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Transness is our salve: How trans identity facilitates healing from relational trauma with parental figures. 变性是我们的良药:变性身份如何促进与父母关系创伤的愈合。
IF 2.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2026-01-28 DOI: 10.1002/jts.70044
Joonwoo Lee, Sebastian Barr, Alberta M Gloria, Tonya J Roberts, Stephanie L Budge

Transgender and nonbinary (TNB) individuals experience high rates of relational trauma from parental figures, yet their pathways to healing remain underexplored. This qualitative study used constructivist grounded theory to develop a theoretical framework of how TNB adults heal from parental relational trauma. In-depth interviews with 15 racially and socioeconomically diverse U.S.-based TNB adults who experienced parental relational trauma generated the core phenomenon: "TNB identity and experiences initiate and sustain pathways of healing from parental relational trauma." This captures that rather than being a source of this trauma, recognizing and actualizing one's TNB identity is the central catalyst for healing from it. The healing process began with three conditions: (a) connecting with one's TNB identity/self, (b) gaining new clarity in parental harm through TNB-related parental harm, and (c) experiencing joy and oppression as TNB while lacking parental support. These conditions gave rise to strategies including (d) creating safer homes through queer/TNB chosen family, (e) committing to individual healing through therapy, and (f) reimagining life through ongoing actualization as TNB. The consequences of these strategies, in turn, created conditions that enabled subsequent strategies, including (g) attempting repair and intergenerational work with families of origin, (h) distancing as self-preservation, and (i) returning to TNB communities to sustain healing across generations. The consequences of these processes included personal, intergenerational, and collective healing. The study offers implications for research, clinical practice, and advocacy, calling for approaches that frame TNB identity not as a source of familial conflict but as a central resource for recovery.

跨性别和非二元性别(TNB)个体从父母身上经历的关系创伤率很高,但他们的康复途径仍未得到充分探索。本定性研究使用建构主义理论为TNB成人如何从父母关系创伤中治愈提供理论框架。对15名来自不同种族和社会经济背景、经历过父母关系创伤的美国TNB成年人的深入访谈产生了核心现象:“TNB的身份和经历开启并维持了从父母关系创伤中愈合的途径。”这表明,认识和实现一个人的TNB身份,不是这种创伤的根源,而是从创伤中康复的主要催化剂。治疗过程从三个条件开始:(a)与一个人的TNB身份/自我连接,(b)通过与TNB相关的父母伤害获得对父母伤害的新的清晰度,以及(c)在缺乏父母支持的情况下体验作为TNB的快乐和压迫。这些情况产生了一些策略,包括(d)通过选择酷儿/TNB的家庭创造更安全的家园,(e)通过治疗致力于个人康复,以及(f)通过不断实现TNB的身份来重新想象生活。这些策略的结果反过来又为后续的策略创造了条件,包括(g)尝试修复和与原生家庭的代际工作,(h)保持距离作为自我保护,以及(i)返回TNB社区以维持几代人的愈合。这些过程的结果包括个人的、代际的和集体的愈合。该研究为研究、临床实践和倡导提供了启示,呼吁采取方法,将TNB身份不是家庭冲突的来源,而是作为恢复的核心资源。
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引用次数: 0
Testing for stress sensitization to war exposure in adult Ukrainian refugees using latent classes of adverse childhood experiences. 使用不良童年经历的潜在类别测试成年乌克兰难民对战争暴露的压力敏化。
IF 2.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2026-01-23 DOI: 10.1002/jts.70048
Anne Agathe Pedersen, Karen-Inge Karstoft

Refugees of war are at high risk of exposure to war-related potentially traumatic events (PTEs) and the development of posttraumatic stress disorder (PTSD). The stress sensitization hypothesis posits that adverse childhood experiences (ACEs) can sensitize individuals to the stress of PTEs in adulthood. This study examined how ACEs might sensitize refugees to war exposure in a sample of 3,486 Ukrainian refugees. We identified four latent classes of ACEs: low exposure (57.4%), household dysfunction (21.5%), maltreatment (16.7%), and high exposure (4.4%). These classes were used in a logistic regression model to test for associations with PTSD, and an ACE Class x War Exposure interaction term was used to test for stress sensitization. Female gender, odds ratio (OR) = 1.99, 95% confidence interval (CI) [1.58, 2.49]; war exposure, OR = 1.55, 95% CI [1.30, 1.83]; and all ACE classes, ORs = 1.14-2.84, were significantly associated with PTSD, whereas we found no effects of stress sensitization. The lack of stress sensitization effects in our analysis might have been caused by uniformly high stress levels in this refugee sample, as well as the broadly defined war exposure measure we used. Future research should aim to assess whether certain types or intensities of exposure better reveal sensitization effects.

