Pub Date : 2022-12-14DOI: 10.26779/2522-1396.2022.3-4.87
S. Chooklin, S. Chuklin
Modern tactics for acute variceal bleeding in liver cirrhosis (Baveno VII guidelines)
肝硬化急性静脉曲张出血的现代治疗策略(Baveno VII指南)
{"title":"Modern tactics for acute variceal bleeding in liver cirrhosis (Baveno VII guidelines)","authors":"S. Chooklin, S. Chuklin","doi":"10.26779/2522-1396.2022.3-4.87","DOIUrl":"https://doi.org/10.26779/2522-1396.2022.3-4.87","url":null,"abstract":"Modern tactics for acute variceal bleeding in liver cirrhosis (Baveno VII guidelines)","PeriodicalId":17876,"journal":{"name":"Klinicheskaia khirurgiia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83037076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-14DOI: 10.26779/2522-1396.2022.3-4.40
A. Kot
Objective. To formulate clinic-morphological substantiation for application of calculated excision of excessive and pathologically changed parahernial tissues together with performance of improved abdominoplasty in surgical interventions in patients with hernias in conditions of ventral obesity. Materials and methods. The investigation is based on data of paraoperative examinations and own results of surgical treatment of 58 herniological patients. Rational methods of their operating are substantiated by patho- and morphometric characteristics, determined in accordance to the observed dimensions of ventral hernia deformation, and content of the fat-containing, fibrous-cicatricial and inflammatory-pathological components in it. Results. The program set «Statistica 6.1» was applied for elaboration of the results obtained. In accordance to own algorithm of the ventro- and sonometric investigations there was established, that the parahernial tissues extras in the patients with external hernias are localized and originated supraaponeurotically. Preoperative considerations concerning determination of optimal volumes of conduction of dermo- and fibro-lipectomies, performed before hernio-abdominoplasties on various hernias with signs of ventral obesity, have permitted to prevent the local purulent-inflammatory complications and to improve the indices of quality of life in the patient operated on. Conclusion. Application of the «with no surpluses» operating principle constitute a practical base for improvement of reconstructive-plastic interventions results in external abdominal hernias and a real component of the problem decision in medic-social and esthetic rehabilitation of herniological patients with obesity.
{"title":"Clinic-morphological substantiation of the parahernial tissues excision in hernio-abdominoplasty in patients with ventral obesity","authors":"A. Kot","doi":"10.26779/2522-1396.2022.3-4.40","DOIUrl":"https://doi.org/10.26779/2522-1396.2022.3-4.40","url":null,"abstract":"Objective. To formulate clinic-morphological substantiation for application of calculated excision of excessive and pathologically changed parahernial tissues together with performance of improved abdominoplasty in surgical interventions in patients with hernias in conditions of ventral obesity. \u0000Materials and methods. The investigation is based on data of paraoperative examinations and own results of surgical treatment of 58 herniological patients. Rational methods of their operating are substantiated by patho- and morphometric characteristics, determined in accordance to the observed dimensions of ventral hernia deformation, and content of the fat-containing, fibrous-cicatricial and inflammatory-pathological components in it. \u0000Results. The program set «Statistica 6.1» was applied for elaboration of the results obtained. In accordance to own algorithm of the ventro- and sonometric investigations there was established, that the parahernial tissues extras in the patients with external hernias are localized and originated