Journal of tissue viability最新文献_第10页

Silicone adhesive multilayer foam dressings to prevent hospital-acquired sacrum pressure ulcers: An economic evaluation based on a publicly funded pragmatic randomized controlled trial linked with real-world data 硅酮粘合多层泡沫敷料可预防医院获得性骶骨压疮：基于公共资助的实用随机对照试验与真实世界数据的经济评估。

IF 2.4 3区医学 Q2 DERMATOLOGY

Journal of tissue viability

Pub Date : 2024-11-01 DOI: 10.1016/j.jtv.2024.08.011

Mattias Neyt , Christophe De Meester , Stephan Devriese , Elisabeth Marynen , Dimitri Beeckman

Objectives

To estimate the cost-effectiveness of sacrum multilayer silicone foam dressings as an adjuvant prophylactic therapy compared to standard pressure ulcer prevention in a hospital population at high risk for pressure ulcer development.

Methods

An economic evaluation is performed from a healthcare payer's perspective. This evaluation is based on a Belgian publicly funded pragmatic randomized controlled trial (RCT), linked with real-world data from administrative claims database and a Belgian cost analysis. A cost-consequences analysis with a one-year time horizon is performed.

Results

The RCT has shown that the risk of developing a new pressure ulcer on the sacrum was statistically significantly reduced by 41 % in the treatment group (RR = 0.59, 95 % CI 0.35–0.98, p = 0.04). The absolute risk reduction of 2.0 % (95 % CI -0.1–4.1 %) coincides with a number needed to treat of 50.0 to prevent one new pressure ulcer of category II or worse. The evolution of quality of life is on average negative for patients who developed a pressure ulcer before day 3, while it is positive for patients without pressure ulcers. In a scenario with conservative assumptions, i.e. without inclusion of price discounts for the multilayer silicone foam dressings and only including costs during the hospitalization, pressure ulcer prevention with dressings on the sacrum was already cost-neutral.

Conclusions

The preventive use of silicone adhesive multilayer foam dressings on the sacrum for a population similar to the pragmatic trial population can be supported both from a clinical and economic point of view.

目的估算骶骨多层硅酮泡沫敷料作为辅助预防疗法与标准压疮预防疗法相比，在医院压疮高危人群中的成本效益。方法从医疗支付方的角度进行经济评估。该评估以比利时一项由政府资助的实用随机对照试验（RCT）为基础，并与行政索赔数据库中的实际数据和比利时成本分析相结合。结果随机对照试验表明，在治疗组中，骶骨发生新褥疮的风险在统计学上显著降低了 41%（RR = 0.59，95 % CI 0.35-0.98，p = 0.04）。绝对风险降低了 2.0 % (95 % CI -0.1-4.1 %)，这与预防一个新的 II 类或更严重压疮所需的治疗次数 50.0 相吻合。第 3 天前出现压疮的患者的生活质量平均为负值，而未出现压疮的患者的生活质量则为正值。在保守假设的情况下，即不包括多层硅酮泡沫敷料的价格折扣，也不包括住院期间的费用，使用骶骨敷料预防压疮已经不增加成本。

{"title":"Silicone adhesive multilayer foam dressings to prevent hospital-acquired sacrum pressure ulcers: An economic evaluation based on a publicly funded pragmatic randomized controlled trial linked with real-world data","authors":"Mattias Neyt , Christophe De Meester , Stephan Devriese , Elisabeth Marynen , Dimitri Beeckman","doi":"10.1016/j.jtv.2024.08.011","DOIUrl":"10.1016/j.jtv.2024.08.011","url":null,"abstract":"<div><h3>Objectives</h3><div>To estimate the cost-effectiveness of sacrum multilayer silicone foam dressings as an adjuvant prophylactic therapy compared to standard pressure ulcer prevention in a hospital population at high risk for pressure ulcer development.</div></div><div><h3>Methods</h3><div>An economic evaluation is performed from a healthcare payer's perspective. This evaluation is based on a Belgian publicly funded pragmatic randomized controlled trial (RCT), linked with real-world data from administrative claims database and a Belgian cost analysis. A cost-consequences analysis with a one-year time horizon is performed.</div></div><div><h3>Results</h3><div>The RCT has shown that the risk of developing a new pressure ulcer on the sacrum was statistically significantly reduced by 41 % in the treatment group (RR = 0.59, 95 % CI 0.35–0.98, p = 0.04). The absolute risk reduction of 2.0 % (95 % CI -0.1–4.1 %) coincides with a number needed to treat of 50.0 to prevent one new pressure ulcer of category II or worse. The evolution of quality of life is on average negative for patients who developed a pressure ulcer before day 3, while it is positive for patients without pressure ulcers. In a scenario with conservative assumptions, i.e. without inclusion of price discounts for the multilayer silicone foam dressings and only including costs during the hospitalization, pressure ulcer prevention with dressings on the sacrum was already cost-neutral.</div></div><div><h3>Conclusions</h3><div>The preventive use of silicone adhesive multilayer foam dressings on the sacrum for a population similar to the pragmatic trial population can be supported both from a clinical and economic point of view.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"33 4","pages":"Pages 772-777"},"PeriodicalIF":2.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142186013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How does the training given to intensive care nurses affect their attitudes toward preventing pressure ulcers? 对重症监护护士的培训如何影响她们对预防压疮的态度？

IF 2.4 3区医学 Q2 DERMATOLOGY

Journal of tissue viability

Pub Date : 2024-11-01 DOI: 10.1016/j.jtv.2024.10.004

Handan Topan , Özlem Ceyhan , Meral Başaran

Objective

The study aimed to determine the effect of training in the prevention/treatment of pressure ulcers on nurses' attitudes.

Material method

The study was conducted experimentally in a pretest-posttest design. Training was given to nurses participating in the study with content prepared by "Wound and Ostomy Incontinence Nurses Association" guide. The study was conducted between August and October with nurses working in Level 3 intensive care units. The study was completed with 79 nurses. Before the training was given, the "Nurse Introduction Form" and " Attitude Towards Pressure Ulcer Prevention Instrument (ATPUPI)" form were applied to those. All nurses were re-administered the ATPUPI scale three months after the training to evaluate their attitudes. Frequency analysis, descriptive statistics, one-way ANOVA, and independent sample tests were used in statistical analyses.

