Pub Date : 2022-06-30DOI: 10.5668/jehs.2022.48.3.159
D. Kang, Seok-won Jang, Si-won Lee, Jae-Hyun Lee, Sang Hee Lee, P. Kim, H. Chung, Chang-Ho Seong
{"title":"Applicability of QSAR Models for Acute Aquatic Toxicity under the Act on Registration, Evaluation, etc. of Chemicals in the Republic of Korea","authors":"D. Kang, Seok-won Jang, Si-won Lee, Jae-Hyun Lee, Sang Hee Lee, P. Kim, H. Chung, Chang-Ho Seong","doi":"10.5668/jehs.2022.48.3.159","DOIUrl":"https://doi.org/10.5668/jehs.2022.48.3.159","url":null,"abstract":"","PeriodicalId":17891,"journal":{"name":"Korean Journal of Environmental Health Sciences","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76532651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.5668/jehs.2022.48.3.167
Jae-Sik Ju, C. Park
{"title":"Application of Response Surface Methodology to Optimize the Performance of the Electro-Chlorination Process","authors":"Jae-Sik Ju, C. Park","doi":"10.5668/jehs.2022.48.3.167","DOIUrl":"https://doi.org/10.5668/jehs.2022.48.3.167","url":null,"abstract":"","PeriodicalId":17891,"journal":{"name":"Korean Journal of Environmental Health Sciences","volume":"202 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73107635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-30DOI: 10.5668/jehs.2022.48.2.59
Jihun Shin, Yong-Hui Choe, Dongjun Kim, Gihong Min, Jaemin Woo, Dongjun Kim, J. Shin, Mansu Cho, K. Sung, Jongdae Lee, Wonho Yang
{"title":"Evaluation of PM2.5 Exposure Contribution Using a Microenvironmental Model","authors":"Jihun Shin, Yong-Hui Choe, Dongjun Kim, Gihong Min, Jaemin Woo, Dongjun Kim, J. Shin, Mansu Cho, K. Sung, Jongdae Lee, Wonho Yang","doi":"10.5668/jehs.2022.48.2.59","DOIUrl":"https://doi.org/10.5668/jehs.2022.48.2.59","url":null,"abstract":"","PeriodicalId":17891,"journal":{"name":"Korean Journal of Environmental Health Sciences","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81928652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-30DOI: 10.5668/jehs.2022.48.2.106
G. Kim, Changyul Kim
ABSTRACT Background: Current research suggests that humans are exposed to microplastics through consumption of foods and beverages, the airway route, and a variety of other means. Objectives: We evaluated oxidative stress and inflammation from polyethylene microplastics (PE-MPs) in the neonatal liver through intragastric administration or intratracheal instillation in pregnant mice. Methods: PE-MPs were administered from gestational day 9 to postnatal day 7. The intragastric administration group (0.01 mg/mouse/day or 0.1 mg/mouse/day) and intratracheal instillation group (6 μ g/mouse/day or 60 μ g/mouse/day) of PE-MPs were administered. After sacrifice, the oxidative stress and inflammation of the neonatal livers were measured. Results: As a result of the oxidative stress caused by PE-MPs in the neonatal livers, glutathione peroxidase decreased in a concentration-dependent manner in the intragastric administration group compared to the control group and intratracheal instillation decreased in high concentration PE-MPs. The catalase level increased at high concentrations of intragastric administration and intratracheal instillation. To confirm the level of inflammation caused by PE-MPs, monocyte chemoattractant protein-1 and tumor necrosis factor-alpha were increased compared to the control group except for intratracheal intilation-high concentration PE-MPs. The C-reactive protein level was decreased by intragastric administration compared to the control group and intratracheal instillation was increased compared to the control group. Conclusions: Despite the difficulty in comparing the toxic intensity between intragastric administration and intratracheal instillation of PE-MPs, our study revealed that oxidative stress and inflammation were induced in the neonatal liver. However, it is necessary to evaluate the toxic effects of microplastics on various organs as well. Overall, the present study indicates that the evaluation of toxic effects of long-term microplastic exposure, potential of microplastic toxicity on next-generation offspring and toxicity mechanism in human should be considered for further investigations.
