Pub Date : 2023-10-30DOI: 10.1088/1555-6611/ad04c8
B S Abdullaeva, T Alawsi, A Alawadi, A Alsalamy
Abstract The optomechanically induced grating (OMIG) in a nanocavity using a bilayer graphene system as the intracavity medium has been proposed. We investigate the effects of different parameters on the Fraunhofer diffraction pattern of the incident probe light. Here, one mirror of the nanocavity is considered coherently driven by the standing wave coupling and probe fields, whereas the second mirror has mechanical oscillation due to the radiation pressure. We consider interaction of bilayer graphene with the optomechanical cavity and show that OMIG can be obtained corresponding to output probe field frequency. Moreover, we find that under specific parametric conditions, most of the probe energy can transfer to the higher orders of the diffraction and only a small portion remains in the zero order.
{"title":"Optomechanically induced grating in a graphene based nanocavity","authors":"B S Abdullaeva, T Alawsi, A Alawadi, A Alsalamy","doi":"10.1088/1555-6611/ad04c8","DOIUrl":"https://doi.org/10.1088/1555-6611/ad04c8","url":null,"abstract":"Abstract The optomechanically induced grating (OMIG) in a nanocavity using a bilayer graphene system as the intracavity medium has been proposed. We investigate the effects of different parameters on the Fraunhofer diffraction pattern of the incident probe light. Here, one mirror of the nanocavity is considered coherently driven by the standing wave coupling and probe fields, whereas the second mirror has mechanical oscillation due to the radiation pressure. We consider interaction of bilayer graphene with the optomechanical cavity and show that OMIG can be obtained corresponding to output probe field frequency. Moreover, we find that under specific parametric conditions, most of the probe energy can transfer to the higher orders of the diffraction and only a small portion remains in the zero order.","PeriodicalId":17976,"journal":{"name":"Laser Physics","volume":"83 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136102319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Optical fiber vector solitons have potential applications in the field of high-capacity optical fiber communications and have been widely explored in recent years. Here, we theoretically modulate dual-wavelength optical fiber vector solitons in an optical fiber system at a wavelength regime of 1 μ m while considering the influence of group velocity dispersion. When the input dual-wavelength optical fiber vector solitons have the same two central wavelengths of 1057 nm and 1063 nm in orthogonal directions, the output modulated optical fiber vector solitons’ pulse shapes and optical spectra will maintain their peak intensities upon the change of the projection angle. When the two orthogonal central wavelengths of the input dual-wavelength optical fiber vector solitons are slightly different (1056 nm and 1062 nm in one polarization direction, 1058 nm and 1064 nm in the other direction), dual-peak pulse shapes appear and are accompanied by different wavelength peak intensities when the propagation distance increases. Our simulation results examine the out-cavity modulation of dual-wavelength optical fiber vector solitons and can be expanded to multi-wavelength optical fiber vector solitons’ modulation.
{"title":"Modulating dual-wavelength optical fiber vector solitons","authors":"Guangyu Xu, Yangyang Peng, Yongqiang Tang, Keyun Zhang, Meisong Liao, Yongzheng Fang, Yan Zhou","doi":"10.1088/1555-6611/ad04cc","DOIUrl":"https://doi.org/10.1088/1555-6611/ad04cc","url":null,"abstract":"Abstract Optical fiber vector solitons have potential applications in the field of high-capacity optical fiber communications and have been widely explored in recent years. Here, we theoretically modulate dual-wavelength optical fiber vector solitons in an optical fiber system at a wavelength regime of 1 μ m while considering the influence of group velocity dispersion. When the input dual-wavelength optical fiber vector solitons have the same two central wavelengths of 1057 nm and 1063 nm in orthogonal directions, the output modulated optical fiber vector solitons’ pulse shapes and optical spectra will maintain their peak intensities upon the change of the projection angle. When the two orthogonal central wavelengths of the input dual-wavelength optical fiber vector solitons are slightly different (1056 nm and 1062 nm in one polarization direction, 1058 nm and 1064 nm in the other direction), dual-peak pulse shapes appear and are accompanied by different wavelength peak intensities when the propagation distance increases. Our simulation results examine the out-cavity modulation of dual-wavelength optical fiber vector solitons and can be expanded to multi-wavelength optical fiber vector solitons’ modulation.","PeriodicalId":17976,"journal":{"name":"Laser Physics","volume":"253 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136102633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-30DOI: 10.1088/1555-6611/ad04c7
Mohammad Karami, Zahra Heydarinasab, Farrokh Sarreshtedari
Abstract Analytical modeling of the sub-Doppler dichroic atomic vapor laser lock error signal shows that the slope of this error signal could be of interest for the identification of transitions in alkali atom hyperfine spectroscopy. Among four D1 line transitions of alkali atoms, the slope sign of the sub-Doppler error signal is different only for the case when the Landé g -factor is negative for both the ground and excited states. The analytical model used, which includes all sublevel transitions, shows very good agreement with the experimental spectroscopy results. The use of this technique allows us to accurately characterize hyperfine transitions in alkali atoms without the need for advanced spectroscopic tools.
