Journal of tissue viability最新文献

{"title":"Effectiveness of topically applied MEBO in healing of traumatic oral ulcer: Randomized controlled trial","authors":"Amany Ahmed AlAraby ,&nbsp;Nadia Fathy Hassabou ,&nbsp;Wessam Ibrahim Shehab Eldin","doi":"10.1016/j.jtv.2025.100877","DOIUrl":"10.1016/j.jtv.2025.100877","url":null,"abstract":"<div><h3>Background</h3><div>MEBO is an analgesic and antibacterial natural agent. Sesame oil extract plays a positive effect in wound healing that may be attributed to its ability to scavenge free radicals and antioxidant properties.</div></div><div><h3>Material and methods</h3><div>In this study, MEBO was topically applied to the site of a traumatic oral ulcer to examine its therapeutic effect on pain relief and wound healing. Patients were randomly assigned into two equal groups: group I (MEBO), group II (control), (n = 15 patients each). Pain was recorded by using the Visual Analogue Scale (VAS), wound size was measured at days 2, 5, and 10. Cytological analysis was also performed using the superficial epithelial cell and keratinization indices.</div></div><div><h3>Results</h3><div>There was a statistically significant difference in VAS scores and wound size between MEBO group and control group (p ≤ 0.001). Cytological results of MEBO group showed a highly significant improvement (p ≤ 0.00001) in re-epithelization and keratinization indices over time.</div></div><div><h3>Conclusion</h3><div>Our results showed that the application of MEBO on traumatic ulcer sites has a significant improvement in wound healing and rapid enhancing effect on the re-epithelialization rate.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100877"},"PeriodicalIF":2.4,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143527362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Twenty-one year trends in pressure injury in a Western Australian hospital","authors":"Linda L. Coventry ,&nbsp;Istvan Kabdebo ,&nbsp;Nicole Walsh ,&nbsp;Joelle Winderbaum ,&nbsp;Mark Jenkins ,&nbsp;Prachi Kaistha ,&nbsp;Diane E. Twigg ,&nbsp;Shirley Jansen ,&nbsp;Dimitri Beeckman","doi":"10.1016/j.jtv.2025.100878","DOIUrl":"10.1016/j.jtv.2025.100878","url":null,"abstract":"","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100878"},"PeriodicalIF":2.4,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143520341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence and risk factors of medical adhesive-related skin injuries in outpatients with peripherally inserted central catheters","authors":"Qi Xia ,&nbsp;Xin Chen ,&nbsp;QingHua Ma ,&nbsp;DingDing Zhang","doi":"10.1016/j.jtv.2025.100875","DOIUrl":"10.1016/j.jtv.2025.100875","url":null,"abstract":"<div><h3>Aims</h3><div>Skin exposed to the adhesives to protect catheters is prone to Medical Adhesive-Related Skin Injuries (MARSI). Occurrence of these injuries and the risk factors have not been estimated previously in outpatients with peripherally inserted central catheters. The primary aim of this study was to delineate the characteristics of MARSI and quantify 3 types of incidence rates of MARSI among outpatients with PICC placements.</div></div><div><h3>Methods</h3><div>The study sample included 299 outpatients with PICC placements from October to December 2020. The data were collected at the Sichuan Academy of Medical Sciences&amp;Sichuan Provincial People's Hospital in Chengdu, China.A three-month cross-sectional survey was conducted at the PICC center of a tertiary general hospital in Western China to analyze the occurrence of MARSI at the catheterization site and related factors. Professional nurses observed and assessed skin conditions during catheter maintenance and collected patient data that could be associated with MARSI occurrence. The relationship between independent variables and MARSI was statistically analyzed using multivariate analysis.</div></div><div><h3>Results</h3><div>Among outpatients with peripherally inserted central catheters,the incidence rate of MARSI was 14.7 %. Statistical analysis revealed that maintenance personnel (χ² = 8.683, P = 0.003), MARSI history (χ² = 4.332, P = 0.037), external fixation devices (χ² = 4.227, P = 0.04) were significantly associated with the occurrence of MARSI. Moreover, patients over the age of 50 (χ² = 4.183, P = 0.041) and the use of transparent dressing (χ² = 6.782, P = 0.009) were found to be associated with tension injuries. A multivariate analysis showed that the use of external fixation devices (OR, 2.987; 95 % CI, 1.044 to 8.547; P = 0.041) was an independent risk factor for MARSI.</div></div><div><h3>Conclusions</h3><div>Patients with PICC in the outpatient department are at a high risk of developing MARSI. To prevent and control MARSI,it is essential to enhance the professional skills of maintenance staff and to pay special attention to patients with a history of MARSI and those over the age of 50. Additionally,the use of external fixation devices and transparent dressings should also be considered.