Results

The mean age of the nurses was 29.62 ± 5.74 years, the mean length of service was 71.77 ± 77.19 months, 94.9 % were graduates, and 82.3 % worked in shifts. The mean scores before the training were 44.53 ± 4.13 and 45.12 ± 2.53 after the training. It was determined that there was a significant difference between the nurses who did not receive training on pressure ulcers other than undergraduate education and those who obtained training in terms of the mean score of ATPUPI. Still, after the training, the mean scores reached a similar level, and this difference disappeared. The increase in the mean scores of those who did not receive any education other than undergraduate education was found to be statistically significant.

Conclusion

As a result of our study, intensive care nurses' attitudes toward preventing pressure ulcers were found to be at a high level. It was found that the training given to nurses who had not received training on pressure ulcers other than undergraduate education had a significant positive effect on their attitudes. According to this result, it is recommended that in-service training should be given from the moment they start intensive care and repeated at regular intervals to ensure continuity in knowledge, attitude, and care behavior.

目的：本研究旨在确定预防/治疗压疮培训对护士态度的影响：研究旨在确定预防/治疗压疮培训对护士态度的影响：材料方法：本研究采用实验性的前测-后测设计。对参与研究的护士进行了培训，培训内容由 "伤口和造口失禁护士协会 "指南编写。研究于 8 月至 10 月间进行，对象是在三级重症监护病房工作的护士。共有 79 名护士完成了这项研究。在培训之前，对这些护士进行了 "护士介绍表 "和 "预防褥疮态度问卷（ATPUPI）"。培训结束三个月后，所有护士再次接受 ATPUPI 量表，以评估其态度。统计分析采用了频率分析、描述性统计、单因素方差分析和独立样本检验：护士的平均年龄为（29.62±5.74）岁，平均工龄为（71.77±77.19）个月，94.9%为毕业生，82.3%轮班工作。培训前的平均得分是（44.53 ± 4.13）分，培训后的平均得分是（45.12 ± 2.53）分。结果表明，除本科教育外未接受过压疮培训的护士与接受过培训的护士在 ATPUPI 平均得分上存在显著差异。但在培训后，平均得分达到了相似的水平，这种差异消失了。除本科教育外，未接受任何其他教育者的平均得分的提高在统计学上有显著意义：我们的研究结果表明，重症监护护士对预防压疮的态度处于较高水平。研究发现，对那些除本科教育外未接受过任何有关压疮培训的护士进行培训，对其态度有明显的积极影响。根据这一结果，建议从开始重症监护的那一刻起就进行在职培训，并定期重复培训，以确保知识、态度和护理行为的连续性。

{"title":"How does the training given to intensive care nurses affect their attitudes toward preventing pressure ulcers?","authors":"Handan Topan , Özlem Ceyhan , Meral Başaran","doi":"10.1016/j.jtv.2024.10.004","DOIUrl":"10.1016/j.jtv.2024.10.004","url":null,"abstract":"<div><h3>Objective</h3><div>The study aimed to determine the effect of training in the prevention/treatment of pressure ulcers on nurses' attitudes.</div></div><div><h3>Material method</h3><div>The study was conducted experimentally in a pretest-posttest design. Training was given to nurses participating in the study with content prepared by \"Wound and Ostomy Incontinence Nurses Association\" guide. The study was conducted between August and October with nurses working in Level 3 intensive care units. The study was completed with 79 nurses. Before the training was given, the \"Nurse Introduction Form\" and \" Attitude Towards Pressure Ulcer Prevention Instrument (ATPUPI)\" form were applied to those. All nurses were re-administered the ATPUPI scale three months after the training to evaluate their attitudes. Frequency analysis, descriptive statistics, one-way ANOVA, and independent sample tests were used in statistical analyses.</div></div><div><h3>Results</h3><div>Th<strong>e</strong> mean age of the nurses was 29.62 ± 5.74 years, the mean length of service was 71.77 ± 77.19 months, 94.9 % were graduates, and 82.3 % worked in shifts. The mean scores before the training were 44.53 ± 4.13 and 45.12 ± 2.53 after the training. It was determined that there was a significant difference between the nurses who did not receive training on pressure ulcers other than undergraduate education and those who obtained training in terms of the mean score of ATPUPI. Still, after the training, the mean scores reached a similar level, and this difference disappeared. The increase in the mean scores of those who did not receive any education other than undergraduate education was found to be statistically significant.</div></div><div><h3>Conclusion</h3><div>As a result of our study, intensive care nurses' attitudes toward preventing pressure ulcers were found to be at a high level. It was found that the training given to nurses who had not received training on pressure ulcers other than undergraduate education had a significant positive effect on their attitudes. According to this result, it is recommended that in-service training should be given from the moment they start intensive care and repeated at regular intervals to ensure continuity in knowledge, attitude, and care behavior.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"33 4","pages":"Pages 802-807"},"PeriodicalIF":2.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142468706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the relationship between pressure ulcer knowledge and self-efficiency among nursing students: A multicenter study 探索护理专业学生压疮知识与自我效能之间的关系：一项多中心研究。

IF 2.4 3区医学 Q2 DERMATOLOGY

Journal of tissue viability

Pub Date : 2024-11-01 DOI: 10.1016/j.jtv.2024.06.017

Aysun Bayram , Yasemin Şara , Füsun Uzgör , Havva Öztürk

Aim

To determine the relationship between the knowledge and self-efficiency regarding pressure ulcers of nursing students.

Methods

This descriptive and correlational study was conducted with 775 nursing students from three different universities in various regions of Turkey. The “Pressure Ulcer Knowledge Assessment Tool-Updated Version” and “Pressure Ulcer Management Self‐Efficiency Scale for Nurses” tool were used to collect data between May and September 2023. The Strengthening the Reporting of Observational Studies checklist was followed to report this study.

Results

The mean knowledge score was 7.27 ± 3.09, and the mean self-efficiency on pressure ulcer management score was 35.5 ± 18.3. A statistically significant positive correlation was found between nursing students' knowledge and self-efficiency mean scores regarding pressure ulcers (p < 0.05). A significant difference was also found between the students’ academic levels and gender and their knowledge and self-efficiency scores regarding pressure ulcers.

