Pub Date : 2023-08-31DOI: 10.36452/jmedscientiae.v2i2.2983
Kathleen Juanita Gunawan, I. W. Sumandyasa, Shelly Fransiska, Ninik Wibawani, Jason Jason
Antenatal care is the health service carried out by health workers to the mother during her pregnancy antenatal service standard compliance. When examined more deeply that the process of maternal death has a long journey so that prevention can be done since the antenatal care through education related to maternal health. Therefore, knowledge of pregnant women about antenatal care is very important because it will help reduce maternal and infant mortality .The purpose of this research is to know the relation of knowledge of mother with antenatal care number of visit of the Puskesmas Kecamatan Grogol Petamburan Jakarta Barat. This research conducted by method of cross sectional, the selection of samples with a consecutive sampling with 52 sample respondents. Data collection is carried out by filling a questionnaire made by researchers and is completed by respondents. Collected data is analyzed by chisquare test with significance level (⍺) 0.05. Stastical analysis.showed significant relationship between knowledge of antenatal care and the number of antenatal care visits (p=0,001)
{"title":"The Relationship Between Maternal Knowledge Level and the Number of Pregnancy Check-Up Visits at the Grogol Petamburan Community Health Center","authors":"Kathleen Juanita Gunawan, I. W. Sumandyasa, Shelly Fransiska, Ninik Wibawani, Jason Jason","doi":"10.36452/jmedscientiae.v2i2.2983","DOIUrl":"https://doi.org/10.36452/jmedscientiae.v2i2.2983","url":null,"abstract":"Antenatal care is the health service carried out by health workers to the mother during her pregnancy antenatal service standard compliance. When examined more deeply that the process of maternal death has a long journey so that prevention can be done since the antenatal care through education related to maternal health. Therefore, knowledge of pregnant women about antenatal care is very important because it will help reduce maternal and infant mortality .The purpose of this research is to know the relation of knowledge of mother with antenatal care number of visit of the Puskesmas Kecamatan Grogol Petamburan Jakarta Barat. This research conducted by method of cross sectional, the selection of samples with a consecutive sampling with 52 sample respondents. Data collection is carried out by filling a questionnaire made by researchers and is completed by respondents. Collected data is analyzed by chisquare test with significance level (⍺) 0.05. Stastical analysis.showed significant relationship between knowledge of antenatal care and the number of antenatal care visits (p=0,001)","PeriodicalId":175374,"journal":{"name":"Jurnal MedScientiae","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139347639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-31DOI: 10.36452/jmedscientiae.v2i2.2988
Indriani K Sumadikarya, Heriyanto Heriyanto, Dewi Iriani, Reagan Sanjaya Purnama
Pneumonia is the most problematic disease that happened in toddler that can lead to death. Data based on depkes, profil kesehatan 2010 population characteristic with the highest pneumonia happened in toddler (11,2%). The goal of this research is to know the relation between house environment and other factors in incident of pneumonia in Grogol petamburan, West Jakarta approach on 2020. The design of this study is cross sectional. Population sample used on this study is toddler who lived in Grogol petamburan, West Jakarta. The research subjects are 50 samples the technique used to gather samples using simple random sampling. The analysis used was Chi Square. the results shows that pneumonia as many as 36 people (72%) and not pneumonia as many as 14 people (28%). ASI exclusive (p=0.021), nutrient status (p=0.034), house environment (ventilation , sum of the people in the house)(p=0.017) these are the factors that have relation to cause pneumonia in toddler while age (p=0.970), immunization status (p=0.595), parents education (p=0.05), cigarette (p=0.503) don’t have any relation to cause pneumonia in toddler
{"title":"Pneumonia Incident in Toddler Related to House Environment and Other Factors","authors":"Indriani K Sumadikarya, Heriyanto Heriyanto, Dewi Iriani, Reagan Sanjaya Purnama","doi":"10.36452/jmedscientiae.v2i2.2988","DOIUrl":"https://doi.org/10.36452/jmedscientiae.v2i2.2988","url":null,"abstract":"Pneumonia is the most problematic disease that happened in toddler that can lead to death. Data based on depkes, profil kesehatan 2010 population characteristic with the highest pneumonia happened in toddler (11,2%). The goal of this research is to know the relation between house environment and other factors in incident of pneumonia in Grogol petamburan, West Jakarta approach on 2020. The design of this study is cross sectional. Population sample used on this study is toddler who lived in Grogol petamburan, West Jakarta. The research subjects are 50 samples the technique used to gather samples using simple random sampling. The analysis used was Chi Square. the results shows that pneumonia as many as 36 people (72%) and not pneumonia as many as 14 people (28%). ASI exclusive (p=0.021), nutrient status (p=0.034), house environment (ventilation , sum of the people in the house)(p=0.017) these are the factors that have relation to cause pneumonia in toddler while age (p=0.970), immunization status (p=0.595), parents education (p=0.05), cigarette (p=0.503) don’t have any relation to cause pneumonia in toddler","PeriodicalId":175374,"journal":{"name":"Jurnal MedScientiae","volume":"102 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139347532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-31DOI: 10.36452/jmedscientiae.v2i2.2987