{"title":"Evaluation of Liver Toxicity of Neonates Following Intragastric Administration or Intratracheal Instillation of Polyethylene Microplatics to Pregnant Mice","authors":"G. Kim, Changyul Kim","doi":"10.5668/jehs.2022.48.2.106","DOIUrl":"https://doi.org/10.5668/jehs.2022.48.2.106","url":null,"abstract":"ABSTRACT Background: Current research suggests that humans are exposed to microplastics through consumption of foods and beverages, the airway route, and a variety of other means. Objectives: We evaluated oxidative stress and inflammation from polyethylene microplastics (PE-MPs) in the neonatal liver through intragastric administration or intratracheal instillation in pregnant mice. Methods: PE-MPs were administered from gestational day 9 to postnatal day 7. The intragastric administration group (0.01 mg/mouse/day or 0.1 mg/mouse/day) and intratracheal instillation group (6 μ g/mouse/day or 60 μ g/mouse/day) of PE-MPs were administered. After sacrifice, the oxidative stress and inflammation of the neonatal livers were measured. Results: As a result of the oxidative stress caused by PE-MPs in the neonatal livers, glutathione peroxidase decreased in a concentration-dependent manner in the intragastric administration group compared to the control group and intratracheal instillation decreased in high concentration PE-MPs. The catalase level increased at high concentrations of intragastric administration and intratracheal instillation. To confirm the level of inflammation caused by PE-MPs, monocyte chemoattractant protein-1 and tumor necrosis factor-alpha were increased compared to the control group except for intratracheal intilation-high concentration PE-MPs. The C-reactive protein level was decreased by intragastric administration compared to the control group and intratracheal instillation was increased compared to the control group. Conclusions: Despite the difficulty in comparing the toxic intensity between intragastric administration and intratracheal instillation of PE-MPs, our study revealed that oxidative stress and inflammation were induced in the neonatal liver. However, it is necessary to evaluate the toxic effects of microplastics on various organs as well. Overall, the present study indicates that the evaluation of toxic effects of long-term microplastic exposure, potential of microplastic toxicity on next-generation offspring and toxicity mechanism in human should be considered for further investigations.","PeriodicalId":17891,"journal":{"name":"Korean Journal of Environmental Health Sciences","volume":"139 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81413051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-30DOI: 10.5668/jehs.2022.48.2.86
Heejeong Seo, Kyoungwoo Min, Jiyoung Park, Juhyun Park, Hoyeon Hwang, Se-il Park, SeonJeong Kim, Suk-kyung Jeong, Seok-jin Bae, S. Kim
ABSTRACT Background: As high concentrations of uranium and radon have been detected in some areas in Korea, it is considered necessary to investigate natural radioactive materials in the Gwangju area. Objectives: This study aimed to identify the hydrochemical characteristics of groundwater in Gwangju and investigate the distribution characteristics of uranium and radon, which are naturally radioactive substances. Methods: To determine the uranium and radon concentrations in groundwater according to the geology of the Gwangju area, we measured 62 groundwater wells. A geological distribution map of uranium and radon content was prepared for this study. Results: The groundwater type, defined using a Piper diagram, was mainly Ca-HCO 3 . The concentration of uranium in the groundwater ranged from 0 to 29.3 µg/L, with a mean of 3.3 µg/L and a median of 0.9 µg/L. The median concentration of uranium in groundwater was highest in alluvium, granitic gneiss, and biotite granite (classified by geological unit), in that order. The concentration of radon in the groundwater ranged from 4.8 to 313.2 Bq/L, with a mean of 75.6 Bq/L and a median of 59.6 Bq/L. The median concentration of radon in groundwater was highest in biotite granite, alluvium, and granitic gneiss, in that order. As a result of the correlation analysis of groundwater in the study area, there was no significant correlation between uranium and radon. Conclusions: In this study area, uranium was shown to be far below the concentrations allowed by drinking water quality standards, but radon concentrations exceeded drinking water quality monitoring standards in 11% of the samples. It was judged that appropriate measures, such as the installation of radon reduction facilities, will be required after a thorough review of high-concentration radon detection sites of in the research area.
