A. Mohan, M. Arjun, D. Rajasekhar, A. Chandra, BVijayalakshmi Devi, S. Sangaraju
Context: Rheumatic heart disease (RHD). Aim: The aim of the study was to study the clinical presentation and pattern of cardiac involvement in adult patients with RHD. Settings and Design: This was a prospective observational study from a tertiary care hospital in South India. Subjects and Methods: Consecutive adult patients diagnosed with and treated for RHD in our tertiary care teaching hospital in Tirupati were screened for inclusion. In all patients, details of appropriate laboratory and imaging investigations that have been carried out were noted. Statistical Analysis Used: Descriptive statistics (frequencies, mean standard deviation, and median [interquartile range (IQR)]) were reported. Results: A total of 120 patients were enrolled. Their mean age was 45.7–12.2 years; there were 79 females. The median (IQR) follow-up was 364 (156–702) weeks. Single-valve disease was seen in 51.7% (n = 62); others (n = 58) had multivalvular disease (mitral stenosis [MS] + aortic regurgitation [AR] [n = 47, 81%] and mitral regurgitation + AR [n = 11, 19%]). Among patients with single-valve involvement, 58 (93.5%) had mitral valve disease. Overall, 116 of 120 (96.6%) patients had mitral valve involvement. Among patients with mitral valve disease (n = 116), MS was severe in 62 (51.6%). Atrial fibrillation was evident in 59 (49.2%) patients; of these, 8 had cardioembolic strokes. Forty-four (36.7%) had undergone percutaneous transvenous mitral commissurotomy. Prosthetic mitral valve obstruction was observed in 2/20 patients who had undergone mitral valve replacement or double-valve replacement. Conclusions: In patients with RHD, mitral valve involvement (either alone or in combination with the aortic valve) was most common; MS was most common.
{"title":"Clinical presentation and pattern of cardiac involvement in patients with rheumatic heart disease: A prospective observational study","authors":"A. Mohan, M. Arjun, D. Rajasekhar, A. Chandra, BVijayalakshmi Devi, S. Sangaraju","doi":"10.4103/jpcs.jpcs_7_23","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_7_23","url":null,"abstract":"Context: Rheumatic heart disease (RHD). Aim: The aim of the study was to study the clinical presentation and pattern of cardiac involvement in adult patients with RHD. Settings and Design: This was a prospective observational study from a tertiary care hospital in South India. Subjects and Methods: Consecutive adult patients diagnosed with and treated for RHD in our tertiary care teaching hospital in Tirupati were screened for inclusion. In all patients, details of appropriate laboratory and imaging investigations that have been carried out were noted. Statistical Analysis Used: Descriptive statistics (frequencies, mean standard deviation, and median [interquartile range (IQR)]) were reported. Results: A total of 120 patients were enrolled. Their mean age was 45.7–12.2 years; there were 79 females. The median (IQR) follow-up was 364 (156–702) weeks. Single-valve disease was seen in 51.7% (n = 62); others (n = 58) had multivalvular disease (mitral stenosis [MS] + aortic regurgitation [AR] [n = 47, 81%] and mitral regurgitation + AR [n = 11, 19%]). Among patients with single-valve involvement, 58 (93.5%) had mitral valve disease. Overall, 116 of 120 (96.6%) patients had mitral valve involvement. Among patients with mitral valve disease (n = 116), MS was severe in 62 (51.6%). Atrial fibrillation was evident in 59 (49.2%) patients; of these, 8 had cardioembolic strokes. Forty-four (36.7%) had undergone percutaneous transvenous mitral commissurotomy. Prosthetic mitral valve obstruction was observed in 2/20 patients who had undergone mitral valve replacement or double-valve replacement. Conclusions: In patients with RHD, mitral valve involvement (either alone or in combination with the aortic valve) was most common; MS was most common.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"9 1","pages":"116 - 120"},"PeriodicalIF":0.1,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48346439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The current case describes the successful implantation of a leadless pacemaker in an elderly patient with multiple complexities. The patient had an in situ cardiac pacemaker with a suspected displaced right ventricular lead and was stabilized using temporary pacemaker implantation. The angiogram revealed obstructed subclavian veins; hence, a leadless pacemaker was successfully implanted.
