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Systematic Review of 3D-Printed Ultrasound-able Models in Graduate Medical Education.
IF 2.1 4区 医学 Q2 ACOUSTICS Pub Date : 2024-12-03 DOI: 10.1002/jum.16624
Joshua D Krech, Taylor Wyatt, Derek J Harmon

This systematic review aimed to identify studies that have created ultrasound-able models for resident procedural training by means of 3D-printing techniques and examine their tissue specific properties. There were 456 articles identified from 3 databases, of which, 35 studies were assessed for eligibility, and 11 total studies were included. All qualitative studies showed improvements in procedural skills and 89% of the quantitative studies showed significant results. Studies that documented modeling price showed a 90% reduction in fabrication cost compared to commercial models. Three-dimensional-printed, ultrasound-able models have the potential to provide trainees with low-cost, high-fidelity training opportunities.

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引用次数: 0
Development of a Novel Nomogram Based on Ultrasonic Radiomics for Predicting Intrauterine Pregnancy After Frozen Embryo Transfer Cycle.
IF 2.1 4区 医学 Q2 ACOUSTICS Pub Date : 2024-11-29 DOI: 10.1002/jum.16625
Xin Yang, Yu Zheng, Xiaohui Li, Yuan Wu, Yao Fan, Wenzhi Lv, Zhen Zeng, Xiaoyan Xu

Objectives: This study aimed to develop a nomogram for predicting intrauterine pregnancy after an in vitro frozen embryo transfer cycle using endometrial ultrasound radiomics.

Methods: A total of 211 patients who underwent ultrasound examination on the day of endometrial transformation before the frozen embryo transfer cycle were enrolled. The patients were divided into an intrauterine pregnancy group and a pregnancy failure group based on ultrasound results. Clinical characteristics and radiomic features were analyzed using univariate and multivariate logistic regression analyses. A nomogram prediction model was established based on radiomic signatures and significant clinical factors. The model's robustness was assessed in training and external validation cohorts.

Results: Nine radiomic features were selected using least absolute shrinkage and selection operator (LASSO), and the radiomics score (Rad-score) was calculated as the sum of each feature multiplied by the nonzero coefficient from LASSO. The area under the curve (AUC) of the receiver operating characteristic (ROC) curve based on the Rad-score was 0.72, 0.65, and 0.69 in the training, validation, and combined cohorts, respectively. To improve diagnostic efficiency, the Rad-score was further integrated with clinical factors to form a novel predictive nomogram. The results indicated that the AUC increased to 0.81, 0.67, and 0.77 in the training, validation, and combined cohorts, respectively. Decision curve analysis showed that the radiomics nomogram was clinically useful.

Conclusion: The radiomics and clinical predictive nomogram can effectively predict intrauterine pregnancy after in vitro frozen embryo transfer and can be further applied in clinical strategy.

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引用次数: 0
Effectiveness of Comprehensive Video Datasets: Toward the Development of an Artificial Intelligence Model for Ultrasonography-Based Severity Diagnosis of Carpal Tunnel Syndrome. 综合视频数据集的有效性:开发基于超声波诊断腕管综合征严重程度的人工智能模型
IF 2.1 4区 医学 Q2 ACOUSTICS Pub Date : 2024-11-21 DOI: 10.1002/jum.16619
Tomohiko Waki, Yukina Sato, Kazuya Tsukamoto, Eriku Yamada, Akiko Yamamoto, Takuya Ibara, Toru Sasaki, Tomoyuki Kuroiwa, Akimoto Nimura, Yuta Sugiura, Koji Fujita, Toshitaka Yoshii

Objectives: Advances in diagnosing carpal tunnel syndrome (CTS) using ultrasonography (US) and artificial intelligence (AI) aim to replace nerve conduction studies. However, a method for accurate severity diagnosis remains unachieved. We explored the potential of comprehensive video data formats for constructing an effective model for diagnosing CTS severity.

