Pub Date : 2023-09-21DOI: 10.33878/2073-7556-2023-22-3-94-103
M. Sukhina, M. H. Stavtsev, S. Achkasov, S. Yudin
AIM: to study the intestinal microbiota and identify its characteristic features in patients with colorectal cancer.PATIENTS AND METHODS: in this study, the composition of the intestinal microbiota in patients with colorectal cancer was analyzed, while the comparison group consisted of patients with non-inflammatory bowel diseases.RESULTS: previous studies have shown the possible role of enterococci and some types of clostridia in stimulating oncogenic processes and, on the contrary, the vital role of lactobacilli and bifidobacteria in intestinal homeostasis maintaining. The aim of this study was to compare the gut microbiota composition in colorectal cancer patients and non-inflammatory bowel diseases patients gut microbita. The proportion of enterococci was increased in patients with colorectal cancer (12.7% in the study group and 7.6% in the control group) on the contrary the proportion of bifidobacteria and obligate anaerobes was decreased (1.5% in the study group and 4% in the control groups) and (3.3 % of the study group and 9.7% in the control group) respectively. Decrease of the microbiota biodiversity was observed for the patients with colorectal cancer that was calculated by the Shannon diversity Index (4.46 in the study group and 4.8 in the control group), also two-fold increase of Pseudomonas aeruginosa share (2.2% in the study group and 1.1% in the control group) was found for this cohort, Clostridium septicum was isolated only from patients with colorectal cancer.CONCLUSION: this study results suggest the diagnostic significance of the species diversity of the intestinal microbiota.
{"title":"Characteristics of the intestinal microbiota in patients with colorectal cancer","authors":"M. Sukhina, M. H. Stavtsev, S. Achkasov, S. Yudin","doi":"10.33878/2073-7556-2023-22-3-94-103","DOIUrl":"https://doi.org/10.33878/2073-7556-2023-22-3-94-103","url":null,"abstract":"AIM: to study the intestinal microbiota and identify its characteristic features in patients with colorectal cancer.PATIENTS AND METHODS: in this study, the composition of the intestinal microbiota in patients with colorectal cancer was analyzed, while the comparison group consisted of patients with non-inflammatory bowel diseases.RESULTS: previous studies have shown the possible role of enterococci and some types of clostridia in stimulating oncogenic processes and, on the contrary, the vital role of lactobacilli and bifidobacteria in intestinal homeostasis maintaining. The aim of this study was to compare the gut microbiota composition in colorectal cancer patients and non-inflammatory bowel diseases patients gut microbita. The proportion of enterococci was increased in patients with colorectal cancer (12.7% in the study group and 7.6% in the control group) on the contrary the proportion of bifidobacteria and obligate anaerobes was decreased (1.5% in the study group and 4% in the control groups) and (3.3 % of the study group and 9.7% in the control group) respectively. Decrease of the microbiota biodiversity was observed for the patients with colorectal cancer that was calculated by the Shannon diversity Index (4.46 in the study group and 4.8 in the control group), also two-fold increase of Pseudomonas aeruginosa share (2.2% in the study group and 1.1% in the control group) was found for this cohort, Clostridium septicum was isolated only from patients with colorectal cancer.CONCLUSION: this study results suggest the diagnostic significance of the species diversity of the intestinal microbiota.","PeriodicalId":17840,"journal":{"name":"Koloproktologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89198809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-21DOI: 10.33878/2073-7556-2023-22-3-10-49
