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EpiPredict: Agent-Based Modeling of Infectious Diseases EpiPredict:基于代理的传染病建模
Pub Date : 2023-11-15 DOI: 10.1007/s13218-023-00819-4
Janik Suer, Johannes Ponge, Bernd Hellingrath
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引用次数: 0
Data Augmentation for Mask-Based Leaf Segmentation of UAV-Images as a Basis to Extract Leaf-Based Phenotyping Parameters 基于掩模的无人机图像叶片分割数据增强提取叶片表型参数
Pub Date : 2023-11-14 DOI: 10.1007/s13218-023-00815-8
Abel Barreto, Lasse Reifenrath, Richard Vogg, Fabian Sinz, Anne-Katrin Mahlein
Abstract In crop protection, disease quantification parameters such as disease incidence (DI) and disease severity (DS) are the principal indicators for decision making, aimed at ensuring the safety and productivity of crop yield. The quantification is standardized with leaf organs, defined as individual scoring units. This study focuses on identifying and segmenting individual leaves in agricultural fields using unmanned aerial vehicle (UAV), multispectral imagery of sugar beet fields, and deep instance segmentation networks (Mask R-CNN). Five strategies for achieving network robustness with limited labeled images are tested and compared, employing simple and copy-paste image augmentation techniques. The study also evaluates the impact of environmental conditions on network performance. Metrics of performance show that multispectral UAV images recorded under sunny conditions lead to a performance drop. Focusing on the practical application, we employ Mask R-CNN models in an image-processing pipeline to calculate leaf-based parameters including DS and DI. The pipeline was applied in time-series in an experimental trial with five varieties and two fungicide strategies to illustrate epidemiological development. Disease severity calculated with the model with highest Average Precision (AP) shows the strongest correlation with the same parameter assessed by experts. The time-series development of disease severity and disease incidence demonstrates the advantages of multispectral UAV-imagery in contrasting varieties for resistance, as well as the limits for disease control measurements. This study identifies key components for automatic leaf segmentation of diseased plants using UAV imagery, such as illumination and disease condition. It also provides a tool for delivering leaf-based parameters relevant to optimize crop production through automated disease quantification by imaging tools.
在作物保护中,病害发生率(DI)和病害严重程度(DS)等病害量化参数是决策的主要指标,目的是保证作物产量的安全性和生产力。用叶器官进行量化标准化,定义为单个评分单位。本研究主要利用无人机(UAV)、甜菜田多光谱图像和深度实例分割网络(Mask R-CNN)对农田单叶进行识别和分割。测试和比较了使用简单和复制粘贴图像增强技术实现有限标记图像网络鲁棒性的五种策略。研究还评估了环境条件对网络性能的影响。性能指标显示,在阳光条件下记录的多光谱无人机图像导致性能下降。着眼于实际应用,我们在一个图像处理流水线中使用Mask R-CNN模型来计算基于叶子的参数,包括DS和DI。该管道在时间序列上应用于5个品种和2种杀真菌策略的试验试验,以说明流行病学发展。用平均精度(AP)最高的模型计算的疾病严重程度与专家评估的相同参数的相关性最强。疾病严重程度和发病率的时间序列发展表明了多光谱无人机图像在对比品种抗性方面的优势,以及疾病控制测量的局限性。本研究确定了利用无人机图像实现病害植物叶片自动分割的关键要素,如光照和病害状况。它还提供了一种工具,通过成像工具的自动化疾病量化,提供与优化作物生产相关的基于叶片的参数。
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引用次数: 0
Analyzing Semantically Enriched Trajectories 分析语义丰富的轨迹
Pub Date : 2023-11-14 DOI: 10.1007/s13218-023-00818-5
Jana Seep
Abstract In order to understand what influences the movement of an object or person it is important to consider a variety of factors. These could be the visibility of certain landmarks, the current temperature or the presence of a crowded area to be avoided. These insights then can be used to understand movement in the public sector and improve our build environment, e.g. to reduce street traffic accidents or orientation in complex buildings. The following extended abstract is a summary of a doctoral thesis submitted to the University of Münster. The thesis was successfully defended in February 2023 [16]. The dissertation focuses on the analysis of so-called semantically enriched trajectories , which are used to describe observed movement. It proposes a new model based on an extended finite state machine, which allows for the representation and consideration of the information about the context of the trajectory. With the new model, we consider two main steps in trajectory analysis: First, we aim to infer a semantically enriched representative trajectory for a given cluster of trajectories. Second, we introduce a variation of the well-known k-means algorithm to calculate clusters based on the given context of trajectories. To show semantic feasibility of our approach, we conclude this work by evaluating the possibility to provide decision support for domain experts in two different public sector related contexts.
