LUTS: Lower Urinary Tract Symptoms最新文献_第5页

Serum anandamide and lipids associated with linoleic acid can distinguish interstitial cystitis/bladder pain syndrome from overactive bladder: An exploratory study 血清anandamide和与亚油酸相关的脂质可以区分间质性膀胱炎/膀胱疼痛综合征和膀胱过度活动：一项探索性研究。

IF 1.3 4区医学 Q3 UROLOGY & NEPHROLOGY

LUTS: Lower Urinary Tract Symptoms

Pub Date : 2023-09-08 DOI: 10.1111/luts.12501

Kazumasa Torimoto, Tomohiro Ueda, Daisuke Gotoh, Kuniyuki Kano, Makito Miyake, Yasushi Nakai, Shunta Hori, Yosuke Morizawa, Kenta Onishi, Takuto Shimizu, Mitsuru Tomizawa, Junken Aoki, Kiyohide Fujimoto

Objectives

Diagnosing interstitial cystitis/bladder pain syndrome presents a major challenge because it relies on subjective symptoms and empirical cystoscopic findings. A practical biomarker should discriminate diseases that cause increased urinary frequency, particularly overactive bladder. Therefore, we aimed to identify blood biomarkers that can discriminate between interstitial cystitis/bladder pain syndrome and overactive bladder.

Methods

We enrolled patients with Hunner-type interstitial cystitis (n = 20), bladder pain syndrome (n = 20), and overactive bladder (n = 20) and without lower urinary tract symptoms (controls, n = 15) at Ueda Clinic and Nara Medical University Hospital from February 2020 to August 2021. The degree of interstitial cystitis/bladder pain syndrome symptoms was evaluated using the interstitial cystitis symptom and problem indices. Metabolomics analysis was performed on 323 serum metabolites using liquid chromatography time-of-flight mass spectrometry.

Results

In the Hunner-type interstitial cystitis or bladder pain syndrome group, we observed smaller relative areas, including anandamide, acylcarnitine (18:2), linoleoyl ethanolamide, and arachidonic acid, compared to those in the overactive bladder or control group. Notably, the differences in the relative areas of anandamide were statistically significant (median: 3.950e-005 and 4.150e-005 vs. 8.300e-005 and 9.800e-005), with an area under the curve of 0.9321, demonstrating its ability to discriminate interstitial cystitis/bladder pain syndrome.

Conclusions

Serum anandamide may be a feasible diagnostic biomarker for interstitial cystitis/bladder pain syndrome. Reduced serum anandamide levels may be associated with pain and inflammation initiation, reflecting the pathology of interstitial cystitis/bladder pain syndrome. Furthermore, our findings suggest that abnormal linoleic acid metabolism may be involved in the pathogenesis of interstitial cystitis/bladder pain syndrome.

目的：诊断间质性膀胱炎/膀胱疼痛综合征是一项重大挑战，因为它依赖于主观症状和经验膀胱镜检查结果。一个实用的生物标志物应该区分导致尿频增加的疾病，尤其是膀胱过度活动。因此，我们旨在确定可以区分间质性膀胱炎/膀胱疼痛综合征和膀胱过度活动的血液生物标志物。方法：我们纳入了Hunner型间质性膀胱炎（n = 20），膀胱疼痛综合征（n = 20）和膀胱过度活动（n = 20）并且没有下尿路症状（对照组，n = 15） 2020年2月至2021年8月在上田诊所和奈良医科大学医院。间质性膀胱炎/膀胱疼痛综合征症状的程度使用间质性胱炎症状和问题指数进行评估。使用液相色谱-飞行时间质谱法对323种血清代谢物进行代谢组学分析。结果：在Hunner型间质性膀胱炎或膀胱疼痛综合征组中，与膀胱过度活动组或对照组相比，我们观察到较小的相对面积，包括anandamide、酰基肉碱（18:2）、亚麻酰乙醇酰胺和花生四烯酸。值得注意的是，阿那达明相对面积的差异具有统计学意义（中位数：3.950e-005和4.150e-005与8.300e-005和9.800e-005），曲线下面积为0.9321，表明其能够区分间质性膀胱炎/膀胱疼痛综合征。结论：血清阿那达明可能是间质性膀胱炎/膀胱疼痛综合征的一种可行的诊断生物标志物。血清anandamide水平降低可能与疼痛和炎症开始有关，反映了间质性膀胱炎/膀胱疼痛综合征的病理学。此外，我们的研究结果表明，亚油酸代谢异常可能参与间质性膀胱炎/膀胱疼痛综合征的发病机制。

