Pub Date : 2019-09-28DOI: 10.1183/13993003.congress-2019.pa4729
H. Shafiek, S. Elbialy, Samar Elachy, A. Gad
Background and Objectives: Histopathology is a key element for the multidisciplinary diagnosis of diffuse parenchymal lung diseases (DPLD). We aimed to evaluate the efficacy, safety and diagnostic utility of bronchoscopic transbronchial cryobiopsy in diagnosing DPLD in Egyptian population and to identify the common DPLD pathologies in them. Methods: A prospective interventional study that enrolled 25 Egyptian patients presented to Main Alexandria University Hospital (Egypt) who had clinical and radiologic features of DPLD, but insufficient elements to achieve definite features of usual interstitial pneumonia (UIP/IPF) in chest high resolution computed tomography (HRCT). Twelve patients were subjected to transbronchial cryobiopsy and 13 patients to TBLB. Results: The diagnostic yield was significantly higher among transbronchial cryobiopsy group (83.3%) that increased to 100% with clinic-pathological correlation vs. TBLB group (38.5%,p= 0.041). Granulomatous diseases (24%; either sarcoidosis or hypersensitivity pneumonitis) were the common pathology followed by malignancy (12%) in both groups. The size of the TBLB was ranging from 1-3 mm vs. 2.5-5 mm in transbronchial cryobiopsy (p Conclusion: Transbronchial cryobiopsy is a safe tolerable procedure with high diagnostic yield for evaluating DPLD with indefinite UIP/IPF in HRCT.
{"title":"Transbronchial Cryobiopsy Validity in Diagnosing Indefinite Usual Interstitial Pneumonia in High Resolution Computed Tomography in Egyptian Population","authors":"H. Shafiek, S. Elbialy, Samar Elachy, A. Gad","doi":"10.1183/13993003.congress-2019.pa4729","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa4729","url":null,"abstract":"Background and Objectives: Histopathology is a key element for the multidisciplinary diagnosis of diffuse parenchymal lung diseases (DPLD). We aimed to evaluate the efficacy, safety and diagnostic utility of bronchoscopic transbronchial cryobiopsy in diagnosing DPLD in Egyptian population and to identify the common DPLD pathologies in them. Methods: A prospective interventional study that enrolled 25 Egyptian patients presented to Main Alexandria University Hospital (Egypt) who had clinical and radiologic features of DPLD, but insufficient elements to achieve definite features of usual interstitial pneumonia (UIP/IPF) in chest high resolution computed tomography (HRCT). Twelve patients were subjected to transbronchial cryobiopsy and 13 patients to TBLB. Results: The diagnostic yield was significantly higher among transbronchial cryobiopsy group (83.3%) that increased to 100% with clinic-pathological correlation vs. TBLB group (38.5%,p= 0.041). Granulomatous diseases (24%; either sarcoidosis or hypersensitivity pneumonitis) were the common pathology followed by malignancy (12%) in both groups. The size of the TBLB was ranging from 1-3 mm vs. 2.5-5 mm in transbronchial cryobiopsy (p Conclusion: Transbronchial cryobiopsy is a safe tolerable procedure with high diagnostic yield for evaluating DPLD with indefinite UIP/IPF in HRCT.","PeriodicalId":178396,"journal":{"name":"ILD/DPLD of known origin","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133448338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-28DOI: 10.1183/13993003.congress-2019.pa4738
A. Zahid, P. Chohan, T. Sheeran, A. Fahim
Introduction: Interstitial lung diseases (ILD), in the context of rheumatological disorders, present difficult diagnostic and management challenges.A combined rheumatology-ILD service has a potential to improve clinical outcomes in CTD-ILD. New Cross Hospital, a large district general hospital commenced providing this service in 2014 and we present an audit data over a 2 year period. Aims: To assess the effectiveness of combine rheumatology/ILD service at New Cross Hospital. Methods: A retrospective analysis of CTD-ILD clinic data over 2 years (January 2014- December 2015) was carried out. 78 patients, with known CTD, seen by both rheumatology and respiratory consultants in a combined clinical setting. All patients had proven pulmonary fibrosis on HRCT Chest. Results: Of the 78 patients, 10 patients (12%) had change in the diagnosis after clinic review. All patients (100%) had full lung functions after their first combined clinic review. Twenty five patients (32%) had a change in their management, (5 were treated with IV cyclophosphamide, 19 had an increase in prednisolone dosage while one patient received rituximab). No patient was felt to be a suitable candidate for lung transplantation. All patients had a transthoracic echocardiogram requested at their first clinic appointment to screen for pulmonary hypertension. Conclusions: Combined Rheumatology/ILD service reduces number of outpatient clinic appointments for patients with CTD-ILD. Moreover, it alters clinical management in a significant proportion of patients, improving diagnostic accuracy and clinical therapeutics.
