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[Surgical Treatment of Hypopharyngeal Carcinoma, Neck Dissection and Adjuvant Postoperative Therapy of Oropharyngeal and Hypopharyngeal Cancer: Recommendations of the current S3 Guideline - Part II]. [下咽癌的手术治疗、颈部切除术以及口咽癌和下咽癌的术后辅助治疗:现行S3指南的建议--第二部分]。
IF 0.9 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-10-01 DOI: 10.1055/a-2223-4098
Andreas Dietz, Matthäus Stöhr, Veit Zebralla, Markus Pirlich, Susanne Wiegand, Nils H Nicolay

Part II of the S3 guideline report deals with the surgical treatment of hypopharyngeal carcinoma, neck dissection for oropharyngeal and hypopharyngeal carcinomas and adjuvant therapy options. Primary surgical therapy ± adjuvant radio- or radiochemotherapy and primary radio- or radiochemotherapy are established as primary therapies for local-regional hypopharyngeal carcinomas. Direct randomized comparisons of both basic therapeutic procedures were never conducted. Available registry data show a worse prognosis of hypopharyngeal carcinoma compared to oropharyngeal carcinomas in all locoregional tumor stages, regardless of the treatment method. For T1N0-T2N0 squamous cell carcinoma of the hypopharynx, there are no relevant differences in overall survival and locoregional relapse rate between primary surgical and primary non-surgical treatment. Primary surgical therapy ± adjuvant radiotherapy or radiochemotherapy and primary radiotherapy or radiochemotherapy are established as primary therapies for advanced but locoregionally limited hypopharyngeal carcinomas. Neck dissection is an integral part of the primary surgical treatment of oropharyngeal and hypopharyngeal cancer. There are only a few randomized studies on non-surgical organ preservation for advanced hypopharyngeal cancer as an alternative to pharyngolaryngectomy, but these have led to the recommendation of alternative concepts in the new guideline. The indication and implementation of postoperative adjuvant radiotherapy and radiochemotherapy for hypopharyngeal carcinoma do not differ from those for HPV/p16-negative and -positive oropharyngeal carcinoma.

S3指南报告的第二部分涉及下咽癌的手术治疗、口咽癌和下咽癌的颈部切除术以及辅助治疗方案。原发性手术治疗±辅助放射或放化疗和原发性放射或放化疗是治疗局部区域性下咽癌的主要疗法。这两种基本治疗方法从未进行过直接的随机比较。现有的登记数据显示,与口咽癌相比,下咽癌在所有局部区域肿瘤分期中的预后都较差,与治疗方法无关。对于 T1N0-T2N0 下咽鳞状细胞癌,初次手术治疗和初次非手术治疗在总生存率和局部复发率方面没有相关差异。原发手术治疗±辅助放疗或放射化疗和原发放疗或放射化疗已被确定为晚期但局部局限性下咽癌的原发疗法。颈部切除是口咽癌和下咽癌初级手术治疗不可或缺的一部分。关于晚期下咽癌的非手术器官保留替代咽喉切除术的随机研究为数不多,但这些研究促使新指南推荐了替代概念。下咽癌术后辅助放疗和放射化疗的适应症和实施方法与HPV/p16阴性和阳性口咽癌并无不同。
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引用次数: 0
Kommentar zu „Nasopharynxkarzinom: künstliche Intelligenz zur Prognosebestimmung“. 就 "鼻咽癌:人工智能的预后判断 "发表评论。
IF 0.9 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-10-01 DOI: 10.1055/a-2359-5657
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引用次数: 0
[Short-term quality of life assessment after sinus surgery for chronic rhinosinusitis]. [慢性鼻窦炎鼻窦手术后短期生活质量评估]。
IF 0.9 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-10-01 Epub Date: 2024-05-16 DOI: 10.1055/a-2306-2702
Michaela Maria Plath, Matthias Sand, Mark-Philip Gruchlik, Carlo Cavaliere, Sara Friauf, Peter Plinkert, Karim Plath, Ingo Baumann

Background: Chronic rhinosinusitis (CRS) has a negative impact on health-related quality of life (HRQoL). Functional endoscopic sinus surgery (FESS) is the treatment of choice for those not responding to medical treatments. To date, the short-term effects of FESS on HRQoL are still unclear.