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引用次数: 0

The expression and distribution of TACAN in human and rat bladders TACAN在人和大鼠膀胱中的表达和分布。

IF 1.3 4区医学 Q3 UROLOGY & NEPHROLOGY

LUTS: Lower Urinary Tract Symptoms

Pub Date : 2023-08-31 DOI: 10.1111/luts.12500

Qudong Lu, Qian Liu, Shiwei Chen, Jiaolian Wang, Yongjie Chen, Bishao Sun, Zhenxing Yang, Huan Feng, Shanhong Yi, Wei Chen, Jingzhen Zhu

Objectives

A lot of ion channels participate in the regulation of bladder function. TACAN, a new mechanosensitive ion channel, was first discovered in 2020. TACAN has been found to be expressed in many tissues, such as the dorsal root ganglia (DRG) and adipose tissue. However, it is unclear whether or not TACAN is expressed in the bladder. In this work, we decided to study the expression and distribution of TACAN in human and rat bladders. Meanwhile, the expression of TACAN in the rat model of interstitial cystitis/bladder pain syndrome (IC/BPS) was studied.

Methods

Human bladder tissues were obtained from female patients. Cyclophosphamide (CYP) was used to build the rat model of IC/BPS. Real-time polymerase chain reaction, agarose gel electrophoresis, and western blotting were used to assess the expression of TACAN in human and rat bladders. Immunohistochemistry and immunofluorescence were used to observe the distribution of TACAN in human and rat bladders. Hematoxylin-eosin stain, withdrawal threshold, and micturition interval were used to evaluate animal models.

Results

The results of agarose gel electrophoresis and western blotting suggested that TACAN was expressed in human and rat bladders. Immunohistochemical results suggested that TACAN showed positive immunoreaction in the urothelial and detrusor layers. The immunofluorescence results indicated that TACAN was co-stained with UPKIII, α-SMA, and PGP9.5. The IC/BPS model was successfully established with CYP. The mRNA and protein expression of TACAN was upregulated in the CYP-induced rat model of IC/BPS.

Conclusions

TACAN was found in human and rat bladders. TACAN was mainly distributed in the urothelial and detrusor layers and bladder nerves. The expression of TACAN was upregulated in the CYP-induced rat model of IC/BPS. This new discovery will provide a theoretical basis for future research on the function of TACAN in the bladder and a potential therapeutic target for IC/BPS.

目的：许多离子通道参与膀胱功能的调节。TACAN是一种新的机械敏感离子通道，于2020年首次被发现。TACAN已被发现在许多组织中表达，如背根神经节（DRG）和脂肪组织。然而，尚不清楚TACAN是否在膀胱中表达。在这项工作中，我们决定研究TACAN在人和大鼠膀胱中的表达和分布。同时，研究TACAN在大鼠间质性膀胱炎/膀胱疼痛综合征（IC/BPS）模型中的表达。方法：从女性患者身上获取人膀胱组织。采用环磷酰胺（CYP）建立IC/BPS大鼠模型。采用实时聚合酶链反应、琼脂糖凝胶电泳和蛋白质印迹法评估TACAN在人和大鼠膀胱中的表达。采用免疫组织化学和免疫荧光方法观察TACAN在人和大鼠膀胱中的分布。苏木精-伊红染色、停药阈值和排尿间隔时间用于评估动物模型。结果：琼脂糖凝胶电泳和蛋白质印迹结果表明，TACAN在人和大鼠膀胱中均有表达。免疫组化结果表明，TACAN在尿路上皮和逼尿肌层呈阳性免疫反应。免疫荧光结果表明，TACAN与UPKIII、α-SMA和PGP9.5共染色。用CYP成功建立了IC/BPS模型。在CYP诱导的IC/BPS大鼠模型中，TACAN的mRNA和蛋白表达上调。结论：在人和大鼠膀胱中发现了TACAN。TACAN主要分布于尿路上皮层、逼尿肌层和膀胱神经。在CYP诱导的IC/BPS大鼠模型中，TACAN的表达上调。这一新发现将为未来研究TACAN在膀胱中的作用提供理论基础，并为IC/BPS提供潜在的治疗靶点。

