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Correlation between a Compliance of Using Double-Gloving Bundle during Endotracheal Intubation and the Surgical Site Infection 气管插管时使用双手套束的依从性与手术部位感染的关系
Q4 Medicine Pub Date : 2023-03-15 DOI: 10.35755/jmedassocthai.2023.03.13804
Background: Surgical site infections (SSI) represent severe postoperative adverse events. Contamination of operating room (OR) environment with oral bacteria and bloodborne pathogens poses an additional risk of infection. Studies have demonstrated that anesthesia providers’ use of double-gloving care bundle reduce operating room contamination as intubator wears two sets of gloves, sheaths the laryngoscope blade after use with endotracheal tube packaging and removes the outer glove after intubation.Materials and Methods: The authors conducted a prospective, single-center quality improvement project to increase anesthesia provider compliance with a double-gloving care bundle between January and December 2019. The primary measure was the percentage of anesthesia providers’ compliance with the double-gloving care bundle as compared to baseline. The secondary measure was the correlation between compliance with the use of the double-gloving bundle and SSIs.Results: The authors assessed 307 surgeries with 280 that had adequate data for analyses. The initial compliance rate was 38% before the quality improvement initiative. There was no change in the median compliance rate following the initiative. There was no difference in demographic data between the compliance and the non-compliance providers. Three patients (1.07%) developed SSIs, one patient in compliance group and two patients in the non-compliance group. There was no correlation between double-glove care bundle compliance and SSIs.Conclusion: The present study quality improvement initiative study did not increase anesthesia providers’ compliance with the double-gloving care bundle. There was no correlation between compliance and SSIs due to small sample size. However, double-gloving and laryngoscope sheathing by anesthesia providers do improve the standard of care and reduce contamination in the operating room setting. We will continue efforts to increase compliance.Keywords: Double-gloving; Laryngoscope sheathing; Surgical site infection; Anesthesia provider; Operating room contamination
背景:手术部位感染(SSI)是严重的术后不良事件。口腔细菌和血源性病原体污染手术室(OR)环境会增加感染风险。有研究表明,麻醉提供者使用双手套护理包减少了手术室污染,因为插管者戴两套手套,使用后用气管插管包装将喉镜刀片包裹起来,插管后取下外层手套。材料和方法:作者在2019年1月至12月期间进行了一项前瞻性、单中心质量改进项目,以提高麻醉提供者对双手套护理包的依从性。与基线相比,主要测量是麻醉提供者对双手套护理包的依从性百分比。第二项测量是双手套束使用依从性与ssi之间的相关性。结果:作者评估了307例手术,其中280例有足够的数据可供分析。在质量改进开始之前,最初的符合率为38%。在主动性之后,中位数依从率没有变化。依从性和非依从性提供者之间的人口统计数据没有差异。3例(1.07%)发生ssi,依从组1例,不依从组2例。双手套护理包依从性与ssi之间没有相关性。结论:本研究质量改进倡议研究并没有增加麻醉提供者对双手套护理包的依从性。由于样本量小,依从性与ssi之间没有相关性。然而,麻醉提供者的双手套和喉镜护套确实提高了护理标准并减少了手术室环境中的污染。我们将继续加强合规工作。关键词:Double-gloving;喉镜衬板;手术部位感染;麻醉提供者;手术室污染
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引用次数: 0
Looking at mHealth Digital Application Interventions for youths with Addictive Behavior through the Lens of Beck’s Cognitive Model and Cognitive Behavioral Therapy: A Scoping Review 从贝克的认知模型和认知行为疗法的角度看青少年成瘾行为的移动健康数字应用干预:范围审查
Q4 Medicine Pub Date : 2023-03-15 DOI: 10.35755/jmedassocthai.2023.03.13800