A. T. Hutapea, Suryadi Susanto, Novita Anggraeni, Gracela Salurante
Hyperbilirubinemia is an increase in bilirubin levels >5 mg/dL which is characterized by the appearance of pathological jaundice. In the 2017 SKDI, the neonatal mortality rate was 19 per 1000 live births. The purpose of this study was to find out the prevalence of neonatal hyperbilirubinemia based on the blood group of the mother and the baby at Cengkareng General Hospital for the period January to March 2023. This research was conducted from January to March 2023 with an observational descriptive nature. This research was conducted at Cengkareng Hospital, West Jakarta. The study concluded that ABO incompatibility is not the only factor that contributes to hyperbilirubinemia in neonates. The results showed that 15 (41.7%) babies with hyperbilirubinemia came from mothers with blood type O, while the majority of babies who experienced hyperbilirubinemia were babies with blood type O, namely 16 (44.4%) babies. The majority of infants who experienced hyperbilirubinemia occurred in infants with blood group O and mothers with blood type O, namely 11 (30.6%), followed by infants with blood group A and mothers with blood type A, namely 4 (11.1%).
高胆红素血症是指胆红素水平升高超过 5 毫克/分升，以出现病理性黄疸为特征。在 2017 年的 SKDI 中，新生儿死亡率为每 1 000 例活产中有 19 例死亡。本研究的目的是根据 Cengkareng 综合医院 2023 年 1 月至 3 月期间母亲和婴儿的血型，了解新生儿高胆红素血症的发病率。本研究于 2023 年 1 月至 3 月进行，具有观察描述性质。研究在雅加达西部的 Cengkareng 医院进行。研究得出结论，ABO血型不相容并不是导致新生儿高胆红素血症的唯一因素。结果显示，15 名（41.7%）高胆红素血症婴儿的母亲是 O 型血，而大多数出现高胆红素血症的婴儿是 O 型血，即 16 名（44.4%）婴儿。大多数出现高胆红素血症的婴儿是 O 型血婴儿和 O 型血母亲，即 11 名（30.6%），其次是 A 型血婴儿和 A 型血母亲，即 4 名（11.1%）。
{"title":"Prevalence of Neonatal Hyperbilirubinemia Based on Mother's and Infant's Blood Group in Cengkareng Hospital","authors":"A. T. Hutapea, Suryadi Susanto, Novita Anggraeni, Gracela Salurante","doi":"10.36452/jmedscientiae.v2i2.2987","DOIUrl":"https://doi.org/10.36452/jmedscientiae.v2i2.2987","url":null,"abstract":"Hyperbilirubinemia is an increase in bilirubin levels >5 mg/dL which is characterized by the appearance of pathological jaundice. In the 2017 SKDI, the neonatal mortality rate was 19 per 1000 live births. The purpose of this study was to find out the prevalence of neonatal hyperbilirubinemia based on the blood group of the mother and the baby at Cengkareng General Hospital for the period January to March 2023. This research was conducted from January to March 2023 with an observational descriptive nature. This research was conducted at Cengkareng Hospital, West Jakarta. The study concluded that ABO incompatibility is not the only factor that contributes to hyperbilirubinemia in neonates. The results showed that 15 (41.7%) babies with hyperbilirubinemia came from mothers with blood type O, while the majority of babies who experienced hyperbilirubinemia were babies with blood type O, namely 16 (44.4%) babies. The majority of infants who experienced hyperbilirubinemia occurred in infants with blood group O and mothers with blood type O, namely 11 (30.6%), followed by infants with blood group A and mothers with blood type A, namely 4 (11.1%).","PeriodicalId":175374,"journal":{"name":"Jurnal MedScientiae","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139347547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-31DOI: 10.36452/jmedscientiae.v2i2.2982
Johannes Hudyono, Judin Purba Tanjung, D. M. R. Pasaribu, Inggrid Osya Far Far, R. Chairani
Not just obesity can cause a lot of trouble for physical health such as hypertension, dyslipidaemia, and diabetes, but also can cause problem for mental health such as depression. According to studies this can be an indirect cause that leads them to the depression state. Using analytic research, the aim in this study was to see whether there is a relationship between obesity and depression in medical students of Ukrida batch 2013 or not. Sample taken by purposive sampling technique and data retrieved by using PHQ-9 as a questionnaire to rate the students depression score and measure their body mass index to see their nutritional status. The result from the study were 21,5 % of total respondents with normal BMI and no depression, 28,5% with normal BMI and depression, 25,4% with obese BMI and no depression, and 24,6% obese BMI and depression. This study concluded that there was no significant relationship between obesity and depression in medical student of Ukrida batch 2013 (p value 0.380).