Methods: We studied 75 individuals (52 with CTS) from 2019 to 2022, categorizing them into 3 groups based on disease severity. We recorded 132 US videos of carpal tunnel during finger movement. Features of the median nerve (MN) were extracted from automatically segmented US video frames, from which 3 datasets were created: a comprehensive video dataset with full information, a key metrics dataset, and an initial frame dataset with the least information. We compared the accuracy of machine learning algorithms for classifying CTS severity into 3 groups across these datasets using 63-fold cross-validation.

Results: The cross-sectional area of the MN correlated with severity (P < .05) but MN displacement did not. The algorithm using the comprehensive video dataset exhibited the highest sensitivity (1.00) and accuracy (0.75).

Conclusions: Our study demonstrated that utilizing comprehensive video data enables a more accurate US-based diagnosis of CTS severity. This underscores the value of capturing the patterns of MN deformation and movement, which cannot be captured by representative metrics such as medians or maximums. By further developing an AI model based on our findings, a simpler and painless method for assessing CTS severity can be achieved.

目的:利用超声波成像(US)和人工智能(AI)诊断腕管综合征(CTS)的进展旨在取代神经传导研究。然而,准确诊断严重程度的方法仍未实现。我们探索了综合视频数据格式在构建有效的 CTS 严重程度诊断模型方面的潜力:我们从 2019 年到 2022 年对 75 人(52 人患有 CTS)进行了研究,根据疾病严重程度将他们分为 3 组。我们录制了 132 个手指运动时的腕管 US 视频。我们从自动分割的 US 视频帧中提取了正中神经(MN)的特征,并从中创建了 3 个数据集:包含全部信息的综合视频数据集、关键指标数据集和包含最少信息的初始帧数据集。我们使用 63 次交叉验证,比较了机器学习算法在这些数据集上将 CTS 严重程度分为 3 组的准确性:结果:MN 的横截面积与严重程度相关(P 结论:MN 的横截面积与 CTS 的严重程度相关:我们的研究表明,利用全面的视频数据可以更准确地通过 US 诊断 CTS 的严重程度。这凸显了捕捉 MN 变形和运动模式的价值,而中位数或最大值等代表性指标无法捕捉到这些模式。在我们的研究成果基础上进一步开发人工智能模型,可以实现更简单、无痛的 CTS 严重程度评估方法。
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引用次数: 0
Ultrasound Characteristics of Keratoacanthoma: Differentiation From Well-Differentiated Cutaneous Squamous Cell Carcinoma. 角化棘皮瘤的超声特征:与分化良好的皮肤鳞状细胞癌鉴别
IF 2.1 4区 医学 Q2 ACOUSTICS Pub Date : 2024-11-20 DOI: 10.1002/jum.16622
Yan-Xuan Chen, Jian-Feng Liang, Ling-Li Xiao, De-Rui Zhan, Jing Wang

Objective: This study aims to describe the ultrasound characteristics of keratoacanthoma (KA), providing valuable insights for non-invasive diagnosis and differentiation from well-differentiated cutaneous squamous cell carcinoma (wcSCC).

Methods: Ultrasound characteristics of 16 KA and 13 wcSCC conformed by surgical pathology were retrospective analyzed.

Results: KA patients were younger (mean age 63.13 years) compared with wcSCC patients (mean age 76.23 years). Ultrasound characteristics revealed that KA lesions were generally smaller, more frequently domed-shaped (87.50 vs 38.46%), exophytic (93.75 vs 30.77%), and well-defined (93.75 vs 53.85%) compared with wcSCC. Both lesion types predominantly showed hypoechoic internal echoes and inhomogeneous echotexture. The prevalence of hyperechoic superficial area was notably high in both groups (93.75 vs 84.62%), precluding the reliable use of this feature as a discriminatory marker between these two distinct neoplastic entities. KA lesions were mostly confined to the epidermis and superficial dermis (87.50%), while wcSCC cases frequently infiltrated into the subcutaneous fat layer (84.62%). Color Doppler imaging demonstrated higher vascularity in wcSCC lesions, with 61.5% showing Grade 3 flow, compared with KA lesions, where 62.5% exhibited Grade 2 flow.