supraaponeurotically. \u0000Preoperative considerations concerning determination of optimal volumes of conduction of dermo- and fibro-lipectomies, performed before hernio-abdominoplasties on various hernias with signs of ventral obesity, have permitted to prevent the local purulent-inflammatory complications and to improve the indices of quality of life in the patient operated on. \u0000Conclusion. Application of the «with no surpluses» operating principle constitute a practical base for improvement of reconstructive-plastic interventions results in external abdominal hernias and a real component of the problem decision in medic-social and esthetic rehabilitation of herniological patients with obesity.","PeriodicalId":17876,"journal":{"name":"Klinicheskaia khirurgiia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86933785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-23DOI: 10.26779/2522-1396.2022.9-10.10
V. Popov, O. Bolshak, V. Boukarim, О. M. Gurtovenko, O. M. Trembovetska
Objective. Elaboration of the correction methodology of mitral stenosis, complicated by massive thrombosis of left atrium, for improvement of immediate and late results of surgical treatment of this pathology. Materials and methods. Into the group analyzed 344 patients with mitral stenosis, complicated by massive thrombosis of left atrium, operated in Amosov National Institute of Cardiovascular Surgery in a period from 1 January 1984 yr to 1 January 2019 yr, were incorporated. In all the patients surgical correction of mitral stenosis and thrombectomy from left atrium was performed. In 161 (46.8%) patients a radical removal of thrombotic mass together with their base–lining was performed, while in 183 (53.2%) – without it. In 256 (74.4%) patients the left atrium auricle was ligated or resected, while in 88 (25.6%) – left intact. Results. The hospital lethality index have had directly proportionally raised with enhancement of degree of the left ventricle auricle: I – 0%, II – 3.9%, III – 5.1% (p<0.05). In a general group during all period of the investigation a directly proportional dependence of index of hospital lethality due to lethal thromboembolic complications on degree of massive thrombosis of the left atrium auricle was observed: I – 0.0%, II – 3.5%, III – 5.2% (p<0.05). Best indices of hospital lethality were achieved in radical removal of thrombi together with their base–lining with ligature or resection of the left atrium auricle as a possible origin of thrombi creation. Conclusion. While doing surgical correction in patients with massive thrombosis of left atrium it is important to remove the thrombotic base–lining and to ligate or resect the left atrium auricle, what significantly lowers the risk of hospital lethality, thromboembolic complications on stationary stage of treatment.
目标。阐述二尖瓣狭窄合并左心房大量血栓形成的矫正方法，以改善该病理手术治疗的即时和后期效果。材料和方法。本组纳入1984年1月1日至2019年1月1日在阿莫索夫国立心血管外科研究所手术的344例二尖瓣狭窄合并左心房血栓患者。所有患者均行二尖瓣狭窄手术矫正及左心房取栓术。161例(46.8%)患者进行了血栓性肿块根治性清除，183例(53.2%)患者没有进行根治性清除。256例(74.4%)患者左心房耳廓结扎或切除，88例(25.6%)患者左心房耳廓完整。结果。医院死亡率指数随左室-耳廓程度的增强成正比增加:I - 0%， II - 3.9%， III - 5.1% (p<0.05)。在所有调查期间，普通组致死性血栓栓塞并发症住院死亡率指数与左心房、耳廓大量血栓形成程度成正比关系:I - 0.0%， II - 3.5%， III - 5.2% (p<0.05)。医院死亡率的最佳指标是根治性清除血栓及其基础，结扎或切除左心房耳廓作为血栓形成的可能来源。结论。在对大量左心房血栓形成患者进行手术矫正时，重要的是去除血栓基础层，结扎或切除左心房耳廓，这可以显著降低住院死亡率和固定治疗阶段血栓栓塞并发症的风险。