{"title":"A Combined Rheumatology/ILD Service. The Wolverhampton Experience","authors":"A. Zahid, P. Chohan, T. Sheeran, A. Fahim","doi":"10.1183/13993003.congress-2019.pa4738","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa4738","url":null,"abstract":"Introduction: Interstitial lung diseases (ILD), in the context of rheumatological disorders, present difficult diagnostic and management challenges.A combined rheumatology-ILD service has a potential to improve clinical outcomes in CTD-ILD. New Cross Hospital, a large district general hospital commenced providing this service in 2014 and we present an audit data over a 2 year period. Aims: To assess the effectiveness of combine rheumatology/ILD service at New Cross Hospital. Methods: A retrospective analysis of CTD-ILD clinic data over 2 years (January 2014- December 2015) was carried out. 78 patients, with known CTD, seen by both rheumatology and respiratory consultants in a combined clinical setting. All patients had proven pulmonary fibrosis on HRCT Chest. Results: Of the 78 patients, 10 patients (12%) had change in the diagnosis after clinic review. All patients (100%) had full lung functions after their first combined clinic review. Twenty five patients (32%) had a change in their management, (5 were treated with IV cyclophosphamide, 19 had an increase in prednisolone dosage while one patient received rituximab). No patient was felt to be a suitable candidate for lung transplantation. All patients had a transthoracic echocardiogram requested at their first clinic appointment to screen for pulmonary hypertension. Conclusions: Combined Rheumatology/ILD service reduces number of outpatient clinic appointments for patients with CTD-ILD. Moreover, it alters clinical management in a significant proportion of patients, improving diagnostic accuracy and clinical therapeutics.","PeriodicalId":178396,"journal":{"name":"ILD/DPLD of known origin","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121825168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-28DOI: 10.1183/13993003.congress-2019.pa5184
N. Nathan, Clara Lauby, R. A. Taam, K. Bessaci, J. Brouard, M. Dalphin, C. Delacourt, C. Delestrain, A. Deschildre, J. Dubus, M. Fayon, L. Giovannini-Chami, V. Houdouin, A. Houzel, C. Marguet, I. Pin, P. Reix, M. Renoux, C. Schweitzer, A. Tatopoulos, C. Thumerelle, F. Troussier, S. Wanin, L. Weiss, A. Clément, P. Böelle, R. Epaud
Introduction: Health-related quality of life (HR-QoL) is an understudied area in rare diseases. Interstitial lung diseases in children (chILD) are heterogeneous disorders that are associated with a high morbidity and mortality. The impaired lung function, the nutritional impact and the burden of the treatments can impair the HR-QoL of these children. The aim of this study was to compare the HR-QoL in chILD to an aged-matched healthy population and to identify the factors that were associated to an altered QoL. Methods: Patients were recruited in the French RespiRare network. Patients with chILD of all causes, aged 1 month to 18 years were prospectively included. The children over 8 years old and the 2 parents of all children were asked to complete the PedsQLTM 4.0 Generic Core Scale (0 to 100 points). Results: A total of 78 children were included in the RespiRare centres. Total mean scores appeared to be significantly reduced in child self-report and in parent proxy-report (11.94 points (p=0.0003) and 14.08 points (p Conclusion: The study shows that HR-QoL is significantly impaired in chILD compared to a healthy population, using a validated generic QoL scale. Factors altering QoL score are easy to recognize and could help identify children at a heightened risk of low QoL. A longitudinal follow-up of HR-QoL in chILD is necessary to follow the impact of the disease and the treatments. To better appreciate chILD QoL, a specific scale is currently under study by the chILD-EU group.