{"title":"Leadless pacemaker – A savior in crisis","authors":"Ashwin Tumkur, Golla Sudhakar","doi":"10.4103/jpcs.jpcs_31_23","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_31_23","url":null,"abstract":"The current case describes the successful implantation of a leadless pacemaker in an elderly patient with multiple complexities. The patient had an in situ cardiac pacemaker with a suspected displaced right ventricular lead and was stabilized using temporary pacemaker implantation. The angiogram revealed obstructed subclavian veins; hence, a leadless pacemaker was successfully implanted.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"9 1","pages":"152 - 154"},"PeriodicalIF":0.1,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48917979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maharshi Patel, T. Rao, S. Acharya, S. Shukla, S. Sushanth Kumar
{"title":"Isolated double orifice mitral valve: An extremely rare cardiac anomaly","authors":"Maharshi Patel, T. Rao, S. Acharya, S. Shukla, S. Sushanth Kumar","doi":"10.4103/jpcs.jpcs_85_22","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_85_22","url":null,"abstract":"","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"9 1","pages":"158 - 159"},"PeriodicalIF":0.1,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47226923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prognostic markers in heart failure: Further insights","authors":"R. Magoon, Devishree Das","doi":"10.4103/jpcs.jpcs_43_23","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_43_23","url":null,"abstract":"","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"9 1","pages":"160 - 160"},"PeriodicalIF":0.1,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46612809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bharath Konda, Krishna Reddy Parvathareddy, Praveen Nagula, Z. Hussain
Cardiac catheterization is performed for both therapeutic and diagnostic reasons. Like any invasive procedure, cardiac catheterization is associated with complications; hence, the decision to undertake the procedure should be based on the risks and benefits. In terms of vascular problems, the radial artery approach to cardiac catheterization is preferable to femoral artery access. Rare cases of radial artery pseudoaneurysms (PSAs) have been documented. The incidence of radial PSAs, a recognized complication of radial access, has been gradually rising due to the increasing number of radial procedures in cardiology. We report a case of a 67-year-old female who had a large radial PSA following transradial (TR) coronary angioplasty with stenting. She was managed conservatively with TR band application, intermittent manual compression, and dressing.
{"title":"Radial artery pseudoaneurysm following transradial percutaneous coronary intervention","authors":"Bharath Konda, Krishna Reddy Parvathareddy, Praveen Nagula, Z. Hussain","doi":"10.4103/jpcs.jpcs_49_23","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_49_23","url":null,"abstract":"Cardiac catheterization is performed for both therapeutic and diagnostic reasons. Like any invasive procedure, cardiac catheterization is associated with complications; hence, the decision to undertake the procedure should be based on the risks and benefits. In terms of vascular problems, the radial artery approach to cardiac catheterization is preferable to femoral artery access. Rare cases of radial artery pseudoaneurysms (PSAs) have been documented. The incidence of radial PSAs, a recognized complication of radial access, has been gradually rising due to the increasing number of radial procedures in cardiology. We report a case of a 67-year-old female who had a large radial PSA following transradial (TR) coronary angioplasty with stenting. She was managed conservatively with TR band application, intermittent manual compression, and dressing.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"9 1","pages":"145 - 147"},"PeriodicalIF":0.1,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43253230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Preradović, S. Miljković, Ljiljana Kos, A. Šukalo, U. Glamočlija, A. Avdić, Meliha Mehić
Context: Rivaroxaban is an oral direct factor Xa inhibitor reducing the risk of systemic embolism and stroke in patients with nonvalvular atrial fibrillation. Aims: The primary objective was to evaluate the effectiveness of rivaroxaban therapy in reducing the risk of systemic embolism and stroke in patients with nonvalvular atrial fibrillation, whereas secondary objectives were to monitor therapy safety and the patients' adherence to treatment. Settings and Design: The prospective, postmarketing clinical trial was conducted on patients with nonvalvular atrial fibrillation with one or more risk factors, such as congestive heart failure, hypertension, and diabetes mellitus, who suffered a stroke or a transient ischemic attack. Subjects and Methods: At the baseline visit, the CHA2DS2 score was determined, and therapy was introduced. At three control visits (1, 3, and 6 months after baseline), systemic embolism, stroke, bruises, or bleeding occurrences were recorded. Furthemore, adverse events were monitored, and the Morisky score (MMAS-8) for treatment compliance was determined. Results were compared to previous studies. Results: The study included 471 patients. The incidence rate in events per 100 patient-years (95% confidence interval) was 2.6 (0.1–5.1) for systemic embolism and 4.3 (1.6–7.0) for stroke. The most common form of bleeding during rivaroxaban therapy was epistaxis. Adverse events were reported in 12 (2.7%) patients. Therapy adherence was in the range of medium adherence for the entire study period, with the average score decreasing significantly from the 1st to 6th months (P < 0.001). Conclusions: Rivaroxaban showed good efficacy and safety in reducing the risk of systemic embolism and stroke in patients with nonvalvular atrial fibrillation including patients with comorbidities.