Conclusion

In this study, where the data covers these three institutions, students' pressure ulcer knowledge and self-efficiency scores were lower compared to all academic years. Accordingly, it was also determined that students with more nursing practice experience showed higher knowledge and self-efficacy scores than students with less nursing practice experience. Additionally, the students' self-efficacy increased along with their knowledge level. Training courses may be suggested to improve students’ knowledge and self-efficiency regarding pressure ulcers.

目的：确定护理专业学生有关压疮的知识和自我效能之间的关系：这项描述性和相关性研究的对象是来自土耳其不同地区三所不同大学的 775 名护理专业学生。采用 "压疮知识评估工具--更新版 "和 "护士压疮管理自我效能量表 "工具收集 2023 年 5 月至 9 月期间的数据。研究报告采用了 "加强观察性研究报告核对表"：平均知识得分（7.27±3.09）分，平均压疮管理自我效能得分（35.5±18.3）分。在统计学上发现，护生在压疮方面的知识和自我效能平均得分之间存在明显的正相关性（p 结论：护生在压疮方面的知识和自我效能平均得分之间存在明显的正相关性：在本研究中，数据涵盖了这三所院校，与所有学年相比，学生的压疮知识和自我效能得分较低。相应地，研究还发现，护理实践经验丰富的学生比护理实践经验较少的学生显示出更高的知识和自我效能得分。此外，学生的自我效能感也随着知识水平的提高而提高。建议开设培训课程，以提高学生对压疮的认识和自我效能。

{"title":"Exploring the relationship between pressure ulcer knowledge and self-efficiency among nursing students: A multicenter study","authors":"Aysun Bayram , Yasemin Şara , Füsun Uzgör , Havva Öztürk","doi":"10.1016/j.jtv.2024.06.017","DOIUrl":"10.1016/j.jtv.2024.06.017","url":null,"abstract":"<div><h3>Aim</h3><div>To determine the relationship between the knowledge and self-efficiency regarding pressure ulcers of nursing students.</div></div><div><h3>Methods</h3><div>This descriptive and correlational study was conducted with 775 nursing students from three different universities in various regions of Turkey. The “Pressure Ulcer Knowledge Assessment Tool-Updated Version” and “Pressure Ulcer Management<span> Self‐Efficiency Scale for Nurses” tool were used to collect data between May and September 2023. The Strengthening the Reporting of Observational Studies checklist was followed to report this study.</span></div></div><div><h3>Results</h3><div>The mean knowledge score was 7.27 <strong>±</strong> 3.09, and the mean self-efficiency on pressure ulcer management score was 35.5 ± 18.3. A statistically significant positive correlation was found between nursing students' knowledge and self-efficiency mean scores regarding pressure ulcers (p < 0.05). A significant difference was also found between the students’ academic levels and gender and their knowledge and self-efficiency scores regarding pressure ulcers.</div></div><div><h3>Conclusion</h3><div>In this study, where the data covers these three institutions, students' pressure ulcer knowledge and self-efficiency scores were lower compared to all academic years. Accordingly, it was also determined that students with more nursing practice experience showed higher knowledge and self-efficacy scores than students with less nursing practice experience. Additionally, the students' self-efficacy increased along with their knowledge level. Training courses may be suggested to improve students’ knowledge and self-efficiency regarding pressure ulcers.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"33 4","pages":"Pages 681-687"},"PeriodicalIF":2.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141476859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Women's skin care behaviors: How to influence sunscreen use 女性的皮肤护理行为：如何影响防晒霜的使用。

IF 2.4 3区医学 Q2 DERMATOLOGY

Journal of tissue viability

Pub Date : 2024-11-01 DOI: 10.1016/j.jtv.2024.06.015

Tian Chen , Chao Yuan , Mengzhen Zhao

Background

It is well known that women have been plagued by various skin problems. However, research on the characteristics of women's skin at different ages is still inadequate. In addition, there is a lack of research on the extent of women's skincare habits and skin care awareness.

Methods

A cross-sectional survey on skin was carried out in Shanghai, China, which was conducted by means of a questionnaire. 3678 women, aged 18–59 years, participated in the study. The information collected focused on the importance they place on their skin, the skin problems they have, and their use and perception of skin care products.

Results

Before the age of 25, the most common skin problems that women face are dryness and oiliness, while after the age of 30, skin-ageing issues begin to appear and worsen with age. In addition, the higher the level of education, the higher the frequency of and compliance with sunscreen use, and the economy also affects women's use of sunscreen. Importantly, the importance women place on their skin and the level of sunscreen awareness affects women's use of sunscreen.

Conclusions

This study was conducted to understand the skin characteristics of women of different age groups as well as to determine the factors that influence the use of sunscreens, which will not only promote women's skin care practices and product development, but also provide important clues for future activities on sunscreen use and health promotion.

背景：众所周知，女性一直受到各种皮肤问题的困扰。然而，对不同年龄段女性皮肤特征的研究仍然不足。此外，对女性的护肤习惯和护肤意识也缺乏研究：方法：在中国上海开展了一项皮肤横断面调查，采用问卷调查的方式。3678 名年龄在 18-59 岁之间的女性参与了调查。所收集的信息主要涉及她们对皮肤的重视程度、存在的皮肤问题以及对护肤品的使用和看法：结果：25 岁以前，女性最常见的皮肤问题是干燥和出油，而 30 岁以后，皮肤老化问题开始出现，并随着年龄的增长而加剧。此外，受教育程度越高，使用防晒霜的频率和依从性就越高，经济状况也会影响女性对防晒霜的使用。重要的是，女性对自己皮肤的重视程度和防晒意识水平也会影响女性对防晒霜的使用：本研究旨在了解不同年龄段女性的皮肤特征，并确定影响防晒霜使用的因素，这不仅能促进女性的皮肤护理实践和产品开发，还能为今后的防晒霜使用和健康促进活动提供重要线索。

