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Assisting refugee survivors of torture and trauma: An existential perspective 帮助遭受酷刑和创伤的难民幸存者:存在主义视角。
IF 3.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-01-13 DOI: 10.1002/jts.23011
Pearl Fernandes, Paul Rhodes, Niels Buus

Consistent exposure to refugee narratives of trauma and torture can profoundly impact trauma therapists. This secondary analysis reanalyzed data from a narrative inquiry investigating the lived experiences of refugee trauma therapists. We aimed to explore emergent concerns through an existential lens to enrich understanding and provide additional insights into the lived experiences of these individuals. Participants in this purposive sample (N = 19) were therapists who had provided interventions to refugees for 2–34 years. Narrative construction, theory-guided data analysis, and memo writing were used to reanalyze data generated by semistructured interviews augmented by photo elicitation. The findings indicate that being forced to reevaluate familiar beliefs consequent to one's professional roles induced intense existential moments, described as “a dark night of the soul,” “the paradox of life and death,” “uncanny feelings of not being at home,” and “a falling.” Acknowledging the complexities of the field, an existential framework to assist refugee trauma therapists in metabolizing and living with the professional challenges they encounter instead of focusing on alleviating decontextualized symptoms of distress is recommended. Research to inform requirements of the space to enable refugee trauma therapists to share their concerns and facilitate transitions toward more authentic, nonevasive sense of “being-in-the-world” is suggested.

持续接触难民关于创伤和酷刑的叙述会对创伤治疗师产生深远影响。这项二次分析重新分析了一项调查难民创伤治疗师生活经历的叙事调查中的数据。我们旨在通过存在主义视角探索新出现的问题,以丰富对这些人生活经历的理解并提供更多的见解。这个有目的性的样本(N = 19)中的参与者都是曾为难民提供过 2-34 年干预服务的治疗师。研究采用了叙事建构、理论指导下的数据分析和备忘录写作等方法,重新分析了通过半结构式访谈和照片诱导获得的数据。研究结果表明,因职业角色而被迫重新评估自己所熟悉的信念会引发强烈的存在感,被描述为 "灵魂的黑夜"、"生与死的悖论"、"不在家的奇怪感觉 "和 "坠落"。考虑到这一领域的复杂性,建议制定一个存在主义框架,以帮助难民创伤治疗师新陈代谢,应对他们所遇到的专业挑战,而不是专注于缓解非语境化的痛苦症状。建议开展研究,以了解对空间的要求,使难民创伤治疗师能够分享他们的关切,并促进向更真实、无侵扰的 "存在于世界中 "的感觉过渡。
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引用次数: 0
A network analysis of Hurricane Maria–related traumatic stress and substance use among Puerto Rican youth 对波多黎各青少年与飓风玛丽亚有关的创伤压力和药物使用情况进行网络分析。
IF 3.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-01-10 DOI: 10.1002/jts.23008
Alejandro L. Vázquez, Cynthia M. Navarro Flores, Daniel K. Feinberg, Juan Carlos Gonzalez, John Young, Regan W. Stewart, Rosaura E. Orengo-Aguayo

Youth exposed to natural disasters are at risk of developing trauma-related symptoms as well as engaging in substance use. Although previous research has established associations between disaster-related stressors and substance use in youth, less has focused on how symptoms of posttraumatic stress disorder (PTSD) may underpin this association. The current study used network analysis to identify specific PTSD symptoms associated with substance use following a natural disaster. Participants were 91,732 youths (Grades 3–12) from across Puerto Rico who completed a needs assessment 5–9 months after Hurricane Maria made landfall in September 2017. We examined associations between PTSD symptoms and substance use, identified clusters of symptoms and bridges between them, and explored age- and binary gender–related differences in associations between specific PTSD symptoms and substance use. Analyses identified two symptom communities: (a) arousal and reactivity, negative alterations in cognition and mood, and substance use, and (b) avoidance and intrusion. Broader findings suggested that substance use was most strongly associated with PTSD-related irritability and angry outbursts among youths. Surrounding nodes explained only 4.1% of the variance in substance use, but this was higher among youths who reported not having a supportive adult, R2 = 8.5; friend, R2 = 7.9; or teacher/counselor, R2 = 7.7, in their life. The bridge symptoms of sleep disruption and physiological reactivity were identified as potentially critical intervention targets for disrupting PTSD symptom networks after a natural disaster. Implications for triaged mental health care following natural disasters and directions for future research are discussed.

