Pub Date : 2023-07-01DOI: 10.21608/mjfmct.2023.200085.1060
F. Kandeel, R. Azab
Metal phosphides as a whole and aluminum phosphide (AlP) in particular, are potent pesticides. Although phosphides are highly toxic and had a high mortality, it cannot be discarded due to their wide-spectrum applications. The aim of the study was to evaluate the prognostic value of blood lactate and C-reactive protein (CRP) levels in acute phosphide poisoned patients admitted to Menoufia University Poison Control Center. This was an analytical cross-sectional study done on cases of acute phosphide poisoning admitted to Menoufia Poison Control Center (MPCC) from the 1st of August 2022 to 31 December 2022 which fulfilled the inclusion criteria. Patient's data were collected in clinical sheets after taking written consent from patients or their guardians. Only moderately and severely poisoned patients were included in the study according to Poison Severity Score. History, clinical examination, and Echocardiography were performed. Blood samples were taken for routine laboratory investigations and measuring blood lactate and CRP levels. A total of 57 patients (26 males and 31 females) were included in the present study. In all cases, the manner of poisoning was suicide. The age in non survivors (85.9%) ranged between 14-63 years while in survivors (14.1%) was 17-39 years. Increase tablet number, low pH, low PO ₂ , high respiratory rate, low temperature, low diastolic blood pressure, high pulse rate, low ejection fraction, low potassium level, high CRP and blood lactate levels were significant predictors for phosphide poisoning mortality. Aluminum phosphide is highly toxic with a high mortality rate. CRP and blood lactate levels can be used as predictors for mortality.
{"title":"Prognostic value of blood lactate and C-reactive protein levels in acute Phosphides poisoned patients admitted to Menoufia University Poison control Center","authors":"F. Kandeel, R. Azab","doi":"10.21608/mjfmct.2023.200085.1060","DOIUrl":"https://doi.org/10.21608/mjfmct.2023.200085.1060","url":null,"abstract":"Metal phosphides as a whole and aluminum phosphide (AlP) in particular, are potent pesticides. Although phosphides are highly toxic and had a high mortality, it cannot be discarded due to their wide-spectrum applications. The aim of the study was to evaluate the prognostic value of blood lactate and C-reactive protein (CRP) levels in acute phosphide poisoned patients admitted to Menoufia University Poison Control Center. This was an analytical cross-sectional study done on cases of acute phosphide poisoning admitted to Menoufia Poison Control Center (MPCC) from the 1st of August 2022 to 31 December 2022 which fulfilled the inclusion criteria. Patient's data were collected in clinical sheets after taking written consent from patients or their guardians. Only moderately and severely poisoned patients were included in the study according to Poison Severity Score. History, clinical examination, and Echocardiography were performed. Blood samples were taken for routine laboratory investigations and measuring blood lactate and CRP levels. A total of 57 patients (26 males and 31 females) were included in the present study. In all cases, the manner of poisoning was suicide. The age in non survivors (85.9%) ranged between 14-63 years while in survivors (14.1%) was 17-39 years. Increase tablet number, low pH, low PO ₂ , high respiratory rate, low temperature, low diastolic blood pressure, high pulse rate, low ejection fraction, low potassium level, high CRP and blood lactate levels were significant predictors for phosphide poisoning mortality. Aluminum phosphide is highly toxic with a high mortality rate. CRP and blood lactate levels can be used as predictors for mortality.","PeriodicalId":18180,"journal":{"name":"Mansoura Journal of Forensic Medicine and Clinical Toxicology","volume":"186 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91480026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-02DOI: 10.21608/mjfmct.2023.181876.1059