战争难民暴露于战争相关的潜在创伤事件(pte)和创伤后应激障碍(PTSD)发展的风险很高。应激致敏假说认为,不良童年经历(ace)可以使个体在成年后对pte的应激敏感。这项研究以3,486名乌克兰难民为样本,研究了ace如何使难民对战争暴露敏感。我们确定了四种潜在的ace类型:低暴露(57.4%)、家庭功能障碍(21.5%)、虐待(16.7%)和高暴露(4.4%)。这些类别在逻辑回归模型中用于测试与创伤后应激障碍的关联,并使用ACE x类战争暴露相互作用项来测试压力致敏性。女性,优势比(OR) = 1.99, 95%可信区间(CI) [1.58, 2.49];战争暴露,OR = 1.55, 95% CI [1.30, 1.83];所有ACE等级(or = 1.14-2.84)与PTSD显著相关,而我们未发现应激致敏的影响。在我们的分析中,缺乏压力致敏效应可能是由于这个难民样本中统一的高压力水平,以及我们使用的广泛定义的战争暴露测量。未来的研究应旨在评估某些类型或强度的暴露是否能更好地揭示致敏效应。
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引用次数: 0
Effectiveness of massed cognitive processing therapy for posttraumatic stress disorder: A retrospective analysis. 大规模认知加工治疗创伤后应激障碍的有效性:回顾性分析。
IF 2.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2026-01-19 DOI: 10.1002/jts.70045
Lara Baez, Jennifer Huberty, Jacqlyn Yourell, Courtney Jewell, Eric Lin, Debra Kaysen, Lashauna Cutts, Sofia Noori, Isobel Rosenthal, Kathleen Chard

Trauma exposure can lead to posttraumatic stress disorder (PTSD), a condition with significant individual and societal costs. Yet, access to evidence-based PTSD treatment, such as cognitive processing therapy (CPT), remains limited. Delivering CPT on an accelerated (i.e., massed) schedule via telehealth could increase access while preserving effectiveness. This study aimed to evaluate changes in PTSD, anxiety, and depressive symptoms over the course of virtual massed CPT delivered by a commercial virtual trauma clinic. The sample included adult patients with clinician‑diagnosed PTSD who completed 3 or more telehealth CPT sessions per week. PTSD, anxiety, and depressive symptoms were assessed at intake, discharge, and 30 and 90 days postdischarge. Paired t tests compared symptoms from intake to discharge; linear mixed‑effects models examined symptom trajectories over time. Analyses included 148 patients. Large effect sizes were observed for improvements in PTSD (ΔM = 39.00), d = 2.94; anxiety (ΔM = 8.90), d = 1.79; and depressive symptoms (ΔM = 8.23), d = 1.49, from intake to discharge. Symptom improvements for PTSD and depression were maintained at 30 and 90 days, whereas anxiety remained significantly improved from baseline at both time points but showed modest rebound between 30 and 90 days. Virtual massed CPT produced rapid, very large, and durable reductions in PTSD, depression, and anxiety. These findings support virtual massed CPT as a feasible option to expand access to evidence‑based PTSD care in community settings.