{"title":"Distribution Characteristics of Uranium and Radon Concentrations of Groundwater in Gwangju Area","authors":"Heejeong Seo, Kyoungwoo Min, Jiyoung Park, Juhyun Park, Hoyeon Hwang, Se-il Park, SeonJeong Kim, Suk-kyung Jeong, Seok-jin Bae, S. Kim","doi":"10.5668/jehs.2022.48.2.86","DOIUrl":"https://doi.org/10.5668/jehs.2022.48.2.86","url":null,"abstract":"ABSTRACT Background: As high concentrations of uranium and radon have been detected in some areas in Korea, it is considered necessary to investigate natural radioactive materials in the Gwangju area. Objectives: This study aimed to identify the hydrochemical characteristics of groundwater in Gwangju and investigate the distribution characteristics of uranium and radon, which are naturally radioactive substances. Methods: To determine the uranium and radon concentrations in groundwater according to the geology of the Gwangju area, we measured 62 groundwater wells. A geological distribution map of uranium and radon content was prepared for this study. Results: The groundwater type, defined using a Piper diagram, was mainly Ca-HCO 3 . The concentration of uranium in the groundwater ranged from 0 to 29.3 µg/L, with a mean of 3.3 µg/L and a median of 0.9 µg/L. The median concentration of uranium in groundwater was highest in alluvium, granitic gneiss, and biotite granite (classified by geological unit), in that order. The concentration of radon in the groundwater ranged from 4.8 to 313.2 Bq/L, with a mean of 75.6 Bq/L and a median of 59.6 Bq/L. The median concentration of radon in groundwater was highest in biotite granite, alluvium, and granitic gneiss, in that order. As a result of the correlation analysis of groundwater in the study area, there was no significant correlation between uranium and radon. Conclusions: In this study area, uranium was shown to be far below the concentrations allowed by drinking water quality standards, but radon concentrations exceeded drinking water quality monitoring standards in 11% of the samples. It was judged that appropriate measures, such as the installation of radon reduction facilities, will be required after a thorough review of high-concentration radon detection sites of in the research area.","PeriodicalId":17891,"journal":{"name":"Korean Journal of Environmental Health Sciences","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76543763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-30DOI: 10.5668/jehs.2022.48.2.116
Sueun Choi, Doseon Choi, Sung Jae Jang, SungJun Park, C. Yoon, Kiyoung Lee, Gwangpyo Ko, Cheonghoon Lee
ABSTRACT Background: The recent COVID-19 pandemic is one of the worst disease outbreaks of the 21th century. Due to a lack of reliable antiviral therapeutics, wearing face masks is recommended to prevent airborne infection originating from virus-contaminated bioaerosols. Objectives: The aim of this study was to evaluate the filtration efficiencies of face masks that are commercially available in South Korea for a biological aerosol of Staphylococcus aureus (S. aureus) and murine coronavirus, a well-known surrogate for human coronaviruses. Methods: We collected six different kinds of commercial masks: two Korea Filter (KF)94 (KF94-1, KF94-2) masks, one surgical (Surgical-1) mask, one anti-droplet (KF-AD-1) mask, and two dust (Dust-1, Dust-2) face masks. S. aureus (ATCC 6538), a well-performing test bacteria and murine coronavirus (ATCC VR-764) were prepared under a suitable culture condition. Then, a mask biological filtration tester was used to examine the microbial filtration efficiencies of masks. Test microorganisms were quantitatively measured via cultivation methods and microbial filtration efficiencies were calculated appropriately. Results: All face masks showed over 99.6% filtration efficiency for S. aureus or murine coronavirus. There were no significant differences among the bacterial filtration efficiencies of the face masks. KF94-1 (99.97±0.08%) and Dust-1 mask (99.97±0.07%) showed the highest (over 99.9%) filtration efficiency for murine coronavirus. KF94-1 or Dust-1 masks showed a significant virus filtration efficiency compared to Surgical-1 mask (p<0.05; Mann-Whitney U test). Conclusions: All the commercially available face masks used in this study can filter S. aureus or murine coronavirus in bioaerosols efficiently, regardless of the mask type. Therefore, our results suggest that wearing a certified face mask is a reliable means to prevent the transmission of infectious airborne diseases via biological aerosols.
