Journal of tissue viability最新文献

{"title":"Corrigendum to \"Cognitive gaps and educational needs in foot self-care among patients with diabetic foot from a health literacy perspective: A qualitative study\" [J Tissue Viabil 34 (2025) 100960].","authors":"Xiaodan Lin, Xianghao Chen, Yuantian Li, Shumin He, Haidan Xie, Xiaozhou Zhou","doi":"10.1016/j.jtv.2025.100972","DOIUrl":"10.1016/j.jtv.2025.100972","url":null,"abstract":"","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":" ","pages":"100972"},"PeriodicalIF":2.4,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145549676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic accuracy of artificial intelligence to identify diabetic foot ulcers: A systematic review and meta-analysis","authors":"Zhigang Chen ,&nbsp;Xinliang Liu ,&nbsp;Simeng Li ,&nbsp;Zhenheng Wu ,&nbsp;Haifen Tan ,&nbsp;Fuqian Yu ,&nbsp;Dongmei Wang ,&nbsp;Changhua Zhu ,&nbsp;Pengfei Lin","doi":"10.1016/j.jtv.2025.100975","DOIUrl":"10.1016/j.jtv.2025.100975","url":null,"abstract":"<div><h3>Background</h3><div>The accuracy of artificial intelligence (AI) in diagnosing diabetic foot ulcers (DFUs) in dermatology remains uncertain.</div></div><div><h3>Objective</h3><div>To summarize the diagnostic accuracy of AI for DFUs and to provide specific theoretical basis for clinical diagnosis.</div></div><div><h3>Methods</h3><div>From the inception of the database up to November 3, 2024, we performed an extensive search across several databases, including PubMed, Web of Science (WoS), Embase, Scopus, the Cochrane Library, Wanfang, and the China National Knowledge Infrastructure (CNKI). To assess the overall efficacy of AI in diagnostic testing, we utilized combined metrics of sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and the area under the curve (AUC). Finally, we assessed the presence of publication bias using the Deeks' funnel plot asymmetry test.</div></div><div><h3>Results</h3><div>In this meta-analysis, a total of 16 references were identified. The summary diagnostic performance is as follows: sensitivity, 0.89 (95 % CI, 0.85–0.92); specificity, 0.93 (95 % CI, 0.90–0.95); PLR, 6.31 (95 % CI, 5.67–7.02); NLR, 0.14 (95 % CI, 0.12–0.15); DOR, 58.22 (95 % CI, 50.18–67.55); and AUC, 0.97 (95 % CI, 0.95–0.98). Subgroup analysis showed the best performance observed in studies with 300 to 1000 samples. Furthermore, the Fagan plot indicates an increase in post-test probability from 10 % pre-test to 59 % post-test.</div></div><div><h3>Conclusion</h3><div>In summary, our results suggest that AI has high accuracy in diagnosing DFUs.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"35 1","pages":"Article 100975"},"PeriodicalIF":2.4,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146053066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic factors of pressure injury: a scoping review","authors":"Yuki Fukui ,&nbsp;Toshiaki Takahashi ,&nbsp;Mao Kunimitsu ,&nbsp;Miyako Muta ,&nbsp;Sotaro Shimada ,&nbsp;Gojiro Nakagami","doi":"10.1016/j.jtv.2026.100984","DOIUrl":"10.1016/j.jtv.2026.100984","url":null,"abstract":"<div><h3>Aim</h3><div>This scoping review aimed to comprehensively map prognostic factors of pressure injuries and to synthesize reported evidence on their predictive performance to identify research gaps.</div></div><div><h3>Materials and methods</h3><div>Studies published between January 2001 and April 2025 were identified from databases using the PRISMA-ScR methodology. Eligible articles investigated the prognostic factors for pressure injuries.</div></div><div><h3>Results</h3><div>A total of 54 studies were included. Outcome definitions varied and included complete healing, time to heal, changes in wound area or depth, and assessment tool scores. Predictive performance was evaluated in 18 studies; however, one reported an area under the curve of ≥0.9. Prognostic factors were categorized according to their acquisition methods: Category A, clinical chart data or questionnaires (age, mobility, and pressure injury depth and size were reported most frequently); Category B, medical imaging (thermographic temperature differences and ultrasonographic findings were reported most frequently); and Category C, biomarkers (biofilm was most frequently reported). One study showed that combining factors obtained through different methods—none individually associated with outcomes—yielded a statistically significant prognostic value. Nineteen studies distinguished between superficial and deep-pressure injuries.