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Complementary feeding practices and nutritional status of young children in a community in Sokoto 索科托一个社区幼儿的补充喂养做法和营养状况
Pub Date : 2020-08-28 DOI: 10.4314/njp.v47i4.5
Yusuf T Jibrin, C. –BY
Background: Complementary feeding is the cornerstone of child’s nutrition. Most malnourished children had their predicament originating from  the period of transition from breastfeeding to family diet. Objectives: To determine the complementary feeding practices and nutritional status of young children in Gwiwa community. Materials and  Methods: This cross-sectional study was carried out in Gwiwa community, Wammakko LGA, Sokoto State between January and June,  2018. Three hundred and ten mothers with their children aged 6 –36 months were interviewed using structured interviewer - administered questionnaire and the children’s nutritional status was assessed using WHO classification of malnutrition. Data was analysed using SPSS version22.0.A p-value ≤0.05 was taken as significan. Results: One hundred and forty (45.2%) respondents were aged  15 – 24years and 168(54.2%) were of low socio-economic class. There were 190  males and 120 females with 66 (21.3%) children exclusively bre as t - fed for 6months. The mean age of cessation of breast feeding was 17.8 ±3.6 months. One hundred and sixty-nine (54.5%) children commenced complementary feeding at 6-8month of age with the mean age of 5.7(±2.6) months. One hundred and eighty-four (59.4%) used plain pap with 41.2% fed more than 3 times per day. Eighty-two (26.5%), 56(18.1%) and 76 (24.5%) children were underweight, wasted and stunted respectively. Conclusion: The complementary feeding practices were suboptimal in this community and might explain the poor nutritional status of their under- fives. Efforts should be geared towards optimal complementary feeding practices in this community. Key words: Complementary, Feeding, Practice, Nutritional, Status, Under-5.
背景:辅食喂养是儿童营养的基石。大多数营养不良儿童的困境源于从母乳喂养到家庭饮食的过渡时期。目的:了解Gwiwa社区幼儿的补充喂养方式和营养状况。材料和方法:本横断面研究于2018年1月至6月在索科托州Wammakko LGA的Gwiwa社区进行。采用结构化访谈问卷对310名母亲及其6 - 36个月大的孩子进行了访谈,并采用世卫组织营养不良分类对儿童的营养状况进行了评估。数据采用SPSS version22.0进行分析。p值≤0.05为显著性。结果:15 ~ 24岁受访者140人(45.2%),低社会经济阶层168人(54.2%)。男190例,女120例,纯喂养6个月儿66例(21.3%)。停止母乳喂养的平均年龄为17.8±3.6个月。169名(54.5%)儿童在6-8月龄开始补充喂养,平均年龄为5.7(±2.6)个月。184例(59.4%)使用普通pap, 41.2%每天喂食3次以上。体重不足82例(26.5%),消瘦56例(18.1%),发育不良76例(24.5%)。结论:该社区的补充喂养方式不理想,可能是造成该社区5岁以下儿童营养状况不佳的原因。应努力在该社区采用最佳补充喂养方法。关键词:辅食,喂养,实践,营养,现状,5岁以下儿童
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引用次数: 5
Precocious puberty in a 24 month old Nigerian girl: case report 1例24个月大尼日利亚女童性早熟:病例报告
Pub Date : 2020-08-28 DOI: 10.4314/njp.v47i4.10
I. Oluwayemi, A. Afolabi, E. Adeniji, T. Ayeni
Precocious puberty refers to the appearance of signs of puberty at an earlier age than is considered normal. It occurs ten times more commonly in  girls than in boys. The overall incidence ranged from 1/5000 to 1/10,000 children. The cause is idiopathic in 90% of cases of female precocious  puberty. We present BA a 24 month old female toddler who presented with one year history of progressive breast development and 6 month history of pubic hair growth. There was associated increasing weight, height and vaginal secretion. There was no similar occurrence in the family. Mother attained menarche at 14 years of age. Essential finding at presentation revealed a toddler who is heavy and tall for age with a weight of 17kg (>95th percentile for age and sex), height of 90.5cm (90th percentile for age and