A. Zaboli, G. Turcato, B. Nucera, S. Sibilio, F. Rinaldi, Laura D’Acunto, P. Manganotti, R. Nardone, N. Pfeifer, F. Brigo
The Manchester Triage System (MTS) is one of the most widely used and studied triage systems in emergency departments (ED). MTS does not have a specific presentational flow chart for patients with transient global amnesia (TGA). The goal of this study was to determine the adequacy of priority code assignment for patients with TGA presenting at the ED and triaged using the MTS.
{"title":"Validity of the Manchester triage system in the prioritization of patients with transient global amnesia in the emergency department","authors":"A. Zaboli, G. Turcato, B. Nucera, S. Sibilio, F. Rinaldi, Laura D’Acunto, P. Manganotti, R. Nardone, N. Pfeifer, F. Brigo","doi":"10.1111/ncn3.12720","DOIUrl":"https://doi.org/10.1111/ncn3.12720","url":null,"abstract":"The Manchester Triage System (MTS) is one of the most widely used and studied triage systems in emergency departments (ED). MTS does not have a specific presentational flow chart for patients with transient global amnesia (TGA). The goal of this study was to determine the adequacy of priority code assignment for patients with TGA presenting at the ED and triaged using the MTS.","PeriodicalId":19154,"journal":{"name":"Neurology and Clinical Neuroscience","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44708498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Natsuko Togawa, Masahiro Mitsuhashi, H. Yamashita, S. Minamiguchi, Y. Arakawa, T. Ayaki, A. Kuzuya, A. Ikeda, Ryosuke Takahashi
H3K27M‐mutant diffuse midline glioma is a malignant glioma that was newly added to the World Health Organization classification in 2016. In diffuse midline glioma, the H3K27M‐mutant sometimes develops sub‐acutely and requires a differential diagnosis from encephalomyelitis. Here, we report a case of adult‐onset diffuse midline glioma that was diagnosed by immunostaining for histone H3K27M after death. The present case required a differential diagnosis of autoimmune cervical myelitis and brainstem encephalitis.
{"title":"A case of adult‐onset diffuse midline glioma diagnosed by histone H3K27M immunostaining after death, which required differentiation from brainstem encephalitis and myelitis","authors":"Natsuko Togawa, Masahiro Mitsuhashi, H. Yamashita, S. Minamiguchi, Y. Arakawa, T. Ayaki, A. Kuzuya, A. Ikeda, Ryosuke Takahashi","doi":"10.1111/ncn3.12718","DOIUrl":"https://doi.org/10.1111/ncn3.12718","url":null,"abstract":"H3K27M‐mutant diffuse midline glioma is a malignant glioma that was newly added to the World Health Organization classification in 2016. In diffuse midline glioma, the H3K27M‐mutant sometimes develops sub‐acutely and requires a differential diagnosis from encephalomyelitis. Here, we report a case of adult‐onset diffuse midline glioma that was diagnosed by immunostaining for histone H3K27M after death. The present case required a differential diagnosis of autoimmune cervical myelitis and brainstem encephalitis.","PeriodicalId":19154,"journal":{"name":"Neurology and Clinical Neuroscience","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45235057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A 48yearold male with a history of hypertension presented to the emergency department with acute onset leftsided weakness, dysarthria, and blood pressure of 196/113 mm Hg. Head computed tomography (CT) revealed a right basal ganglia and subarachnoid hemorrhage. (Figure 1A) Head CT angiogram showed a 2.9 mm aneurysm in the medial distal lenticulostriate artery (LSA) within the area of hematoma suggestive of aneurysm rupture. (Figure 1B– D). Aneurysms of LSA are a rare finding with an average diameter of 3.88 mm (ranging from 1– 19 mm) and are usually missed by CT angiogram.1,2 These aneurysms can be located either proximally near