为了了解影响物体或人的运动的因素,考虑各种因素是很重要的。这些可能是某些地标的可见度,当前的温度或需要避开的拥挤区域的存在。这些见解可以用来了解公共部门的运动和改善我们的建筑环境,例如减少街道交通事故或复杂建筑的方向。以下是一篇提交给明尼苏达大学的博士论文摘要。论文于2023年2月成功答辩。本文的重点是分析所谓的语义丰富的轨迹,这是用来描述观察到的运动。提出了一种基于扩展有限状态机的新模型,该模型允许对轨迹上下文信息进行表示和考虑。在新模型中,我们考虑了轨迹分析的两个主要步骤:首先,我们的目标是为给定的轨迹簇推断一个语义丰富的代表性轨迹。其次,我们引入了著名的k-means算法的一种变体,根据给定的轨迹上下文计算聚类。为了展示我们的方法在语义上的可行性,我们通过评估在两种不同的公共部门相关背景下为领域专家提供决策支持的可能性来结束这项工作。
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引用次数: 0
How to design a value-based Chatbot for the manufacturing industry: An empirical study of an internal assistance for employees 如何为制造业设计一个基于价值的聊天机器人:对员工内部协助的实证研究
Pub Date : 2023-11-13 DOI: 10.1007/s13218-023-00817-6
Patrick Berger, Joerg von Garrel
Abstract With regard to AI as a key technology, this scientific paper deals with the identification of user drivers on the purchase decision of a cooperative AI (as explainable AI—XAI), as well as the analysis of the willingness to pay in the context of value-based pricing. Besides the economic dimension with regard to usefulness and usability of the system, the focus is mainly on the (innovative) explainable character. The analysis is carried out by a choice-based conjoint analysis (CBC) using the example of an intelligent assistance system for employees that supports internal business processes and workflows in business organizations. For this purpose, fictitious purchase offers were created under which decision-makers in manufacturing business organizations in Germany made simulated purchase decisions. The analysis shows that the target group attach great utility value to transparency in the sense of explanatory content, in addition to a high degree of interactivity and a high level of reliability.
本文将人工智能作为一项关键技术,研究了协作式人工智能(可解释的AI - xai)购买决策的用户驱动因素识别,以及基于价值定价背景下的支付意愿分析。除了关于系统的有用性和可用性的经济维度外,重点主要放在(创新的)可解释性上。该分析由基于选择的联合分析(CBC)执行,该分析使用了支持业务组织内部业务流程和工作流的员工智能辅助系统的示例。为此,我们创建了虚拟的采购报价,德国制造业企业的决策者在虚拟报价下做出了模拟的采购决策。分析表明,除了高度的互动性和高水平的可靠性外,目标群体对解释性内容意义上的透明度具有很高的实用价值。
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引用次数: 0
Dissertation Abstract: Taming Exact Inference in Temporal Probabilistic Relational Models 论文摘要:时间概率关系模型中的精确推理
Pub Date : 2023-11-10 DOI: 10.1007/s13218-023-00813-w
Marcel Gehrke
Abstract Processes in our world are of a temporal probabilistic relational nature. An epidemic is an example of such a process. This dissertation abstract uses the scenario of an epidemic to illustrate the lifted dynamic junction tree algorithm (LDJT), which is a temporal probabilistic relational inference algorithm. More specifically, we argue that existing propositional temporal probabilistic inference algorithms are not suited to model an epidemic, i.e., without accounting for the relational part, and present how LDJT uses the relational aspect. Additionally, we illustrate how LDJT preserves groups of indistinguishable objects over time and have a look at LDJT from a theoretical side.
