P. Brandão, Nanda Isele Gallas Duarte, Patrícia Gonçalves Soares, Francilene Mesquita, Suerli Carvalho Costa
{"title":"Right to health and Hansen’s disease: the voice of girls and women affected by Hansen’s disease","authors":"P. Brandão, Nanda Isele Gallas Duarte, Patrícia Gonçalves Soares, Francilene Mesquita, Suerli Carvalho Costa","doi":"10.47276/lr.93.2.1161","DOIUrl":"https://doi.org/10.47276/lr.93.2.1161","url":null,"abstract":"","PeriodicalId":18196,"journal":{"name":"Leprosy review","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44148342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction of ulnar claw hand – A comparative study of extensor carpi radialis longus (ECRL) and flexor digitorum superficialis (FDS) as the motor unit of choice","authors":"Imran Sajid, Sabeel Ahmad","doi":"10.47276/lr.93.2.102","DOIUrl":"https://doi.org/10.47276/lr.93.2.102","url":null,"abstract":"","PeriodicalId":18196,"journal":{"name":"Leprosy review","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43604679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Renni Yuniati, W. Riawan, Aris Widayati, M. Khrisna, T. Kristina
{"title":"Histopathology of SUMO in TGF-β1 signaling in neural lesions of leprosy reversal reactions","authors":"Renni Yuniati, W. Riawan, Aris Widayati, M. Khrisna, T. Kristina","doi":"10.47276/lr.93.2.138","DOIUrl":"https://doi.org/10.47276/lr.93.2.138","url":null,"abstract":"","PeriodicalId":18196,"journal":{"name":"Leprosy review","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41599990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Bhalla, K. Poonia, Surbhi Jain, G. Thami, Priyanka Sharma
Introduction Pure neuritic leprosy (PNL) is characterized by enlargement of peripheral nerves, sensory loss without any cutaneous lesions, skin slit smear negativity and a variable lepromin test and histopathology. Methods This was a retrospective analysis of the clinical records of all the leprosy patients enrolled in the Leprosy Clinic, during the years 1999–2019. The patient records fulfilling the diagnostic criteria of PNL were considered for analysis. Results A total of 1225 patients registered leprosy cases, out of which 41 (3.3%) patients were diagnosed with PNL. Mean age was 31 years and 80% patients were male. Multiple nerves were affected in 25 (61%) patients and one nerve was found to be affected in only 16 (39%) patients. Grade 2 deformities were seen in 26 (63%) patients. All patients were treated with multi-drug therapy 25 patients received the multibacillary regimen and 16 received the paucibacillary regimen; 27 (66%) patients completed the treatment as prescribed. Conclusion Leprosy is the most common treatable cause of peripheral neuropathy. Therefore, early detection of leprosy neuropathy is important for preventing deformities and disabilities. It may be advisable to treat all PNL cases with the multibacillary multidrug therapy in view of higher rate of deformities.
{"title":"Clinical profile of patients with pure neuritic leprosy: 20 years’ experience at a tertiary referral centre from North India","authors":"M. Bhalla, K. Poonia, Surbhi Jain, G. Thami, Priyanka Sharma","doi":"10.47276/lr.93.2.131","DOIUrl":"https://doi.org/10.47276/lr.93.2.131","url":null,"abstract":"Introduction Pure neuritic leprosy (PNL) is characterized by enlargement of peripheral nerves, sensory loss without any cutaneous lesions, skin slit smear negativity and a variable lepromin test and histopathology. Methods This was a retrospective analysis of the clinical records of all the leprosy patients enrolled in the Leprosy Clinic, during the years 1999–2019. The patient records fulfilling the diagnostic criteria of PNL were considered for analysis. Results A total of 1225 patients registered leprosy cases, out of which 41 (3.3%) patients were diagnosed with PNL. Mean age was 31 years and 80% patients were male. Multiple nerves were affected in 25 (61%) patients and one nerve was found to be affected in only 16 (39%) patients. Grade 2 deformities were seen in 26 (63%) patients. All patients were treated with multi-drug therapy 25 patients received the multibacillary regimen and 16 received the paucibacillary regimen; 27 (66%) patients completed the treatment as prescribed. Conclusion Leprosy is the most common treatable cause of peripheral neuropathy. Therefore, early detection of leprosy neuropathy is important for preventing deformities and disabilities. It may be advisable to treat all PNL cases with the multibacillary multidrug therapy in view of higher rate of deformities.","PeriodicalId":18196,"journal":{"name":"Leprosy review","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48512744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Leprosy stigma and its effect on the marriage experience of leprosy affected people and their descendants: the case of Addis-Tesfa Hiwot settlements in Ethiopia","authors":"Hunegnaw Ayele","doi":"10.47276/lr.93.2.149","DOIUrl":"https://doi.org/10.47276/lr.93.2.149","url":null,"abstract":"","PeriodicalId":18196,"journal":{"name":"Leprosy review","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45253463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Lockwood, G. Penna, S. Lambert, V. Pai, S. Walker