sex), Occipito-frontal circumference of 49cm (normal). Her sexual maturityrating was Tanner stage 3 for breasts and stage 2 for pubic hair. An assessment of precocious puberty was made. Her investigation result showed an advanced bone age of 5 years; elevated serum gonadotrophins in the pubertal range; and essentially normal cranial CT. Abdomino-pelvic USS showed an enlarged uterus for age, and a dominant right follicle with internal echo measuring 17.1mm X 15.2mm. Parents were counseled on the need for treatment to arrest the progression of precocious puberty but yet to respond because of financial constraint after 2 years of diagnosis. Female precocious puberty is ten times more common than male precocious puberty. The aetiology is idiopathic in 90% of cases and It is amenable to treatment. Integration of the investigation and treatment of childhood endocrine disorders into the National Health Insurance scheme will be a great panacea to the challenge of prompt management in developing countries. Keywords: Precocious, puberty, 24 months old, female, idiopathic, poverty, Nigeria
性早熟是指比正常年龄更早出现青春期迹象。女孩的发病率是男孩的十倍。总体发病率从1/5000到1/ 10000不等。在90%的女性性早熟病例中,原因是特发性的。我们报告一名24个月大的女婴,她表现出一年的乳房进行性发育史和6个月的阴毛生长史。与体重、身高和阴道分泌物增加有关。在这个家庭中没有类似的事情发生。母亲14岁时月经初潮。介绍时的基本发现显示,幼儿体重17kg(年龄和性别的第95百分位数),身高90.5cm(年龄和性别的第90百分位数),枕额围49cm(正常)。她的性成熟等级是坦纳3级,乳房是3级,阴毛是2级。对性早熟进行了评估。调查结果显示其骨龄提前5年;青春期范围血清促性腺激素升高;基本上是正常的头颅CT。腹部盆腔超声示子宫年龄增大,右侧优势卵泡,内回声17.1mm X 15.2mm。父母被告知需要治疗以阻止性早熟的进展,但在诊断两年后由于经济拮据而尚未作出反应。女性性早熟的发生率是男性性早熟的十倍。病因是特发性在90%的情况下,它是可以治疗的。将儿童内分泌失调的调查和治疗纳入国家健康保险计划,将是解决发展中国家及时管理挑战的灵丹妙药。关键词:性早熟,青春期,24个月大,女性,特发性,贫困,尼日利亚
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引用次数: 0
Barriers and impact of disclosure of HIV status to children at the National Hospital, Abuja Nigeria 尼日利亚阿布贾国家医院向儿童披露艾滋病毒状况的障碍和影响
Pub Date : 2020-08-28 DOI: 10.4314/njp.v47i4.2
M. Mukhtar-Yola, M. Kuczawski
Background: HIV infected children survive to adolescence because of anti retroviral therapy, however, only a small proportion know their diagnosis.Disclosure is critical to long-term disease management, yet little is known about if, how, and when disclosure takes place and the barriers associated with it, and its impact on children in resourcelimited settings. Objective: This study set out to determine the process of and barriers to HIV disclosure in children as well as the immediate impact of this on children and their caregivers. Methods: A cross-sectional study was done June-July 2016 using  a structured questionnaire, convenience sampling and quantitative methods at the infectious disease clinics of National Hospital Abuja. A sample of 164 caregivers of HIV positive children aged 5 to 16 years receiving antiretroviral therapy for at least one year were enrolled. Results: Prevalence of  full disclosure was 24.5%, partial 22.7% with overall prevalence of 47.2%. Main barrier to disclosure was child’s age and fear of informing others. The impact of disclosure on caregivers was relief in 45.5% but emotional and difficult for others. Immediate reactions by children were sadness;  tearfulness and worry in 28.6%, some showed no reaction while others even expressed relief. On a longer term, disclosure had several effects. Main predictors of disclosure on regression were the child’s age and caregiver’s opinion on disclosure. Conclusion: The prevalence of full disclosure is low and several barriers affect disclosure. Caregiver’s and HCWs need empowerment and support with culturally appropriate skills and platforms to  deal with the barriers, process and impact of disclosure.