Objective: To explore the scope of the published research studies on mHealth digital application interventions for youths with addictive behaviors, considering both the development and evaluation aspects. The main goal was to identify the concepts and theories underlying such applied technologies, detect any gaps, and provide recommendations. A secondary goal was to identify the components of mHealth digital application interventions that led to cognitive, emotional, and behavioral change among youths with addictive behaviors by drawing on Beck’s cognitive model and cognitive behavioral therapy (CBT).Materials and Methods: A scoping review was done based on York’s five-stage framework outlined by Arksey and O’Malley. Four leading databases were searched, PubMed, Science Direct, Web of Science, and Google Scholar.Results: There were 16 mHealth digital application interventions being developed to help youth overcome addiction issues. Most of the existing techniques involve dealing with youth’s stimuli, emotions, addictive behaviors, and physiology or physical reactions. These were the components of cross-sectional Beck’s cognitive model and CBT. In addition, most of the cognitive skill components were focused on managing reflective thoughts such as planning to stop addictive behaviors, intention to stop, encouraging more of creating positive thinking, or benefits of stop doing addictive behavior. No application component focused on identifying any implicit thought influenced of specific memories on addiction outcome expectancies such as the substance or self-intermediate belief, substance or self-core belief contained in Beck’s longitudinal cognitive model.Conclusion: Findings from the present scoping review suggest new routes for working with implicit thoughts. Some opportunities exist here for the development of CBT mHealth applications to raise awareness in youth concerning the implicit substance or self-concept appearing in Beck’s longitudinal cognitive model.Keywords: mHealth applications; CBT; Cognitive model; Beckian; Youth; Addictive behaviour; Substance
目的:从发展和评估两个方面探讨已发表的关于青少年成瘾行为的移动健康数字应用干预的研究范围。主要目标是确定这些应用技术背后的概念和理论,发现任何差距,并提供建议。第二个目标是通过借鉴贝克的认知模型和认知行为疗法(CBT),确定导致成瘾行为青少年认知、情感和行为改变的移动健康数字应用干预的组成部分。材料和方法:根据Arksey和O 'Malley概述的York的五阶段框架进行范围审查。搜索了四个主要的数据库,PubMed, Science Direct, Web of Science和Google Scholar。结果:正在开发16种移动健康数字应用干预措施,以帮助青少年克服成瘾问题。大多数现有的技术涉及处理青少年的刺激、情绪、成瘾行为和生理或身体反应。这些是贝克的横截面认知模型和CBT的组成部分。此外,大多数认知技能的组成部分都集中在管理反思思想上,比如计划停止成瘾行为、停止成瘾行为的意图、鼓励更多地创造积极思维,或者停止成瘾行为的好处。没有应用组件侧重于识别特定记忆对成瘾结果预期的内隐思维影响,如Beck纵向认知模型中包含的物质或自我中间信念,物质或自我核心信念。结论:本研究为内隐思维的研究提供了新的思路。CBT移动健康应用程序的发展存在一些机会,以提高青少年对Beck纵向认知模型中出现的内隐物质或自我概念的认识。关键词:移动健康应用;认知行为治疗;认知模型;Beckian;青春;上瘾行为;物质
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引用次数: 0
Successful Treatment of Nasal and Parotid Mycobacterium avium Complex Infection in Adult-Onset Immunodeficiency: A Case Report with Literature Review 成人发病的免疫缺陷患者鼻及腮腺鸟分枝杆菌复合感染的成功治疗:1例报告并文献复习
Q4 Medicine Pub Date : 2023-03-15 DOI: 10.35755/jmedassocthai.2023.03.13814
Non-tuberculous mycobacteria (NTM) infection has increasingly been reported throughout the world, especially in Asia. Autoantibodies to interferon-γ are implicated in the pathogenesis of adult-onset immunodeficiency resulting in multiple opportunistic infections, in particular NTM infection. There are few reports regarding Mycobacterium avium complex infection of the nasal cavity or parotid gland in this condition. The authors reported the first case of nasal and parotid Mycobacterium avium complex presenting with recurrent epistaxis, nasal mass, and parotitis successfully treated with combined systemic and topical anti-mycobacterial agents in Thailand.Keywords: Nasal and parotid Mycobacterium avium complex; Nontuberculous mycobacteria; Autoantibody to interferon-γ; Nasal mass; Epistaxis; Parotitis
非结核分枝杆菌(NTM)感染在世界各地越来越多地报道,特别是在亚洲。针对干扰素γ的自身抗体与成人发病性免疫缺陷的发病机制有关,导致多种机会性感染,特别是NTM感染。在这种情况下,关于鸟分枝杆菌复合感染鼻腔或腮腺的报道很少。作者报告了泰国第一例鼻和腮腺鸟分枝杆菌复合体,表现为复发性鼻出血、鼻肿块和腮腺炎,成功地用全身和局部抗分枝杆菌药物联合治疗。关键词:鼻腮腺鸟分枝杆菌复合体;Nontuberculous分枝杆菌;干扰素γ自身抗体;鼻质量;鼻出血;腮腺炎
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引用次数: 0