W. Kholeif, Mohamed Radwan
Age determination is an essential step in the identification of human bony remains. Foramen magnum is a valuable landmark in the base of the skull and is of significant interest to forensic medicine, anthropology and anatomy. The aim of the study was the evaluating of the accuracy and reliability of foramen magnum parameters in age determination (among different age groups) using three-dimensional computed tomography. The present study is performed on 120 Egyptians from different age groups (from 1 year up to 65 years). The length of the foramen magnum (LFM) and the width of the foramen magnum (WFM) were measured on the 3D CT models. Then, foramen magnum index (FMI) and foramen magnum area (FMA) were calculated. The different age groups (1 – 9, 10 – 19, 20 – 29, 30 -39, 40 – 49,50 – 59 and 60+ years) show the mean LFM was 26.90, 35.75, 34.66, 34.42, 33.88, 33.27 and 32.50 mm respectively. Mean WFM was 20.90, 25.67, 29.47, 28.75, 28.47, 27.53 and 28.0 mm respectively. Mean FMI was 1.29, 1.39, 1.18, 1.20, 1.20, 1.21 and 1.16 mm respectively. Mean FMA was 444.2, 721.7, 804.3, 783.0, 759.3, 720.8 and 718.1 mm respectively. These values reveal that there is a significant difference between the four studied parameters and different age groups. This study elucidated that LFM decrease and WFM increase with aging. Subsequently, FMI tends to decrease with age. There was a weak positive correlation between age and LFM, WFM and FMA and there was a negative correlation between age
{"title":"A COMPUTED TOMOGRAPHIC ANALYSIS OF FORAMEN MAGNUM PARAMETERS FOR AGE DETERMINATION IN A SAMPLE OF EGYPTIANS","authors":"W. Kholeif, Mohamed Radwan","doi":"10.21608/mjfmct.2023.181876.1059","DOIUrl":"https://doi.org/10.21608/mjfmct.2023.181876.1059","url":null,"abstract":"Age determination is an essential step in the identification of human bony remains. Foramen magnum is a valuable landmark in the base of the skull and is of significant interest to forensic medicine, anthropology and anatomy. The aim of the study was the evaluating of the accuracy and reliability of foramen magnum parameters in age determination (among different age groups) using three-dimensional computed tomography. The present study is performed on 120 Egyptians from different age groups (from 1 year up to 65 years). The length of the foramen magnum (LFM) and the width of the foramen magnum (WFM) were measured on the 3D CT models. Then, foramen magnum index (FMI) and foramen magnum area (FMA) were calculated. The different age groups (1 – 9, 10 – 19, 20 – 29, 30 -39, 40 – 49,50 – 59 and 60+ years) show the mean LFM was 26.90, 35.75, 34.66, 34.42, 33.88, 33.27 and 32.50 mm respectively. Mean WFM was 20.90, 25.67, 29.47, 28.75, 28.47, 27.53 and 28.0 mm respectively. Mean FMI was 1.29, 1.39, 1.18, 1.20, 1.20, 1.21 and 1.16 mm respectively. Mean FMA was 444.2, 721.7, 804.3, 783.0, 759.3, 720.8 and 718.1 mm respectively. These values reveal that there is a significant difference between the four studied parameters and different age groups. This study elucidated that LFM decrease and WFM increase with aging. Subsequently, FMI tends to decrease with age. There was a weak positive correlation between age and LFM, WFM and FMA and there was a negative correlation between age","PeriodicalId":18180,"journal":{"name":"Mansoura Journal of Forensic Medicine and Clinical Toxicology","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84381256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-25DOI: 10.21608/mjfmct.2023.201132.1061
Ereny Fekry, Mona M Awny, George Refaat, Horeya Arafat
ABSTRACT
摘要