{"title":"The Relationship Between Obesity and Depression in Ukrida Medical Students","authors":"Johannes Hudyono, Judin Purba Tanjung, D. M. R. Pasaribu, Inggrid Osya Far Far, R. Chairani","doi":"10.36452/jmedscientiae.v2i2.2982","DOIUrl":"https://doi.org/10.36452/jmedscientiae.v2i2.2982","url":null,"abstract":"Not just obesity can cause a lot of trouble for physical health such as hypertension, dyslipidaemia, and diabetes, but also can cause problem for mental health such as depression. According to studies this can be an indirect cause that leads them to the depression state. Using analytic research, the aim in this study was to see whether there is a relationship between obesity and depression in medical students of Ukrida batch 2013 or not. Sample taken by purposive sampling technique and data retrieved by using PHQ-9 as a questionnaire to rate the students depression score and measure their body mass index to see their nutritional status. The result from the study were 21,5 % of total respondents with normal BMI and no depression, 28,5% with normal BMI and depression, 25,4% with obese BMI and no depression, and 24,6% obese BMI and depression. This study concluded that there was no significant relationship between obesity and depression in medical student of Ukrida batch 2013 (p value 0.380). \u0000 ","PeriodicalId":175374,"journal":{"name":"Jurnal MedScientiae","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130780009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-25DOI: 10.36452/jmedscientiae.v1i2.2951
Elly Tania, Andri Andri
Coronary heart disease (CHD) is a chronic disease that lasts a long time and requires long-term treatment, besides those physical conditions can also have an impact on a person's psychological condition, one of which is depression. However, it is possible that depression can also cause coronary heart disease in a person. Symptoms often overlap with cardiac symptoms, such as fatigue and insomnia (difficulty sleeping) which makes it difficult to diagnose depression in coronary heart disease patients. This study aims to determine the description of depression in coronary heart disease so that it can provide benefits in the form of knowledge about depression in coronary heart disease. The results of the data analyzed found the majority of respondents 93.3% had minimal or normal depression, 2.9% had mild depression, 1.9% had moderate depression and 1.9% had severe depression. The conclusion obtained from this study is that most of the respondents experienced minimal or normal depression, there was no difference between women and men, and there was no decrease in the quality of life of the respondents, such as feeling tired easily and having trouble sleeping.
