Pub Date : 2023-07-04DOI: 10.14412/20742711-2023-3-60-67
V. Vysokova, N. A. Tyuvina, T. N. Maksimova, S. V. Prokhorova
Objective: to study the clinical features of mental disorders during the COVID-19 epidemic in those who turned to psychiatrist for the first time, as well as in patients with already diagnosed mental illness.Material and methods. We examined 100 patients who turned to psychiatrist due to deterioration of their mental state on the background of a pandemic. Of these, 50 were new cases (1st group; 23 women and 27 men, mean age 34 years) and 50 were cases with previously diagnosed mental disorders (2nd group; 25 women and 25 men, mean age 37 years). 80% of patients of the 1st group, 54% of patients of the 2nd group had coronavirus infection. Anxiety and depressive disorders prevailed in the 1st group, endogenous diseases prevailed in the 2nd group: bipolar affective disorder, recurrent depressive disorder, schizophrenia. The study was conducted by the clinical method using a specially designed map; the severity of depression was assessed using the Montgomery-Asberg Depression Rating Scale, and the severity of anxiety was assessed using the Hamilton Anxiety Rating Scale.Results. The clinical picture of primary and recurrent depressive episodes after infection was characterized by the presence of motor and associative retardation, severe apathy, hypersomnia and lack of sleep, fatigue, increased appetite, and complaints of impaired attention and memory. Depression in SARS-CoV-2 survivors was characterized by anxiety, anhedonia, irritability, somatic complaints, and hypochondriacal inclusions. Anxiety symptoms in those who were not ill included severe anxiety, reaching agitation, disturbed sleep with frequent awakenings, irritability, somatic complaints, and hypochondriacal fixation on one’s condition. In recovering patients, anxiety was accompanied by control of somatic functions, cognitive impairments, and fear of retention or even intensification.Conclusion. The results obtained indicate the existing differences between the mental disorders that first appeared and worsened during the pandemic, as well as the differences in the structure of the depressive and anxiety syndrome depending on the presence or absence of coronavirus infection.
{"title":"Mental disorders during the pandemic of a new coronavirus infection: clinical features","authors":"V. Vysokova, N. A. Tyuvina, T. N. Maksimova, S. V. Prokhorova","doi":"10.14412/20742711-2023-3-60-67","DOIUrl":"https://doi.org/10.14412/20742711-2023-3-60-67","url":null,"abstract":"Objective: to study the clinical features of mental disorders during the COVID-19 epidemic in those who turned to psychiatrist for the first time, as well as in patients with already diagnosed mental illness.Material and methods. We examined 100 patients who turned to psychiatrist due to deterioration of their mental state on the background of a pandemic. Of these, 50 were new cases (1st group; 23 women and 27 men, mean age 34 years) and 50 were cases with previously diagnosed mental disorders (2nd group; 25 women and 25 men, mean age 37 years). 80% of patients of the 1st group, 54% of patients of the 2nd group had coronavirus infection. Anxiety and depressive disorders prevailed in the 1st group, endogenous diseases prevailed in the 2nd group: bipolar affective disorder, recurrent depressive disorder, schizophrenia. The study was conducted by the clinical method using a specially designed map; the severity of depression was assessed using the Montgomery-Asberg Depression Rating Scale, and the severity of anxiety was assessed using the Hamilton Anxiety Rating Scale.Results. The clinical picture of primary and recurrent depressive episodes after infection was characterized by the presence of motor and associative retardation, severe apathy, hypersomnia and lack of sleep, fatigue, increased appetite, and complaints of impaired attention and memory. Depression in SARS-CoV-2 survivors was characterized by anxiety, anhedonia, irritability, somatic complaints, and hypochondriacal inclusions. Anxiety symptoms in those who were not ill included severe anxiety, reaching agitation, disturbed sleep with frequent awakenings, irritability, somatic complaints, and hypochondriacal fixation on one’s condition. In recovering patients, anxiety was accompanied by control of somatic functions, cognitive impairments, and fear of retention or even intensification.Conclusion. The results obtained indicate the existing differences between the mental disorders that first appeared and worsened during the pandemic, as well as the differences in the structure of the depressive and anxiety syndrome depending on the presence or absence of coronavirus infection.","PeriodicalId":19252,"journal":{"name":"Neurology, neuropsychiatry, Psychosomatics","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73383625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-04DOI: 10.14412/2074-2711-2023-3-121-127