{"title":"Surgical treatment of mitral stenosis, complicated by massive thrombosis of the left atrium: stationary stage","authors":"V. Popov, O. Bolshak, V. Boukarim, О. M. Gurtovenko, O. M. Trembovetska","doi":"10.26779/2522-1396.2022.9-10.10","DOIUrl":"https://doi.org/10.26779/2522-1396.2022.9-10.10","url":null,"abstract":"Objective. Elaboration of the correction methodology of mitral stenosis, complicated by massive thrombosis of left atrium, for improvement of immediate and late results of surgical treatment of this pathology. \u0000Materials and methods. Into the group analyzed 344 patients with mitral stenosis, complicated by massive thrombosis of left atrium, operated in Amosov National Institute of Cardiovascular Surgery in a period from 1 January 1984 yr to 1 January 2019 yr, were incorporated. In all the patients surgical correction of mitral stenosis and thrombectomy from left atrium was performed. In 161 (46.8%) patients a radical removal of thrombotic mass together with their base–lining was performed, while in 183 (53.2%) – without it. In 256 (74.4%) patients the left atrium auricle was ligated or resected, while in 88 (25.6%) – left intact. \u0000Results. The hospital lethality index have had directly proportionally raised with enhancement of degree of the left ventricle auricle: I – 0%, II – 3.9%, III – 5.1% (p<0.05). In a general group during all period of the investigation a directly proportional dependence of index of hospital lethality due to lethal thromboembolic complications on degree of massive thrombosis of the left atrium auricle was observed: I – 0.0%, II – 3.5%, III – 5.2% (p<0.05). Best indices of hospital lethality were achieved in radical removal of thrombi together with their base–lining with ligature or resection of the left atrium auricle as a possible origin of thrombi creation. \u0000Conclusion. While doing surgical correction in patients with massive thrombosis of left atrium it is important to remove the thrombotic base–lining and to ligate or resect the left atrium auricle, what significantly lowers the risk of hospital lethality, thromboembolic complications on stationary stage of treatment.","PeriodicalId":17876,"journal":{"name":"Klinicheskaia khirurgiia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72609628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-23DOI: 10.26779/2522-1396.2022.9-10.38
V. Kavyn
Clinical observation of nonoperated polydactylia of right hand
非手术性右手多指畸形临床观察
{"title":"Clinical observation of nonoperated polydactylia of right hand","authors":"V. Kavyn","doi":"10.26779/2522-1396.2022.9-10.38","DOIUrl":"https://doi.org/10.26779/2522-1396.2022.9-10.38","url":null,"abstract":"Clinical observation of nonoperated polydactylia of right hand","PeriodicalId":17876,"journal":{"name":"Klinicheskaia khirurgiia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78700631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-23DOI: 10.26779/2522-1396.2022.9-10.17
I. Shevchuk, M. Droniak, V. Droniak
Objective. To improve the results of surgical treatment in patients with postoperative peritonitis, using the certain algorithm proposed. Materials and methods. Prospective investigation was conducted on 244 patients, suffering postoperative peritonitis (the main group). In accordance to the peritoneal affection size the restricted postoperative peritonitis was present in 125 (51.2%) patients, and the extended one – in 119 (48.8%). Retrospective investigation consisted of studying of 212 cards of stationary patients, operated for postoperative peritonitis (the control group). Results. Miniinvasive operative reinterventions were done in 114 (46.7%) patients, suffering postoperative peritonitis, of them in 55 (48.2%) laparoscopic sanation and drainage of the peritoneal cavity abscess was used. In 19 (55.9%) of 34 patients with postoperative peritonitis in the interloop abscesses a laparoscopic sanation and drainage of the abscess were performed. Open operative interventions were performed in 130 (53.3%) patients. Conclusion. Application of the elaborated algorithm of the postoperative peritonitis surgical treatment have permitted to reduce the patients stationary stay from (14.2 ± 1.6) bed–days (control group) to (10.6 ± 1.2) bed–days (main group) and to reduce the lethality level from 31.6% (control group) to 18.4% (the main group).