遭受自然灾害的青少年有可能出现创伤相关症状并使用药物。尽管之前的研究已经证实了灾难相关压力源与青少年药物使用之间的关联,但较少关注创伤后应激障碍(PTSD)症状如何可能成为这种关联的基础。本研究利用网络分析法确定了与自然灾害后药物使用相关的特定创伤后应激障碍症状。参与者是波多黎各各地的 91732 名青少年(3-12 年级),他们在 2017 年 9 月飓风玛丽亚登陆后 5-9 个月完成了需求评估。我们研究了创伤后应激障碍症状和药物使用之间的关联,确定了症状群和症状之间的桥梁,并探讨了特定创伤后应激障碍症状和药物使用之间的年龄和二元性别相关差异。分析确定了两个症状群:(a)唤醒和反应性、认知和情绪的负面改变以及药物使用,以及(b)回避和侵入。更广泛的研究结果表明,药物使用与创伤后应激障碍相关的青少年易怒和愤怒爆发关系最为密切。周围节点只解释了 4.1%的药物使用变异,但在那些报告生活中没有支持他们的成年人(R2 = 8.5)、朋友(R2 = 7.9)或老师/辅导员(R2 = 7.7)的青少年中,这种解释率更高。睡眠中断和生理反应的桥接症状被认为是自然灾害后破坏创伤后应激障碍症状网络的潜在关键干预目标。本文讨论了自然灾害发生后分流心理健康护理的意义以及未来的研究方向。
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引用次数: 0
Effects of child trauma screening on trauma-informed multidisciplinary evaluation and service planning in the child welfare system 儿童创伤筛查对儿童福利系统中创伤知情多学科评估和服务规划的影响。
IF 3.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-01-09 DOI: 10.1002/jts.23001
Christian M. Connell, Ann Shun Swanson, Maegan Genovese, Jason M. Lang

Despite the prevalence of exposure to potentially traumatic events (PTEs) among children involved with the child welfare system (CWS), trauma screening is not yet a common practice. The purpose of this study was to assess the impact of embedding a formal trauma screening process in statewide multidisciplinary evaluations for CWS-involved youth. A retrospective record review was conducted with two random samples of cases reflecting both pre- and postimplementation of formal screening procedures (n = 70 preimplementation, n = 100 postimplementation). Findings from the record review indicate statistically significant improvements in the documentation of general, χ2(1, N = 170) = 18.8, p < .001, and specific, χ2(1, N = 170) = 10.7, p = .001, details of children's reactions associated with PTE exposure, as well as increases in providers’ recommendations, χ2(1, N = 170) = 18.1, p < .001, and referrals, χ2(1, N = 170) = 4.5, p = .034, for trauma-focused services. The early identification of trauma-related symptoms may help connect children more promptly to trauma-informed evidence-based interventions, which may avert or mitigate the long-term sequelae of child maltreatment and CWS involvement.

