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Recall of posttraumatic stress disorder treatment information. 创伤后应激障碍治疗信息的回忆。
IF 2.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2026-01-14 DOI: 10.1002/jts.70047
Sadie E Larsen, Kathleen M Grubbs, Peter Grau, Emily Munoz, Jessica Hamblen

Research has shown that better recall for treatment information is related to improved adherence and outcomes in psychotherapy. There has been minimal research on whether patients are able to recall information about posttraumatic stress disorder (PTSD) treatment options. To address this gap, participants who screened positive for PTSD (N = 887) were provided with descriptions of seven treatment options and asked to recall each treatment's effectiveness and whether it was a trauma-focused talk therapy. Participants were also randomly assigned a treatment and asked to write a brief description of the treatment as if they were describing it to a loved one. Correlates of recall (educational attainment level, numeracy) were also assessed. The results revealed that recall for treatment effectiveness was under 50%. Participants' ability to accurately identify trauma-focused talk therapy was under 75%. Only 31.8% of participants described their assigned treatment accurately. These findings suggest that patients retain little information about treatment options and underscore the importance of using strategies to enhance patients' memory during psychoeducation and treatment planning.

研究表明,更好地回忆治疗信息与改善心理治疗的依从性和结果有关。关于患者是否能够回忆起创伤后应激障碍(PTSD)治疗方案的信息的研究很少。为了弥补这一差距,研究人员向PTSD筛查呈阳性的参与者(N = 887)提供了7种治疗方案的描述,并要求他们回忆每种治疗的效果,以及是否为创伤性谈话治疗。参与者还被随机分配了一种治疗方法,并被要求写下一份简短的治疗描述,就像他们向所爱的人描述一样。回忆的相关因素(教育程度、计算能力)也被评估。结果显示,治疗效果的召回率低于50%。参与者准确识别以创伤为重点的谈话治疗的能力低于75%。只有31.8%的参与者准确地描述了他们被分配的治疗方法。这些研究结果表明,患者对治疗方案的记忆很少,并强调了在心理教育和治疗计划中使用策略来增强患者记忆的重要性。
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引用次数: 0
Validation and standardization of the Childhood Trauma Screener among Romanian children, adolescents, and college students. 罗马尼亚儿童、青少年和大学生儿童创伤筛查的验证和标准化。
IF 2.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2026-01-09 DOI: 10.1002/jts.70038
Oana Alexandra David, Cristina Teodora Tomoiagă, Ioana Alexandra Iuga

Childhood trauma, defined as violence against individuals under 18 years of age, affects 1,000,000,000 children globally, with neglect being the most common form. Such trauma is linked to various mental health issues and poor emotional regulation. This study aimed to validate the Childhood Trauma Screener (CTS) in a sample of Romanian children, adolescents, and college students, utilizing data from two separate samples: 1,221 first-year college students and 216 children and adolescents aged 8-16 years. We assessed validity using bivariate correlations, reliability using Cronbach's alpha (.63-.75), and structure using confirmatory factor analyses. In the college student sample, higher childhood trauma scores were associated with lower self-compassion, rs = -.24--.29, p < .001, and reappraisal use, rs = -.10--.22, p < .001; higher suppression use for exposure to neglect, r = .16, p < .001, and overall trauma, r = -.11, p < .001; and more mental health difficulties, rs = .29-.31, p < .001. In the child and adolescent sample, higher childhood trauma scores were associated with increased emotional and behavioral difficulties, rs = .28-.45, p < .001, and poorer emotion regulation abilities, particularly lower emotion control and reduced emotional self-awareness, rs = .16-.43, p < .001. The results from both samples supported a two-factor model of abuse and neglect.

