Pub Date : 2022-05-20DOI: 10.11150/kansenshogakuzasshi.96.101
Nanase Watatani, O. Nishiyama, Y. Kunita, A. Sano, H. Sano, Koichi Yoshida, Y. Tohda
{"title":"A Case of Asymptomatic Toxocariasis Encountered after Enforcement of a Ban on the Ingestion of the Raw Liver of Cows","authors":"Nanase Watatani, O. Nishiyama, Y. Kunita, A. Sano, H. Sano, Koichi Yoshida, Y. Tohda","doi":"10.11150/kansenshogakuzasshi.96.101","DOIUrl":"https://doi.org/10.11150/kansenshogakuzasshi.96.101","url":null,"abstract":"","PeriodicalId":17713,"journal":{"name":"Kansenshogaku Zasshi","volume":"96 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75949319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-20DOI: 10.11150/kansenshogakuzasshi.96.65
Yasuo Kurata, Noboru Inoue, Satoko Kondo, K. Onozawa, N. Tani, J. Minami, R. Oishi, S. Nagano, H. Araki, H. Kuwano
This study was aimed at monitoring the adverse reactions to tozinameran (mRNA vaccine against SARS-CoV-2) in the vaccine recipients, and to investigate factors that might affect the risk of development of these reactions. The adverse events (13 injection-site and systemic reactions) on day 1 (vaccination day), day 2, day 3, day 4, and day 5- were monitored in the employees of Fukuoka City Hospital who were vaccinated at the hospital between March 2021 and April 2021. The severities of the adverse reactions were also investigated. The frequencies of virtually all the adverse reactions were the highest on day 2, both after the first and after the second dose. The incidence of adverse reactions on day 2 after the first (and second) vaccine dose was 86.0% (86.9%) for pain at the injection site, 33.2% (76.9%) for fatigue, 14.3% (56.9%) for headache, 37.0% (57.2%) for myalgia, 5.2% (51.1%) for fever, and 9.3% (43.9%) for joint pain. The proportion of recipients with any adverse reactions on day 5- was significantly higher after the second dose than after the first dose. The incidence of moderate to severe adverse reactions (except for pain and swelling at the injection site, and rash) was also significantly higher after the second dose. Differences in the incidence of adverse reactions by sex, age, and number of doses were observed. In particular, female sex, age 55 years or under, and second vaccine dose were associated with a significantly increased incidence of fatigue and headache. Female sex and second vaccine dose were identified as being consistently associated with an increased frequency of adverse reactions. The results of the present study would be useful for predicting adverse reactions in prospective recipients, and for setting the vaccination day.
{"title":"Monitoring of Adverse Events Associated with COVID-19 Vaccine (Tozinameran) -Influence of Sex, Age, and Number of Doses on the Frequencies of Adverse Reactions-","authors":"Yasuo Kurata, Noboru Inoue, Satoko Kondo, K. Onozawa, N. Tani, J. Minami, R. Oishi, S. Nagano, H. Araki, H. Kuwano","doi":"10.11150/kansenshogakuzasshi.96.65","DOIUrl":"https://doi.org/10.11150/kansenshogakuzasshi.96.65","url":null,"abstract":"This study was aimed at monitoring the adverse reactions to tozinameran (mRNA vaccine against SARS-CoV-2) in the vaccine recipients, and to investigate factors that might affect the risk of development of these reactions. The adverse events (13 injection-site and systemic reactions) on day 1 (vaccination day), day 2, day 3, day 4, and day 5- were monitored in the employees of Fukuoka City Hospital who were vaccinated at the hospital between March 2021 and April 2021. The severities of the adverse reactions were also investigated. The frequencies of virtually all the adverse reactions were the highest on day 2, both after the first and after the second dose. The incidence of adverse reactions on day 2 after the first (and second) vaccine dose was 86.0% (86.9%) for pain at the injection site, 33.2% (76.9%) for fatigue, 14.3% (56.9%) for headache, 37.0% (57.2%) for myalgia, 5.2% (51.1%) for fever, and 9.3% (43.9%) for joint pain. The proportion of recipients with any adverse reactions on day 5- was significantly higher after the second dose than after the first dose. The incidence of moderate to severe adverse reactions (except for pain and swelling at the injection site, and rash) was also significantly higher after the second dose. Differences in the