated With Diabetes in Experimental Diabetic Rats-An Approach to Evaluate Asymmetrical Temperature Distribution Analysis Using Thermography","authors":"Sidhra Syed Zameer Ahmed","doi":"10.31031/iod.2018.01.000522","DOIUrl":"https://doi.org/10.31031/iod.2018.01.000522","url":null,"abstract":"","PeriodicalId":170669,"journal":{"name":"Interventions in Obesity & Diabetes","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121321848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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