{"title":"Women's skin care behaviors: How to influence sunscreen use","authors":"Tian Chen , Chao Yuan , Mengzhen Zhao","doi":"10.1016/j.jtv.2024.06.015","DOIUrl":"10.1016/j.jtv.2024.06.015","url":null,"abstract":"<div><h3>Background</h3><div>It is well known that women have been plagued by various skin problems. However, research on the characteristics of women's skin at different ages is still inadequate. In addition, there is a lack of research on the extent of women's skincare habits and skin care awareness.</div></div><div><h3>Methods</h3><div>A cross-sectional survey on skin was carried out in Shanghai, China, which was conducted by means of a questionnaire. 3678 women, aged 18–59 years, participated in the study. The information collected focused on the importance they place on their skin, the skin problems they have, and their use and perception of skin care products.</div></div><div><h3>Results</h3><div>Before the age of 25, the most common skin problems that women face are dryness and oiliness, while after the age of 30, skin-ageing issues begin to appear and worsen with age. In addition, the higher the level of education, the higher the frequency of and compliance with sunscreen<span> use, and the economy also affects women's use of sunscreen. Importantly, the importance women place on their skin and the level of sunscreen awareness affects women's use of sunscreen.</span></div></div><div><h3>Conclusions</h3><div>This study was conducted to understand the skin characteristics of women of different age groups as well as to determine the factors that influence the use of sunscreens, which will not only promote women's skin care practices and product development, but also provide important clues for future activities on sunscreen use and health promotion.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"33 4","pages":"Pages 840-845"},"PeriodicalIF":2.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141476861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A study of social isolation in patients with varicose veins of the lower extremities: A scoping review 下肢静脉曲张患者的社会隔离研究：范围综述。

IF 2.4 3区医学 Q2 DERMATOLOGY

Journal of tissue viability

Pub Date : 2024-11-01 DOI: 10.1016/j.jtv.2024.09.012

Yunjiao Wang , Rui Li , Liping Bai , Zhuanfang Zou , Chunyan Zheng , Feijin Peng , Shuzhen Wang , Yujin Yang

Objectives

To undertake a scoping review of the literature on social alienation in patients with lower extremity varicose veins in order to serve as a reference for future studies in the field.

Methods

With a focus on the phenomenon of social alienation in patients with varicose veins of the lower extremities, a systematic search of Chinese and English databases was carried out using the scoping review methodology as a framework. The included literature was summarized and analyzed with a time frame from database construction to June 24, 2024.

Results

A total of 15 publications were included, demonstrating that social alienation is a frequent occurrence in people with varicose veins of the lower extremities but has not yet received much attention. In individuals with varicose veins of the lower limbs, demographic factors, illness issues, psychological problems, and social factors are the key influences on social alienation.

Conclusion

Social alienation is a common phenomenon that is unevenly distributed in patients with varicose veins of the lower leg and is influenced by a number of different circumstances. In order to better meet the social needs of patients, healthcare professionals should pay attention to the issue of social alienation in patients with varicose veins of the lower extremity, identify and implement intervention strategies quickly, and actively explore a new model of treatment and care for social alienation.

目的：对有关下肢静脉曲张患者社会疏离感的文献进行综述，以便为今后的研究提供参考：对有关下肢静脉曲张患者社会疏离现象的文献进行综述，为今后该领域的研究提供参考：方法：以下肢静脉曲张患者的社会疏离现象为研究重点，以范围界定法为框架，对中英文数据库进行了系统检索。对纳入的文献进行了汇总和分析，时间范围从数据库建立到2024年6月24日：结果：共收录了 15 篇文献，表明社交疏离是下肢静脉曲张患者经常出现的问题，但尚未得到广泛关注。在下肢静脉曲张患者中，人口因素、疾病问题、心理问题和社会因素是影响社交疏离的关键因素：社会疏离感是一种常见现象，在小腿静脉曲张患者中分布不均，并受到多种不同情况的影响。为了更好地满足患者的社会需求，医护人员应重视下肢静脉曲张患者的社会疏离问题，尽快确定并实施干预策略，积极探索社会疏离的治疗和护理新模式。

{"title":"A study of social isolation in patients with varicose veins of the lower extremities: A scoping review","authors":"Yunjiao Wang , Rui Li , Liping Bai , Zhuanfang Zou , Chunyan Zheng , Feijin Peng , Shuzhen Wang , Yujin Yang","doi":"10.1016/j.jtv.2024.09.012","DOIUrl":"10.1016/j.jtv.2024.09.012","url":null,"abstract":"<div><h3>Objectives</h3><div>To undertake a scoping review of the literature on social alienation in patients with lower extremity varicose veins in order to serve as a reference for future studies in the field.</div></div><div><h3>Methods</h3><div>With a focus on the phenomenon of social alienation in patients with varicose veins of the lower extremities, a systematic search of Chinese and English databases was carried out using the scoping review methodology as a framework. The included literature was summarized and analyzed with a time frame from database construction to June 24, 2024.</div></div><div><h3>Results</h3><div>A total of 15 publications were included, demonstrating that social alienation is a frequent occurrence in people with varicose veins of the lower extremities but has not yet received much attention. In individuals with varicose veins of the lower limbs, demographic factors, illness issues, psychological problems, and social factors are the key influences on social alienation.</div></div><div><h3>Conclusion</h3><div>Social alienation is a common phenomenon that is unevenly distributed in patients with varicose veins of the lower leg and is influenced by a number of different circumstances. In order to better meet the social needs of patients, healthcare professionals should pay attention to the issue of social alienation in patients with varicose veins of the lower extremity, identify and implement intervention strategies quickly, and actively explore a new model of treatment and care for social alienation.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"33 4","pages":"Pages 930-937"},"PeriodicalIF":2.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of COVID-19 on the care of diabetic foot ulcers: A scoping review COVID-19 对糖尿病足溃疡护理的影响：范围审查。

IF 2.4 3区医学 Q2 DERMATOLOGY

Journal of tissue viability

Pub Date : 2024-11-01 DOI: 10.1016/j.jtv.2024.06.016

Sinead Flynn , Ellen Kirwan , Claire MacGilchrist , Caroline McIntosh

Aim

The aims and objectives of this scoping review were to conduct a systematic search of the literature to identify the nature and extent of the research evidence to which the COVID-19 pandemic impacted and disrupted the care of Diabetic Foot Ulcers (DFU) and the subsequent impact on patient outcomes. Secondly, to identify transformation in models of care and service delivery, adoption of innovative technologies and new models of service innovations, including modalities such as telehealth that were adopted during the pandemic.

