Frederico Ehff, G. Cas, R. Santos, Guedes-de-Aguiar Eo, G. Cr, C. R. Kütter, L. Machado-Rocha, P. Fg, A. Rosa, R. F. Neves, E. Moreira-Marconi, P. L. Souza, S. Paoli, Roberto Alcántara, Programas de Pós-Graduação, A. Gomes, É. H. Frederico
In cosmetology, although the use of natural products can be considered as a fancy, research related to the hair growth has been considered. Some synthetic products, as minoxidil and finasteride have been used to stimulate the hair. However, several important side effects have been reported with these drugs. Natural products are gaining popularity mainly due to, in general, their fewer side effects and better formulation strategies. Hair loss is a dermatologic disorder and urges the necessity of alternative treatments with hair growth promoting potential, as the medicinal plants. Among the medicinal plants used to treat the hair loss and to promote the hair growth, there is the Panax ginseng. The purpose of this study was to review the published researches concerning the use of Panax ginseng in investigations involving the hair growth using the PubMed database. Eight studies have reached the inclusion criteria to be analyzed. Considering the selected papers, there is a predominance of experimental procedures with the compound ginsenoside. The aim of the works was mainly related to investigation on the molecular and cellular mechanisms responsible for hair growth in presence of Panax ginseng or a compound related to this natural product. The number of publications in PubMed with the keyword Panax ginseng involving hair growth is about 0.43 %. The results indicate that Panax ginseng has stood out as a promising natural source with relevant effects in treatment of hair loss, despite the small number of publications selected involving the keywords “Panax ginseng” AND “hair loss”. Putting together the findings, it is concluded that the use of Panax ginseng and its chemical products could be an important strategy to manage the loss hair.
{"title":"Is There Scientific Evidence that Panax Promotes Hair Growth?","authors":"Frederico Ehff, G. Cas, R. Santos, Guedes-de-Aguiar Eo, G. Cr, C. R. Kütter, L. Machado-Rocha, P. Fg, A. Rosa, R. F. Neves, E. Moreira-Marconi, P. L. Souza, S. Paoli, Roberto Alcántara, Programas de Pós-Graduação, A. Gomes, É. H. Frederico","doi":"10.17140/tcoj-1-101","DOIUrl":"https://doi.org/10.17140/tcoj-1-101","url":null,"abstract":"In cosmetology, although the use of natural products can be considered as a fancy, research related to the hair growth has been considered. Some synthetic products, as minoxidil and finasteride have been used to stimulate the hair. However, several important side effects have been reported with these drugs. Natural products are gaining popularity mainly due to, in general, their fewer side effects and better formulation strategies. Hair loss is a dermatologic disorder and urges the necessity of alternative treatments with hair growth promoting potential, as the medicinal plants. Among the medicinal plants used to treat the hair loss and to promote the hair growth, there is the Panax ginseng. The purpose of this study was to review the published researches concerning the use of Panax ginseng in investigations involving the hair growth using the PubMed database. Eight studies have reached the inclusion criteria to be analyzed. Considering the selected papers, there is a predominance of experimental procedures with the compound ginsenoside. The aim of the works was mainly related to investigation on the molecular and cellular mechanisms responsible for hair growth in presence of Panax ginseng or a compound related to this natural product. The number of publications in PubMed with the keyword Panax ginseng involving hair growth is about 0.43 %. The results indicate that Panax ginseng has stood out as a promising natural source with relevant effects in treatment of hair loss, despite the small number of publications selected involving the keywords “Panax ginseng” AND “hair loss”. Putting together the findings, it is concluded that the use of Panax ginseng and its chemical products could be an important strategy to manage the loss hair.","PeriodicalId":189690,"journal":{"name":"Trichology and Cosmetology – Open Journal","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131832484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The process of de-epithelialization in reduction mammoplasty surgery increases the operation time. In addition, longer operation times are more apt to cause fatigue for the surgeon. Furthermore, it is always preferable to use the time in the operating theater as effectively as possible. Although the gold standard when performing de-epithelialization is with the use of a scalpel, there are some initiatives to accelerate the speed of the operation and decrease the blood loss during the operation.1-5 While the use of novel products has the potential to speed up the operation, their use may be accompanied by unexpected complications.