{"title":"Sub-Doppler dichroism as a useful tool in alkali atom hyperfine spectroscopy","authors":"Mohammad Karami, Zahra Heydarinasab, Farrokh Sarreshtedari","doi":"10.1088/1555-6611/ad04c7","DOIUrl":"https://doi.org/10.1088/1555-6611/ad04c7","url":null,"abstract":"Abstract Analytical modeling of the sub-Doppler dichroic atomic vapor laser lock error signal shows that the slope of this error signal could be of interest for the identification of transitions in alkali atom hyperfine spectroscopy. Among four D1 line transitions of alkali atoms, the slope sign of the sub-Doppler error signal is different only for the case when the Landé g -factor is negative for both the ground and excited states. The analytical model used, which includes all sublevel transitions, shows very good agreement with the experimental spectroscopy results. The use of this technique allows us to accurately characterize hyperfine transitions in alkali atoms without the need for advanced spectroscopic tools.","PeriodicalId":17976,"journal":{"name":"Laser Physics","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136067809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-25DOI: 10.1088/1555-6611/ad00a7
M Alquraishi, V E Lembessis, A Lyras, O M Aldossary
Abstract Truncated optical Bessel (TOB) beams are an orthonormal set of optical vortex beams that possess orbital angular momentum (OAM). It is characterized by a significant longitudinal electric field component at the sub-wavelength scales. The photons of a circularly polarized TOB beam also carry spin angular momentum (SAM) and can interact with a two-level atom, in the far-off resonance regime, giving rise to an optical dipole potential energy that involves a spin–orbit term that stems from the inclusion of the longitudinal field component. When a two-level atom is simultaneously irradiated by two TOB beams, the optical dipole potential energy, in some special cases, is entirely dependent on the OAM–SAM coupling. We explore the cold-atom trapping options enabled by the use of TOB beams, either single ones or combinations thereof. We put emphasis on case in which the OAM–SAM coupling is the dominant contribution. The similarities and differences between the results obtained for the TOB beams and those for the Laguerre–Gaussian beams are also discussed.
{"title":"Optical dipole potential energy of a two-level atom interacting with a tightly focused truncated optical Bessel beam","authors":"M Alquraishi, V E Lembessis, A Lyras, O M Aldossary","doi":"10.1088/1555-6611/ad00a7","DOIUrl":"https://doi.org/10.1088/1555-6611/ad00a7","url":null,"abstract":"Abstract Truncated optical Bessel (TOB) beams are an orthonormal set of optical vortex beams that possess orbital angular momentum (OAM). It is characterized by a significant longitudinal electric field component at the sub-wavelength scales. The photons of a circularly polarized TOB beam also carry spin angular momentum (SAM) and can interact with a two-level atom, in the far-off resonance regime, giving rise to an optical dipole potential energy that involves a spin–orbit term that stems from the inclusion of the longitudinal field component. When a two-level atom is simultaneously irradiated by two TOB beams, the optical dipole potential energy, in some special cases, is entirely dependent on the OAM–SAM coupling. We explore the cold-atom trapping options enabled by the use of TOB beams, either single ones or combinations thereof. We put emphasis on case in which the OAM–SAM coupling is the dominant contribution. The similarities and differences between the results obtained for the TOB beams and those for the Laguerre–Gaussian beams are also discussed.","PeriodicalId":17976,"journal":{"name":"Laser Physics","volume":"8 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135113426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract We demonstrate a high power compact continuous-wave diode side-pumped Tm,Ho:YAG all solid-state laser at room temperature. A high dopant concentration ratio of Tm,Ho:YAG (3 at.% Tm 3+ , 0.1 at.% Ho 3+ ) crystal rod with laser diode (LD) side-pumped architecture is employed as a laser head. With a single laser head in a plane-parallel short cavity, a maximum 57 W output power is obtained at a temperature of 19 °C, corresponding to an optical-to-optical efficiency of 10.6% and a slope efficiency of 16.6%. To the best of our knowledge, this is the highest output power of LD-pumped Tm,Ho co-doped laser operating at room temperature. This laser system also exhibits excellent power stability in 90 min, making it widely applicable in various fields.