背景:由于抗逆转录病毒治疗,感染艾滋病毒的儿童存活到青春期,然而,只有一小部分人知道他们的诊断结果。信息披露对疾病的长期管理至关重要,但人们对信息披露是否、如何以及何时发生以及与之相关的障碍以及在资源有限的环境中信息披露对儿童的影响知之甚少。目的:本研究旨在确定儿童艾滋病毒披露的过程和障碍,以及这对儿童及其照顾者的直接影响。方法:2016年6月至7月在阿布贾国家医院传染病诊所采用结构化问卷、方便抽样和定量方法进行横断面研究。164名5至16岁艾滋病毒阳性儿童的护理人员接受了至少一年的抗逆转录病毒治疗。结果:完全披露率为24.5%,部分披露率为22.7%,总体披露率为47.2%。披露的主要障碍是孩子的年龄和对告知他人的恐惧。45.5%的人对照顾者的影响是缓解,但对其他人的影响是情绪和困难。孩子们的第一反应是悲伤;28.6%的人流泪和担心,一些人没有反应,而另一些人甚至表示宽慰。从长期来看,信息披露有几个影响。儿童的年龄和照顾者对信息披露的看法是信息披露的主要预测因子。结论:充分披露的比例较低,存在一些障碍影响披露。护理人员和卫生保健工作者需要在文化上适当的技能和平台上获得授权和支持,以应对披露的障碍、过程和影响。
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引用次数: 2
Pyramidal cell morphology and cell death in the hippocampus of adult mice with experimentally induced hydrocephalus 实验性脑积水成年小鼠海马锥体细胞形态及细胞死亡
Pub Date : 2020-08-28 DOI: 10.4314/njp.v47i4.1
M. Shokunbi, F. Olopade, O. Femi-Akinlosotu, E. O. Ajiboye
Background: Hippocampus is a neural structure in the temporal lobe that plays a crucial role in learning and memory. Cognitive impairment with learning disabilities is a common feature in hydrocephalus and is more prominent in adult-onset hydrocephalus. The aim of this study is to describethe morphological alterations in the pyramidal cells of the hippocampus of adult hydrocephalic mice. Method: Hydrocephalus was induced in adult albino mice by intra-cisternal injection of kaolin suspension (250 mg/ml in sterile water). They were  sacrificed 7, 14 and 21 days post-induction. Morphological analysis was carried out on hematoxylin and eosinstained coronal sections of the  hippocampus: the pyramidal neurons (normal and pyknotic) in the CA1 and CA3 subregions were counted and the pyknotic index (PI) was  calculated. The somatic and dendritic features of Golgistained pyramidal neurons were examined by light microscopy in both hydrocephalic and control mice. Result: The PI was significantly greater in the CA1 region of the hippocampus in the hydrocephalic groups compared to the agematched controls. The dendritic processes of pyramidal neurons in the CA1 region were fewer with shorter terminal branches in the hydrocephalic mice than in  controls; this was pronounced at 7 days post-induction. In the CA3 region, there was no difference in dendritic arborization between hydrocephalic and control mice. Conclusion: Acute adult-onset hydrocephalus was associated with increased pyknosis and reduced dendritic arborization in hippocampal pyramidal cells in the CA1 but not CA3 region. Keywords: Hippocampal pyramidal cell, Hydrocephalus, Pyknotic index, Golgi stain
背景:海马是颞叶中的一个神经结构,在学习和记忆中起着至关重要的作用。认知障碍伴学习障碍是脑积水的共同特征,在成人发病的脑积水中更为突出。本研究的目的是描述成年脑积水小鼠海马锥体细胞的形态学改变。方法:用高岭土悬浮液(无菌水250 mg/ml)灌胃诱导成年白化病小鼠脑积水。分别于诱导后7、14、21天处死。对苏木精染色和伊红染色海马冠状面切片进行形态学分析:计数CA1和CA3亚区锥体神经元(正常和收缩),计算收缩指数(PI)。光镜下观察了脑积水小鼠和对照组高尔基染色锥体神经元的体细胞和树突特征。结果:脑积水组海马CA1区PI明显高于对照组。脑积水小鼠CA1区锥体神经元树突突少于对照组,末端分支较短;这在诱导后7天明显。在CA3区,脑积水小鼠和对照小鼠的树突状树突无差异。结论:急性成人脑积水与CA1区而非CA3区海马锥体细胞固缩增加和树突状树突减少有关。关键词:海马锥体细胞,脑积水,收缩指数,高尔基染色
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引用次数: 2
Immunovirological treatment outcomes after 2 years of antiretroviral therapy in children living with the human immune deficiency virus in Lagos Nigeria 尼日利亚拉各斯感染人类免疫缺陷病毒的儿童接受2年抗逆转录病毒治疗后的免疫病毒学治疗结果