Predictive Value of Neutrophil-to-Lymphocyte Ratio at Admission for Chest X-Ray Progression in Hospitalized COVID-19 Patients 入院时中性粒细胞与淋巴细胞比值对COVID-19住院患者胸部x线进展的预测价值
Q4 Medicine Pub Date : 2023-03-15 DOI: 10.35755/jmedassocthai.2023.03.13815
C. Chantharakhit, A. Inkanuwat, K. Nouchpramool
Objective: Previous studies focused on using the neutrophil-to-lymphocyte ratio (NLR) to monitor COVID-19 patients as an early warning signal of severe COVID-19 infection. Results showed that NLR could also be used as a prognostic factor. In the present study, the role of NLR in predicting chest X-ray (CXR) progression in hospitalized COVID-19 patients was investigated.Materials and Methods: The present study was an ambispective observational cohort study that included COVID-19 patients admitted to the isolation ward and COVID-19 intensive care unit between July and September 2021 in Buddhasothorn Hospital, Chachoengsao, Thailand. NLR and demographic findings were analyzed.Results: Medical details of 564 patients were retrospectively analyzed using 3.24 as the cut-off value of the maximum Youden index to classify a high NLR group and a low NLR group. The estimated cumulative hazard function for CXR progression in the high NLR group was statistically significant, (HR 1.31, 95% CI 1.02 to 1.68, p=0.031). Univariate analysis suggested that high NLR value and three or more clinical risk factors (age 60 years or older, diabetes mellitus, chronic obstructive pulmonary disease, chronic kidney disease, cirrhosis, stroke, obesity, and immunocompromised) were associated with CXR progression, while multivariate analysis determined high NLR as an independent predictive marker for COVID-19 CXR progression (aOR 1.54, 95% CI 1.06 to 2.23, p=0.022). Using NLR along with pre-existing comorbidity risk factors significantly increased the predictive value for COVID-19 CXR progression (area under the ROC curve 0.565, p=0.017).Conclusion: High NLR at the time of hospitalization was identified as a simple predictor for COVID-19 CXR progression requiring close monitoring.Keywords: Neutrophil-to-lymphocyte ratio (NLR); COVID-19; Disease progression; Predictive factor; Hospitalization
目的:以往的研究主要是利用中性粒细胞与淋巴细胞比值(NLR)监测COVID-19患者,作为COVID-19严重感染的预警信号。结果显示NLR也可作为预后因素。本研究旨在探讨NLR在预测COVID-19住院患者胸部x线(CXR)进展中的作用。材料与方法:本研究是一项双视角观察队列研究,纳入了2021年7月至9月在泰国chachengsao市asothorn医院隔离病房和COVID-19重症监护病房住院的COVID-19患者。对NLR和人口统计学结果进行分析。结果:回顾性分析564例患者的医疗资料,以3.24作为最大约登指数的临界值划分高NLR组和低NLR组。高NLR组CXR进展的累积风险函数估计具有统计学意义(HR 1.31, 95% CI 1.02 ~ 1.68, p=0.031)。单因素分析表明,高NLR值和三个或三个以上临床危险因素(60岁及以上、糖尿病、慢性阻塞性肺病、慢性肾病、肝硬化、卒中、肥胖和免疫功能障碍)与CXR进展相关,而多因素分析确定高NLR是COVID-19 CXR进展的独立预测指标(aOR 1.54, 95% CI 1.06 ~ 2.23, p=0.022)。NLR与既往共病危险因素联合使用可显著提高COVID-19 CXR进展的预测值(ROC曲线下面积0.565,p=0.017)。结论:住院时的高NLR被确定为需要密切监测的COVID-19 CXR进展的简单预测因子。关键词:中性粒细胞与淋巴细胞比值;COVID-19;疾病进展;预测因子;住院治疗
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引用次数: 0
The Cochlear Implant Outcome and Factors Associated of Pre-Operative among Prelingual Deafness Patients Under 3 Years and 6 Months Old in Rajavithi Hospital: A Single Center Experience Rajavithi医院3岁6个月以下语前耳聋患者人工耳蜗植入效果及术前相关因素:单中心经验
Q4 Medicine Pub Date : 2023-03-15 DOI: 10.35755/jmedassocthai.2023.03.13797
Background: The recent government announcement that fees for cochlear implants in prelingual patients will be reimbursed means that this treatment will be more accessible in the near future. The data in the present study would form the baseline for improving the care process in Rajavithi Hospital.Objective: To study the outcomes of cochlear implants in prelingual hearing loss patients younger than three years and six months, and to determine preoperative assessment factors that affect the outcomes.Materials and Methods: A retrospective review was conducted