{"title":"Health-related quality of life in children interstitial lung disease","authors":"N. Nathan, Clara Lauby, R. A. Taam, K. Bessaci, J. Brouard, M. Dalphin, C. Delacourt, C. Delestrain, A. Deschildre, J. Dubus, M. Fayon, L. Giovannini-Chami, V. Houdouin, A. Houzel, C. Marguet, I. Pin, P. Reix, M. Renoux, C. Schweitzer, A. Tatopoulos, C. Thumerelle, F. Troussier, S. Wanin, L. Weiss, A. Clément, P. Böelle, R. Epaud","doi":"10.1183/13993003.congress-2019.pa5184","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa5184","url":null,"abstract":"Introduction: Health-related quality of life (HR-QoL) is an understudied area in rare diseases. Interstitial lung diseases in children (chILD) are heterogeneous disorders that are associated with a high morbidity and mortality. The impaired lung function, the nutritional impact and the burden of the treatments can impair the HR-QoL of these children. The aim of this study was to compare the HR-QoL in chILD to an aged-matched healthy population and to identify the factors that were associated to an altered QoL. Methods: Patients were recruited in the French RespiRare network. Patients with chILD of all causes, aged 1 month to 18 years were prospectively included. The children over 8 years old and the 2 parents of all children were asked to complete the PedsQLTM 4.0 Generic Core Scale (0 to 100 points). Results: A total of 78 children were included in the RespiRare centres. Total mean scores appeared to be significantly reduced in child self-report and in parent proxy-report (11.94 points (p=0.0003) and 14.08 points (p Conclusion: The study shows that HR-QoL is significantly impaired in chILD compared to a healthy population, using a validated generic QoL scale. Factors altering QoL score are easy to recognize and could help identify children at a heightened risk of low QoL. A longitudinal follow-up of HR-QoL in chILD is necessary to follow the impact of the disease and the treatments. To better appreciate chILD QoL, a specific scale is currently under study by the chILD-EU group.","PeriodicalId":178396,"journal":{"name":"ILD/DPLD of known origin","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121421695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-28DOI: 10.1183/13993003.congress-2019.oa3598
A. Hoffmann-Vold, Y. Allanore, M. Alves, N. Graf, P. Airó, L. Ananyeva, L. Czirják, S. Guiducci, E. Hachulla, Mengtao Li, C. Mihai, G. Riemekasten, P. Sfikakis, G. Valentini, O. Kowal-Bielecka, O. Distler
{"title":"Disease course and outcome of progressive interstitial lung disease in systemic sclerosis","authors":"A. Hoffmann-Vold, Y. Allanore, M. Alves, N. Graf, P. Airó, L. Ananyeva, L. Czirják, S. Guiducci, E. Hachulla, Mengtao Li, C. Mihai, G. Riemekasten, P. Sfikakis, G. Valentini, O. Kowal-Bielecka, O. Distler","doi":"10.1183/13993003.congress-2019.oa3598","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.oa3598","url":null,"abstract":"","PeriodicalId":178396,"journal":{"name":"ILD/DPLD of known origin","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131805779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-28DOI: 10.1183/13993003.congress-2019.pa5190
P. Sojka, M. Sterclova, N. Kaspříková, M. Vašáková
Aim: To assess prognostic factors in patients with extrinsic allergic alveolitis (EAA). Material and methods: Into retrospective study 157 patients with EAA, 69 male (M); 88 female (F) were involved (mean age 57±15 years; 58±14 M; 57±16 F). At the time of diagnosis patients underwent assessment of history of exposure and sensitization to inhalations antigens (specific IgGs), bronchoalveolar lavage fluid (BALF) cellular analysis, lung function tests and high resolution computed tomography (HRCT) of the chest. Diagnosis of EAA was established by multidisciplinary team and treatment decision was made according to severity of symptoms, pulmonary functions and HRCT findings. Effect of demographic parameters, exposure and BALF lymphocytosis on outcome after 12 months observation period were investigated. Results: There was found positive correlation between CD4/CD8 ratio and treatment initiation (OR 5.6; 95% CI=1.55–22.5; p=0,003). Conclusion: The significant decline of lung functions showed patients with BALF LY
