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[Treatment of bilharziasis in Madagascar. Use of oltipraz in mass campaign against S. mansoni and S. haematobium]. 马达加斯加血吸虫病的治疗。在群众性运动中使用oltipraz来对抗S. mansoni和S. haematobium。
Pub Date : 1982-12-11
J Moyroud, J Breuil, P Coulanges, G Charmot
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引用次数: 0
[Ventriculo-coronarography in the diabetic. Study of 238 patients]. 糖尿病患者的脑室冠状造影。238例患者的研究]。
Pub Date : 1982-12-11
C Schurtz, J P Lesbre, G Jarry, P Fardellone, A Kalisa, F Funck, J Simony
{"title":"[Ventriculo-coronarography in the diabetic. Study of 238 patients].","authors":"C Schurtz, J P Lesbre, G Jarry, P Fardellone, A Kalisa, F Funck, J Simony","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":17974,"journal":{"name":"La Nouvelle presse medicale","volume":"11 50","pages":"3731"},"PeriodicalIF":0.0,"publicationDate":"1982-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18185480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Association of hyperthyroidism and mitral valve prolapse]. [甲亢与二尖瓣脱垂的关系]。
Pub Date : 1982-12-11
S Drui, C M Brandt, J F Blickle, J L Fincker
{"title":"[Association of hyperthyroidism and mitral valve prolapse].","authors":"S Drui, C M Brandt, J F Blickle, J L Fincker","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":17974,"journal":{"name":"La Nouvelle presse medicale","volume":"11 50","pages":"3728"},"PeriodicalIF":0.0,"publicationDate":"1982-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17949529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Place of the scanner in the diagnosis of renal tumors]. 【扫描仪在肾脏肿瘤诊断中的地位】。
Pub Date : 1982-12-11
J P Fendler, C Felsenheld, Y Lopez, D Hillion, A Bruet
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引用次数: 0
[Cardiovascular effects of prostacyclin]. 前列环素对心血管的影响。
Pub Date : 1982-12-11
M Chaignon, G Guelpa, M Lucsko, J Guédon

Numerous studies have recently been devoted to the effects of prostaglandins on blood vessels. Prostacyclin (PGI2) produces relaxation of vascular smooth muscles, thereby contributing, with other vasoactive substances, to the regulation of general and local haemodynamics. Moreover, it would appear that the effects of some risk factors in atherosclerosis are mediated, at least partly, by changes in prostaglandin production. The potent vasodilator action of prostacyclin has been confirmed in man and has been investigated in some pathological conditions, such as lower limb arteriopathy, malignant arterial hypertension and coronary artery disease. The vascular effects of many therapeutic drugs are now known to be associated with their action on the biosynthesis of prostaglandins. Further studies are required to determine the role of prostaglandins, especially prostacyclin, in the pathophysiology, prevention and treatment of vascular diseases.

最近有许多研究致力于前列腺素对血管的影响。前列环素(PGI2)使血管平滑肌松弛,从而与其他血管活性物质一起调节全身和局部血流动力学。此外,似乎动脉粥样硬化中某些危险因素的影响至少部分是由前列腺素生成的变化介导的。前列环素的强效血管扩张作用已在人体中得到证实,并在一些病理情况下,如下肢动脉病变、恶性动脉高血压和冠状动脉疾病中进行了研究。现在已知许多治疗药物的血管效应与它们对前列腺素生物合成的作用有关。前列腺素尤其是前列环素在血管疾病的病理生理、预防和治疗中的作用有待进一步研究。
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引用次数: 0
[Favorable effect of the sulfamethoxazole-trimethoprim combination on the evolution of congenital bullous epidermolysis of the dystrophic form]. [磺胺甲恶唑-甲氧苄啶联合治疗对营养不良型先天性大疱性表皮松解症的有利影响]。
Pub Date : 1982-12-11
B Beyne
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引用次数: 0
[Is it preferable to prescribe 1 or 2 daily doses of sodium valproate?]. [每日服用1次或2次丙戊酸钠比较好吗?]
Pub Date : 1982-12-11
P Loiseau, R H Levy, M Guyot, P L Morselli, A Brachet-Liermain

Enteric-coated tablets containing 1 500 mg of sodium valproate (VPA) were administered in a randomized fashion either once or three times a day for 7 days to 6 healthy adult volunteers. Plasma total VPA levels and unbound fractions of the drug were determined 2-hourly on the last day of each treatment. Peak plasma concentrations were higher, and minimum plasma concentrations lower with one single dose than with three doses. In subjects who received three doses, the concentration curves tended to plateau, with higher AUC values. However, none of the differences observed reached statistical significance. The clinical implications of these pharmacokinetic data are discussed.

对6名健康成年志愿者随机给予含有1 500 mg丙戊酸钠(VPA)的肠溶片,每天1次或3次,持续7天。在每次治疗的最后一天2小时测定血浆总VPA水平和药物的未结合部分。单次给药的峰值血浆浓度高于三次给药的最低血浆浓度。在接受三次剂量的受试者中,浓度曲线趋于平稳,AUC值较高。然而,观察到的差异均未达到统计学意义。这些药代动力学数据的临床意义进行了讨论。
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引用次数: 0
[Malignant myelofibrosis. Evolution toward acute lymphoblastic leukemia]. (恶性骨髓纤维化。向急性淋巴细胞白血病的进化]。
Pub Date : 1982-12-11
C Fantesini, S Prandi, I Iori, C Salvarani
{"title":"[Malignant myelofibrosis. Evolution toward acute lymphoblastic leukemia].","authors":"C Fantesini,&nbsp;S Prandi,&nbsp;I Iori,&nbsp;C Salvarani","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":17974,"journal":{"name":"La Nouvelle presse medicale","volume":"11 50","pages":"3729"},"PeriodicalIF":0.0,"publicationDate":"1982-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18014515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Angioimmunoblastic lymphadenopathy with cutaneous leukocytoclastic vasculitis. 2 cases]. 血管免疫母细胞性淋巴结病伴皮肤白细胞破坏性血管炎。2例)。
Pub Date : 1982-12-11
P Arlet, M Laroche, G Delsol, G Seigneuric, M Duffaut, Y Le Tallec

In two patients with similar symptoms (fever, very poor general condition, skin rash, pulmonary involvement, multiple lymphadenopathy and phlebitis) pathological examination disclosed angioimmunoblastic lesions in lymph nodes and leucocytoblastic vascularities in the skin. While all cases published so far were exceptional, the clinical and pathophysiological findings were strikingly similar in these two cases, and the possibility of a special nosological entity is considered. If relapses are to be avoided, both patients will require continuous high dosage corticosteroid therapy, which aggravates the long-term prognosis.

2例患者症状相似(发热、全身状况极差、皮疹、肺部受累、多发性淋巴结病和静脉炎),病理检查发现淋巴结血管免疫病变和皮肤白细胞增生血管。虽然到目前为止发表的所有病例都是例外,但这两个病例的临床和病理生理结果惊人地相似,并且考虑了特殊疾病实体的可能性。如果要避免复发,两名患者都需要持续的高剂量皮质类固醇治疗,这会加重长期预后。
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引用次数: 0
[Colonic villous tumor and modification of taste]. [结肠绒毛瘤与味觉改变]。
Pub Date : 1982-12-11
B Maroy
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引用次数: 0
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La Nouvelle presse medicale
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