of the medical records of prelingual deafness patients younger than three years and six months that underwent cochlear implants between 2013 and 2019. Forty patients were enrolled, and their demographic data, preoperative assessment, and Category Auditory Performance (CAP) score outcomes were recorded. The preoperative factors affecting the CAP score at 2 years post-operation were analyzed.Results: A CAP score above 5 at two years after cochlear implant, considered to be good habilitation, was reported in 55% (22 cases). After further follow up, the number of patients whose CAP score reached 5 or more was 31 (77.5%). The mean age of diagnosis was 13.28±9.38 months, and the mean age at surgery was 25.73±9.74 months. The preoperative factors associated with poor CAP scores were Goldenhar syndrome, Waardenburg syndrome, Autism, small inner ear canal, and poor eye contact. The differences in preoperative factors between patients with CAP scores of 5 or more and those with scores less than 5 at two years after cochlear implant were not statistically significant.Conclusion: The outcomes of cochlear implant operations may be improved by early age at surgery, which will be assessed by the Newborn Hearing Screening policy. Preoperative assessment factors associated with poor outcomes were identified, but they were not statistically significant in the present study.Keywords: Cochlear implant; CAP score; Preoperative factors
背景:最近政府宣布,对语前患者进行人工耳蜗植入的费用将得到报销,这意味着在不久的将来这种治疗将更容易获得。本研究的数据将构成改善拉贾维提医院护理过程的基线。目的:研究3岁零6个月以下语前听力损失患者人工耳蜗植入的预后,并确定影响预后的术前评估因素。材料与方法:回顾性分析2013年至2019年接受人工耳蜗植入的3岁零6个月以下语前耳聋患者的病历。40例患者入组,记录他们的人口统计数据、术前评估和类别听觉表现评分结果。分析术前影响术后2年CAP评分的因素。结果:22例(55%)人工耳蜗术后2年CAP评分在5分以上,认为康复良好。进一步随访后,CAP评分达到5分及以上的患者31例(77.5%)。平均诊断年龄13.28±9.38个月,平均手术年龄25.73±9.74个月。术前与CAP评分差相关的因素有Goldenhar综合征、Waardenburg综合征、自闭症、内耳道小、眼神交流差。人工耳蜗术后2年,CAP评分在5分及以上的患者与低于5分的患者术前因素差异无统计学意义。结论:早期人工耳蜗手术可改善手术效果,新生儿听力筛查政策可对其进行评估。术前评估因素与不良预后相关,但在本研究中无统计学意义。关键词:人工耳蜗;帽分数;术前因素
{"title":"The Cochlear Implant Outcome and Factors Associated of Pre-Operative among Prelingual Deafness Patients Under 3 Years and 6 Months Old in Rajavithi Hospital: A Single Center Experience","authors":"","doi":"10.35755/jmedassocthai.2023.03.13797","DOIUrl":"https://doi.org/10.35755/jmedassocthai.2023.03.13797","url":null,"abstract":"Background: The recent government announcement that fees for cochlear implants in prelingual patients will be reimbursed means that this treatment will be more accessible in the near future. The data in the present study would form the baseline for improving the care process in Rajavithi Hospital.\u0000\u0000Objective: To study the outcomes of cochlear implants in prelingual hearing loss patients younger than three years and six months, and to determine preoperative assessment factors that affect the outcomes.\u0000\u0000Materials and Methods: A retrospective review was conducted of the medical records of prelingual deafness patients younger than three years and six months that underwent cochlear implants between 2013 and 2019. Forty patients were enrolled, and their demographic data, preoperative assessment, and Category Auditory Performance (CAP) score outcomes were recorded. The preoperative factors affecting the CAP score at 2 years post-operation were analyzed.\u0000\u0000Results: A CAP score above 5 at two years after cochlear implant, considered to be good habilitation, was reported in 55% (22 cases). After further follow up, the number of patients whose CAP score reached 5 or more was 31 (77.5%). The mean age of diagnosis was 13.28±9.38 months, and the mean age at surgery was 25.73±9.74 months. The preoperative factors associated with poor CAP scores were Goldenhar syndrome, Waardenburg syndrome, Autism, small inner ear canal, and poor eye contact. The differences in preoperative factors between patients with CAP scores of 5 or more and those with scores less than 5 at two years after cochlear implant were not statistically significant.