Pub Date : 2020-08-28 DOI: 10.4314/njp.v47i4.7
O. Nwaiwu, A. Akindele, A. Akanmu, O. Adeyemi
Background/objective: The World Health Organization (WHO) recommends routine assessment of antiretroviral treatment outcomes to detect  treatment failure early and prevent the development of drug resistance. The aim of this study was to describe treatment outcomes of antiretroviral therapy (ART) over 2 years in children living with the human immune deficiency virus enrolled in the paediatric HIV clinic at the Lagos UniversityTeaching Hospital (LUTH).Materials and methods: This was a retrospective study of antiretroviral treatment outcomes in 278 children receiving antiretroviral therapy at the paediatric HIV clinic of LUTH. Demographic, clinical and laboratory data were retrospectively collected from clinical records of pediatric patientswho received antiretroviral therapy for 2 years ( from November 2015 to December 2017) . Virological failure was defined as viral load > 400  copies/ml and immunological failure was defined as a CD4 count 5000  copies/ml), poor adherence (<95%) and low baseline CD4 counts (101-249 cells/mn3) were significantly associated with virological failure, while low baseline CD4 counts (<350 cells/mn3) and poor adherence (<95%) were significantly associated with immunologic failure.Conclusion: The treatment outcomes observed in this study are similar to those reported in earlier studies. At 1 and 2 years of antiretroviral therapy , there was immune restoration however 101 (36%) and 87 (31%) respectively had virological failure despite good adherence to therapy and good Immunological restoration. This calls for early initiation and switch to second and third line drugs . Key words: Human immunodeficiency virus (HIV), zidovudine, lamivudine, nevirapine, virological blips, immunovirological discordance , children, Nigeria.
背景/目的:世界卫生组织(世卫组织)建议对抗逆转录病毒治疗结果进行常规评估,以便及早发现治疗失败并预防耐药性的产生。本研究的目的是描述在拉各斯大学教学医院(LUTH)儿科艾滋病毒诊所登记的感染人类免疫缺陷病毒的儿童2年以上抗逆转录病毒治疗(ART)的治疗结果。材料和方法:这是一项回顾性研究,在LUTH儿科HIV诊所接受抗逆转录病毒治疗的278名儿童的抗逆转录病毒治疗结果。回顾性收集接受抗逆转录病毒治疗2年(2015年11月至2017年12月)的儿科患者的临床记录中的人口统计学、临床和实验室数据。病毒学失败定义为病毒载量> 400拷贝/ml,免疫失败定义为CD4计数5000拷贝/ml),粘附性差(<95%)和低基线CD4计数(101-249细胞/mn3)与病毒学失败显著相关,而低基线CD4计数(<350细胞/mn3)和粘附性差(<95%)与免疫失败显著相关。结论:本研究观察到的治疗结果与早期研究报道的结果相似。在抗逆转录病毒治疗1年和2年时,尽管有良好的治疗依从性和良好的免疫恢复,但有101例(36%)和87例(31%)分别出现病毒学失败。这就需要尽早开始使用二线和三线药物。关键词:人类免疫缺陷病毒(HIV),齐多夫定,拉米夫定,奈韦拉平,病毒学突变,免疫病毒学不一致,儿童,尼日利亚
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引用次数: 0
Childhood acute glomerulonephritis in Ibadan Nigeria 尼日利亚伊巴丹的儿童急性肾小球肾炎
Pub Date : 2020-08-28 DOI: 10.4314/njp.v47i4.8
A. Asinobi, A. Ademola, A. Nwankwo
