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Pattern analysis of hospital nurses' knowledge, attitudes, and practices regarding incontinence-associated dermatitis 医院护士对尿失禁相关性皮炎的知识、态度和做法的模式分析
IF 2.4 3区 医学 Q2 DERMATOLOGY Pub Date : 2025-04-03 DOI: 10.1016/j.jtv.2025.100899
Weifang Xu , Xujing Wu , Shi Xu , Yali Yan , Chao Liu , Yen-Ching Chuang , Fuman Cai

Purpose

To analyze hospital nurses' knowledge, attitudes, and practices regarding incontinence-associated dermatitis (KAP-IAD).

Methods

This study utilized responses from hospital nurses to the Knowledge, Attitudes, and Practices of Incontinence-Associated Dermatitis Questionnaire (KAP-IAD-Q). Three clustering methods, Hierarchical Clustering on Principal Components (HCPC), K-means, and Partitioning Around Medoids (PAM), were applied to analyze the correlations of KAP-IAD. A classification method was used to explain the underlying behavioral patterns behind these correlations.

Results

Two clusters were found to be most appropriate. Decision attributes (D) were generated for the KAP-IAD data using the three clustering methods: HCPC, K-means, and PAM. Three datasets with categorical labels were generated, and predictive models and decision rules were established for each dataset using the Rough Set (RS) method. The PAM method demonstrated the highest accuracy among the three datasets. After five rounds of stochastic modeling, 57 decision rules were generated. Additionally, patterns or rules with a support threshold of 50 or more, as discussed by domain experts, were considered the primary behaviors or rules.

Conclusions

Our study suggests clear decision rules for KAP-IAD nursing practice, which have been absent in previous research. The key variables and rules identified can serve as a guide for KAP-IAD nursing practice, as well as for recognizing the etiology, risk factors, and key influences of dermatitis associated with KAP-IAD in nursing practice. This study provides an important management approach for the prevention and treatment of incontinence-associated dermatitis.
目的分析医院护士对尿失禁相关性皮炎(KAP-IAD)的知识、态度和行为。方法本研究采用医院护士对失禁相关性皮炎的知识、态度和实践问卷(KAP-IAD-Q)进行问卷调查。采用主成分层次聚类(HCPC)、k均值聚类(K-means)和围绕介质划分(PAM)三种聚类方法分析了KAP-IAD的相关性。一种分类方法被用来解释这些相关性背后的潜在行为模式。结果两个聚类最合适。使用HCPC、K-means和PAM三种聚类方法为KAP-IAD数据生成决策属性(D)。生成带有分类标签的3个数据集,利用粗糙集(RS)方法对每个数据集建立预测模型和决策规则。在三个数据集中,PAM方法的准确率最高。经过5轮随机建模,共生成57条决策规则。此外,正如领域专家所讨论的那样,支持阈值为50或更多的模式或规则被认为是主要的行为或规则。结论我们的研究为KAP-IAD护理实践提供了明确的决策规则,这是以往研究缺乏的。确定的关键变量和规则可作为KAP-IAD护理实践的指导,以及在护理实践中认识KAP-IAD相关皮炎的病因、危险因素和关键影响因素。本研究为预防和治疗尿失禁相关性皮炎提供了重要的管理方法。
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引用次数: 0
Comparative effects of epidermal and fibroblast growth factor-infused collagen patches on wound healing in a full-thickness rat model 表皮与成纤维细胞生长因子灌注胶原贴片对大鼠全层模型创面愈合的影响
IF 2.4 3区 医学 Q2 DERMATOLOGY Pub Date : 2025-04-03 DOI: 10.1016/j.jtv.2025.100903
Fahri Sabanciogullarindan , Mehmet Bozkurt , Nilsen Yildirim Erdogan , Yasar Samet Gokceoglu , Percin Karakol

Objective

This study aimed to investigate the effects of Epidermal Growth Factor (EGF)- and Fibroblast Growth Factor (FGF)-infused collagen patches on wound healing in an experimental rat model. The focus was on acute and chronic inflammation, granulation tissue formation, fibroblast maturation, re-epithelialization, neovascularization, and collagen remodeling.

Methods

Full-thickness cranial wounds (12 mm) were created on the dorsal regions of 21 male Wistar rats and divided into four groups: Group 1 (collagen patch alone), Group 2 (collagen + EGF), Group 3 (collagen + FGF). The kaudal defects served as a chronic wound model with secondary intention healing, monitored for 21 days. Tissue biopsies were collected on days 3, 7, and 21. Histopathological evaluation included inflammation scores, granulation tissue formation, fibroblast maturation, re-epithelialization, neovascularization, and Type 1/Type 3 collagen ratio. Data were analyzed using one-way ANOVA, Kruskal–Wallis test, and other appropriate post hoc tests. Statistical significance was set at p < 0.05.

