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The battle trauma of the esophagus 对抗食道创伤
Pub Date : 2022-12-23 DOI: 10.26779/2522-1396.2022.7-8.03
O. Usenko, A. Sydiuk, O. E. Sydiuk, A. Klimas, G. Savenko, O. Teslia
Objective. Estimation of efficacy of diagnosis and methods of treatment in patients, suffering the battle trauma of the esophagus. Materials and methods. In the Division of Thoraco–Abdominal Surgery of the Shalimov National Institute of Surgery and Transplantology the treatment of 7 patients with penetrating esophageal wounds was conducted. In 6 (85.7%) patients the penetrating gun–shot woundings were diagnosed, and in 1 (14.3%) patient – the closed thoracic trauma. Shrapnel woundings prevailed over the bullet woundings, occurring in5 (71.4%) and 2 (28.6%) patients, accordingly. Esophageal trauma as isolated affection, caused by the gun–shot penetraiting wounding was extremely rare – in 1 (14.3%) patient. Efficacy of diagnosis and surgical stationary treatment of esophageal trauma, caused by foreign bodies, was estimated, as well as the terms of the esophagus integrity restoration. Results. In 2 (2.6%) patients with pleural empyema open toracotomy access with further pleurectomy, pulmonary decortication, and restoration of the esophageal wall integrity was applied. In 4 (57.2%) patients thoracoscopy, pleurectomy, pulmonary decortication, and esophageal suturing were conducted. Intraoperatively in 6 (85.7%) patients the endoscopic vacuum therapy system was installed locally in the damaged esophagus portion. In 1 (14.3%) patient with local pleural empyema the treatment tactics consisted of the pleural cavity drainage under ultrasonographic control plus endoscopic vacuum therapy. For achievement of its optimal efficacy the pressure value was supported in range from 100 to 120 mm Hg. Endoscopic vacuum system was changed every 4 – 5 days. Average duration of the fistulas healing have constituted 1mo.
目标。评估食道创伤患者的诊断和治疗效果。材料和方法。沙利莫夫国立外科移植研究所胸腹外科对7例食管穿透性伤口进行了治疗。6例(85.7%)为穿透性枪伤,1例(14.3%)为闭合性胸外伤。弹片伤多于子弹伤,分别有5例(71.4%)和2例(28.6%)。食管外伤作为孤立性创伤,由枪弹穿透性损伤引起极为罕见,仅有1例(14.3%)。评估异物引起的食道创伤的诊断和手术固定治疗的疗效,以及食道完整性恢复的情况。结果。在2例(2.6%)胸膜脓胸患者中,采用开放式胸腔切开术,进一步胸膜切除,肺去皮,恢复食管壁完整性。4例(57.2%)患者行胸腔镜、胸膜切除术、肺去皮术、食管缝合术。术中6例(85.7%)患者将内镜下真空治疗系统局部安装在食管受损部位。1例(14.3%)局部胸膜脓肿采用超声控制下胸腔引流加内镜下真空治疗。为了达到最佳效果,压力值支持在100 - 120毫米汞柱范围内。内镜真空系统每4 - 5天更换一次。瘘管平均愈合时间为1个月。
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引用次数: 0
Esophageal and stomach varices: physiological and anatomical features of formation 食管和胃静脉曲张:形成的生理解剖特征
Pub Date : 2022-12-23 DOI: 10.26779/2522-1396.2022.7-8.41
S. Chooklin, S. Chuklin
Esophageal and stomach varices: physiological and anatomical features of formation
食管和胃静脉曲张:形成的生理解剖特征
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引用次数: 0
Morphological characteristics of the duodenal papilla magna tumors 十二指肠大乳头瘤的形态学特征
Pub Date : 2022-12-23 DOI: 10.26779/2522-1396.2022.7-8.14
O. Usenko, V. Kropelnytskyi, V. Shkarban, K. Tumasova, O. Pidopryhora
Objective. Studying of morphological characteristics of the duodenal papilla magna malignant tumors on the own material of the Division of Pathological Anatomy and Cytology of the Shalimov National Institute of Surgery and Transplantology. Materials and methods. Into the investigation 82 patients were included, to whom pancreaticoduodenectomy was performed for duodenal papilla magna malignant tumors in 2019 – 2021 yrs with further conduction of morphological analysis of the specimen excised. The average age of the patients have constituted (61.1 ± 8.1) yrs old. Results. There were