创伤暴露可导致创伤后应激障碍(PTSD),这是一种具有重大个人和社会成本的疾病。然而,以证据为基础的创伤后应激障碍治疗,如认知处理疗法(CPT),仍然有限。通过远程保健以加速(即大量)的时间表提供CPT可以在保持有效性的同时增加获取机会。本研究旨在评估一家商业虚拟创伤诊所在虚拟大规模CPT治疗过程中PTSD、焦虑和抑郁症状的变化。样本包括临床诊断为PTSD的成年患者,他们每周完成3次或更多的远程医疗CPT会议。在入院、出院以及出院后30和90天评估PTSD、焦虑和抑郁症状。配对t检验比较了从入院到出院的症状;线性混合效应模型检查了症状随时间的轨迹。分析纳入148例患者。PTSD的改善效果显著(ΔM = 39.00), d = 2.94;焦虑(ΔM = 8.90), d = 1.79;抑郁症状(ΔM = 8.23), d = 1.49。创伤后应激障碍和抑郁症的症状改善在30天和90天保持不变,而焦虑在两个时间点都比基线有显著改善,但在30天和90天之间出现温和反弹。虚拟大规模CPT在创伤后应激障碍、抑郁和焦虑方面产生了快速、非常大、持久的减少。这些发现支持虚拟大规模CPT作为一种可行的选择,以扩大在社区环境中获得基于证据的PTSD护理。
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引用次数: 0
Inclusion of sexual- and gender-minoritized individuals in randomized clinical trials of first-line treatments for posttraumatic stress disorder: A systematic literature review. 在创伤后应激障碍一线治疗的随机临床试验中纳入性和性别少数个体:系统的文献综述。
IF 2.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2026-01-19 DOI: 10.1002/jts.70043
Marley Warren, Lia J Smith, Sarah A Pridgen, Philip Held

Clinical treatment guidelines consistently recommend cognitive processing therapy (CPT), prolonged exposure (PE), and eye movement desensitization and reprocessing (EMDR) for posttraumatic stress disorder (PTSD). The efficacy of these interventions among sexual- and/or gender-minoritized (SGM) individuals has not been thoroughly investigated within randomized clinical trials (RCTs), despite known elevations in exposure to potentially traumatic events and PTSD symptoms relative to cisgender heterosexual individuals. We conducted a systematic literature review to examine the frequency with which SGM adults were enrolled in RCTs of CPT, PE, and EMDR and investigate these interventions' efficacy in reducing PTSD symptoms among SGM adults. We searched eight databases to identify RCTs published before August 7, 2025. The inclusion criteria were: written in English; RCT investigating the impact of CPT, PE, or EMDR on PTSD symptoms; utilized a standardized PTSD measure; reported PTSD outcome data; and enrolled individuals who were at least 18 years old. Literature reviews, case studies, protocols, and non-peer reviewed articles were excluded. Our search returned 1,821 unique records, with 519 meeting all eligibility criteria. Ten records reported sexual orientation and gender identity (SOGI) information and enrolled at least one SGM individual. Among studies that reported SOGI information, 12.1% and 2.2% of participants identified as sexual- and gender-minoritized, respectively. Results highlight that SOGI information is underreported in PTSD treatment research, posing significant challenges in determining the relative efficacy of these treatments and the extent to which SGM-affirmative adaptations are necessary. We offer recommendations for clinicians and researchers, including consistent reporting of full SOGI data.

临床治疗指南一致推荐认知加工疗法(CPT),长时间暴露(PE)和眼动脱敏和再加工(EMDR)治疗创伤后应激障碍(PTSD)。这些干预措施在性和/或性别少数(SGM)个体中的有效性尚未在随机临床试验(rct)中进行彻底调查,尽管已知相对于异性恋者,暴露于潜在创伤性事件和创伤后应激障碍症状的风险较高。我们进行了一项系统的文献综述,以检查SGM成人参加CPT、PE和EMDR的随机对照试验的频率,并研究这些干预措施在减轻SGM成人PTSD症状方面的疗效。我们检索了8个数据库,以确定2025年8月7日之前发表的rct。纳入标准为:以英文撰写;调查CPT、PE或EMDR对PTSD症状影响的随机对照试验;使用标准化的PTSD测量;报告的PTSD结果数据;并招募了至少18岁的人。文献综述、案例研究、协议和非同行评议的文章被排除在外。我们的搜索返回了1,821条唯一记录,其中519条符合所有资格标准。10份记录报告了性取向和性别认同(SOGI)信息,并登记了至少一名SGM个体。在报告SOGI信息的研究中,分别有12.1%和2.2%的参与者被确定为性少数和性别少数。结果强调,在PTSD治疗研究中,SOGI信息被低估了,这给确定这些治疗的相对疗效和sgm积极适应的程度带来了重大挑战。我们为临床医生和研究人员提供建议,包括一致报告完整的SOGI数据。
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引用次数: 0
The impact of yoga on posttraumatic stress disorder symptom clusters: A systematic review and meta-analysis of randomized controlled trials. 瑜伽对创伤后应激障碍症状群的影响:随机对照试验的系统回顾和荟萃分析。
IF 2.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2026-01-16 DOI: 10.1002/jts.70040
Sinead M Sinnott, Laura E Laumann, Katherine E Gnall, Crystal L Park, Yin Wu, Menaja Raja, Annmarie Khawand, Linda S Pescatello