Results

Acute inflammation significantly decreased in Group 3 on day 7 (p = 0.001), while chronic inflammation was minimal by day 21 in Groups 1 and 3. Group 2 showed the highest granulation tissue formation on day 21 (p < 0.05). Fibroblast maturation peaked in Group 3 on day 21 (p = 0.004). Re-epithelialization was complete in Groups 1 and 3 by day 21, significantly outperforming Group 2 (p < 0.005). Group 3 demonstrated superior collagen deposition and the highest Type 1/Type 3 collagen ratio (p < 0.05).

Conclusions

FGF-infused collagen patches significantly improved fibroblast maturation, epithelialization, and collagen remodeling, outperforming EGF and standalone collagen patches. These findings highlight the potential of FGF as a therapeutic agent in wound healing.
目的 本研究旨在探讨表皮生长因子(EGF)和成纤维细胞生长因子(FGF)注入胶原贴片对实验大鼠模型伤口愈合的影响。重点是急性和慢性炎症、肉芽组织形成、成纤维细胞成熟、再上皮化、新生血管和胶原重塑。方法在 21 只雄性 Wistar 大鼠的背侧创建全厚颅骨伤口(12 毫米),并将其分为四组:第 1 组(仅胶原贴片)、第 2 组(胶原蛋白 + EGF)、第 3 组(胶原蛋白 + FGF)。将kaudal缺损作为慢性伤口模型,进行21天的二次意向性愈合监测。在第 3、7 和 21 天收集组织活检。组织病理学评估包括炎症评分、肉芽组织形成、成纤维细胞成熟、再上皮化、新生血管和 1 型/3 型胶原比率。数据分析采用单因素方差分析、Kruskal-Wallis 检验和其他适当的事后检验。结果第 3 组的急性炎症在第 7 天明显减轻(p = 0.001),而第 1 组和第 3 组的慢性炎症在第 21 天时已降到最低。第 2 组在第 21 天肉芽组织形成最多(p < 0.05)。第 3 组的成纤维细胞成熟在第 21 天达到高峰(p = 0.004)。第 1 组和第 3 组在第 21 天时完成了再上皮化,明显优于第 2 组(p = 0.005)。结论注入 FGF 的胶原贴片能显著改善成纤维细胞成熟、上皮化和胶原重塑,其效果优于 EGF 和单独的胶原贴片。这些发现凸显了 FGF 作为伤口愈合治疗剂的潜力。
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引用次数: 0
Factors influencing Patient engagement in preventing pressure injuries: A cross-sectional study in Orthopedic inpatients 影响患者参与预防压力性损伤的因素:骨科住院患者的横断面研究
IF 2.4 3区 医学 Q2 DERMATOLOGY Pub Date : 2025-04-03 DOI: 10.1016/j.jtv.2025.100902
Ying Liu , Rong Hu , Peifang Li , Lin Zhang , Liqun Wang , Junhong Qu , Xingcui Pu , Ning Ning , Jiali Chen

Aim

This study aimed to explore the level of patients’ engagement behaviours in preventing pressure injury (PI) and the influencing factors related to it.

Background

The importance of “Patient and Family Engagement” was recognized as one of the key components in the outline of the 2023 Global Patient Safety Report. PIs were common and concerning patient safety events in Orthopaedics department. Active patient participation behaviour can effectively prevent the occurrence of PIs.

Method

This was a cross-sectional study involving 366 participants from Orthopaedics in China who has high level of risk in PI. The behavioural level of patients' participation in PI prevention was measured using a research tool designed by the research team. Based on the theory of planned behaviour, the possible influencing factors were determined, and the corresponding research tools were selected for evaluation. Univariate analysis, correlation analysis and multiple stepwise regression were used to determine the influencing factors of patients’ participation behaviour with SPSS 25.0.

Results

The total score of orthopaedic inpatients participating in PI preventive behaviour was 89.45 ± 10.64, with a scoring rate of 85.19 % (actual score/maximum possible score × 100 %), indicating relatively high adherence. Multiple regression analysis revealed that social support showed the strongest positive association (β = 0.291, P < 0.001), suggesting enhanced support networks facilitate engagement. Participation attitude (β = 0.211, P < 0.001) and health literacy (β = 0.233, P < 0.001) were key cognitive facilitators. Unexpectedly, cohabitation with children exhibited negative correlation (β = −0.141, P = 0.001), potentially indicating caregiving role transfer. Inter-hospital transfers (β = −0.120, P = 0.004) and medium-length stays (4–7 days, β = −0.089, P = 0.010) were inversely related, possibly reflecting care continuity challenges. Social Security recipients demonstrated greater participation (β = 0.108, P = 0.009), highlighting socioeconomic influences.