Z. Zalyalova, E. V. Ekusheva
Parkinson’s disease (PD) is a progressive neurodegenerative disease with various clinical manifestations, its origin not always can be explained only by dopamine deficiency. Long-term treatment with levodopa (especially its intraduodenal administration), as well as clinical manifestations of polyneuropathy, cognitive deficits, postural disorders with freezing of gate, REM sleep behavioral disorders, are more often associated with vitamin B12 deficiency. Several reasons for this association and mechanisms of their development are discussed. Early detection of cobalamin deficiency in PD, especially in patients from high-risk groups, makes it possible to stop this pathological condition timely and prevent irreversible changes. Modern data on the use of high-dose (1000 μ g) oral vitamin B12 are presented, it has comparable clinical efficacy and significant advantages, compared with the parenteral form, in terms of the ease of use and the ability to avoid undesirable postinjection reactions.
{"title":"Vitamin B12 deficiency and Parkinson’s disease","authors":"Z. Zalyalova, E. V. Ekusheva","doi":"10.14412/2074-2711-2023-3-121-127","DOIUrl":"https://doi.org/10.14412/2074-2711-2023-3-121-127","url":null,"abstract":"Parkinson’s disease (PD) is a progressive neurodegenerative disease with various clinical manifestations, its origin not always can be explained only by dopamine deficiency. Long-term treatment with levodopa (especially its intraduodenal administration), as well as clinical manifestations of polyneuropathy, cognitive deficits, postural disorders with freezing of gate, REM sleep behavioral disorders, are more often associated with vitamin B12 deficiency. Several reasons for this association and mechanisms of their development are discussed. Early detection of cobalamin deficiency in PD, especially in patients from high-risk groups, makes it possible to stop this pathological condition timely and prevent irreversible changes. Modern data on the use of high-dose (1000 μ g) oral vitamin B12 are presented, it has comparable clinical efficacy and significant advantages, compared with the parenteral form, in terms of the ease of use and the ability to avoid undesirable postinjection reactions.","PeriodicalId":19252,"journal":{"name":"Neurology, neuropsychiatry, Psychosomatics","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89711798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-04DOI: 10.14412/2074-2711-2023-3-54-59
A. A. Borzdyko, V. I. Ershov, N. V. Gumalatova, T. Lozinskaya, E. Lutsai
Objective: to determine prognostic characteristics of the restoration of swallowing function in patients with ischemic stroke (IS) of various pathogenetic subtypes.Material and methods. The study included 110 patients (64 men and 46 women aged 44–89 years) with dysphagia in the acute period of IS. The SSS-TOAST criteria were used to diagnose the pathogenetic subtype, and the MASA scale was used to determine the presence and severity of dysphagia. To predict the probability of switching to self-feeding depending on the severity of dysphagia, a non-linear regression method was used using the least squares method.Results. Patients with cardioembolic stroke subtype were initially characterized by a greater degree of dysphagia in comparison with patients with atherothrombotic stroke subtype in groups comparable in severity (p<0.05). In the cardioembolic subtype of IS, the probability of switching patients to self-feeding on the 21st day in groups with dysphagia severity from 105 to 135 points on the MASA scale was lower than in the atherothrombotic subtype of IS (p<0.05).Conclusion. Patients with cardioembolic strokes are characterized by more severe initial dysphagia and a worse prognosis for recovery of swallowing function compared to patients with atherothrombotic strokes.