\u0000\u0000Conclusion: The outcomes of cochlear implant operations may be improved by early age at surgery, which will be assessed by the Newborn Hearing Screening policy. Preoperative assessment factors associated with poor outcomes were identified, but they were not statistically significant in the present study.\u0000\u0000Keywords: Cochlear implant; CAP score; Preoperative factors","PeriodicalId":17486,"journal":{"name":"Journal of the Medical Association of Thailand = Chotmaihet thangphaet","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90224927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association Between Sleep Quality and Quality of Life Among Medical Students in Chiang Mai University 清迈大学医学生睡眠质量与生活质量的关系
Q4 Medicine Pub Date : 2023-03-15 DOI: 10.35755/jmedassocthai.2023.03.13808
Objective: To explore and compare the sleep quality between pre-clinical and clinical medical students. The present study also assessed the influence of sleep quality on the quality of life in four domains, physical, psychological, social relationships, and environment.Materials and Methods: A cross-sectional study was conducted among 261 second-year students and 241 fourth-year students from the Faculty of Medicine, Chiang Mai University as the representatives of preclinical and clinical medical students. Participants completed questionnaires consisting of the Pittsburgh Sleep Quality Index (PSQI) Thai version and WHOQOL-BREF-THAI to assess sleep quality and quality of life. The sleep quality was examined by chi-square test for the comparison between the two groups. Linear regression was used to evaluate the overall influence of sleep quality on each domain of the quality of life after adjusting for other covariates.Results: Two hundred sixty-one participants or 46.7% had poor sleep quality with a PSQI of 6.5 or more. The sleep quality compared between the academic years had significantly worse results (p<0.001) in the preclinical students. Sleep latency and sleep disturbance were the two components of sleep quality that were statistically poorer in the preclinical students (p<0.001). Poor sleep was significantly associated with a poor quality of life in all domains (p<0.001). Each score increased in the global PSQI score, 2.924 score of total WHOQOL-BREF-THAI would be diminished, resulting in an impaired quality of life (p<0.001).Conclusion: The prevalence of poor sleep quality was significantly higher in the preclinical year. As poorer sleep is statistically associated with the poorer quality of life, the curriculum and schedule should give consideration and provision for good sleep quality, especially in preclinical students for the improvement of medical student’s well-being.Keywords: Sleep quality; Quality of life; Medical students
目的:探讨临床前医学生与临床医学生的睡眠质量。本研究还从生理、心理、社会关系和环境四个方面评估了睡眠质量对生活质量的影响。材料与方法:对清迈大学医学院261名二年级学生和241名四年级学生进行横断面研究,分别作为临床前和临床医学学生的代表。参与者完成由匹兹堡睡眠质量指数(PSQI)泰国版和WHOQOL-BREF-THAI组成的问卷来评估睡眠质量和生活质量。两组患者的睡眠质量比较采用卡方检验。在调整其他协变量后,使用线性回归来评估睡眠质量对生活质量各个领域的总体影响。结果:261名参与者(46.7%)睡眠质量较差,PSQI为6.5或更高。临床前学生的睡眠质量在学年之间的比较结果明显较差(p<0.001)。睡眠潜伏期和睡眠障碍是临床前学生睡眠质量的两个组成部分,统计学上较差(p<0.001)。在所有领域中,睡眠质量差与生活质量差显著相关(p<0.001)。PSQI总分每增加1分,WHOQOL-BREF-THAI总分2.924分就会降低,导致生活质量下降(p<0.001)。结论:临床前一年睡眠质量差的患病率明显高于临床前一年。由于较差的睡眠与较差的生活质量在统计上是相关的,因此课程和时间表应该考虑和提供良好的睡眠质量,特别是在临床前学生中,以提高医学生的幸福感。关键词:睡眠质量;生活质量;医学专业的学生
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引用次数: 0