Conclusion

Our findings may guide clinical healthcare providers to develop more targeted interventions to promote patient engagement in self-care, including encouraging family members to involve in PI prevention with patients, improving patients’ attitude of participation, and supporting more health education of PI prevention. It was a potential suggestion for patient participation behaviour in medical services to prevent other types of adverse events as well.
目的探讨患者参与行为在预防压力性损伤(PI)中的水平及其影响因素。《2023年全球患者安全报告》大纲认为,“患者和家庭参与”的重要性是关键组成部分之一。PIs是骨科常见且涉及患者安全的事件。积极的患者参与行为可以有效预防pi的发生。方法本研究是一项横断面研究,涉及366名来自中国骨科的PI高危人群。使用研究小组设计的研究工具测量患者参与PI预防的行为水平。基于计划行为理论,确定可能的影响因素,并选择相应的研究工具进行评价。采用SPSS 25.0软件对患者参与行为的影响因素进行单因素分析、相关分析和多元逐步回归分析。结果骨科住院患者参与PI预防行为的总得分为89.45±10.64,评分率为85.19%(实际得分/最大可能得分× 100%),依从性较高。多元回归分析显示,社会支持表现出最强的正相关(β = 0.291, P <;0.001),这表明增强的支持网络促进了参与。参与态度(β = 0.211, P <;0.001)和健康素养(β = 0.233, P <;0.001)是关键的认知促进因素。出乎意料的是,与孩子的同居表现出负相关(β = - 0.141, P = 0.001),可能表明照顾角色转移。医院间转院(β = - 0.120, P = 0.004)和中等住院天数(4-7天,β = - 0.089, P = 0.010)呈负相关,可能反映了护理连续性的挑战。社会保障接受者表现出更高的参与度(β = 0.108, P = 0.009),突出了社会经济的影响。结论本研究结果可指导临床医疗服务提供者制定更有针对性的干预措施,包括鼓励家庭成员与患者一起参与PI预防,改善患者的参与态度,并支持更多的PI预防健康教育,以促进患者参与自我护理。这是一个潜在的建议,病人参与医疗服务的行为,以防止其他类型的不良事件。
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引用次数: 0
Review of the effects of far infrared radiation on muscle injury caused by centrifugal exercise 远红外辐射对离心运动所致肌肉损伤影响的研究进展
IF 2.4 3区 医学 Q2 DERMATOLOGY Pub Date : 2025-04-02 DOI: 10.1016/j.jtv.2025.100900
Lin Ren , Ran He

Objective

Explore the recovery effect of FIR on high-intensity centrifugal contraction or lower limb muscle fiber injury caused by long-term endurance exercise.

Methods

Collect and organize relevant literature on FIR, and explore the recovery effect and possible mechanism of FIR intervention on subtle muscle fiber damage caused by exercise.

Result

FIR can reduce COX-2, inhibit PGE2, accelerate hydrogen peroxide clearance, alleviate pain caused by various conditions, promote cell proliferation, and increase blood flow; Among the two main processing tools of FIR, FIR lighting fixtures that are exposed to radiation for 30 min a day after exercise can effectively alleviate the human induced DOMS condition, while FIR clothing needs to be worn for 9 h a day to have the effect of slowing down DOMS.

Conclusion

FIR may be developed into one of the auxiliary strategies for warm-up before competitions and after intermission in the future.
目的探讨FIR对长期耐力运动引起的高强度离心收缩或下肢肌纤维损伤的恢复作用。方法收集整理有关FIR的相关文献,探讨FIR干预运动引起的微细肌纤维损伤的恢复效果及可能机制。结果fir能降低COX-2,抑制PGE2,加速过氧化氢清除,减轻各种疾病引起的疼痛,促进细胞增殖,增加血流量;在FIR的两种主要加工工具中,运动后每天照射30分钟的FIR照明灯具可以有效缓解人为引起的DOMS,而FIR服装则需要每天穿9小时才能起到减缓DOMS的效果。结论fir可作为赛前和中场休息后热身的辅助策略之一。
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引用次数: 0
Randomized clinical trial of the efficacy of the EmoLED medical device in the treatment of stage 2 and stage 3 pressure ulcers: The RISE_UP study EmoLED医疗器械治疗2期和3期压疮疗效的随机临床试验:RISE_UP研究
IF 2.4 3区 医学 Q2 DERMATOLOGY Pub Date : 2025-03-26 DOI: 10.1016/j.jtv.2025.100895
Hamilton Dollaku , Mara Dalladonna , Marika Giuliano , Michele Rossi , Paola Barbetti , Maria Sipontina Marcolongo , Emanuele Buccione , Paolo Iovino , Claudio Macchi

Aim of the study

Pressure ulcers are an important public health issue, impacting quality of life and causing health deterioration. Blue light photobiomodulation has been shown promoting wound healing in vascular, diabetic, rheumatologic ulcers and lesions in spinal cord injury patients. Based on these preliminary results, this study was developed to assess the effectiveness of blue light therapy in second and third stage pressure ulcers.

Materials and methods

This study was a randomized controlled trial enrolling hospitalized patients with poor mobility. The intervention group included blue light treatment in addition to standard care, three times a week, for 4 consecutive weeks. The primary objective is the difference in the healing process by measuring the average difference of the lesion's PUSH score between the first and the last visit.