在室温下，研究了高功率紧凑连续波二极管侧泵浦Tm,Ho:YAG全固态激光器。Tm,Ho:YAG (3 at)的高掺杂浓度比。% Tm 3+， 0.1 at。采用激光二极管(LD)侧泵浦结构的% Ho 3+晶体棒作为激光头。单激光头在平面平行短腔中，在温度为19℃的条件下，最大输出功率为57 W，光对光效率为10.6%，斜率效率为16.6%。据我们所知，这是室温下工作的ld泵浦Tm,Ho共掺杂激光器的最高输出功率。该激光系统还具有优异的90分钟功率稳定性，广泛应用于各个领域。
{"title":"A compact high power diode side-pumped 2.09 μm Tm,Ho:YAG laser","authors":"Jian-Hong Wu, Shi-Feng Du, Hai-Long Wang, Yun Gao, Yong Bo, Da-Fu Cui, Qin-Jun Peng","doi":"10.1088/1555-6611/ad00a9","DOIUrl":"https://doi.org/10.1088/1555-6611/ad00a9","url":null,"abstract":"Abstract We demonstrate a high power compact continuous-wave diode side-pumped Tm,Ho:YAG all solid-state laser at room temperature. A high dopant concentration ratio of Tm,Ho:YAG (3 at.% Tm 3+ , 0.1 at.% Ho 3+ ) crystal rod with laser diode (LD) side-pumped architecture is employed as a laser head. With a single laser head in a plane-parallel short cavity, a maximum 57 W output power is obtained at a temperature of 19 °C, corresponding to an optical-to-optical efficiency of 10.6% and a slope efficiency of 16.6%. To the best of our knowledge, this is the highest output power of LD-pumped Tm,Ho co-doped laser operating at room temperature. This laser system also exhibits excellent power stability in 90 min, making it widely applicable in various fields.","PeriodicalId":17976,"journal":{"name":"Laser Physics","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135729937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-16DOI: 10.1088/1555-6611/acfb75
Aleksandr N Bugay, Vyacheslav A Khalyapin
Abstract An analytical estimation of the parameters of light bullets formed in the region of anomalous group dispersion in dielectrics under conditions of tunneling photoionization has been carried out. A system of ordinary differential equations for the parameters of a laser pulse is obtained by the method of moments. A new analytical approximation is proposed for calculating the contribution of tunneling ionization. With the help of Lyapunov’s stability theory, a quasi-stationary solution of this system and conditions for a quasi-stable propagation regime are found.
{"title":"Analysis of the stability region of light bullets propagating in the tunnel ionization mode in dielectric","authors":"Aleksandr N Bugay, Vyacheslav A Khalyapin","doi":"10.1088/1555-6611/acfb75","DOIUrl":"https://doi.org/10.1088/1555-6611/acfb75","url":null,"abstract":"Abstract An analytical estimation of the parameters of light bullets formed in the region of anomalous group dispersion in dielectrics under conditions of tunneling photoionization has been carried out. A system of ordinary differential equations for the parameters of a laser pulse is obtained by the method of moments. A new analytical approximation is proposed for calculating the contribution of tunneling ionization. With the help of Lyapunov’s stability theory, a quasi-stationary solution of this system and conditions for a quasi-stable propagation regime are found.","PeriodicalId":17976,"journal":{"name":"Laser Physics","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136115216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-16DOI: 10.1088/1555-6611/acfb78
Junwen Bai, Xinhua Fu
Abstract A simultaneous continuous-wave (CW) dual-wavelength Pr:LiGdF 4 laser using a single birefringent filter (BF) plate under excitation with a frequency doubled optically pumped semiconductor laser (2 ω -OPSL) was experimentally demonstrated. We calculate the wavelength-dependent loss property of the BF. By adjusting the BF plate, the spectral intensity ratio of the generated wavelengths can be maintained to be 1:1. A simultaneous CW dual-wavelength Pr:LiGdF 4 laser at 604 and 523 nm is experimentally realized. For a pump power of 7.2 W, red and green dual-wavelength laser radiation at 604 and 523 nm and 1.25 W of output power using a 4% output coupler could be generated. A slope efficiency of 19.8% with respect to the absorbed pump power and optical-to-optical efficiency of 17.4% for the highest-incident pump power were obtained. To our knowledge, this is the first study that has realized a dual-wavelength in Pr:LiGdF 4 laser.