背景:近期发生的2019冠状病毒病(COVID-19)大流行是21世纪最严重的疾病暴发之一。由于缺乏可靠的抗病毒治疗方法，建议戴口罩以防止由病毒污染的生物气溶胶引起的空气传播感染。目的:本研究的目的是评估韩国市售口罩对金黄色葡萄球菌(金黄色葡萄球菌)和小鼠冠状病毒(一种众所周知的人类冠状病毒替代品)生物气溶胶的过滤效率。方法:收集6种不同类型的商用口罩:韩国滤网(KF)94 (KF94-1、KF94-2)口罩2个，外科(surgical -1)口罩1个，防飞滴(KF- ad -1)口罩1个，粉尘(粉尘-1、粉尘-2)口罩2个。在适宜的培养条件下制备了金黄色葡萄球菌(ATCC 6538)、表现良好的试验菌和小鼠冠状病毒(ATCC VR-764)。然后，采用口罩生物过滤测试仪检测口罩的微生物过滤效率。通过培养法对受试微生物进行定量测定，适当计算微生物过滤效率。结果:所有口罩对金黄色葡萄球菌和小鼠冠状病毒的过滤率均在99.6%以上。不同口罩的细菌过滤效率无显著差异。KF94-1(99.97±0.08%)和Dust-1口罩(99.97±0.07%)对小鼠冠状病毒的过滤效率最高(99.9%以上)。KF94-1或Dust-1口罩与Surgical-1口罩相比具有显著的病毒过滤效率(p<0.05;曼-惠特尼检验)。结论:本研究中使用的所有市售口罩都能有效过滤生物气溶胶中的金黄色葡萄球菌或小鼠冠状病毒，与口罩类型无关。因此，我们的研究结果表明，佩戴经过认证的口罩是防止传染性空气传播疾病通过生物气溶胶的可靠手段。
{"title":"Filtration Efficiencies of Commercial Face Masks in Korea for Biological Aerosols","authors":"Sueun Choi, Doseon Choi, Sung Jae Jang, SungJun Park, C. Yoon, Kiyoung Lee, Gwangpyo Ko, Cheonghoon Lee","doi":"10.5668/jehs.2022.48.2.116","DOIUrl":"https://doi.org/10.5668/jehs.2022.48.2.116","url":null,"abstract":"ABSTRACT Background: The recent COVID-19 pandemic is one of the worst disease outbreaks of the 21th century. Due to a lack of reliable antiviral therapeutics, wearing face masks is recommended to prevent airborne infection originating from virus-contaminated bioaerosols. Objectives: The aim of this study was to evaluate the filtration efficiencies of face masks that are commercially available in South Korea for a biological aerosol of Staphylococcus aureus (S. aureus) and murine coronavirus, a well-known surrogate for human coronaviruses. Methods: We collected six different kinds of commercial masks: two Korea Filter (KF)94 (KF94-1, KF94-2) masks, one surgical (Surgical-1) mask, one anti-droplet (KF-AD-1) mask, and two dust (Dust-1, Dust-2) face masks. S. aureus (ATCC 6538), a well-performing test bacteria and murine coronavirus (ATCC VR-764) were prepared under a suitable culture condition. Then, a mask biological filtration tester was used to examine the microbial filtration efficiencies of masks. Test microorganisms were quantitatively measured via cultivation methods and microbial filtration efficiencies were calculated appropriately. Results: All face masks showed over 99.6% filtration efficiency for S. aureus or murine coronavirus. There were no significant differences among the bacterial filtration efficiencies of the face masks. KF94-1 (99.97±0.08%) and Dust-1 mask (99.97±0.07%) showed the highest (over 99.9%) filtration efficiency for murine coronavirus. KF94-1 or Dust-1 masks showed a significant virus filtration efficiency compared to Surgical-1 mask (p<0.05; Mann-Whitney U test). Conclusions: All the commercially available face masks used in this study can filter S. aureus or murine coronavirus in bioaerosols efficiently, regardless of the mask type. Therefore, our results suggest that wearing a certified face mask is a reliable means to prevent the transmission of infectious airborne diseases via biological aerosols.","PeriodicalId":17891,"journal":{"name":"Korean Journal of Environmental Health Sciences","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75858238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-30DOI: 10.5668/jehs.2022.48.2.75