Background: Acute glomerulonephritis (AGN) is an important cause of mortality and morbidity in children in developing countries while its  incidence has declined in the developed world. This study was to document its present impact in our setting.Aim: To evaluate the sociodemographic features and clinical outcomes in children hospitalized for AGN in the Paediatric Nephrology Unit of the University College Hospital, Ibadan.Subjects and Methods: This was a descriptive analytical study of children aged 2 to 14 years admitted with AGN between 2007 and 2019. Their sociodemographic data, clinical features, complications and outcome were analysed.Results: AGN accounted for 116 (8.9%) of new renal cases admitted over the period. Seventy-four (63.8%) were male, mean age (SD) was 8.2 (3.3) years and peak age incidence between 5 and 9 years. Average annual hospital incidence rose from 4-5 new cases to 8-9 new cases/annum with an upsurge to 17 cases in 2019. Highest yearly monthly incidence was between June and December. Forty -five out of 50 (90%) evaluated subjects were in the middle/ low socioeconomic classes. Stage 2 hypertension occurred in 30/50 (60%) with hypertensive crises in 24%. RPGN occurred in 6/50 (12%) of cases accounting for 5 of the 8 dialysed patients and 4 of the 5 deaths. The case fatality rate was 4.3%.Conclusion: The study showed a progressive increase in the hospital incidence of AGN.RPGN was a major risk factor for death in children with AGN and therefore requires a high index of suspicion and an appropriate early intervention. Key words: Childhood, Acute Glomerulonephritis (AGN), Postinfectious AGN, Rapidly progressive glomerulonephritis (RPGN), Hypertensive crises,  Outcome
背景:急性肾小球肾炎(AGN)是发展中国家儿童死亡率和发病率的重要原因,而其发病率在发达国家有所下降。这项研究是为了记录它在我们的环境中目前的影响。目的:评价伊巴丹大学学院医院儿科肾脏病科因AGN住院儿童的社会人口学特征和临床结局。研究对象和方法:这是一项描述性分析研究,研究对象为2007年至2019年收治的2至14岁AGN儿童。分析患者的社会人口学资料、临床特征、并发症及转归。结果:AGN占同期新肾病例116例(8.9%)。男性74例(63.8%),平均年龄8.2(3.3)岁,发病高峰年龄在5 ~ 9岁。医院年平均新增病例从4-5例上升到8-9例,2019年上升到17例。每年6月至12月发病率最高。50名被评估的受试者中有45名(90%)属于中低社会经济阶层。2期高血压发生率为30/50(60%),高血压危象发生率为24%。6/50(12%)的病例发生RPGN,占8例透析患者中的5例和5例死亡中的4例。病死率为4.3%。结论:本研究显示AGN在医院的发病率呈进行性上升趋势。RPGN是患有AGN的儿童死亡的主要危险因素,因此需要高度怀疑和适当的早期干预。关键词:儿童;急性肾小球肾炎(AGN);感染后肾小球肾炎(AGN)
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引用次数: 1
Body mass index and blood pressure correlate in nursery school children in Port Harcourt, Nigeria 尼日利亚哈科特港幼儿园儿童的体重指数和血压相关
Pub Date : 2020-08-28 DOI: 10.4314/njp.v47i4.6
P. Tabansi, K. Onyemkpa
Introduction: Blood pressure (BP) is a vital indicator of health in  children and adults. The relationship between body mass index (BMI) and BP is  well established in children; and BMI has been shown to maintain an independent relationship with BP even after controlling for many other variables that characterize individuals. High BMI significantly increases the risk of hypertension. Epidemiological studies in various countries have been conducted to determine the relationship between BP and BMI in children; similar comparative studies are lacking in Nigeria, thus necessitating this study.Aim: To determine the relationship between BMI and BP in nursery pupils in Port Harcourt.Methods: Multi-staged sampling technique was used to select 710 nursery pupils from 13 schools. Biodata was obtained using a selfadministered(parent) questionnaire. Height and weight measurement were taken, and BMI calculated. BP was measured using a