Posttraumatic stress disorder (PTSD) is a disruptive, multifaceted disorder with an estimated lifetime prevalence of 8.3% in the U.S. population. Yoga has been shown to reduce PTSD symptoms overall, though little is known about its efficacy relative to specific PTSD symptom clusters. In this systematic review and meta-analysis, we examined the associations between yoga and symptom change in each DSM-5 PTSD symptom cluster. We hypothesized that yoga participation would be associated with significant reductions in each cluster, particularly alterations in arousal and reactivity/hyperarousal (AAR/H), relative to controls. We searched PubMed, PsycInfo, CINAHL, and SPORTDiscus for eligible studies published through October 2025. Studies that were yoga intervention randomized controlled trials, enrolled trauma survivors, and reported PTSD subscale scores were included. We computed standardized mean difference scores and used an NIH tool to assess risk of bias. In direct models (k = 9 studies), yoga led to small-medium reductions in intrusions, d = -0.31, p = .027, and total PTSD symptoms, d = -0.29, p = .030. When including age as a moderator, yoga also improved avoidance, d = -2.28, p = .003, and AAR/H symptoms, d = -1.92, p = .007. There was a substantial risk of bias across studies. Yoga showed the most robust effects for reducing intrusions and total PTSD symptoms, with efficacy in reducing avoidance and AAR/H symptoms when age was added as a moderator. Yoga's emphasis on mindfulness in the present moment may allow for attentional awareness that is protective against intrusions.

创伤后应激障碍(PTSD)是一种破坏性的、多方面的疾病,在美国人口中估计终生患病率为8.3%。瑜伽已被证明可以总体上减轻创伤后应激障碍的症状,尽管人们对其相对于特定的创伤后应激障碍症状群的功效知之甚少。在这项系统回顾和荟萃分析中,我们检查了瑜伽与DSM-5中每个PTSD症状群的症状改变之间的关系。我们假设,与对照组相比,瑜伽的参与将与每个集群的显著减少有关,特别是在唤醒和反应性/高唤醒(AAR/H)方面的改变。我们检索了PubMed、PsycInfo、CINAHL和SPORTDiscus,检索了2025年10月之前发表的符合条件的研究。研究包括瑜伽干预随机对照试验、招募创伤幸存者和报告的创伤后应激障碍亚量表得分。我们计算了标准化均差评分,并使用NIH工具评估偏倚风险。在直接模型(k = 9项研究)中,瑜伽导致了干扰的中小型减少,d = -0.31, p = 0.027,以及总PTSD症状,d = -0.29, p = 0.030。当将年龄作为调节因素时,瑜伽也改善了逃避,d = -2.28, p = 0.003,以及AAR/H症状,d = -1.92, p = 0.007。研究中存在很大的偏倚风险。瑜伽在减少干扰和总的PTSD症状方面表现出最强劲的效果,当年龄作为调节因素时,瑜伽在减少逃避和AAR/H症状方面也有效果。瑜伽强调当下的正念,这可能会让你的注意力不受干扰。
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引用次数: 0
Recall of posttraumatic stress disorder treatment information. 创伤后应激障碍治疗信息的回忆。
IF 2.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2026-01-14 DOI: 10.1002/jts.70047
Sadie E Larsen, Kathleen M Grubbs, Peter Grau, Emily Munoz, Jessica Hamblen

Research has shown that better recall for treatment information is related to improved adherence and outcomes in psychotherapy. There has been minimal research on whether patients are able to recall information about posttraumatic stress disorder (PTSD) treatment options. To address this gap, participants who screened positive for PTSD (N = 887) were provided with descriptions of seven treatment options and asked to recall each treatment's effectiveness and whether it was a trauma-focused talk therapy. Participants were also randomly assigned a treatment and asked to write a brief description of the treatment as if they were describing it to a loved one. Correlates of recall (educational attainment level, numeracy) were also assessed. The results revealed that recall for treatment effectiveness was under 50%. Participants' ability to accurately identify trauma-focused talk therapy was under 75%. Only 31.8% of participants described their assigned treatment accurately. These findings suggest that patients retain little information about treatment options and underscore the importance of using strategies to enhance patients' memory during psychoeducation and treatment planning.