童年创伤被定义为针对18岁以下个人的暴力行为,影响着全球10亿儿童,而忽视是最常见的形式。这种创伤与各种心理健康问题和情绪调节不良有关。本研究旨在在罗马尼亚儿童、青少年和大学生样本中验证儿童创伤筛查(CTS),利用来自两个独立样本的数据:1,221名一年级大学生和216名8-16岁的儿童和青少年。我们使用双变量相关性评估效度,使用Cronbach's alpha(0.63 - 0.75)评估信度,使用验证性因子分析评估结构。在大学生样本中,较高的童年创伤得分与较低的自我同情相关,rs = - 0.24 - 0.29, p
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引用次数: 0
Precision prediction of posttraumatic stress disorder symptom surges: A pilot study integrating real-time daily data with supervised learning. 创伤后应激障碍症状激增的精确预测:一项整合实时日常数据和监督学习的试点研究。
IF 2.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-12-29 DOI: 10.1002/jts.70036
Jordan P Davis, John Prindle, Eric R Pedersen, Daniel Leightley, Bistra Dilkina, Emily Dworkin, Shaddy Saba, Praneeth Thota, Sriram Nuthi, Mark A Prince, Angeles Sedano

The application of machine learning algorithms to daily diary data represents a valuable tool for improving dynamic prediction of posttraumatic stress disorder (PTSD) symptom escalations. This prospective, intensive longitudinal study aimed to evaluate whether combining baseline (static) and daily diary (dynamic) predictors with machine learning can help forecast clinically significant PTSD symptom increases among veterans. Participants were 74 recently discharged U.S. veterans (Mage = 33.5 years) who completed twice-daily diary surveys for up to 87 days via a mobile app, yielding 4,307 diary days. The outcome was a binary indicator of clinically significant daily PTSD symptom increase (> 1.0 standard deviation above a participant's individual mean over the first 2 study weeks). Random forest models identified top predictors; LASSO regression estimated effect sizes among top predictors. Daily negative affect was the top predictive variable, OR = 1.33, retained in 100% of LASSO iterations. Daily depressed mood, OR = 1.35; anxious mood, OR = 1.15; and perceived stress, OR = 1.13, were also reliably retained. Variables involving alcohol, cannabis use, and baseline impulsivity were less robust but remained prominent predictors of PTSD symptom escalations. Post hoc interaction analyses showed that co-occurring high negative affect and anxiety yielded a > 55% probability of PTSD symptom escalation. The findings show that daily affective states, especially negative mood and stress, strongly predict PTSD symptom increases in veterans. Using machine learning and high-frequency tracking, advances in personalized, real-time PTSD care are possible. Findings support just-in-time interventions for when veterans need help most: in the moment.

将机器学习算法应用于日常日记数据是改进创伤后应激障碍(PTSD)症状升级动态预测的有价值的工具。这项前瞻性、深入的纵向研究旨在评估将基线(静态)和日常日记(动态)预测指标与机器学习相结合是否有助于预测退伍军人临床显著的PTSD症状增加。参与者是74名最近退伍的美国退伍军人(年龄为33.5岁),他们通过移动应用程序完成了为期87天的每日两次日记调查,共记录了4307个日记日。结果是临床显著的每日PTSD症状增加的二元指标(在前两周的研究中,比参与者的个体平均值高出1.0个标准差)。随机森林模型确定了顶级预测因子;LASSO回归估计了顶级预测因子的效应大小。每日负面情绪是最重要的预测变量,OR = 1.33,在100%的LASSO迭代中保留。每日抑郁情绪,OR = 1.35;焦虑情绪,OR = 1.15;和感知压力,OR = 1.13,也可靠地保留。包括酒精、大麻使用和基线冲动在内的变量不太可靠,但仍然是PTSD症状升级的重要预测因素。事后相互作用分析显示,同时发生的高负性情绪和焦虑产生了大约55%的PTSD症状升级的可能性。研究结果表明,日常情感状态,尤其是消极情绪和压力,强烈地预示着退伍军人PTSD症状的增加。利用机器学习和高频跟踪,个性化的、实时的创伤后应激障碍治疗成为可能。研究结果支持在退伍军人最需要帮助的时候进行及时干预:在当下。
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引用次数: 0
Indirect effects of Seeking Safety plus sertraline on alcohol use: The mediating role of reductions in posttraumatic stress disorder symptom severity. 寻求安全加舍曲林对酒精使用的间接影响:创伤后应激障碍症状严重程度降低的中介作用
IF 2.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-12-29 DOI: 10.1002/jts.70031
Lesia M Ruglass, Jordan A Gette, Antonio A Morgan-López, Ai Ye, Kathryn Z Smith, Skye Fitzpatrick, Teresa López-Castro, Lissette M Saavedra, Sonya B Norman, Therese K Killeen, Sudie E Back, Denise A Hien