J. Joen, Hyemin Lee, Seunghwan Lee, Jeong-Il Lee, C. Lee
ABSTRACT Background: Various types of semi-volatile organic compounds (SVOCs) exist in the public’s living environment. They occur in different forms in terms of their physical and chemical properties and partition coefficients. As a consequence, indoor exposure to SVOCs occurs via various routes, including inhalation of air and airborne particles, skin contact, and dust intake. Objectives: To propose a method for assessing human exposure to the SVOCs occurring in the air of an indoor environment, the concentrations of SVOCs in house dust and organic films measured in a real residential environment were estimated in terms of gas-phase concentration using the partition coefficient. Assessment of inhalation exposure to SVOCs was performed using this method. Methods: Phthalates were collected from samples of house dust and organic films from 110 households in a real residential environment. To perform an exposures assessment of the phthalates present in organic films, gas-phase concentration was calculated using the partition coefficient. The airborne gas-phase concentrations of phthalates from the house dust and organic films were estimated and exposure assessment was performed based on the assumption of inhalation exposure from air. Results: As a result of the exposure assessment for gas-phase phthalates from house dust and organic films, preschool children showed the highest level of inhalation of phthalates, followed by school children, adults, and adolescents. Conclusions: This study includes the limitation of not considering different SVOCs exposure pathways in the health impact assessment, including those of phthalates in the indoor living environment. However, this study has the significance of performing exposure assessment based on exposure to SVOCs present in indoor air that originated from organic films in the indoor residential environment. Therefore, the results of this study should be useful as basic data for exposure and health risk assessments of SVOCs associated with organic films in the indoor environment. ㆍ. Exposure assessment of SVOCs in the air required. ㆍ. Air phthalates were measured using house dust and organic films. ㆍ. Preschool children were the most exposed population. ㆍ. Dust and organic film could be used as a proxy for SVOC exposure via inhalation.