尽管参与儿童福利系统(CWS)的儿童普遍暴露于潜在创伤事件(PTEs),但创伤筛查尚未成为一种普遍做法。本研究的目的是评估在全州范围内对涉及儿童福利系统的青少年进行多学科评估时嵌入正式创伤筛查流程的影响。研究人员对两个随机样本的案例进行了回顾性记录审查,分别反映了正式筛查程序实施前和实施后的情况(实施前 n = 70,实施后 n = 100)。记录审查结果表明,在记录一般情况(χ2 (1, N = 170) = 18.8, p < .001)和具体情况(χ2 (1, N = 170) = 10.7, p = .001,与暴露于 PTE 相关的儿童反应细节,以及提供者建议(χ2 (1, N = 170) = 18.1,p < .001)和转介(χ2 (1, N = 170) = 4.5,p = .034)以创伤为重点的服务的增加。早期识别与创伤相关的症状可帮助儿童更及时地接受以创伤为基础的循证干预,从而避免或减轻儿童虐待和儿童福利机构参与的长期后遗症。
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引用次数: 0
A clinician's guide to the 2023 VA/DoD Clinical Practice Guideline for Management of Posttraumatic Stress Disorder and Acute Stress Disorder 2023 年退伍军人事务部/国防部《创伤后应激障碍和急性应激障碍管理临床实践指南》临床医师指南。
IF 3.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-01-07 DOI: 10.1002/jts.23013
Ariel J. Lang, Jessica L. Hamblen, Paul Holtzheimer, Ursula Kelly, Sonya B. Norman, David Riggs, Paula P. Schnurr, Ilse Wiechers

A clinical practice guideline (CPG) is a rigorously established set of recommendations based on currently available evidence about the efficacy, safety, acceptability, and feasibility of interventions to assist with clinical decision-making. The 2023 Department of Veterans Affairs /Department of Defense Clinical Practice Guideline for Management of Posttraumatic Stress Disorder and Acute Stress Disorder is described herein. The CPG recommendations are accompanied by a clinical algorithm, which incorporates principles of evidence-based practice, shared decision-making, and functional and contextual assessments of goals and outcomes. An overview of the CPG recommendations is combined with a discussion of questions that clinicians and patients may face in implementing the CPG and suggestions for how to effectively work with the CPG.

临床实践指南(CPG)是一套严格制定的建议,基于当前可用的有关干预措施的有效性、安全性、可接受性和可行性的证据,以协助临床决策。本文介绍了《2023 年退伍军人事务部/国防部创伤后应激障碍和急性应激障碍管理临床实践指南》。CPG 建议附有临床算法,其中包含循证实践原则、共同决策以及目标和结果的功能和背景评估。在概述 CPG 建议的同时,还讨论了临床医生和患者在实施 CPG 时可能面临的问题,以及如何有效利用 CPG 的建议。
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引用次数: 0
Differential correlates of prolonged grief and depression after bereavement in a population-based sample 以人口为基础的样本中丧亲后长期悲伤和抑郁的差异相关性。
IF 3.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2023-12-21 DOI: 10.1002/jts.22998
Arda Bağcaz, Cengiz Kılıç

Bereavement can lead to prolonged grief disorder (PGD) as well as episodes of major depression. Studies on the prevalence of PGD and its differences from postbereavement depression have not been conclusive. This study compared the correlates of depression and prolonged grief (PG) symptoms in a population-based random sample (N = 535) using the Beck Depression Inventory, Inventory of Complicated Grief–Revised, Anxiety Sensitivity Index (ASI), and Adult Separation Anxiety Questionnaire (ASAQ). Correlates of PG and depressive symptoms were examined using linear regression in 328 bereaved respondents. The prevalence of probable PGD based on PGD-2009 criteria was 3.0% among bereaved respondents and 1.9% in the total sample. PG was related to bereavement-related features including sex of the deceased, β = − .110, p = .026; time since loss, β = − .179, p = .001; the number of lifetime losses experienced, β = .157, p = .016; and perceived closeness with the deceased, β = .214, p < .001. Only lower income of the bereaved predicted depression, β = − .139, p = .018. In women, but not in men, the loss of a male family member (i.e., brother or son) was a significant predictor of PG symptoms, β = − .180, p = .006. The results confirm the qualitative distinction between depression and PG in a nonclinical sample and show that PG is mainly related to the intrinsic and extrinsic characteristics of the deceased or of death, whereas depression relates only to the characteristics of the bereaved person.