{"title":"Algorithm of surgical treatment of postoperative peritonitis","authors":"I. Shevchuk, M. Droniak, V. Droniak","doi":"10.26779/2522-1396.2022.9-10.17","DOIUrl":"https://doi.org/10.26779/2522-1396.2022.9-10.17","url":null,"abstract":"Objective. To improve the results of surgical treatment in patients with postoperative peritonitis, using the certain algorithm proposed. \u0000Materials and methods. Prospective investigation was conducted on 244 patients, suffering postoperative peritonitis (the main group). In accordance to the peritoneal affection size the restricted postoperative peritonitis was present in 125 (51.2%) patients, and the extended one – in 119 (48.8%). Retrospective investigation consisted of studying of 212 cards of stationary patients, operated for postoperative peritonitis (the control group). \u0000Results. Miniinvasive operative reinterventions were done in 114 (46.7%) patients, suffering postoperative peritonitis, of them in 55 (48.2%) laparoscopic sanation and drainage of the peritoneal cavity abscess was used. In 19 (55.9%) of 34 patients with postoperative peritonitis in the interloop abscesses a laparoscopic sanation and drainage of the abscess were performed. Open operative interventions were performed in 130 (53.3%) patients. \u0000Conclusion. Application of the elaborated algorithm of the postoperative peritonitis surgical treatment have permitted to reduce the patients stationary stay from (14.2 ± 1.6) bed–days (control group) to (10.6 ± 1.2) bed–days (main group) and to reduce the lethality level from 31.6% (control group) to 18.4% (the main group).","PeriodicalId":17876,"journal":{"name":"Klinicheskaia khirurgiia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73113946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-23DOI: 10.26779/2522-1396.2022.9-10.29
S. O. Guryev, V. A. Kushnir
Objective. To determine the damage volume as a significant component of clinical–anatomical characteristic of traumas in the injured persons, who have obtained the trauma as a consequence of the traffic–transport accidents in the megapolis environment. Materials and methods. Retrospective analysis of data, concerning 1139 injured persons, who have got trauma as a consequence of the traffic–transport accidents in the City of Kyiv in the period 2019–2020 yrs. Results. There was established, that up to 70% of the injured persons have got a small volume of damage – with injuries of up to three anatomic–functional sites. Only 9% of such injured persons have got a big volume of trauma. The trauma volume have impacted the result of the traumatic process course with the discovered tendency for enhancement of part of the injured persons, obtaining negative result as a consequence of the trauma volume enhancement. Conclusion. Among the traumas, which were got by the injured persons as a consequence of the traffic–transport accidents in the megapolis environment, the restricted by volume trauma prevails – up to 75.42%. Injuries of four anatomic–functional sites as a consequence of the traffic–transport accidents constitute a critical volume of the damage obtained for these category of injured persons. The damage volume in the injured persons, who were traumatized due to the traffic–transport accidents depends immediately upon such factor as «the taking part in the injured person movement», while the biggest influence have demonstrated the factor of «taking part in the pedestrian movement». The factor, named as a «taking part in movement of the injured person» impacts immediately the result of the traumatic process course in any volume of the damage, and this influence is enhancing with the damage volume enhanced.
{"title":"Clinic–anatomical characteristic of the traffic–transport trauma in the megapolis environment First communication: the damage volume","authors":"S. O. Guryev, V. A. Kushnir","doi":"10.26779/2522-1396.2022.9-10.29","DOIUrl":"https://doi.org/10.26779/2522-1396.2022.9-10.29","url":null,"abstract":"Objective. To determine the damage volume as a significant component of clinical–anatomical characteristic of traumas in the injured persons, who have obtained the trauma as a consequence of the traffic–transport accidents in the megapolis environment. \u0000Materials and methods. Retrospective analysis of data, concerning 1139 injured persons, who have got trauma as a consequence of the traffic–transport accidents in the City of Kyiv in the period 2019–2020 yrs. \u0000Results. There was established, that up to 70% of the injured persons have got a small volume of damage – with injuries of up to three