Pub Date : 2022-05-01DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5249
Y. Moreno Caro, W. Weiner, L. Naser, W.G. Grischo, M. Kala, L. Hecker, T. Wang, K. Knox, T. Marlowe
{"title":"Novel Non-Catalytic FAK Inhibition Downregulates Lung Fibroblast Matrix Production","authors":"Y. Moreno Caro, W. Weiner, L. Naser, W.G. Grischo, M. Kala, L. Hecker, T. Wang, K. Knox, T. Marlowe","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5249","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5249","url":null,"abstract":"","PeriodicalId":179165,"journal":{"name":"D30. THE INJURED LUNG: MECHANISMS AND THERAPEUTIC TARGETS","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117018465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5253
J. Gagan, D. M. Dane, C. Hsia
{"title":"Delivery of Soluble Klotho cDNA to the Lung Alleviates Acute Lung Injury","authors":"J. Gagan, D. M. Dane, C. Hsia","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5253","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5253","url":null,"abstract":"","PeriodicalId":179165,"journal":{"name":"D30. THE INJURED LUNG: MECHANISMS AND THERAPEUTIC TARGETS","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125151433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5255
T. Kim, Y. Xin, K. Martin, H. Song, A. Lenart, S. Gerard, M. Petrov, J. Shen, K. Rozenberg, J. Herrmann, L. Staelin, S. Humayun, P. Shah, U. Sidhu, S. Bathula, K. Reutlinger, M. Staley, P. Delvecchio, J. Barakat, S. Sarfaraz-Khan, I. Duncan, L. Berra, R. Rizi, M. Cereda
{"title":"Comparison of Dynamic Contrast Enhancement Computed Tomography Analysis Models to Characterize Pulmonary Blood Flow in a Pig Model of ARDS","authors":"T. Kim, Y. Xin, K. Martin, H. Song, A. Lenart, S. Gerard, M. Petrov, J. Shen, K. Rozenberg, J. Herrmann, L. Staelin, S. Humayun, P. Shah, U. Sidhu, S. Bathula, K. Reutlinger, M. Staley, P. Delvecchio, J. Barakat, S. Sarfaraz-Khan, I. Duncan, L. Berra, R. Rizi, M. Cereda","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5255","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5255","url":null,"abstract":"","PeriodicalId":179165,"journal":{"name":"D30. THE INJURED LUNG: MECHANISMS AND THERAPEUTIC TARGETS","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127743488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5245
M. Nizamoglu, T. Koster, M. Thomas, W. Timens, C. Koss, K. E. El Kasmi, B. Melgert, I. Heijink, J. Burgess
{"title":"3D Fibrotic Lung Extracellular Matrix Hydrogels Trigger Pro-Fibrotic Responses in Primary Lung Fibroblasts","authors":"M. Nizamoglu, T. Koster, M. Thomas, W. Timens, C. Koss, K. E. El Kasmi, B. Melgert, I. Heijink, J. Burgess","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5245","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5245","url":null,"abstract":"","PeriodicalId":179165,"journal":{"name":"D30. THE INJURED LUNG: MECHANISMS AND THERAPEUTIC TARGETS","volume":"206 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115784392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5251
G. Cosgrove, M. Decaris, S. Wong, E. Park, S. Turner, E. Adegbite, E. Lefebvre
{"title":"PLN-74809, an Oral, Dual-Selective αvβ6/αvβ1 Inhibitor in Phase 2 Clinical Trials for Idiopathic Pulmonary Fibrosis (IPF), Sustainably Reduces Transforming Growth Factor Beta (TGF-β) Activity in the Lungs of Healthy Participants with Once-Daily Dosing","authors":"G. Cosgrove, M. Decaris, S. Wong, E. Park, S. Turner, E. Adegbite, E. Lefebvre","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5251","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5251","url":null,"abstract":"","PeriodicalId":179165,"journal":{"name":"D30. THE INJURED LUNG: MECHANISMS AND THERAPEUTIC TARGETS","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131727518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}