mercury sphygmomanometer; and relevant data analysis done.Result: There were 710 pupils 365 (51.4%) males and 345(48.6%) females. Mean systolic BP was 93.2 ± 10.6mmHg (70–130 mmHg); while mean  diastolic BP was 58.8 ± 8.0mmHg(40 – 88.7 mmHg). Mean BMI was 15.0 ± 1.8 kg/m2(9.1 - 25.5 kg/m2). There is a positive linear relationship betweensystolic and diastolic BP and BMI (correlation coefficient r = 0.03). Obese pupils had significantly higher BP rates (25%) (X2= 15.35, p =0.002). BMI and height were significant predictors of diastolic BP (p<0.001).Conclusion: There is a positive correlation between BMI and BP; and high BMI is an important predictor of high BP in nursery pupils in Nigeria. Keywords: Blood Pressure, BMI, Nursery pupils, Nigeria
血压(BP)是儿童和成人健康的重要指标。体重指数(BMI)与血压之间的关系在儿童中得到了很好的确立;BMI与BP保持独立的关系,即使在控制了许多其他个体特征变量之后。体重指数高会显著增加患高血压的风险。各国开展了流行病学研究,以确定儿童血压和BMI之间的关系;尼日利亚缺乏类似的比较研究,因此有必要进行这项研究。目的:探讨哈考特港幼儿园儿童体重指数与血压的关系。方法:采用多阶段抽样方法,抽取13所学校710名幼儿园在校生。生物数据通过自我管理(家长)问卷获得。测量身高、体重,计算BMI。用水银血压计测量血压;并对相关数据进行了分析。结果:学生710名,男生365名(51.4%),女生345名(48.6%)。平均收缩压93.2±10.6mmHg (70 ~ 130 mmHg);平均舒张压58.8±8.0mmHg(40 ~ 88.7 mmHg)。平均BMI为15.0±1.8 kg/m2(9.1 ~ 25.5 kg/m2)。收缩压、舒张压与BMI呈线性正相关(相关系数r = 0.03)。肥胖学生的血压发生率明显高于肥胖学生(25%)(X2= 15.35, p =0.002)。BMI和身高是舒张压的显著预测因子(p<0.001)。结论:BMI与BP呈正相关;高BMI是尼日利亚幼儿园儿童血压升高的重要预测指标。关键词:血压,BMI,幼儿园,尼日利亚
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引用次数: 0
Complications of pneumonia and its associated factors in a pediatric population in Osogbo, Nigeria 尼日利亚奥索博儿科人群肺炎并发症及其相关因素
Pub Date : 2020-08-28 DOI: 10.4314/njp.v47i4.4
AO Odeyemi, AO Oyedeji, Adebami OJ Odeyemi, C. –BY
Introduction: Pneumonia is one of the leading causes of morbidity and  mortality in underfive children. Nigeria still has a high burden of  child death due to pneumonia. Many of these deaths result from the development of complications. This study was done to determine the pattern of pneumonia complications and its associated factors amongst underfive children with pneumonia. Methods: It was a hospital-based cross-sectional observational study involving 129 children aged 1 - 60 months with a diagnosis of pneumonia. The participants were recruited over a nine-month period. Clinical signs were recorded, and a confirmatory chest radiograph was obtained within 24hours of admission. Result: Of the129 subjects studied, 70 (54.3%) had complications. Children less than 24 months had a higher frequency of complications at  presentation. Heart failure and anemia occurred more commonly. Other complications were pleural effusion, empyema, pneumatocele and  pneumothorax. More than half (57.1%) of those with complication were hypoxaemic at presentation. Complicated pneumonia was significantly  associated with prolonged hospital stay and risk of mortality. Conclusion: Complication is common among children hospitalized for pneumonia in Osogbo. Heart failure was the most common complication. Presence of pneumonia complications and hypoxaemia are important contributors to mortality in this environment. Keywords: Pneumonia, complication, under-fives, Nigeria.
