Objective: Non-alcoholic fatty liver disease (NAFLD) is the most common cause of fatty liver without inflammatory infiltration, excessive alcohol consumption, viral hepatitis, and other liver diseases. NAFLD is a major health problem as it can lead to cirrhosis, liver cancer and mortality. In HIV-positive patients, the prevalence of NAFLD ranges from 28 to 48%. Currently, there is no information about the prevalence and related factors related to NAFLD in those with HIV infection in our country. In this study, we aimed to investigate the prevalence of NAFLD and the related factors in newly diagnosed HIV-infected patients. Methods: The demographic data and ultrasonography of 558 HIV-infected patients newly diagnosed between June 2015 and September 2019 were analyzed retrospectively. In hepatic echogenicity, fatty liver was diagnosed with hyper echogenicity of liver compared with renal cortex and diffusion. Uni- and multi-variate logistic regression analyses were applied to estimate factors associated with NAFLD. Results: Of 358 patients who met the study criteria, 118 (33%) were diagnosed as NAFLD. Obesity was found in 10.2% of the patients with NAFLD and in 3.1% of the patients without NAFLD (p=0.021). NAFLD rate was significantly higher in patients with diabetes mellitus and hypertension (p<0.05). In the multivariate analysis, age, 1 mg/dl increase in glucose and triglyceride values and 1 unit increase in ALT/AST were associated with NAFLD. Conclusions: The results highlight the importance of early recognition and management of NAFLD and traditional factors associated with NAFLD in Turkish patients with HIV infection. Additionally, precautions and treatments should be a priority in the follow-up of patients in order to ensure the reduction of liver-related morbidity and mortality, which is one of the non-AIDS causes of these newly diagnosed HIV-infected patients.
{"title":"Prevalence and Related Risk Factors of Non-Alcoholic Fatty Liver Disease In HIV/AIDS Patients","authors":"Figen Sarıgül, M. Deniz","doi":"10.36519/KD.2021.09","DOIUrl":"https://doi.org/10.36519/KD.2021.09","url":null,"abstract":"Objective: Non-alcoholic fatty liver disease (NAFLD) is the most common cause of fatty liver without inflammatory infiltration, excessive alcohol consumption, viral hepatitis, and other liver diseases. NAFLD is a major health problem as it can lead to cirrhosis, liver cancer and mortality. In HIV-positive patients, the prevalence of NAFLD ranges from 28 to 48%. Currently, there is no information about the prevalence and related factors related to NAFLD in those with HIV infection in our country. In this study, we aimed to investigate the prevalence of NAFLD and the related factors in newly diagnosed HIV-infected patients. Methods: The demographic data and ultrasonography of 558 HIV-infected patients newly diagnosed between June 2015 and September 2019 were analyzed retrospectively. In hepatic echogenicity, fatty liver was diagnosed with hyper echogenicity of liver compared with renal cortex and diffusion. Uni- and multi-variate logistic regression analyses were applied to estimate factors associated with NAFLD. Results: Of 358 patients who met the study criteria, 118 (33%) were diagnosed as NAFLD. Obesity was found in 10.2% of the patients with NAFLD and in 3.1% of the patients without NAFLD (p=0.021). NAFLD rate was significantly higher in patients with diabetes mellitus and hypertension (p<0.05). In the multivariate analysis, age, 1 mg/dl increase in glucose and triglyceride values and 1 unit increase in ALT/AST were associated with NAFLD. Conclusions: The results highlight the importance of early recognition and management of NAFLD and traditional factors associated with NAFLD in Turkish patients with HIV infection. Additionally, precautions and treatments should be a priority in the follow-up of patients in order to ensure the reduction of liver-related morbidity and mortality, which is one of the non-AIDS causes of these newly diagnosed HIV-infected patients.","PeriodicalId":17826,"journal":{"name":"Klimik Dergisi/Klimik Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82798708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Cetinkaya, Hatice Karagoz, Orhan Yıldız, Ic Hastaliklari Klinigi Kayseri Turkiye Acibadem Kayseri Hastanesi