{"title":"Red and green dual-wavelength Pr:LiGdF<sub>4</sub> laser with a single birefringent filter","authors":"Junwen Bai, Xinhua Fu","doi":"10.1088/1555-6611/acfb78","DOIUrl":"https://doi.org/10.1088/1555-6611/acfb78","url":null,"abstract":"Abstract A simultaneous continuous-wave (CW) dual-wavelength Pr:LiGdF 4 laser using a single birefringent filter (BF) plate under excitation with a frequency doubled optically pumped semiconductor laser (2 ω -OPSL) was experimentally demonstrated. We calculate the wavelength-dependent loss property of the BF. By adjusting the BF plate, the spectral intensity ratio of the generated wavelengths can be maintained to be 1:1. A simultaneous CW dual-wavelength Pr:LiGdF 4 laser at 604 and 523 nm is experimentally realized. For a pump power of 7.2 W, red and green dual-wavelength laser radiation at 604 and 523 nm and 1.25 W of output power using a 4% output coupler could be generated. A slope efficiency of 19.8% with respect to the absorbed pump power and optical-to-optical efficiency of 17.4% for the highest-incident pump power were obtained. To our knowledge, this is the first study that has realized a dual-wavelength in Pr:LiGdF 4 laser.","PeriodicalId":17976,"journal":{"name":"Laser Physics","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136113768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-16DOI: 10.1088/1555-6611/ad00a8
S A Anuar, M F A Rahman, A M M Nasir, A A Latiff, M F M Rusdi, S W Harun
Abstract A self-induced Q-switched erbium-doped fiber laser operating at 1563 nm was achieved by integrating a passive modulator based on tantalum aluminum carbide (Ta 2 AlC) MAX phase film embedded into polyynyl alcohol. The modulator, serving as a saturable absorber (SA), established a modulation depth of 9% and a saturation intensity of 0.3 MW cm −2 . Upon integration of the film SA, a stable Q-switched fiber laser was obtained, generating pulses with a minimum width of 7.6 µ s at a repetition rate of 45.1 kHz, within a pump power range of 24.9–59.7 mW. The corresponding maximum average output power, maximum pulse energy, and highest peak power were determined at 1.6 mW, 36.2 nJ, and 4.7 mW, respectively. The RF fundamental spectrum exhibited a good signal-to-noise ratio of 61 dB, indicating excellent pulse signal quality. This demonstration of Ta 2 AlC MAX phase film Q-switched laser may open promising possibilities for scientific applications such as material processing.
{"title":"Self-induced Q-switched fiber laser using tantalum aluminum carbide as a passive modulator","authors":"S A Anuar, M F A Rahman, A M M Nasir, A A Latiff, M F M Rusdi, S W Harun","doi":"10.1088/1555-6611/ad00a8","DOIUrl":"https://doi.org/10.1088/1555-6611/ad00a8","url":null,"abstract":"Abstract A self-induced Q-switched erbium-doped fiber laser operating at 1563 nm was achieved by integrating a passive modulator based on tantalum aluminum carbide (Ta 2 AlC) MAX phase film embedded into polyynyl alcohol. The modulator, serving as a saturable absorber (SA), established a modulation depth of 9% and a saturation intensity of 0.3 MW cm −2 . Upon integration of the film SA, a stable Q-switched fiber laser was obtained, generating pulses with a minimum width of 7.6 µ s at a repetition rate of 45.1 kHz, within a pump power range of 24.9–59.7 mW. The corresponding maximum average output power, maximum pulse energy, and highest peak power were determined at 1.6 mW, 36.2 nJ, and 4.7 mW, respectively. The RF fundamental spectrum exhibited a good signal-to-noise ratio of 61 dB, indicating excellent pulse signal quality. This demonstration of Ta 2 AlC MAX phase film Q-switched laser may open promising possibilities for scientific applications such as material processing.","PeriodicalId":17976,"journal":{"name":"Laser Physics","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136114380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-10DOI: 10.1088/1555-6611/acf6ba
Great Chayran, Venkatesan Jambunathan, Martin Smrz, Tomas Mocek
Abstract We demonstrated a 577 nm yellow laser source with a proper combination of Raman medium and frequency doubling medium, pumped externally. Cryogenic Yb:YAG oscillator acts as an external pump source, and it generates 1.2 mJ energy at 1 KHz emitting around 1029 nm. Using a Raman resonator with Ba(NO 3 ) 2 as Raman medium, stimulated Raman scattering around 1153.4 was generated. Finally, 577 nm yellow laser was generated using the frequency-doubling medium LBO. A maximum average output power of 65 mW with a pulse duration of 18 ns at 1 KHz was achieved.