{"title":"Efficacy and safety of rivaroxaban in prevention and therapy of thromboembolic events in patients with nonvalvular atrial fibrillation","authors":"T. Preradović, S. Miljković, Ljiljana Kos, A. Šukalo, U. Glamočlija, A. Avdić, Meliha Mehić","doi":"10.4103/jpcs.jpcs_40_23","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_40_23","url":null,"abstract":"Context: Rivaroxaban is an oral direct factor Xa inhibitor reducing the risk of systemic embolism and stroke in patients with nonvalvular atrial fibrillation. Aims: The primary objective was to evaluate the effectiveness of rivaroxaban therapy in reducing the risk of systemic embolism and stroke in patients with nonvalvular atrial fibrillation, whereas secondary objectives were to monitor therapy safety and the patients' adherence to treatment. Settings and Design: The prospective, postmarketing clinical trial was conducted on patients with nonvalvular atrial fibrillation with one or more risk factors, such as congestive heart failure, hypertension, and diabetes mellitus, who suffered a stroke or a transient ischemic attack. Subjects and Methods: At the baseline visit, the CHA2DS2 score was determined, and therapy was introduced. At three control visits (1, 3, and 6 months after baseline), systemic embolism, stroke, bruises, or bleeding occurrences were recorded. Furthemore, adverse events were monitored, and the Morisky score (MMAS-8) for treatment compliance was determined. Results were compared to previous studies. Results: The study included 471 patients. The incidence rate in events per 100 patient-years (95% confidence interval) was 2.6 (0.1–5.1) for systemic embolism and 4.3 (1.6–7.0) for stroke. The most common form of bleeding during rivaroxaban therapy was epistaxis. Adverse events were reported in 12 (2.7%) patients. Therapy adherence was in the range of medium adherence for the entire study period, with the average score decreasing significantly from the 1st to 6th months (P < 0.001). Conclusions: Rivaroxaban showed good efficacy and safety in reducing the risk of systemic embolism and stroke in patients with nonvalvular atrial fibrillation including patients with comorbidities.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"9 1","pages":"110 - 115"},"PeriodicalIF":0.1,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49590686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarvesh Kumar, Vivek Tewarson, M. Hakim, Bhupendra Kumar, K. Rahul, Shobhit Kumar, Sushil Singh
The sinus of Valsalva aneurysm is a rare pathological lesion found in around 0.09% of the population. Surgical management is usually indicated for large aneurysms causing hemodynamic compromise or aneurysms that enlarge progressively. Surgical approaches for unruptured aneurysms include patch or primary closure. The article describes our technique for closing the small sinus of a Valsalva aneurysm discovered incidentally during surgery for aortic valve replacement. Interrupted pledgeted sutures placed for fixing the mechanical prosthetic aortic valve (St Judes Medical TM) were passed through the aortic valve annulus and the superior edge of the aneurysm sac, resulting in transverse primary closure of the aneurysm opening in the aortic root.
{"title":"A simple and innovative repair of an incidentally discovered sinus of valsalva aneurysm during aortic valve replacement","authors":"Sarvesh Kumar, Vivek Tewarson, M. Hakim, Bhupendra Kumar, K. Rahul, Shobhit Kumar, Sushil Singh","doi":"10.4103/jpcs.jpcs_46_23","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_46_23","url":null,"abstract":"The sinus of Valsalva aneurysm is a rare pathological lesion found in around 0.09% of the population. Surgical management is usually indicated for large aneurysms causing hemodynamic compromise or aneurysms that enlarge progressively. Surgical approaches for unruptured aneurysms include patch or primary closure. The article describes our technique for closing the small sinus of a Valsalva aneurysm discovered incidentally during surgery for aortic valve replacement. Interrupted pledgeted sutures placed for fixing the mechanical prosthetic aortic valve (St Judes Medical TM) were passed through the aortic valve annulus and the superior edge of the aneurysm sac, resulting in transverse primary closure of the aneurysm opening in the aortic root.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"9 1","pages":"155 - 157"},"PeriodicalIF":0.1,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45953826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aspirin is the most used antiplatelet agent for secondary prophylaxis of atherosclerotic cardiovascular diseases. Individual variability in aspirin responsiveness has been widely reported. The current recommendations do not take these variations into consideration. Current guidelines recommend 75–100 mg of once-daily aspirin in all patients for secondary prevention. However, “one-dose-fits-all” may not be the appropriate aspirin dosing strategy. Based on our review, we suggest that patients with inadequate aspirin responsiveness are at increased risk of recurrent cardiovascular events. Noncompliance is the most common cause of poor aspirin response. Ensuring adequate compliance and avoiding concomitant ingestion of nonaspirin nonsteroidal anti-inflammatory drugs and bedtime ingestion of aspirin can help achieve adequate aspirin-mediated antiplatelet activity. A low-dose, twice-daily regimen is the preferred strategy in “high-risk” groups.