{"title":"Description of Depression Level in Coronary Heart Disease Patients at RSPAD Gatot Soebroto in 2021","authors":"Elly Tania, Andri Andri","doi":"10.36452/jmedscientiae.v1i2.2951","DOIUrl":"https://doi.org/10.36452/jmedscientiae.v1i2.2951","url":null,"abstract":"Coronary heart disease (CHD) is a chronic disease that lasts a long time and requires long-term treatment, besides those physical conditions can also have an impact on a person's psychological condition, one of which is depression. However, it is possible that depression can also cause coronary heart disease in a person. Symptoms often overlap with cardiac symptoms, such as fatigue and insomnia (difficulty sleeping) which makes it difficult to diagnose depression in coronary heart disease patients. This study aims to determine the description of depression in coronary heart disease so that it can provide benefits in the form of knowledge about depression in coronary heart disease. The results of the data analyzed found the majority of respondents 93.3% had minimal or normal depression, 2.9% had mild depression, 1.9% had moderate depression and 1.9% had severe depression. The conclusion obtained from this study is that most of the respondents experienced minimal or normal depression, there was no difference between women and men, and there was no decrease in the quality of life of the respondents, such as feeling tired easily and having trouble sleeping.","PeriodicalId":175374,"journal":{"name":"Jurnal MedScientiae","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139349012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-25DOI: 10.36452/jmedscientiae.v1i2.2950
Citra Rencana Perangin-angin, Eva Oktavia, Chelna Feliarossa De Fretes
Coronavirus disease 2019 (COVID-19) is a disease that attacks the respiratory system with risk factors in the form of age, gender, and comorbid diseases. In addition, COVID-19 can affect oxygen saturation levels. Oxygen saturation is an indicator of oxygenation status by looking at the percentage of oxygen content in the arteries that binds to hemoglobin. The normal value for oxygen saturation is 95-100%. Objective to knowing the description of oxygen saturation of research respondents before treatment and before being discharged from UKRIDA Hospital which is influenced by age, gender and comorbid diseases. This study used a consecutive sampling method with a cross sectional design. There were 96 subjects who met the inclusion and exclusion criteria. Data collection was carried out using medical record data for the period January 1, 2021 to July 31, 2021. The results of data analysis using Chi-square with the results obtained that age and comorbid diseases have a relationship with changes in oxygen saturation levels (p-value <0.05). Meanwhile, gender had no relationship to changes oxygen saturation levels . There is a relationship between age and comorbid disease with changes in oxygen saturation levels before being discharged from UKRIDA Hospital with an average oxygen saturation of 97%.
{"title":"Overview of Oxygen Saturation in COVID-19 Patients Before Dispatching From UKRIDA Hospital in 2021","authors":"Citra Rencana Perangin-angin, Eva Oktavia, Chelna Feliarossa De Fretes","doi":"10.36452/jmedscientiae.v1i2.2950","DOIUrl":"https://doi.org/10.36452/jmedscientiae.v1i2.2950","url":null,"abstract":"Coronavirus disease 2019 (COVID-19) is a disease that attacks the respiratory system with risk factors in the form of age, gender, and comorbid diseases. In addition, COVID-19 can affect oxygen saturation levels. Oxygen saturation is an indicator of oxygenation status by looking at the percentage of oxygen content in the arteries that binds to hemoglobin. The normal value for oxygen saturation is 95-100%. Objective to knowing the description of oxygen saturation of research respondents before treatment and before being discharged from UKRIDA Hospital which is influenced by age, gender and comorbid diseases. This study used a consecutive sampling method with a cross sectional design. There were 96 subjects who met the inclusion and exclusion criteria. Data collection was carried out using medical record data for the period January 1, 2021 to July 31, 2021. The results of data analysis using Chi-square with the results obtained that age and comorbid diseases have a relationship with changes in oxygen saturation levels (p-value <0.05). Meanwhile, gender had no relationship to changes oxygen saturation levels . There is a relationship between age and comorbid disease with changes in oxygen saturation levels before being discharged from UKRIDA Hospital with an average oxygen saturation of 97%.","PeriodicalId":175374,"journal":{"name":"Jurnal MedScientiae","volume":"2013 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139349222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-25DOI: 10.36452/jmedscientiae.v2i2.2956
Wong Hendra Wijaya, Arini Astasari Widodo, Chearin Dea Sanfika
Acne vulgaris is a skin disease that attacks pilosebaceous follicles which can be either inflammatory or non-inflammatory lesion. One of the important factors causing acne vulgaris is androgen hormone. One of the hormonal therapies that can be given for acne vulgaris is spironolactone which has a function as an antiandrogen. The purpose of writing this literature review is to determine the effectiveness, mode of action, indications, contraindications, and side effects of spironolactone in the treatment of acne vulgaris. The method in making this final project is Literature Review. Literature searches were obtained using electronic databases such as Google Scholar, PubMed, Proquest, International Journal of Women's Dermatology, and NCBI. The keywords used were spironolactone, hormonal therapy, acne vulgaris, effectiveness of spironolactone for acne vulgaris. There are 10 supporting journals based on the suitability of topics in the last 10 years. The results showed that the administration of spironolactone for acne vulgaris proved to be effective with an average dose of 50-100 mg/day which resulted in 70-90% clinical improvement and caused minimal side effects. Spironolactone has good effectiveness and tolerability for alternative therapy of acne vulgaris in adult women and for patients who do not respond well to conventional therapy.