{"title":"Exposure Assessment of Phthalates from House Dust and Organic Films in the Indoor Environment","authors":"J. Joen, Hyemin Lee, Seunghwan Lee, Jeong-Il Lee, C. Lee","doi":"10.5668/jehs.2022.48.2.75","DOIUrl":"https://doi.org/10.5668/jehs.2022.48.2.75","url":null,"abstract":"ABSTRACT Background: Various types of semi-volatile organic compounds (SVOCs) exist in the public’s living environment. They occur in different forms in terms of their physical and chemical properties and partition coefficients. As a consequence, indoor exposure to SVOCs occurs via various routes, including inhalation of air and airborne particles, skin contact, and dust intake. Objectives: To propose a method for assessing human exposure to the SVOCs occurring in the air of an indoor environment, the concentrations of SVOCs in house dust and organic films measured in a real residential environment were estimated in terms of gas-phase concentration using the partition coefficient. Assessment of inhalation exposure to SVOCs was performed using this method. Methods: Phthalates were collected from samples of house dust and organic films from 110 households in a real residential environment. To perform an exposures assessment of the phthalates present in organic films, gas-phase concentration was calculated using the partition coefficient. The airborne gas-phase concentrations of phthalates from the house dust and organic films were estimated and exposure assessment was performed based on the assumption of inhalation exposure from air. Results: As a result of the exposure assessment for gas-phase phthalates from house dust and organic films, preschool children showed the highest level of inhalation of phthalates, followed by school children, adults, and adolescents. Conclusions: This study includes the limitation of not considering different SVOCs exposure pathways in the health impact assessment, including those of phthalates in the indoor living environment. However, this study has the significance of performing exposure assessment based on exposure to SVOCs present in indoor air that originated from organic films in the indoor residential environment. Therefore, the results of this study should be useful as basic data for exposure and health risk assessments of SVOCs associated with organic films in the indoor environment. ㆍ. Exposure assessment of SVOCs in the air required. ㆍ. Air phthalates were measured using house dust and organic films. ㆍ. Preschool children were the most exposed population. ㆍ. Dust and organic film could be used as a proxy for SVOC exposure via inhalation.","PeriodicalId":17891,"journal":{"name":"Korean Journal of Environmental Health Sciences","volume":"153 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79649406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-30DOI: 10.5668/jehs.2022.48.2.96
Y. Choi, K. Moon
Background: Pyrethroid insecticides account for more than 30% of the global insecticide market and are frequently used in agricultural settings and residential and public pest control among the general population. While several animal studies have suggested that exposure to pyrethroids can alter glucose homeostasis, there is only limited evidence of the association between environmental pyrethroid exposure and diabetes in humans. Objectives: This study aimed to report environmental 3-phenoxybenzoic acid (3-PBA) concentrations in urine and evaluate its association with the risk of diabetes in Korean adults. Methods: We analyzed data from the Korean National Environmental Health Survey (KoNEHS) Cycle 2 (2012~2014) and Cycle 3 (2015~2017). A total of 10,123 participants aged ≥19 years were included. Multiple logistic regressions were used to calculate the odds ratios (ORs) for diabetes according to log-transformed urinary 3-PBA levels. We also evaluated age, sex, education, monthly income, marital status, alcohol drinking, physical activity, urinary cotinine, body mass index, and sampling season as potential effect modifiers of these associations. Results: After adjusting for all the covariates, we found significant dose-response relationships between urinary 3-PBA as quartile and the prevalence of diabetes in pooled data of KoNEHS Cycles 2 and 3. In subgroup analyses, the adverse effects of pyrethroid exposure on diabetes were significantly stronger among those aged 19~39 years (p-interaction<0.001) and those who consumed high levels of cotinine (p-interaction= 0.020). Conclusions: Our findings highlight the potential diabetes risk of environmental exposure to pyrethroids and should be confirmed in large prospective studies in different populations in the future.
