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[Children with developmental delay]. [发育迟缓的儿童]。
Q4 Medicine Pub Date : 2025-08-27
Roselin R van der Torren, Sytske E Nawijn, Tjitske Kleefstra, Annette P M van den Elzen

Children with developmental delay develop more slowly than their peers in one or more developmental domains. This article discusses how to recognize developmental delay and key considerations for history taking, physical examination, and developmental assessment. The differential diagnosis is extensive; in addition to genetic, neurological and metabolic causes, developmental delay can result from acquired biological or social factors. The updated Dutch guideline 'Etiology of Developmental Delay and/or Intellectual Disability' (2025) outlines the diagnostic and therapeutic approaches. Children with developmental delay benefit from multidisciplinary therapy and special-needs education. The article also highlights the roles of various specialties within the care process.

发育迟缓儿童在一个或多个发展领域比同龄人发展得更慢。本文讨论了如何识别发育迟缓,以及记录病史、体格检查和发育评估的关键考虑因素。鉴别诊断是广泛的;除了遗传、神经和代谢原因外,后天的生物或社会因素也可能导致发育迟缓。更新后的荷兰指南“发育迟缓和/或智力残疾的病因学”(2025)概述了诊断和治疗方法。发育迟缓儿童受益于多学科治疗和特殊需要教育。文章还强调了各种专业在护理过程中的作用。
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引用次数: 0
[Challenges concerning lymphadenopathy after COVID-19 vaccination]. 【COVID-19疫苗接种后淋巴结病变的挑战】。
Q4 Medicine Pub Date : 2025-08-25
Linda Davidson, Cees van Nieuwkoop, Tamara N Platteel, Marina S Kartachova, Agnes C Kant, Florence P A M van Hunsel

Reactive lymphadenopathy after COVID-19 vaccination occurs frequently and usually recovers within 1-2 weeks. It can, however, persist for more than six months in some cases. Axillary lymphadenopathy at the site of vaccination is most common. Cervical and supraclavicular lymphadenopathy is also reported. A wait-and-see approach for 2-3 weeks seems justified when time between onset of lymphadenopathy and covid-19 vaccination is several days to weeks, there is no progression, lymphadenopathy is unilateral and localised axillary or cervical in patients without a history of malignancy and without alarm symptoms. In cases of persistent lymphadenopathy, ultrasound of the affected lymph node is recommended. In cases of unilateral axillary lymphadenopathy in women, breast examination with mammography and/or breast ultrasound is also warranted. In the absence of any abnormalities referral to secondary care can be delayed for 8-12 weeks. After this time period we advise referral to secondary care to exclude any underlying illness.

COVID-19疫苗接种后反应性淋巴结病经常发生,通常在1-2周内恢复。然而,在某些情况下,它可以持续六个月以上。腋窝淋巴结病在接种部位是最常见的。颈椎和锁骨上淋巴结病也有报道。当淋巴结病发病和covid-19疫苗接种之间的时间为数天至数周,没有进展,没有恶性肿瘤病史且没有警报症状的患者的淋巴结病是单侧和局部腋窝或宫颈时,采取2-3周的观望方法似乎是合理的。在持续性淋巴结病变的病例中,建议对受影响的淋巴结进行超声检查。在女性单侧腋窝淋巴结病的病例中,乳房x光检查和/或乳房超声检查也是必要的。在没有任何异常的情况下,转诊到二级保健可延迟8-12周。在这段时间后,我们建议转诊到二级保健排除任何潜在的疾病。
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引用次数: 0
[Replace disposable cellulose pads with environmentally friendly alternative: multicentre study of usage trends and environmental impact]. [用环境友好的替代品取代一次性纤维素垫:使用趋势和环境影响的多中心研究]。
Q4 Medicine Pub Date : 2025-08-21
Guus Witte, Kim E van Nieuwenhuizen, Femke A van der Zant, Roos F Bleckman, Bastiaan A Blank, Annemarie M Leliveld-Kors, Schelto Kruijff, Frank W Jansen, Anne C van der Eijk

Objective: Gain insight into usage, environmental impact and user experience of different absorbent mats.