{"title":"Prediction of restoration of swallowing function in patients with ischemic stroke and neurogenic dysphagia","authors":"A. A. Borzdyko, V. I. Ershov, N. V. Gumalatova, T. Lozinskaya, E. Lutsai","doi":"10.14412/2074-2711-2023-3-54-59","DOIUrl":"https://doi.org/10.14412/2074-2711-2023-3-54-59","url":null,"abstract":"Objective: to determine prognostic characteristics of the restoration of swallowing function in patients with ischemic stroke (IS) of various pathogenetic subtypes.Material and methods. The study included 110 patients (64 men and 46 women aged 44–89 years) with dysphagia in the acute period of IS. The SSS-TOAST criteria were used to diagnose the pathogenetic subtype, and the MASA scale was used to determine the presence and severity of dysphagia. To predict the probability of switching to self-feeding depending on the severity of dysphagia, a non-linear regression method was used using the least squares method.Results. Patients with cardioembolic stroke subtype were initially characterized by a greater degree of dysphagia in comparison with patients with atherothrombotic stroke subtype in groups comparable in severity (p<0.05). In the cardioembolic subtype of IS, the probability of switching patients to self-feeding on the 21st day in groups with dysphagia severity from 105 to 135 points on the MASA scale was lower than in the atherothrombotic subtype of IS (p<0.05).Conclusion. Patients with cardioembolic strokes are characterized by more severe initial dysphagia and a worse prognosis for recovery of swallowing function compared to patients with atherothrombotic strokes.","PeriodicalId":19252,"journal":{"name":"Neurology, neuropsychiatry, Psychosomatics","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82652361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-04DOI: 10.14412/2074-2711-2023-3-114-120
A. B. Lokshina, D. Grishina
Stroke is second to third most common cause of death in the population and the leading cause of disability. More than 12 million strokes are registered annually in the world. Cognitive impairments (CI) significantly contribute to the disability of patients after a stroke, which limit daily activities no less than movement disorders. The article presents data on the prevalence of post-stroke CI (PSCI), examines the issues of epidemiology, risk factors, the main clinical and pathogenetic data of disorders, the peculiarities of their diagnosis and treatment. The issues of the dipyridamole use for the prevention of stroke and in patients with PSCI are discussed.
{"title":"Issues of management of patients with post-stroke cognitive impairment","authors":"A. B. Lokshina, D. Grishina","doi":"10.14412/2074-2711-2023-3-114-120","DOIUrl":"https://doi.org/10.14412/2074-2711-2023-3-114-120","url":null,"abstract":"Stroke is second to third most common cause of death in the population and the leading cause of disability. More than 12 million strokes are registered annually in the world. Cognitive impairments (CI) significantly contribute to the disability of patients after a stroke, which limit daily activities no less than movement disorders. The article presents data on the prevalence of post-stroke CI (PSCI), examines the issues of epidemiology, risk factors, the main clinical and pathogenetic data of disorders, the peculiarities of their diagnosis and treatment. The issues of the dipyridamole use for the prevention of stroke and in patients with PSCI are discussed.","PeriodicalId":19252,"journal":{"name":"Neurology, neuropsychiatry, Psychosomatics","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78587154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-04DOI: 10.14412/2074-2711-2023-3-76-81
E. O. Garcés, Caroline Rech, Mauro Azambuja, Daiandy da Silva, José Bragatti, Jordana, Guimarães, F. Thomé
Cefepime is a fourth-generation cephalosporin antibiotic widely used in clinical practice for various organ systems pathology treatment. The article describes the clinical observation of a patient who, 3 days after cefepime administration, had a decrease in the level of consciousness, regarded as encephalopathy. Cefepime-induced neurotoxicity is characterized by toxic encephalopathy, which manifests 2–6 days after the start of the treatment with this drug and disappears 1–3 days after its withdrawal. Electroencephalography (EEG) abnormalities include generalized periodic discharges (GPR) of triphasic morphology or a pattern corresponding to the criteria for non-convulsive status epilepticus (BSES). In our observation, the EEG recorded stimulus-induced GPRs of triphasic morphology with a frequency of 1.5 Hz; a test with intravenous administration of an antiepileptic drug (levetiracetam) was negative. A day after the withdrawal of cefepime, the patient’s level of consciousness returned to the initial level, and on the EEG periodic discharges completely regressed. Thus, cefepime may cause encephalopathy in patients with rhythmic or intermittent EEG activity, especially in the presence of a stimulus-induced component. In some cases, the use of cefepime may develop epileptic seizures and BSES.