Results

The analysis shows that the mean PUSH reduction and the probability of belonging to responder patients were higher in the treatment group. A latent profile analysis that identifies two trajectory classes based on treatment response, shows an association in the probability of following best trajectory for the treatment group (30 % vs 2 %).

Conclusions

The result shows that blue light photobiomodulation promotes recovery of tissue repair in pressure ulcers, and in stabilizing wounds that would otherwise worsen despite standard of care treatment. This therapy may be a valuable contribution to the daily management of pressure lesions since it has an excellent safety profile and the addition of this therapy to a treatment program may speed healing, improving the quality of life.
(Clinicaltrials.gov Ref. numb.: NCT05130814)
研究目的压疮是一个重要的公共卫生问题,影响生活质量并导致健康恶化。蓝光光生物调节已被证明可促进血管、糖尿病、风湿病溃疡和脊髓损伤患者的伤口愈合。基于这些初步结果,本研究旨在评估蓝光治疗二期和三期压疮的有效性。材料和方法本研究是一项随机对照试验,纳入了活动能力差的住院患者。干预组在标准治疗的基础上进行蓝光治疗,每周三次,连续4周。主要目的是通过测量第一次和最后一次访问之间病变PUSH评分的平均差异来衡量愈合过程的差异。结果分析显示,治疗组的平均PUSH降低率和属于应答患者的概率较高。根据治疗反应确定两种轨迹类别的潜在剖面分析显示,治疗组遵循最佳轨迹的概率存在关联(30% vs 2%)。结论蓝光光生物调节可促进压疮组织修复的恢复,并可稳定经标准护理治疗后仍会恶化的创面。这种疗法可能对压力性病变的日常管理有价值,因为它具有良好的安全性,并且在治疗方案中加入这种疗法可能会加速愈合,提高生活质量。: NCT05130814)
{"title":"Randomized clinical trial of the efficacy of the EmoLED medical device in the treatment of stage 2 and stage 3 pressure ulcers: The RISE_UP study","authors":"Hamilton Dollaku ,&nbsp;Mara Dalladonna ,&nbsp;Marika Giuliano ,&nbsp;Michele Rossi ,&nbsp;Paola Barbetti ,&nbsp;Maria Sipontina Marcolongo ,&nbsp;Emanuele Buccione ,&nbsp;Paolo Iovino ,&nbsp;Claudio Macchi","doi":"10.1016/j.jtv.2025.100895","DOIUrl":"10.1016/j.jtv.2025.100895","url":null,"abstract":"<div><h3>Aim of the study</h3><div>Pressure ulcers are an important public health issue, impacting quality of life and causing health deterioration. Blue light photobiomodulation has been shown promoting wound healing in vascular, diabetic, rheumatologic ulcers and lesions in spinal cord injury patients. Based on these preliminary results, this study was developed to assess the effectiveness of blue light therapy in second and third stage pressure ulcers.</div></div><div><h3>Materials and methods</h3><div>This study was a randomized controlled trial enrolling hospitalized patients with poor mobility. The intervention group included blue light treatment in addition to standard care, three times a week, for 4 consecutive weeks. The primary objective is the difference in the healing process by measuring the average difference of the lesion's PUSH score between the first and the last visit.</div></div><div><h3>Results</h3><div>The analysis shows that the mean PUSH reduction and the probability of belonging to responder patients were higher in the treatment group. A latent profile analysis that identifies two trajectory classes based on treatment response, shows an association in the probability of following best trajectory for the treatment group (30 % vs 2 %).</div></div><div><h3>Conclusions</h3><div>The result shows that blue light photobiomodulation promotes recovery of tissue repair in pressure ulcers, and in stabilizing wounds that would otherwise worsen despite standard of care treatment. This therapy may be a valuable contribution to the daily management of pressure lesions since it has an excellent safety profile and the addition of this therapy to a treatment program may speed healing, improving the quality of life.</div><div>(<span><span>Clinicaltrials.gov</span><svg><path></path></svg></span> Ref. numb.: NCT05130814)</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 3","pages":"Article 100895"},"PeriodicalIF":2.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143724887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of the structural and histopathological challenges of binary electrospun PET-based nanofibers for tissue engineering applications 组织工程应用中基于pet的二元电纺纳米纤维的结构和组织病理学挑战评估