{"title":"Externally pumped yellow laser source emitting at 577 nm","authors":"Great Chayran, Venkatesan Jambunathan, Martin Smrz, Tomas Mocek","doi":"10.1088/1555-6611/acf6ba","DOIUrl":"https://doi.org/10.1088/1555-6611/acf6ba","url":null,"abstract":"Abstract We demonstrated a 577 nm yellow laser source with a proper combination of Raman medium and frequency doubling medium, pumped externally. Cryogenic Yb:YAG oscillator acts as an external pump source, and it generates 1.2 mJ energy at 1 KHz emitting around 1029 nm. Using a Raman resonator with Ba(NO 3 ) 2 as Raman medium, stimulated Raman scattering around 1153.4 was generated. Finally, 577 nm yellow laser was generated using the frequency-doubling medium LBO. A maximum average output power of 65 mW with a pulse duration of 18 ns at 1 KHz was achieved.","PeriodicalId":17976,"journal":{"name":"Laser Physics","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136294836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-06DOI: 10.1088/1555-6611/acfd9b
Rickson Souza Ribeiro, Juliana Alves Rodrigues, Márcia dos Santos Soares, Andre Luiz Mencalha, Adenilson de Souza da Fonseca
Abstract Low-power blue light-emitting diode (LED) and red laser have been used for therapeutic proposals based on photobiomodulation (PBM). This effect is trigged after absorption of radiation by photoacceptors, which lead to molecular, cellular and systemic responses. Cryptochromes are involved in circadian cycle control, and associated with development and progression of tumors. Despite such proteins are able to absorb violet-blue lights, there are few data on their participation in PBM. Thus, this work aims to evaluate the effects of radiations emitted by low-power blue LED (470 nm) and red laser (658 nm) on mRNA levels from cryptochromes genes as well as those from involved in their regulation in human breast cancer cells. The MCF-7 and MDA-MB-231 cells were exposed to low-power blue LED (470 nm, 640 J cm −2 ) and red laser (660 nm, 9 J cm −2 ), and relative mRNA levels from CRY1, CRY2, PER2, BMAL1 and CLOCK genes were evaluated by reverse transcription-quantitative polymerase chain reaction. The results suggested that exposure to low-power blue LED and red laser do not alter the mRNA levels from cryptochromes genes, and those involved in their regulation, in MCF-7 and MDA-MB-231 human breast cancer cells.
{"title":"Low-power red laser and blue LED on circadian gene mRNA levels in human breast cancer cells","authors":"Rickson Souza Ribeiro, Juliana Alves Rodrigues, Márcia dos Santos Soares, Andre Luiz Mencalha, Adenilson de Souza da Fonseca","doi":"10.1088/1555-6611/acfd9b","DOIUrl":"https://doi.org/10.1088/1555-6611/acfd9b","url":null,"abstract":"Abstract Low-power blue light-emitting diode (LED) and red laser have been used for therapeutic proposals based on photobiomodulation (PBM). This effect is trigged after absorption of radiation by photoacceptors, which lead to molecular, cellular and systemic responses. Cryptochromes are involved in circadian cycle control, and associated with development and progression of tumors. Despite such proteins are able to absorb violet-blue lights, there are few data on their participation in PBM. Thus, this work aims to evaluate the effects of radiations emitted by low-power blue LED (470 nm) and red laser (658 nm) on mRNA levels from cryptochromes genes as well as those from involved in their regulation in human breast cancer cells. The MCF-7 and MDA-MB-231 cells were exposed to low-power blue LED (470 nm, 640 J cm −2 ) and red laser (660 nm, 9 J cm −2 ), and relative mRNA levels from CRY1, CRY2, PER2, BMAL1 and CLOCK genes were evaluated by reverse transcription-quantitative polymerase chain reaction. The results suggested that exposure to low-power blue LED and red laser do not alter the mRNA levels from cryptochromes genes, and those involved in their regulation, in MCF-7 and MDA-MB-231 human breast cancer cells.","PeriodicalId":17976,"journal":{"name":"Laser Physics","volume":"299 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135350464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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