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引用次数: 0

Efficacy of cognitive behavioral therapy using self-check sheet for patients with nocturia in real-world clinical practice 在现实世界的临床实践中，使用自我检查表对夜尿症患者进行认知行为治疗的疗效。

IF 1.3 4区医学 Q3 UROLOGY & NEPHROLOGY

LUTS: Lower Urinary Tract Symptoms

Pub Date : 2023-08-23 DOI: 10.1111/luts.12498

Yuki Kyoda, Koji Ichihara, Ippei Muranaka, Yasuyuki Sakai, Makoto Nakamura, Nobuo Shinkai, Nodoka Kozen, Wakako Yorozuya, Daichi Morooka, Kazutaka Maruo, Kimihito Tachikawa, Kosuke Shibamori, Seisuke Nofuji, Keiko Fujino, Shuichi Kato, Takashi Yoshida, Tetsuya Shindo, Takeshi Maehana, Kohei Hashimoto, Ko Kobayashi, Toshiaki Tanaka, Naoya Masumori

Objectives

We previously demonstrated the efficacy of cognitive behavioral therapy (CBT) using a self-check sheet for patients with nocturia in a randomized controlled study. Additionally, we investigated the efficacy of the intervention in real-world clinical practice.

Methods

Two hundred forty-three outpatients with complaint of nocturia who practiced CBT for 4 weeks using a self-check sheet were included in this trial, which took place from April 2021 to March 2022 in 20 institutions.

Results

Of the 243 patients, 215 who achieved 50% or more of the behavioral therapy tasks were included in the analysis. Their mean age ± SD was 77.1 ± 7.7. A significant decrease was observed in nighttime frequency at 4 weeks after CBT using self-check sheets (pre 3.3 and post 2.8, p < .001). Nighttime frequency was decreased one or more times and was defined as treatment success in 102 patients (47.4%). Pretreatment nighttime frequency in the treatment-success group was significantly higher than that of the failure group (3.5 ± 1.0 vs. 3.2 ± 1.0, p = .013). In multivariate logistic regression analysis, predictive factors of treatment success were pretreatment nocturnal frequency of four or more (odds ratio [OR] 1.82, 95% confidence interval [CI] 1.01–3.30; p = .046) and the absence of diabetes mellitus (OR 3.08, 95% CI 1.34–7.06; p = .008).

Conclusions

CBT using a self-check sheet requiring less time, less labor, less cost, and less medication is very beneficial for both patients and medical staff in real-world clinical practice.

目的：我们之前在一项随机对照研究中使用自我检查表证明了认知行为疗法（CBT）对夜尿症患者的疗效。此外，我们还调查了干预措施在现实世界临床实践中的疗效。方法：243例夜间尿尿的门诊患者进行CBT治疗4年这项试验于2021年4月至2022年3月在20家机构进行，为期数周，使用自我检查表。结果：在243名患者中，215名完成了50%或以上行为治疗任务的患者被纳入分析。他们的平均年龄 ± SD为77.1 ± 7.7观察到夜间频率在4 CBT后数周使用自检表（3.3前和2.8后，p 结论：CBT使用自检表，需要更少的时间、更少的劳动力、更少的成本和更少的药物，在现实世界的临床实践中对患者和医务人员都非常有益。

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引用次数: 0

Uroflowmetry parameters in healthy children between 5 and 15 years old 5-15岁健康儿童的尿流量测定参数岁

IF 1.3 4区医学 Q3 UROLOGY & NEPHROLOGY

LUTS: Lower Urinary Tract Symptoms

Pub Date : 2023-08-23 DOI: 10.1111/luts.12499

Yeşim Demirkıran Öztürk, Ahmet Taner Elmas, Yılmaz Tabel

Objectives

Uroflowmetry (UFM) is the first-line noninvasive screening test employed in the diagnosis of lower urinary tract dysfunction (LUTD). The purpose of this study was to determine normal UFM values in healthy Turkish children among our local population.