Relationship between Health Literacy in Disease Prevention and Quality of Life of Older People in the Region Public Health of Thailand 泰国公共卫生区域老年人疾病预防健康素养与生活质量的关系
Q4 Medicine Pub Date : 2023-03-15 DOI: 10.35755/jmedassocthai.2023.03.13816
Objective: To examine relationship between health literacy (HL) in disease prevention associated with the quality of life (QOL) of the older people.Materials and Methods: Three hundred sixty elderly persons aged 60 to 80 years living in the Health District 7 of Thailand were included in this study. The subjects were randomized by the multi-stage sampling technique. The data were collected using the HL in disease prevention and WHOQOL-OLD questionnaire. The data were analyzed by descriptive statistics and multiple logistic regression analysis.Results: The results showed that most of the HL in disease prevention was in the sufficient to excellent level at 71.67%, and most of the QOL was in the good level at 85.84%. The factors relating to the QOL in the elderly included HL in disease prevention at a sufficient to excellent level (adjusted OR 2.17, 95% CI 1.18 to 3.99, p=0.013).Conclusion: HL in disease prevention is associated with QOL in the older people. Therefore, HL in disease prevention among the older people should be continually strengthened to have a good QOL as long as possible in old age.Keywords: Health Literacy; Quality of Life; Older people; Associated factors
目的:探讨老年人疾病预防健康素养(HL)与生活质量(QOL)的关系。材料与方法:本研究选取了居住在泰国第7卫生区的360名年龄在60 ~ 80岁的老年人。研究对象采用多阶段抽样法随机化。采用疾病预防问卷和WHOQOL-OLD问卷收集数据。资料采用描述性统计和多元logistic回归分析。结果:结果显示,大部分HL在疾病预防方面处于充分至优水平(71.67%),大部分QOL处于良好水平(85.84%)。影响老年人生活质量的因素包括:HL在疾病预防方面处于充分至优秀水平(调整后OR为2.17,95% CI为1.18 ~ 3.99,p=0.013)。结论:HL预防与老年人生活质量相关。因此,应不断加强HL在老年人疾病预防中的作用,使老年人尽可能长时间地拥有良好的生活质量。关键词:健康素养;生活质量;老年人;相关的因素
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引用次数: 0
Efficacy of Preoperative Intravenous Tranexamic Acid Before Cesarean Section in Placenta Previa: A Randomized Double Blind Control Trial 前置胎盘剖宫产术前静脉注射氨甲环酸的疗效:一项随机双盲对照试验
Q4 Medicine Pub Date : 2023-03-15 DOI: 10.35755/jmedassocthai.2023.03.13798
Background: Placenta previa is a common cause of postpartum hemorrhage (PPH) that contributes substantively to maternal morbidity and mortality rates. Tranexamic acid is an antifibrinolytic drug that is useful for the treatment of PPH. The recommendation from many guidelines is to start giving tranexamic acid as soon as PPH is diagnosed to reduce postpartum blood loss. Furthermore, some studies report the beneficial use of tranexamic acid given as a prophylactic before Cesarean section to decrease intraoperative blood loss and prevent PPH. To the authors’ knowledge, in high-risk obstetrics case such as placenta previa, there was insufficient data to support recommendations of the use of tranexamic acid for prevent PPH.Objective: To evaluate the efficacy of supplementary intravenous tranexamic acid before cesarean section versus prophylactic intravenous oxytocin after placenta delivery alone to decrease intraoperative blood loss and prevent PPH in placenta previa.Material and Methods: The present study conducted a double blinded placebo control trial comparing adjunct 1 g tranexamic acid given intravenously before skin incision with prophylactic intravenous oxytocin after placenta delivery alone before cesarean section for placenta previa. The study recruited 60 women who were diagnosed with placenta previa at gestational age (GA) of more than 28 completed weeks undergoing emergency cesarean section due to active bleeding or scheduled for elective cesarean section at 37 completed weeks at Chonburi Hospital between July 2021 and July 2022. The primary outcome was intraoperative blood loss.Results: Sixty diagnosed placenta previa women were recruited, with 