{"title":"Ameliorative effect of Silybum marianum extract \"Milk thistle\" against Lithium-induced cardiac toxicity in adult male albino rats.","authors":"Ereny Fekry, Mona M Awny, George Refaat, Horeya Arafat","doi":"10.21608/mjfmct.2023.201132.1061","DOIUrl":"https://doi.org/10.21608/mjfmct.2023.201132.1061","url":null,"abstract":"ABSTRACT","PeriodicalId":18180,"journal":{"name":"Mansoura Journal of Forensic Medicine and Clinical Toxicology","volume":"255 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73237360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-24DOI: 10.21608/mjfmct.2023.206490.1062
M. Salama
{"title":"The exposome: A new paradigm in public health research","authors":"M. Salama","doi":"10.21608/mjfmct.2023.206490.1062","DOIUrl":"https://doi.org/10.21608/mjfmct.2023.206490.1062","url":null,"abstract":"","PeriodicalId":18180,"journal":{"name":"Mansoura Journal of Forensic Medicine and Clinical Toxicology","volume":"246 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90862811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-13DOI: 10.21608/mjfmct.2023.177759.1058
A. Elkady, Rasha Elhaddad Ali Mousa, Mai Abdelkader, Hend G. Aref, Azza Hassan
{"title":"A Comprehensive Review on Bisphenol A (BPA) Toxicity Updates: Controversy Is Not Over Yet","authors":"A. Elkady, Rasha Elhaddad Ali Mousa, Mai Abdelkader, Hend G. Aref, Azza Hassan","doi":"10.21608/mjfmct.2023.177759.1058","DOIUrl":"https://doi.org/10.21608/mjfmct.2023.177759.1058","url":null,"abstract":"","PeriodicalId":18180,"journal":{"name":"Mansoura Journal of Forensic Medicine and Clinical Toxicology","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72730730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.21608/mjfmct.2023.176705.1057
Heba Allah Abd El Rahman, M. Hussein, Doaa Khedr
{"title":"Metric Analysis of Sella Turcica for Sex Identification Using Multidetector Computed Tomography in a Sample of Adult Egyptians.","authors":"Heba Allah Abd El Rahman, M. Hussein, Doaa Khedr","doi":"10.21608/mjfmct.2023.176705.1057","DOIUrl":"https://doi.org/10.21608/mjfmct.2023.176705.1057","url":null,"abstract":"","PeriodicalId":18180,"journal":{"name":"Mansoura Journal of Forensic Medicine and Clinical Toxicology","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73902922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.21608/mjfmct.2022.176319.1056
Ereny Fekry, Mona M Awny, Samy Y Makary, Abeer E. El-Metwally
Spleen. Cyclophosphamide (CTX) is an effective anticancer therapy. It is known to cause oxidative stress and cytotoxic effects, especially on the immune system. Pentoxifylline and Nigella sativa seeds both possess antioxidant and anti-inflammatory properties. This study explores the ameliorative impact of both pentoxifylline and nigella sativa over the splenic damage induced by cyclophosphamide. Thirty-six adult male albino rats were separated into six groups from six each and received treatment for 10 days. Group I (control) received saline 0.9% solution orally via intragastric tube, group II received pentoxifylline (150 mg/kg) orally, group III received nigella sativa oil (20 mg/day) orally, group IV received a single intraperitoneal injection (IP) of CTX (200 mg/kg), group V received pentoxifylline (150 mg/day) orally for 10 days and at the 8th-day animals received single IP injection of CTX (200 mg/kg), group VI received nigella sativa oil (20 mg/day) orally for 10 days and similarly at the 8th-day animals received single IP injection of CTX (200 mg/kg). Light microscopic and ultrastructure changes in the spleen of the different experimental groups were examined. CTX induced splenic damage in the form of a disrupted and detached capsule of the spleen, lymphocyte loss with marked thickening and dilatation of the central artery in the white pulp, and cellular loss and congested blood sinusoids in the red pulp. The use of pentoxifylline and nigella sativa resulted in the restoration of splenic tissue. Pentoxifylline showed a more protective effect than nigella sativa on the splenic tissue against CTX-induced damage.