{"title":"Association between Urinary 3-Phenoxybenzoic Acid Concentrations and Self-Reported Diabetes in Korean Adults: Korean National Environmental Health Survey (KoNEHS) Cycle 2~3 (2012~2017)","authors":"Y. Choi, K. Moon","doi":"10.5668/jehs.2022.48.2.96","DOIUrl":"https://doi.org/10.5668/jehs.2022.48.2.96","url":null,"abstract":"Background: Pyrethroid insecticides account for more than 30% of the global insecticide market and are frequently used in agricultural settings and residential and public pest control among the general population. While several animal studies have suggested that exposure to pyrethroids can alter glucose homeostasis, there is only limited evidence of the association between environmental pyrethroid exposure and diabetes in humans. Objectives: This study aimed to report environmental 3-phenoxybenzoic acid (3-PBA) concentrations in urine and evaluate its association with the risk of diabetes in Korean adults. Methods: We analyzed data from the Korean National Environmental Health Survey (KoNEHS) Cycle 2 (2012~2014) and Cycle 3 (2015~2017). A total of 10,123 participants aged ≥19 years were included. Multiple logistic regressions were used to calculate the odds ratios (ORs) for diabetes according to log-transformed urinary 3-PBA levels. We also evaluated age, sex, education, monthly income, marital status, alcohol drinking, physical activity, urinary cotinine, body mass index, and sampling season as potential effect modifiers of these associations. Results: After adjusting for all the covariates, we found significant dose-response relationships between urinary 3-PBA as quartile and the prevalence of diabetes in pooled data of KoNEHS Cycles 2 and 3. In subgroup analyses, the adverse effects of pyrethroid exposure on diabetes were significantly stronger among those aged 19~39 years (p-interaction<0.001) and those who consumed high levels of cotinine (p-interaction= 0.020). Conclusions: Our findings highlight the potential diabetes risk of environmental exposure to pyrethroids and should be confirmed in large prospective studies in different populations in the future.","PeriodicalId":17891,"journal":{"name":"Korean Journal of Environmental Health Sciences","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80019029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-30DOI: 10.5668/jehs.2022.48.2.66
Hyemin Lee, Seung-Hyeon Lee, Jeong-In Jeon, Jeong-Il Lee, C. Lee
Background: The health effects of particulate matter (PM2.5) bonded with various harmful chemicals differ based on their composition, so investigating and managing their concentrations and composition is vital for long-term management. As industrial complexes emit considerable quantities of pollutants, higher PM2.5 concentrations and chemical component effects are expected than in other places. Objectives: We investigated the concentration distribution ratios of PM2.5 chemical components to provide basic data to inform future major emissions control and PM2.5 reduction measures in industrial complexes. Methods: We monitored five sites near the Ansan and Siheung industrial complexes from August 2020 to July 2021. Samples were collected and analyzed twice per week in spring/winter and once per week in summer/ autumn according to the National Institute of Environmental Research in the Ministry of Environments’ Air Pollution Monitoring Network Installation and Operation Guidelines. We investigated and compared composition ratios of 29 ions, carbon, and elemental components in PM2.5. Results: The analysis of PM2.5 components at the five sites revealed that ion components accounted for the greatest total mass at approximately 50% while carbon components and elemental components contributed 23~28% and 8~10%, respectively. Among the ionic components, NO3 – occupies the greatest proportion. OC occupies the greatest proportion of the carbon components and sulphur occupies the greatest proportion of elemental components. Conclusions: This study investigated the concentration distribution ratios of PM2.5 chemical components in industrial complexes. We believe these results provide basic chemical component concentration ratio data for establishing future air management policies and plans for the Ansan and Siheung industrial complexes.
{"title":"A Study on the Characteristics of Ion, Carbon, and Elemental Components in PM2.5 at Industrial Complexes in Ansan and Siheung","authors":"Hyemin Lee, Seung-Hyeon Lee, Jeong-In Jeon, Jeong-Il Lee, C. Lee","doi":"10.5668/jehs.2022.48.2.66","DOIUrl":"https://doi.org/10.5668/jehs.2022.48.2.66","url":null,"abstract":"Background: The health effects of particulate matter (PM2.5) bonded with various harmful chemicals differ based on their composition, so investigating and managing their concentrations and composition is vital for long-term management. As industrial complexes emit considerable quantities of pollutants, higher PM2.5 concentrations and chemical component effects are expected than in other places. Objectives: We investigated the concentration distribution ratios of PM2.5 chemical components to provide basic data to inform future major emissions control and PM2.5 reduction measures in industrial complexes. Methods: We monitored five sites near the Ansan and Siheung industrial complexes from August 2020 to July 2021. Samples were collected and analyzed twice per week in spring/winter and once per week in summer/ autumn according to the National Institute of Environmental Research in the Ministry of