Posttraumatic stress disorder (PTSD) symptoms and alcohol use frequently co-occur and are mutually reinforcing. Few studies have examined how changes in PTSD severity influence subsequent changes in alcohol use, particularly in the context of comorbidity treatments. This secondary analysis utilized data from a clinical trial comparing 12 weeks of Seeking Safety plus sertraline (SS+S) versus Seeking Safety plus placebo (SS+P) among individuals (N = 69) with co-occurring PTSD and alcohol use disorder. A mediational analysis, using a latent growth modeling framework from five points throughout treatment, was conducted to examine whether reductions in alcohol use were mediated by treatment-led (SS+S vs. SS+P) reductions in PTSD severity. Results revealed a nonsignificant treatment effect on PTSD severity reductions over time, Est. = -0.440. The link between PTSD severity reductions and reductions in alcohol use was significant, Est. = 0.644. Despite the nonsignificant path between treatment group and PTSD severity (and in the presence of bias correction for small sample size), the formal test of mediation was significant such that for participants in the SS+S group, alcohol use reductions were fully mediated by reductions in PTSD severity, Est. = -0.283. These findings suggest one of the mechanisms through which SS+S exerts its effects on alcohol use is through reductions in PTSD severity. Clinicians working within the SS treatment platform may consider augmenting their treatment plan with sertraline in collaboration with clients. Future research is necessary to understand how medication and behavioral therapies synergize over a treatment course to improve PTSD and alcohol use.

创伤后应激障碍(PTSD)症状和酒精使用经常同时发生,并且是相互加强的。很少有研究调查创伤后应激障碍严重程度的变化如何影响随后的酒精使用变化,特别是在共病治疗的背景下。这一次要分析利用了一项临床试验的数据,比较了在合并PTSD和酒精使用障碍的个体(N = 69)中,为期12周的Seeking Safety +舍曲林(SS+S)与Seeking Safety +安慰剂(SS+P)。在整个治疗过程中,使用从五个点开始的潜在增长模型框架进行中介分析,以检查酒精使用的减少是否由治疗主导的PTSD严重程度的降低(SS+S vs SS+P)介导。结果显示,随着时间的推移,治疗对PTSD严重程度的降低效果不显著,Est = -0.440。PTSD严重程度的降低和酒精使用的减少之间的联系是显著的,Est = 0.644。尽管治疗组和创伤后应激障碍严重程度之间的路径不显著(并且存在小样本量的偏倚校正),但中介的正式检验是显著的,因此对于SS+S组的参与者,酒精使用的减少完全被创伤后应激障碍严重程度的降低所介导,Est = -0.283。这些发现表明,SS+S对酒精使用的作用机制之一是通过降低创伤后应激障碍的严重程度。在SS治疗平台内工作的临床医生可以考虑与客户合作,用舍曲林增加他们的治疗计划。未来的研究有必要了解药物和行为疗法如何在治疗过程中协同作用,以改善PTSD和酒精使用。
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引用次数: 0
Posttraumatic cognitions after military sexual assault are more strongly associated with sexual risk-taking among male service members and veterans. 在男性服役人员和退伍军人中,军人性侵犯后的创伤后认知与性冒险的关系更为密切。
IF 2.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-12-29 DOI: 10.1002/jts.70034
Maya Bina N Vannini, Hallie S Tannahill, Rebecca K Blais

Military sexual assault (MSA) survivors are particularly likely to engage in sexual risk-taking, or sexual behaviors that may result in sexually transmitted infections or unintended pregnancy. Theory suggests that posttraumatic cognitions, including negative thoughts about the self, negative thoughts about the world, and self-blame, may be a salient factor related to sexual risk-taking in this population. Further, sex differences have been observed in both posttraumatic cognitions and sexual risk-taking. In this secondary analysis of web-based survey data collected from U.S. service members and veterans (N = 400, 50.0% male), we hypothesized that posttraumatic cognitions would be positively associated with sexual risk-taking and that sex would moderate this effect. The moderation model significantly predicted sexual risk-taking, R2 = .19, F(6, 391) = 15.60, p < .001, and the effect of posttraumatic cognitions on sexual risk-taking significantly differed by sex, B = 0.13 (SE = .05), p = .009, such that it was stronger for male survivors, B = 0.22 (SE = .03), p < .001, than female survivors, B = 0.09 (SE = .04), p = .019. Exploratory post hoc moderation analyses revealed a similar pattern for both negative thoughts about the self and self-blame, whereas negative thoughts about the world did not differ by sex. The results point to the potential utility of cognitive-based therapies in reducing sexual risk-taking after MSA, particularly among male survivors, and highlight the importance of investigating psychological and interpersonal outcomes in this population. This study provides a vital contribution to the small literature base regarding male MSA survivors.