Conclusions: High-frequency ultrasound reveals distinct ultrasound characteristics differentiating KA from wcSCC, offering a promising non-invasive tool for preliminary diagnosis and treatment planning.

目的:本研究旨在描述角化棘皮瘤(KA)的超声特征,为无创诊断和与分化良好的皮肤鳞状细胞癌(wcSCC)的鉴别提供有价值的见解:方法:回顾性分析了 16 例 KA 和 13 例经手术病理确诊的 wcSCC 的超声特征:结果:与 wcSCC 患者(平均年龄 76.23 岁)相比,KA 患者更年轻(平均年龄 63.13 岁)。超声特征显示,与 wcSCC 相比,KA 病变一般较小,多呈圆顶形(87.50 vs 38.46%)、外生性(93.75 vs 30.77%)和界限清楚(93.75 vs 53.85%)。两种病变类型都主要表现为内部回声不足和回声纹理不均匀。高回声表层区域在两组中的发生率都很高(93.75% vs 84.62%),因此无法将这一特征作为区分这两种不同肿瘤实体的可靠标志。KA 病变大多局限于表皮和真皮浅层(87.50%),而 wcSCC 病例则经常浸润到皮下脂肪层(84.62%)。彩色多普勒成像显示,wcSCC 病变中的血管密度更高,61.5% 显示 3 级血流,而 KA 病变中 62.5% 显示 2 级血流:结论:高频超声显示了区分 KA 和 wcSCC 的独特超声特征,为初步诊断和治疗计划提供了一种前景广阔的无创工具。
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引用次数: 0
Lung Ultrasound Findings in Children With Asthma Exacerbations. 哮喘加重儿童的肺部超声波检查结果
IF 2.1 4区 医学 Q2 ACOUSTICS Pub Date : 2024-11-20 DOI: 10.1002/jum.16617
Robert M Hoffmann, Mark I Neuman, Michelle Du, Michael C Monuteaux, Andrew F Miller, Jeffrey T Neal, Kyle A Nelson, Cynthia A Gravel

Objective: We sought to assess whether the presence and extent of lung ultrasound (LUS) findings were associated with asthma exacerbation severity in children.

Methods: We enrolled a convenience sample of patients aged 5-18 years presenting with acute asthma exacerbation to a tertiary care pediatric emergency department. Severity of an asthma exacerbation (mild, moderate, severe) was assessed within 1 hour of the LUS using the Hospital Asthma Severity Score, a validated asthma assessment tool. LUS was performed by trained pediatric emergency providers. The presence of LUS findings (B-lines, consolidations, pleural effusion, and pleural line abnormalities) was assessed using a standardized criterion based on consensus guidelines.

Results: A total of 111 patients with a median age of 8 years (interquartile range 6-12) were enrolled. LUS was positive in 57% of patients. Pleural line abnormalities were observed in 34%, B-lines in 29%, consolidations <1 cm in 24%, and consolidations ≥1 cm in 7%. Patients with moderate and severe asthma exacerbations were more likely to have any B-lines (31% and 43%, respectively) than patients with mild exacerbations (12%; P = .021); however, the presence of ≥3 B-lines or confluent B-lines did not differ across severity groups. The presence of other findings did not differ based on asthma severity.

Conclusions: LUS findings are observed in a substantial portion of children presenting with asthma exacerbations. B-lines were the only LUS finding significantly associated with asthma severity, while lung consolidations <1 cm and >1 cm were not correlated with severity. These findings provide valuable information for the diagnostic use of LUS in pediatric patients with asthma exacerbation.