我们世界中的过程具有时间概率关系性质。流行病就是这种过程的一个例子。摘要以传染病为例,介绍了一种时间概率关联推理算法——提升动态连接树算法(LDJT)。更具体地说,我们认为现有的命题时间概率推理算法不适合建模流行病,即不考虑关系部分,并介绍了LDJT如何使用关系方面。此外,我们说明了LDJT如何随着时间的推移保留不可区分的对象组,并从理论方面看LDJT。
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引用次数: 0
Grassland Yield Estimation Using Transfer Learning from Remote Sensing Data 基于遥感数据迁移学习的草地产量估算
Pub Date : 2023-11-07 DOI: 10.1007/s13218-023-00814-9
Elias Eder, Peter Riegler-Nurscher, Johann Prankl, Heinrich Prankl
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引用次数: 0
Towards noise robust acoustic insect detection: from the lab to the greenhouse 面向噪声鲁棒昆虫声学检测:从实验室到温室
Pub Date : 2023-10-30 DOI: 10.1007/s13218-023-00812-x
Jelto Branding, Dieter von Hörsten, Jens Karl Wegener, Elias Böckmann, Eberhard Hartung
Abstract Successful and efficient pest management is key to sustainable horticultural food production. While greenhouses already allow digital monitoring and control of their climate parameters, a lack of digital pest sensors hinders the advent of digital pest management systems. To close the control loop, digital systems need to be enabled to directly assess the state of different insect populations in a greenhouse. The presented article investigates the feasibility of acoustic sensors for insect detection in greenhouses. The study is based on an extensive dataset of acoustic insect recordings made with an array of high-quality microphones under noise-shielded conditions. By mixing these noise-free laboratory recordings with environmental sounds recorded with the same equipment in a greenhouse, different signal-to-noise ratios (SNR) are simulated. To explore the possibilities of this unique and novel dataset, two deep-learning models are trained on this simulation data. A simple spectrogram-based model represents the baseline for a comparison with a model capable of processing multi-channel raw audio data. Making use of the unique possibility of the dataset, the models are pre-trained on clean data and fine-tuned on noisy data. Under lab conditions, results show that both models can make use of not just insect flight sounds but also the much quieter sounds of insect movements. First attempts under simulated real-world conditions showed the challenging nature of this task and the potential of spatial filtering. The analysis enabled by the proposed methods for training and evaluation provided valuable insights that should be considered for future work.
成功和有效的害虫管理是可持续园艺粮食生产的关键。虽然温室已经允许对其气候参数进行数字监测和控制,但缺乏数字害虫传感器阻碍了数字害虫管理系统的出现。为了关闭控制回路,需要使数字系统能够直接评估温室中不同昆虫种群的状态。本文研究了声学传感器在温室昆虫检测中的可行性。这项研究是基于大量的昆虫声学记录数据集,这些记录是在噪声屏蔽条件下用一系列高质量麦克风录制的。通过将这些无噪声的实验室录音与温室中使用相同设备录制的环境声音混合,模拟了不同的信噪比(SNR)。为了探索这个独特而新颖的数据集的可能性,在这个模拟数据上训练了两个深度学习模型。一个简单的基于谱图的模型代表了与能够处理多通道原始音频数据的模型进行比较的基线。利用数据集的独特可能性,模型在干净数据上进行预训练,并在噪声数据上进行微调。在实验室条件下,结果表明,这两种模型不仅可以利用昆虫飞行的声音,还可以利用昆虫运动时更安静的声音。在模拟现实世界条件下的首次尝试显示了该任务的挑战性和空间滤波的潜力。拟议的培训和评价方法所能进行的分析提供了宝贵的见解,应在今后的工作中加以考虑。
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引用次数: 0
Opportunities and Challenges for AI-Based Analysis of RWD in Pharmaceutical R&D: A Practical Perspective 基于人工智能的制药研发RWD分析的机遇与挑战:一个实践视角
Pub Date : 2023-10-09 DOI: 10.1007/s13218-023-00809-6
Merle Behr, Rolf Burghaus, Christian Diedrich, Jörg Lippert
Abstract Real world data (RWD) has become an important tool in pharmaceutical research and development. Generated every time patients interact with the healthcare system when diagnoses are developed and medical interventions are selected, RWD are massive and in many regards typical big data. The use of artificial intelligence (AI) to analyze RWD seems an obvious choice. It promises new insights into medical need, drivers of diseases, and new opportunities for pharmacological interventions. When put into practice RWD analyses are challenging. The distributed generation of data, under sub-optimally standardized conditions in a patient-oriented but not information maximizing healthcare transaction, leads to a high level of sparseness and uncontrolled biases. We discuss why this needs to be addressed independent of the type of analysis approach. While classical statistical analysis and modeling approaches provide a rigorous framework for the handling of bias and sparseness, AI methods are not necessarily suited when applied naively. Special precautions need to be taken from choice of method until interpretation of results to prevent potentially harmful fallacies. The conscious use of prior medical subject matter expertise may also be required. Based on typical application examples we illustrate challenges and methodological considerations.