incidence of adverse reactions by sex, age, and number of doses were observed. In particular, female sex, age 55 years or under, and second vaccine dose were associated with a significantly increased incidence of fatigue and headache. Female sex and second vaccine dose were identified as being consistently associated with an increased frequency of adverse reactions. The results of the present study would be useful for predicting adverse reactions in prospective recipients, and for setting the vaccination day.","PeriodicalId":17713,"journal":{"name":"Kansenshogaku Zasshi","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87789701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-20DOI: 10.11150/kansenshogakuzasshi.96.112
Yuzo Tsuyuki, Yasuto Fukushima, Takashi Takahashi
{"title":"Characteristics of Bacteria Isolated in 2017-2020 from Japanese Companion Animals Using Blood Culture, Compared to Those Isolated in 2014-2016","authors":"Yuzo Tsuyuki, Yasuto Fukushima, Takashi Takahashi","doi":"10.11150/kansenshogakuzasshi.96.112","DOIUrl":"https://doi.org/10.11150/kansenshogakuzasshi.96.112","url":null,"abstract":"","PeriodicalId":17713,"journal":{"name":"Kansenshogaku Zasshi","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81158456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-20DOI: 10.11150/kansenshogakuzasshi.96.74
K. Ouchi, T. Yamazaki, C. Nakahama, S. Yamamoto, N. Tsumura, Y. Sakata, K. Nagai, S. Ikezawa, Toshihiro Tanaka, N. Nishimura, Tetsuya Yamaguchi, A. Nagita, S. Nishimura
{"title":"Evaluation of the Clinical Usefulness of Loop-mediated Isothermal Amplification (LAMP) Assay for the Detection of Chlamydia pneumoniae","authors":"K. Ouchi, T. Yamazaki, C. Nakahama, S. Yamamoto, N. Tsumura, Y. Sakata, K. Nagai, S. Ikezawa, Toshihiro Tanaka, N. Nishimura, Tetsuya Yamaguchi, A. Nagita, S. Nishimura","doi":"10.11150/kansenshogakuzasshi.96.74","DOIUrl":"https://doi.org/10.11150/kansenshogakuzasshi.96.74","url":null,"abstract":"","PeriodicalId":17713,"journal":{"name":"Kansenshogaku Zasshi","volume":"142 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84053361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-20DOI: 10.11150/kansenshogakuzasshi.96.91
Takayuki Yoshioka, Teruki Shin, Hitoshi Kooriyama, T. Ishii, Yoshisuke Haruna, H. Mataki
{"title":"A Case of Listeria monocytogenes Meningitis in a Man in the Prime of Life with a History of Frequent Consumption of Cheese and Dry-cured Ham","authors":"Takayuki Yoshioka, Teruki Shin, Hitoshi Kooriyama, T. Ishii, Yoshisuke Haruna, H. Mataki","doi":"10.11150/kansenshogakuzasshi.96.91","DOIUrl":"https://doi.org/10.11150/kansenshogakuzasshi.96.91","url":null,"abstract":"","PeriodicalId":17713,"journal":{"name":"Kansenshogaku Zasshi","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75451265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-20DOI: 10.11150/kansenshogakuzasshi.96.96
Masahito Oda, Mitsuya Katayama, N. Mori
{"title":"A Case of a Highly Drug-Resistant HIV Detected after Irregular Use of a Self-Prescribed Antiretroviral Drug","authors":"Masahito Oda, Mitsuya Katayama, N. Mori","doi":"10.11150/kansenshogakuzasshi.96.96","DOIUrl":"https://doi.org/10.11150/kansenshogakuzasshi.96.96","url":null,"abstract":"","PeriodicalId":17713,"journal":{"name":"Kansenshogaku Zasshi","volume":"273 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91458003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-20DOI: 10.11150/kansenshogakuzasshi.96.82
Yuka Ishihara, T. Yagi, Keigo Shibayama, M. Ohta
{"title":"Rate of Colonization and Serotypes of Streptococcus pneumoniae Isolated from Healthy Adult Community Residents after the Regulatory Approval of PPSV23","authors":"Yuka Ishihara, T. Yagi, Keigo Shibayama, M. Ohta","doi":"10.11150/kansenshogakuzasshi.96.82","DOIUrl":"https://doi.org/10.11150/kansenshogakuzasshi.96.82","url":null,"abstract":"","PeriodicalId":17713,"journal":{"name":"Kansenshogaku Zasshi","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73875778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-20DOI: 10.11150/kansenshogakuzasshi.96.39
Arisa Okamasa, Malek Okour, D. Austin, Y. Shida, J. Sager, Elizabeth L. Alexander, Dimitra Brintziki, A. Haggag, Stephen Harrison, Takako Hattori, Ian A. Hawes, Nobuhiko Okuda, Scott Segal, A. Skingsley, Robert X Williams, Esther S Yoon, Andrew M. Lippa