Methods

This systematic scoping review was conducted in accordance with the Joanna Briggs Institute methodology for scoping reviews and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping reviews (PRISMA-ScR).

Results

Nineteen papers were included. These studies explored aspects of care for DFUs during the COVID-19 pandemic. The focus of these studies ranged from exploring new modalities of care such as telehealth, reporting of clinical outcomes, development of triage systems and patient behaviors during COVID-19.

Conclusion

Ten of twelve studies reported on DFU outcomes and reported a worsening of outcomes compared to pre-pandemic times. Reduced DFU presentations, alongside an increase in urgent hospitalisations and amputation, were key themes that emerged from this review. More high-quality evidence is needed to establish any longer-lasting effects of the Covid-19 pandemic on people living with DFU. Further, there is a lack of evidence relating to the feasibility and success of telemedicine and limited data on changes to service delivery, including triage systems in this patient cohort.

目的：本范围综述的目的和目标是对文献进行系统检索，以确定 COVID-19 大流行影响和破坏糖尿病足溃疡 (DFU) 护理的研究证据的性质和程度，以及随后对患者预后的影响。其次，确定护理和服务提供模式的转变、创新技术的采用和服务创新的新模式，包括大流行期间采用的远程医疗等模式：本系统性范围界定综述是根据乔安娜-布里格斯研究所（Joanna Briggs Institute）的范围界定综述方法和范围界定综述系统性综述和荟萃分析扩展报告首选项目（PRISMA-ScR）进行的：共纳入 19 篇论文。这些研究探讨了 COVID-19 大流行期间 DFU 护理的各个方面。这些研究的重点包括探索新的护理模式（如远程医疗）、报告临床结果、开发分流系统以及 COVID-19 期间的患者行为：结论：12 项研究中有 10 项报告了 DFU 的治疗结果，与大流行前相比，治疗结果有所恶化。DFU发病率的降低以及紧急住院和截肢率的上升是本次综述的关键主题。要确定 Covid-19 大流行对 DFU 患者的长期影响，还需要更多高质量的证据。此外，有关远程医疗的可行性和成功率的证据还很缺乏，有关服务提供（包括分诊系统）的变化的数据也很有限。

{"title":"The impact of COVID-19 on the care of diabetic foot ulcers: A scoping review","authors":"Sinead Flynn , Ellen Kirwan , Claire MacGilchrist , Caroline McIntosh","doi":"10.1016/j.jtv.2024.06.016","DOIUrl":"10.1016/j.jtv.2024.06.016","url":null,"abstract":"<div><h3>Aim</h3><div>The aims and objectives of this scoping review were to conduct a systematic search of the literature to identify the nature and extent of the research evidence to which the COVID-19 pandemic impacted and disrupted the care of Diabetic Foot Ulcers (DFU) and the subsequent impact on patient outcomes. Secondly, to identify transformation in models of care and service delivery, adoption of innovative technologies and new models of service innovations, including modalities such as telehealth that were adopted during the pandemic.</div></div><div><h3>Methods</h3><div>This systematic scoping review was conducted in accordance with the Joanna Briggs Institute methodology for scoping reviews and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping reviews (PRISMA-ScR).</div></div><div><h3>Results</h3><div>Nineteen papers were included. These studies explored aspects of care for DFUs during the COVID-19 pandemic. The focus of these studies ranged from exploring new modalities of care such as telehealth, reporting of clinical outcomes, development of triage systems and patient behaviors during COVID-19.</div></div><div><h3>Conclusion</h3><div>Ten of twelve studies reported on DFU outcomes and reported a worsening of outcomes compared to pre-pandemic times. Reduced DFU presentations, alongside an increase in urgent hospitalisations and amputation, were key themes that emerged from this review. More high-quality evidence is needed to establish any longer-lasting effects of the Covid-19 pandemic on people living with DFU. Further, there is a lack of evidence relating to the feasibility and success of telemedicine and limited data on changes to service delivery, including triage systems in this patient cohort.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"33 4","pages":"Pages 521-529"},"PeriodicalIF":2.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141563630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterising mobility and pressure exposure in community dwelling residents with pressure ulcers using monitoring technology and intelligent algorithm 利用监测技术和智能算法描述患有褥疮的社区住宅居民的活动能力和压力暴露情况

IF 2.4 3区医学 Q2 DERMATOLOGY

Journal of tissue viability

Pub Date : 2024-11-01 DOI: 10.1016/j.jtv.2024.07.005

Silvia Caggiari , Nicci Aylward-Wotton , Bridie Kent , Peter R. Worsley

Aim

Individuals in the community with reduced mobility are at risk of exposure to prolonged lying and sitting postures, which may cause pressure ulcers. The present study combines continuous pressure monitoring technology and intelligent algorithms to evaluate posture, mobility, and pressure profiles in a cohort of community dwelling patients, who had acquired pressure ulcers.

Materials and methods

This study represents a secondary analysis of the data from the Quality Improvement project ‘Pressure Reduction through COntinuous Monitoring In the community SEtting (PROMISE)’. 22 patients with pressure ulcers were purposely selected from 105 recruited community residents. Data were collected using a commercial continuous pressure monitoring system over a period of 1–4 days, and analysed with an intelligent algorithm using machine learning to determine posture and mobility events. Duration and magnitude of pressure signatures of each static posture and exposure thresholds were identified based on a sigmoid relationship between pressure and time.

Results

Patients revealed a wide range of ages (30–95 years), BMI (17.5–47 kg/m²) and a series of co-morbidities, which may have influenced the susceptibility to skin damage. Posture, mobility, and pressure data revealed a high degree of inter-subject variability. Largest duration of static postures ranged between 1.7 and 19.8 h, with 17/22 patients spending at least 60 % of their monitoring period in static postures which lasted >2 h. Data revealed that many patients spent prolonged periods with potentially harmful interface pressure conditions, including pressure gradients >60 mmHg/cm.

Conclusion

This study combined posture, mobility, and pressure data from a commercial pressure monitoring technology through an intelligent algorithm. The community residents who had acquired a pressure ulcer at the time of monitoring exhibited trends which exposed their skin and subdermal tissues to prolonged high pressures during static postures. These indicators need further validation through prospective clinical trials.

