Hepatitis medical care coordinators (HMCCs) in Japan are trained by local governments and regional core centers, and are expected to play an active role in various aspects of hepatitis countermeasures. A 2019 survey revealed varied activity statuses of HMCCs among facilities. This study surveyed the present status of HMCCs in 21 of the 72 regional core centers in the fiscal year 2021.
{"title":"肝疾患診療連携拠点病院における肝炎医療コーディネーターの現状（第2報）","authors":"Hiroshi Isoda, Masaru Enomoto, Hirokazu Takahashi, Takashi Oono, Taisuke Inoue, Tadashi Ikegami, Tatsuya Ide, Yoshio Tokumoto, Koji Ogawa, Hiroko Setoyama, Yoshihito Uchida, Masami Hashimoto, Kenichi Hirota, Satoru Kakizaki, Sachiko Tatsuki, Takako Inoue, Mizuki Endo, Tetsuro Shimakami, Yoshihisa Arao, Jun Inoue, Atsushi Suetsugu, Kenji Nagata, Masaaki Korenaga","doi":"10.2957/kanzo.64.510","DOIUrl":"https://doi.org/10.2957/kanzo.64.510","url":null,"abstract":"Hepatitis medical care coordinators (HMCCs) in Japan are trained by local governments and regional core centers, and are expected to play an active role in various aspects of hepatitis countermeasures. A 2019 survey revealed varied activity statuses of HMCCs among facilities. This study surveyed the present status of HMCCs in 21 of the 72 regional core centers in the fiscal year 2021.","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"188 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135663610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A questionnaire survey of medical institutions Chiba Prefecture, Japan, specializing in liver diseases was conducted. This study aimed to provide an overview of the current hepatitis virus tests situations and measures taken to link test-positive individuals to specialists. The positivity rate in these institutions was high, with 2.2% for hepatitis C antibody (HCVAb) and 0.9% for hepatitis B surface antigen (HBsAg). Although many institutions (70%) had been employing linking measures, the consultation rate with hepatologists was low, with 7.6% and 14.3% for HCVAb- and for HBsAg-positive cases, respectively. Only half of the institutions disclosed that their measures were working well. These data suggested the importance of improving the system for determining test-positive individuals and promoting hepatologist consultation.
{"title":"Situation of hepatitis virus tests and measures to link test-positive individuals to specialists: a survey of institutions in Chiba, Japan, specializing in liver diseases","authors":"Masato Nakamura, Soichiro Kiyono, Kentaro Fujimoto, Tadayoshi Kogure, Sae Yumita, Keita Ogawa, Terunao Iwanaga, Miyuki Nakagawa, Kisako Fujiwara, Hiroaki Kanzaki, Keisuke Koroki, Masanori Inoue, Kazufumi Kobayashi, Naoya Kanogawa, Takayuki Kondo, Sadahisa Ogasawara, Ryo Nakagawa, Shingo Nakamoto, Ryosuke Muroyama, Jun Kato, Naoya Kato","doi":"10.2957/kanzo.64.517","DOIUrl":"https://doi.org/10.2957/kanzo.64.517","url":null,"abstract":"A questionnaire survey of medical institutions Chiba Prefecture, Japan, specializing in liver diseases was conducted. This study aimed to provide an overview of the current hepatitis virus tests situations and measures taken to link test-positive individuals to specialists. The positivity rate in these institutions was high, with 2.2% for hepatitis C antibody (HCVAb) and 0.9% for hepatitis B surface antigen (HBsAg). Although many institutions (70%) had been employing linking measures, the consultation rate with hepatologists was low, with 7.6% and 14.3% for HCVAb- and for HBsAg-positive cases, respectively. Only half of the institutions disclosed that their measures were working well. These data suggested the importance of improving the system for determining test-positive individuals and promoting hepatologist consultation.","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"205 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135663605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Results of a questionnaire survey on career support, role of academic societies, and social networking -Questionnaire at the 44th meeting of the eastern branch of Japan Society of Hepatology-","authors":"Miyako Murakawa, Kyoko Hoshikawa, Mina Nakagawa, Satoshi Tanaka, Sachiyo Yoshio, Goki Suda, Kazumichi Abe, Hidekatsu Kuroda, Hiroko Iijima","doi":"10.2957/kanzo.64.476","DOIUrl":"https://doi.org/10.2957/kanzo.64.476","url":null,"abstract":"第44回日本肝臓学会東部会のキャリア支援・ダイバーシティ推進委員会関連企画の一環として，学会参加者を対象にキャリア支援・学会・SNSに関するアンケート調査を実施し，238名（男性78%，女性22%，40歳未満21%）から回答を得た．「希望するキャリアを継続する際の大きな障害」について最多回答は「時間的な余裕」（61%），次いで「支援体制の不備」（43%）であり，「キャリア支援・ダイバーシティ推進において重要だと思うこと」は「働く環境の整備」（58％）が最多だった．また，学位の取得や留学については肯定的な意見が多かった（学位81%，留学75%）．必要な学会の取り組みとしては，学術集会・教育講演会のハイブリッド開催（74%）や単位更新のweb化（51%）の要望が多かった．さらにSNSを利用している割合はFacebook 44%，Twitter 32％であり，Twitterは若い年代で多かった．","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"186 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135663436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We report a case of hepatocellular carcinoma with high mesenchymal-epithelial transition (MET) gene amplification demonstrating significant tumor shrinkage after cabozantinib treatment. A male patient in his fifties had far-advanced hepatocellular carcinoma and had previously been treated with combination therapy of lenvatinib or atezolizumab plus bevacizumab but had experienced progressive disease. We conducted FoundationOne® CDx, which is a comprehensive genomic profiling test, considering the next-line efficacious treatment options, and we confirmed high copy MET gene amplification. Hence, we administered cabozantinib, which caused a significant reduction in the tumor size. This case highlights the potential of comprehensive genomic profiling in identifying efficacious drugs and emphasizes the importance of actively conducting genomic testing to improve treatment outcomes.
{"title":"カボザンチニブ投与により著明に腫瘍縮小を認めたMET遺伝子増幅を伴う肝細胞癌の1例","authors":"Satoru Hagiwara, Kazuomi Ueshima, Naoshi Nishida, Masatoshi Kudo","doi":"10.2957/kanzo.64.514","DOIUrl":"https://doi.org/10.2957/kanzo.64.514","url":null,"abstract":"We report a case of hepatocellular carcinoma with high mesenchymal-epithelial transition (MET) gene amplification demonstrating significant tumor shrinkage after cabozantinib treatment. A male patient in his fifties had far-advanced hepatocellular carcinoma and had previously been treated with combination therapy of lenvatinib or atezolizumab plus bevacizumab but had experienced progressive disease. We conducted FoundationOne® CDx, which is a comprehensive genomic profiling test, considering the next-line efficacious treatment options, and we confirmed high copy MET gene amplification. Hence, we administered cabozantinib, which caused a significant reduction in the tumor size. This case highlights the potential of comprehensive genomic profiling in identifying efficacious drugs and emphasizes the importance of actively conducting genomic testing to improve treatment outcomes.","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"131 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135663606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Strategic International Session","authors":"","doi":"10.2957/kanzo.64.a533","DOIUrl":"https://doi.org/10.2957/kanzo.64.a533","url":null,"abstract":"","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139338221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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