IF 2.4 3区 医学 Q2 DERMATOLOGY Pub Date : 2025-03-25 DOI: 10.1016/j.jtv.2025.100888
Afsaneh Jahani , Davod Mohebbi-Kalhori , Farkhonde Sarhaddi , Gholam Hosein Kazemzadeh , Reza Taheri , Mehdi Ahmadi , Nafiseh Jirofti
Tissue engineering and regenerative medicine aim to address tissue lesions and organ degenerations, enhancing clinical outcomes by restoring damaged tissues and functionalities. Recent progress in materials science and medicine has led to the development of regenerative engineering, revolutionizing the production of polymeric artificial scaffolds by electrospinning method, which mimic the extracellular matrix (ECM). Polyurethane (PU) is recognized for its elastic nature, comprising soft and hard segments, and possesses bioactive as well as biocompatible properties. Polycaprolactone (PCL), on the other hand, is a non-toxic polymer with a viscous nature, known for its favorable mechanical properties. This study focuses on the comprehensive histological evaluation of binary electrospun PET-based nanofiber scaffolds, as widely used in tissue engineering. The structural analysis involved FE-SEM imaging, porosity measurement, FTIR, and DSC examinations. In vitro assessments included degradation rates, water uptake, cell viability, morphological cell examination, and cell attachment studies. Additionally, scaffolds were subcutaneously implanted in rats for pathological examination. After a 30 days implantation period, histological and pathological parameters such as edema, inflammation, foreign body giant cell reaction, fibrosis, necrosis, and calcification were evaluated. The results highlight the successful application of blend electrospinning in producing PET/PCL and PET/PU nanofiber scaffolds with various composition ratios. FE-SEM imaging revealed uniform nanostructures without bead formation. Histological analysis showed favorable biocompatibility, with the PET/PCL (25:75) composition demonstrating superior structural characteristics compared to other ratios. The cell studies indicated that PET-based nanofiber scaffolds exhibited suitable cell viability and attachment, underscoring their potential for tissue engineering applications.
组织工程和再生医学旨在解决组织病变和器官变性,通过恢复受损组织和功能来提高临床效果。近年来,材料科学和医学的进步促进了再生工程的发展,通过静电纺丝方法模拟细胞外基质(ECM),彻底改变了聚合物人工支架的生产。聚氨酯(PU)被认为具有弹性,包括软段和硬段,并具有生物活性和生物相容性。另一方面,聚己内酯(PCL)是一种具有粘性的无毒聚合物,以其良好的机械性能而闻名。本研究对在组织工程中广泛应用的基于pet的二元电纺纳米纤维支架进行了组织学综合评价。结构分析包括FE-SEM成像、孔隙度测量、FTIR和DSC检查。体外评估包括降解率、吸水率、细胞活力、形态学细胞检查和细胞附着研究。大鼠皮下植入支架进行病理检查。植入期30 d后,观察水肿、炎症、异物巨细胞反应、纤维化、坏死、钙化等组织学病理指标。结果表明,共混静电纺丝技术在制备不同配比的PET/PCL和PET/PU纳米纤维支架中的成功应用。FE-SEM成像显示纳米结构均匀,未形成珠状结构。组织学分析显示良好的生物相容性,PET/PCL(25:75)组成与其他比例相比具有优越的结构特征。细胞研究表明,pet基纳米纤维支架具有良好的细胞活力和附着性,具有组织工程应用潜力。
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引用次数: 0
Machine learning methods for determining skin age: A systematic review 确定皮肤年龄的机器学习方法:系统综述
IF 2.4 3区 医学 Q2 DERMATOLOGY Pub Date : 2025-03-22 DOI: 10.1016/j.jtv.2025.100887
Eric McMullen , Rokhshid Aflaki , Pranav Jignesh Khatri , Dea Metko , Kyle Storm , Abu Bakar Butt , Mahan Maazi , Raghav Gupta , Rajan Grewal , Trevor Champagne