目的我们试图评估肺部超声波(LUS)检查结果的存在和范围是否与儿童哮喘加重的严重程度有关:我们选取了在一家三级医院儿科急诊科就诊的 5-18 岁哮喘急性加重患者作为样本。哮喘加重的严重程度(轻度、中度、重度)在LUS后1小时内使用医院哮喘严重程度评分(一种经过验证的哮喘评估工具)进行评估。LUS 由经过培训的儿科急诊医疗人员进行。LUS检查结果(B线、合并症、胸腔积液和胸膜线异常)采用基于共识指南的标准化标准进行评估:共纳入 111 名患者,中位年龄为 8 岁(四分位距为 6-12 岁)。57%的患者LUS呈阳性。34%的患者出现胸膜线异常,29%的患者出现B线异常,还有合并症:相当一部分哮喘加重的儿童可观察到 LUS 结果。B 线是唯一与哮喘严重程度显著相关的 LUS 发现,而 1 厘米的肺部合并症与哮喘严重程度无关。这些发现为哮喘加重的儿童患者使用 LUS 进行诊断提供了宝贵的信息。
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引用次数: 0
Model Based on Ultrasound Radiomics and Machine Learning to Preoperative Differentiation of Follicular Thyroid Neoplasm. 基于超声放射组学和机器学习的甲状腺滤泡性肿瘤术前分化模型
IF 2.1 4区 医学 Q2 ACOUSTICS Pub Date : 2024-11-18 DOI: 10.1002/jum.16620
Yiwen Deng, Qiao Zeng, Yu Zhao, Zhen Hu, Changmiao Zhan, Liangyun Guo, Binghuang Lai, Zhiping Huang, Zhiyong Fu, Chunquan Zhang

Objectives: To evaluate the value of radiomics based on ultrasonography in differentiating follicular thyroid carcinoma (FTC) and follicular thyroid adenoma (FTA) and construct a tool for preoperative noninvasive predicting FTC and FTA.

Methods: The clinical data and ultrasound images of 389 patients diagnosed with FTC or FTA postoperatively were retrospectively analyzed at 3 institutions from January 2017 to December 2023. Patients in our hospital were randomly assigned in a 7:3 ratio to training cohort and validation cohort. External test cohort consisted of data collected from other 2 hospitals. Radiomics features were used to develop models based on different machine learning classifiers. A combined model was developed combining radiomics features with clinical characteristics and a nomogram was depicted. The performance of the models was assessed by area under the receiver operating characteristic curve (AUC), calibration curve and decision curve.

Results: Radiomics model based on random forest showed best performance in discriminating FTC and FTA, with AUCs 0.880 (95% confidence interval [CI]: 0.8290-0.9308), 0.871 (95% CI: 0.7690-0.9734), and 0.821 (95% CI: 0.7036-0.9389) in training, validation, and test cohort, respectively. The combined model presented better efficacy comparing with clinical model and radiomics model, with AUCs 0.883 (95% CI: 0.8359-0.9295), 0.874 (95% CI: 0.7873-0.9615), and 0.876 (0.7809-0.9714) in training, validation, and test cohort, respectively. The calibration curves suggested good consistency and decision curves showed the highest overall clinical benefit for the combined model.

Conclusions: Ultrasound radiomics model based on random forest is feasible to differentiate FTC and FTA, and the combined model is an intuitively noninvasive tool for FTC and FTA preoperative identification.