Design: Prospective implementation study and life cycle assessments (LCAs).

Method: Conducted at the LUMC and UMCG, insight into usage of disposable cellulose pads was obtained through focus groups, interviews and surveys. LCAs analysed the environmental impact of disposable and reusable mats. User experience was evaluated through surveys for patients and healthcare professionals. Finally, functionality and usage trends were evaluated.

Results: Findings reveal that disposable pads are often used for incorrect indications due to convenience and ineffective safety behaviour. The reusable mat has a lower environmental impact than the disposable pad. After implementing the reusable mat, a reduction in usage numbers is acquired and usage is perceived positively.

Conclusion: The environmental impact of absorbent mats in healthcare can be reduced by using them more efficiently and replacing them with reusable mats while maintaining a positive user experience.

目的:了解不同吸水垫的使用情况、环境影响和用户体验。设计:前瞻性实施研究和生命周期评估(LCAs)。方法:在LUMC和UMCG进行,通过焦点小组、访谈和调查来了解一次性纤维素垫的使用情况。LCAs分析了一次性垫和可重复使用垫对环境的影响。通过对患者和医疗保健专业人员的调查来评估用户体验。最后,对功能和使用趋势进行了评估。结果:调查结果显示,由于使用方便和安全行为不佳,一次性卫生巾经常用于不正确的适应症。可重复使用的垫子比一次性垫子对环境的影响更小。在实施可重复使用的垫子后,获得了使用数量的减少,并且使用是积极的。结论:在保持良好的用户体验的同时,可以通过更有效地使用吸收垫和更换可重复使用垫来减少医疗保健中吸收垫对环境的影响。
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引用次数: 0
[A painful swelling in the groin]. [腹股沟疼痛的肿胀]。
Q4 Medicine Pub Date : 2025-08-21
Siem A Willems, K T Buddingh, Marcus A M Brouwers

A 38-year-old man presented with a painful swelling in the left groin radiating to the scrotum for three days. Suspecting an incarcerated inguinal hernia, an exploration was performed in the operating room, which revealed vasitis (inflammation of the vas deferens) instead. A urine culture (including an STI test) was obtained, and an empirical 14-day course of ciprofloxacin was initiated.

男,38岁,左腹股沟疼痛肿胀,向阴囊放射三天。怀疑为嵌顿性腹股沟疝,在手术室进行探查,结果显示输精管炎(输精管炎症)。进行尿液培养(包括STI测试),并开始为期14天的环丙沙星经验疗程。
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引用次数: 0
[Neurocutaneous dysesthesia, an invisible ailment]. 神经皮肤感觉不良,一种看不见的疾病。
Q4 Medicine Pub Date : 2025-08-19
Liza H Breedijk, Markus W Hollmann, Patrick M H J Kemperman

Neurocutaneous dysesthesia manifests as abnormal sensations, such as itching, pain, or burning, often without visible skin lesions. The condition is caused by peripheral or central nerve damage or compression. There are many different forms of neurocutaneous dysesthesia, depending on the location and the nerves involved. A well-known example is post-herpetic neuralgia, whereas brachioradial pruritus and notalgia paresthetica are less recognized. Diagnosis requires a thorough medical history and recognition of typical clinical patterns. Treatment ranges from local therapies to systemic agents.