肺炎是五岁以下儿童发病和死亡的主要原因之一。尼日利亚因肺炎造成的儿童死亡负担仍然很高。其中许多死亡是由于并发症的发展造成的。本研究旨在确定五岁以下儿童肺炎并发症的模式及其相关因素。方法:这是一项以医院为基础的横断面观察性研究,涉及129名年龄在1 - 60个月的诊断为肺炎的儿童。参与者是在9个月的时间里被招募的。记录临床症状,并在入院24小时内进行胸片检查。结果:129例患者中,70例(54.3%)出现并发症。小于24个月的儿童出现并发症的频率更高。心力衰竭和贫血更为常见。其他并发症有胸腔积液、脓胸、气腹和气胸。超过一半(57.1%)的并发症患者在就诊时为低氧血症。并发肺炎与住院时间延长和死亡风险显著相关。结论:奥索博市肺炎住院患儿并发症较多。心力衰竭是最常见的并发症。肺炎并发症和低氧血症的存在是这种环境下死亡率的重要因素。关键词:肺炎,并发症,五岁以下儿童,尼日利亚
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引用次数: 2
Mothers’ knowledge and utilization of non-routine childhood immunisation in Ibadan North Local Government Area, Oyo state, Nigeria 尼日利亚奥约州伊巴丹北部地方政府地区母亲对非常规儿童免疫接种的了解和利用情况
Pub Date : 2020-08-06 DOI: 10.4314/NJP.V47I2.8
A. Ese, V. Brown, O. Oluwatosin
Background: Vaccinepreventable- diseases are major contributors to child mortality in Africa. In Nigeria, apart from the routine childhood vaccines  that are provided free by the government, there are additional lifesaving non-routine vaccines like Rotavirus, Pneumococcal Conjugate (PCV),  Varicella, Cerebrospinal meningitis, and Measles, Mumps, Rubella (MMR) vaccines. Until 2015 when PCV was included in the routine childhood  immunisation, these five vaccines were optional and parents paid to immunize their children with them.Objective: To assess the level of knowledge and utilization of nonroutine immunisations among mothers.Methodology: A descriptive, cross -sectional study conducted in three infant welfare clinics purposively selected in Ibadan North Local Government Area, Oyo State, Nigeria. Participants were 110 mothers of children aged 6-24 months. A structured questionnaire was used for data collection and analysis done using SPSS version 20.0. Descriptive statistics were computed and Chi-square test was used for investigating association between  categorical variables at 0.05 level of significance.Results: The findings revealed that 62 (56.4%) of the 110 mothers were aware of non-routine immunisation of which 23 (20.9%) had good knowledge about it. Only 23 (20.9%) of their children were immunized with all the nonroutine vaccines. High income, higher level of education and good knowledge level about non-routine immunisation of mothers were associated with the utilization of all non-routine immunisation among their children (p<0.01).Conclusion: Knowledge of mothers about non-routine immunisation was poor and uptake of the vaccines among their children low. Health  education to improve mothers’ knowledge and utilization of non-routine immunisation by their children is recommended. Keywords: Vaccine-preventablediseases, Children, Optional, Immunisation, Awareness, Uptake, Ibadan, Nigeria 
背景:疫苗可预防的疾病是非洲儿童死亡的主要原因。在尼日利亚,除了由政府免费提供的常规儿童疫苗外,还有其他挽救生命的非常规疫苗,如轮状病毒、肺炎球菌结合疫苗、水痘、脑脊髓膜炎和麻疹、腮腺炎、风疹(MMR)疫苗。直到2015年,当PCV被纳入常规儿童免疫接种时,这五种疫苗是可选的,父母付钱给他们的孩子接种它们。目的:了解母亲对非常规免疫接种的知识和利用情况。方法:在尼日利亚奥约州伊巴丹北部地方政府区有意选择的三个婴儿福利诊所进行描述性横断面研究。参与者是110名6-24个月大孩子的母亲。采用结构化问卷进行数据收集和分析,使用SPSS 20.0版本。进行描述性统计,采用卡方检验在0.05显著水平下对分类变量进行相关性分析。结果:110名母亲中有62人(56.4%)了解非常规免疫接种,其中23人(20.9%)了解非常规免疫接种。只有23名(20.9%)儿童接种了所有非常规疫苗。母亲收入高、受教育程度高、非常规免疫知识水平高与子女使用所有非常规免疫相关(p<0.01)。结论:母亲对非常规免疫的认识较差,其子女对疫苗的接种率较低。建议开展健康教育,以提高母亲对儿童非常规免疫接种的认识和利用。关键词:疫苗可预防疾病,儿童,可选,免疫接种,意识,吸收,伊巴丹,尼日利亚