丧亲可以导致长期悲伤障碍(PGD)和重度抑郁症。关于 PGD 的患病率及其与丧亲后抑郁症的区别的研究尚未得出结论。本研究使用贝克抑郁量表(Beck Depression Inventory)、复杂悲伤量表(Inventory of Complicated Grief-Revised)、焦虑敏感指数(ASI)和成人分离焦虑问卷(ASAQ),比较了基于人群的随机抽样(N = 535)中抑郁症状和长期悲伤(PGD)症状的相关性。使用线性回归法对 328 名丧亲受访者的 PG 和抑郁症状进行了相关性研究。根据 PGD-2009 标准,丧亲受访者中可能患有 PGD 的比例为 3.0%,总样本中为 1.9%。PG与丧亲相关特征有关,包括逝者性别,β = - .110,p = .026;丧亲时间,β = - .179,p = .001;一生经历丧亲的次数,β = .157,p = .016;以及与逝者的亲密感,β = .214,p < .001。只有丧亲者收入较低才会导致抑郁,β = - .139,p = .018。在女性中,失去男性家庭成员(即兄弟或儿子)是预测 PG 症状的一个重要因素,β = - .180,p = .006。这些结果证实了在非临床样本中抑郁和 PG 的定性区别,并表明 PG 主要与死者或死亡的内在和外在特征有关,而抑郁仅与丧亲者的特征有关。
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引用次数: 0
Psychological distress and pain related to gynecologic exams among female survivors of sexual and physical violence: A systematic review 性暴力和身体暴力女性幸存者在妇科检查中的心理困扰和疼痛:系统综述。
IF 3.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2023-12-20 DOI: 10.1002/jts.23006
Jessica N. Coleman, Sarah S. Arthur, Rebecca A. Shelby

Gender-based violence is prevalent globally, yet the impacts of sexual and physical violence on women's experiences of routine gynecologic care are not well understood. The purpose of this systematic review of quantitative research is to describe (a) psychological distress and pain related to gynecologic exams among female survivors of sexual and physical violence and (b) differences in distress or pain between survivors and women without this history. Fourteen articles based on 12 discrete studies met the inclusion criteria. Studies were heterogeneous, with a moderate risk of bias; therefore, a descriptive summary approach was utilized rather than a meta-analytic approach. Synthesized results indicated that survivors of violence experience mild-to-severe levels of distress and mild-to-moderate levels of pain related to gynecologic exams. The findings suggest that survivors of sexual or physical violence experience higher levels of distress than women without this history (i.e., moderate to severe), and this difference was further accentuated among women with more severe posttraumatic stress symptoms (PTSS). Differences in pain by violence history and PTSS severity were not consistently observed, possibly due to a lack of variability in ratings and small sample sizes. Additional research is needed that bolsters the measurement of exam-related distress and pain, adjusts for confounding variables, and explores mechanisms by which sexual and physical violence impact care experiences. Further empirical work will be critical to developing interventions at the patient and provider levels to improve women's experiences of care.

基于性别的暴力在全球范围内普遍存在,但性暴力和身体暴力对女性常规妇科护理体验的影响却不甚了解。这篇定量研究的系统性综述旨在描述:(a) 性暴力和身体暴力女性幸存者与妇科检查相关的心理困扰和疼痛;(b) 幸存者与无此病史的女性在困扰或疼痛方面的差异。基于 12 项独立研究的 14 篇文章符合纳入标准。研究内容不尽相同,存在中度偏倚风险;因此,我们采用了描述性总结方法,而不是荟萃分析方法。综合结果表明,暴力幸存者在接受妇科检查时会感到轻度到严重程度的痛苦和轻度到中度程度的疼痛。研究结果表明,性暴力或身体暴力幸存者的痛苦程度高于无此病史的女性(即中度至重度),而这种差异在创伤后应激症状(PTSS)较严重的女性中更为突出。暴力史和创伤后应激障碍严重程度在疼痛方面的差异并没有被持续观察到,这可能是由于评分缺乏可变性和样本量较小的缘故。我们需要开展更多的研究来加强对检查相关痛苦和疼痛的测量,调整混杂变量,并探索性暴力和身体暴力影响护理体验的机制。进一步的实证工作对于在患者和提供者层面制定干预措施以改善妇女的护理体验至关重要。
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引用次数: 0
The PTSD Criterion A debate: A brief history, current status, and recommendations for moving forward 创伤后应激障碍标准 A 辩论:简史、现状及下一步建议。
IF 3.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2023-12-20 DOI: 10.1002/jts.23007
Brian P. Marx, Brittany Hall-Clark, Matthew J. Friedman, Paul Holtzheimer, Paula P. Schnurr