Diana N. J. Lockwooda,b, Gerson O. Pennac, Saba Lambertd,e, Vivek Vasudev Paif & Stephen L. Walkerg,h aEmeritus Professor of Tropical Medicine, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK ORCID: https://orcid.org/0000-0003-2865-8966 bConsultant Physician (retired), Hospital for Tropical Diseases, University College London Hospitals NHS Foundation Trust, London, UK cTropical Medicine Centre, University of Brasília, Fiocruz School of Government Brasília, Brazil ORCID: https://orcid.org/0000-0001-8967-536X dResearch Fellow, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK ORCID: https://orcid.org/0000-0003-4376-5495 eAll Africa Leprosy Research and Training Centre, Addis Ababa, Ethiopia fDirector, Bombay Leprosy Project, Mumbai, Maharashtra, India ORCID: https://orcid.org/0000-0001-7282-9879 gConsultant Dermatologist, Hospital for Tropical Diseases and Department of Dermatology, University College London Hospitals NHS Foundation Trust, London, UK ORCID: https://orcid.org/0000-0002-2034-8376 hFaculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
Diana N. J. Lockwooda,b, Gerson O. Pennac, Saba Lambertd,e, Vivek Vasudev Paif和Stephen L. walker，英国伦敦伦敦卫生和热带医学学院传染病和热带病学院热带医学名誉教授。https://orcid.org/0000-0003-2865-8966 b顾问医师(退休)，伦敦大学学院医院国民保健服务基金会信托基金，伦敦，英国热带医学中心，Brasília，菲奥克鲁兹政府学院Brasília，巴西ORCID: https://orcid.org/0000-0001-8967-536X，伦敦，伦敦，卫生和热带医学学院，传染病和热带病学院研究员，伦敦，英国ORCID:https://orcid.org/0000-0003-4376-5495埃塞俄比亚亚的斯亚贝巴全非洲麻风病研究和培训中心印度马哈拉施特拉邦孟买孟买麻风病项目主任ORCID: https://orcid.org/0000-0001-7282-9879英国伦敦大学学院伦敦医院国民保健服务基金会信托基金热带病医院和皮肤科顾问皮肤科医生ORCID:https://orcid.org/0000-0002-2034-8376 h传染病和热带病学院，伦敦卫生和热带医学学院，英国伦敦
{"title":"Safer and newer antimicrobial drugs for leprosy – time to test monthly ROM in an adequately powered randomised trial?","authors":"D. Lockwood, G. Penna, S. Lambert, V. Pai, S. Walker","doi":"10.47276/lr.93.2.96","DOIUrl":"https://doi.org/10.47276/lr.93.2.96","url":null,"abstract":"Diana N. J. Lockwooda,b, Gerson O. Pennac, Saba Lambertd,e, Vivek Vasudev Paif & Stephen L. Walkerg,h aEmeritus Professor of Tropical Medicine, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK ORCID: https://orcid.org/0000-0003-2865-8966 bConsultant Physician (retired), Hospital for Tropical Diseases, University College London Hospitals NHS Foundation Trust, London, UK cTropical Medicine Centre, University of Brasília, Fiocruz School of Government Brasília, Brazil ORCID: https://orcid.org/0000-0001-8967-536X dResearch Fellow, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK ORCID: https://orcid.org/0000-0003-4376-5495 eAll Africa Leprosy Research and Training Centre, Addis Ababa, Ethiopia fDirector, Bombay Leprosy Project, Mumbai, Maharashtra, India ORCID: https://orcid.org/0000-0001-7282-9879 gConsultant Dermatologist, Hospital for Tropical Diseases and Department of Dermatology, University College London Hospitals NHS Foundation Trust, London, UK ORCID: https://orcid.org/0000-0002-2034-8376 hFaculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK","PeriodicalId":18196,"journal":{"name":"Leprosy review","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44749367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dr William Felton Ross. 9 May 1927–3 March 2022","authors":"Jim Oehrig","doi":"10.47276/lr.93.2.175","DOIUrl":"https://doi.org/10.47276/lr.93.2.175","url":null,"abstract":"","PeriodicalId":18196,"journal":{"name":"Leprosy review","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46423164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zin Mar Theint, Zin Lynn Htun, Khin Mar Swe, Kathy Kuipers, P. Kuipers
This short report describes the rationale for and process of developing and refining a manual to assist professionals, workers, families, volunteers, and people with disabilities in low-and middle-income countries (LMIC), to make better use of appropriate and accessible communications technology. The manual is intended as a basic step towards enhancing disability and leprosy services where they are not accessible and/or affordable to people in remote areas of LMIC. A semi-formal process comprising several layers of feedback and review, and sub-sequent preliminary evaluation was encouraging. It suggests that the pilot version warrants further implementation as well as more formal research to rigorously evaluate the effectiveness and to refine the content of the manual.
{"title":"Remote disability and leprosy services via basic communications technology","authors":"Zin Mar Theint, Zin Lynn Htun, Khin Mar Swe, Kathy Kuipers, P. Kuipers","doi":"10.47276/lr.93.2.166","DOIUrl":"https://doi.org/10.47276/lr.93.2.166","url":null,"abstract":"This short report describes the rationale for and process of developing and refining a manual to assist professionals, workers, families, volunteers, and people with disabilities in low-and middle-income countries (LMIC), to make better use of appropriate and accessible communications technology. The manual is intended as a basic step towards enhancing disability and leprosy services where they are not accessible and/or affordable to people in remote areas of LMIC. A semi-formal process comprising several layers of feedback and review, and sub-sequent preliminary evaluation was encouraging. It suggests that the pilot version warrants further implementation as well as more formal research to rigorously evaluate the effectiveness and to refine the content of the manual.","PeriodicalId":18196,"journal":{"name":"Leprosy review","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45107747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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