{"title":"Prognostic factors in patients with EAA","authors":"P. Sojka, M. Sterclova, N. Kaspříková, M. Vašáková","doi":"10.1183/13993003.congress-2019.pa5190","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa5190","url":null,"abstract":"Aim: To assess prognostic factors in patients with extrinsic allergic alveolitis (EAA). Material and methods: Into retrospective study 157 patients with EAA, 69 male (M); 88 female (F) were involved (mean age 57±15 years; 58±14 M; 57±16 F). At the time of diagnosis patients underwent assessment of history of exposure and sensitization to inhalations antigens (specific IgGs), bronchoalveolar lavage fluid (BALF) cellular analysis, lung function tests and high resolution computed tomography (HRCT) of the chest. Diagnosis of EAA was established by multidisciplinary team and treatment decision was made according to severity of symptoms, pulmonary functions and HRCT findings. Effect of demographic parameters, exposure and BALF lymphocytosis on outcome after 12 months observation period were investigated. Results: There was found positive correlation between CD4/CD8 ratio and treatment initiation (OR 5.6; 95% CI=1.55–22.5; p=0,003). Conclusion: The significant decline of lung functions showed patients with BALF LY","PeriodicalId":178396,"journal":{"name":"ILD/DPLD of known origin","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123704307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-28DOI: 10.1183/13993003.congress-2019.pa1374
M. Brovko, M. Kalashnikov, L. Akulkina, V. Sholomova, Alisa Yanakaewa, D. Konovalov, M. Lebedeva, T. Rosina, S. Moiseev
{"title":"Lung involvement in autoimmune liver diseases","authors":"M. Brovko, M. Kalashnikov, L. Akulkina, V. Sholomova, Alisa Yanakaewa, D. Konovalov, M. Lebedeva, T. Rosina, S. Moiseev","doi":"10.1183/13993003.congress-2019.pa1374","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa1374","url":null,"abstract":"","PeriodicalId":178396,"journal":{"name":"ILD/DPLD of known origin","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115387729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-28DOI: 10.1183/13993003.congress-2019.pa1368
Paloma Millán Billi, I. Castellví, Silvia Barril Farre, H. Park, Laura Martinez Martinez, L. Vilaro, Tomás Fraquet Casas, Francisco Aparicio, O. S. Vidal, H. Corominas, D. C. Villegas
{"title":"Diagnosing Sjogrën’ syndrome in patients with Interstitial Lung Disease by minor salivary gland biopsy","authors":"Paloma Millán Billi, I. Castellví, Silvia Barril Farre, H. Park, Laura Martinez Martinez, L. Vilaro, Tomás Fraquet Casas, Francisco Aparicio, O. S. Vidal, H. Corominas, D. C. Villegas","doi":"10.1183/13993003.congress-2019.pa1368","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa1368","url":null,"abstract":"","PeriodicalId":178396,"journal":{"name":"ILD/DPLD of known origin","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125427714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-28DOI: 10.1183/13993003.congress-2019.pa4726
N. Le-Dong, T. Hua-Huy, M. Topalovic, A. Dinh-Xuan
Objective: We introduce a new interpretation method for PFT data. Methods: Our new method consists of 3 steps: To build a diagnostic rule for a specific target from multi-PFT parameters. To estimate the Shapley-score, a game-theory based metric which measures the importance of each PFT index by comparing the model’s predictions with and without that index. To generate the interpretation, indicating the contribution level of each parameter to the positive/negative diagnosis. We applied this method to detect interstitial lung disease (ILD) in patients with systemic sclerosis. A machine learning diagnostic rule was developed from data of 300 patients undergoing 5 PFT techniques. Results: Validated on unseen data (n=100), the rule showed a good clinical performance (Sensitivity=0.86, Specificity=0.89, Positive and negative Likelihood-ratios of 7.86 and 0.16 respectively). At population level, the interpretation revealed that AV, TLCO-NO and FEV1 were the most important contributors to positive diagnosis. Personalized interpretations (Fig. 1) allow to verify the model’s plausibility in difficult cases with false negative/positive diagnosis and identify individual patterns of lung function impairments. Conclusion: Compared to the conventional approaches, our new method offers more advantages including ability of multivariate interpretation and valuable information for personalized treatment plan.