Posttraumatic stress disorder (PTSD) Criterion A, also known as the “stressor criterion,” has been a major source of debate ever since PTSD was added to the third edition of the Diagnostic and Statistical Manual for Mental Disorders (DSM) in 1980. Since then, the traumatic stress field has held an ongoing debate about how to best define Criterion A and the events that it covers. Because of the COVID-19 pandemic and recent race-based incidents, the Criterion A debate has been reinvigorated. In this paper, we review briefly the history of Criterion A and changes in its language across different editions of the DSM. We then describe the four main positions held by scholars involved in the Criterion A debate and carefully examine the support for those positions. We conclude by offering recommendations for moving forward.

创伤后应激障碍(PTSD)标准 A 也被称为 "应激源标准",自 1980 年《精神疾病诊断与统计手册》(DSM)第三版加入创伤后应激障碍标准 A 以来,该标准一直是争论的焦点。从那时起,创伤应激领域就一直在争论如何最好地定义标准 A 及其涵盖的事件。由于 COVID-19 大流行和最近发生的种族事件,标准 A 的争论重新活跃起来。在本文中,我们将简要回顾标准 A 的历史及其在不同版本 DSM 中的用语变化。然后,我们描述了参与 "标准 A "辩论的学者所持的四个主要立场,并仔细研究了这些立场的支持情况。最后,我们提出了前进的建议。
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引用次数: 0
Longitudinal associations among experiences of sexual assault, posttraumatic stress disorder symptoms, and heavy drinking in young adults 年轻成年人的性侵犯经历、创伤后应激障碍症状和酗酒之间的纵向联系。
IF 3.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2023-12-18 DOI: 10.1002/jts.23000
Eric R. Pedersen, Jordan P. Davis, Liv Canning, Joan S. Tucker, John Prindle, Rachana Seelam, Michael S. Dunbar, Daniel Siconolfi, Elizabeth J. D'Amico

Prior research with young adults has demonstrated clear associations between experiences of sexual assault, symptoms of posttraumatic stress disorder (PTSD), and alcohol use, but most studies have been cross-sectional or have not considered multiple theoretical pathways to understand these associations. Using six waves of data from a longitudinal cohort sample of 1,719 young adults, we examined associations among experiences of past-year sexual assault (i.e., rape, unwanted sexual touching, and physical intimidation in a sexual way), PTSD symptoms, and the frequency of binge drinking over time, allowing for the exploration of symptom-induced, interpersonal risk, and substance-induced pathways for male and female participants. For both male, βs = 2.84 to 6.55, and female participants, βs = 2.96 to 10.1, higher prior levels of PTSD symptoms were associated with larger increases in binge drinking over time. For female participants, higher prior levels of sexual assault were associated with larger increases in PTSD symptoms over time, βs = 3.48 to 4.25, whereas for male participants, higher prior levels of past-year binge drinking were associated with decreases in PTSD symptoms over time, βs = -2.75 to -0.53. Continued efforts are needed to prevent sexual assault among young adults and address PTSD symptoms among those who experience sexual assault. Interventions that target binge drinking are also needed for individuals who experience PTSD symptoms, especially young adults, to address potentially hazardous drinking before problems escalate and become chronic.