anatomic–functional sites. Only 9% of such injured persons have got a big volume of trauma. The trauma volume have impacted the result of the traumatic process course with the discovered tendency for enhancement of part of the injured persons, obtaining negative result as a consequence of the trauma volume enhancement. \u0000Conclusion. Among the traumas, which were got by the injured persons as a consequence of the traffic–transport accidents in the megapolis environment, the restricted by volume trauma prevails – up to 75.42%. Injuries of four anatomic–functional sites as a consequence of the traffic–transport accidents constitute a critical volume of the damage obtained for these category of injured persons. The damage volume in the injured persons, who were traumatized due to the traffic–transport accidents depends immediately upon such factor as «the taking part in the injured person movement», while the biggest influence have demonstrated the factor of «taking part in the pedestrian movement». The factor, named as a «taking part in movement of the injured person» impacts immediately the result of the traumatic process course in any volume of the damage, and this influence is enhancing with the damage volume enhanced.","PeriodicalId":17876,"journal":{"name":"Klinicheskaia khirurgiia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72952099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-23DOI: 10.26779/2522-1396.2022.9-10.34
I. V. Mykhalchishina, O. O. Deneka
Resectional–plastic approaches in treatment of chronic nonlactatonal mastitis
切除整形入路治疗慢性非哺乳期乳腺炎
{"title":"Resectional–plastic approaches in treatment of chronic nonlactatonal mastitis","authors":"I. V. Mykhalchishina, O. O. Deneka","doi":"10.26779/2522-1396.2022.9-10.34","DOIUrl":"https://doi.org/10.26779/2522-1396.2022.9-10.34","url":null,"abstract":"Resectional–plastic approaches in treatment of chronic nonlactatonal mastitis","PeriodicalId":17876,"journal":{"name":"Klinicheskaia khirurgiia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85871235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-23DOI: 10.26779/2522-1396.2022.9-10.03
V. Boyko, A. Serenko, D. Minukhin, V. H. Hroma, D. Yevtushenko, P. Korzh
Objective. To raise the efficacy of surgical treatment in patients, suffering chronic pulmonary abscesses, using miniinvasive electro–surgical technologies. Materials and methods. A single centre randomized controlled retro– and prospective investigation, which is based on analysis of the surgical treatment results in 78 patients, suffering chronic pulmonary abscesses, operated on base of the Zaytsev Institute of General and Urgent Surgery (Kharkiv) in a period from 2011 to 2021 yr. Results. Analysis of data of conducted dynamical instrumental control for efficacy in two different methods of treatment in patients, suffering chronic pulmonary abscesses, proves the enhanced efficacy of the treatment program proposed over the standard tactics. Conclusion. The methods of surgical interventions elaborated have permitted to impact in a positive and essential way the endogenous intoxication indices, to escape the resections performance, to lower the postoperative morbidity quantity, to prevent the adjacent organs injuries, to shorten a duration of clinical and social–labor rehabilitation of patients with achievement of stable positive effect.
{"title":"Treatment of chronic pulmonary abscesses with application of miniinvasive electrosurgical technologies","authors":"V. Boyko, A. Serenko, D. Minukhin, V. H. Hroma, D. Yevtushenko, P. Korzh","doi":"10.26779/2522-1396.2022.9-10.03","DOIUrl":"https://doi.org/10.26779/2522-1396.2022.9-10.03","url":null,"abstract":"Objective. To raise the efficacy of surgical treatment in patients, suffering chronic pulmonary abscesses, using miniinvasive electro–surgical technologies. \u0000Materials and methods. A single centre randomized controlled retro– and prospective investigation, which is based on analysis of the surgical treatment results in 78 patients, suffering chronic pulmonary abscesses, operated on base of the Zaytsev Institute of General and Urgent Surgery (Kharkiv) in a period from 2011 to 2021 yr. \u0000Results. Analysis of data of conducted dynamical instrumental control for efficacy in two different methods of treatment in patients, suffering chronic pulmonary abscesses, proves the enhanced efficacy of the treatment program proposed over the standard tactics. \u0000Conclusion. The methods of surgical interventions elaborated have permitted to impact in a positive and essential way the endogenous intoxication indices, to escape the resections performance, to lower the postoperative morbidity quantity, to prevent the adjacent organs injuries, to shorten a duration of clinical and social–labor rehabilitation of patients with achievement of stable positive effect.","PeriodicalId":17876,"journal":{"name":"Klinicheskaia khirurgiia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80391933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-23DOI: 10.26779/2522-1396.2022.9-10.41