{"title":"Characterising mobility and pressure exposure in community dwelling residents with pressure ulcers using monitoring technology and intelligent algorithm","authors":"Silvia Caggiari , Nicci Aylward-Wotton , Bridie Kent , Peter R. Worsley","doi":"10.1016/j.jtv.2024.07.005","DOIUrl":"10.1016/j.jtv.2024.07.005","url":null,"abstract":"<div><h3>Aim</h3><div>Individuals in the community with reduced mobility are at risk of exposure to prolonged lying and sitting postures, which may cause pressure ulcers. The present study combines continuous pressure monitoring technology and intelligent algorithms to evaluate posture, mobility, and pressure profiles in a cohort of community dwelling patients, who had acquired pressure ulcers.</div></div><div><h3>Materials and methods</h3><div>This study represents a secondary analysis of the data from the Quality Improvement project ‘Pressure Reduction through COntinuous Monitoring In the community SEtting (PROMISE)’. 22 patients with pressure ulcers were purposely selected from 105 recruited community residents. Data were collected using a commercial continuous pressure monitoring system over a period of 1–4 days, and analysed with an intelligent algorithm using machine learning to determine posture and mobility events. Duration and magnitude of pressure signatures of each static posture and exposure thresholds were identified based on a sigmoid relationship between pressure and time.</div></div><div><h3>Results</h3><div>Patients revealed a wide range of ages (30–95 years), BMI (17.5–47 kg/m<sup>2</sup>) and a series of co-morbidities, which may have influenced the susceptibility to skin damage. Posture, mobility, and pressure data revealed a high degree of inter-subject variability. Largest duration of static postures ranged between 1.7 and 19.8 h, with 17/22 patients spending at least 60 % of their monitoring period in static postures which lasted >2 h. Data revealed that many patients spent prolonged periods with potentially harmful interface pressure conditions, including pressure gradients >60 mmHg/cm.</div></div><div><h3>Conclusion</h3><div>This study combined posture, mobility, and pressure data from a commercial pressure monitoring technology through an intelligent algorithm. The community residents who had acquired a pressure ulcer at the time of monitoring exhibited trends which exposed their skin and subdermal tissues to prolonged high pressures during static postures. These indicators need further validation through prospective clinical trials.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"33 4","pages":"Pages 693-700"},"PeriodicalIF":2.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141690525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Can thermography predict diabetic foot ulcer risk in patients with diabetes mellitus? A systematic review 热成像能否预测糖尿病患者的糖尿病足溃疡风险？系统综述。

IF 2.4 3区医学 Q2 DERMATOLOGY

Journal of tissue viability

Pub Date : 2024-11-01 DOI: 10.1016/j.jtv.2024.06.018

Divyeshz Thakku Sivakumar , Bridget Murray , Zena Moore , Declan Patton , Tom O'Connor , Pinar Avsar

Background

There is a growing prevalence of diabetic foot ulcers (DFUs) in patients with diabetes mellitus and the use of thermography has sparked interest in a non-invasive diagnostic method for early DFU risk assessment and management.

Aim

This systematic review aims to assess the use of thermography in predicting diabetic foot ulcer risk in patients with diabetes mellitus.

Methods

A systematic search of publications using MEDLINE, CINAHL, and Cochrane databases was conducted in April 2023, and relevant articles were reviewed. Data was extracted and a narrative synthesis was undertaken. The evidence-based librarianship (EBL) checklist assessed the methodological quality of the studies included. Reviewing these articles to the primary and secondary outcomes of this literature review. The primary outcome focused on the predictive capabilities of thermography for DFU prediction, while the secondary outcome assessed the feasibility, usability, and effectiveness of thermography.

Results

Eight studies were conducted from 1994 to 2021 with an emphasis on the predictability of thermography in predicting DFU risk. All eight studies focused on temperature variations associated with DFU development. Six of the included studies compared the effectiveness of DFU occurrence in diabetic patients and non-DFU use. The overall results showed that employing thermography in DFU prevention might allow for early detection and intervention, offering a non-invasive and effective means to reduce the risk of DFU development and its associated complications in patients with diabetes mellitus.

Conclusion

The systematic review indicates that thermography holds promise for predicting DFU risk, with studies showcasing predictive capabilities and patient benefits. Despite some challenges and limitations, the evidence suggests thermography's value in assessing DFU risk in diabetes patients, warranting further research on device types and locations.

背景：糖尿病足溃疡（DFU）在糖尿病患者中的发病率越来越高，热成像技术的使用引发了人们对一种用于早期DFU风险评估和管理的无创诊断方法的兴趣：方法：2023 年 4 月，使用 MEDLINE、CINAHL 和 Cochrane 数据库对出版物进行了系统检索，并对相关文章进行了综述。提取数据并进行叙述性综合。循证图书馆学（EBL）检查表评估了所纳入研究的方法学质量。通过审查这些文章，得出了本次文献综述的主要和次要结果。主要结果侧重于热成像对 DFU 的预测能力，次要结果则评估热成像的可行性、可用性和有效性：结果：1994 年至 2021 年期间进行了八项研究，重点关注热成像技术在预测 DFU 风险方面的可预测性。所有八项研究都侧重于与 DFU 发展相关的温度变化。其中六项研究比较了糖尿病患者使用 DFU 和不使用 DFU 的效果。总体结果显示，在预防 DFU 的过程中使用热成像技术可实现早期检测和干预，为降低糖尿病患者发生 DFU 及其相关并发症的风险提供了一种非侵入性的有效手段：系统综述表明，热成像技术在预测 DFU 风险方面大有可为，相关研究显示了其预测能力和对患者的益处。尽管存在一些挑战和局限性，但有证据表明热成像技术在评估糖尿病患者的 DFU 风险方面具有价值，因此有必要对设备类型和位置进行进一步研究。