Objective: Evaluation of the short-term effects of FESS on HRQoL in CRS patients using the SNOT-22 questionnaire.

Methods: The results of the validated German version of the Sino-Nasal Outcome Test-22 (SNOT-22) questionnaire were analysed from 89 patients with CRS before surgery and 10-14 days (n = 77), four (n = 77), six weeks (n = 76) and 6 months (n = 71) after FESS, and compared with those of 1,000 healthy controls selected using a non-probability quota sample in accordance to the distribution of the German Microcensus.

Results: Compared to the preoperative mean SNOT-22 score (47.35), CRS patients significantly improved in HRQoL 10-14 days (31.75, p < 0.01), 4 weeks (25.84, p < 0.01), 6 weeks (24.16, p < 0.01) and 6 months after FESS (27.16, p < 0.01). Pre- and 6 months postoperatively, the five most important SNOT-22 items were nasal obstruction, smell and taste reduction, thick, mucous nasal secretions, need to blow the nose and postnasal drip. At the 2, 4 and 6-week follow-up, the reduction in smell and taste was most frequently perceived as limiting the HRQoL.

Conclusions: This follow-up study shows for the first time that the reduction in smell and taste should be treated and controlled concervatively in the short term after FESS.

背景:慢性鼻窦炎(CRS)对健康相关生活质量(HRQoL)有负面影响。功能性内窥镜鼻窦手术(FESS)是药物治疗无效者的首选治疗方法。迄今为止,FESS 对 HRQoL 的短期影响仍不明确:使用 SNOT-22 问卷评估 FESS 对 CRS 患者 HRQoL 的短期影响:方法:对89名CRS患者术前、FESS术后10-14天(77人)、4天(77人)、6周(76人)和6个月(71人)的Sino-Nasal Outcome Test-22(SNOT-22)问卷德文版的有效结果进行分析,并与根据德国微观人口普查分布采用非概率配额抽样法选出的1000名健康对照者的结果进行比较:与术前的平均 SNOT-22 评分(47.35)相比,CRS 患者在 FESS 术后 10-14 天(31.75,p < 0.01)、4 周(25.84,p < 0.01)、6 周(24.16,p < 0.01)和 6 个月后的 HRQoL 均有明显改善(27.16,p < 0.01)。术前和术后 6 个月,SNOT-22 中最重要的五个项目是鼻阻塞、嗅觉和味觉减退、鼻腔分泌物粘稠、需要擤鼻涕和鼻后滴流。在 2 周、4 周和 6 周的随访中,嗅觉和味觉减退最常被认为是限制 HRQoL 的因素:这项随访研究首次表明,在鼻内镜手术后的短期内,嗅觉和味觉的减退应得到治疗和控制。
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引用次数: 0
Fall Invertiertes Papillom. 倒置乳头状瘤病例
IF 0.9 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-10-01 DOI: 10.1055/a-2347-7779
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引用次数: 0
Nasopharynxkarzinom: künstliche Intelligenz zur Prognosebestimmung. 鼻咽癌:用人工智能确定预后。
IF 0.9 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-10-01 DOI: 10.1055/a-2359-5632
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引用次数: 0
[Sinunasal surgery as outpatient procedure with special consideration of nasal packing - Position paper of the German Society of Otorhinolaryngology, Head and Neck Surgery, the working group Rhinology / Rhinosurgery (ARHIN) of the German Society of Otorhinolaryngology, Head and Neck Surgery and German Professional Association of Otorhinolaryngologists]. [鼻窦手术作为门诊手术,特别考虑鼻腔填料--德国耳鼻咽喉头颈外科学会、德国耳鼻咽喉头颈外科学会鼻科/鼻外科工作组(ARHIN)和德国耳鼻咽喉科医师专业协会的立场文件]。
IF 0.9 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-09-30 DOI: 10.1055/a-2353-2347
Rainer K Weber, Thomas Deitmer, Jan Löhler, Christoph Aletsee, Ingo Baumann, Christian Betz, Achim Beule, Robert Böscke, Andreas Dietz, Vanessa Harnischmacher, Frank Haubner, Werner Heppt, Anna Sophie Hoffmann, Thomas K Hoffmann, Werner Hosemann, Thomas Kuehnel, Martin Laudien, Bernhard Olzowy, Kim-Victoria Seibert, Fabian Sommer, Thomas Verse, Susanne Wiegand, Tanja Hildenbrand

Objective: Currently, there is an intensive discussion on advancing and expanding outpatient rhinosurgical procedures. Many questions about how to stratify into out- and inpatient procedures are still not sufficiently clarified. Particularly, the use of nasal packing materials is not adequately discussed.