{"title":"Effectiveness of Spironolactone for Acne Vulgaris","authors":"Wong Hendra Wijaya, Arini Astasari Widodo, Chearin Dea Sanfika","doi":"10.36452/jmedscientiae.v2i2.2956","DOIUrl":"https://doi.org/10.36452/jmedscientiae.v2i2.2956","url":null,"abstract":"Acne vulgaris is a skin disease that attacks pilosebaceous follicles which can be either inflammatory or non-inflammatory lesion. One of the important factors causing acne vulgaris is androgen hormone. One of the hormonal therapies that can be given for acne vulgaris is spironolactone which has a function as an antiandrogen. The purpose of writing this literature review is to determine the effectiveness, mode of action, indications, contraindications, and side effects of spironolactone in the treatment of acne vulgaris. The method in making this final project is Literature Review. Literature searches were obtained using electronic databases such as Google Scholar, PubMed, Proquest, International Journal of Women's Dermatology, and NCBI. The keywords used were spironolactone, hormonal therapy, acne vulgaris, effectiveness of spironolactone for acne vulgaris. There are 10 supporting journals based on the suitability of topics in the last 10 years. The results showed that the administration of spironolactone for acne vulgaris proved to be effective with an average dose of 50-100 mg/day which resulted in 70-90% clinical improvement and caused minimal side effects. Spironolactone has good effectiveness and tolerability for alternative therapy of acne vulgaris in adult women and for patients who do not respond well to conventional therapy.","PeriodicalId":175374,"journal":{"name":"Jurnal MedScientiae","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139349041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-22DOI: 10.36452/jmedscientiae.v2i2.2798
Dea Amelia Glorie, Wiwi Kertadjaya, Reni Angeline
Latar belakang. Penyembuhan luka yang patologis dan pembentukan bekas luka patologis menimbulkan kerugian fungsional dan estetika. Keloid adalah bekas luka berlebihan yang tumbuh melewati batas luka aslinya yang merupakan kelainan fibroproliferatif. Keloid sulit untuk diobati karena sifat keloid yang rekuren dan terapi terhadap keloid yang masih belum sempurna dapat menyebabkan keloid semakin parah. Berdasarkan uraian diatas, studi literatur ini dibuat oleh penulis untuk menjelaskan tentang penyebab dan penanganan terhadap keloid. Metode. Artikel penelitian yang ditinjau berupa analytical review melalui data basePubMed. Hasil. Sebanyak 20 artikel penelitian terpilih yang sesuai dengan tujuan penulisan tinjauan pustaka ini. Kesimpulan.Penyebab utama keloid adalah trauma, cedera ataupun infeksi pada kulit. Monoterapi untuk keloid tidak disarankan karena tingkat kekambuhannya lebih tinggi dibandingkan dengan terapi kombinasi. Beberapa modalitas untuk pengobatan keloid adalah prosedur bedah, radioterapi, antitumor/antikanker, elektroporasi kalsium, kortikosteroid, tekanan magnetik intermitten, gel silikon, laser, Plasma Skin Regeration, dan penggunaan cryotherapy. Eksisi merupakan modalitas terapi yang memberikan pengurangan ukuran keloid secara instan, namun karena rekurensinya tinggi maka harus diberikan terapi lain sebagai terapi kombinasi, yaitu injeksi kortikosteroid ataupun radioterapi yang dapat mengurangi tingkat kekambuhan pasca eksisi.