O. Usenko, I. Khomenko, A. Kovalenko, I. P. Halochka, S. A. Andreieshchev, R. Saliutin, A. Varga, M. Bobryk
Surgical management of thyroid disease Clinical and practical recommendations
甲状腺疾病的外科治疗临床与实用建议
{"title":"Surgical management of thyroid disease Clinical and practical recommendations","authors":"O. Usenko, I. Khomenko, A. Kovalenko, I. P. Halochka, S. A. Andreieshchev, R. Saliutin, A. Varga, M. Bobryk","doi":"10.26779/2522-1396.2022.9-10.41","DOIUrl":"https://doi.org/10.26779/2522-1396.2022.9-10.41","url":null,"abstract":"Surgical management of thyroid disease Clinical and practical recommendations","PeriodicalId":17876,"journal":{"name":"Klinicheskaia khirurgiia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76600508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-23DOI: 10.26779/2522-1396.2022.9-10.22
I. Duzhyi, M. Kononenko, O. Sytnik, V. Shimko, O. Kravets, I. Medvedieva
Objective. To study the impact of antibacterial therapy on level of proteolytic enzymes on example of the neutrophils elastase, and clinical course of an acute pancreatitis. Materials and methods. There were investigated two groups of patients: in the main group (n=83) antibiotics were introduced by lymphotropic method, while in a control group (n=85) – in accordance to standard method. The content of the neutrophils elastase was determined in admittance day after 5 days of treatment. Results. In admittance to hospital the enzyme level in patients of both groups did not differ. After 5 days of antibacterial therapy the neutrophils elastase quantity have been reduced more after conduction of lymphotropic therapy than after the standard one. Reduction of level of the neutrophil elastase «deflected» have promoted the reduction of the pancreonecrosis infectioning, leading to reduction in the operative interventions quantity performed in the main group of patients (lymphotropic antibacterial therapy) in 2.1 times as well as their reconvalescence. Conclusion. Positive impact of lymphotropic antibacterial therapy towards «deflection» of proteolytic enzymes in the blood and on the acute pancreatitis course accordingly shows the reasons to recommend its application in this disease as an alternative to standard method.
{"title":"The enzymal substantiation of lymphotropic antibacterial therapy in an acute pancreatitis","authors":"I. Duzhyi, M. Kononenko, O. Sytnik, V. Shimko, O. Kravets, I. Medvedieva","doi":"10.26779/2522-1396.2022.9-10.22","DOIUrl":"https://doi.org/10.26779/2522-1396.2022.9-10.22","url":null,"abstract":"Objective. To study the impact of antibacterial therapy on level of proteolytic enzymes on example of the neutrophils elastase, and clinical course of an acute pancreatitis. \u0000Materials and methods. There were investigated two groups of patients: in the main group (n=83) antibiotics were introduced by lymphotropic method, while in a control group (n=85) – in accordance to standard method. The content of the neutrophils elastase was determined in admittance day after 5 days of treatment. \u0000Results. In admittance to hospital the enzyme level in patients of both groups did not differ. After 5 days of antibacterial therapy the neutrophils elastase quantity have been reduced more after conduction of lymphotropic therapy than after the standard one. Reduction of level of the neutrophil elastase «deflected» have promoted the reduction of the pancreonecrosis infectioning, leading to reduction in the operative interventions quantity performed in the main group of patients (lymphotropic antibacterial therapy) in 2.1 times as well as their reconvalescence. \u0000Conclusion. Positive impact of lymphotropic antibacterial therapy towards «deflection» of proteolytic enzymes in the blood and on the acute pancreatitis course accordingly shows the reasons to recommend its application in this disease as an alternative to standard method.","PeriodicalId":17876,"journal":{"name":"Klinicheskaia khirurgiia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87963815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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