Pub Date : 2022-06-30DOI: 10.20307/nps.2022.28.2.68
Hyun Jun Lee, H. Kim, Sang-Back Kim, Kyung-Jun Boo, Mae Ortiz Darlene, Val Sayson Leandro, Perez Custodio Raly James, J. Cheong, S. Kim, Mikyung Kim
{"title":"Standardized Extract (HemoHIM) Ameliorated High Intensity Exercise Induced Fatigue in Mice","authors":"Hyun Jun Lee, H. Kim, Sang-Back Kim, Kyung-Jun Boo, Mae Ortiz Darlene, Val Sayson Leandro, Perez Custodio Raly James, J. Cheong, S. Kim, Mikyung Kim","doi":"10.20307/nps.2022.28.2.68","DOIUrl":"https://doi.org/10.20307/nps.2022.28.2.68","url":null,"abstract":"","PeriodicalId":19080,"journal":{"name":"Natural product sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45402499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.20307/nps.2022.28.2.75
Chae-Won Kim, J. Ko, Do Hyeong Kim, D. Jin, S. Ko
{"title":"A Comparison of Phenolic Components in Cinnamon Medicines","authors":"Chae-Won Kim, J. Ko, Do Hyeong Kim, D. Jin, S. Ko","doi":"10.20307/nps.2022.28.2.75","DOIUrl":"https://doi.org/10.20307/nps.2022.28.2.75","url":null,"abstract":"","PeriodicalId":19080,"journal":{"name":"Natural product sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45567547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.20307/nps.2022.28.2.89
Hyojin Lee, K. Jang
{"title":"Effect of Puffing in the Extraction of Active Ingredients from the Roots of Paeonia lactiflora and Astragalus membranaceus","authors":"Hyojin Lee, K. Jang","doi":"10.20307/nps.2022.28.2.89","DOIUrl":"https://doi.org/10.20307/nps.2022.28.2.89","url":null,"abstract":"","PeriodicalId":19080,"journal":{"name":"Natural product sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41485831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.20307/nps.2022.28.2.80
Dan-dan Li, Y. Wang, Ju Zhiran, Eun-La Kim, Jongki Hong, Jee H Jung
{"title":"Anti-metastatic Effect of Natural Product-motivated Synthetic PPAR-γ Ligands","authors":"Dan-dan Li, Y. Wang, Ju Zhiran, Eun-La Kim, Jongki Hong, Jee H Jung","doi":"10.20307/nps.2022.28.2.80","DOIUrl":"https://doi.org/10.20307/nps.2022.28.2.80","url":null,"abstract":"","PeriodicalId":19080,"journal":{"name":"Natural product sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45578247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-31DOI: 10.20307/nps.2022.28.1.1
Y. Ha, Tae Hyun Lee, S. Lalita, H. Kim, Gyuri Moon, S. Kim, C. Kim
Two 2 H -1-benzopyran derivatives, methyl 8-hydroxy-2,2-dimethyl-2 H -1-benzopyran-5-carboxylate ( 1 ) and methyl 8-hydroxy-2,2-dimethyl-2 H -1-benzopyran-6-carboxylate ( 2 ), including a new compound ( 1 ) were isolated from the twigs of Chaenomeles sinensis . Their chemical structures were characterized based on analysis of NMR data including 1 H and 13 C, COSY, HSQC, and HMBC and HRMS data. The isolated compounds ( 1 and 2 ) were assessed for their anti-neuroinflammatory activity by measuring inhibition levels of nitric oxide (NO) production in lipopolysaccharide (LPS)-activated BV-2 cells and for their neurotrophic activity by the secretion of nerve growth factor (NGF) in C6 cells. Compounds 1 and 2 exhibited powerful anti-neuroinflammatory effects with IC 50 values of 17.14 and 19.30 μ M, respectively, without cell toxicity, and also showed moderate effects on the stimulation of NGF secretion levels with 113.15 ± 3.54 and 130.20 ± 8.03%, respectively. The biosynthetic pathway of 1 and 2 was proposed that they would be derived from a protocatechuic acid and an isoprenyl unit.
{"title":"Anti-inflammatory and Neurotrophic 2H-1-Benzopyran Derivatives of Chaenomeles sinensis","authors":"Y. Ha, Tae Hyun Lee, S. Lalita, H. Kim, Gyuri Moon, S. Kim, C. Kim","doi":"10.20307/nps.2022.28.1.1","DOIUrl":"https://doi.org/10.20307/nps.2022.28.1.1","url":null,"abstract":" Two 2 H -1-benzopyran derivatives, methyl 8-hydroxy-2,2-dimethyl-2 H -1-benzopyran-5-carboxylate ( 1 ) and methyl 8-hydroxy-2,2-dimethyl-2 H -1-benzopyran-6-carboxylate ( 2 ), including a new compound ( 1 ) were isolated from the twigs of Chaenomeles sinensis . Their chemical structures were characterized based on analysis of NMR data including 1 H and 13 C, COSY, HSQC, and HMBC and HRMS data. The isolated compounds ( 1 and 2 ) were assessed for their anti-neuroinflammatory activity by measuring inhibition levels of nitric oxide (NO) production in lipopolysaccharide (LPS)-activated BV-2 cells and for their neurotrophic activity by the secretion of nerve growth factor (NGF) in C6 cells. Compounds 1 and 2 exhibited powerful anti-neuroinflammatory effects with IC 50 values of 17.14 and 19.30 μ M, respectively, without cell toxicity, and also showed moderate effects on the stimulation of NGF secretion levels with 113.15 ± 3.54 and 130.20 ± 8.03%, respectively. The biosynthetic pathway of 1 and 2 was proposed that they would be derived from a protocatechuic acid and an isoprenyl unit.","PeriodicalId":19080,"journal":{"name":"Natural product sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44622534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-31DOI: 10.20307/nps.2022.28.1.27
Jungwon Choi, Juree Kim, Hak-Dong Lee, H. Cho, Adrianne Paje Leo, Hanna Shin, Sanghyun Lee
{"title":"Development of an Analytical Approach for the Utilization of Edible Tree Sprouts","authors":"Jungwon Choi, Juree Kim, Hak-Dong Lee, H. Cho, Adrianne Paje Leo, Hanna Shin, Sanghyun Lee","doi":"10.20307/nps.2022.28.1.27","DOIUrl":"https://doi.org/10.20307/nps.2022.28.1.27","url":null,"abstract":"","PeriodicalId":19080,"journal":{"name":"Natural product sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45931608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-31DOI: 10.20307/nps.2022.28.1.13
Hartati Sri, M. Megawati, Dwi Antika Lucia
{"title":"Parvidepsidone, a Novel Depsidone from the Barks of Garcinia parvifolia Miq.","authors":"Hartati Sri, M. Megawati, Dwi Antika Lucia","doi":"10.20307/nps.2022.28.1.13","DOIUrl":"https://doi.org/10.20307/nps.2022.28.1.13","url":null,"abstract":"","PeriodicalId":19080,"journal":{"name":"Natural product sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43854581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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