Aim

This systematic review explores how machine learning is used in determining skin aging, aiming to evaluate accuracy, limitations, and gaps in the current literature.

Materials and methods

OVID Embase, OVID Medline, IEEE Xplore, and ACM Digitial Library were searched from inception to March 16, 2024.

Results

A total of 1467 non-duplicate articles were screened, and 27 were ultimately included in the systematic review. The machine learning models exhibited a range of accuracies from a mean absolute error of 2.30–8.16 years. The most common approach was full facial image analysis, followed by non-image-based studies utilizing biomarkers such as the methylome and the proteome. The incorporation of dynamic facial expressions in the analysis was shown to improve the accuracy of age estimation, with a mean absolute error of 3.74. Confocal microscopy demonstrated potential for accurate skin aging estimation, with some studies achieving up to 85 % accuracy. Many studies were found with high PROBAST risk of bias scores, most commonly due to small sample sizes.

Conclusion

Future studies should aim for greater diversity in ethnicity and variables within datasets to improve generalizability.
目的:本系统综述探讨了机器学习如何用于确定皮肤老化,旨在评估当前文献中的准确性、局限性和空白。资料与方法检索自建库至2024年3月16日,检索自vid Embase、OVID Medline、IEEE explore和ACM数字图书馆。结果共筛选非重复文献1467篇,最终纳入系统评价27篇。机器学习模型的平均绝对误差范围为2.30-8.16年。最常见的方法是全面部图像分析,其次是利用甲基组和蛋白质组等生物标志物的非图像研究。在分析中加入动态面部表情可以提高年龄估计的准确性,平均绝对误差为3.74。共聚焦显微镜显示了准确估计皮肤老化的潜力,一些研究达到了85%的准确度。许多研究被发现具有较高的PROBAST偏倚风险评分,最常见的原因是样本量小。结论:未来的研究应着眼于更大的种族多样性和数据集中的变量,以提高概括性。
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引用次数: 0
Evaluation methods of pressure injury stages: A systematic review and meta-analysis 压力损伤阶段的评价方法:系统回顾和荟萃分析
IF 2.4 3区 医学 Q2 DERMATOLOGY Pub Date : 2025-03-21 DOI: 10.1016/j.jtv.2025.100894
Qianwen Chao , Juhong Pei , Yuting Wei , Zhuang Yang , Xiaorui Wang , Li Du , Lin Han

Background

Pressure injury is prevalent in clinical settings and demands precise staging for optimal care. Subjectivity and imprecision in traditional visual assessments have sparked the creation of advanced technology-based evaluation tools.

Aims

To systematically assess pressure injury staging methods, analyze their evaluation results, and provide reference for clinical practice.

Design

Systematic review and meta-analysis.

Data sources

PubMed, Embase, Cochrane Library, Web of Science, CINAHL, and manual searches of academic journals and conference proceedings were utilized.

Methods

The study conducted a systematic search of databases in April 2024, utilizing Endnote X9 to document findings. Two reviewers independently extracted data and evaluated its quality using the QUADAS-2 tool. The meta-analysis, conducted in Meta-disc, focused on metrics such as AUC, sensitivity, and specificity. Heterogeneity among the studies was assessed using Cochran's Q and I2 tests.

Results

This review screened 15312 articles and ultimately included 15 studies. These studies described methods for pressure injury staging, including visual assessment, 29 machine learning models, and human-model integrated evaluation. The accuracy of traditional visual assessment was relatively low and showed significant variability. Eight studies involving 24 machine learning models were included in the meta-analysis, demonstrating significantly high accuracy, with an AUC of 0.93, and the combined sensitivity, specificity, and diagnostic odds ratio were 0.81, 0.87, and 20.48, respectively.

Conclusion

The review underscores the advantages of machine learning in diagnosing pressure injuries, offering higher accuracy over traditional methods. Integrating clinical expertise with machine learning enhances medical service quality and efficiency.

Prospero registration number

CRD42023462951.

Prospero registration link

crd.york.ac.uk/prospero/display_record.php?ID=CRD42023462951.
背景:压力性损伤在临床环境中很普遍,需要精确的分期以获得最佳护理。传统视觉评估的主观性和不精确性引发了基于先进技术的评估工具的创造。目的系统评价压伤分期方法,分析其评价结果,为临床实践提供参考。设计系统回顾和荟萃分析。数据来源:pubmed, Embase, Cochrane Library, Web of Science, CINAHL,手工检索学术期刊和会议记录。方法本研究于2024年4月对数据库进行系统检索,利用Endnote X9记录研究结果。两名审稿人独立提取数据并使用QUADAS-2工具评估其质量。Meta-disc上进行的荟萃分析侧重于AUC、敏感性和特异性等指标。采用Cochran’s Q和I2检验评估研究间的异质性。本综述筛选了15312篇文章,最终纳入了15项研究。这些研究描述了压力损伤分期的方法,包括视觉评估、29个机器学习模型和人类模型综合评估。传统的目视评估准确率较低,且存在显著的变异性。meta分析纳入了8项研究,涉及24个机器学习模型,显示出非常高的准确性,AUC为0.93,综合敏感性、特异性和诊断优势比分别为0.81、0.87和20.48。结论本综述强调了机器学习在诊断压力性损伤方面的优势,与传统方法相比,机器学习具有更高的准确性。将临床专业知识与机器学习相结合,可以提高医疗服务质量和效率。普洛斯彼罗注册号crd42023462951。普洛斯彼罗注册linkcrd.york.ac.uk/prospero/display_record.php?ID=CRD42023462951。
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引用次数: 0
Effectiveness of plant and animal-based interventions in preventing and reducing pressure injuries: A systematic review and meta-analysis 植物和动物为基础的干预措施在预防和减少压力伤害的有效性:系统回顾和荟萃分析
IF 2.4 3区 医学 Q2 DERMATOLOGY Pub Date : 2025-03-21 DOI: 10.1016/j.jtv.2025.100893
Esra Özkan , Burçak Şahin Köze , Meryem Yavuz van Giersbergen

Background

Pressure injuries (PIs) are a significant concern among the elderly and bedridden patients, often resulting from prolonged pressure on the skin. Various interventions, including plant and animal-based therapies, are used to prevent and treat PIs. However, there is a lack of comprehensive understanding of the effectiveness of these natural interventions.

Aim

This study aims to systematically review and conduct a meta-analysis of studies using plant and animal-based interventions to prevent and treat pressure injuries.