{"title":"Aspirin strategy for secondary prevention of atherosclerotic cardiovascular diseases: A narrative review","authors":"Nischal Hegde, Navin Mathew","doi":"10.4103/jpcs.jpcs_46_22","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_46_22","url":null,"abstract":"Aspirin is the most used antiplatelet agent for secondary prophylaxis of atherosclerotic cardiovascular diseases. Individual variability in aspirin responsiveness has been widely reported. The current recommendations do not take these variations into consideration. Current guidelines recommend 75–100 mg of once-daily aspirin in all patients for secondary prevention. However, “one-dose-fits-all” may not be the appropriate aspirin dosing strategy. Based on our review, we suggest that patients with inadequate aspirin responsiveness are at increased risk of recurrent cardiovascular events. Noncompliance is the most common cause of poor aspirin response. Ensuring adequate compliance and avoiding concomitant ingestion of nonaspirin nonsteroidal anti-inflammatory drugs and bedtime ingestion of aspirin can help achieve adequate aspirin-mediated antiplatelet activity. A low-dose, twice-daily regimen is the preferred strategy in “high-risk” groups.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"9 1","pages":"99 - 103"},"PeriodicalIF":0.1,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42263364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Acute coronary syndrome (ACS) is witnessing a demographic transition with increasing prevalence among younger individuals (≤45 years). Hence, this study was designed to evaluate the clinical features, risk factors, and angiographic profile of young (aged ≤ 45 years) patients with ACS and to compare it with the older (aged >45 years) patients with ACS. Materials and Methods: An observational study was conducted at a tertiary care center in India from July 2020 to December 2021. A total of 157 patients were enrolled, among which 90 patients were included in cases (group-I). The inclusion criteria were patients presenting with ACS aged between 18 and 45 years. There were two control groups, including 34 patients with ACS (aged >45 years) in Group II and 33 healthy volunteers in Group III (aged 18–45 years). Baseline demographic details, risk factors, and angiographic profile of patients with ACS in each group were recorded and compared. Results: Mean age of Group I was 39.79 ± 5.15 years and of Group II was 59.74 ± 8.21 years. Smoking (P = 0.027) and family history of coronary artery disease (P = 0.022) were the significant risk factors of ACS in Group I. Compared to non-ST elevation myocardial infarction (16.7%), ST-elevation myocardial infarction (83.3%) was predominant among younger patients with ACS. Single-vessel disease was prevalent among younger patients (62.2%) as compared to older patients with ACS (41.20%). Conclusion: Younger patients with ACS exhibited a distinct clinical and angiographic profile compared to older patients with ACS.
{"title":"Acute coronary syndrome in young (≤45 years) patients: An observational study","authors":"Chandrashekhar Pandey, Reena Singh, Pankaj Vasantrao Talokar, Rujuta Parikh, Gaurav Singh","doi":"10.4103/jpcs.jpcs_3_23","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_3_23","url":null,"abstract":"Background: Acute coronary syndrome (ACS) is witnessing a demographic transition with increasing prevalence among younger individuals (≤45 years). Hence, this study was designed to evaluate the clinical features, risk factors, and angiographic profile of young (aged ≤ 45 years) patients with ACS and to compare it with the older (aged >45 years) patients with ACS. Materials and Methods: An observational study was conducted at a tertiary care center in India from July 2020 to December 2021. A total of 157 patients were enrolled, among which 90 patients were included in cases (group-I). The inclusion criteria were patients presenting with ACS aged between 18 and 45 years. There were two control groups, including 34 patients with ACS (aged >45 years) in Group II and 33 healthy volunteers in Group III (aged 18–45 years). Baseline demographic details, risk factors, and angiographic profile of patients with ACS in each group were recorded and compared. Results: Mean age of Group I was 39.79 ± 5.15 years and of Group II was 59.74 ± 8.21 years. Smoking (P = 0.027) and family history of coronary artery disease (P = 0.022) were the significant risk factors of ACS in Group I. Compared to non-ST elevation myocardial infarction (16.7%), ST-elevation myocardial infarction (83.3%) was predominant among younger patients with ACS. Single-vessel disease was prevalent among younger patients (62.2%) as compared to older patients with ACS (41.20%). Conclusion: Younger patients with ACS exhibited a distinct clinical and angiographic profile compared to older patients with ACS.