之前针对年轻人的研究表明,性侵犯经历、创伤后应激障碍(PTSD)症状和饮酒之间存在明显的关联,但大多数研究都是横断面研究,或者没有考虑多种理论途径来理解这些关联。我们利用一个由 1719 名年轻成年人组成的纵向队列样本的六次波次数据,研究了过去一年中性攻击(即强奸、不想要的性接触和性方面的身体恐吓)经历、创伤后应激障碍症状和随着时间推移的酗酒频率之间的关联,从而探讨了男性和女性参与者的症状诱导、人际风险和药物诱导途径。对于男性参与者(βs = 2.84 至 6.55)和女性参与者(βs = 2.96 至 10.1),先前较高水平的创伤后应激障碍症状与随着时间推移暴饮暴食的增加有关。对于女性参与者来说,先前遭受性侵犯的程度越高,随着时间的推移,创伤后应激障碍症状的增加幅度也越大,βs = 3.48 到 4.25;而对于男性参与者来说,过去一年暴饮暴食的程度越高,随着时间的推移,创伤后应激障碍症状的减少幅度也越大,βs = -2.75 到 -0.53。我们需要继续努力,预防年轻人遭受性侵犯,并解决遭受性侵犯者的创伤后应激障碍症状。对于出现创伤后应激障碍症状的人,尤其是青壮年,还需要采取针对暴饮的干预措施,在问题升级并演变成慢性之前解决潜在的危险饮酒问题。
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引用次数: 0
Treating a common comorbidity: Pain outcomes following a 3-week cognitive processing therapy–based intensive treatment for posttraumatic stress disorder address 治疗常见的合并症:基于认知处理疗法的创伤后应激障碍三周强化治疗后的疼痛疗效解决方法
IF 3.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2023-12-13 DOI: 10.1002/jts.22979
Merdijana Kovacevic, Mauricio Montes, Vanessa Tirone, Sarah Pridgen, Dale L. Smith, John W. Burns, Philip Held

Posttraumatic stress disorder (PTSD) commonly co-occurs with pain and has been implicated in the maintenance of chronic pain. However, limited research has examined whether intervening for PTSD can hinder or optimize treatment outcomes for co-occurring pain and PTSD. In the present study, we examined changes in pain, PTSD, and depressive symptoms among 125 veterans completing a 3-week cognitive processing therapy (CPT)–based intensive treatment program (ITP) for PTSD. We also explored whether pretreatment pain interference predicted changes in PTSD and depressive symptom severity and whether larger changes in pain interference over the course of treatment were associated with larger changes in PTSD and depressive symptom severity. Linear mixed models revealed that participants’ pain interference decreased throughout treatment, d = 0.15, p = .039. Higher levels of pretreatment pain interference were associated with higher PTSD, p = .001, and depressive symptom severity, p = .014, over time. Larger reductions in pain interference corresponded to more improvement in PTSD symptoms, β = −.03; p < .001, but not depressive symptoms. These findings indicate that ITPs for PTSD can reduce pain interferences, albeit to a small degree, and that reductions in pain interference can contribute to reductions in PTSD symptom severity. Future studies should examine which treatment components contribute to larger changes in symptom severity for veterans with co-occurring pain and PTSD.

创伤后应激障碍(PTSD)通常与疼痛并发,并与慢性疼痛的维持有关。然而,对创伤后应激障碍的干预是否会阻碍或优化并发疼痛和创伤后应激障碍的治疗效果的研究却很有限。在本研究中,我们考察了 125 名退伍军人在完成为期 3 周、基于认知加工疗法(CPT)的创伤后应激障碍强化治疗计划(ITP)后,疼痛、创伤后应激障碍和抑郁症状的变化情况。我们还探讨了治疗前的疼痛干扰是否能预测创伤后应激障碍和抑郁症状严重程度的变化,以及在治疗过程中疼痛干扰的较大变化是否与创伤后应激障碍和抑郁症状严重程度的较大变化有关。线性混合模型显示,参与者的疼痛干扰在整个治疗过程中都有所下降,d = 0.15,p = .039。随着时间的推移,治疗前较高的疼痛干扰水平与较高的创伤后应激障碍(p = .001)和抑郁症状严重程度(p = .014)相关。疼痛干扰程度降低越多,创伤后应激障碍症状改善越明显,β = -.03; p < .001,但抑郁症状改善不明显。这些研究结果表明,治疗创伤后应激障碍的ITP可以减少疼痛干扰,尽管程度很小,而且疼痛干扰的减少有助于创伤后应激障碍症状严重程度的减轻。未来的研究应检查哪些治疗内容有助于使同时患有疼痛和创伤后应激障碍的退伍军人的症状严重程度发生更大的变化。
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引用次数: 0
The impact of substance use on posttraumatic stress disorder symptoms and treatment discontinuation 使用药物对创伤后应激障碍症状和中断治疗的影响
IF 3.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2023-12-12 DOI: 10.1002/jts.23002
Brittany L. Stevenson, Jenny Y. Lee, David W. Oslin, Melissa A. Polusny, Shannon M. Kehle-Forbes