神经皮肤感觉不良表现为异常感觉,如瘙痒、疼痛或灼烧,通常没有可见的皮肤损伤。这种情况是由周围或中枢神经损伤或压迫引起的。有许多不同形式的神经性皮肤感觉不良,取决于部位和涉及的神经。一个众所周知的例子是疱疹后神经痛,而肱桡瘙痒和感觉异常痛症则不太为人所知。诊断需要全面的病史和对典型临床模式的认识。治疗范围从局部治疗到全身治疗。
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引用次数: 0
[Medicine's collective memory: a contribution to the debate on gendersensitive medicine]. [医学的集体记忆:对性别敏感医学辩论的贡献]。
Q4 Medicine Pub Date : 2025-08-14
Fleur Helewaut, Rina Knoeff, Aranka V Ballering

In this article, we explore how the genderhealth gap has developed from a cultural-historical perspective, through the lens of a general practitioner, health scientist and medical historian. We describe the application of the concept of 'the collective memory' to medicine as a discipline, and show how it shapes medicine's identity. Awareness of the collective memory reveals underlying biases and could result in a sustainable and systematic change in medicine that ultimately improves the health of both women and men. When physicians critically examine the past in collaboration with historians, room to reflect on current practices is created. Why do we think the way we think, and act the way we act? This collaborative examination of the past allows us to understand the roots of the genderhealthgap and to work towards increasingly gender-sensitive medicine.

在这篇文章中,我们通过全科医生、健康科学家和医学历史学家的视角,从文化历史的角度探讨性别健康差距是如何发展的。我们描述了“集体记忆”概念在医学上作为一门学科的应用,并展示了它如何塑造医学的身份。对集体记忆的认识揭示了潜在的偏见,并可能导致医学上可持续和系统的变化,最终改善女性和男性的健康。当医生与历史学家合作批判性地审视过去时,就创造了反思当前做法的空间。为什么我们要这样想,为什么我们要这样做?这种对过去的合作审查使我们能够了解性别健康差距的根源,并努力实现对性别问题日益敏感的医学。
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引用次数: 0
[A man with bilateral spontaneous flank ecchymoses]. [伴有双侧自发性侧翼瘀斑的男子]。
Q4 Medicine Pub Date : 2025-08-13
Sofie de Wilde-van der Plaat, Douwe Rijpsma

This case concerns a 66-year old man with lower abdominal and groin pain and bilateral spontaneous flank ecchymoses, based on a spontaneous bilateral iliopsoas hematoma. This case illustrates that, although uncommon, an iliopsoas hematoma can be the cause of a Grey Turner sign, indicating a retroperitoneal haemorrhage.

本病例涉及一名66岁男性,因自发性双侧髂腰肌血肿而出现下腹部和腹股沟疼痛和双侧自发性侧腹瘀斑。本病例表明,虽然不常见,但髂腰肌血肿可能是格雷特纳征的原因,表明腹膜后出血。
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引用次数: 0
[Management of pediatric hip fractures]. [小儿髋部骨折的处理]。
Q4 Medicine Pub Date : 2025-08-11
Wesley W E S Theunissen, Hidde D Veldman, M Adhiambo Witlox

Pediatric hip fractures are rare and pose significant clinical challenges in their treatment. These fractures typically result from high-energy trauma, while low-energy mechanisms should raise suspicion for pathological fractures or non-accidental injury. Pediatric hip fractures are associated with high complication rates, including avascular necrosis, coxa vara, non-union, and leg-length discrepancies. These complications arise from the unique anatomy of the proximal femur in children, particularly the presence of the growth plate and the vulnerable arterial blood supply. Early surgical intervention with anatomic reduction and stable internal fixation is crucial. This review article summarizes the key principles of pediatric hip fracture management and the potential complications.

小儿髋部骨折是罕见的,对其治疗提出了重大的临床挑战。这些骨折通常由高能创伤引起,而低能机制应引起对病理性骨折或非意外损伤的怀疑。儿童髋部骨折并发症发生率高,包括无血管坏死、髋内翻、骨不连和腿长差异。这些并发症源于儿童股骨近端独特的解剖结构,特别是生长板的存在和脆弱的动脉血液供应。早期手术干预解剖复位和稳定内固定是至关重要的。本文综述了小儿髋部骨折处理的主要原则及可能的并发症。
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引用次数: 0
[Inpatient treatment for refractory PSS]. [难治性PSS的住院治疗]。
Q4 Medicine Pub Date : 2025-08-05
Jordy J E Rovers, Sara Zijderveld, Martina T Mulder, Lineke M Tak, Else M Bisseling