30 patients per group. Group I patients were given 1 g tranexamic acid and Group II were given a placebo of 100 ml NSS before skin incision. Both groups received intravenous oxytocin 20 units after placenta delivery. The main outcome showed that preoperative tranexamic acid intravenous reduced intraoperative blood loss significantly compared with the placebo at 349.5 ml (range of 168 to 2,200) versus 619 ml (range of 288 to 3,243), p<0.001. The secondary outcome showed a significant decrease in the incidence of PPH at 4 (13.33%) versus 10 (33.33%), p=0.030 and decreased in the incidence of blood transfusion of more than one unit from 5 (16.67%) versus 13 (43.33%), p=0.047.Conclusion: Prophylactic supplementary 1 g tranexamic acid intravenously before cesarean section to prophylactic intravenous oxytocin after placental delivery was found to effectively reduce intraoperative blood loss and PPH.Keywords: Tranexamic acid; Preoperative; Placenta previa; Intraoperative blood loss; Cesarean section
背景:前置胎盘是产后出血(PPH)的常见原因,是导致产妇发病率和死亡率的重要原因。氨甲环酸是一种抗纤溶药物,可用于治疗PPH。许多指南的建议是,一旦诊断出PPH,就开始给予氨甲环酸,以减少产后失血。此外,一些研究报道了剖宫产术前给予氨甲环酸作为预防措施,以减少术中出血量和预防PPH的有益使用。据作者所知,在高危产科病例中,如前置胎盘,没有足够的数据支持使用氨甲环酸预防PPH的建议。目的:评价剖宫产术前补充静脉氨甲环酸与胎盘娩出后预防性静脉催产素在减少术中出血量和预防前置胎盘PPH方面的疗效。材料与方法:本研究采用双盲安慰剂对照试验,比较剖宫产前切开皮肤前静脉注射1 g氨甲环酸与胎盘娩出后单独预防性静脉注射催产素。该研究招募了60名在2021年7月至2022年7月期间在春武里医院(Chonburi Hospital)被诊断患有前置胎盘(GA)超过28周的妇女,她们因活动性出血接受了紧急剖宫产手术,或计划在37周完成剖宫产手术。主要结局为术中出血量。结果:60名确诊为前置胎盘的女性被招募,每组30名患者。ⅰ组患者在切开皮肤前给予氨甲环酸1 g,ⅱ组患者给予NSS 100 ml安慰剂。两组均在胎盘分娩后静脉注射催产素20单位。主要结果显示,术前静脉注射氨甲环酸与安慰剂相比,术中出血量显著减少,分别为349.5 ml(范围为168 ~ 2200)和619 ml(范围为288 ~ 3243),p<0.001。次要结局显示PPH发生率从4(13.33%)比10(33.33%)显著降低,p=0.030;输血1个单位以上的发生率从5(16.67%)比13(43.33%)显著降低,p=0.047。结论:剖宫产术前预防性补充氨甲环酸1 g,胎盘分娩后预防性静脉注射催产素,可有效减少术中出血量和PPH。关键词:氨甲环酸;术前;前置胎盘;术中出血量;剖腹产
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引用次数: 0
Comparing the Efficacy and Success Rate of Radial Artery Approach under Ultrasound Guidance and Palpation Technique for Coronary Intervention at Central Chest Institute of Thailand 泰国中央胸科研究所超声引导下桡动脉入路与触诊技术在冠状动脉介入治疗中的疗效及成功率比较
Q4 Medicine Pub Date : 2023-03-15 DOI: 10.35755/jmedassocthai.2023.03.13807
Background: Previous studies of ultrasound guidance for transradial artery access during coronary angiography or interventional procedures demonstrate improving success rate, number of attempts, and short-time access in radial artery cannulation.Objective: To compare the benefit of ultrasound guidance radial artery access during coronary angiography (CAG) or percutaneous coronary intervention (PCI) with palpation technique in experienced and inexperienced operators.Materials and Methods: A randomized prospective study was performed between October 2021 and April 2022. One hundred sixty-four patients were randomized into three groups. The first group, group I (55 cases), underwent radial artery puncture with ultrasound guidance by an experienced interventionist. The second group, group II (56 cases), underwent radial artery puncture using the palpation technique by another experienced interventionist. The third group, group III (53 cases), was also assigned to radial artery puncture with the palpation technique, however, performed by three interventional cardiology fellows.Results: The success rate of radial cannulation was 55 (100%) in group I, 52 (92.9%) in group II, and 48 (90.6%) in group III (p=0.060). Firstattempt success rates in the three groups were 83.6%, 75%, and 69.8%, respectively (p=0.233). The median number of attempts was not significantly different (p=0.208). Time to access the radial artery in group I was reduced significantly compared to the palpation technique in group II and group III (p<0.001). There were no significant differences in complications such as difficult access, access site crossover, radial spasm, and hematoma/ bleeding complication (p=0.135, 0.367, 0.132, and 0.700, respectively).Conclusion: In experienced operators, an ultrasound-guided technique has been shown to have beneficial advantages in reducing the time to access radial artery cannulation compared to experienced and inexperienced operators using the palpation technique.Keywords: Transradial catheterization; Ultrasound guide