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100875"},"PeriodicalIF":2.4,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143520342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nurses' knowledge of skin tears: A cross-sectional survey study across four hospitals in São Paulo, Brazil","authors":"Cinthia Viana Bandeira da Silva ,&nbsp;Dimitri Beeckman ,&nbsp;Vera Lucia Conceição de Gouveia Santos","doi":"10.1016/j.jtv.2025.100874","DOIUrl":"10.1016/j.jtv.2025.100874","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to assess and analyze nurses' knowledge regarding Skin Tears (STs).</div></div><div><h3>Methods</h3><div>An observational, exploratory, and cross-sectional study was conducted across four hospitals in São Paulo, Brazil, encompassing diverse settings: two public hospitals (one affiliated with a university and the other serving state public service professionals) and two private hospitals (one specializing in highly complex cases and the other a general hospital). Data collection involved two instruments: one for sample characterization and another, the OASES instrument, which was translated and content-validated for use in Brazilian Portuguese, to assess nurses' knowledge on STs. Data were analyzed using measures of central tendency and variability.</div></div><div><h3>Results</h3><div>The study included 179 nurses, with an average score of 10.83 (SD = 3.32). Higher knowledge levels were observed in nurses who had received training on STs (p = 0.003) and those who participated in scientific activities (p &lt; 0.001).</div></div><div><h3>Conclusions</h3><div>Nurses across the four hospitals in São Paulo demonstrated a level of knowledge about STs that was slightly higher compared to international benchmarks in similar studies.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100874"},"PeriodicalIF":2.4,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143520340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of decellularized tissues in ear regeneration","authors":"Manouchehr Avatef Fazeli ,&nbsp;Masoumeh Amiri ,&nbsp;Gelavizh Rostaminasab ,&nbsp;Vahid Akbaripour ,&nbsp;Abdolhamid Mikaeili ,&nbsp;Mohammad Othman ,&nbsp;Leila Rezakhani","doi":"10.1016/j.jtv.2025.100870","DOIUrl":"10.1016/j.jtv.2025.100870","url":null,"abstract":"<div><div>More than 5 % of people worldwide suffer from hearing disorders. Ototoxic drugs, aging, exposure to loud sounds, rupture, subperichondrial hematoma, perichondritis, burns and frostbite and infections are the main causes of hearing loss, some of which can destroy the cartilage and lead to deformation. On the other hand, disorders of the external ear are diverse and can range from dangerous neoplasms to defects that are not acceptable from a cosmetic standpoint. These issues include injuries, blockages, dermatoses, and infections, and any or all of them may be bothersome to the busy doctor. Using an implant or hearing aid is one of the treatment strategies for deafness. However, these medical devices are not useful for every eligible patient. With the right therapy, many of these issues are not life-threatening and can be treated with confidence in a positive outcome. As medical research and treatment have advanced dramatically in the past ten years, tissue engineering (TE) has emerged as a promising method to regenerate damaged tissue, raising the prospect of a permanent cure for deafness. Decellularization is now seen as a promising development for regenerative medicine, and an increasing number of applications are being found for acellular matrices. Studies on decellularization show that natural scaffolds made from decellularized tissues can serve as a suitable platform while preserving the main components, and the preparation of such scaffolds will be an important part of future bioscience research. It can have wide applications in regenerative medicine and TE. This review intends to give an overview of the status of research and alternative scaffolds in inner and outer ear regenerative medicine from both a preclinical and clinical perspective for ear disorders in order to show how ongoing TE research has the potential to advance and enhance novel disease treatments.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100870"},"PeriodicalIF":2.4,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143436471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accelerative effect of Carbazole nanocubosomes on the healing of methicillin-resistant Staphylococcus aureus-infected full-thickness wounds","authors":"Saba Samari ,&nbsp;Mohammad Reza Farahpour ,&nbsp;Zohreh Ghazi Tabatabaei","doi":"10.1016/j.jtv.2025.100869","DOIUrl":"10.1016/j.jtv.2025.100869","url":null,"abstract":"<div><h3>Background</h3><div>Bacterial infections remain a major challenge in the treatment of infected wounds due to their resistance. Novel agents are urgently needed for effective treatment. This study aimed to evaluate the effects of carbazole nanocubosomes on the healing of methicillin-resistant <em>Staphylococcus aureus</em> (MRSA)-infected full-thickness wounds.