revealed 8 histological types of the tumors, most frequent of them – adenocarcinomas of pancreatobiliary and intestinal types. These two variants were compared. They did not differ for the age and gender (р>0,05), but statistically significantly differed for the histological differentiation degree and tumoral spread: р =0.039 and р = 0.003, accordingly. Thus, in the pancreatobiliary type of adenocarcinoma the tumors with low differentiation level (G3) were in 1.9 times more frequent, than in adenocarcinomas of intestinal type: 22.9 and 11.8%, and in 2.8 times more frequently the more spread tumors were revealed (рТ3а–Т3b): 65.7 and 23.5%, accordingly. As well, in the patients with adenocarcinomas of pancreatobiliary type a positive status of regional lymph nodes was revealed more frequently – in 57.1%, than in patients with adenocarcinomas of intestinal type – 44.1%. Conclusion. Duodenal papilla magna malignant tumors – a heterogeneous group of tumors. Adenocarcinomas of pancreatobiliary and intestinal types are the most prevalent. Pancreatobiliary adenocarcinoma, as a histological type, is more aggressive, than intestinal adenocarcinoma.
目标。沙利莫夫国家外科与移植研究所病理解剖与细胞学部自体材料上十二指肠大乳头恶性肿瘤形态学特征的研究。材料和方法。本研究纳入82例患者,于2019 - 2021年行胰十二指肠切除术治疗十二指肠大乳头恶性肿瘤,并进一步对切除标本进行形态学分析。患者平均年龄为(61.1±8.1)岁。结果。肿瘤有8种组织学类型,以胰胆管腺癌和肠腺癌最为常见。对这两种变体进行比较。年龄和性别差异无统计学意义(p < 0.05),但组织学分化程度和肿瘤扩散差异有统计学意义(p < 0.05),分别为0.039和0.003。因此,胰胆管型腺癌中低分化水平(G3)肿瘤的发生率分别为肠型腺癌的22.9%和11.8%,是肠型腺癌的1.9倍,肿瘤的扩散率为2.8倍(рТ3а -Т3b),分别为65.7和23.5%。胰胆管型腺癌患者区域淋巴结阳性的发生率为57.1%,高于肠型腺癌患者的44.1%。结论。十二指肠大乳头恶性肿瘤-一组异质性肿瘤。胰胆管和肠道类型的腺癌是最常见的。胰胆管腺癌作为一种组织学类型,比肠腺癌更具侵袭性。
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引用次数: 0
History of organization of the specialized surgical aid to patients, suffering gastro–intestinal hemorrhage in the City of Dnipro 第聂伯罗市胃肠出血患者专业手术援助组织的历史
Pub Date : 2022-12-23 DOI: 10.26779/2522-1396.2022.7-8.70
V. Desyateryk
History of organization of the specialized surgical aid to patients, suffering gastro–intestinal hemorrhage in the City of Dnipro
第聂伯罗市胃肠出血患者专业手术援助组织的历史
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引用次数: 0
Simulation of prehepatic portal hypertension and impact of hepatic deportalization on its tissue 肝前门静脉高压症的模拟及肝去门化对其组织的影响
Pub Date : 2022-12-23 DOI: 10.26779/2522-1396.2022.7-8.35
О. Godik
Objective. On the prehepatic portal hypertension pattern, created by partial ligature of venae portae in rats, to estimate the impact of partial hepatic deportalization on its tissue. Materials and methods. The investigation was conducted on 35 male rats of a Wistar line, aged 4–6 weeks. In 15 laboratory animals the partial ligature of vena porta with formation of stenosis was conducted, and in 15 –false ligature, while the control group consisted of 5 intact laboratory animals. Results. There were revealed certain connections between conduction of partial ligature of vena porta and critical (lethal) lowering of portohepatic perfusion. The model of prehepatic portal hypertension, using partial ligature of vena porta, leading to partial lowering of portohepatic perfusion with development of cavernous transformation of vena porta and dystrophic changes in hepatocytes with further fibrous changes in hepatic parenchyma, was applied. Conclusion. The portal vein narrowing grade in range 52 – 59% constitutes the optimal one for the prehepatic portal hypertension formation with development of zonal adipose parenchymatous hepatic dystrophy and the balloon degeneration of hepatocytes with further development of fibroses in rats of a Wistar line aged 4 – 6 weeks.