Environments’ Air Pollution Monitoring Network Installation and Operation Guidelines. We investigated and compared composition ratios of 29 ions, carbon, and elemental components in PM2.5. Results: The analysis of PM2.5 components at the five sites revealed that ion components accounted for the greatest total mass at approximately 50% while carbon components and elemental components contributed 23~28% and 8~10%, respectively. Among the ionic components, NO3 – occupies the greatest proportion. OC occupies the greatest proportion of the carbon components and sulphur occupies the greatest proportion of elemental components. Conclusions: This study investigated the concentration distribution ratios of PM2.5 chemical components in industrial complexes. We believe these results provide basic chemical component concentration ratio data for establishing future air management policies and plans for the Ansan and Siheung industrial complexes.","PeriodicalId":17891,"journal":{"name":"Korean Journal of Environmental Health Sciences","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90633729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-30DOI: 10.5668/jehs.2022.48.2.123
Y. Choi, G. Byun, Jong-Tae Lee
Background: The Environmental Health Action Program was a national project carried out from 2012~2021. It was aimed at developing public technologies to protect people's health from various environmental hazards. Objectives: One of the final goals of the project was “creating health benefits worth more than 179.2 billion won by reducing the environmental burden of disease.” This study aims to evaluate whether the program sufficiently achieved the planned benefits. Methods: In order to secure consistency in evaluation, we applied the same equation used in the goal-setting process. It is comprised of six parameters to estimate the benefit: 1. The amount of medical expenses for environmental diseases; 2. The attributable proportion of environmental risk factors’ 3. The rate of reduction in medical expenses for environmental diseases; 4. R&D project contribution; 5. The proportion of successful policy reflection; and 6. The contributions of the project. The corresponding variables were estimated at the end of the project, and the health benefits of the project were recalculated using the newly estimated variables. Results: It was estimated that a total of 195 billion won in health benefits occurred or will occur from 2015 to 2026. The main contributors for achieving the target were an increase in medical expenses for environmental diseases, a high score in the R&D project contribution, and the proportion of successful policy reflection. Conclusions: Technically, the equation used in the project is about medical expenses for environmental diseases rather than about the environmental burden of disease. There are several benefits of using the environmental burden of disease in the evaluation of public health policies. In further studies, developing a policy evaluation framework using indicators such as population attributable fraction would be needed.
{"title":"Evaluation of Health Benefit from the Environmental Health Action Program Based on the Environmental Burden of Disease","authors":"Y. Choi, G. Byun, Jong-Tae Lee","doi":"10.5668/jehs.2022.48.2.123","DOIUrl":"https://doi.org/10.5668/jehs.2022.48.2.123","url":null,"abstract":"Background: The Environmental Health Action Program was a national project carried out from 2012~2021. It was aimed at developing public technologies to protect people's health from various environmental hazards. Objectives: One of the final goals of the project was “creating health benefits worth more than 179.2 billion won by reducing the environmental burden of disease.” This study aims to evaluate whether the program sufficiently achieved the planned benefits. Methods: In order to secure consistency in evaluation, we applied the same equation used in the goal-setting process. It is comprised of six parameters to estimate the benefit: 1. The amount of medical expenses for environmental diseases; 2. The attributable proportion of environmental risk factors’ 3. The rate of reduction in medical expenses for environmental diseases; 4. R&D project contribution; 5. The proportion of successful policy reflection; and 6. The contributions of the project. The corresponding variables were estimated at the end of the project, and the health benefits of the project were recalculated using the newly estimated variables. Results: It was estimated that a total of 195 billion won in health benefits occurred or will occur from 2015 to 2026. The main contributors for achieving the target were an increase in medical expenses for environmental diseases, a high score in the R&D project contribution, and the proportion of successful policy reflection. Conclusions: Technically, the equation used in the project is about medical expenses for environmental diseases rather than about the environmental burden of disease. There are several benefits of using the environmental burden of disease in the evaluation of public health policies. In further studies, developing a policy evaluation framework using indicators such as population attributable fraction would be needed.","PeriodicalId":17891,"journal":{"name":"Korean Journal of Environmental Health Sciences","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86573397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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