研究目的评估基于超声造影的放射组学在鉴别甲状腺滤泡癌(FTC)和甲状腺滤泡腺瘤(FTA)中的价值,并构建术前无创预测FTC和FTA的工具:回顾性分析了2017年1月至2023年12月期间3家机构389例术后诊断为FTC或FTA患者的临床数据和超声图像。本院患者按 7:3 的比例随机分配到训练队列和验证队列。外部测试队列由其他两家医院收集的数据组成。放射组学特征被用于开发基于不同机器学习分类器的模型。结合放射组学特征和临床特征建立了一个综合模型,并绘制了一个提名图。模型的性能通过接收者操作特征曲线下面积(AUC)、校准曲线和决策曲线进行评估:基于随机森林的放射组学模型在鉴别 FTC 和 FTA 方面表现最佳,在训练队列、验证队列和测试队列中的 AUC 分别为 0.880(95% 置信区间 [CI]:0.8290-0.9308)、0.871(95% CI:0.7690-0.9734)和 0.821(95% CI:0.7036-0.9389)。与临床模型和放射组学模型相比,联合模型具有更好的疗效,在训练队列、验证队列和测试队列中的AUC分别为0.883(95% CI:0.8359-0.9295)、0.874(95% CI:0.7873-0.9615)和0.876(0.7809-0.9714)。校准曲线显示出良好的一致性,而决策曲线则显示出组合模型的总体临床效益最高:结论:基于随机森林的超声放射组学模型可用于鉴别 FTC 和 FTA,该组合模型是一种直观无创的 FTC 和 FTA 术前鉴别工具。
{"title":"Model Based on Ultrasound Radiomics and Machine Learning to Preoperative Differentiation of Follicular Thyroid Neoplasm.","authors":"Yiwen Deng, Qiao Zeng, Yu Zhao, Zhen Hu, Changmiao Zhan, Liangyun Guo, Binghuang Lai, Zhiping Huang, Zhiyong Fu, Chunquan Zhang","doi":"10.1002/jum.16620","DOIUrl":"10.1002/jum.16620","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the value of radiomics based on ultrasonography in differentiating follicular thyroid carcinoma (FTC) and follicular thyroid adenoma (FTA) and construct a tool for preoperative noninvasive predicting FTC and FTA.</p><p><strong>Methods: </strong>The clinical data and ultrasound images of 389 patients diagnosed with FTC or FTA postoperatively were retrospectively analyzed at 3 institutions from January 2017 to December 2023. Patients in our hospital were randomly assigned in a 7:3 ratio to training cohort and validation cohort. External test cohort consisted of data collected from other 2 hospitals. Radiomics features were used to develop models based on different machine learning classifiers. A combined model was developed combining radiomics features with clinical characteristics and a nomogram was depicted. The performance of the models was assessed by area under the receiver operating characteristic curve (AUC), calibration curve and decision curve.</p><p><strong>Results: </strong>Radiomics model based on random forest showed best performance in discriminating FTC and FTA, with AUCs 0.880 (95% confidence interval [CI]: 0.8290-0.9308), 0.871 (95% CI: 0.7690-0.9734), and 0.821 (95% CI: 0.7036-0.9389) in training, validation, and test cohort, respectively. The combined model presented better efficacy comparing with clinical model and radiomics model, with AUCs 0.883 (95% CI: 0.8359-0.9295), 0.874 (95% CI: 0.7873-0.9615), and 0.876 (0.7809-0.9714) in training, validation, and test cohort, respectively. The calibration curves suggested good consistency and decision curves showed the highest overall clinical benefit for the combined model.</p><p><strong>Conclusions: </strong>Ultrasound radiomics model based on random forest is feasible to differentiate FTC and FTA, and the combined model is an intuitively noninvasive tool for FTC and FTA preoperative identification.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142647488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Size Differences of Breast Cancer and Benign Tumors Measured by Two-Dimensional Ultrasound and Contrast-Enhanced Ultrasound. 用二维超声波和对比增强超声波测量乳腺癌和良性肿瘤的大小差异。
IF 2.1 4区 医学 Q2 ACOUSTICS Pub Date : 2024-11-18 DOI: 10.1002/jum.16621
Hideaki Ishida, Hiroko Naganuma
{"title":"The Size Differences of Breast Cancer and Benign Tumors Measured by Two-Dimensional Ultrasound and Contrast-Enhanced Ultrasound.","authors":"Hideaki Ishida, Hiroko Naganuma","doi":"10.1002/jum.16621","DOIUrl":"https://doi.org/10.1002/jum.16621","url":null,"abstract":"","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142647507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitative Ultrasound Parameters as Predictors of Chemotherapy Toxicity in Lymphoma: A Novel Approach to Assessing Muscle Mass and Quality Based on Ultrasound Radiofrequency Signals. 作为淋巴瘤化疗毒性预测指标的定量超声参数:基于超声射频信号评估肌肉质量的新方法
IF 2.1 4区 医学 Q2 ACOUSTICS Pub Date : 2024-11-18 DOI: 10.1002/jum.16618
Yang Sun, Jianqiu Huang, Jinhua Shao, Jianwen Luo, Qiong He, Ligang Cui