</div></div><div><h3>Conclusions</h3><div>This review provides a comprehensive overview of the prognostic factors and predictive performance for pressure injuries, highlighting key research gaps. Prognosis was broadly defined, underscoring the need for standardization, although prognostic factors could still be mapped by acquisition method. Predictive performance was generally limited, highlighting the need for improvement. Stratifying prognostic factors by wound characteristics, such as depth, and integrating those from multiple acquisition methods may help address these gaps.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"35 1","pages":"Article 100984"},"PeriodicalIF":2.4,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146090693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to Investigating UK packing practices for cavities resulting from the incision and drainage of perianal abscesses, a case for deimplementation? [Journal of Tissue Viability 2025 Nov;34(4):100965, doi: 10.1016/j.jtv.2025.100965].","authors":"J Dumville, K Newton, J Mullings, P Wilson","doi":"10.1016/j.jtv.2025.100980","DOIUrl":"10.1016/j.jtv.2025.100980","url":null,"abstract":"","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":" ","pages":"100980"},"PeriodicalIF":2.4,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145751886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lessons from earth, reimagined for space: Why pressure ulcer science must follow us beyond the atmosphere.","authors":"Pinar Avsar, Kerem Osman Cubuk, Tom O'Connor, Hannah Wilson, Declan Patton, Zena Moore","doi":"10.1016/j.jtv.2025.100978","DOIUrl":"10.1016/j.jtv.2025.100978","url":null,"abstract":"","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":" ","pages":"100978"},"PeriodicalIF":2.4,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145800213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research progress of exosomes derived from platelet-rich plasma in angiogenesis of chronic diabetic wounds","authors":"Linlin Feng ,&nbsp;Yuan Xue ,&nbsp;Jingwen Kuang ,&nbsp;Huiyi Tang ,&nbsp;Pengcheng Xu","doi":"10.1016/j.jtv.2026.100985","DOIUrl":"10.1016/j.jtv.2026.100985","url":null,"abstract":"<div><div>With the ageing of the population, the incidence rate of diabetes is also increasing an-nually. Difficulties in healing chronic wounds are common complications of diabetes and are highly detrimental to people's quality of life. There are many reasons why wounds are diffi-cult to heal. Among these factors, one of the most important is the obstruction of angiogene-sis. As important players in wound healing, platelets not only promote tissue regeneration and repair but also participate in the regeneration of blood vessels, playing an important role in improving wound healing in chronic diabetes. Research has revealed that the use of exosomes derived from platelet-rich plasma can significantly improve chronic wound healing in patients with diabetes. Therefore, exosomes derived from platelet-rich plasma have emerged as new targets for the treatment of chronic diabetic wounds. However, the standardized isolation, characterization, mechanism of action, and application of exosomes derived from platelet-rich plasma in the study of angiogenesis in chronic diabetic wounds have not been systematically described. This article reviews the latest advancements in understanding the mechanism by which exosomes derived from platelet-rich plasma promote angiogenesis in chronic diabetic wounds. It also reviews the therapeutic effects of PRP-Exos (hydrogel) and other novel applications. Consequently, this study systematically examines the research status and gaps in the understanding of how exosomes derived from platelet-rich plasma promote angiogenesis in chronic diabetic wounds, aiming to provide a theoretical basis for the further development and application of these exosomes in clinical treatment.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"35 1","pages":"Article 100985"},"PeriodicalIF":2.4,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145952496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantifying seated buttock tissue response to commercial wheelchair cushions through MRI and pressure mapping analyses","authors":"Sharon Eve Sonenblum ,&nbsp;Mary Shea-Stifel ,&nbsp;Kelly Waugh ,&nbsp;Trevor Dyson-Hudson","doi":"10.1016/j.jtv.2026.100983","DOIUrl":"10.1016/j.jtv.2026.100983","url":null,"abstract":"<div><h3>Objective</h3><div>To describe how different wheelchair cushion designs impact interface pressure and buttock tissue deformation during sitting.