J. Ruiz, G. Ramirez, A. Munera, C. Arroyave, L. Castaño, P. López
The objetive of this study was to compare a single dose of secnidazole versus multiple doses of fenbendazole for the treatment of dogs with asymptomatic Giardia infection. Materials and methods: Twenty-four asymptomatic dogs with a positive test result for Giardia spp were randomized in two equal groups to receive a single dose of secnidazole at 30 mg/kg PO, or fenbendazole at 50 mg/ kg PO q24h for 3 days. Hematological parameters were evaluated before and 8 days after treatment, and feces were re-examined at days 8, 15, and 30 post-treatment by fecal flotation and antigen test. Results: The number of positive dogs in the fenbendazole group was: 1 (day 8) and 3 (days 15 and 30). In the secnidazole group, the number of positive cases were: 4 (day 8), 3 (day 15), and 1 (day 30). Conclusion: Treatment with secnidazole or fenbendazole, were effective between 75% and 92% to eliminate the excretion of Giardia cysts in canines together with hygienic measures to control, like disinfection with quaternary ammonium of patients and their environment. Further studies that include more animals and multiple fecal exams on consecutive days would be necessary to confirm its efficacy in dogs.
{"title":"Comparison of Secnidazole and Fenbendazole for the Treatment of Asymptomatic Giardia Infection in Dogs","authors":"J. Ruiz, G. Ramirez, A. Munera, C. Arroyave, L. Castaño, P. López","doi":"10.30564/vsr.v1i1.1067","DOIUrl":"https://doi.org/10.30564/vsr.v1i1.1067","url":null,"abstract":"The objetive of this study was to compare a single dose of secnidazole versus multiple doses of fenbendazole for the treatment of dogs with asymptomatic Giardia infection. Materials and methods: Twenty-four asymptomatic dogs with a positive test result for Giardia spp were randomized in two equal groups to receive a single dose of secnidazole at 30 mg/kg PO, or fenbendazole at 50 mg/ kg PO q24h for 3 days. Hematological parameters were evaluated before and 8 days after treatment, and feces were re-examined at days 8, 15, and 30 post-treatment by fecal flotation and antigen test. Results: The number of positive dogs in the fenbendazole group was: 1 (day 8) and 3 (days 15 and 30). In the secnidazole group, the number of positive cases were: 4 (day 8), 3 (day 15), and 1 (day 30). Conclusion: Treatment with secnidazole or fenbendazole, were effective between 75% and 92% to eliminate the excretion of Giardia cysts in canines together with hygienic measures to control, like disinfection with quaternary ammonium of patients and their environment. Further studies that include more animals and multiple fecal exams on consecutive days would be necessary to confirm its efficacy in dogs.","PeriodicalId":17588,"journal":{"name":"Journal of Veterinary Science and Research","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81695892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EFSA released the 89-page Scientific Opinion “Evaluation of the health risks related to the presence of cyanogenic glycosides in foods other than raw apricot kernels”. This opinion, and the ensuring media coverage, has left uncertainty in the minds of consumers, feed and supplement manufacturers and flaxseed producers of how much ground flaxseed can safely be consumed without crossing the threshold of cyanide toxicity. This editorial updates the science and tries to bring clarity to the question “how much flaxseed can I safely feed my dog, cat, horse on a daily basis?” and “how much can I safely eat?” The great majority of ground flaxseed products have a cyanogenic glycoside content of less than 200 mg / kg seed. For people, consuming 30 grams of such flaxseed the average peak blood cyanide concentration will be about 5 µmole / L, much less than the toxic threshold value of 20 to 40 µmole / L favoured by EFSA. Thus, as much as 120 grams of crushed / ground flaxseed can be consumed by a 70 kg adult person before a toxic threshold of 40 µmole / L is reached (up to 1.7 grams ground flaxseed / kg body weight). The toxic threshold of cyanide for dogs is 2 to 4-fold greater than for humans, and unknown for cats and horses. The daily serving amounts for dogs and cats are about 0.23 grams / kg body mass per day, which will result in blood cyanide well below the toxic threshold. The highest recommended daily serving amount for horses is 454 grams per day, or 0.8 to 2 grams per kg / body mass depending on mass of the horse. This amount for horses should not be exceeded.