{"title":"Computed tomography angiography evidence of distal lenticulostriate artery aneurysm","authors":"Riwaj Bhagat, Alexis Clay, Ava Bakhtyari","doi":"10.1111/ncn3.12717","DOIUrl":"https://doi.org/10.1111/ncn3.12717","url":null,"abstract":"A 48yearold male with a history of hypertension presented to the emergency department with acute onset leftsided weakness, dysarthria, and blood pressure of 196/113 mm Hg. Head computed tomography (CT) revealed a right basal ganglia and subarachnoid hemorrhage. (Figure 1A) Head CT angiogram showed a 2.9 mm aneurysm in the medial distal lenticulostriate artery (LSA) within the area of hematoma suggestive of aneurysm rupture. (Figure 1B– D). Aneurysms of LSA are a rare finding with an average diameter of 3.88 mm (ranging from 1– 19 mm) and are usually missed by CT angiogram.1,2 These aneurysms can be located either proximally near","PeriodicalId":19154,"journal":{"name":"Neurology and Clinical Neuroscience","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42540425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Takuma Maeda, M. Okawara, Manabu Osakabe, Hiroyuki Yamaguchi, Takahiro Maeda, S. Maeshima
Reports of stroke‐related catalepsy and other catatonia syndromes are rare. A 68‐year‐old man was admitted to a local hospital 10 days prior for heart failure. He subsequently developed multiple cerebral infarctions and was referred to our hospital for emergency care. He spontaneously opened his eyes but did not speak. He had hemiparesis on the right side. Diffusion‐weighted imaging revealed high‐intensity areas in the left frontal and parietal lobes and right cerebellar hemisphere. Rehabilitation therapy was initiated in the acute stage. When he was instructed to raise his left upper limb 90°, he maintained the posture for more than 5 min. We hypothesized that catatonia syndromes, including catalepsy, were caused by damage to the orbitofrontal, premotor, supplementary motor cortices, and basal forebrain. These abnormalities disappeared after 4 months. Catalepsy may also be observed in organic central nervous system diseases, such as stroke, and should be considered in stroke care.
{"title":"A case of catalepsy after multiple cerebral infarctions","authors":"Takuma Maeda, M. Okawara, Manabu Osakabe, Hiroyuki Yamaguchi, Takahiro Maeda, S. Maeshima","doi":"10.1111/ncn3.12716","DOIUrl":"https://doi.org/10.1111/ncn3.12716","url":null,"abstract":"Reports of stroke‐related catalepsy and other catatonia syndromes are rare. A 68‐year‐old man was admitted to a local hospital 10 days prior for heart failure. He subsequently developed multiple cerebral infarctions and was referred to our hospital for emergency care. He spontaneously opened his eyes but did not speak. He had hemiparesis on the right side. Diffusion‐weighted imaging revealed high‐intensity areas in the left frontal and parietal lobes and right cerebellar hemisphere. Rehabilitation therapy was initiated in the acute stage. When he was instructed to raise his left upper limb 90°, he maintained the posture for more than 5 min. We hypothesized that catatonia syndromes, including catalepsy, were caused by damage to the orbitofrontal, premotor, supplementary motor cortices, and basal forebrain. These abnormalities disappeared after 4 months. Catalepsy may also be observed in organic central nervous system diseases, such as stroke, and should be considered in stroke care.","PeriodicalId":19154,"journal":{"name":"Neurology and Clinical Neuroscience","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43814582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Yoshizaki, Shinobu Minatani, Hiroto Namba, Akitoshi Takeda, J. Kawabe, Hideko Mizuta, Yasuhiro Wada, A. Mawatari, Yasuyoshi Watanabe, H. Shimada, Makoto Higuchi, Y. Itoh
Heterogeneity in Alzheimer's disease (AD) has been reported on the basis of clinical, neuropathological, and neuroimaging data. However, most of the indices, including cerebral atrophy evaluated using magnetic resonance imaging and amyloid β (Aβ) accumulation detected using positron emission tomography (PET), lack sensitivity, and specificity for categorization.