</div></div><div><h3>Materials and methods</h3><div>Carbazole (Carbz) and cubosome/carbazole (Cubo/Carbz) structures were synthesized, and their physicochemical properties, toxicity, and in vitro antibacterial activities were assessed. The wound healing activity was evaluated by analyzing pathological parameters, including edema, immune cell infiltration, new vessel formation, fibroblast infiltration, and epithelial thickness. Additionally, the expression levels of TNF-α, Bcl-2, P-53, mTOR, cyclin D1, TGF-β, VEGF, and Col1A were measured to assess the effects of cubosomes on the wound healing process. The results confirmed the successful synthesis of cubosomes, along with the safety, antibacterial activity, and sustained release of Carbz.</div></div><div><h3>Results</h3><div>The administration of Carbz, particularly the Cubo/Carbz formulations, significantly accelerated the wound healing process by reducing bacterial counts, edema, immune cell infiltration, and the expression of Bcl-2 and TNF-α. Simultaneously, fibroblast infiltration, epithelial thickness, and the expression of P-53, mTOR, Col1A, cyclin D1, TGF-β, and VEGF were increased.</div></div><div><h3>Conclusion</h3><div>In conclusion, Cubo/Carbz accelerates the wound healing process by promoting apoptosis, reducing inflammation, and enhancing the expression of proliferative genes.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100869"},"PeriodicalIF":2.4,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143419475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a graded management program for patients with diabetic foot ulcers based on the triangle model: A Delphi study","authors":"Xiaohong Sun,&nbsp;Jing Yuan,&nbsp;Minli Xu,&nbsp;Wen Lu,&nbsp;Datong Den,&nbsp;Xiaotong Zhao,&nbsp;Juan Gong","doi":"10.1016/j.jtv.2025.100868","DOIUrl":"10.1016/j.jtv.2025.100868","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Objective&lt;/h3&gt;&lt;div&gt;To develop a structured nursing intervention program for individuals with diabetic foot ulcers (DFU), utilizing the Triangle Chronic Disease Stratified and Graded Management Model as a core framework.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Design&lt;/h3&gt;&lt;div&gt;A Delphi study.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Settings&lt;/h3&gt;&lt;div&gt;The semi-structured interview and preliminary formulation were carried out within the endocrinology department of a tertiary hospital located in Anhui Province, China.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Participants&lt;/h3&gt;&lt;div&gt;Ten endocrinologists, two specialists in wound repair, one expert in chronic illness management, one health education specialist, and one sports rehabilitation expert from China's endocrinology and wound repair surgical departments.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;Potential elements for the draft were selected via literature review, and the specific content, needs, challenges, current circumstances, and barriers associated with the stratified management of patients with diabetic foot ulcers (DFU) were elucidated through interviews with 16 patients and 15 medical professionals. Following four rounds of online discussions among the research team, a correspondence questionnaire for Delphi experts was meticulously crafted using the Triangle Chronic Disease Hierarchical Management Model. The questionnaire was disseminated through email to 15 domestic experts in the field from October 2023 to March 2024. The expert positive coefficient, authority coefficients, and Kendall's concordance coefficients were employed to evaluate the dependability of the graded management program. The consultation ended when expert viewpoints aligned.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;A total of twenty-two literature sources were integrated, and interviews were conducted with sixteen DFU patients and fifteen medical personnel before the questionnaire was developed. The program experienced two iterations of collective evaluation and feedback. The response rate for both rounds of expert consultation reached an impressive 100 %. The coefficients of expert authority were recorded at 0.80 and 0.81, respectively. The concordance coefficients calculated by Kendall for the significance and feasibility of the items across the two consultation rounds were 0.271 and 0.183 (P &lt; 0.001), and 0.283 and 0.237 (P &lt; 0.001), respectively. The management program comprises 80 items, systematically classified into three distinct components: i) Organizational structure, ii) Stratification standards, and iii) Grading measures. The composition comprised three principal entries, nine subordinate entries, and sixty-eight ancillary entries.