</div></div><div><h3>Materials &amp; methods</h3><div>43 chronic full-time wheelchair users at high risk for pressure injuries were studied in an unloaded/suspended condition and on the Acta-Embrace, HR45, Jay J2 Deep Contour, Java, Matrx Vi, and/or the Roho HP cushions in randomized order. FONAR Upright MRI scans were used to measure seated soft tissue anatomy, and interface pressure mapping was used to measure peak pressure index (PPI) and pressure gradient.</div></div><div><h3>Results</h3><div>Median unloaded bulk tissue thickness beneath the ischium was 36.0 mm, decreasing by 53% when loaded. Tissue thickness under the ischium varied significantly between the Java (an off-loading design) and other pressure redistributing cushions (HR45, J2 Deep Contour, Matrx Vi) during upright sitting.</div><div>Greater bulk tissue thickness correlated with increased proximal thigh thickness and reduced deformation under the ischium. Average PPI and pressure gradient were 116.2 ± 44.8 mmHg and 26.1 ± 17.8 mmHg, respectively. Matrx Vi exhibited significantly higher PPIs and gradients despite comparable deformation. Both PPI and gradient showed weak inverse correlations with tissue thickness (r = −0.276, p = 0.002; r = −0.321, p &lt; 0.001). Both were associated with greater immersion on most cushions.</div></div><div><h3>Conclusion</h3><div>The wheelchair cushions investigated showed comparable tissue deformation and PPI, though individuals with greater tissue thickness experienced less deformation. While participants experienced similar maximal tissue deformation across cushions, pressure gradients provided a more reliable representation of internal tissue response than PPI. Different cushion designs influenced load distribution uniquely despite similar overall tissue response, with notable differences between off-loading and pressure redistribution approaches. Regular skin checks remain essential for all wheelchair users.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"35 1","pages":"Article 100983"},"PeriodicalIF":2.4,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145966538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between microbiota and healing status in diabetes-related foot ulcers treated with Trigona honey","authors":"Sukarni Sukarni ,&nbsp;Mao Kunimitsu ,&nbsp;Kazuhiro Ogai ,&nbsp;Delima Fajar Liana ,&nbsp;Mahyarudin Mahyarudin ,&nbsp;Muhammad Aminuddin ,&nbsp;Kanae Mukai ,&nbsp;Haryanto Haryanto ,&nbsp;Suriadi Jais ,&nbsp;Makoto Oe","doi":"10.1016/j.jtv.2025.100981","DOIUrl":"10.1016/j.jtv.2025.100981","url":null,"abstract":"<div><h3>Aims</h3><div>Diabetes-related foot ulcers (DFUs) are a major complication of diabetes, and treatment with honey, which has antimicrobial properties, has been utilized in patients. However, the effects have been shown to vary, with the causes of these differences remaining unclear. Recently, microbiota has been reported to be associated with wound healing. Therefore, we hypothesized that differences in microbiota might explain the variations observed in response to honey. The present study aimed to investigate the relationship between the microbiota and the healing status in DFUs treated with Trigona honey.</div></div><div><h3>Methods</h3><div>A cohort study involving 12 DFUs categorized into healing and deteriorating groups was conducted. Wound and peri-wound microbiota observed at baseline and at 1 week later (after starting honey application) were investigated and then compared in the healing status.</div></div><div><h3>Results</h3><div><em>Enterococcus</em> was higher in the deteriorating group at baseline in the wound (<em>p</em> = 0.02), while <em>Corynebacterium</em> was higher in the healing group at 1 week later in the peri-wound skin (<em>p</em> = 0.02). Changes in the relative abundance of <em>Prevotella</em> and <em>Brevundimonas</em> in the peri-wound skin significantly differed based on the healing status.</div></div><div><h3>Conclusion</h3><div>The findings suggest that the honey's effects might differ based on the composition of the wound microbiota, and they highlight the bacterial interactions with the changes in the wound and peri-wound skin environment induced by the honey. These results also imply that honey therapy on its own may not be enough for treating DFUs. This study is limited by the small sample size and short follow-up period; further research will need to explore combined treatment strategies and long-term microbiota dynamics to improve DFU management.