目标。对大鼠部分门静脉结扎造成的肝前门静脉高压模式,评估部分肝去门化对其组织的影响。材料和方法。研究对象为Wistar系雄性大鼠35只,年龄4 ~ 6周龄。15只实验动物部分结扎门静脉形成狭窄,15只实验动物假结扎门静脉,对照组5只完整实验动物。结果。门静脉部分结扎的传导与肝门静脉灌注临界(致死)降低之间存在一定的联系。采用肝前门静脉高压症模型,部分结扎门静脉,导致肝门静脉灌注部分降低,门静脉海绵状转化,肝细胞营养不良,肝实质进一步纤维改变。结论。4 - 6周龄Wistar系大鼠肝前门脉高压形成伴带状脂肪实质性肝营养不良和肝细胞球囊变性伴纤维化发展的最佳分级为52 - 59%。
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引用次数: 0
Security and efficacy of intravenous injection of lidocaine in major hepatic resection 静脉注射利多卡因在大肝切除术中的安全性和有效性
Pub Date : 2022-12-14 DOI: 10.26779/2522-1396.2022.3-4.63
R. А. Zatsarynnyi, O. E. Sydiuk, O. Pidopryhora
Objective. To determine in dynamics the blood lidocaine concentration in the patients while performing major hepatic resection with its epidural and intravenous injection for intra– and postoperative anesthesia and to estimate the toxicity potential. Materials and methods. Into the investigation 27 patients were included, to whom hepatic resection with preservation of 30 – 60% of parenchyma was done. In all the patients multicomponent intraoperative anesthesia was applied. Depending on adjuvant used, the patients were divided into two groups: the first – 7 patients, in whom intravenous lidocaine injection was applied, and the second – 20 patients, in whom multicomponent anesthesia was added by thoracic epidural anesthesia. Results. In 2 h postoperatively a tendency towards enhanced blood concentration of lidocaine was observed by 28.8% after its epidural injection, comparing with intravenous injection – 2.37 and 1.84 mcg/ml (р=0.29) accordingly without principal difference in 14 h after the operation – 2.85 and 2.62 mcg/ml (р=0.76) accordingly. In no one patient toxic life–threatening reactions were registered. Conclusion. The adjuvant application of lidocaine for intra– and postoperative anesthesia, using intravenous and epidural introduction in major hepatic resection performance, do not lead to raising of the medicinal compound concentration in the blood higher than conventional toxic content. The blood concentration of the preparation while its epidural introduction may be higher, than in intravenous introduction, witnessing in favor of secureness of intravenous application of lidocaine and at the same time a statistically significant difference between indices of its concentration in various ways of introduction was not observed.
