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[Feasibility of CT attenuation values in the diagnosis of anemia]. 【CT衰减值在贫血诊断中的可行性】。
Youichi Sato, Eito Kozawa, Shunji Tsukuda, Makoto Amanuma

Purpose: To verify the possible correlation between CT attenuation value and hemoglobin (Hb).

Materials and methods: CT attenuation was evaluated in 113 CT studies. Anemia was defined as an Hb level less than 14 g/dl in males and less than 12 g/dl in females. Hb was compared visually by grading (Grade 1: cardiac muscle density much higher than lumen, Grade 2: cardiac muscle density higher than lumen, Grade 3: cardiac muscle density equal to lumen), and with HU of CT attenuation on unpaired t-test (p<0.01). Correlations were calculated using the linear regression method.

Results: Hb of less than 6 g/dl was found to be Grade 1, while that over 12 g/dl was considered Grade 3 on visual grading. The attenuation numbers of subjects with anemia yielded low values, whereas those of normal subjects were higher. There were significant differences between subjects with anemia and normal subjects (p<0.01). HU versus hemoglobin showed a linear increase, with a correlation coefficient of 0.76.

Conclusions: This simple, readily available information may provide a valuable adjunct in the interpretation of CT examinations.

目的:验证CT衰减值与血红蛋白(Hb)的可能相关性。材料和方法:对113例CT研究进行了CT衰减评价。贫血被定义为男性Hb水平低于14g /dl,女性低于12g /dl。通过视觉分级(1级:心肌密度远高于管腔,2级:心肌密度高于管腔,3级:心肌密度等于管腔)和未配对t检验的CT衰减HU(结果:Hb小于6 g/dl为1级,大于12 g/dl为3级视觉分级)比较Hb。贫血受试者的衰减值较低,而正常受试者的衰减值较高。结论:这种简单、容易获得的信息可能为CT检查的解释提供有价值的辅助。
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引用次数: 0
[History of radiation therapy]. [放射治疗史]。
Yukio Tateno
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引用次数: 0
[Proposal for a system of recording radiation exposure for individual patients]. [关于建立个体病人辐射暴露记录系统的建议]。
Norinobu Honda
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引用次数: 0
[Radiation exposure doses in medical procedures]. [医疗过程中的辐射暴露剂量]。
Kazuo Awai

An investigation was conducted concerning long-term changes of patients' radiation exposure doses in medical procedures such as chest X-ray and CT scans. The result of the investigation compelled consideration of methods for reducing the exposure doses. While the exposure doses have decreased in chest X-ray compared with 30 years ago, they have remained unchanged in CT scan compared with 20 years ago. The following address possible causes of unchanged doses for CT scan: Measuring doses is difficult. Technology to reduce patients' doses has yet to be used effectively. It is important to take deterministic causes into consideration. More research and attention to the issue are needed.

对诸如胸部x光和CT扫描等医疗程序中患者辐射暴露剂量的长期变化进行了调查。调查的结果迫使人们考虑减少照射剂量的方法。虽然与30年前相比,胸部x射线的暴露剂量有所下降,但与20年前相比,CT扫描的暴露剂量没有变化。以下是CT扫描剂量不变的可能原因:测量剂量是困难的。减少患者剂量的技术尚未得到有效利用。考虑决定性的原因是很重要的。需要对这个问题进行更多的研究和关注。
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引用次数: 0
[Risk of radiation-related cancer following exposure to diagnostic radiation]. [诊断性辐射暴露后患辐射相关癌症的风险]。
Michiaki Kai

The paper on the risk of radiation-related cancer following exposure to diagnostic X-ray, appeared in the issue of Jan 31, 2004 of the Lancet, and described an attributable risk estimate of 3.2% from the current medical exposure among the cancer incidences in Japan. While the fact that Japan is known as a country with the highest level of medical exposure, the quantification of radiation-related cancer risk have made quite an impact on medical society. The risk estimate based on the linear-non-threshold (LNT) dose response that remains unresolved scientifically need further research, but the radiation risk has been a useful tool not only for decision-making by risk-benefit analysis such as justification of medical use of radiation, but also for comparison with other risks. Recent radiation biology suggests that a bystander effect and adaptive response might modify the estimated cancer risk based on the LNT model at low doses. The risk from most diagnostic X-rays may be so small that excess cancer due to radiation can not be statistically detected. However, a diagnosis giving a relatively higher dose such as computer tomography in children should be carefully justified using a risk estimate. Raising awareness of low-dose cancer risk should involve not only understanding the process of risk estimation including data and assumption but also understanding there is indirect evidence for risk of lower level radiation exposure in medical procedures.