{"title":"A Simple Method for Breast De-epithelialization: The Monobloc Method","authors":"M. Keleş, Uğur Horoz, H. Cepni","doi":"10.17140/tcoj-1-104","DOIUrl":"https://doi.org/10.17140/tcoj-1-104","url":null,"abstract":"The process of de-epithelialization in reduction mammoplasty surgery increases the operation time. In addition, longer operation times are more apt to cause fatigue for the surgeon. Furthermore, it is always preferable to use the time in the operating theater as effectively as possible. Although the gold standard when performing de-epithelialization is with the use of a scalpel, there are some initiatives to accelerate the speed of the operation and decrease the blood loss during the operation.1-5 While the use of novel products has the potential to speed up the operation, their use may be accompanied by unexpected complications.","PeriodicalId":189690,"journal":{"name":"Trichology and Cosmetology – Open Journal","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134121872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Lucia, A. Carola, A. Tito, S. Buono, A. Langellotti, V. Fogliano, G. Colucci, F. Apone
The sebum has important protective functions for the skin, although its overproduction may lead to undesired aesthetic problems and even more serious skin diseases. Sebum overproduction is caused by the androgen hormone testosterone, which is regulated by the enzyme 5-α Reductase, and can be associated with an over-proliferation of parasitic microbes that cause serious infections linked to skin inflammatory reactions. From the extremophile microalga Galdieria sulphuraria, we obtained a water-soluble extract and we found that it was capable of inhibiting the enzyme 5-α Reductase, inducing the expression of the β-defensins, which represents the first defense response mechanism triggered by the skin cells to fight against undesired microbes, and stimulating the wound healing process in skin cell cultures. The microalga extract was finally employed in clinical tests on human volunteers and it was confirmed its capacity to regulate sebum production. The results suggested that the Galdieria extract had interesting potentialities as active ingredient in cosmetic and dermatological formulas, in particular in those addressed to oily and seborrheic skins.
{"title":"Galdieria sulphuraria Relieves Oily and Seborrheic Skin By Inhibiting the 5-α Reductase Expression in Skin Cells and Reducing Sebum Production In Vivo","authors":"A. Lucia, A. Carola, A. Tito, S. Buono, A. Langellotti, V. Fogliano, G. Colucci, F. Apone","doi":"10.17140/tcoj-1-103","DOIUrl":"https://doi.org/10.17140/tcoj-1-103","url":null,"abstract":"The sebum has important protective functions for the skin, although its overproduction may lead to undesired aesthetic problems and even more serious skin diseases. Sebum overproduction is caused by the androgen hormone testosterone, which is regulated by the enzyme 5-α Reductase, and can be associated with an over-proliferation of parasitic microbes that cause serious infections linked to skin inflammatory reactions. From the extremophile microalga Galdieria sulphuraria, we obtained a water-soluble extract and we found that it was capable of inhibiting the enzyme 5-α Reductase, inducing the expression of the β-defensins, which represents the first defense response mechanism triggered by the skin cells to fight against undesired microbes, and stimulating the wound healing process in skin cell cultures. The microalga extract was finally employed in clinical tests on human volunteers and it was confirmed its capacity to regulate sebum production. The results suggested that the Galdieria extract had interesting potentialities as active ingredient in cosmetic and dermatological formulas, in particular in those addressed to oily and seborrheic skins.","PeriodicalId":189690,"journal":{"name":"Trichology and Cosmetology – Open Journal","volume":"139 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132688050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the past, cost and effectiveness of formulation was the first aspect for formulators. Meanwhile, the world has changed as a result of the growing public sensibility for any kind of chemical in the products of daily use. Extensive changes in the worldwide regulatory context of cosmetics, increasing limitations in the choice of cosmetic ingredients and the desire of “educated” consumers for safe products, with the best possible dermatological, toxicological and environmental properties, force the cosmetic chemist to rethink about the choice for alternative ingredients and new methodologies of formulation, as well.
{"title":"Cosmetology: Past, Present and Future","authors":"Varvaresou Athanasia","doi":"10.17140/tcoj-1-e001","DOIUrl":"https://doi.org/10.17140/tcoj-1-e001","url":null,"abstract":"In the past, cost and effectiveness of formulation was the first aspect for formulators. Meanwhile, the world has changed as a result of the growing public sensibility for any kind of chemical in the products of daily use. Extensive changes in the worldwide regulatory context of cosmetics, increasing limitations in the choice of cosmetic ingredients and the desire of “educated” consumers for safe products, with the best possible dermatological, toxicological and environmental properties, force the cosmetic chemist to rethink about the choice for alternative ingredients and new methodologies of formulation, as well.","PeriodicalId":189690,"journal":{"name":"Trichology and Cosmetology – Open Journal","volume":"144 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124392958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：