目标。目的:动态测定大肝切除术患者硬膜外和静脉注射利多卡因麻醉时的血药浓度,并评估其潜在毒性。材料和方法。纳入研究的27例患者均行肝切除术,保留了30 - 60%的肝实质。所有患者术中均采用多组分麻醉。根据辅助方式的不同,将患者分为两组:第一组- 7例,采用利多卡因静脉注射;第二组- 20例,在胸段硬膜外麻醉的基础上加用多组分麻醉。结果。术后2 h,硬膜外注射利多卡因血药浓度较静脉注射利多卡因升高28.8%,分别为2.37和1.84 mcg/ml (r =0.29),术后14 h利多卡因血药浓度分别为2.85和2.62 mcg/ml (r =0.76),无明显差异。没有一个病人出现危及生命的毒性反应。结论。辅助应用利多卡因进行内、术后麻醉,在大肝切除术中采用静脉及硬膜外引入表现,不导致血中药物化合物浓度高于常规毒性含量升高。该制剂在硬膜外引入时血药浓度可能高于静脉引入,有利于静脉应用利多卡因的安全性,同时不同引入方式的利多卡因浓度指标间无统计学差异。
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引用次数: 0
Changes in muscular wall of artificial bladder in experiment 人工膀胱肌壁变化的实验研究
Pub Date : 2022-12-14 DOI: 10.26779/2522-1396.2022.3-4.69
R. Savchuk, F. Kostyev, S. Golovko, O. M. Kolosov, A. Zadorognuk
Objective. To estimate morphometric changes of the artificial bladder muscular wall, which was formatted of terminal ileum, in experiment in early and late postoperative periods. Materials and methods. The investigation was conducted in the chronic experiment conditions on 22 mini-pigs, ageing from 16 to 19 mo. After performance of cystectomy to the animals the artificial bladder was formatted, using terminal ileum. In 3, 6 and 12 mo after the artificial bladder formation the animals were removed from the experiment. Results. Studying of thickness of longitudinal and circular muscular layers of artificial bladder in mini-pigs in 2 mo have shown its statistically meaningful enhancement, comparing with control value in 2,14 - (643.7 ± 53.1) mcm and 3.36 - (1358.11 ± 86.60) mcm times, accordingly, and the common muscular layer thickness have enhanced in 2.84 times – (2001.81 ± 143.40) mcm, caused by its hypertrophy. In 6 mo more intense processes of muscular wall hypertrophy were seen in artificial bladder of experimental animals: the longitudinal muscular layer thickness have had statistically significantly enhanced in 3.61 times, while of a circular one – in 5.42 times, and of a common - in 4.65 times. In 12 mo after ileocystoplasty in muscular wall of artificial bladder a statistically significant enhancement of longitudinal layer thickness was noted, comparing with according index of intact animals in 5.52 times, while a circular one – in 5.58, and a common – in 5.13 times. Conclusion. The main processes of the artificial bladder muscular wall hypertrophy occur during first 6 mo after its formation, especially intensively in period from 3 to 6 mo. In consequent six-month period  a statistically significant enhancement of the longitudinal muscle layer thickness of artificial bladder in 0.91 times was noted, comparing with according index in previous 6 mo and the indices of the longitudinal and circular muscle layers thickness, which did not differ statistically with according results of experimental investigations in previous 6 mo. The urine reservoir, formatted of the ileum part, was not accustomed for performance of new functions, because in its wall evolution and transformation occurs in a version of hypertrophy in longitudinal and circular layers as a result of the intestinal tube denervation and the urine impact.