2004年1月31日出版的《柳叶刀》杂志发表了一篇关于接受诊断性x射线照射后患辐射相关癌症风险的论文,其中描述了日本目前的医疗照射在癌症发病率中3.2%的归因风险估计。虽然日本被认为是医疗照射水平最高的国家,但与辐射有关的癌症风险的量化对医学界产生了相当大的影响。基于线性-非阈值(LNT)剂量反应的风险估计在科学上仍有待进一步研究,但辐射风险已成为一种有用的工具,不仅可以通过风险-效益分析进行决策,如证明辐射医疗使用的合理性,而且可以与其他风险进行比较。最近的辐射生物学表明,旁观者效应和适应性反应可能会改变基于低剂量LNT模型估计的癌症风险。大多数诊断性x光的风险可能很小,以至于无法从统计上检测出辐射导致的过量癌症。然而,对于给予相对较高剂量的诊断,如对儿童进行计算机断层扫描,应谨慎地使用风险评估来证明其合理性。提高对低剂量癌症风险的认识不仅应涉及了解风险估计过程(包括数据和假设),还应涉及了解在医疗程序中存在低水平辐射暴露风险的间接证据。
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引用次数: 0
[History of radiation therapy]. [放射治疗史]。
Yukio Tateno
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引用次数: 0
[Clinical usefulness of multidetector-row CT to evaluate coronary artery calcium score in type 2 diabetes]. [多排CT评价2型糖尿病患者冠状动脉钙评分的临床价值]。
Makiko Nishioka, Toru Sakuma, Hironari Sano, Kazunori Utsunomiya, Toshihiko Agata, Keisuke Shimizu, Naoko Tajima

Purpose: According to recent studies, multidetector-row CT (MDCT) with a retrospective ECG-gating reconstruction algorithm shows a high correlation with coronary artery calcium score determined using electron-beam CT. Diabetes leads to many macrovascular complications, including coronary artery disease. The aim of this study was to evaluate risk factors for cardiac macroangiopathy in type 2 diabetes using MDCT.

Materials and methods: An observational cross-sectional study was performed in 90 patients with diabetes mellitus. Coronary calcium data was acquired by MDCT (SOMATOM Volume Zoom, Siemens AG, Medical Solutions, Germany). Physical examinations, laboratory data, glycemic control, and control of other risk factors were analyzed.

Results: The coronary artery calcium score increased with age. Multivariant analysis revealed that the coronary calcium score was closely correlated with electrocardiogram evaluation and control of hypertension.

Conclusions: Coronary artery calcium score as determined by MDCT can be used as a screening radiological examination for cardiac macroangiopathy in diabetes patients with electrocardiogram abnormality and hypertension.

目的:根据最近的研究,采用回顾性心电图门控重建算法的多排CT (multidetector-row CT, MDCT)与电子束CT测定的冠状动脉钙评分有很高的相关性。糖尿病导致许多大血管并发症,包括冠状动脉疾病。本研究的目的是利用MDCT评估2型糖尿病患者心脏大血管病变的危险因素。材料与方法:对90例糖尿病患者进行观察性横断面研究。冠状动脉钙数据由MDCT (SOMATOM Volume Zoom, Siemens AG, Medical Solutions, Germany)获取。分析体格检查、实验室数据、血糖控制和其他危险因素的控制情况。结果:冠状动脉钙化评分随年龄增长而升高。多变量分析表明,冠状动脉钙评分与心电图评价及高血压控制密切相关。结论:MDCT冠状动脉钙化评分可作为糖尿病合并心电图异常和高血压患者心脏大血管病变的影像学筛查。
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引用次数: 0
[Breast cancer screening in Japan--present status and recent movement]. 【日本乳腺癌筛查的现状及近期动向】。
Tokiko Endo

As the incidence of breast cancer and deaths from breast cancer have been increasing, the Ministry of Public Welfare and Labor has been promoting breast cancer screening. Mammography screening began in fiscal year 2000 for those women 50 years of age or over, but attendance has not been increasing. This year (2004), the Ministry determined that mammography would be applicable to those 40 years of age or over and that screening with palpation alone would be abolished. To determine the effectiveness of the measures, mammography equipment, technologists, and readers were calculated. If the attendance were 50% of the 35,497 thousand women in this biennial screening, 40 persons would be examined by one apparatus per day, and, as there are 200 working days in a year, 1,109 apparatus would be needed. In the same way, if a technologist can examine 5,000 women, and a doctor can read 10,000 cases a year, both are apparently deficient in some prefectures. The standards of quality control for digital mammography have been determined by the Japan Radiological Society, and a "step phantom for mammography" has been developed. Qualitative evaluation of hard-copy clinical images has also started. All of the standards are presented in "Mammography Guidelines, Second Edition," published by Igakushoin, Tokyo, Japan, 2004.