{"title":"Can thermography predict diabetic foot ulcer risk in patients with diabetes mellitus? A systematic review","authors":"Divyeshz Thakku Sivakumar , Bridget Murray , Zena Moore , Declan Patton , Tom O'Connor , Pinar Avsar","doi":"10.1016/j.jtv.2024.06.018","DOIUrl":"10.1016/j.jtv.2024.06.018","url":null,"abstract":"<div><h3>Background</h3><div>There is a growing prevalence of diabetic foot ulcers (DFUs) in patients with diabetes mellitus and the use of thermography has sparked interest in a non-invasive diagnostic method for early DFU risk assessment and management.</div></div><div><h3>Aim</h3><div>This systematic review aims to assess the use of thermography in predicting diabetic foot ulcer risk in patients with diabetes mellitus.</div></div><div><h3>Methods</h3><div>A systematic search of publications using MEDLINE, CINAHL, and Cochrane databases was conducted in April 2023, and relevant articles were reviewed. Data was extracted and a narrative synthesis was undertaken. The evidence-based librarianship (EBL) checklist assessed the methodological quality of the studies included. Reviewing these articles to the primary and secondary outcomes of this literature review. The primary outcome focused on the predictive capabilities of thermography for DFU prediction, while the secondary outcome assessed the feasibility, usability, and effectiveness of thermography.</div></div><div><h3>Results</h3><div>Eight studies were conducted from 1994 to 2021 with an emphasis on the predictability of thermography in predicting DFU risk. All eight studies focused on temperature variations associated with DFU development. Six of the included studies compared the effectiveness of DFU occurrence in diabetic patients and non-DFU use. The overall results showed that employing thermography in DFU prevention might allow for early detection and intervention, offering a non-invasive and effective means to reduce the risk of DFU development and its associated complications in patients with diabetes mellitus.</div></div><div><h3>Conclusion</h3><div>The systematic review indicates that thermography holds promise for predicting DFU risk, with studies showcasing predictive capabilities and patient benefits. Despite some challenges and limitations, the evidence suggests thermography's value in assessing DFU risk in diabetes patients, warranting further research on device types and locations.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"33 4","pages":"Pages 530-541"},"PeriodicalIF":2.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141723816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Challenges to therapeutic footwear usage for foot ulcer prevention among type 2 diabetes patients: A qualitative study 2 型糖尿病患者使用治疗鞋预防足部溃疡所面临的挑战：定性研究

IF 2.4 3区医学 Q2 DERMATOLOGY

Journal of tissue viability

Pub Date : 2024-11-01 DOI: 10.1016/j.jtv.2024.04.011

Wangqiao Zhu , Khanitta Nuntaboot , Jia Liu , Liuxue Lu , Qiuhuan Huang

Objective

Many contemporary designs solely prioritize the therapeutic function of footwear, neglecting other crucial social and environmental considerations. The study aimed to explore challenges to therapeutic footwear usage for foot ulcer prevention.

Methods

A qualitative critical ethnography design was used in this study. Fourteen participants were recruited at the local hospital in Baise City, China. Data were collected through in-depth interview. A thematic analysis approach was conducted for data analyzing.

Results

This study identified two themes: (1) workplace and physical condition, (2) diverse cultural practice. It was worth noting that slipper as a convenient and cheap wearing choice, decreased the usage of therapeutic footwear. The emerging activity of modern square dancing resulted in more requirements for its design. And the symbolic meaning of hard working in barefoot was also challengeable to therapeutic footwear utilization to some extent.

Conclusions

Therapeutic footwear intervention design should not only focus on the therapeutic functionality, but also consider about individuals’ demands towards working environment and physical status, and particular insights regarding culture and social background. We expected these findings could be evidence for improving therapeutic footwear usage in the future.

许多现代设计仅将鞋类的治疗功能放在首位，而忽视了其他重要的社会和环境因素。本研究旨在探讨使用治疗鞋预防足部溃疡所面临的挑战。本研究采用了定性批判人种学设计。在中国百色市当地医院招募了 14 名参与者。通过深度访谈收集数据。数据分析采用主题分析法。本研究确定了两个主题：（1）工作场所和身体状况；（2）多样化的文化习俗。值得注意的是，拖鞋作为一种方便廉价的穿着选择，减少了治疗鞋的使用。现代广场舞活动的兴起对其设计提出了更高的要求。此外，赤足劳作的象征意义也在一定程度上对治疗鞋的使用提出了挑战。治疗鞋的干预设计不应只关注治疗功能，还应考虑个人对工作环境和身体状况的需求，以及对文化和社会背景的特殊见解。我们希望这些研究结果能为今后改善治疗鞋的使用提供依据。

{"title":"Challenges to therapeutic footwear usage for foot ulcer prevention among type 2 diabetes patients: A qualitative study","authors":"Wangqiao Zhu , Khanitta Nuntaboot , Jia Liu , Liuxue Lu , Qiuhuan Huang","doi":"10.1016/j.jtv.2024.04.011","DOIUrl":"10.1016/j.jtv.2024.04.011","url":null,"abstract":"<div><h3>Objective</h3><div>Many contemporary designs solely prioritize the therapeutic function of footwear, neglecting other crucial social and environmental considerations. The study aimed to explore challenges to therapeutic footwear usage for foot ulcer prevention.</div></div><div><h3>Methods</h3><div>A qualitative critical ethnography design was used in this study. Fourteen participants were recruited at the local hospital in Baise City, China. Data were collected through in-depth interview. A thematic analysis approach was conducted for data analyzing.</div></div><div><h3>Results</h3><div>This study identified two themes: (1) workplace and physical condition, (2) diverse cultural practice. It was worth noting that slipper as a convenient and cheap wearing choice, decreased the usage of therapeutic footwear. The emerging activity of modern square dancing resulted in more requirements for its design. And the symbolic meaning of hard working in barefoot was also challengeable to therapeutic footwear utilization to some extent.</div></div><div><h3>Conclusions</h3><div>Therapeutic footwear intervention design should not only focus on the therapeutic functionality, but also consider about individuals’ demands towards working environment and physical status, and particular insights regarding culture and social background. We expected these findings could be evidence for improving therapeutic footwear usage in the future.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"33 4","pages":"Pages 515-520"},"PeriodicalIF":2.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140827019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Systematic review and meta-analysis of the diagnostic accuracy of inflammatory markers for infected diabetic foot ulcer 对糖尿病足溃疡感染炎症标志物诊断准确性的系统回顾和荟萃分析。

IF 2.4 3区医学 Q2 DERMATOLOGY

Journal of tissue viability

Pub Date : 2024-11-01 DOI: 10.1016/j.jtv.2024.09.007

Hua Chen , Shasha Mei , Yu Zhou , Jiezhi Dai

Background

The aim was to evaluate the diagnostic value of ESR, CPR, PCT, and WBC in patients with infected diabetic foot ulcer (DFU).