研究表明,更好地回忆治疗信息与改善心理治疗的依从性和结果有关。关于患者是否能够回忆起创伤后应激障碍(PTSD)治疗方案的信息的研究很少。为了弥补这一差距,研究人员向PTSD筛查呈阳性的参与者(N = 887)提供了7种治疗方案的描述,并要求他们回忆每种治疗的效果,以及是否为创伤性谈话治疗。参与者还被随机分配了一种治疗方法,并被要求写下一份简短的治疗描述,就像他们向所爱的人描述一样。回忆的相关因素(教育程度、计算能力)也被评估。结果显示,治疗效果的召回率低于50%。参与者准确识别以创伤为重点的谈话治疗的能力低于75%。只有31.8%的参与者准确地描述了他们被分配的治疗方法。这些研究结果表明,患者对治疗方案的记忆很少,并强调了在心理教育和治疗计划中使用策略来增强患者记忆的重要性。
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引用次数: 0
Validation and standardization of the Childhood Trauma Screener among Romanian children, adolescents, and college students. 罗马尼亚儿童、青少年和大学生儿童创伤筛查的验证和标准化。
IF 2.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2026-01-09 DOI: 10.1002/jts.70038
Oana Alexandra David, Cristina Teodora Tomoiagă, Ioana Alexandra Iuga

Childhood trauma, defined as violence against individuals under 18 years of age, affects 1,000,000,000 children globally, with neglect being the most common form. Such trauma is linked to various mental health issues and poor emotional regulation. This study aimed to validate the Childhood Trauma Screener (CTS) in a sample of Romanian children, adolescents, and college students, utilizing data from two separate samples: 1,221 first-year college students and 216 children and adolescents aged 8-16 years. We assessed validity using bivariate correlations, reliability using Cronbach's alpha (.63-.75), and structure using confirmatory factor analyses. In the college student sample, higher childhood trauma scores were associated with lower self-compassion, rs = -.24--.29, p < .001, and reappraisal use, rs = -.10--.22, p < .001; higher suppression use for exposure to neglect, r = .16, p < .001, and overall trauma, r = -.11, p < .001; and more mental health difficulties, rs = .29-.31, p < .001. In the child and adolescent sample, higher childhood trauma scores were associated with increased emotional and behavioral difficulties, rs = .28-.45, p < .001, and poorer emotion regulation abilities, particularly lower emotion control and reduced emotional self-awareness, rs = .16-.43, p < .001. The results from both samples supported a two-factor model of abuse and neglect.

童年创伤被定义为针对18岁以下个人的暴力行为,影响着全球10亿儿童,而忽视是最常见的形式。这种创伤与各种心理健康问题和情绪调节不良有关。本研究旨在在罗马尼亚儿童、青少年和大学生样本中验证儿童创伤筛查(CTS),利用来自两个独立样本的数据:1,221名一年级大学生和216名8-16岁的儿童和青少年。我们使用双变量相关性评估效度,使用Cronbach's alpha(0.63 - 0.75)评估信度,使用验证性因子分析评估结构。在大学生样本中,较高的童年创伤得分与较低的自我同情相关,rs = - 0.24 - 0.29, p
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引用次数: 0
Precision prediction of posttraumatic stress disorder symptom surges: A pilot study integrating real-time daily data with supervised learning. 创伤后应激障碍症状激增的精确预测:一项整合实时日常数据和监督学习的试点研究。
IF 2.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-12-29 DOI: 10.1002/jts.70036
Jordan P Davis, John Prindle, Eric R Pedersen, Daniel Leightley, Bistra Dilkina, Emily Dworkin, Shaddy Saba, Praneeth Thota, Sriram Nuthi, Mark A Prince, Angeles Sedano