Methods

A total of 100 healthy girls and 62 healthy boys aged 5–15 years, who applied to İnönü University Turgut Özal Medical Center Pediatrics Polyclinic between February 2021 and January 2022, were included in the present study. The UFM parameters, including maximum flow rate (Qmax), average flow rate (Qavg), voided volume (VV), time to maximum flow, and voiding time, were measured using the Inoflow Smart System UFM Device and the resulting urine flow curve was recorded. The children were compared in terms of the UFM parameters based on their gender and age groups (5–10 years and 11–15 years).

Results

The mean Qmax value in healthy female children aged 5–15 years (21.8 ± 8.6 mL/s) was significantly higher than in male children (17.98 ± 6.1 mL/s) (p = .003). VV, Qmax, and Qavg values of the children in the 11–15 age group were significantly higher than those in the age group of 5–10 years (p > .05 for each). VV, Qmax, and Qavg values were directly proportional to age (p = .0001, for each).

Conclusions

We believe that this study adds to the limited knowledge base regarding normal flow patterns in healthy children.

目的：尿流量测定法（UFM）是诊断下尿路功能障碍（LUTD）的一线无创筛查方法。本研究的目的是确定我们当地人口中健康土耳其儿童的正常UFM值。方法：共有100名5-15岁的健康女孩和62名健康男孩年，他们在2021年2月至2022年1月期间申请了伊恩努大学图尔古特Özal医学中心儿科综合诊所，被纳入本研究。使用Inoflow智能系统UFM设备测量UFM参数，包括最大流速（Qmax）、平均流速（Qavg）、排泄量（VV）、达到最大流量的时间和排泄时间，并记录所得尿流量曲线。根据儿童的性别和年龄组（5-10 11-15岁结果：5-15岁健康女性儿童的平均Qmax值年（21.8± 8.6 mL/s）显著高于男性儿童（17.98 ± 6.1 毫升/秒）（p = .003）。11-15岁年龄组儿童的VV、Qmax和Qavg值显著高于5-10岁年龄组年（p > .05）。VV、Qmax和Qavg值与年龄成正比（p = .0001）。结论：我们认为这项研究增加了关于健康儿童正常血流模式的有限知识库。

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引用次数: 0

Correction to “Hip dysfunction-related urinary incontinence and total hip arthroplasty with the direct lateral approach” “髋关节功能障碍相关性尿失禁与直接外侧入路全髋关节置换术”的矫正

IF 1.3 4区医学 Q3 UROLOGY & NEPHROLOGY

LUTS: Lower Urinary Tract Symptoms

Pub Date : 2023-07-19 DOI: 10.1111/luts.12497

Abed MH, Vasaghi-Gharamaleki B, Ghazavi MT, Nikjooy A. Hip dysfunction-related urinary incontinence and total hip arthroplasty with the direct lateral approach. Lower Urinary Tract Symptoms. 2023;15(1):11–15. doi:10.1111/luts.12466

Some of the values in Table 1 were incorrect. Please see revised table below:

We apologize for these errors.