军事性侵犯(MSA)的幸存者特别有可能从事冒险的性行为,或者可能导致性传播感染或意外怀孕的性行为。理论表明,创伤后认知,包括对自我的消极想法、对世界的消极想法和自责,可能是这一人群中与性冒险有关的一个显著因素。此外,在创伤后认知和性冒险方面也观察到性别差异。在对美国服役人员和退伍军人(N = 400, 50.0%男性)的网络调查数据的二次分析中,我们假设创伤后认知与性冒险呈正相关,而性行为会缓和这种影响。调节模型显著预测性冒险行为,R2 = 0.19, F(6,391) = 15.60, p
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引用次数: 0
Impact of an app-based early intervention for survivors of recent sexual assault on social functioning outcomes 基于应用程序的性侵幸存者早期干预对社会功能结果的影响。
IF 2.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-12-28 DOI: 10.1002/jts.70026
Emily R. Dworkin, Elizabeth Lehinger, Thomas O. Walton, Esther Howe, Carolina Ibarra

Many survivors of sexual assault experience both psychological effects and problems with social functioning. App-based interventions are a promising means to extend the reach of early interventions and, thereby, reduce the risk of psychopathology, but their impact on social functioning is unknown. This is an analysis of secondary social functioning outcomes from a pilot randomized clinical trial of a coached app–based early intervention (THRIVE) for survivors of unwanted sexual contact that occurred within the last 10 weeks. The THRIVE app involved daily cognitive behavioral activities targeting posttraumatic stress and alcohol misuse and as-needed relationally focused exercises; weekly phone coaching supported app use. Adult women (N = 41) with past-10-week unwanted sexual contact and elevated posttraumatic stress and heavy drinking were randomized to receive either the THRIVE app or a symptom monitoring app. Participants were invited to use their respective app daily for 21 days and attend weekly coaching calls. Self-report assessments tracked changes in outcomes from baseline to postintervention and 3-month follow-up. Relative to participants in the control condition, those in the intervention condition showed larger increases in perceived support from friends, d = 0.85, and decreases in conformity drinking motives, d = -0.81, at 3-month follow-up. The results suggest that THRIVE may be a promising strategy to improve social functioning in sexual assault survivors. Future research on THRIVE should examine the mechanisms of these changes.

许多性侵犯的幸存者经历了心理影响和社会功能问题。基于应用程序的干预是一种很有前途的手段,可以扩大早期干预的范围,从而降低精神病理的风险,但它们对社会功能的影响尚不清楚。本文分析了一项随机临床试验的次要社会功能结果,该试验是针对过去10周内发生的不受欢迎的性接触的幸存者进行的基于指导应用程序的早期干预(THRIVE)。THRIVE应用程序包括针对创伤后应激和酒精滥用的日常认知行为活动,以及根据需要进行的关系集中练习;每周电话辅导支持应用程序的使用。41名成年女性(N = 41)在过去10周内发生了不想要的性接触,创伤后应激加剧,酗酒,她们被随机分配到THRIVE应用程序或症状监测应用程序中。参与者被邀请在21天内每天使用各自的应用程序,并参加每周的辅导电话。自我报告评估跟踪了从基线到干预后和3个月随访的结果变化。在3个月的随访中,与对照组相比,干预组在朋友支持的感知上有较大的增加(d = 0.85),在从规性饮酒动机上有较大的减少(d = -0.81)。结果表明,THRIVE可能是一种很有前途的策略,可以改善性侵犯幸存者的社会功能。未来对THRIVE的研究应该检查这些变化的机制。
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引用次数: 0
Predicting externalizing symptom trajectories in U.S. National Guard recruits: The role of adverse childhood experiences. 预测美国国民警卫队新兵的外化症状轨迹:童年不良经历的作用。
IF 2.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-12-24 DOI: 10.1002/jts.70037
Ali F Sloan, Tristan Bron, Craig A Marquardt, Seth G Disner, Siamak Noorbaloochi, Melissa A Polusny, Jonathan D Schaefer