{"title":"Tau accumulates differently in four subtypes of Alzheimer's disease","authors":"T. Yoshizaki, Shinobu Minatani, Hiroto Namba, Akitoshi Takeda, J. Kawabe, Hideko Mizuta, Yasuhiro Wada, A. Mawatari, Yasuyoshi Watanabe, H. Shimada, Makoto Higuchi, Y. Itoh","doi":"10.1111/ncn3.12715","DOIUrl":"https://doi.org/10.1111/ncn3.12715","url":null,"abstract":"Heterogeneity in Alzheimer's disease (AD) has been reported on the basis of clinical, neuropathological, and neuroimaging data. However, most of the indices, including cerebral atrophy evaluated using magnetic resonance imaging and amyloid β (Aβ) accumulation detected using positron emission tomography (PET), lack sensitivity, and specificity for categorization.","PeriodicalId":19154,"journal":{"name":"Neurology and Clinical Neuroscience","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41264771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Montalvan, Walter R Duarte-Celada, T. Bueso, Jeannie Lee, K. Rivas, Gabriel Neves, Yuanyuan Tan, Jannatul Ferdous
Isolated cortical venous thrombosis (ICVT) is an uncommon subtype of cerebral venous thrombosis that only affects the cortical veins on the cerebral convexities. Its clinical presentation is variable and may mimic other neurological conditions.
{"title":"Isolated cortical venous thrombosis: A systematic review","authors":"V. Montalvan, Walter R Duarte-Celada, T. Bueso, Jeannie Lee, K. Rivas, Gabriel Neves, Yuanyuan Tan, Jannatul Ferdous","doi":"10.1111/ncn3.12714","DOIUrl":"https://doi.org/10.1111/ncn3.12714","url":null,"abstract":"Isolated cortical venous thrombosis (ICVT) is an uncommon subtype of cerebral venous thrombosis that only affects the cortical veins on the cerebral convexities. Its clinical presentation is variable and may mimic other neurological conditions.","PeriodicalId":19154,"journal":{"name":"Neurology and Clinical Neuroscience","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47005734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Ueno, Narumi Ohno, Miharuka Yokosaki, Tatsuya Ohtani, Kazuki Kimoto, Chika Matsuoka, Mayumi Giga, T. Kono, D. Agari, E. Nomura
A 74yearold woman presented with a 1year history of progressive weakness and pain in the right leg. Despite L4L5 laminoplasty performed at another hospital 2 months before admission, her clinical manifestations had deteriorated and she was referred and admitted to our hospital. Diffusionweighted wholebody imaging with background body signal suppression (DWIBS) showed diffusion restrictions in the L2 and L3 nerve roots, femoral nerve, and uterus (Figure 1A). Uterine needle biopsy revealed diffuse large Bcell lymphoma. These findings indicated a diagnosis of secondary neurolymphomatosis. Wholebody 18Ffluorodeoxyglucosepositron
{"title":"Diagnostic usefulness of whole‐body diffusion‐weighted imaging in neurolymphomatosis without FDG uptake","authors":"H. Ueno, Narumi Ohno, Miharuka Yokosaki, Tatsuya Ohtani, Kazuki Kimoto, Chika Matsuoka, Mayumi Giga, T. Kono, D. Agari, E. Nomura","doi":"10.1111/ncn3.12713","DOIUrl":"https://doi.org/10.1111/ncn3.12713","url":null,"abstract":"A 74yearold woman presented with a 1year history of progressive weakness and pain in the right leg. Despite L4L5 laminoplasty performed at another hospital 2 months before admission, her clinical manifestations had deteriorated and she was referred and admitted to our hospital. Diffusionweighted wholebody imaging with background body signal suppression (DWIBS) showed diffusion restrictions in the L2 and L3 nerve roots, femoral nerve, and uterus (Figure 1A). Uterine needle biopsy revealed diffuse large Bcell lymphoma. These findings indicated a diagnosis of secondary neurolymphomatosis. Wholebody 18Ffluorodeoxyglucosepositron","PeriodicalId":19154,"journal":{"name":"Neurology and Clinical Neuroscience","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47883492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Keisuke Mizutani, T. Oguri, K. Sakurai, H. Yuasa, K. Takada
Bilateral medial medullary infarction (MMI) is a rare form of ischemic stroke, mainly caused by vertebral artery atherosclerosis or small penetrating artery disease. We report a case of bilateral MMI due to varicella‐zoster virus (VZV) vasculopathy. An 81‐year‐old man presented with altered consciousness and right hemiplegia during disseminated herpes zoster. Polymerase chain reaction analysis of his cerebrospinal fluid detected positive VZV‐DNA, and magnetic resonance imaging revealed ischemic infarction localized to the ventral part of the bilateral medial medulla and enhancement of the left vertebral artery. After initiating intravenous acyclovir administration, his consciousness, skin rashes, and general condition improved gradually, whereas pyramidal symptoms deteriorated into quadriplegia. This case demonstrates that VZV vasculopathy may cause bilateral MMI.