背景:在冠状动脉造影或介入手术中,超声引导经桡动脉插管的研究表明,桡动脉插管的成功率、次数和时间都有所提高。目的:比较超声引导桡动脉进入冠状动脉造影(CAG)或经皮冠状动脉介入治疗(PCI)与触诊技术在经验丰富和经验不足的操作人员中的优势。材料和方法:一项随机前瞻性研究于2021年10月至2022年4月进行。164名患者被随机分为三组。第一组55例,由经验丰富的介入医师在超声引导下行桡动脉穿刺。第二组(56例)由另一位经验丰富的介入医师采用触诊技术穿刺桡动脉。第三组,III组(53例),也被分配到用触诊技术进行桡动脉穿刺,然而,由三位介入心脏病学研究员执行。结果:ⅰ组桡动脉插管成功率为55例(100%),ⅱ组为52例(92.9%),ⅲ组为48例(90.6%)(p=0.060)。三组患者首次尝试成功率分别为83.6%、75%、69.8% (p=0.233)。尝试次数中位数差异无统计学意义(p=0.208)。与II组和III组的触诊技术相比,I组到达桡动脉的时间明显缩短(p<0.001)。两组患者通路困难、通路交叉、桡骨痉挛、血肿出血等并发症发生率差异无统计学意义(p值分别为0.135、0.367、0.132、0.700)。结论:在经验丰富的操作人员中,与经验丰富和经验不足的操作人员使用触诊技术相比,超声引导技术在减少桡动脉插管时间方面具有有益的优势。关键词:经桡动脉置管;超声引导
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引用次数: 0
Towards Integrating Health Economics into Medical Education in Thailand 在泰国将卫生经济学纳入医学教育
Q4 Medicine Pub Date : 2023-03-15 DOI: 10.35755/jmedassocthai.2023.03.13812
Objective: To describe the attempts to integrate health economics (HE) into medical education in Thailand.Materials and Methods: A national survey was launched to all medical education centers in Thailand to discern the situation and gaps in HE teaching. Discussions about improving HE education were held among experienced educators. As a result, the HE working group, comprising experienced medical teachers in HE, was initiated with the aim of recommending the essential contents for HE education. The HE working group also helped preparing a HE curriculum and instructional media assisted general medical educators in HE teaching. Distribution of learning materials developed was planned.Results: Results from the survey revealed gaps in HE teaching, including the lack of HE teaching in clinical curricula, inconsistency in teaching standards, and scarcity of teaching materials and resource persons. The HE working group developed a spiral-based HE curriculum for medical training from undergraduate to graduate levels. Moreover, HE study guides were proposed as teaching aids. Additionally, an example to integrate HE into other medical discipline was demonstrated in the undergraduate curriculum of Family Medicine. Workshops “training for the trainers” were successfully arranged twice. All produced materials, including HE essential contents, curriculum, and study guides, as well as teaching experience were shared to the medical teachers in this regard.Conclusion: While a number of efforts had been established to integrate HE into medical education, further attempts are still required to continuously improve HE teaching.Keywords: Health economics; Study guide; Curriculum; Situation
目的:介绍泰国将卫生经济学(HE)纳入医学教育的尝试。材料与方法:对泰国所有医学教育中心开展了一项全国性调查,以了解高等教育教学的情况和差距。有经验的教育工作者就如何改进高等教育进行了讨论。因此,成立了由高等教育经验丰富的医学教师组成的高等教育工作组,目的是建议高等教育的基本内容。高等教育工作组还帮助编制高等教育课程,教学媒体协助普通医学教育者进行高等教育教学。已计划分发所编制的学习材料。结果:调查结果揭示了高等教育教学存在的不足,包括临床课程高等教育教学缺失、教学标准不统一、教材和人才资源匮乏等。高等教育工作组为从本科到研究生的医学培训制定了螺旋式高等教育课程。此外,还提出了高等教育学习指南作为教学辅助工具。并以家庭医学本科课程为例,展示了高等教育与其他医学学科的结合。成功举办了两次“培训师培训”工作坊。所有制作的教材,包括基本内容、课程和学习指南,以及教学经验,都与医学教师分享。结论:高等医学教育在整合高等医学教育方面做了一些努力,但高等医学教育教学仍需不断改进。关键词:卫生经济学;学习指南;课程;情况
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引用次数: 0
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Journal of the Medical Association of Thailand = Chotmaihet thangphaet
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