The application of machine learning algorithms to daily diary data represents a valuable tool for improving dynamic prediction of posttraumatic stress disorder (PTSD) symptom escalations. This prospective, intensive longitudinal study aimed to evaluate whether combining baseline (static) and daily diary (dynamic) predictors with machine learning can help forecast clinically significant PTSD symptom increases among veterans. Participants were 74 recently discharged U.S. veterans (Mage = 33.5 years) who completed twice-daily diary surveys for up to 87 days via a mobile app, yielding 4,307 diary days. The outcome was a binary indicator of clinically significant daily PTSD symptom increase (> 1.0 standard deviation above a participant's individual mean over the first 2 study weeks). Random forest models identified top predictors; LASSO regression estimated effect sizes among top predictors. Daily negative affect was the top predictive variable, OR = 1.33, retained in 100% of LASSO iterations. Daily depressed mood, OR = 1.35; anxious mood, OR = 1.15; and perceived stress, OR = 1.13, were also reliably retained. Variables involving alcohol, cannabis use, and baseline impulsivity were less robust but remained prominent predictors of PTSD symptom escalations. Post hoc interaction analyses showed that co-occurring high negative affect and anxiety yielded a > 55% probability of PTSD symptom escalation. The findings show that daily affective states, especially negative mood and stress, strongly predict PTSD symptom increases in veterans. Using machine learning and high-frequency tracking, advances in personalized, real-time PTSD care are possible. Findings support just-in-time interventions for when veterans need help most: in the moment.

将机器学习算法应用于日常日记数据是改进创伤后应激障碍(PTSD)症状升级动态预测的有价值的工具。这项前瞻性、深入的纵向研究旨在评估将基线(静态)和日常日记(动态)预测指标与机器学习相结合是否有助于预测退伍军人临床显著的PTSD症状增加。参与者是74名最近退伍的美国退伍军人(年龄为33.5岁),他们通过移动应用程序完成了为期87天的每日两次日记调查,共记录了4307个日记日。结果是临床显著的每日PTSD症状增加的二元指标(在前两周的研究中,比参与者的个体平均值高出1.0个标准差)。随机森林模型确定了顶级预测因子;LASSO回归估计了顶级预测因子的效应大小。每日负面情绪是最重要的预测变量,OR = 1.33,在100%的LASSO迭代中保留。每日抑郁情绪,OR = 1.35;焦虑情绪,OR = 1.15;和感知压力,OR = 1.13,也可靠地保留。包括酒精、大麻使用和基线冲动在内的变量不太可靠,但仍然是PTSD症状升级的重要预测因素。事后相互作用分析显示,同时发生的高负性情绪和焦虑产生了大约55%的PTSD症状升级的可能性。研究结果表明,日常情感状态,尤其是消极情绪和压力,强烈地预示着退伍军人PTSD症状的增加。利用机器学习和高频跟踪,个性化的、实时的创伤后应激障碍治疗成为可能。研究结果支持在退伍军人最需要帮助的时候进行及时干预:在当下。
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引用次数: 0
Indirect effects of Seeking Safety plus sertraline on alcohol use: The mediating role of reductions in posttraumatic stress disorder symptom severity. 寻求安全加舍曲林对酒精使用的间接影响:创伤后应激障碍症状严重程度降低的中介作用
IF 2.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-12-29 DOI: 10.1002/jts.70031
Lesia M Ruglass, Jordan A Gette, Antonio A Morgan-López, Ai Ye, Kathryn Z Smith, Skye Fitzpatrick, Teresa López-Castro, Lissette M Saavedra, Sonya B Norman, Therese K Killeen, Sudie E Back, Denise A Hien

Posttraumatic stress disorder (PTSD) symptoms and alcohol use frequently co-occur and are mutually reinforcing. Few studies have examined how changes in PTSD severity influence subsequent changes in alcohol use, particularly in the context of comorbidity treatments. This secondary analysis utilized data from a clinical trial comparing 12 weeks of Seeking Safety plus sertraline (SS+S) versus Seeking Safety plus placebo (SS+P) among individuals (N = 69) with co-occurring PTSD and alcohol use disorder. A mediational analysis, using a latent growth modeling framework from five points throughout treatment, was conducted to examine whether reductions in alcohol use were mediated by treatment-led (SS+S vs. SS+P) reductions in PTSD severity. Results revealed a nonsignificant treatment effect on PTSD severity reductions over time, Est. = -0.440. The link between PTSD severity reductions and reductions in alcohol use was significant, Est. = 0.644. Despite the nonsignificant path between treatment group and PTSD severity (and in the presence of bias correction for small sample size), the formal test of mediation was significant such that for participants in the SS+S group, alcohol use reductions were fully mediated by reductions in PTSD severity, Est. = -0.283. These findings suggest one of the mechanisms through which SS+S exerts its effects on alcohol use is through reductions in PTSD severity. Clinicians working within the SS treatment platform may consider augmenting their treatment plan with sertraline in collaboration with clients. Future research is necessary to understand how medication and behavioral therapies synergize over a treatment course to improve PTSD and alcohol use.