Abed MH, Vasaghi-Gharamaleki B, Ghazavi MT, Nikjooy A.髋关节功能障碍相关性尿失禁与直接外侧入路全髋关节置换术。下尿路症状。2023;15(1):11-15。doi: 10.1111 /附近地区。12466表1中的一些值不正确。请见修改后的下表:我们为这些错误道歉。

引用次数: 0

Utilization and safety of telemedicine for pediatric lower urinary tract symptoms before and during the COVID-19 pandemic COVID-19大流行之前和期间儿童下尿路症状远程医疗的使用和安全性

IF 1.3 4区医学 Q3 UROLOGY & NEPHROLOGY

LUTS: Lower Urinary Tract Symptoms

Pub Date : 2023-07-13 DOI: 10.1111/luts.12496

Abby L. Chen, Stav Spinzi, Gunjan Agrawal, Kathleen M. Kan

Objectives

Telemedicine for pediatric lower urinary tract symptoms (pLUTS) is a relatively new mode of delivering bladder health education with scant evidence supporting current practice. We aim to examine the safety of pLUTS-related telemedicine visits surrounding the COVID-19 pandemic.

Methods

We conducted a retrospective cohort study of new pLUTS referral diagnoses to our institution's pediatric urology clinics. Demographics, wait times, and referral diagnoses were captured and compared before and after March 2020 using χ²/Fisher exact tests and t-tests. A retrospective chart review was performed for an initial telemedicine visit followed by an in-person visit to identify missed radiology, lab, or physical exam findings.

Results

Six hundred twelve patients were included from September 2018 to August 2021. Most were 5–10 years old (62.3%), female (56.2%), English speaking (86.5%), White (39.4%), and had private insurance (67.2%). Wait times were shorter for telemedicine versus in-person visits (t₁₉₀ = −3.56, p < .001). After March 2020, patients with a urinary tract infection (UTI) and females utilized in-person visits more often (p < .001). After chart review (11 patients, mean = 10.4 years), 9 (81.8%) had comorbid conditions and/or family history of lower urinary tract symptoms. None had missed clinical findings that changed management.

Conclusions

pLUTS care can be delivered via telemedicine without a significant change in patient volume and population, though additional investigations will clarify the needs of patients with specific referral diagnoses and comorbid conditions. The in-person exam can be omitted safely with proper clinical history taking, supporting future virtual programs that address delays in care within local communities.

目的儿童下尿路症状远程医疗(pLUTS)是一种相对较新的膀胱健康教育模式，目前缺乏证据支持。我们的目标是在COVID-19大流行期间检查与ppluto相关的远程医疗就诊的安全性。方法我们进行了一个回顾性队列研究新的pLUTS转诊诊断到我们机构的儿科泌尿科诊所。使用χ2/Fisher精确检验和t检验，收集了2020年3月前后的人口统计数据、等待时间和转诊诊断并进行了比较。对首次远程医疗就诊进行回顾性病历回顾，随后进行亲自就诊，以确定遗漏的放射学、实验室或体检结果。结果2018年9月至2021年8月共纳入612例患者。大多数是5-10岁(62.3%)，女性(56.2%)，说英语(86.5%)，白人(39.4%)，有私人保险(67.2%)。与面对面就诊相比，远程医疗的等待时间更短(t190 = - 3.56, p < .001)。2020年3月之后，尿路感染(UTI)患者和女性更频繁地进行了亲自就诊(p < .001)。图表回顾(11例患者，平均10.4岁)，9例(81.8%)有合并症和/或下尿路症状家族史。没有人错过了改变治疗方法的临床发现。结论:通过远程医疗提供pLUTS治疗不会对患者数量和人群产生显著影响，但进一步的调查将明确具有特定转诊诊断和合并症的患者的需求。通过适当的临床病史记录，可以安全地省略现场检查，支持未来解决当地社区护理延误的虚拟项目。

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引用次数: 0

Incidence and predictors of urinary incontinence rates post-holmium laser enucleation of prostate 钬激光前列腺摘除术后尿失禁发生率及预测因素

IF 1.3 4区医学 Q3 UROLOGY & NEPHROLOGY

LUTS: Lower Urinary Tract Symptoms

Pub Date : 2023-06-27 DOI: 10.1111/luts.12494

Mohamed Elsaqa, Yu Zhang, Harry Papaconstantinou, Marawan M. El Tayeb

Introduction

One of the main adverse outcomes following Holmium laser enucleation of the prostate (HoLEP) is the development of transient de novo urinary incontinence (UI). We aimed to evaluate the correlation of multiple risk factors to UI rates post-HoLEP.