{"title":"Protective effect of Pentoxifylline versus Nigella sativa against Cyclophosphamide induced splenic damage in adult male albino rats.","authors":"Ereny Fekry, Mona M Awny, Samy Y Makary, Abeer E. El-Metwally","doi":"10.21608/mjfmct.2022.176319.1056","DOIUrl":"https://doi.org/10.21608/mjfmct.2022.176319.1056","url":null,"abstract":"Spleen. Cyclophosphamide (CTX) is an effective anticancer therapy. It is known to cause oxidative stress and cytotoxic effects, especially on the immune system. Pentoxifylline and Nigella sativa seeds both possess antioxidant and anti-inflammatory properties. This study explores the ameliorative impact of both pentoxifylline and nigella sativa over the splenic damage induced by cyclophosphamide. Thirty-six adult male albino rats were separated into six groups from six each and received treatment for 10 days. Group I (control) received saline 0.9% solution orally via intragastric tube, group II received pentoxifylline (150 mg/kg) orally, group III received nigella sativa oil (20 mg/day) orally, group IV received a single intraperitoneal injection (IP) of CTX (200 mg/kg), group V received pentoxifylline (150 mg/day) orally for 10 days and at the 8th-day animals received single IP injection of CTX (200 mg/kg), group VI received nigella sativa oil (20 mg/day) orally for 10 days and similarly at the 8th-day animals received single IP injection of CTX (200 mg/kg). Light microscopic and ultrastructure changes in the spleen of the different experimental groups were examined. CTX induced splenic damage in the form of a disrupted and detached capsule of the spleen, lymphocyte loss with marked thickening and dilatation of the central artery in the white pulp, and cellular loss and congested blood sinusoids in the red pulp. The use of pentoxifylline and nigella sativa resulted in the restoration of splenic tissue. Pentoxifylline showed a more protective effect than nigella sativa on the splenic tissue against CTX-induced damage.","PeriodicalId":18180,"journal":{"name":"Mansoura Journal of Forensic Medicine and Clinical Toxicology","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90113002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.21608/mjfmct.2023.175884.1055
Situhom El Agamy, Ghadeer Elsheikh, Hend Omara, Nagwa Habib
ABSTRACT
摘要
{"title":"Pattern and Risk Factors of Suicide Mortality in Children among Cases arrived at Menoufia University Hospitals and analysis through the Suicide Assessment Five-Step Evaluation and Triage","authors":"Situhom El Agamy, Ghadeer Elsheikh, Hend Omara, Nagwa Habib","doi":"10.21608/mjfmct.2023.175884.1055","DOIUrl":"https://doi.org/10.21608/mjfmct.2023.175884.1055","url":null,"abstract":"ABSTRACT","PeriodicalId":18180,"journal":{"name":"Mansoura Journal of Forensic Medicine and Clinical Toxicology","volume":"79 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87926499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.21608/mjfmct.2022.168742.1053
O. Sweilum, Samy Hammad, Naira Gerges, A. Zanaty, E. Badr, Rasha Mammdouh
ABSTRACT
摘要
{"title":"Human Sex determination from the dental pulp tissue using Polymerase Chain Reaction (PCR)","authors":"O. Sweilum, Samy Hammad, Naira Gerges, A. Zanaty, E. Badr, Rasha Mammdouh","doi":"10.21608/mjfmct.2022.168742.1053","DOIUrl":"https://doi.org/10.21608/mjfmct.2022.168742.1053","url":null,"abstract":"ABSTRACT","PeriodicalId":18180,"journal":{"name":"Mansoura Journal of Forensic Medicine and Clinical Toxicology","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74631345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.21608/mjfmct.2023.175169.1054
A. Elshazly, Neama M Taha, N. Sarg, A. Hussein, Yasmeen Mohammed Ismail El Sayed, H. Fakher, A. Ali
{"title":"Bone Marrow Derived Mesenchymal Stem Cells Versus Astaxanthin in Treatment of Toxic Effect of 5-Fluorouracil on Gastric mucosa of Male Albino Rats","authors":"A. Elshazly, Neama M Taha, N. Sarg, A. Hussein, Yasmeen Mohammed Ismail El Sayed, H. Fakher, A. Ali","doi":"10.21608/mjfmct.2023.175169.1054","DOIUrl":"https://doi.org/10.21608/mjfmct.2023.175169.1054","url":null,"abstract":"","PeriodicalId":18180,"journal":{"name":"Mansoura Journal of Forensic Medicine and Clinical Toxicology","volume":"144 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76531191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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