Y. Shelygin, V. Ivashkin, S. Achkasov, I. Reshetov, I. Maev, E. Belousova, Armen V. Vardanyan, B. Nanaeva, L. Adamyan, O. Drapkina, L. Namazova-Baranova, A. Razumovsky, A. Revishvili, I. Khatkov, A. Shabunin, M. Livzan, A. Sazhin, V. M. Timerbulatov, O. Khlynova, D. Abdulganieva, R. Abdulkhakov, Timofey L. Aleksandrov, O. P. Alekseeva, S. Alekseenko, I. S. Anosov, I. Bakulin, O. Barysheva, K. Bolikhov, V. Veselov, O. Golovenko, I. Gubonina, Anastasia I. Dolgushina, T. Zhigalova, A. Kagramanova, V. Kashnikov, O. Knyazev, Nikolay V. Kostenko, A. Likutov, E. Lomakina, I. D. Loranskaya, Airat F. Mingazov, A. I. Moskalev, I. Nazarov, N. V. Nikitina, Alfia H. Odintsova, V. Omelyanovsky, M. Osipenko, Аndrey V. Оshchepkov, V. Pavlenko, E. Poluektova, G. Rodoman, Anastasia M. Segal, S. Sitkin, M. Skalinskaya, A. Surkov, O. Sushkov, L. Tarasova, Yulia B. Uspenskaya, S. Frolov, E. Chashkova, O. Shifrin, O. Shcherbakova, O. Shchukina, T. V. Shkurko, P. Makarchuk
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{"title":"Clinical guidelines. Crohn’s disease (К50), adults","authors":"Y. Shelygin, V. Ivashkin, S. Achkasov, I. Reshetov, I. Maev, E. Belousova, Armen V. Vardanyan, B. Nanaeva, L. Adamyan, O. Drapkina, L. Namazova-Baranova, A. Razumovsky, A. Revishvili, I. Khatkov, A. Shabunin, M. Livzan, A. Sazhin, V. M. Timerbulatov, O. Khlynova, D. Abdulganieva, R. Abdulkhakov, Timofey L. Aleksandrov, O. P. Alekseeva, S. Alekseenko, I. S. Anosov, I. Bakulin, O. Barysheva, K. Bolikhov, V. Veselov, O. Golovenko, I. Gubonina, Anastasia I. Dolgushina, T. Zhigalova, A. Kagramanova, V. Kashnikov, O. Knyazev, Nikolay V. Kostenko, A. Likutov, E. Lomakina, I. D. Loranskaya, Airat F. Mingazov, A. I. Moskalev, I. Nazarov, N. V. Nikitina, Alfia H. Odintsova, V. Omelyanovsky, M. Osipenko, Аndrey V. Оshchepkov, V. Pavlenko, E. Poluektova, G. Rodoman, Anastasia M. Segal, S. Sitkin, M. Skalinskaya, A. Surkov, O. Sushkov, L. Tarasova, Yulia B. Uspenskaya, S. Frolov, E. Chashkova, O. Shifrin, O. Shcherbakova, O. Shchukina, T. V. Shkurko, P. Makarchuk","doi":"10.33878/2073-7556-2023-22-3-10-49","DOIUrl":"https://doi.org/10.33878/2073-7556-2023-22-3-10-49","url":null,"abstract":"<jats:p>.</jats:p>","PeriodicalId":17840,"journal":{"name":"Koloproktologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73699769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-21DOI: 10.33878/2073-7556-2023-22-3-129-133
Artem V. Volkov, V. V. Polovinkin
Methemoglobinemia were recorded in two patients with intestinal paresis and gastrostasis in the early postoperative period and unauthorized intake of Almagel by patients for the relief of heartburn.In the presented cases, drugs that can cause methemoglobinemia were used in the treatment: ropivacaine, metoclopramide, ketoprofen. Nevertheless, taking into account the pairing of the presented cases, it is impossible to exclude the effect of the drug Almagel on methemoglobin genesis.CONCLUSION: the presented cases demonstrate manifestations of rare and poorly recognized drug methemoglobinemia, probably as a result of taking the antacid drug Almagel. Timely diagnosis and treatment of this condition ensures the rapid reversibility of a complex multifactorial biochemical process.