{"title":"Safety and Pharmacokinetics of the Anti-SARS-CoV-2 Monoclonal Antibody, Sotrovimab, Administered by Intravenous Injection in Japanese and Caucasian Healthy Volunteers","authors":"Arisa Okamasa, Malek Okour, D. Austin, Y. Shida, J. Sager, Elizabeth L. Alexander, Dimitra Brintziki, A. Haggag, Stephen Harrison, Takako Hattori, Ian A. Hawes, Nobuhiko Okuda, Scott Segal, A. Skingsley, Robert X Williams, Esther S Yoon, Andrew M. Lippa","doi":"10.11150/kansenshogakuzasshi.96.39","DOIUrl":"https://doi.org/10.11150/kansenshogakuzasshi.96.39","url":null,"abstract":"","PeriodicalId":17713,"journal":{"name":"Kansenshogaku Zasshi","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78230657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-20DOI: 10.11150/kansenshogakuzasshi.96.46
T. Yokoyama, Haruka Watanabe, Shou Iwasaka, T. Ishimaru
{"title":"A Study of Three Pregnant Women Who Gave Birth While Suffering from COVID-19","authors":"T. Yokoyama, Haruka Watanabe, Shou Iwasaka, T. Ishimaru","doi":"10.11150/kansenshogakuzasshi.96.46","DOIUrl":"https://doi.org/10.11150/kansenshogakuzasshi.96.46","url":null,"abstract":"","PeriodicalId":17713,"journal":{"name":"Kansenshogaku Zasshi","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82724025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-20DOI: 10.11150/kansenshogakuzasshi.96.52
Shintaro Nagashima, Yoshihiro Kitahara, Aya Sugiyama, Mafumi Okimoto, Bunthen E, Serge Ouoba, Ko Ko, T. Takafuta, J. Tanaka
This study was aimed at evaluating the changes in the antibody titers and neutralization ability before and after inoculation with an mRNA COVID-19 vaccine (Pfizer, USA) among healthcare professionals (HCPs) in Japan. A total of 221 HCPs were enrolled and their blood samples were collected at three time points: (1) before vaccination, (2) 3 weeks after the first dose, and (3) 3 weeks after the second dose. The titers of anti-SARS-CoV-2 Spike protein IgG antibody were measured in all the samples using VITROS-Anti-SARS-CoV-2 S1 Quant IgG Antibody (CLEIA, Ortho-Clinical Diagnostics, Inc.), and the surrogate Virus Neutralization Test (sVNT) (ELISA, GenScript, USA) was performed in the samples obtained after the vaccination. The anti-SARS-CoV-2 IgG titers were (1) median: 0.16;Interquartile (IQR): 0.10-0.27, (2) median: 250;IQR: 99.5-466 and (3) median: 2,400;IQR: 1,480-3,950, respectively, at the three time-points. Our study also revealed the relationship between the anti-SARS-CoV-2 IgG antibody titer and the antibody neutralization activity.
{"title":"Quantitative Measurement of the SARS-CoV-2 IgG Antibody and Surrogate Neutralizing Antibody Responses among mRNA COVID-19 Vaccine-Inoculated Medical Staff in Designated Medical Institutions for Infectious Diseases","authors":"Shintaro Nagashima, Yoshihiro Kitahara, Aya Sugiyama, Mafumi Okimoto, Bunthen E, Serge Ouoba, Ko Ko, T. Takafuta, J. Tanaka","doi":"10.11150/kansenshogakuzasshi.96.52","DOIUrl":"https://doi.org/10.11150/kansenshogakuzasshi.96.52","url":null,"abstract":"This study was aimed at evaluating the changes in the antibody titers and neutralization ability before and after inoculation with an mRNA COVID-19 vaccine (Pfizer, USA) among healthcare professionals (HCPs) in Japan. A total of 221 HCPs were enrolled and their blood samples were collected at three time points: (1) before vaccination, (2) 3 weeks after the first dose, and (3) 3 weeks after the second dose. The titers of anti-SARS-CoV-2 Spike protein IgG antibody were measured in all the samples using VITROS-Anti-SARS-CoV-2 S1 Quant IgG Antibody (CLEIA, Ortho-Clinical Diagnostics, Inc.), and the surrogate Virus Neutralization Test (sVNT) (ELISA, GenScript, USA) was performed in the samples obtained after the vaccination. The anti-SARS-CoV-2 IgG titers were (1) median: 0.16;Interquartile (IQR): 0.10-0.27, (2) median: 250;IQR: 99.5-466 and (3) median: 2,400;IQR: 1,480-3,950, respectively, at the three time-points. Our study also revealed the relationship between the anti-SARS-CoV-2 IgG antibody titer and the antibody neutralization activity.","PeriodicalId":17713,"journal":{"name":"Kansenshogaku Zasshi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72695561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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