Objectives: The aim of this study was to use quantitative ultrasound (QUS) parameters to assess the muscle mass and quality in patients with lymphoma. Additionally, the study aimed to investigate the relationship between these QUS parameters and post-chemotherapy myelosuppression.

Methods: The study cohort comprised 202 patients diagnosed with lymphoma (105 males, 97 females; mean age 57.0 ± 14.9 years). The skeletal muscle index (SMI) and mean skeletal muscle density (SMD) were measured on CT and used as the gold standards to evaluate low skeletal muscle mass and quality. The muscle thickness (MT) of the forearm flexor and extensor muscles was measured in both the relaxed and contracted states, while the normalized non-linear parameter B/A (MusQBOX.NLP) and normalized mean intensity (MusQBOX.NMI) were extracted from retained ultrasound radiofrequency signals. The correlations between the QUS parameters and grip strength were assessed. Models were constructed using these QUS parameters to predict low SMI and SMD, and to evaluate whether these factors were independently associated with post-chemotherapy myelosuppression.

Results: The MT in both the relaxed and contracted states exhibited the strongest correlations with grip strength, while the MusQBOX.NLP and MusQBOX.NMI were only weakly correlated with grip strength. Models incorporating QUS parameters to predict low SMI and SMD achieved high area under the receiver operating characteristic curve values. The MT, MusQBOX.NLP, and MusQBOX.NMI were independent factors associated with post-chemotherapy myelosuppression.

Conclusions: QUS parameters show promise in characterizing muscle strength, mass, and quality. They are also independent factors influencing post-chemotherapy myelosuppression.