This study examined the impact of ongoing substance use during posttraumatic stress disorder (PTSD) and substance use disorder (SUD) treatment on PTSD symptoms and treatment discontinuation. The study represents a secondary analysis of U.S. military veterans (N = 183) who participated in a randomized clinical trial for the treatment of both PTSD and SUD. Veterans mostly identified as Black (53.8%) or White (41.9%) and male (92.4%). Substance use, PTSD symptoms, and treatment discontinuation were measured at 4-week intervals throughout treatment. Predictors were the percentage of days with alcohol, cannabis, and other substance use (primarily cocaine and opioids) and the average number of alcoholic drinks per drinking day. Outcomes were PTSD symptoms and treatment discontinuation at concurrent and prospective assessments. Multilevel models accounted for the nested structure of the longitudinal data. Alcohol, cannabis, and other substance use did not predict PTSD symptoms or treatment discontinuation prospectively. Concurrently, we observed that as a participant's percentage of drinking days increased by 34.7% (i.e., 1 standard deviation), PTSD symptoms during the same period were 0.07 standard deviations higher (i.e., 1 point on the PCL), B = 0.03, p = .033. No other substances were related to PTSD symptoms concurrently. The findings demonstrate that PTSD symptoms improved regardless of substance use during exposure-based PTSD and SUD treatment, and treatment discontinuation was not associated with substance use. This study suggests that substance use during treatment cannot directly explain the poorer treatment outcomes observed in the literature on comorbid PTSD/SUD compared to PTSD-only populations.

本研究探讨了创伤后应激障碍(PTSD)和药物使用障碍(SUD)治疗期间持续使用药物对创伤后应激障碍症状和治疗中断的影响。本研究对参加创伤后应激障碍和药物使用障碍随机临床试验的美国退伍军人(人数=183)进行了二次分析。退伍军人大多为黑人(53.8%)或白人(41.9%),男性(92.4%)。在整个治疗过程中,每隔 4 周对药物使用、创伤后应激障碍症状和治疗中断情况进行一次测量。预测因素包括使用酒精、大麻和其他药物(主要是可卡因和阿片类药物)的天数百分比,以及每个饮酒日的平均饮酒次数。结果是创伤后应激障碍症状以及在同期和前瞻性评估中的治疗中断。多层次模型考虑了纵向数据的嵌套结构。酒精、大麻和其他物质的使用并不能预测创伤后应激障碍症状或前瞻性治疗的中断。同时,我们观察到,当参与者的饮酒天数比例增加 34.7%(即 1 个标准差)时,同期的创伤后应激障碍症状会增加 0.07 个标准差(即在 PCL 上增加 1 分),B = 0.03,P = 0.033。没有其他物质同时与创伤后应激障碍症状相关。研究结果表明,在以暴露为基础的创伤后应激障碍和药物依赖治疗过程中,无论是否使用药物,创伤后应激障碍症状都会得到改善,而且治疗中断与使用药物无关。这项研究表明,与单纯创伤后应激障碍人群相比,在创伤后应激障碍/自闭症合并症治疗文献中观察到的治疗效果较差,而治疗期间使用药物并不能直接解释这一点。
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Journal of traumatic stress
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