{"title":"Introduction of a new approach to interpret pulmonary function tests (PFT) based on Machine learning and Game theory","authors":"N. Le-Dong, T. Hua-Huy, M. Topalovic, A. Dinh-Xuan","doi":"10.1183/13993003.congress-2019.pa4726","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa4726","url":null,"abstract":"Objective: We introduce a new interpretation method for PFT data. Methods: Our new method consists of 3 steps:\u0000 To build a diagnostic rule for a specific target from multi-PFT parameters. To estimate the Shapley-score, a game-theory based metric which measures the importance of each PFT index by comparing the model’s predictions with and without that index. To generate the interpretation, indicating the contribution level of each parameter to the positive/negative diagnosis. We applied this method to detect interstitial lung disease (ILD) in patients with systemic sclerosis. A machine learning diagnostic rule was developed from data of 300 patients undergoing 5 PFT techniques. Results: Validated on unseen data (n=100), the rule showed a good clinical performance (Sensitivity=0.86, Specificity=0.89, Positive and negative Likelihood-ratios of 7.86 and 0.16 respectively). At population level, the interpretation revealed that AV, TLCO-NO and FEV1 were the most important contributors to positive diagnosis. Personalized interpretations (Fig. 1) allow to verify the model’s plausibility in difficult cases with false negative/positive diagnosis and identify individual patterns of lung function impairments. Conclusion: Compared to the conventional approaches, our new method offers more advantages including ability of multivariate interpretation and valuable information for personalized treatment plan.","PeriodicalId":178396,"journal":{"name":"ILD/DPLD of known origin","volume":"180 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121311815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-28DOI: 10.1183/13993003.congress-2019.pa1364
O. Danilevskaya, A. Averyanov, V. Lesnyak
{"title":"Correlations of endomicroscopic and high-resolution computer tomography patterns in patients with interstitial lung diseases","authors":"O. Danilevskaya, A. Averyanov, V. Lesnyak","doi":"10.1183/13993003.congress-2019.pa1364","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa1364","url":null,"abstract":"","PeriodicalId":178396,"journal":{"name":"ILD/DPLD of known origin","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121668055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-28DOI: 10.1183/13993003.congress-2019.pa1369
P. Jacquerie, B. André, M. Henquet, C. Moermans, D. Seny, F. Gester, R. Louis, M. Malaise, J. Guiot
{"title":"Induced sputum in systemic sclerosis: A new potential for biomarkers in SSc","authors":"P. Jacquerie, B. André, M. Henquet, C. Moermans, D. Seny, F. Gester, R. Louis, M. Malaise, J. Guiot","doi":"10.1183/13993003.congress-2019.pa1369","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa1369","url":null,"abstract":"","PeriodicalId":178396,"journal":{"name":"ILD/DPLD of known origin","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127223373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：