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;div&gt;Our findings suggest that the graded management program for patients with DFU demonstrates a significant degree of scientific rigor, reliability, practicality, and feasibility. This approach tackles the individualized care requirements of DFU, potentially offering a systematic, evidence-based, ","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100868"},"PeriodicalIF":2.4,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143395663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The evaluation of an intelligent closed loop dynamic sitting system to promote good posture, pressure relief and tissue perfusion","authors":"Silvia Caggiari ,&nbsp;Rosemary Hallgarth ,&nbsp;Krishna Mooroogen ,&nbsp;Sheana Yu ,&nbsp;Peter R. Worsley","doi":"10.1016/j.jtv.2025.100867","DOIUrl":"10.1016/j.jtv.2025.100867","url":null,"abstract":"<div><h3>Aim</h3><div>When sitting, buttocks and thighs are subjected to higher pressures, which if sustained can be a risk factor in pressure ulcer development. This study aimed at evaluating the biomechanical and physiological performance of a dynamic sitting system incorporating pressure sensitive air cells technology to provide pressure relief and maintaining skin health.</div></div><div><h3>Materials and methods</h3><div>Thirteen participants were recruited and asked to adopt five static postures in a random order, each held for 10 min. Measurements at the chair-participant interface included interface pressure, internal pressure of the chair air cells, transcutaneous tissue gas tensions at the ischial tuberosities, and accelerometer data collected from the sternum. Area under the Receiver Operating Characteristic curve was used to evaluate sensitivity and specificity of all parameters in detecting postural change events, examining the 1st spatial derivative.</div></div><div><h3>Results</h3><div>Data revealed a high inter-subject variability, with interface pressure e.g. peak pressure gradient and contact area data showing statistically significant difference between postures. This was reflected in the physiological response with some individuals exhibiting low O₂ levels and associated high CO₂ (&gt;25 % from baseline). Area under the curve values revealed interface pressure parameters and actimetry data accurate in detecting postural changes events (≥0.6).</div></div><div><h3>Conclusion</h3><div>The dynamic seating support depended on posture, although there remained some significant differences in interface pressure values and local tissue physiology. Further research is required to assess the impact of these sitting conditions in vulnerable individuals.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100867"},"PeriodicalIF":2.4,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143419479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, attitude and practice regarding anterior cruciate ligament injuries among the youth","authors":"Ling Yin,&nbsp;Juan Deng,&nbsp;Qin Ju,&nbsp;Xiaoqin Fu","doi":"10.1016/j.jtv.2025.100866","DOIUrl":"10.1016/j.jtv.2025.100866","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to explore the knowledge, attitude, and practice (KAP) concerning anterior cruciate ligament (ACL) injuries among the youth.</div></div><div><h3>Methods</h3><div>This cross-sectional study was conducted at Hospital of Chengdu University of TCM between January 2024 and March 2024, and included the youth aged from 18 to 39 years old. Demographic characteristics and KAP scores were collected via self-administered questionnaires.</div></div><div><h3>Results</h3><div>A total of 561 valid questionnaires were analyzed. Of these, 292 respondents (52.05 %) were female, and 317 (56.51 %) had experienced ACL injuries or other related sports injuries. The mean scores for knowledge, attitudes, and practices were 19.99 ± 9.28 (possible range: 0–24), 30.34 ± 7.83 (possible range: 9–45), and 25.48 ± 7.40 (possible range: 7–35), respectively. Correlation analyses revealed significant positive correlations between knowledge and attitude (r = 0.506, P &lt; 0.001), knowledge and practice (r = 0.612, P &lt; 0.001), and attitude and practice (r = 0.546, P &lt; 0.001). Structural equation modeling (SEM) indicated direct effects of knowledge on both attitude (β = 1.235, P &lt; 0.001) and practice (β = 0.817, P &lt; 0.001), as well as of attitude on practice (β = 0.490, P &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>The youth demonstrated adequate knowledge but moderate attitudes and practices regarding ACL injuries. Educational interventions targeting psychological factors, attitudes, and the translation of knowledge into consistent preventive behaviors are essential to mitigate injury risks and improve management outcomes among the youth.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100866"},"PeriodicalIF":2.4,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143419477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Closed negative pressure wound therapy vs standard primary closure in emergency laparotomies: A prospective case-control study","authors":"C. Cremonini,&nbsp;S. Strambi,&nbsp;S. Musetti,&nbsp;L. Cobuccio,&nbsp;D. Tartaglia,&nbsp;F. Coccolini,&nbsp;M. Chiarugi","doi":"10.1016/j.jtv.2025.100864","DOIUrl":"10.1016/j.jtv.2025.100864","url":null,"abstract":"","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100864"},"PeriodicalIF":2.4,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143372690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}