摘要真实世界数据(Real world data, RWD)已成为药物研究与开发的重要工具。RWD是在患者与医疗保健系统互动时产生的,在诊断制定和医疗干预措施选择时,RWD是巨大的,在许多方面都是典型的大数据。利用人工智能(AI)分析RWD似乎是一个显而易见的选择。它承诺对医疗需求、疾病驱动因素和药理学干预的新机会有新的见解。在实际应用中,RWD分析具有挑战性。在面向患者而非信息最大化的医疗保健交易中,在次优标准化条件下的分布式数据生成会导致高度稀疏和不受控制的偏差。我们讨论了为什么需要独立于分析方法的类型来解决这个问题。虽然经典的统计分析和建模方法为处理偏差和稀疏性提供了严格的框架,但人工智能方法并不一定适合天真地应用。从选择方法到解释结果都需要采取特别的预防措施,以防止潜在的有害谬误。也可能需要有意识地利用先前的医学主题专门知识。基于典型的应用程序示例,我们说明了挑战和方法上的考虑。
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引用次数: 0
Novel Deep Learning Approaches for Analyzing Diffusion Imaging Data 扩散成像数据分析的新型深度学习方法
Pub Date : 2023-09-28 DOI: 10.1007/s13218-023-00811-y
Yousef Sadegheih, Leon Weninger, Dorit Merhof
Abstract Diffusion magnetic resonance imaging (dMRI) is developing into one of the most important non-invasive tools for clinical brain research. This development is supported by a project funded by the German Research Foundation, in which four major obstacles related to dMRI data were addressed: (1) the lack of transferability of dMRI data between clinical sites, (2) the lack of training and label data, (3) the potential of complex diffusion data, and (4) the integration of spherical signals in neural networks to improve accuracy. To overcome the problem of different MRI systems producing slightly varying data, the project developed a method for harmonizing MRI signals. To address the issue of limited ground truth data, a framework was developed to synthesize individual diffusion data and complete datasets based on important diffusion characteristics and statistics. The integration of complex signals, often discarded during acquisition, to improve reconstruction was also explored. Finally, new methods were developed to preserve the spherical character of the diffusion data in the DL model. The resulting methods are intended to improve the usability of diffusion imaging data and to enable the creation of processing pipelines for dMRI data in clinical studies and clinical practice.
扩散磁共振成像(dMRI)正在发展成为临床脑研究中最重要的非侵入性工具之一。这一发展得到了德国研究基金会资助的一个项目的支持,该项目解决了与dMRI数据相关的四个主要障碍:(1)dMRI数据在临床站点之间缺乏可转移性,(2)缺乏训练和标签数据,(3)复杂扩散数据的潜力,以及(4)在神经网络中集成球形信号以提高准确性。为了克服不同的MRI系统产生略有不同的数据的问题,该项目开发了一种协调MRI信号的方法。为了解决地面真值数据有限的问题,开发了一个基于重要扩散特征和统计的框架来综合单个扩散数据和完整数据集。对采集过程中经常被丢弃的复杂信号进行整合,以提高重建效果也进行了探讨。最后,提出了保留DL模型中扩散数据球形特征的新方法。由此产生的方法旨在提高扩散成像数据的可用性,并在临床研究和临床实践中为dMRI数据创建处理管道。
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引用次数: 0
Designing Expert-Augmented Clinical Decision Support Systems to Predict Mortality Risk in ICUs 设计专家增强临床决策支持系统以预测icu的死亡风险
Pub Date : 2023-08-19 DOI: 10.1007/s13218-023-00808-7
Johannes Chen, Maximilian Lowin, Domenic Kellner, O. Hinz, E. Adam, Angelo Ippolito, Katharina Wenger-Alakmeh
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引用次数: 0
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