{"title":"Ground Flaxseed – How Safe is it for Companion Animals and for Us?","authors":"M. Lindinger","doi":"10.30564/vsr.v1i1.1158","DOIUrl":"https://doi.org/10.30564/vsr.v1i1.1158","url":null,"abstract":"EFSA released the 89-page Scientific Opinion “Evaluation of the health risks related to the presence of cyanogenic glycosides in foods other than raw apricot kernels”. This opinion, and the ensuring media coverage, has left uncertainty in the minds of consumers, feed and supplement manufacturers and flaxseed producers of how much ground flaxseed can safely be consumed without crossing the threshold of cyanide toxicity. This editorial updates the science and tries to bring clarity to the question “how much flaxseed can I safely feed my dog, cat, horse on a daily basis?” and “how much can I safely eat?” The great majority of ground flaxseed products have a cyanogenic glycoside content of less than 200 mg / kg seed. For people, consuming 30 grams of such flaxseed the average peak blood cyanide concentration will be about 5 µmole / L, much less than the toxic threshold value of 20 to 40 µmole / L favoured by EFSA. Thus, as much as 120 grams of crushed / ground flaxseed can be consumed by a 70 kg adult person before a toxic threshold of 40 µmole / L is reached (up to 1.7 grams ground flaxseed / kg body weight). The toxic threshold of cyanide for dogs is 2 to 4-fold greater than for humans, and unknown for cats and horses. The daily serving amounts for dogs and cats are about 0.23 grams / kg body mass per day, which will result in blood cyanide well below the toxic threshold. The highest recommended daily serving amount for horses is 454 grams per day, or 0.8 to 2 grams per kg / body mass depending on mass of the horse. This amount for horses should not be exceeded.","PeriodicalId":17588,"journal":{"name":"Journal of Veterinary Science and Research","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74198671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Haverbeke, S. Uccheddu, Heidi Arnouts, A. Sannen
The influence of essential oils (EOs) on emotions has been widely described among humans and animals. Several studies have investigated the effects and the actions of EOs on behaviour, mood and perception. In this study, shelter dogs (n=23) were exposed to olfactory stimulation through diffusion of 9 anxiolytic essential oils in one blend (olfactory enrichment) for 8 weeks in order to check long-term effects on behaviour. First, dog’s postures have been evaluated in both groups before and after exposure. Secondly, in order to collect the preliminary results on the distance necessary to obtain an effect of EOs, dogs were divided in 2 groups according to the distance from the diffuser. Our results indicate that olfactory enrichment with this blend of EOs is related to less time spent by dogs in high posture. More research is needed to investigate a potential gradual effect of distance and concentration of EOs on dog’s welfare.