{"title":"Cefepime-induced encephalopathy","authors":"E. O. Garcés, Caroline Rech, Mauro Azambuja, Daiandy da Silva, José Bragatti, Jordana, Guimarães, F. Thomé","doi":"10.14412/2074-2711-2023-3-76-81","DOIUrl":"https://doi.org/10.14412/2074-2711-2023-3-76-81","url":null,"abstract":"Cefepime is a fourth-generation cephalosporin antibiotic widely used in clinical practice for various organ systems pathology treatment. The article describes the clinical observation of a patient who, 3 days after cefepime administration, had a decrease in the level of consciousness, regarded as encephalopathy. Cefepime-induced neurotoxicity is characterized by toxic encephalopathy, which manifests 2–6 days after the start of the treatment with this drug and disappears 1–3 days after its withdrawal. Electroencephalography (EEG) abnormalities include generalized periodic discharges (GPR) of triphasic morphology or a pattern corresponding to the criteria for non-convulsive status epilepticus (BSES). In our observation, the EEG recorded stimulus-induced GPRs of triphasic morphology with a frequency of 1.5 Hz; a test with intravenous administration of an antiepileptic drug (levetiracetam) was negative. A day after the withdrawal of cefepime, the patient’s level of consciousness returned to the initial level, and on the EEG periodic discharges completely regressed. Thus, cefepime may cause encephalopathy in patients with rhythmic or intermittent EEG activity, especially in the presence of a stimulus-induced component. In some cases, the use of cefepime may develop epileptic seizures and BSES.","PeriodicalId":19252,"journal":{"name":"Neurology, neuropsychiatry, Psychosomatics","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79331536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-04DOI: 10.14412/2074-2711-2023-3-139-143
A. Editorial
On March 31, 2023, the first meeting of the Council of Experts was held in Moscow to discuss new options for the treatment of chronic cerebral ischemia (CCI), one of the most common causes of vascular cognitive impairment in middle-aged and elderly patients. The issues of screening, diagnosis and treatment of patients with CCI, including through the interaction of neurologists with related specialists, are discussed.
{"title":"Resolution of the Council of Experts on the topic “New treatment options for patients with chronic cerebral ischemia”, March 31, 2023","authors":"A. Editorial","doi":"10.14412/2074-2711-2023-3-139-143","DOIUrl":"https://doi.org/10.14412/2074-2711-2023-3-139-143","url":null,"abstract":"On March 31, 2023, the first meeting of the Council of Experts was held in Moscow to discuss new options for the treatment of chronic cerebral ischemia (CCI), one of the most common causes of vascular cognitive impairment in middle-aged and elderly patients. The issues of screening, diagnosis and treatment of patients with CCI, including through the interaction of neurologists with related specialists, are discussed.","PeriodicalId":19252,"journal":{"name":"Neurology, neuropsychiatry, Psychosomatics","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80295222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-04DOI: 10.14412/2074-2711-2023-3-85-94
V. Golovacheva, G. Tabeeva, A. A. Golovacheva
Non-specific low back pain (LBP) occurs in most people at least once in a lifetime. In city polyclinics, every fourth patient complains of LBP. During the COVID-19 pandemic, the prevalence of acute non-specific LBP and chronic LBP have increased due to physical inactivity, chronic stress, and anxiety. Musculoskeletal LBP is the second most common cause of disability. In this regard, it is important to consider modern principles for the diagnosis and treatment of non-specific LBP. Diagnostic algorithms, “red flags” (dangerous symptoms), “yellow flags” (chronification factors) in LBP are discussed. Own clinical cases of patients with LBP with “red flags” are presented. Effective drug and non-drug methods of treatment of LBP are considered: patient education, kinesiotherapy, cognitive-behavioral therapy, manual therapy, the use of non-steroidal anti-inflammatory drugs, muscle relaxants. The role of aceclofenac and tolperisone in the treatment of LBP is discussed, clinical studies data on the efficacy and safety of these drugs in pain syndromes are presented. We present our own clinical observation of the successful management of a patient with chronic non-specific LBP.