Methods

A systematic review and meta-analysis were performed according to the PRISMA guidelines. Searches were conducted in PubMed, Web of Science, SCOPUS, and Cochrane databases using keywords related to pressure injuries and natural interventions. Studies published between 2003 and 2023 were included. The inclusion criteria were experimental, quasi-experimental, and case-control studies. Data extraction and quality assessment were performed independently by two researchers. The effect size was calculated using Hedges' g, and heterogeneity was assessed using Cochrane Q and I2 tests.

Results

A total of 13,563 records were identified, with 20 studies meeting the inclusion criteria after screening and full-text review. The total sample size was 2541 participants. The meta-analysis revealed a significant overall effect size (g = −0.614, 95 % CI: −0.890 to −0.337) indicating moderate effectiveness of plant and animal-based interventions in preventing and reducing PIs. Aloe vera, olive oil, and fish oil showed significant effects with p-values <0.05. High heterogeneity was observed among the studies (Q = 91.007, p < 0.05; I2 = 79.123 %), leading to the use of a random effects model.

Conclusions

Plant and animal-based interventions are moderately effective in preventing and reducing pressure injuries. These findings support the integration of natural therapies into clinical practice for PI management. Further research is needed to standardize protocols and explore the long-term effects of these interventions.
压力性损伤(PIs)是老年人和卧床不起的患者非常关注的问题,通常是由于皮肤长期受压造成的。各种干预措施,包括以植物和动物为基础的疗法,用于预防和治疗pi。然而,人们对这些自然干预措施的有效性缺乏全面的了解。目的对植物和动物干预预防和治疗压力性损伤的研究进行系统回顾和荟萃分析。方法根据PRISMA指南进行系统评价和meta分析。在PubMed、Web of Science、SCOPUS和Cochrane数据库中使用与压力损伤和自然干预相关的关键词进行检索。2003年至2023年间发表的研究也被纳入其中。纳入标准为实验性、准实验性和病例对照研究。数据提取和质量评估由两名研究人员独立完成。效应量采用Hedges' g计算,异质性采用Cochrane Q和I2检验评估。结果经筛选和全文审阅,共纳入文献13563篇,符合纳入标准的文献20篇。总样本量为2541名参与者。荟萃分析显示,总体效应值显著(g = - 0.614, 95% CI: - 0.890至- 0.337),表明植物和动物干预措施在预防和减少pi方面效果中等。芦荟、橄榄油和鱼油的影响显著,p值为0.05。研究间存在高度异质性(Q = 91.007, p <;0.05;I2 = 79.123 %),导致使用随机效应模型。结论以植物和动物为基础的干预措施对预防和减少压力性损伤具有中等效果。这些发现支持将自然疗法整合到PI管理的临床实践中。需要进一步的研究来规范方案并探索这些干预措施的长期影响。
{"title":"Effectiveness of plant and animal-based interventions in preventing and reducing pressure injuries: A systematic review and meta-analysis","authors":"Esra Özkan ,&nbsp;Burçak Şahin Köze ,&nbsp;Meryem Yavuz van Giersbergen","doi":"10.1016/j.jtv.2025.100893","DOIUrl":"10.1016/j.jtv.2025.100893","url":null,"abstract":"<div><h3>Background</h3><div>Pressure injuries (PIs) are a significant concern among the elderly and bedridden patients, often resulting from prolonged pressure on the skin. Various interventions, including plant and animal-based therapies, are used to prevent and treat PIs. However, there is a lack of comprehensive understanding of the effectiveness of these natural interventions.</div></div><div><h3>Aim</h3><div>This study aims to systematically review and conduct a meta-analysis of studies using plant and animal-based interventions to prevent and treat pressure injuries.</div></div><div><h3>Methods</h3><div>A systematic review and meta-analysis were performed according to the PRISMA guidelines. Searches were conducted in PubMed, Web of Science, SCOPUS, and Cochrane databases using keywords related to pressure injuries and natural interventions. Studies published between 2003 and 2023 were included. The inclusion criteria were experimental, quasi-experimental, and case-control studies. Data extraction and quality assessment were performed independently by two researchers. The effect size was calculated using Hedges' g, and heterogeneity was assessed using Cochrane Q and I<sup>2</sup> tests.</div></div><div><h3>Results</h3><div>A total of 13,563 records were identified, with 20 studies meeting the inclusion criteria after screening and full-text review. The total sample size was 2541 participants. The meta-analysis revealed a significant overall effect size (g = −0.614, 95 % CI: −0.890 to −0.337) indicating moderate effectiveness of plant and animal-based interventions in preventing and reducing PIs. Aloe vera, olive oil, and fish oil showed significant effects with p-values &lt;0.05. High heterogeneity was observed among the studies (Q = 91.007, p &lt; 0.05; I<sup>2</sup> = 79.123 %), leading to the use of a random effects model.</div></div><div><h3>Conclusions</h3><div>Plant and animal-based interventions are moderately effective in preventing and reducing pressure injuries. These findings support the integration of natural therapies into clinical practice for PI management. Further research is needed to standardize protocols and explore the long-term effects of these interventions.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 3","pages":"Article 100893"},"PeriodicalIF":2.4,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143715553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesising the evidence for patient and public involvement in pressure ulcer research: A scoping review protocol 综合患者和公众参与压疮研究的证据:范围审查方案
IF 2.4 3区 医学 Q2 DERMATOLOGY Pub Date : 2025-03-19 DOI: 10.1016/j.jtv.2025.100892
Hannah Wilson , Aglecia Moda Vitoriano Budri , Liane Araujo Teixeira , Pinar Avsar , Linda Nugent , Niamh Dillon , Declan Naughton , Wendy Chaboyer , Tom O'Connor , Killian Walsh , Sharon Latimer , Zena Moore