Objective: Since the first case from Wuhan, China in December 2019, COVID-19 has spread all over the world and a pandemic was declared by the World Health Organization on January 30, 2020 While there are no specific effective antiviral drugs or vaccines to treat or to prevent COVID-19;favipiravir, hydroxychloroquine and their combination are used in the treatment of COVID-19 in Turkey In this study, it was aimed to evaluate the demographic, clinical and laboratory findings, the treatments given and the effects of treatments on liver tests of the patients followed up with the diagnosis of COVID-19
{"title":"Comparison of Liver Safety of Favipiravir and Hydroxychloroquine in COVID-19 Treatment","authors":"F. Cetinkaya, Hatice Karagoz, Orhan Yıldız, Ic Hastaliklari Klinigi Kayseri Turkiye Acibadem Kayseri Hastanesi","doi":"10.5152/kd.2020.49","DOIUrl":"https://doi.org/10.5152/kd.2020.49","url":null,"abstract":"Objective: Since the first case from Wuhan, China in December 2019, COVID-19 has spread all over the world and a pandemic was declared by the World Health Organization on January 30, 2020 While there are no specific effective antiviral drugs or vaccines to treat or to prevent COVID-19;favipiravir, hydroxychloroquine and their combination are used in the treatment of COVID-19 in Turkey In this study, it was aimed to evaluate the demographic, clinical and laboratory findings, the treatments given and the effects of treatments on liver tests of the patients followed up with the diagnosis of COVID-19","PeriodicalId":17826,"journal":{"name":"Klimik Dergisi/Klimik Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74152518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Tartar, Ş. Balın, A. Akbulut, M. Gonen, Kutbeddin Demirdağ, Tip Fakultesi Noroloji Anabilim Dali Elazig Turkiye Firat Universitesi
{"title":"A Case of Herpes Simplex Virus Encephalitis Without Pleocytosis in Cerebrospinal Fluid and Complicated With Intracranial Hematoma","authors":"A. Tartar, Ş. Balın, A. Akbulut, M. Gonen, Kutbeddin Demirdağ, Tip Fakultesi Noroloji Anabilim Dali Elazig Turkiye Firat Universitesi","doi":"10.5152/kd.2020.66","DOIUrl":"https://doi.org/10.5152/kd.2020.66","url":null,"abstract":"","PeriodicalId":17826,"journal":{"name":"Klimik Dergisi/Klimik Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73367020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erhan Alkan, Gastroenteroloji Klinigi Antalya Turkiye Antalya Yasam Hastanesi, M. Akın, Y. Tuna, Gastroenteroloji Klinigi Antalya Turkiye Medical Park Antalya Hastanesi
{"title":"Entecavir and Tenofovir Treatment in Patients With Hepatitis B Virus-Related Cirrhosis: A Comparison of Results of Two-Year Treatment","authors":"Erhan Alkan, Gastroenteroloji Klinigi Antalya Turkiye Antalya Yasam Hastanesi, M. Akın, Y. Tuna, Gastroenteroloji Klinigi Antalya Turkiye Medical Park Antalya Hastanesi","doi":"10.5152/kd.2020.54","DOIUrl":"https://doi.org/10.5152/kd.2020.54","url":null,"abstract":"","PeriodicalId":17826,"journal":{"name":"Klimik Dergisi/Klimik Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76007816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Time to Handover to the New Editor-in-Chief","authors":"H. Eraksoy","doi":"10.5152/kd.2020.44","DOIUrl":"https://doi.org/10.5152/kd.2020.44","url":null,"abstract":"","PeriodicalId":17826,"journal":{"name":"Klimik Dergisi/Klimik Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82422500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Coşkun, Anesteziyoloji ve Reanimasyon Klinigi Antalya Turkiye Kepez Devlet Hastanesi, Senay Ozturk Durmaz