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引用次数: 0
Prevalence and factors associated with non-adherence to antiepileptic drugs among children with epilepsy in Jos, Nigeria 尼日利亚乔斯市癫痫患儿中抗癫痫药物不依从性的患病率及相关因素
Pub Date : 2020-08-06 DOI: 10.4314/NJP.V47I3.8
E. U. Ejeliogu, A. Courage
Background: Childhood epilepsy causes a tremendous burden for the child, the family, society as well as the healthcare system. Adherence toantiepileptic drugs (AEDs) is key to treatment success, one of the main causes of unsuccessful treatment for epilepsy is poor adherence to medications. Nonadherence in children with epilepsy presents a potential ongoing challenge for achieving a key therapeutic goal of seizure control.Aim: To determine the prevalence and factors associated with nonadherence to AEDs among children with epilepsy at Jos University Teaching Hospital, Jos, Nigeria.Methodology: This cross sectional study was done to assess the prevalence and factors associated with non-adherence to AEDs among children with epilepsy from November 2019 to February 2020. A structured questionnaire was used to collect relevant information on the adherence of studysubjects to AEDs based on self/ caregiver report. Part of the questionnaire was derived from Morisky Medication Adherence Scale (MMAS-8).Results: One hundred and ninety four subjects were recruited for the study. The prevalence of nonadherence to AEDs was 44.8%. Factors significantly associated with non-adherence were low socioeconomic status, multiple drug therapy and long duration of treatment. The main reasons for nonadherence were financial constraint, forgetfulness, lack of improvement and medication side effects.Conclusion: Non-adherence to medication is common among children with epilepsy and it hampers the key therapeutic goal of seizure control. Improving per capita income of families, providing universal health insurance, medication reminders and appropriate education/counseling will reduce non-adherence and improve the long term outcome of childhood epilepsy in our region. Key words: Epilepsy, Children, Ant i -epilept ic drugs, Nonadherence, Prevalence, Associated factors, Jos, Nigeria.
背景:儿童癫痫给儿童、家庭、社会以及卫生保健系统造成巨大负担。抗癫痫药物的依从性是治疗成功的关键,癫痫治疗失败的主要原因之一是药物依从性差。癫痫患儿的不依从性是实现癫痫控制这一关键治疗目标的潜在持续挑战。目的:确定尼日利亚乔斯乔斯大学教学医院癫痫患儿中抗癫痫药不依从性的患病率及相关因素。方法:本横断面研究旨在评估2019年11月至2020年2月癫痫患儿中抗癫痫药不依从性的患病率及相关因素。采用结构化问卷收集研究对象在自我/照顾者报告的基础上对aed的依从性的相关信息。部分问卷来源于Morisky药物依从性量表(MMAS-8)。结果:共招募了194名受试者。不遵医嘱的发生率为44.8%。与不依从性显著相关的因素是低社会经济地位、多种药物治疗和治疗时间长。不坚持治疗的主要原因是经济拮据、健忘、缺乏改善和药物副作用。结论:癫痫患儿用药不依从现象普遍,影响了癫痫发作控制的关键治疗目标。提高家庭人均收入、提供全民健康保险、提醒用药和适当的教育/咨询将减少不遵守规定的情况,并改善本区域儿童癫痫的长期后果。关键词:癫痫,儿童,抗癫痫药物,不依从,患病率,相关因素,乔斯,尼日利亚
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引用次数: 6
期刊
Nigerian journal of paediatrics
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