Persistent somatic symptoms (PSS) is an umbrella term for physical symptoms lasting several months that limit daily functioning or cause significant distress, regardless of their etiology. Treatment can be effective, but in refractory PSS, which is often accompanied by severe functional impairments, treatment may fail or even have adverse effects. In clinical practice, inpatient admission is often considered in such cases. Two case studies illustrate the challenges and outcomes of inpatient treatment for refractory PSS. Patient A benefited from a structured and planned biopsychosocial approach, which led to improved functioning and reduced suicidality. In contrast, Patient B had a negative experience due to the absence of jointly established expectations and disappointment with the diagnostic procedures. These cases highlight the importance of a well-prepared admission process, in which the patient, relatives, and involved healthcare professionals discuss expectations and reach agreement on concrete goals to enable an effective start to the recovery process.

持续性躯体症状(PSS)是持续数月的躯体症状的总称,无论其病因如何,这些症状限制了日常功能或引起严重的痛苦。治疗是有效的,但难治性PSS往往伴有严重的功能损伤,治疗可能失败甚至产生不良反应。在临床实践中,在这种情况下经常考虑住院治疗。两个案例研究说明了难治性PSS住院治疗的挑战和结果。患者A受益于结构化和有计划的生物心理社会治疗方法,这导致了功能的改善和自杀率的降低。相比之下,由于缺乏共同建立的期望和对诊断程序的失望,患者B有一个消极的经历。这些病例强调了一个准备充分的入院过程的重要性,在这个过程中,患者、亲属和相关的医疗保健专业人员讨论期望并就具体目标达成一致,以使恢复过程有效地开始。
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引用次数: 0
[Can the Assessment of Burden of Chronic Conditions (ABCC) Tool contribute to person-centered care?] 慢性疾病负担评估(ABCC)工具能促进以人为本的护理吗?]
Q4 Medicine Pub Date : 2025-08-04
Loraine H L Peters, Onno C P van Schayck, Annerika H M Gidding-Slok

Chronic conditions represent an increasing public health challenge. While concepts like person-centered care, shared decision-making, and self-management are increasingly promoted, their practical realization remains difficult within our disease-centered healthcare system. The Assessment of Burden of Chronic Conditions (ABCC) tool may contribute to a more person-centered approach within the current healthcare system. This tool can support patients and healthcare providers in developing personalized care plans by measuring and visualizing perceived disease burden. Research indicates that the questions within the ABCC tool are valid and reliable for COPD, asthma, type 2 diabetes, chronic heart failure, osteoarthritis, and colorectal cancer. An effectiveness study found that using the tool resulted in significant differences in perceived quality of care and patient activation compared to control. However, outcomes like quality of life and well-being showed no significant differences in this study. Future research should focus on validation for multimorbidity, long-term effects, and implementation strategies.

慢性疾病是一项日益严峻的公共卫生挑战。虽然以人为本的护理、共同决策和自我管理等概念日益得到推广,但在我们以疾病为中心的医疗保健系统中,它们的实际实现仍然很困难。慢性疾病负担评估(ABCC)工具可能有助于在当前的医疗保健系统中采用更以人为本的方法。该工具可以通过测量和可视化感知疾病负担来支持患者和医疗保健提供者制定个性化护理计划。研究表明,ABCC工具中的问题对于慢性阻塞性肺病、哮喘、2型糖尿病、慢性心力衰竭、骨关节炎和结直肠癌是有效和可靠的。一项有效性研究发现,与对照组相比,使用该工具在感知护理质量和患者激活方面产生了显著差异。然而,在这项研究中,生活质量和幸福感等结果没有显着差异。未来的研究应集中在多病性、长期效果和实施策略的验证上。
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引用次数: 0
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Nederlands tijdschrift voor geneeskunde
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