Introduction

There is a growing shift toward greater inclusion of patients and the public in the design, conduct, and implementation of research to ensure it is more meaningful, relevant and impactful. This involvement creates a partnership in which patients and the public contribute to decisions throughout the research lifecycle. While the impact and importance of patient and public involvement (PPI) in research is becoming increasingly recognised, the extent of PPI in pressure ulcer (PU) research has yet to be fully established. This scoping review aims to provide insights into how PPI has been included and reported in PU research, ultimately placing a spotlight on the impact and importance of reporting PPI to guide future PU research.

Methods and analysis

Through synthesising literature from a diverse global landscape, this scoping review aims to achieve the following objectives (1) To explore and map the stage(s) of the PU research cycle where PPI has been incorporated (2) To identify and describe the range of participatory methods, including frameworks, guidelines, or tools, that have been used to facilitate the involvement of patients and the public in PU research. (3) To identify and synthesise reporting impacts of including PPI in PU research, and (4) To map and analyse the terminology commonly used to describe PPI in PU research.
The Joanna Briggs Institute scoping review methodology and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping reviews framework will guide the conduct and reporting of this review. Nine databases will be included in the search strategy and all articles will be independently screened for eligibility by two authors. Data from eligible articles will be extracted using a pre-defined data extraction table, and the results will be analysed and synthesised using the PAGER (Patterns, Advances, Gaps, Evidence for practice and Research recommendations) framework.

Ethics and dissemination

Ethics approval will not be required considering the nature of this scoping review. PPI advisory partners will be consulted for disseminating the results in a format that is accessible and understood by a layperson, in order to communicate the findings to a wide audience and diverse communities. This scoping review will be published in a peer reviewed journal and results will be disseminated at local national and international conferences.

Registration

This scoping review is registered on the Open Science Framework (https://doi.org/10.17605/OSF.IO/JHT34). As is typical with scoping reviews, this protocol may evolve over time. Any updates will be documented on the Open Science Framework platform, along with a clear rationale for the changes.
在研究的设计、实施和实施过程中,越来越多的患者和公众参与进来,以确保研究更有意义、更相关、更有影响力。这种参与创造了一种伙伴关系,患者和公众在整个研究生命周期中为决策做出贡献。虽然患者和公众参与(PPI)在研究中的影响和重要性日益得到认可,但PPI在压疮(PU)研究中的程度尚未完全确定。本综述旨在深入了解PPI在PU研究中是如何被纳入和报告的,最终将重点放在报告PPI的影响和重要性上,以指导未来的PU研究。方法和分析通过综合来自不同全球景观的文献,本范围综述旨在实现以下目标:(1)探索和绘制纳入PPI的PU研究周期的阶段(2)确定和描述用于促进患者和公众参与PU研究的参与性方法的范围,包括框架,指南或工具。(3)识别和综合将PPI纳入PU研究的报告影响,以及(4)绘制和分析用于描述PU研究中PPI的常用术语。乔安娜布里格斯研究所的范围审查方法以及范围审查框架的系统审查和元分析扩展的首选报告项目将指导本审查的实施和报告。9个数据库将被纳入搜索策略,所有文章将由两位作者独立筛选是否合格。将使用预定义的数据提取表从符合条件的文章中提取数据,并使用PAGER(模式、进展、差距、实践证据和研究建议)框架对结果进行分析和综合。伦理和传播考虑到此范围审查的性质,不需要伦理批准。为了将调查结果传达给广泛的受众和不同的社区,将与PPI咨询合作伙伴协商,以一种外行人可以获得和理解的格式传播结果。这项范围审查将发表在同行评议的期刊上,结果将在地方、国家和国际会议上传播。此范围审查已在开放科学框架(https://doi.org/10.17605/OSF.IO/JHT34)上注册。正如典型的范围界定审查一样,该协议可能会随着时间的推移而发展。任何更新都将在开放科学框架平台上进行记录,并提供明确的更改理由。
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引用次数: 0
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Journal of tissue viability
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