{"title":"Methemoglobinemia in the postoperative period against the background of taking Almagel (clinical case)","authors":"Artem V. Volkov, V. V. Polovinkin","doi":"10.33878/2073-7556-2023-22-3-129-133","DOIUrl":"https://doi.org/10.33878/2073-7556-2023-22-3-129-133","url":null,"abstract":"Methemoglobinemia were recorded in two patients with intestinal paresis and gastrostasis in the early postoperative period and unauthorized intake of Almagel by patients for the relief of heartburn.In the presented cases, drugs that can cause methemoglobinemia were used in the treatment: ropivacaine, metoclopramide, ketoprofen. Nevertheless, taking into account the pairing of the presented cases, it is impossible to exclude the effect of the drug Almagel on methemoglobin genesis.CONCLUSION: the presented cases demonstrate manifestations of rare and poorly recognized drug methemoglobinemia, probably as a result of taking the antacid drug Almagel. Timely diagnosis and treatment of this condition ensures the rapid reversibility of a complex multifactorial biochemical process.","PeriodicalId":17840,"journal":{"name":"Koloproktologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90708258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-21DOI: 10.33878/2073-7556-2023-22-3-158-175
R. Novikov, S. Novikov
Analysis of the literature indicates the absence of domestic publications on the role of brachytherapy in patients with rectal cancer (RC). The aim of the presented work was to fill this gap and systematize the available information on various aspects of the clinical application of the two main variants for RC brachytherapy.
{"title":"Brachytherapy of rectal cancer: comparative characteristics of techniques (review)","authors":"R. Novikov, S. Novikov","doi":"10.33878/2073-7556-2023-22-3-158-175","DOIUrl":"https://doi.org/10.33878/2073-7556-2023-22-3-158-175","url":null,"abstract":"Analysis of the literature indicates the absence of domestic publications on the role of brachytherapy in patients with rectal cancer (RC). The aim of the presented work was to fill this gap and systematize the available information on various aspects of the clinical application of the two main variants for RC brachytherapy.","PeriodicalId":17840,"journal":{"name":"Koloproktologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82653987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-21DOI: 10.33878/2073-7556-2023-22-3-140-148
Amir A. Valiev, R. Hasanov, L. L. Galimova, I. Gataullin
AIM: to highlight modern methods of assessing the viability of the intestinal wall.MATERIALS AND METHODS: the search was made using electronic databases. We explored multiple sources, including, but not limited to, monographs, journal articles, books and websites.RESULTS: despite recent advances in scientific methods and technologies, currently the visual method remains the most popular for assessing the viability of the intestinal wall, which includes parameters such as color of the intestinal wall, peristalsis, and arterial pulsation.CONCLUSION: it would be fair to conclude that such methods as hyperspectral imaging, multimodal coherent tomography provide greater flexibility and details on the intestinal viability. However, further research is needed to determine their value in clinical practice. To the date, the most studied and applied method is fluorescent angiography, which allows to assess the viability of the intestine for most of its length.
{"title":"Modern methods of assessing the viability of the intestinal wall (review)","authors":"Amir A. Valiev, R. Hasanov, L. L. Galimova, I. Gataullin","doi":"10.33878/2073-7556-2023-22-3-140-148","DOIUrl":"https://doi.org/10.33878/2073-7556-2023-22-3-140-148","url":null,"abstract":"AIM: to highlight modern methods of assessing the viability of the intestinal wall.MATERIALS AND METHODS: the search was made using electronic databases. We explored multiple sources, including, but not limited to, monographs, journal articles, books and websites.RESULTS: despite recent advances in scientific methods and technologies, currently the visual method remains the most popular for assessing the viability of the intestinal wall, which includes parameters such as color of the intestinal wall, peristalsis, and arterial pulsation.CONCLUSION: it would be fair to conclude that such methods as hyperspectral imaging, multimodal coherent tomography provide greater flexibility and details on the intestinal viability. However, further research is needed to determine their value in clinical practice. To the date, the most studied and applied method is fluorescent angiography, which allows to assess the viability of the intestine for most of its length.","PeriodicalId":17840,"journal":{"name":"Koloproktologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85685137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-24DOI: 10.33878/2073-7556-2023-22-3-75