{"title":"Bilateral medial medullary infarction due to varicella‐zoster virus vasculopathy: A case report","authors":"Keisuke Mizutani, T. Oguri, K. Sakurai, H. Yuasa, K. Takada","doi":"10.1111/ncn3.12712","DOIUrl":"https://doi.org/10.1111/ncn3.12712","url":null,"abstract":"Bilateral medial medullary infarction (MMI) is a rare form of ischemic stroke, mainly caused by vertebral artery atherosclerosis or small penetrating artery disease. We report a case of bilateral MMI due to varicella‐zoster virus (VZV) vasculopathy. An 81‐year‐old man presented with altered consciousness and right hemiplegia during disseminated herpes zoster. Polymerase chain reaction analysis of his cerebrospinal fluid detected positive VZV‐DNA, and magnetic resonance imaging revealed ischemic infarction localized to the ventral part of the bilateral medial medulla and enhancement of the left vertebral artery. After initiating intravenous acyclovir administration, his consciousness, skin rashes, and general condition improved gradually, whereas pyramidal symptoms deteriorated into quadriplegia. This case demonstrates that VZV vasculopathy may cause bilateral MMI.","PeriodicalId":19154,"journal":{"name":"Neurology and Clinical Neuroscience","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42428917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Asuka Suzuki, Yuka Nakaya, Koji Hayashi, M. Ueda, Rei Asano, Yudai Tanaka, H. Hayashi, Toyoaki Miura, K. Hayashi, K. Fujita, Kaori Kawabata, Yasutaka Kobayashi, Mamiko Sato
{"title":"Bálint syndrome by cerebral septic embolism","authors":"Asuka Suzuki, Yuka Nakaya, Koji Hayashi, M. Ueda, Rei Asano, Yudai Tanaka, H. Hayashi, Toyoaki Miura, K. Hayashi, K. Fujita, Kaori Kawabata, Yasutaka Kobayashi, Mamiko Sato","doi":"10.1111/ncn3.12711","DOIUrl":"https://doi.org/10.1111/ncn3.12711","url":null,"abstract":"","PeriodicalId":19154,"journal":{"name":"Neurology and Clinical Neuroscience","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48569429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Shiraishi, T. Kamo, R. Kumazawa, N. Sasaki, K. Isahaya, H. Akiyama, Y. Furusawa, Reiko Onodera, Jovelle L Fernandez, Masaru Otsuka, Y. Yamano
As motor symptoms of Parkinson's disease (PD) progress, visits to medical clinics for patients and caregivers become burdensome.
随着帕金森病（PD）运动症状的发展，患者和护理人员去诊所就诊变得繁重。
{"title":"A multicenter, prospective, observational study to assess the satisfaction of an integrated digital platform of online medical care and remote patient monitoring in Parkinson's disease","authors":"M. Shiraishi, T. Kamo, R. Kumazawa, N. Sasaki, K. Isahaya, H. Akiyama, Y. Furusawa, Reiko Onodera, Jovelle L Fernandez, Masaru Otsuka, Y. Yamano","doi":"10.1111/ncn3.12709","DOIUrl":"https://doi.org/10.1111/ncn3.12709","url":null,"abstract":"As motor symptoms of Parkinson's disease (PD) progress, visits to medical clinics for patients and caregivers become burdensome.","PeriodicalId":19154,"journal":{"name":"Neurology and Clinical Neuroscience","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41475217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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