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"35 1","pages":"Article 100981"},"PeriodicalIF":2.4,"publicationDate":"2025-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145827262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The mechanism by which negative pressure wound therapy promotes wound healing","authors":"Ying Zeng ,&nbsp;Jianjian Tu ,&nbsp;Jichao Qin","doi":"10.1016/j.jtv.2025.100982","DOIUrl":"10.1016/j.jtv.2025.100982","url":null,"abstract":"<div><div>Negative pressure wound therapy (NPWT) has demonstrated substantial advantages in a variety of clinical settings, including the management of acute and chronic wounds, open injuries with exposed bone, nerves, or tendons, and implant-associated infections in orthopedics. Although numerous studies have reported the beneficial effects of NPWT in controlling wound infections and infections related to orthopedic implants, the underlying molecular and cellular mechanisms remain incompletely understood and require further investigation. Given its widespread clinical use, a comprehensive understanding of the biological effects of NPWT is essential to ensuring its rational and optimized application in clinical practice. This review summarizes the potential mechanisms through which NPWT facilitates wound healing and provides insights to inform both clinical use and future research.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"35 1","pages":"Article 100982"},"PeriodicalIF":2.4,"publicationDate":"2025-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145794254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Be there or be square: Should we adopt non-rectangular dressing shapes in single-use negative pressure wound therapy?","authors":"Ofek Barzilay ,&nbsp;Amit Gefen","doi":"10.1016/j.jtv.2025.100977","DOIUrl":"10.1016/j.jtv.2025.100977","url":null,"abstract":"<div><h3>Background</h3><div>Single-use negative-pressure wound therapy (suNPWT) dressings for closed surgical incisions are predominantly rectangular, despite long-time evidence from biomechanics that sharp or small-radius corners generate localized stress concentrations in underlying tissues. Optimizing dressing geometry and stiffness distribution may reduce the peri-incisional stress concentrations and improve closure.</div></div><div><h3>Objectives</h3><div>To determine how dressing shape and regional stiffness variations influence the peri-wound skin stresses and stress concentrations and the incision closure biomechanics under a negative pressure level of −125 mmHg.</div></div><div><h3>Methods</h3><div>A validated three-dimensional finite element model of a sutured midline incision was developed. Five homogeneous dressing shapes (rectangular, circular, elliptical, stadium, and dome) of identical contact area and material properties were compared for reduction in peak lateral skin stresses (ΔS). The best-performing dressing shape underwent further testing in eight stiffness configurations (homogeneous, or with stiffer/softer peripheral regions in symmetric or axisymmetric patterns). The lateral displacement of the peri-wound skin was used as a measure for the closure work. A sensitivity analysis was conducted on chosen model variants for broader transferability and for exploring potential covariance between dressing shape and material properties.</div></div><div><h3>Results</h3><div>Among the homogeneous dressing shapes, the circular dressing achieved the greatest stress reduction (ΔS = 2.9 %) versus the rectangular control (0.9 %). In the circular form, incorporating a stiffer peripheral symmetric ring around a softer core improved performance (ΔS = 3.2 %) while maintaining substantial lateral displacement (3.35 mm), achieving an optimal combination of stress relief with closure assistance. A fully stiff homogeneous dressing maximized the ΔS (6.5 %) but provided negligible closure support, whereas a fully soft dressing behaved conversely. The sensitivity analysis did not change these quantitative rankings across the studied model variants.</div></div><div><h3>Conclusions</h3><div>Eliminating sharp or small-radius geometric discontinuities and tuning the regional stiffness can markedly attenuate peri-incisional stresses without compromising the contribution of the dressing to the closure work. Circular suNPWT dressings with a peripheral stiffer ring offer a biomechanically superior, manufacturable alternative to conventional rectangular designs, warranting further pre-clinical and clinical evaluations.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"35 1","pages":"Article 100977"},"PeriodicalIF":2.4,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145691413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}