创伤后应激障碍(PTSD)症状和酒精使用经常同时发生,并且是相互加强的。很少有研究调查创伤后应激障碍严重程度的变化如何影响随后的酒精使用变化,特别是在共病治疗的背景下。这一次要分析利用了一项临床试验的数据,比较了在合并PTSD和酒精使用障碍的个体(N = 69)中,为期12周的Seeking Safety +舍曲林(SS+S)与Seeking Safety +安慰剂(SS+P)。在整个治疗过程中,使用从五个点开始的潜在增长模型框架进行中介分析,以检查酒精使用的减少是否由治疗主导的PTSD严重程度的降低(SS+S vs SS+P)介导。结果显示,随着时间的推移,治疗对PTSD严重程度的降低效果不显著,Est = -0.440。PTSD严重程度的降低和酒精使用的减少之间的联系是显著的,Est = 0.644。尽管治疗组和创伤后应激障碍严重程度之间的路径不显著(并且存在小样本量的偏倚校正),但中介的正式检验是显著的,因此对于SS+S组的参与者,酒精使用的减少完全被创伤后应激障碍严重程度的降低所介导,Est = -0.283。这些发现表明,SS+S对酒精使用的作用机制之一是通过降低创伤后应激障碍的严重程度。在SS治疗平台内工作的临床医生可以考虑与客户合作,用舍曲林增加他们的治疗计划。未来的研究有必要了解药物和行为疗法如何在治疗过程中协同作用,以改善PTSD和酒精使用。
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引用次数: 0
Posttraumatic cognitions after military sexual assault are more strongly associated with sexual risk-taking among male service members and veterans. 在男性服役人员和退伍军人中,军人性侵犯后的创伤后认知与性冒险的关系更为密切。
IF 2.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-12-29 DOI: 10.1002/jts.70034
Maya Bina N Vannini, Hallie S Tannahill, Rebecca K Blais

Military sexual assault (MSA) survivors are particularly likely to engage in sexual risk-taking, or sexual behaviors that may result in sexually transmitted infections or unintended pregnancy. Theory suggests that posttraumatic cognitions, including negative thoughts about the self, negative thoughts about the world, and self-blame, may be a salient factor related to sexual risk-taking in this population. Further, sex differences have been observed in both posttraumatic cognitions and sexual risk-taking. In this secondary analysis of web-based survey data collected from U.S. service members and veterans (N = 400, 50.0% male), we hypothesized that posttraumatic cognitions would be positively associated with sexual risk-taking and that sex would moderate this effect. The moderation model significantly predicted sexual risk-taking, R2 = .19, F(6, 391) = 15.60, p < .001, and the effect of posttraumatic cognitions on sexual risk-taking significantly differed by sex, B = 0.13 (SE = .05), p = .009, such that it was stronger for male survivors, B = 0.22 (SE = .03), p < .001, than female survivors, B = 0.09 (SE = .04), p = .019. Exploratory post hoc moderation analyses revealed a similar pattern for both negative thoughts about the self and self-blame, whereas negative thoughts about the world did not differ by sex. The results point to the potential utility of cognitive-based therapies in reducing sexual risk-taking after MSA, particularly among male survivors, and highlight the importance of investigating psychological and interpersonal outcomes in this population. This study provides a vital contribution to the small literature base regarding male MSA survivors.

军事性侵犯(MSA)的幸存者特别有可能从事冒险的性行为,或者可能导致性传播感染或意外怀孕的性行为。理论表明,创伤后认知,包括对自我的消极想法、对世界的消极想法和自责,可能是这一人群中与性冒险有关的一个显著因素。此外,在创伤后认知和性冒险方面也观察到性别差异。在对美国服役人员和退伍军人(N = 400, 50.0%男性)的网络调查数据的二次分析中,我们假设创伤后认知与性冒险呈正相关,而性行为会缓和这种影响。调节模型显著预测性冒险行为,R2 = 0.19, F(6,391) = 15.60, p
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引用次数: 0
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Journal of traumatic stress
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