Methods

The MEDLINE, Embase, BIOSIS, Cochrane databases, and Web of Knowledge databases were searched, without language restriction, to July 2023. Original studies were selected that reported the performance of ESR, CPR, PCT, and WBC in diagnosing infected DFU. To assess the diagnostic value of biomarkers for infected DFU, pooled sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and area under the summary receiver operating characteristic curve (ROC-AUC) were calculated.

Results

Ten studies with 765 patients were identified in our meta-analysis. The pooled sensitivity and specificity of ESR was 0.82 (95 % CI: 0.68–0.91) and 0.83 (95 % CI: 0.69–0.91) respectively. The pooled sensitivity and specificity of CRP was 0.81 (95 % CI: 0.65–0.91) and 0.91 (95 % CI: 0.79–0.96) respectively. The pooled sensitivity and specificity of PCT was 0.76 (95 % CI: 0.65–0.85) and 0.89 (95 % CI: 0.78–0.95) respectively. The pooled sensitivity and specificity of WBC was 0.75 (95 % CI: 0.64–0.83) and 0.79 (95 % CI: 0.67–0.88) respectively. CRP showed the best diagnostic accuracy at distinguishing infected DFU from noninfected DFU with an AUC of 0.93, followed by PCT (AUC of 0.89), ESR (AUC of 0.89), and WBC (AUC of 0.84).

Conclusion

CPR levels had high efficiency in distinguishing infected DFU from noninfected DFU, followed by PCT, ESR and WBC. All of these biomarkers could be helpful for early diagnosis of infected DFU. New biomarkers for improving medical decision in diagnosis of infected DFU are highly desirable.

背景：目的是评估血沉、心率、血细胞计数和白细胞在糖尿病足溃疡患者中的诊断价值：目的：评估感染性糖尿病足溃疡（DFU）患者血沉、心磷脂、PCT和白细胞的诊断价值：方法：在MEDLINE、Embase、BIOSIS、Cochrane数据库和Web of Knowledge数据库中进行检索，语言不限，检索期至2023年7月。筛选出报告了血沉、心磷脂、PCT 和白细胞在诊断感染性 DFU 方面表现的原创性研究。为评估生物标志物对感染性 DFU 的诊断价值，计算了汇总的敏感性、特异性、阳性似然比（PLR）、阴性似然比（NLR）、诊断几率比（DOR）和汇总接收者操作特征曲线下面积（ROC-AUC）：我们的荟萃分析确定了 10 项研究，共 765 名患者。ESR 的集合敏感性和特异性分别为 0.82（95 % CI：0.68-0.91）和 0.83（95 % CI：0.69-0.91）。CRP 的汇总敏感性和特异性分别为 0.81（95 % CI：0.65-0.91）和 0.91（95 % CI：0.79-0.96）。PCT 的汇总敏感性和特异性分别为 0.76（95 % CI：0.65-0.85）和 0.89（95 % CI：0.78-0.95）。白细胞的集合敏感性和特异性分别为 0.75（95 % CI：0.64-0.83）和 0.79（95 % CI：0.67-0.88）。CRP在区分感染性DFU和非感染性DFU方面显示出最佳诊断准确性，AUC为0.93，其次是PCT（AUC为0.89）、ESR（AUC为0.89）和WBC（AUC为0.84）：结论：CPR水平在区分感染性DFU和非感染性DFU方面具有较高的效率，其次是PCT、血沉和白细胞。所有这些生物标志物都有助于感染性 DFU 的早期诊断。我们非常需要新的生物标志物来改进诊断感染性 DFU 的医疗决策。

{"title":"Systematic review and meta-analysis of the diagnostic accuracy of inflammatory markers for infected diabetic foot ulcer","authors":"Hua Chen , Shasha Mei , Yu Zhou , Jiezhi Dai","doi":"10.1016/j.jtv.2024.09.007","DOIUrl":"10.1016/j.jtv.2024.09.007","url":null,"abstract":"<div><h3>Background</h3><div>The aim was to evaluate the diagnostic value of ESR, CPR, PCT, and WBC in patients with infected diabetic foot ulcer (DFU).</div></div><div><h3>Methods</h3><div>The MEDLINE, Embase, BIOSIS, Cochrane databases, and Web of Knowledge databases were searched, without language restriction, to July 2023. Original studies were selected that reported the performance of ESR, CPR, PCT, and WBC in diagnosing infected DFU. To assess the diagnostic value of biomarkers for infected DFU, pooled sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and area under the summary receiver operating characteristic curve (ROC-AUC) were calculated.</div></div><div><h3>Results</h3><div>Ten studies with 765 patients were identified in our meta-analysis. The pooled sensitivity and specificity of ESR was 0.82 (95 % CI: 0.68–0.91) and 0.83 (95 % CI: 0.69–0.91) respectively. The pooled sensitivity and specificity of CRP was 0.81 (95 % CI: 0.65–0.91) and 0.91 (95 % CI: 0.79–0.96) respectively. The pooled sensitivity and specificity of PCT was 0.76 (95 % CI: 0.65–0.85) and 0.89 (95 % CI: 0.78–0.95) respectively. The pooled sensitivity and specificity of WBC was 0.75 (95 % CI: 0.64–0.83) and 0.79 (95 % CI: 0.67–0.88) respectively. CRP showed the best diagnostic accuracy at distinguishing infected DFU from noninfected DFU with an AUC of 0.93, followed by PCT (AUC of 0.89), ESR (AUC of 0.89), and WBC (AUC of 0.84).</div></div><div><h3>Conclusion</h3><div>CPR levels had high efficiency in distinguishing infected DFU from noninfected DFU, followed by PCT, ESR and WBC. All of these biomarkers could be helpful for early diagnosis of infected DFU. New biomarkers for improving medical decision in diagnosis of infected DFU are highly desirable.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"33 4","pages":"Pages 598-607"},"PeriodicalIF":2.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0