Material and methods: Development of a checklist to stratify sinunasal procedures into in- or outpatient procedures with consideration of current scientific literature and risk factors.

Results and conclusions: After comprehensive assessment of the literature and analysis of specific risk factors, a list of sinunasal procedures is presented, which should be performed as inpatient procedures. We present a checklist for in- and outpatient sinunasal procedures, which considers social, medical and surgical factors as well as the use of nasal packing materials. Furthermore, a checklist is added to assess, whether patients are ready for discharge after a planned outpatient procedure.

目的:目前,关于推进和扩大鼻外科门诊手术的讨论十分热烈。关于如何划分门诊手术和住院手术的许多问题仍未得到充分澄清。尤其是鼻腔填塞材料的使用问题尚未得到充分讨论:材料和方法:考虑到当前的科学文献和风险因素,制定一份检查表,将鼻窦手术分为住院或门诊手术:结果和结论:在对文献进行综合评估并分析特定风险因素后,提出了一份应作为住院手术进行的鼻窦手术清单。我们提出了一份住院和门诊鼻窦手术清单,其中考虑了社会、医疗和手术因素以及鼻腔包装材料的使用。此外,我们还添加了一份核对表,用于评估患者是否已准备好在计划的门诊手术后出院。
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引用次数: 0
[Survey on the use of nasal tamponades in sinunasal surgery]. [关于在鼻窦手术中使用鼻腔填塞物的调查]。
IF 0.9 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-09-30 DOI: 10.1055/a-2351-1500
Rainer K Weber, Thomas Deitmer, Jan Löhler, Christoph Aletsee, Ingo Baumann, Christian Betz, Achim Beule, Robert Böscke, Andreas Dietz, Vanessa Harnischmacher, Frank Haubner, Werner Heppt, Anna Sophie Hoffmann, Thomas K Hoffmann, Werner Hosemann, Thomas Kühnel, Martin Laudien, Bernhard Olzowy, Kim-Victoria Seibert, Fabian Sommer, Thomas Verse, Susanne Wiegand, Tanja Hildenbrand

Objective: Currently, there is an intensive discussion about enhancing and expanding outpatient rhinosurgical procedures. Many questions about how to stratify into out- and inpatient procedures are still not sufficiently clarified. Particularly, the use of nasal packing materials is not adequately discussed.

Material and methods: We performed a Germany-wide survey among otorhinolaryngologists regarding the use of nasal packing materials in sinonasal surgery. Additionally, we asked for any complication in relation to nasal packing.

Results: In 85,6% nasal packing was used for septal and turbinate surgery at least occasionally, in 44,2% always. In sinus surgery these numbers are 94,1% and 49%, respectively. Non-resorbable nasal packing materials were predominantly used.Most frequent complications were bleeding with nasal packing in situ (> 50% of respondents) and posterior dislocation (24% of respondents), requiring emergency treatment. Death was listed in 5 patients. One patient suffered from permanent brain damage due to hypoxia.

Conclusions: Application of non-resorbable nasal packing materials with occlusion of the nasal cavity carry a substantial risk of complications, which necessitate emergency treatment, thus requiring inpatient care.