研究目的本研究旨在使用定量超声(QUS)参数评估淋巴瘤患者的肌肉质量和品质。此外,研究还旨在探讨这些 QUS 参数与化疗后骨髓抑制之间的关系:研究对象包括 202 名淋巴瘤患者(男性 105 人,女性 97 人;平均年龄 57.0 ± 14.9 岁)。通过 CT 测量骨骼肌指数(SMI)和平均骨骼肌密度(SMD),并将其作为评估低骨骼肌质量和品质的金标准。测量了前臂屈肌和伸肌在放松和收缩状态下的肌肉厚度(MT),同时从保留的超声射频信号中提取了归一化非线性参数B/A(MusQBOX.NLP)和归一化平均强度(MusQBOX.NMI)。评估了 QUS 参数与握力之间的相关性。利用这些 QUS 参数构建了预测低 SMI 和 SMD 的模型,并评估这些因素是否与化疗后骨髓抑制独立相关:结果:放松和收缩状态下的MT与握力的相关性最强,而MusQBOX.NLP和MusQBOX.NMI与握力的相关性较弱。结合 QUS 参数预测低 SMI 和 SMD 的模型达到了较高的接收器操作特征曲线下面积值。MT、MusQBOX.NLP和MusQBOX.NMI是与化疗后骨髓抑制相关的独立因素:结论:QUS 参数在描述肌肉强度、质量和品质方面显示出前景。结论:QUS参数在描述肌肉强度、质量和品质方面显示出前景,它们也是影响化疗后骨髓抑制的独立因素。
{"title":"Quantitative Ultrasound Parameters as Predictors of Chemotherapy Toxicity in Lymphoma: A Novel Approach to Assessing Muscle Mass and Quality Based on Ultrasound Radiofrequency Signals.","authors":"Yang Sun, Jianqiu Huang, Jinhua Shao, Jianwen Luo, Qiong He, Ligang Cui","doi":"10.1002/jum.16618","DOIUrl":"https://doi.org/10.1002/jum.16618","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to use quantitative ultrasound (QUS) parameters to assess the muscle mass and quality in patients with lymphoma. Additionally, the study aimed to investigate the relationship between these QUS parameters and post-chemotherapy myelosuppression.</p><p><strong>Methods: </strong>The study cohort comprised 202 patients diagnosed with lymphoma (105 males, 97 females; mean age 57.0 ± 14.9 years). The skeletal muscle index (SMI) and mean skeletal muscle density (SMD) were measured on CT and used as the gold standards to evaluate low skeletal muscle mass and quality. The muscle thickness (MT) of the forearm flexor and extensor muscles was measured in both the relaxed and contracted states, while the normalized non-linear parameter B/A (MusQBOX.NLP) and normalized mean intensity (MusQBOX.NMI) were extracted from retained ultrasound radiofrequency signals. The correlations between the QUS parameters and grip strength were assessed. Models were constructed using these QUS parameters to predict low SMI and SMD, and to evaluate whether these factors were independently associated with post-chemotherapy myelosuppression.</p><p><strong>Results: </strong>The MT in both the relaxed and contracted states exhibited the strongest correlations with grip strength, while the MusQBOX.NLP and MusQBOX.NMI were only weakly correlated with grip strength. Models incorporating QUS parameters to predict low SMI and SMD achieved high area under the receiver operating characteristic curve values. The MT, MusQBOX.NLP, and MusQBOX.NMI were independent factors associated with post-chemotherapy myelosuppression.</p><p><strong>Conclusions: </strong>QUS parameters show promise in characterizing muscle strength, mass, and quality. They are also independent factors influencing post-chemotherapy myelosuppression.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142647492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reliability of Semitendinosus and Biceps Femoris Aponeurosis Thickness Using B-Mode Ultrasound. 使用 B 型超声波测量半腱肌和股二头肌肌腱厚度的可靠性
IF 2.1 4区 医学 Q2 ACOUSTICS Pub Date : 2024-11-12 DOI: 10.1002/jum.16616
Chrysostomos Sahinis, Eleftherios Kellis

Objectives: The aim of the present study was to assess the reliability of aponeurosis and muscle thickness of the hamstrings using ultrasound (US).

Methods: US images were captured from the semitendinosus (ST) and biceps femoris long head (BFlh) of 30 individuals (15 females), undergoing two testing sessions with a 24-hour interval. Measurements were taken at six sites along the thigh at two knee angles (0° = full extension and 90°) in prone position. Aponeurosis and muscle thickness across the entire length of ST and BFlh were evaluated using computational image segmentation which generated ~360 data points per participant.

Results: The intraclass correlation coefficients ranged from 0.937 to 0.998 while the standard error of measurement varied from 0.88 to 2.72% for superficial aponeurosis, from 1.41 to 2.29% for deep aponeurosis, and from 1.50 to 4.22% for muscle thickness. The minimal detectable change ranged from 2.44 to 7.56% for the superficial aponeurosis, from 3.57 to 6.27% for deep aponeurosis, and from 4.17 to 11.70% for BF and ST muscle thickness.

Conclusions: Evaluation of hamstring aponeurosis and muscle thickness measurements at rest displayed very high reliability and, hence, such measurements can be used to diagnose changes in thickness due to injury or exercise interventions.