{"title":"Non-specific low back pain: principles and algorithms for successful management of patients in real clinical practice","authors":"V. Golovacheva, G. Tabeeva, A. A. Golovacheva","doi":"10.14412/2074-2711-2023-3-85-94","DOIUrl":"https://doi.org/10.14412/2074-2711-2023-3-85-94","url":null,"abstract":"Non-specific low back pain (LBP) occurs in most people at least once in a lifetime. In city polyclinics, every fourth patient complains of LBP. During the COVID-19 pandemic, the prevalence of acute non-specific LBP and chronic LBP have increased due to physical inactivity, chronic stress, and anxiety. Musculoskeletal LBP is the second most common cause of disability. In this regard, it is important to consider modern principles for the diagnosis and treatment of non-specific LBP. Diagnostic algorithms, “red flags” (dangerous symptoms), “yellow flags” (chronification factors) in LBP are discussed. Own clinical cases of patients with LBP with “red flags” are presented. Effective drug and non-drug methods of treatment of LBP are considered: patient education, kinesiotherapy, cognitive-behavioral therapy, manual therapy, the use of non-steroidal anti-inflammatory drugs, muscle relaxants. The role of aceclofenac and tolperisone in the treatment of LBP is discussed, clinical studies data on the efficacy and safety of these drugs in pain syndromes are presented. We present our own clinical observation of the successful management of a patient with chronic non-specific LBP.","PeriodicalId":19252,"journal":{"name":"Neurology, neuropsychiatry, Psychosomatics","volume":"76 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88214523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-03DOI: 10.14412/2074-2711-2023-3-35-40
I. Bakulin, A. Zabirova, A. Poydasheva, D. Lagoda, N. Suponeva, M. Piradov
Transcranial magnetic stimulation (TMS) is increasingly used in research and clinical practice, therefore, the issues of its safety and tolerability are especially important. Currently, serious adverse reactions (ARs) are extremely rare. The more common mild ARs that can develop during and after stimulation remain less well understood but may affect procedure tolerance and treatment adherence.Objective: to study the tolerability and safety of TMS in patients and healthy volunteers.Material and methods. In a retrospective cohort study using standardized questionnaires, ARs were assessed during and within 24 hours after TMS in patients (n=103) and healthy volunteers (n=74).Results. In total, the data of 1246 sessions were analyzed. ARs were observed during 56.8% of the analyzed sessions and within 24 hours after in 21.5% of the sessions. In most cases, they were mild and did not affect the intent to continue stimulation. TMS withdrawal due to ARs was reported in six cases (3.3% of participants), three of which experienced severe headache (HA) after stimulation. During stimulation, sleepiness (32.4%) and pain in the stimulation area (20.3%) were most often recorded. The most frequent AR within 24 hours after TMS was HA (13.3% of sessions), its characteristics are described and possible diagnostic criteria are proposed.Conclusion. ARs can occur during and after a TMS session and are mild in most cases. TMS-induced HA, which is the most common AR within 24 hours after TMS, can be considered a distinct type of secondary HA, the pathogenesis of which requires further study.