Methods

A review of prospectively maintained 7 year database for HoLEP patients in a single center was performed. UI data at 6 week, 3 month, and 1 year follow-up intervals were assessed with bivariate and multivariate analysis of multiple potential risk factors.

Results

The study included 666 patients with median (IQR) age of 72 (66–78) years old and median (IQR) preoperative prostate volume of 89 (68–126) gm. UI was seen in 287 (43%), 100 (15%) and 26 (5.8%) at 6 week, 3 month, and 1 year follow up occasions respectively. At 6 weeks follow up, UI type was stress, urge and mixed in 121 (18.16%), 118 (17.72) and 48 (7.21%) patients respectively. Using a multivariate regression analysis, obesity and pre-operative UI were associated with postoperative UI rate at both 6 week (p = .0065, .031) and 3 month (p = .0261, .044) follow up encounters respectively. Also, larger specimen weight was another predictor for 6 week UI (p = .0399) while higher frailty score was a predictor for UI at 3 month occasion (p = .041).

Conclusion

Patients with preoperative UI, obesity, frailty, and large prostate volume are at higher risk of short-term UI post-HoLEP up to 3 months. Patients with one or more of these risk factors should be counseled regarding the higher risk of UI.

钬激光前列腺摘除(HoLEP)后的主要不良后果之一是一过性尿失禁(UI)的发展。我们的目的是评估多种危险因素与holep后UI率的相关性。方法对单中心HoLEP患者7年前瞻性数据库进行回顾性分析。随访6周、3个月和1年的UI数据通过多重潜在危险因素的双因素和多因素分析进行评估。结果666例患者中位(IQR)年龄为72(66 ~ 78)岁，术前前列腺体积中位(IQR)为89 (68 ~ 126)gm。随访6周、3个月和1年分别有287例(43%)、100例(15%)和26例(5.8%)出现尿潴留。随访6周时，尿失联类型分别为应激型、急迫型和混合型121例(18.16%)、118例(17.72)和48例(7.21%)。通过多因素回归分析，肥胖和术前尿失速与术后6周尿失速率相关(p =。0065, 0.031)和3个月(p =。0261, 0.044)分别进行后续接触。此外，较大的标本重量是6周UI的另一个预测因素(p = 0.099)，而较高的虚弱评分是3个月UI的预测因素(p = 0.041)。结论术前尿失禁、肥胖、虚弱、前列腺体积大的患者在holep术后3个月内发生短期尿失禁的风险较高。有一种或多种危险因素的患者应被告知患尿失禁的风险较高。

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引用次数: 0

Urinary incontinence in the postpartum 1-year period: Its prevalence and effect on psychosocial status of women 产后1年尿失禁的发生率及其对妇女心理社会状况的影响

IF 1.3 4区医学 Q3 UROLOGY & NEPHROLOGY

LUTS: Lower Urinary Tract Symptoms

Pub Date : 2023-06-26 DOI: 10.1111/luts.12495

Gulennur Suar, Feride Cevik, Nurgul Simal Yavuz, Nebahat Ozerdogan

Objectives

In this study, it was aimed to determine the prevalence and effect of urinary incontinence in the postpartum 1 year period on psychosocial status of women.

Methods

This study with a cross-sectional and descriptive design was conducted between 01.10.2021 and 01.04.2022. There were 406 women in the postpartum 8 weeks to 1 year period who participated in the study. The data were collected through Identifying Information Form, Edinburgh Postnatal Depression Scale, and Nottingham Health Profile.

Results

In the study, it was determined that 21.9% of the women in the postpartum period experienced urinary incontinence problems, and that the most common type of incontinence experienced was stress incontinence (62.9%). Edinburgh Postnatal Depression Scale mean score of the women who experienced urinary incontinence problems in the postpartum period was found to be significantly higher compared to those who did not experience this problem (P < .05), but no significant difference was found between the rates of those with depression risk according to the cutoff point of the scale (≥13 points). As a result of the regression analysis, it was determined that the increase in depression risk resulted not from urinary incontinence but from age and parity. It was also determined that the mean scores of the women who experienced incontinence problems from the subscales of Nottingham Health profile was significantly high (P < .05).