Adverse childhood experiences (ACEs) are strongly associated with increased risk of externalizing problems. Despite their prevalence in military populations, limited research links ACEs to longitudinal externalizing problem trajectories during military service transition. This study aimed to identify distinct trajectories of externalizing problems (deviant behavior, alcohol use, and drug use) in U.S. Army National Guard recruits and examine how baseline ACEs predict membership in higher-risk trajectories during the transition to military service. A longitudinal cohort of 707 Army National Guard recruits was assessed before basic combat training and at four follow-ups over 18 months. Growth mixture modeling was used to identify distinct trajectories for deviant behavior, alcohol use, and drug use, whereas logistic regression analyses were conducted to examine associations between baseline ACEs and trajectory group membership. For each domain, we identified distinct trajectory patterns beyond stable-low: decreasing-increasing and increasing-decreasing deviant behavior trajectories, stable-high and increasing alcohol use trajectories, and a variable drug-users trajectory. Relative to stable-low class membership, higher ACE scores were associated with increased odds of membership in the decreasing-increasing, OR = 1.26, 95% CI [1.12, 1.41], and increasing-decreasing, OR = 1.26, 95% CI [1.15, 1.37], deviant behavior; stable-high alcohol, OR = 1.13, 95% CI [1.03, 1.25]; and drug-users, OR = 1.19, 95% CI [1.11, 1.28], trajectories. Specific ACEs uniquely predicted higher-risk trajectories. These findings suggest that ACEs may have longitudinal effects on the unfolding of externalizing symptom trajectories among military recruits, highlighting the need to address preexisting developmental vulnerabilities when examining pathways to psychopathology during significant life transitions.

不良童年经历(ace)与外化问题的风险增加密切相关。尽管ace在军人群体中普遍存在,但有限的研究将其与兵役过渡期间的纵向外化问题轨迹联系起来。本研究旨在确定美国陆军国民警卫队新兵外化问题(异常行为、酒精使用和药物使用)的不同轨迹,并研究基线ace如何预测过渡到军队服役期间高风险轨迹的成员资格。707名陆军国民警卫队新兵的纵向队列在基本战斗训练之前进行了评估,并在18个月内进行了四次随访。生长混合模型用于识别异常行为、酒精使用和药物使用的不同轨迹,而逻辑回归分析用于检查基线ace与轨迹组成员之间的关联。对于每个领域,我们确定了不同的轨迹模式,而不是稳定-低:减少-增加和增加-减少的异常行为轨迹,稳定-高和增加的酒精使用轨迹,以及可变的吸毒者轨迹。相对于稳定-低等级的成员,较高的ACE分数与加入减少-增加(OR = 1.26, 95% CI[1.12, 1.41])和增加-减少(OR = 1.26, 95% CI[1.15, 1.37])异常行为的几率增加相关;稳定-高酒精,OR = 1.13, 95% CI [1.03, 1.25];和吸毒者的轨迹,OR = 1.19, 95% CI[1.11, 1.28]。特定的ace能独特地预测高风险轨迹。这些研究结果表明,ace可能对新兵外化症状轨迹的展开有纵向影响,强调在重大生活转变期间检查精神病理途径时需要解决先前存在的发展脆弱性。
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引用次数: 0
Posttraumatic stress disorder symptom change in youth after trauma-focused cognitive behavioral therapy: Insights from cross-sectional and cross-lagged panel network analysis. 以创伤为中心的认知行为治疗后青少年创伤后应激障碍症状的改变:来自横断面和交叉滞后面板网络分析的见解
IF 2.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-12-24 DOI: 10.1002/jts.70030
Qiyue Cai, Bingyu Xu, Sydni A J Basha, Sun-Kyung Lee, Stephen G West, Abigail H Gewirtz