{"title":"Safety and tolerability of repetitive transcranial magnetic stimulation: an analysis of over 1200 sessions","authors":"I. Bakulin, A. Zabirova, A. Poydasheva, D. Lagoda, N. Suponeva, M. Piradov","doi":"10.14412/2074-2711-2023-3-35-40","DOIUrl":"https://doi.org/10.14412/2074-2711-2023-3-35-40","url":null,"abstract":"Transcranial magnetic stimulation (TMS) is increasingly used in research and clinical practice, therefore, the issues of its safety and tolerability are especially important. Currently, serious adverse reactions (ARs) are extremely rare. The more common mild ARs that can develop during and after stimulation remain less well understood but may affect procedure tolerance and treatment adherence.Objective: to study the tolerability and safety of TMS in patients and healthy volunteers.Material and methods. In a retrospective cohort study using standardized questionnaires, ARs were assessed during and within 24 hours after TMS in patients (n=103) and healthy volunteers (n=74).Results. In total, the data of 1246 sessions were analyzed. ARs were observed during 56.8% of the analyzed sessions and within 24 hours after in 21.5% of the sessions. In most cases, they were mild and did not affect the intent to continue stimulation. TMS withdrawal due to ARs was reported in six cases (3.3% of participants), three of which experienced severe headache (HA) after stimulation. During stimulation, sleepiness (32.4%) and pain in the stimulation area (20.3%) were most often recorded. The most frequent AR within 24 hours after TMS was HA (13.3% of sessions), its characteristics are described and possible diagnostic criteria are proposed.Conclusion. ARs can occur during and after a TMS session and are mild in most cases. TMS-induced HA, which is the most common AR within 24 hours after TMS, can be considered a distinct type of secondary HA, the pathogenesis of which requires further study.","PeriodicalId":19252,"journal":{"name":"Neurology, neuropsychiatry, Psychosomatics","volume":"77 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82358381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-03DOI: 10.14412/2074-2711-2023-3-11-15
M. G. Bashlachev, G. Evzikov
Periarticular cysts of the facet joints are relatively rare and occur predominantly (95%) in the lumbar spine, the effectiveness of their surgical treatment requires further study.Objective: to give a detailed description of a case series of patients with periarticular cysts of the cervical spine.Material and methods. During 10 years (from 2012 to 2022) 8 patients with periarticular cysts of the cervical spine were treated in the neurosurgical department of the Clinic of Nervous System Diseases of Sechenov University. All patients underwent decompressive surgery. The severity of the pain syndrome was assessed by the visual analogue scale (VAS) of pain, the degree of disability – by the disability index (DI) due to neck pain.Results. After surgical treatment, the pain syndrome decreased from 7.25±1.28 to 2.13±1.12 points according to VAS (p<0.01), disability according to DI decreased from 51.5±8.08 to 21.25± 4.5 points (p<0.01), all patients achieved a significant (50% or more) reduction in pain. None of the patients had complications during surgical treatment.Conclusion. Microsurgical removal of periarticular cysts at the cervical level can significantly reduce pain and disability.