{"title":"A Pilot Study on Behavioural Responses of Shelter Dogs to Olfactory Enrichment","authors":"A. Haverbeke, S. Uccheddu, Heidi Arnouts, A. Sannen","doi":"10.30564/vsr.v1i1.1147","DOIUrl":"https://doi.org/10.30564/vsr.v1i1.1147","url":null,"abstract":"The influence of essential oils (EOs) on emotions has been widely described among humans and animals. Several studies have investigated the effects and the actions of EOs on behaviour, mood and perception. In this study, shelter dogs (n=23) were exposed to olfactory stimulation through diffusion of 9 anxiolytic essential oils in one blend (olfactory enrichment) for 8 weeks in order to check long-term effects on behaviour. First, dog’s postures have been evaluated in both groups before and after exposure. Secondly, in order to collect the preliminary results on the distance necessary to obtain an effect of EOs, dogs were divided in 2 groups according to the distance from the diffuser. Our results indicate that olfactory enrichment with this blend of EOs is related to less time spent by dogs in high posture. More research is needed to investigate a potential gradual effect of distance and concentration of EOs on dog’s welfare. ","PeriodicalId":17588,"journal":{"name":"Journal of Veterinary Science and Research","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86280023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-12DOI: 10.36811/jvsr.2019.110004
N. Kumari, Shubham Loat, Shallu Saini, Nitika Dhilor, Anurag Kumar, R. Kataria
The major histocompatibility complex (MHC) is an organized cluster of tightly linked genes, present in all vertebrates, playing an important role in the immune system, except the jawless fish [1]. MHC was first identified during tissue transplantation studies in mice [2] and was first known for its role in histocompatibility. Consequently, the role of MHC was discovered in immune regulation [3] and several other functions [4,5]. The important function of the MHC is to code for specialized antigen-presenting receptor glycoproteins, also called as MHC molecules. The products of these genes are involved in the induction and regulation of immune response. These molecules bind processed peptide antigens and present them to T-lymphocytes, thereby triggering immune response.
{"title":"Role of BoLA-DRB3 genetic diversity against resistance to mastitis in cattle: Review","authors":"N. Kumari, Shubham Loat, Shallu Saini, Nitika Dhilor, Anurag Kumar, R. Kataria","doi":"10.36811/jvsr.2019.110004","DOIUrl":"https://doi.org/10.36811/jvsr.2019.110004","url":null,"abstract":"The major histocompatibility complex (MHC) is an organized cluster of tightly linked genes, present in all vertebrates, playing an important role in the immune system, except the jawless fish [1]. MHC was first identified during tissue transplantation studies in mice [2] and was first known for its role in histocompatibility. Consequently, the role of MHC was discovered in immune regulation [3] and several other functions [4,5]. The important function of the MHC is to code for specialized antigen-presenting receptor glycoproteins, also called as MHC molecules. The products of these genes are involved in the induction and regulation of immune response. These molecules bind processed peptide antigens and present them to T-lymphocytes, thereby triggering immune response.","PeriodicalId":17588,"journal":{"name":"Journal of Veterinary Science and Research","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84696215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-08DOI: 10.36811/JVSR.2019.110003
F. A. Mansour, H. G. El-Hak, M. Ghobashy, Maha F. M. Soliman, N. S. El-Shenawy
The most significant pollutants are the heavy metals in the aquatic network due to their toxicity, accumulation, and bio-magnification. In an attempt to characterize the physical-chemical and demonstrate the potential water impact of the heavy metal content of wastes in two lakes in Sharkia province, Egypt, this study was developed to determine their toxicity and the potential waste impacts in biochemistry and histology of fish muscle. Samples of water and fish muscles were collected and analyzed for heavy metals using atomic absorption of two different fish species (Oreochromis niloticus and Clarias gariepinus) along two canals in Sharkia province in Egypt during the four seasons in 2018. The water samples were also analyzed for the physicochemical parameters. The impact of heavy metal on the enzymatic antioxidant (superoxide dismutase and catalase) as well as the reduced glutathione content, besides the oxidative stress marker presented by lipid peroxidation levels in fish muscles, were evaluated. Results showed the largest amount of chloride (Cl-) and iron (Fe) in the Sharkia water sample, while Faquas water sample had the highest level of HCO3 and iron (Fe). The manganese concentration in the fish muscle was the highest in Sharkia water and the highest level of Fe was detected in