由于乳腺癌发病率和乳腺癌死亡人数不断增加,公共福利和劳动部一直在促进乳腺癌筛查。乳房x光检查开始于2000财政年度,针对50岁或以上的妇女,但参加人数并没有增加。今年(2004年),卫生部决定,乳房x光检查将适用于40岁或40岁以上的人,而仅用触诊进行筛查将被废除。为了确定措施的有效性,计算了乳房x光检查设备、技术人员和阅读者。如果参加这项两年一次的检查的妇女人数为35,49.7万名妇女的50%,那么每天将有40人接受一台仪器的检查,由于一年有200个工作日,因此需要1109台仪器。同样,如果一名技术人员每年可以检查5000名妇女,一名医生每年可以阅读10000例病例,那么在某些县,这两者显然都是不足的。日本放射学会确定了数字乳房x线照相术的质量控制标准,并开发了“乳房x线照相术的阶梯模型”。对临床硬拷贝影像的定性评价也已开始。所有的标准都在2004年日本东京Igakushoin出版的《乳房x线照相术指南第二版》中提出。
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引用次数: 0
[A case of extrapontine myelinolysis precipitated by correction of a hyper-osmolar state]. [1例高渗透压状态矫正引起的外胆管髓鞘溶解]。
Sachiko Achiwa, Kumiko Ando, Reiichi Ishikura, Yoshihiro Takada, Yusuke Takahashi

We report a case of extrapontine myelinolysis (EPM) precipitated by correction of a hyper-osmolar state. A 7-year-old boy presented with disturbed consciousness. Serum BUN and Na level were 48 mg/dl and 196 mmol/L, respectively. T2-weighted images and FLAIR images of MRI visualized symmetrical bilateral high signal intensity areas in the external capsule and in the thalamus. In addition, the splenium of the corpus callosum showed high signal intensity. All these lesions showed high signal intensity on diffusion-weighted images. Extrapontine myelinolysis is precipitated not only by the rapid correction of a hypo-osmolar state but also by that of a hyper-osmolar state.

我们报告一例高渗透压状态的纠正所导致的粥外质髓鞘溶解(EPM)。一名七岁男孩表现为意识紊乱。血清BUN和Na水平分别为48 mg/dl和196 mmol/L。MRI t2加权图像和FLAIR图像显示双侧外囊和丘脑内对称的高信号区。胼胝体脾部呈高信号。所有病变在弥散加权图像上均显示高信号强度。蛋白外髓鞘溶解不仅是由低渗透压状态的快速纠正引起的,而且也是由高渗透压状态引起的。
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引用次数: 0
[A comparative study of CT and barium enema examination in diagnosis of peritoneal metastasis from gastric carcinoma]. 【CT与钡灌肠检查诊断胃癌腹膜转移的比较研究】。
Satoshi Nozu, Tetsuo Nakajima, Toshihiro Ichikawa, Katsuhiko Okayasu

Objective: To compare the results of CT and barium enema examination in the diagnosis of peritoneal metastasis from gastric carcinoma.

Materials: Peritoneal metastases were pathologically confirmed in nine patients with gastric carcinoma who had had abdominal CT and barium enema examinations prior to surgery.

Methods and results: Five patients were reported to have colonic wall rigidity on preoperative barium enema examination. Review of the images indicated that six cases showed rigidity. On the other hand, no CT findings suggestive of peritoneal metastasis were reported in eight patients without ascites. No patients were indicated to have intraperitoneal nodules. For the retrospective evaluation, we changed the diagnostic procedure: the CT window setting was changed in wide window width (from 250 Hounsfield units (HU) to 400HU)and low window level (50-60HU to 0 HU), and reading mode was changed to a cine paging mode with a picture archiving and communication system (PACS) instead of hard-copy review. It followed that intraperitoneal nodules suggestive of peritoneal metastasis were detected in eight patients.

Conclusion: On conventional image reading, barium enema examination is of greater assistance than CT examination for detecting peritoneal metastasis from gastric carcinoma. However, the new CT reading method with PACS is more sensitive than barium enema examination for diagnosing peritoneal metastasis.

目的:比较CT与钡灌肠检查对胃癌腹膜转移的诊断价值。资料:9例术前行腹部CT及钡剂灌肠检查的胃癌患者经病理证实有腹膜转移。方法与结果:报告5例患者术前钡剂灌肠检查发现结肠壁僵直。复查图像显示6例表现为僵直。另一方面,8例无腹水的患者未见提示腹膜转移的CT表现。没有患者显示有腹膜内结节。为了进行回顾性评价,我们改变了诊断程序:将CT窗口设置改为宽窗口宽度(从250 Hounsfield单位(HU)改为400HU)和低窗口电平(从50-60HU改为0HU),并将阅读模式改为带有图片存档和通信系统(PACS)的电影分页模式,而不是硬拷贝审查。在8例患者中发现提示腹膜转移的腹膜内结节。结论:在常规影像学上,钡剂灌肠检查对胃癌腹膜转移的诊断价值高于CT检查。然而,新的CT阅读方法与PACS诊断腹膜转移比钡灌肠检查更敏感。
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Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica
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