{"title":"Periarticular cysts of the cervical spine","authors":"M. G. Bashlachev, G. Evzikov","doi":"10.14412/2074-2711-2023-3-11-15","DOIUrl":"https://doi.org/10.14412/2074-2711-2023-3-11-15","url":null,"abstract":"Periarticular cysts of the facet joints are relatively rare and occur predominantly (95%) in the lumbar spine, the effectiveness of their surgical treatment requires further study.Objective: to give a detailed description of a case series of patients with periarticular cysts of the cervical spine.Material and methods. During 10 years (from 2012 to 2022) 8 patients with periarticular cysts of the cervical spine were treated in the neurosurgical department of the Clinic of Nervous System Diseases of Sechenov University. All patients underwent decompressive surgery. The severity of the pain syndrome was assessed by the visual analogue scale (VAS) of pain, the degree of disability – by the disability index (DI) due to neck pain.Results. After surgical treatment, the pain syndrome decreased from 7.25±1.28 to 2.13±1.12 points according to VAS (p<0.01), disability according to DI decreased from 51.5±8.08 to 21.25± 4.5 points (p<0.01), all patients achieved a significant (50% or more) reduction in pain. None of the patients had complications during surgical treatment.Conclusion. Microsurgical removal of periarticular cysts at the cervical level can significantly reduce pain and disability.","PeriodicalId":19252,"journal":{"name":"Neurology, neuropsychiatry, Psychosomatics","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80052523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-03DOI: 10.14412/2074-2711-2023-3-27-34
Y. Panikratova, E. Abdullina, I. Lebedeva, K. Y. Dmitrenko, P. G. Yuzbashian, E. Ilyina, G. P. Kostyuk, A. Andrushchenko, E. Voronova, I. Y. Dorozhenok, D. Romanov
Brain lesion studies demonstrated that the right ventral frontal/anterior insular cortex (r-VF/AI) and its functional connectivity (FC) can play an important role in belief evaluation and delusions of various content.Objective: to test the hypothesis about the associations between the functional characteristics of this region and delusions in patients with mental disorders.Material and methods. The sample included 16 patients with delusional disorder and paranoid schizophrenia. We analyzed the whole-brain FC of the r-VF/AI as well as the local coherence and amplitude of low-frequency fluctuations of BOLD signal in this region.Results. The “Conviction” item of the Brown Assessment of Beliefs Scale was positively correlated with the FC between the region of interest and a cluster in the right occipital cortex (located predominantly in the occipital fusiform gyrus and the occipital pole and slightly extending to the lingual gyrus and inferior lateral occipital cortex). Local coherence and amplitude of low-frequency fluctuations in the region of interest were not associated with clinical characteristics related to delusions.Conclusion. The correlations of delusional conviction with FC between the regions involved in belief evaluation and visual perception may reflect aberrant top-down/bottom-up or cyclic processes described within the Bayesian models of delusions.
{"title":"Functional characteristics of the right ventral frontal/anterior insular cortex in the pathogenesis of delusions: a pilot study","authors":"Y. Panikratova, E. Abdullina, I. Lebedeva, K. Y. Dmitrenko, P. G. Yuzbashian, E. Ilyina, G. P. Kostyuk, A. Andrushchenko, E. Voronova, I. Y. Dorozhenok, D. Romanov","doi":"10.14412/2074-2711-2023-3-27-34","DOIUrl":"https://doi.org/10.14412/2074-2711-2023-3-27-34","url":null,"abstract":"Brain lesion studies demonstrated that the right ventral frontal/anterior insular cortex (r-VF/AI) and its functional connectivity (FC) can play an important role in belief evaluation and delusions of various content.Objective: to test the hypothesis about the associations between the functional characteristics of this region and delusions in patients with mental disorders.Material and methods. The sample included 16 patients with delusional disorder and paranoid schizophrenia. We analyzed the whole-brain FC of the r-VF/AI as well as the local coherence and amplitude of low-frequency fluctuations of BOLD signal in this region.Results. The “Conviction” item of the Brown Assessment of Beliefs Scale was positively correlated with the FC between the region of interest and a cluster in the right occipital cortex (located predominantly in the occipital fusiform gyrus and the occipital pole and slightly extending to the lingual gyrus and inferior lateral occipital cortex). Local coherence and amplitude of low-frequency fluctuations in the region of interest were not associated with clinical characteristics related to delusions.Conclusion. The correlations of delusional conviction with FC between the regions involved in belief evaluation and visual perception may reflect aberrant top-down/bottom-up or cyclic processes described within the Bayesian models of delusions.","PeriodicalId":19252,"journal":{"name":"Neurology, neuropsychiatry, Psychosomatics","volume":"30 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90997231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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