目标。目的观察回肠末段人工膀胱肌壁在术后早期和后期的形态学变化。材料和方法。在慢性实验条件下对22头16 ~ 19月龄的小型猪进行了研究。在对动物进行膀胱切除术后,利用回肠末端形成人工膀胱。在人工膀胱形成后3、6和12个月,动物退出实验。结果。2月龄小型猪人工膀胱纵肌层厚度和圆形肌层厚度较对照组分别增加了2、14 -(643.7±53.1)mcm和3.36 -(1358.11±86.60)mcm倍,其中普通肌层厚度增加了2.84倍-(2001.81±143.40)mcm,这是由于人工膀胱肥大所致。6个月来,实验动物人工膀胱的肌壁增厚过程更为剧烈:纵向肌层厚度增加了3.61倍,圆形肌层厚度增加了5.42倍,普通肌层厚度增加了4.65倍。人工膀胱肌壁回肠成形术后12个月,纵层厚度增加了5.52倍,与完整动物相比增加了5.58倍,与普通动物相比增加了5.13倍。结论。人工膀胱肌壁肥厚的主要过程发生在其形成后的前6个月,3 ~ 6个月尤为明显。随后6个月,人工膀胱纵肌层厚度与前6个月的纵肌层厚度指数、纵肌层厚度指数和圆肌层厚度指数相比,增加了0.91倍,具有统计学意义。与前6个月的实验调查结果无统计学差异。回肠部分的尿库不适应新的功能,因为在其壁的演变和转化中,由于肠管去神经支配和尿液的影响,在纵向和圆形层发生肥大。
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引用次数: 0
Stress and surgical diseases of thyroid gland in environment of the armed conflict (review of literature and own observations) 武装冲突环境下甲状腺应激与外科疾病(文献综述和个人观察)
Pub Date : 2022-12-14 DOI: 10.26779/2522-1396.2022.3-4.73
O. Usenko, I. Khomenko, A. E. Kovalenko, R. Saliutin
Stress and surgical diseases of thyroid gland in environment of the armed conflict (review of literature and own observations)
武装冲突环境下甲状腺应激与外科疾病(文献综述和个人观察)
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引用次数: 1
Densitometric substantiation of the application regimes in a low-temperature electric welding of soft living tissues in phthisiosurgery 低温电焊接活体软组织在眼科手术中的应用
Pub Date : 2022-12-14 DOI: 10.26779/2522-1396.2022.3-4.29
E. Maietnyi
Objective. To determine the optimal regimes of application of a low-temperature electric welding of soft living tissues in formation of suture in pulmonary parenchyma, the pulmonary hilum preparation, and its lymph nodes ablation, basing on microbiological estimation of action of various regimes on the tuberculosis mycobacteria and densitometric indices of pulmonary parenchyma and to estimate its efficacy in far remote postoperative period. Materials and methods. The work is based on the results of postoperative investigations in 275 patients with the aim to determine the impact of a low-temperature electric welding of soft living tissues on pulmonary parenchyma and mediastinal lymph nodes. Results. There was established, that application of minimal automatic regime of a low-temperature electric welding of soft living tissues in phthisiosurgery guarantees effective elimination of microflora in 98.3% of patients. The revealed emphysematous processes and fibrous changes are occurring in parallel and essentially impacts the development of pulmonary-pleural complications. Conventional density of pulmonary parenchyma was noted in 57.5% of patients in the investigation group and in 49.7% patients of the control group. In both groups, the enhanced superdensity of pulmonary parenchyma in far remote postoperative period was not observed. Density of mediastinal lymph nodes was compared, and statistically significant difference between densitometric indices of mediastinal lymph nodes was absent. While application of a low-temperature electric welding of soft living tissues in minimal power regime of the complex there was noted essential characteristic as well: lesser rate of fibrous transformation of pulmonary parenchyma, than in the control group –  in 13.3 and 15.5%, accordingly. Conclusion. Application of a low-temperature electric welding of soft living tissues in phthisiosurgical interventions for the lymph nodes ablation have shown the presence of effective bactericidal regimes with preservation of lymphatic circulation, and low rigidity of pulmonary parenchyma in postoperative period. While a low-temperature electric welding of soft living tissues applied, the signs of lymphostasis, the lymphatic outflow disorders and pulmonary-pleural complications in postoperative period after phthisiosurgical interventions with the lymph node ablation procedure do not occur, as well as the risk of iatrogenic damages while performing dissection and excision of mediastinal lymph nodes.