目的:本研究旨在利用超声波(US)评估腘绳肌的肌腱和肌肉厚度的可靠性:本研究旨在使用超声波(US)评估腘绳肌的肌腱和肌肉厚度的可靠性:方法:对 30 人(15 名女性)的半腱肌(ST)和股二头肌长头(BFlh)进行超声波图像采集。在俯卧姿势下,沿大腿在两个膝关节角度(0° = 完全伸直和 90°)的六个部位进行测量。采用计算图像分割法对 ST 和 BFlh 整个长度上的肌腱和肌肉厚度进行评估,每位参与者可获得约 360 个数据点:类内相关系数从 0.937 到 0.998 不等,而浅层肌腱的测量标准误差从 0.88 到 2.72% 不等,深层肌腱的测量标准误差从 1.41 到 2.29% 不等,肌肉厚度的测量标准误差从 1.50 到 4.22% 不等。可检测到的最小变化范围为:浅层肌腱从 2.44% 到 7.56%,深层肌腱从 3.57% 到 6.27%,BF 和 ST 肌肉厚度从 4.17% 到 11.70%:对静止状态下的腘绳肌腱和肌肉厚度测量结果的评估显示出极高的可靠性,因此,此类测量结果可用于诊断因损伤或运动干预导致的厚度变化。
{"title":"Reliability of Semitendinosus and Biceps Femoris Aponeurosis Thickness Using B-Mode Ultrasound.","authors":"Chrysostomos Sahinis, Eleftherios Kellis","doi":"10.1002/jum.16616","DOIUrl":"https://doi.org/10.1002/jum.16616","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of the present study was to assess the reliability of aponeurosis and muscle thickness of the hamstrings using ultrasound (US).</p><p><strong>Methods: </strong>US images were captured from the semitendinosus (ST) and biceps femoris long head (BFlh) of 30 individuals (15 females), undergoing two testing sessions with a 24-hour interval. Measurements were taken at six sites along the thigh at two knee angles (0° = full extension and 90°) in prone position. Aponeurosis and muscle thickness across the entire length of ST and BFlh were evaluated using computational image segmentation which generated ~360 data points per participant.</p><p><strong>Results: </strong>The intraclass correlation coefficients ranged from 0.937 to 0.998 while the standard error of measurement varied from 0.88 to 2.72% for superficial aponeurosis, from 1.41 to 2.29% for deep aponeurosis, and from 1.50 to 4.22% for muscle thickness. The minimal detectable change ranged from 2.44 to 7.56% for the superficial aponeurosis, from 3.57 to 6.27% for deep aponeurosis, and from 4.17 to 11.70% for BF and ST muscle thickness.</p><p><strong>Conclusions: </strong>Evaluation of hamstring aponeurosis and muscle thickness measurements at rest displayed very high reliability and, hence, such measurements can be used to diagnose changes in thickness due to injury or exercise interventions.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142622518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Methodology Used in Studies Aimed at Measuring Fetal Soft Tissues by 2D Ultrasound for the Screening of Large for Gestational Age Fetuses: A Systematic Review. 旨在通过二维超声测量胎儿软组织以筛查高龄胎儿的研究中使用的方法:系统回顾。
IF 2.1 4区 医学 Q2 ACOUSTICS Pub Date : 2024-11-11 DOI: 10.1002/jum.16614
Diego Lerma-Puertas, Ana Aguerri, Gema Pardina, Cristina Paules, David Lerma-Irureta, Daniel Oros, Sara Ruiz-Martínez

Management of suspected large for gestational age (LGA) fetuses remains unclear because ultrasound-estimated fetal weight (EFW) is not accurate. This was a systematic review of observational studies on fetal soft tissues measurements used alone or in combination to create a new EFW formula, to improve the screening for LGA fetuses. Studies were scored using a predefined set of independently agreed methodological criteria and an overall quality score was assigned for study design, statistical analysis, and reporting methods. There is a need to standardize methodologies for soft fetal tissue measurements. We propose a set of suggestions for this purpose.

由于超声估测的胎儿体重(EFW)并不准确,因此对疑似巨大胎儿(LGA)的处理仍不明确。本研究对有关胎儿软组织测量的观察性研究进行了系统性回顾,这些研究单独使用或结合使用了新的EFW公式,以改善LGA胎儿的筛查。研究采用预先确定的一套独立商定的方法学标准进行评分,并对研究设计、统计分析和报告方法进行总体质量评分。胎儿软组织测量方法需要标准化。为此,我们提出了一系列建议。
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引用次数: 0
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Journal of Ultrasound in Medicine
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