the fish muscles collected from Faquas area. These high levels of some of the physicochemical parameters and heavy metals in the two lakes with two different wastes as seen in this study may be a source of water pollution. The highest accumulation of metals in the muscle of the two fish species, suggesting risk for human consumption. There were seasonal variations in the level of LPO in muscle tissue of two types of fishes with a reverse relationship with antioxidant parameters. This accumulation varied seasonal and spatial as well as according to the species of fish. Increasing the level of heavy metals effect on the biochemistry and histology of fish. Keywords: Heavy metals; Muscle; Oxidative/Antioxidant, Histology, Clarias gariepinus; Oreochromis niloticus
{"title":"Assessment of seasonal and spatial variations of heavy metals in the muscles of Oreochromis niloticus and Clarias gariepinus at Sharkia province, Egypt: Biochemistry and Histology Evaluation","authors":"F. A. Mansour, H. G. El-Hak, M. Ghobashy, Maha F. M. Soliman, N. S. El-Shenawy","doi":"10.36811/JVSR.2019.110003","DOIUrl":"https://doi.org/10.36811/JVSR.2019.110003","url":null,"abstract":"The most significant pollutants are the heavy metals in the aquatic network due to their toxicity, accumulation, and bio-magnification. In an attempt to characterize the physical-chemical and demonstrate the potential water impact of the heavy metal content of wastes in two lakes in Sharkia province, Egypt, this study was developed to determine their toxicity and the potential waste impacts in biochemistry and histology of fish muscle. Samples of water and fish muscles were collected and analyzed for heavy metals using atomic absorption of two different fish species (Oreochromis niloticus and Clarias gariepinus) along two canals in Sharkia province in Egypt during the four seasons in 2018. The water samples were also analyzed for the physicochemical parameters. The impact of heavy metal on the enzymatic antioxidant (superoxide dismutase and catalase) as well as the reduced glutathione content, besides the oxidative stress marker presented by lipid peroxidation levels in fish muscles, were evaluated. Results showed the largest amount of chloride (Cl-) and iron (Fe) in the Sharkia water sample, while Faquas water sample had the highest level of HCO3 and iron (Fe). The manganese concentration in the fish muscle was the highest in Sharkia water and the highest level of Fe was detected in the fish muscles collected from Faquas area. These high levels of some of the physicochemical parameters and heavy metals in the two lakes with two different wastes as seen in this study may be a source of water pollution. The highest accumulation of metals in the muscle of the two fish species, suggesting risk for human consumption. There were seasonal variations in the level of LPO in muscle tissue of two types of fishes with a reverse relationship with antioxidant parameters. This accumulation varied seasonal and spatial as well as according to the species of fish. Increasing the level of heavy metals effect on the biochemistry and histology of fish.\u0000\u0000Keywords: Heavy metals; Muscle; Oxidative/Antioxidant, Histology, Clarias gariepinus; Oreochromis niloticus","PeriodicalId":17588,"journal":{"name":"Journal of Veterinary Science and Research","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89393385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-01DOI: 10.36811/jvsr.2019.110002
Miguel Vieira de Melo Netoc
Amazonian rainforest aquatic ecosystem is a very unique ecosystem in the Earth, which waters from the Amazon basin have distinct physicochemical and optical characteristics (black, clear and white). In this mini review paper, Amazon status of bioaccumulation and biomagnifications of Hg and MeHg is discussed. Emphasis has been given to understand the effect of BSAF on the aquatic trophic chain (plankton, macroinvertebrates). Keywords: Mercury; Methylmercury; Amazon
{"title":"Amazon types of waters, BSAF (Biota Sediment Accumulation Factor), biomagnification and bioaccumulation of Hg","authors":"Miguel Vieira de Melo Netoc","doi":"10.36811/jvsr.2019.110002","DOIUrl":"https://doi.org/10.36811/jvsr.2019.110002","url":null,"abstract":"Amazonian rainforest aquatic ecosystem is a very unique ecosystem in the Earth, which waters from the Amazon basin have distinct physicochemical and optical characteristics (black, clear and white). In this mini review paper, Amazon status of bioaccumulation and biomagnifications of Hg and MeHg is discussed. Emphasis has been given to understand the effect of BSAF on the aquatic trophic chain (plankton, macroinvertebrates).\u0000\u0000Keywords: Mercury; Methylmercury; Amazon","PeriodicalId":17588,"journal":{"name":"Journal of Veterinary Science and Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82354391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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