A. Editorial
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{"title":"COMMENT Eduard V. Denisenko, Valery L. Denisenko, Yury M. Gain, Konstantin G. Tsyplakov, Gennady D. Korobov Comparative analysis of the effectiveness of the treatment of transsphincter anal fistulas by various methods","authors":"A. Editorial","doi":"10.33878/2073-7556-2023-22-3-75","DOIUrl":"https://doi.org/10.33878/2073-7556-2023-22-3-75","url":null,"abstract":"<jats:p>.</jats:p>","PeriodicalId":17840,"journal":{"name":"Koloproktologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79516165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-24DOI: 10.33878/2073-7556-2023-22-3-128
A. Editorial
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{"title":"COMMENT Mariya Ya. Belikovа, Timofey L. Gorshenin, Irina K. Borovik, Yuriy A. Sizov Crohn's disease penetrating form. Difficulties of diagnostics and preoperative planning (clinical case)","authors":"A. Editorial","doi":"10.33878/2073-7556-2023-22-3-128","DOIUrl":"https://doi.org/10.33878/2073-7556-2023-22-3-128","url":null,"abstract":"<jats:p>.</jats:p>","PeriodicalId":17840,"journal":{"name":"Koloproktologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79222959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-24DOI: 10.33878/2073-7556-2023-22-3-110-111
A. Editorial
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{"title":"COMMENT Linara R. Khabibullina, Alexander Yu. Razumovsky, Olga V. Shсherbakova Surgical treatment of familial adenomatous polyposis in children: crosssectional study","authors":"A. Editorial","doi":"10.33878/2073-7556-2023-22-3-110-111","DOIUrl":"https://doi.org/10.33878/2073-7556-2023-22-3-110-111","url":null,"abstract":"<jats:p>.</jats:p>","PeriodicalId":17840,"journal":{"name":"Koloproktologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79606226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-21DOI: 10.33878/2073-7556-2023-22-2-141-148
N. Kopteev, T. S. Ovchinnikov, A. V. Lodygin, A. A. Bogatikov, V. A. Kashchenko
Every year there is an increase in the number of patients with intestinal stoma, which leads to an increase in the incidence of parastomal hernias (PSH). More than 50% of ostomy patients develop a parastomal hernia two or more years after radical surgery. To date, there are many surgical options for PSH, however, a unified algorithm for choosing an operational technique has not been evolved.The purpose of this review is to study modern surgical methods for the treatment of PSH and their late results, to determine the optimal approach and benefits.The review of the literature showed that in all cases of surgical treatment of PSH it is necessary to use mesh implants. The optimal technique for PSH hernioplasty is the laparoscopic version of Sugarbaker due to the low risk of recurrence and technical simplicity. In patients with large and giant PSH or hernia recurrence, STORRM is the technique of choice; classical stoma transposition is not used due to the high risk of recurrence. The use of Pauli/ePauli technique demonstrates a low recurrence rate, but there are no late results in this category of patients.
{"title":"Parastomal hernias: the current state (review)","authors":"N. Kopteev, T. S. Ovchinnikov, A. V. Lodygin, A. A. Bogatikov, V. A. Kashchenko","doi":"10.33878/2073-7556-2023-22-2-141-148","DOIUrl":"https://doi.org/10.33878/2073-7556-2023-22-2-141-148","url":null,"abstract":"Every year there is an increase in the number of patients with intestinal stoma, which leads to an increase in the incidence of parastomal hernias (PSH). More than 50% of ostomy patients develop a parastomal hernia two or more years after radical surgery. To date, there are many surgical options for PSH, however, a unified algorithm for choosing an operational technique has not been evolved.The purpose of this review is to study modern surgical methods for the treatment of PSH and their late results, to determine the optimal approach and benefits.The review of the literature showed that in all cases of surgical treatment of PSH it is necessary to use mesh implants. The optimal technique for PSH hernioplasty is the laparoscopic version of Sugarbaker due to the low risk of recurrence and technical simplicity. In patients with large and giant PSH or hernia recurrence, STORRM is the technique of choice; classical stoma transposition is not used due to the high risk of recurrence. The use of Pauli/ePauli technique demonstrates a low recurrence rate, but there are no late results in this category of patients.","PeriodicalId":17840,"journal":{"name":"Koloproktologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80162428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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