{"title":"Evaluation of the Relationship Between Vitamin D Levels and Mortality and Morbidity in Intensive Care Unit Patients With Pneumonia","authors":"A. Coşkun, Anesteziyoloji ve Reanimasyon Klinigi Antalya Turkiye Kepez Devlet Hastanesi, Senay Ozturk Durmaz","doi":"10.5152/kd.2020.56","DOIUrl":"https://doi.org/10.5152/kd.2020.56","url":null,"abstract":"","PeriodicalId":17826,"journal":{"name":"Klimik Dergisi/Klimik Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75570810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. E. Gökler, Halk Sagligi Enstitusu Ankara Turkiye Ankara Yildirim Beyazit Universitesi, Hasan Durmuş, A. Atesoglu, Halk Sagligi Hizmetleri Baskanligi Hatay Turkiye Dortyol Ilce Saglik Mudurlugu
{"title":"Evaluation and Risk Mapping of Cutaneous Leishmaniasis Cases Between 2007 and 2017 in Sanliurfa, Turkey","authors":"M. E. Gökler, Halk Sagligi Enstitusu Ankara Turkiye Ankara Yildirim Beyazit Universitesi, Hasan Durmuş, A. Atesoglu, Halk Sagligi Hizmetleri Baskanligi Hatay Turkiye Dortyol Ilce Saglik Mudurlugu","doi":"10.5152/kd.2020.51","DOIUrl":"https://doi.org/10.5152/kd.2020.51","url":null,"abstract":"","PeriodicalId":17826,"journal":{"name":"Klimik Dergisi/Klimik Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89445265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Mirza, Tip Fakultesi Tibbi Mikrobiyoloji Anabilim Dali Ankara Baskent Universitesi, B. Sancak, Tip Fakultesi Tibbi Mikrobiyoloji Anabilim Dali Ankara Hacettepe Universitesi
{"title":"Comparison of Antimicrobial Susceptibilities of Escherichia coli Isolated From Urinary Cultures of Different Patient Groups: A University Hospital Experience","authors":"H. Mirza, Tip Fakultesi Tibbi Mikrobiyoloji Anabilim Dali Ankara Baskent Universitesi, B. Sancak, Tip Fakultesi Tibbi Mikrobiyoloji Anabilim Dali Ankara Hacettepe Universitesi","doi":"10.5152/kd.2020.55","DOIUrl":"https://doi.org/10.5152/kd.2020.55","url":null,"abstract":"","PeriodicalId":17826,"journal":{"name":"Klimik Dergisi/Klimik Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91529286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Streptococcus intermedius is part of the normal oropharyngeal, genitourinary and gastrointestinal flora, and can cause purulent infections characterized by abscess formation involving the brain and the liver tissue In this report, multiple pyogenic liver abscesses due to S intermedius in a 46-year-old male admitted to the emergency department with complaints of fever, cough, and weakness, and hospitalized with a diagnosis of suspected COVID-19 with pneumonia, is presented The diagnosis was made by isolating the agent from the abscess After percutaneous abscess drainage and antimicrobial treatment, the patient fully healed
{"title":"Multiple Pyogenic Liver Abscesses Due to Streptococcus intermedius","authors":"Merve Sarı, S. Cesur, Ç. Hatipoğlu, S. Kınıklı","doi":"10.5152/kd.2020.65","DOIUrl":"https://doi.org/10.5152/kd.2020.65","url":null,"abstract":"Streptococcus intermedius is part of the normal oropharyngeal, genitourinary and gastrointestinal flora, and can cause purulent infections characterized by abscess formation involving the brain and the liver tissue In this report, multiple pyogenic liver abscesses due to S intermedius in a 46-year-old male admitted to the emergency department with complaints of fever, cough, and weakness, and hospitalized with a diagnosis of suspected COVID-19 with pneumonia, is presented The diagnosis was made by isolating the agent from the abscess After percutaneous abscess drainage and antimicrobial treatment, the patient fully healed","PeriodicalId":17826,"journal":{"name":"Klimik Dergisi/Klimik Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89195544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}