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"9 1","pages":"121 - 126"},"PeriodicalIF":0.1,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42982779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Context: The context of the study was venous thromboembolism (VTE) in coronavirus disease 2019 (COVID-19) patients. Aim: The purpose of the study was to understand the prevalence of thrombotic events (pulmonary embolism [PE] and deep-vein thrombosis [DVT]) and right ventricular (RV) dysfunction (RVD) in patients with COVID-19. Settings and Design: Retrospective observational study, Max Hospital, New Delhi, India. Materials and Methods: This study was undertaken in 504 diagnosed COVID-19 adult patients of both genders in the age groups (>40 years and 40 years) during the COVID first and second waves in India. The hospital EMR database of the admitted COVID patients was extracted. Based on the study criteria, the parameters assessed were: D-dimer, CTSS scoring, DVT, RVD, and nature of hospitalization. Statistical Analysis Used: Quantitative variables were expressed in terms of mean and standard deviation. The significance of the association between different variables was evaluated by the Chi-square test. The significance of the difference in age and CTSS score between different categories of PE and DVT was tested by the Student's t-test. Results: The mean age of the patients was 57.13 years. The mean D-dimer level was 502.95 ng/mL. A PE was reported in 101 patients. The severity of the lung involvement as assessed on computed tomography pulmonary angiography was predominant in the bilateral segmental branch (70%), with a mean CTSS score of 14.47, 7.37. DVT was reported in 48 (9.5%) patients. RVD was observed in 14 (2.8%) patients. A significant correlation was found between PE and hospitalization (83.2%, P = 0.003), CTSS (20.07%, P = 0.037, confidence interval 0.10–3.31), and DVT (33.7%, P = 0.001). The prevalence of PE (20.03%) and VTE was 6.7%. RVD was reported in 2.8% of the cases. Conclusion: Our study validates the increased risk of VTE in COVID-19 patients. These findings will be useful to researchers and medical practitioners caring for COVID-19 patients.
{"title":"Venous thromboembolism and cardiopulmonary involvement in Covid 2019 patients: A retrospective observational study","authors":"Vivek Kumar, Reena Anand, S. Dhir, B. Aggarwal","doi":"10.4103/jpcs.jpcs_24_23","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_24_23","url":null,"abstract":"Context: The context of the study was venous thromboembolism (VTE) in coronavirus disease 2019 (COVID-19) patients. Aim: The purpose of the study was to understand the prevalence of thrombotic events (pulmonary embolism [PE] and deep-vein thrombosis [DVT]) and right ventricular (RV) dysfunction (RVD) in patients with COVID-19. Settings and Design: Retrospective observational study, Max Hospital, New Delhi, India. Materials and Methods: This study was undertaken in 504 diagnosed COVID-19 adult patients of both genders in the age groups (>40 years and 40 years) during the COVID first and second waves in India. The hospital EMR database of the admitted COVID patients was extracted. Based on the study criteria, the parameters assessed were: D-dimer, CTSS scoring, DVT, RVD, and nature of hospitalization. Statistical Analysis Used: Quantitative variables were expressed in terms of mean and standard deviation. The significance of the association between different variables was evaluated by the Chi-square test. The significance of the difference in age and CTSS score between different categories of PE and DVT was tested by the Student's t-test. Results: The mean age of the patients was 57.13 years. The mean D-dimer level was 502.95 ng/mL. A PE was reported in 101 patients. The severity of the lung involvement as assessed on computed tomography pulmonary angiography was predominant in the bilateral segmental branch (70%), with a mean CTSS score of 14.47, 7.37. DVT was reported in 48 (9.5%) patients. RVD was observed in 14 (2.8%) patients. A significant correlation was found between PE and hospitalization (83.2%, P = 0.003), CTSS (20.07%, P = 0.037, confidence interval 0.10–3.31), and DVT (33.7%, P = 0.001). The prevalence of PE (20.03%) and VTE was 6.7%. RVD was reported in 2.8% of the cases. Conclusion: Our study validates the increased risk of VTE in COVID-19 patients. These findings will be useful to researchers and medical practitioners caring for COVID-19 patients.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"9 1","pages":"132 - 137"},"PeriodicalIF":0.1,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41489535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：