目的:目前,关于加强和扩大鼻外科门诊手术的讨论十分激烈。关于如何划分门诊手术和住院手术的许多问题仍未得到充分澄清。材料和方法:我们在全德范围内对耳鼻喉科医生进行了一项关于鼻窦手术中鼻腔填料使用情况的调查。此外,我们还询问了与鼻腔填料有关的任何并发症:85.6%的鼻中隔和鼻甲手术至少偶尔使用鼻腔填料,44.2%的鼻中隔和鼻甲手术经常使用鼻腔填料。在鼻窦手术中,这一比例分别为 94.1%和 49%。最常见的并发症是鼻腔填料原位出血(超过 50% 的受访者)和后脱位(24% 的受访者),需要紧急治疗。有 5 名患者死亡。一名患者因缺氧导致永久性脑损伤:结论:应用不可吸收的鼻腔填塞材料堵塞鼻腔有很大的并发症风险,必须进行紧急治疗,因此需要住院治疗。
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引用次数: 0
[Rare entity of a supraglottic laryngeal tumour in a lung transplant patient]. [肺移植患者罕见的声门上型喉肿瘤]。
IF 0.9 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-09-30 DOI: 10.1055/a-2410-1973
Martin Sorge, Alexandra Wald, Marie Erika Eva Liebetrau, Andreas Dietz, Susanne Wiegand, Matthaeus Stoehr
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引用次数: 0
[Ultrasound - part 5: closer look at sinus sonography]. [超声 - 第五部分:鼻窦超声造影近距离观察]。
IF 0.9 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-09-26 DOI: 10.1055/a-2251-0672
Charles Schmit, Verena Strasser, Helen Heppt, Veronika Innerhofer, Timo Gottfried, Benedikt Hofauer, Daniel Dejaco
{"title":"[Ultrasound - part 5: closer look at sinus sonography].","authors":"Charles Schmit, Verena Strasser, Helen Heppt, Veronika Innerhofer, Timo Gottfried, Benedikt Hofauer, Daniel Dejaco","doi":"10.1055/a-2251-0672","DOIUrl":"https://doi.org/10.1055/a-2251-0672","url":null,"abstract":"","PeriodicalId":17965,"journal":{"name":"Laryngo-rhino-otologie","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142349307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Nasal hemorrhage - risk factors and management in 707 outpatient and inpatient patients]. [鼻出血--707 名门诊和住院病人的风险因素和处理方法]。
IF 0.9 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-09-09 DOI: 10.1055/a-2406-5519
Nikita Breyer, Benjamin Mayer, Jörg Lindemann, Thomas Karl Hoffmann, Janina Hahn

Epistaxis is one of the most common emergencies in otorhinolaryngology. The spectrum ranges from mild, self-limiting cases to life-threatening hemorrhages. Depending on the severity and course of the condition, management can be either outpatient or involve inpatient monitoring, possibly with surgical treatment.A retrospective systematic evaluation was conducted on all outpatient and inpatient patient data diagnosed with epistaxis from January to December 2021. Epistaxis associated with tumors, trauma, and postoperative epistaxis were excluded.A total of 707 patients were included. Seasonally, the highest number of patients presented in January. Outpatient management was possible for 80.8% of the cases, while 19.2% required inpatient admission. Among the inpatients, 15.4% required surgical intervention. Within the entire study cohort, 61.1% of the patients were male. Among the inpatients who underwent surgical treatment, the proportion of male patients was even higher (81.0%). The majority (73.1%) of the inpatients were on at least one anticoagulant medication. Advanced age (p=0.044) and the presence of posterior epistaxis (p<0.001) were significantly associated with the need for inpatient treatment. No children required inpatient care.Epistaxis is a common condition in otorhinolaryngology, predominantly affecting older male patients and those on anticoagulant therapy in severe cases within the studied cohort. Surgical intervention under general anesthesia was infrequently necessary for the treatment of epistaxis in the overall study population (3%).

鼻衄是耳鼻喉科最常见的急症之一。其范围从轻微的自限性病例到危及生命的大出血不等。根据病情的严重程度和病程,治疗方式可以是门诊治疗,也可以是住院观察,可能还需要手术治疗。共纳入 707 名患者。从季节上看,1 月份的患者人数最多。80.8%的病例可以在门诊治疗,19.2%的病例需要住院治疗。在住院患者中,15.4%需要手术治疗。在整个研究队列中,61.1% 的患者为男性。在接受手术治疗的住院患者中,男性患者的比例更高(81.0%)。大多数住院患者(73.1%)至少服用一种抗凝药物。高龄(p=0.044)和后鼻衄(p
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引用次数: 0
期刊
Laryngo-rhino-otologie
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