Trauma-focused cognitive behavioral therapy (TF-CBT) is an evidence-based treatment widely used for youth experiencing symptoms related to posttraumatic stress disorder (PTSD). This study used both cross-sectional and cross-lagged panel network (CLPN) analyses to examine changes in PTSD symptom networks following TF-CBT and explore their clinical relevance. Using data from a statewide implementation of TF-CBT, we constructed PTSD symptom networks for 652 youth (Mage = 12.47 years, 57.5% girls, 21.9% youth of color) who completed TF-CBT and provided both pre- and posttreatment data. At pretreatment, central symptoms included detachment, psychological and physiological reactions, and negative cognitions. Although the overall connectivity between symptoms significantly increased after treatment, p = .003, the symptom structure remained stable. CLPN analyses identified symptoms with high predictive influence (out-expected influence [out-EI]: physiological reactions, negative emotional state, and diminished interests) and susceptibility to influence (in-EI: internal and external avoidance, nightmare, detachment). Pretreatment centrality, B = 0.07, p < .001, and in-EI, B = 0.72, p = .003, but not out-EI, B = -0.04, p = .633, were associated with larger overall pre-post symptom reductions, controlling for baseline symptom severity. Improvements in symptoms with high pretreatment centrality, B = 1.17, p = .011), and in-EI centrality, B = 0.34, p = .568, but not out-EI centrality, B = 0.34, p = .568, were related to posttreatment psychosocial functioning over and above peripheral symptoms. These results offer preliminary evidence on how symptoms change during treatment, providing insight for understanding change mechanisms of TF-CBT and further refining youth trauma treatment.

以创伤为中心的认知行为疗法(TF-CBT)是一种基于证据的治疗方法,广泛用于经历创伤后应激障碍(PTSD)相关症状的青少年。本研究采用横断面和交叉滞后面板网络(CLPN)分析来检查TF-CBT后PTSD症状网络的变化,并探讨其临床相关性。利用TF-CBT在全国范围内实施的数据,我们为652名完成TF-CBT的青少年(年龄为12.47岁,57.5%为女孩,21.9%为有色人种)构建了PTSD症状网络,并提供了治疗前后的数据。在预处理时,中心症状包括脱离、心理和生理反应以及消极认知。虽然治疗后症状间整体连通性显著提高(p = 0.003),但症状结构保持稳定。CLPN分析确定了具有高预测影响(预期外影响[外ei]:生理反应、消极情绪状态和兴趣减少)和影响易感性(内ei:内外回避、噩梦、脱离)的症状。预处理中心性,B = 0.07, p
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引用次数: 0
Cognition improvement in U.S. veterans undergoing treatment for posttraumatic stress disorder: Secondary analyses from a randomized controlled trial. 接受创伤后应激障碍治疗的美国退伍军人的认知改善:随机对照试验的二次分析。
IF 2.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-12-24 DOI: 10.1002/jts.70033
Zulkayda Mamat, Danielle C Mathersul, Peter J Bayley

Cognitive dysfunction is a hallmark of posttraumatic stress disorder (PTSD). Although treatments effectively reduce core PTSD symptoms, limited research has examined whether associated cognitive impairments improve following treatment. This study investigated cognitive changes in veterans receiving treatment for PTSD and explored the associations between cognitive improvement and PTSD symptom reduction. U.S. veterans (N = 85) with clinically significant PTSD symptoms were randomized to receive either cognitive processing therapy (CPT; n = 44) or Sudarshan Kriya yoga (SKY; n = 41) in a noninferiority trial. Cognitive function was assessed pre- and posttreatment using the Cambridge Neuropsychological Test Automated Battery. PTSD symptoms were assessed using the Clinician-Administered PTSD Scale (CAPS-5). Following treatment, participants showed significant improvements in episodic visual memory, d = 0.51, p < .001; motor learning, d = 0.57, p < .001; and visual sustained attention, d = 0.37, p = .005. There were no significant differences in cognitive improvement between the CPT and SKY groups. Changes in overall cognitive function were significantly correlated with PTSD symptom reductions across both treatment groups. Regardless of treatment, cognitive function improved alongside PTSD symptom reduction. These findings provide evidence that treating PTSD not only alleviates PTSD symptoms but may also improve associated cognitive function.