Conclusions

In conclusion, urinary incontinence in the postpartum period is a prevalent problem affecting approximately one-fifth of women. In addition, this problem negatively affects the psychological and social dimensions of women's health.

目的研究产后1年尿失禁的发生率及对妇女心理社会状况的影响。方法采用横断面和描述性设计，研究时间为2021年10月1日至2022年4月1日。共有406名产后8周至1年的妇女参与了这项研究。数据通过识别信息表、爱丁堡产后抑郁量表和诺丁汉健康概况收集。结果本研究确定21.9%的产后妇女出现尿失禁问题，其中最常见的尿失禁类型为应激性尿失禁(62.9%)。在爱丁堡产后抑郁量表中，出现尿失禁问题的妇女的平均得分明显高于未出现尿失禁问题的妇女(P < 0.05)，但根据量表的截止点(≥13分)，出现抑郁风险的妇女的发生率无显著差异。回归分析的结果表明，抑郁症风险的增加不是由尿失禁引起的，而是由年龄和胎次引起的。研究还发现，经历过尿失禁问题的女性在诺丁汉健康状况亚量表中的平均得分显著高(P < 0.05)。总之，产后尿失禁是一个普遍的问题，影响了大约五分之一的妇女。此外，这一问题对妇女健康的心理和社会层面产生负面影响。

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引用次数: 1

Memorial address for Emeritus Professor Osamu Yamaguchi—A man of learning 纪念名誉教授山口修——一个有学问的人

IF 1.3 4区医学 Q3 UROLOGY & NEPHROLOGY

LUTS: Lower Urinary Tract Symptoms

Pub Date : 2023-06-15 DOI: 10.1111/luts.12491

Osamu Nishizawa

引用次数: 0

Correlation of resistive index of prostatic capsular artery to clinical symptoms in men with chronic prostatitis/chronic pelvic pain syndrome 慢性前列腺炎/慢性盆腔痛综合征男性前列腺包膜动脉阻力指数与临床症状的相关性

IF 1.3 4区医学 Q3 UROLOGY & NEPHROLOGY

LUTS: Lower Urinary Tract Symptoms

Pub Date : 2023-06-14 DOI: 10.1111/luts.12493

Yasin Yitgin, Ayhan Karakose

To evaluate the relation between resistive index (RI) of prostatic capsular arteries by transrectal Doppler ultrasonography in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) and its correlation with lower urinary tract symptoms, erectile dysfunction and premature ejaculation parameters of CP/CPPS.

目的探讨慢性前列腺炎/慢性盆腔疼痛综合征(CP/CPPS)患者前列腺包膜动脉阻力指数(RI)与下尿路症状、勃起功能障碍及早泄参数的关系。方法共纳入68例慢性前列腺炎/慢性盆腔疼痛综合征患者。我们分成两组，第一组35例患者，RI≥0.7;第二组33例患者，RI < 0.7。采用国际前列腺症状评分(IPSS)、国际勃起功能指数(IIEF-5)、早泄诊断工具(PEDT)和美国国立卫生研究院慢性前列腺炎症状指数(CPSI)对所有患者进行评估。此外，所有患者均采用多普勒超声测量前列腺包膜动脉的RI。采用SPSS 18进行统计分析。p值<05被认为是显著的。结果两组患者人口学特征相似。IPSS组1为11.3±6，组2为9.7±5.3。IIEF-5分别为1组18.6±2和2组20.4±2.3。1组PEDT为12.4±5.6,2组为11.2±4。CPSI(总)组1为19.3±12.3，组2为10.6±7.7。两组患者IPSS、IIEF-5、CPSI比较，差异均有统计学意义(p <[j]， p <[j]， p <001分别)。然而，我们发现两组之间PEDT无显著差异(p = 0.19)。结论CP/CPPS患者的下尿路症状、勃起功能障碍参数与前列腺包膜动脉的RI有显著相关性，RI是评估疾病严重程度的有效、无创方法。

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