{"title":"PENYEBAB DAN TATALAKSANA DALAM MENGATASI KELOID","authors":"Dea Amelia Glorie, Wiwi Kertadjaya, Reni Angeline","doi":"10.36452/jmedscientiae.v2i2.2798","DOIUrl":"https://doi.org/10.36452/jmedscientiae.v2i2.2798","url":null,"abstract":"Latar belakang. Penyembuhan luka yang patologis dan pembentukan bekas luka patologis menimbulkan kerugian fungsional dan estetika. Keloid adalah bekas luka berlebihan yang tumbuh melewati batas luka aslinya yang merupakan kelainan fibroproliferatif. Keloid sulit untuk diobati karena sifat keloid yang rekuren dan terapi terhadap keloid yang masih belum sempurna dapat menyebabkan keloid semakin parah. Berdasarkan uraian diatas, studi literatur ini dibuat oleh penulis untuk menjelaskan tentang penyebab dan penanganan terhadap keloid. Metode. Artikel penelitian yang ditinjau berupa analytical review melalui data basePubMed. Hasil. Sebanyak 20 artikel penelitian terpilih yang sesuai dengan tujuan penulisan tinjauan pustaka ini. Kesimpulan.Penyebab utama keloid adalah trauma, cedera ataupun infeksi pada kulit. Monoterapi untuk keloid tidak disarankan karena tingkat kekambuhannya lebih tinggi dibandingkan dengan terapi kombinasi. Beberapa modalitas untuk pengobatan keloid adalah prosedur bedah, radioterapi, antitumor/antikanker, elektroporasi kalsium, kortikosteroid, tekanan magnetik intermitten, gel silikon, laser, Plasma Skin Regeration, dan penggunaan cryotherapy. Eksisi merupakan modalitas terapi yang memberikan pengurangan ukuran keloid secara instan, namun karena rekurensinya tinggi maka harus diberikan terapi lain sebagai terapi kombinasi, yaitu injeksi kortikosteroid ataupun radioterapi yang dapat mengurangi tingkat kekambuhan pasca eksisi.","PeriodicalId":175374,"journal":{"name":"Jurnal MedScientiae","volume":"200 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115486598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-22DOI: 10.36452/jmedscientiae.v2i2.2907
Clara Valentia Josephine, Novelia Ratna Ury, S. Suparto
Obesitas morbid telah menjadi masalah kesehatan dunia. Sebanyak 55 juta orang dewasa mengalami obesitas morbid. Berbagai pilihan pengobatan ditawarkan, meliputi tindakan non-bedah dan bedah bariatric. Hasil pengobatan dinilai dari Indeks Massa Tubuh (IMT) pasien yang pada umumnya akan mengalami penurunan. Tujuan pembuatan literature review ini untuk mengetahui perbandingan penurunan IMT pasien obesitas morbid yang dilakukan bedah beriatrik dan non-bedah. Metode yang digunakan adalah kajian pustaka secara deskriptif terhadap delapan jurnal yang dipilih berdasarkan kriteria kelayakan. Berdasarkan tinjauan pustaka yang dikaji, diperoleh hasil dari total partisipan 1.903 orang yang diberikan intervensi bedah dan non bedah, presentase penurunan IMT pasien bedah bariatrik tertinggi pada tindakan RYGB yaitu 27.7%-62.9%, sedangkan terapi non-bedah yang hanya 5%. Selain itu, bedah bariatrik memiliki keunggulan yaitu penurunan berat badan dalam waktu yang lebih cepat dan bertahan dalam jangka panjang. Bedah bariatrik merupakan pilihan utama pada pasien dengan obesitas morbid.
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Pub Date : 2023-08-22DOI: 10.36452/jmedscientiae.v2i2.2818
Jenifer Putri Sianto, Rompu Roger Aruan, G. Widodo, Arini Astari Widodo
Psoriasis merupakan penyakit kulit inflamasi kronis yang dihubungkan dengan predisposisi genetik dan patogen autoimun. Penyakit ini ditandai dengan plak kemerahan dan sisik keperakan yang gatal hebat, bengkak, dan sakit sehingga menurunkan kualitas hidup penderitanya. Dalam beberapa tahun terakhir, cukup banyak terapi yang efektif dalam menangani psoriasis telah dikembangkan, meskipun demikian sebagian pasien tidak mengalami efek apapun ataupun kehilangan efek dari terapi-terapi tersebut dari waktu ke waktu. Tetapi saat ini telah ditemukan terapi baru yaitu Bimekizumab yang merupakan antibodi monoklonal dan diciptakan untuk menghambat IL-17A dan IL-17F secara bersamaan. Bimekizumab telah terbukti mereduksi skor PASI pasien psoriasis plak hingga 100 dengan efek samping minimal dan ringan tanpa imunogenisitas yang terdeteksi. Bimekizumab bekerja dengan jangka waktu yang lebih singkat dengan mencapai PASI 90 pada minggu ke-4 dan mempertahankan respon hingga minggu ke-52. Tinjauan pustaka ini bertujuan untuk membahas keunggulan bimekizumab dibandingkan dengan terapi psoriasis vulgaris lainnya.
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