认知功能障碍是创伤后应激障碍(PTSD)的标志。虽然治疗有效地减轻了核心创伤后应激障碍症状,但有限的研究已经检查了相关的认知障碍是否在治疗后得到改善。本研究调查了接受PTSD治疗的退伍军人的认知变化,并探讨了认知改善与PTSD症状减轻之间的关系。在一项非效性试验中,具有临床显著PTSD症状的美国退伍军人(N = 85)随机接受认知加工疗法(CPT, N = 44)或苏达山克里亚瑜伽(SKY, N = 41)。认知功能在治疗前和治疗后使用剑桥神经心理测试自动化电池进行评估。PTSD症状采用临床应用PTSD量表(CAPS-5)进行评估。治疗后,参与者在情景视觉记忆方面表现出显著改善,d = 0.51, p
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引用次数: 0
Feasibility randomized controlled trial of the mobile anger reduction intervention for veterans with posttraumatic stress disorder. 退伍军人创伤后应激障碍移动减怒干预的可行性随机对照试验。
IF 2.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-12-23 DOI: 10.1002/jts.70035
Kirsten H Dillon, Ryan Levi, Luke Nguyen, Jeffrey A Hertzberg, Eric B Elbogen, Patrick S Calhoun, Leslie A Morland, Jean C Beckham

Dysregulated anger is a prevalent concern for veterans with posttraumatic stress disorder (PTSD) and is associated with negative psychosocial outcomes. The tendency to perceive ambiguous interpersonal situations as hostile, also known as hostile interpretation bias, is associated with problematic anger. In the present study, we report on a feasibility randomized control trial (RCT) that sought to evaluate the feasibility and acceptability of the Mobile Anger Reduction Intervention (MARI) mobile application (app), which utilizes interpretation bias modification techniques to modify hostile interpretation bias in veterans with PTSD. Veterans with PTSD and elevated anger (N = 30) were randomly assigned to use either the MARI app (n = 16) or a mindfulness app (n = 14) for 4 weeks. Participants completed self-report questionnaires assessing anger, PTSD and depressive symptoms, suicidal ideation, and functional impairment at pretreatment, posttreatment, and 3-month follow-up assessments. The primary outcomes were acceptability and feasibility. Clinical outcomes were secondary. All a priori feasibility and acceptability benchmarks for the MARI app were met or exceeded, indicating that the app is an acceptable intervention for veterans with PTSD, and additional research of the intervention is feasible. Participants in the MARI condition demonstrated large reductions in hostile interpretation bias, d = -1.12, and moderate reductions in past-week anger, d = -0.65, and trait anger, d = -0.72, from pretreatment to posttreatment. Given the demonstrated feasibility and acceptability of the MARI app, in addition to the observed clinical improvements, a larger RCT of MARI for veterans with PTSD is warranted.

失调的愤怒是患有创伤后应激障碍(PTSD)的退伍军人普遍关注的问题,并与负面的社会心理结果有关。将模棱两可的人际关系情境视为敌意的倾向,也被称为敌意解释偏见,与问题性愤怒有关。在本研究中,我们报告了一项可行性随机对照试验(RCT),旨在评估移动愤怒减少干预(MARI)移动应用程序(app)的可行性和可接受性,该应用程序利用解释偏见修正技术来改变创伤后应激障碍退伍军人的敌对解释偏见。患有创伤后应激障碍和愤怒情绪升高的退伍军人(N = 30)被随机分配使用MARI应用程序(N = 16)或正念应用程序(N = 14) 4周。在治疗前、治疗后和3个月的随访评估中,参与者完成了评估愤怒、创伤后应激障碍和抑郁症状、自杀意念和功能障碍的自我报告问卷。主要结果为可接受性和可行性。临床结果是次要的。MARI应用程序的所有先验可行性和可接受性基准均达到或超过,表明该应用程序是一种可接受的创伤后应激障碍退伍军人干预措施,进一步的干预研究是可行的。从治疗前到治疗后,MARI条件下的参与者表现出敌意解释偏差的大幅减少,d = -1.12,过去一周的愤怒适度减少,d = -0.65,特质性愤怒适度减少,d = -0.72。鉴于MARI应用程序的可行性和可接受性,除了观察到的临床改善外,还需要对患有创伤后应激障碍的退伍军人进行更大的MARI随机对照试验。
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Journal of traumatic stress
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