目标。通过对不同方案对肺实质结核分枝杆菌和肺实质密度指标的微生物学评估,确定低温活体软组织电焊在肺实质缝合、肺门制备和淋巴结消融中的最佳应用方案,并评估其术后远期疗效。材料和方法。这项工作是基于275例患者的术后调查结果,目的是确定低温电焊软组织对肺实质和纵隔淋巴结的影响。结果。已有研究表明,在植牙外科手术中应用低温活体软组织最小自动焊接机制,可保证98.3%的患者有效消除微生物群。所显示的肺气肿突和纤维性改变是并行发生的,并在本质上影响肺-胸膜并发症的发展。研究组患者肺实质常规密度为57.5%,对照组为49.7%。两组术后远端均未见肺实质超密度增高。纵隔淋巴结密度比较,各纵隔淋巴结密度指标间差异无统计学意义。同时,在最小功率下应用低温电焊对软组织进行焊接,也有明显的基本特征:肺实质纤维转化率低于对照组,分别为13.3%和15.5%。结论。低温活体软组织电焊在淋巴结消融术中的应用表明,在保存淋巴循环和术后肺实质低刚性的情况下,存在有效的杀菌方案。在低温电焊接活体软组织的情况下,淋巴结消融手术后未出现淋巴停滞、淋巴流出障碍和肺胸膜并发症的迹象,以及在进行纵隔淋巴结清扫和切除时发生医源性损伤的风险。
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引用次数: 0
The methods of prophylaxis of the pancreatic fistula occurrence after pancreato–duodenectomy 预防胰十二指肠切除术后胰瘘发生的方法
Pub Date : 2022-12-14 DOI: 10.26779/2522-1396.2022.3-4.18
V. M. Kopchak, L. Pererva, R. Saliutin, V. Kropelnytskyi, I. Khomiak, O. Duvalko, V. P. Schkarban, Y. Khilko, V. Trachuk, V. Khanenko, A. O. Danyliuk
Objective. To elaborate the measures system, which permit to reduce the occurrence of pancreatic fistula and other severe complications after performance of pancreato–duodenectomy. Materials and methods. There were analyzed the results of treatment of 327 patients, in whom pancreato–duodenectomy was performed. In accordance to the scheme proposed, using the elaborated scale of risk for the postoperative pancreatic fistula occurrence with estimation of sarcopenia presence and application of certain prophylactic measures 98 patients were operated in period from November 2018 to December 2020 yr. (the main group). Into the control group 229 patients were included, operated on in the clinic from January 2015 to October 2018 yr. without estimation of risk for the pancreatic fistula occurrence and presence of sarcopenia. The method of pancreato–jejunoanastomosis formation was selected by operating surgeon. Results. Postoperative complications have occurred in 94 (41.0%) patients of the control group and in 28 (28.6%) patients of the main group (c 2 = 4.56, p=0.03). Clinically significant postoperative pancreatic fistula of B Degree have occurred in 9 (9.2%) patients of the main group, what was statistically significantly lower, than in the control group, in which postoperative pancreatic fistula of B or C Degree have occurred in 64 (27.9%) patients (c 2 = 11.6, p=0.0007). Lethality was 2.2% in the control group and 1.02% – in the main one. Conclusion. Introduction of the measures system elaborated have permitted to lower the postoperative pancreatic fistula rate statistically significantly from 27.9 to 9.2%, and of other postoperative complications – from 41.0 to 28.6% and lethality from 2.2 to 1.02%.
目标。探讨减少胰十二指肠切除术后胰瘘及其他严重并发症发生的措施体系。材料和方法。对327例行胰十二指肠切除术的患者的治疗结果进行了分析。根据提出的方案,在2018年11月至2020年12月期间(主组),采用拟定的胰瘘发生风险量表,评估肌少症的存在并采取一定的预防措施。对照组229例患者于2015年1月至2018年10月在诊所接受手术,未评估胰瘘发生风险和肌少症的存在。胰空肠吻合术由手术医师选择。结果。对照组术后并发症94例(41.0%),主组术后并发症28例(28.6%)(c2 = 4.56, p=0.03)。主组术后出现临床显著性B级胰瘘9例(9.2%),低于对照组64例(27.9%),差异有统计学意义(χ 2 = 11.6, p=0.0007)。对照组病死率为2.2%,主组病死率为1.02%。结论。该措施系统的引入使得术后胰瘘发生率从27.9%下降到9.2%,其他术后并发症发生率从41.0%下降到28.6%,致死率从2.2%下降到1.02%。
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引用次数: 1
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Klinicheskaia khirurgiia
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